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Conserved domains on  [gi|446738887|ref|WP_000816143|]
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MULTISPECIES: DMSO/selenate family reductase complex B subunit [Salmonella]

Protein Classification

DmsB/YnfG family anaerobic dimethyl sulfoxide reductase iron-sulfur subunit( domain architecture ID 11496220)

DmsB/YnfG family anaerobic dimethyl sulfoxide reductase iron-sulfur subunit is the electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds

Gene Ontology:  GO:0051539|GO:0046872|GO:0009061|GO:0009389

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DMSO_dmsB TIGR02951
DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain ...
 3-163 8.56e-106

DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.


:

Pssm-ID: 131996 [Multi-domain]  Cd Length: 161  Bit Score: 300.88  E-value: 8.56e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887    3 QYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWVKEGESWHHDTFTYYLSIACNHCDEPVCVSGCPTGA 82
Cdd:TIGR02951   1 QYGFYVDQTRCSGCKTCQIACKDKNDLEVGVLFRRVYEYEGGGWTEEGEGFHPDVFAYYISISCNHCADPACVKNCPTGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   83 MHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDELRAKY 162
Cdd:TIGR02951  81 MYKREEDGLVLVDQDKCIGCRYCVWACPYGAPQYDPQQGVMGKCDGCYDRVEKGLRPACVDACPMRALDFGPIDELRAKY 160


                  .
gi 446738887  163 G 163
Cdd:TIGR02951 161 G 161
 
Name Accession Description Interval E-value
DMSO_dmsB TIGR02951
DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain ...
 3-163 8.56e-106

DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.


Pssm-ID: 131996 [Multi-domain]  Cd Length: 161  Bit Score: 300.88  E-value: 8.56e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887    3 QYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWVKEGESWHHDTFTYYLSIACNHCDEPVCVSGCPTGA 82
Cdd:TIGR02951   1 QYGFYVDQTRCSGCKTCQIACKDKNDLEVGVLFRRVYEYEGGGWTEEGEGFHPDVFAYYISISCNHCADPACVKNCPTGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   83 MHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDELRAKY 162
Cdd:TIGR02951  81 MYKREEDGLVLVDQDKCIGCRYCVWACPYGAPQYDPQQGVMGKCDGCYDRVEKGLRPACVDACPMRALDFGPIDELRAKY 160


                  .
gi 446738887  163 G 163
Cdd:TIGR02951 161 G 161
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 5-153 2.87e-73

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 217.82  E-value: 2.87e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   5 GFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWvkegeswhHDTFTYYLSIACNHCDEPVCVSGCPTGAMH 84
Cdd:cd16371    1 GFYFDQERCIGCKACEIACKDKNDLPPGVNWRRVYEYEGGEF--------PEVFAYFLSMSCNHCENPACVKVCPTGAIT 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446738887  85 KRkEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFG 153
Cdd:cd16371   73 KR-EDGIVVVDQDKCIGCGYCVWACPYGAPQYNPETGKMDKCDMCVDRLDEGEKPACVAACPTRALDFG 140
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 1-188 2.01e-69

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 209.80  E-value: 2.01e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   1 MKQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWvkegeswhHDTFTYYLSIACNHCDEPVCVSGCPT 80
Cdd:COG0437    3 MKRYGMVIDLTKCIGCRACVVACKEENNLPVGVTWRRVRRYEEGEF--------PNVEWLFVPVLCNHCDDPPCVKVCPT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  81 GAMHKRkEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDELRA 160
Cdd:COG0437   75 GATYKR-EDGIVLVDYDKCIGCRYCVAACPYGAPRFNPETGVVEKCTFCADRLDEGLLPACVEACPTGALVFGDLDDPES 153

                        170       180       190
                 ....*....|....*....|....*....|.
gi 446738887 161 KYGT---ENQIAPLPSASFTHPNLIIKPHPK 188
Cdd:COG0437  154 EVSKrlaELPAYRLLPELGTKPSVYYLPKRN 184
Fer4_11 pfam13247
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 57-153 2.72e-33

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 404184 [Multi-domain]  Cd Length: 99  Bit Score: 115.04  E-value: 2.72e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   57 TFTYYLSIACNHCDEPVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENN 136
Cdd:pfam13247   1 VDWLFFPEQCRHCLNPPCKASCPVGAIYKDEETGAVLLDEKTCRGWRECVSACPYNIPRYNDETGKAEKCDMCYDRVEAG 80

                          90
                  ....*....|....*..
gi 446738887  137 LRPICVDSCPQRALDFG 153
Cdd:pfam13247  81 LLPACVQTCPTGAMNFG 97
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
9-160 1.78e-29

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 111.30  E-value: 1.78e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   9 DSSRCSGCKTCQVSCKDNKDLDVGPKlrrvyeyGGGSW----------------VKEGESWHHDTFT---YYLSIACNHC 69
Cdd:PRK10882  43 DSTLCVGCQACVTKCQEINFPERNPQ-------GEQTWdnpdklspytnniikvWKSGTGVNKDQEEngyAYIKKQCMHC 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  70 DEPVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMR--KCDGC----LDRLENNLRPICVD 143
Cdd:PRK10882 116 VDPNCVSVCPVSALTKDPKTGIVHYDKDVCTGCRYCMVACPFNVPKYDYNNPFGAihKCELCnqkgVERLDKGGLPGCVE 195

                        170
                 ....*....|....*..
gi 446738887 144 SCPQRALDFGPVDELRA 160
Cdd:PRK10882 196 VCPTGAVIFGTREELLA 212
 
Name Accession Description Interval E-value
DMSO_dmsB TIGR02951
DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain ...
 3-163 8.56e-106

DMSO reductase, iron-sulfur subunit; This family consists of the iron-sulfur subunit, or chain B, of an enzyme called the anaerobic dimethyl sulfoxide reductase. Chains A and B are catalytic, while chain C is a membrane anchor.


Pssm-ID: 131996 [Multi-domain]  Cd Length: 161  Bit Score: 300.88  E-value: 8.56e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887    3 QYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWVKEGESWHHDTFTYYLSIACNHCDEPVCVSGCPTGA 82
Cdd:TIGR02951   1 QYGFYVDQTRCSGCKTCQIACKDKNDLEVGVLFRRVYEYEGGGWTEEGEGFHPDVFAYYISISCNHCADPACVKNCPTGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   83 MHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDELRAKY 162
Cdd:TIGR02951  81 MYKREEDGLVLVDQDKCIGCRYCVWACPYGAPQYDPQQGVMGKCDGCYDRVEKGLRPACVDACPMRALDFGPIDELRAKY 160


                  .
gi 446738887  163 G 163
Cdd:TIGR02951 161 G 161
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 5-153 2.87e-73

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 217.82  E-value: 2.87e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   5 GFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWvkegeswhHDTFTYYLSIACNHCDEPVCVSGCPTGAMH 84
Cdd:cd16371    1 GFYFDQERCIGCKACEIACKDKNDLPPGVNWRRVYEYEGGEF--------PEVFAYFLSMSCNHCENPACVKVCPTGAIT 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446738887  85 KRkEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFG 153
Cdd:cd16371   73 KR-EDGIVVVDQDKCIGCGYCVWACPYGAPQYNPETGKMDKCDMCVDRLDEGEKPACVAACPTRALDFG 140
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 1-188 2.01e-69

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 209.80  E-value: 2.01e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   1 MKQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGSWvkegeswhHDTFTYYLSIACNHCDEPVCVSGCPT 80
Cdd:COG0437    3 MKRYGMVIDLTKCIGCRACVVACKEENNLPVGVTWRRVRRYEEGEF--------PNVEWLFVPVLCNHCDDPPCVKVCPT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  81 GAMHKRkEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDELRA 160
Cdd:COG0437   75 GATYKR-EDGIVLVDYDKCIGCRYCVAACPYGAPRFNPETGVVEKCTFCADRLDEGLLPACVEACPTGALVFGDLDDPES 153

                        170       180       190
                 ....*....|....*....|....*....|.
gi 446738887 161 KYGT---ENQIAPLPSASFTHPNLIIKPHPK 188
Cdd:COG0437  154 EVSKrlaELPAYRLLPELGTKPSVYYLPKRN 184
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 8-153 4.40e-45

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 148.06  E-value: 4.40e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   8 VDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGswvkegesWHHDTFTYYLSIACNHCDEPVCVSGCPTGAMHKRk 87
Cdd:cd10551    3 IDLRKCIGCGACVVACKAENNVPPGVFRNRVLEYEVG--------EYPNVKRTFLPVLCNHCENPPCVKVCPTGATYKR- 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446738887  88 EDGLVVVDDSVCVGCRYCEMRCPYGAPQFD------------TQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFG 153
Cdd:cd10551   74 EDGIVLVDYDKCIGCRYCMAACPYGARYFNpeephefgevpvRPKGVVEKCTFCYHRLDEGLLPACVEACPTGARIFG 151
PhsB_like cd10553
uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This ...
 4-153 3.21e-43

uncharacterized beta subfamily of DMSO Reductase similar to Desulfonauticus sp PhsB; This family includes beta FeS subunits of anaerobic DMSO reductase (DMSOR) superfamily that have yet to be characterized. DMSOR consists of a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and the tungsten-containing formate dehydrogenase (FDH-T). Examples of heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319875 [Multi-domain]  Cd Length: 146  Bit Score: 141.73  E-value: 3.21e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   4 YGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGgswvkegESWHHDTFTYYLSIACNHCDEPVCVSGCPTGAM 83
Cdd:cd10553    3 YYLYHDSKRCIGCLACEVHCKVKNNLPVGPRLCRIFAVGP-------KMVGGKPRLKFVYMSCFHCENPWCVKACPTGAM 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  84 HKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFG 153
Cdd:cd10553   76 QKREKDGIVYVDQELCIGCKACIEACPWGIPQWNPATGKVVKCDYCMDRIDQGLKPACVTGCTTHALSFV 145
HybA_like cd10561
the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 ...
 5-160 1.16e-42

the FeS subunit of hydrogenase 2; This subfamily includes the beta-subunit of hydrogenase 2 (Hyd-2), an enzyme that catalyzes the reversible oxidation of H2 to protons and electrons. Hyd-2 is membrane-associated and forms an unusual heterotetrameric [NiFe]-hydrogenase in that it lacks the typical cytochrome b membrane anchor subunit that transfers electrons to the quinone pool. The electron transfer subunit of Hyd-2 (HybA) which is predicted to contain four iron-sulfur clusters, is essential for electron transfer from Hyd-2 to menaquinone/demethylmenaquinone (MQ/DMQ) to couple hydrogen oxidation to fumarate reduction.


Pssm-ID: 319883 [Multi-domain]  Cd Length: 196  Bit Score: 141.97  E-value: 1.16e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   5 GFYVDSSRCSGCKTCQVSCKDNKDLDVGPK-----LRRVYEYGGGSW--VKEGESWHHDTFTYYLSIACNHCDEPVCVSG 77
Cdd:cd10561    1 GVLYDTTRCIGCRACEVACKEWNGLPAEDTafgpgWDNPRDLSAKTYtvIKRYEVETGGKGFVFVKRQCMHCLDPACVSA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  78 CPTGAMHKRKEdGLVVVDDSVCVGCRYCEMRCPYGAPQF--DTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPV 155
Cdd:cd10561   81 CPVGALRKTPE-GPVTYDEDKCIGCRYCMVACPFNIPKYewDSANPKIRKCTMCYDRLKEGKQPACVEACPTGALLFGKR 159


                 ....*
gi 446738887 156 DELRA 160
Cdd:cd10561  160 EELLA 164
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 7-158 1.72e-41

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 137.82  E-value: 1.72e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   7 YVDSSRCSGCKTCQVSCKDNKDL---------------DVGPKLR---RVYEYGGGswvKEGESWhhdtftYYLSIACNH 68
Cdd:cd10562    2 LVDTSKCTACRGCQVACKQWNQLpaektpftgsyqnppDLTPNTWtliRFYEHEED---NGGIRW------LFRKRQCMH 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  69 CDEPVCVSGCPTGAMHKrKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQR 148
Cdd:cd10562   73 CTDAACVKVCPTGALYK-TENGAVVVDEDKCIGCGYCVAACPFDVPRYDETTNKITKCTLCFDRIENGMQPACVKTCPTG 151

                        170
                 ....*....|
gi 446738887 149 ALDFGPVDEL 158
Cdd:cd10562  152 ALTFGDRDEL 161
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 6-153 1.94e-41

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 137.53  E-value: 1.94e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   6 FYVDSSRCSGCKTCQVSCKDNKDL-DVGPKLRRVYEY----GGGSW----VKEGESWHHDTFTYYLSIACNHCDEPVCVS 76
Cdd:cd16366    1 FLVDTSRCTGCRACQVACKQWNGLpAEKTEFTGSYQNppdlTAHTWtlvrFYEVEKPGGDLSWLFRKDQCMHCTDAGCLA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446738887  77 GCPTGAMHKRkEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFG 153
Cdd:cd16366   81 ACPTGAIIRT-ETGTVVVDPETCIGCGYCVNACPFDIPRFDEETGRVAKCTLCYDRISNGLQPACVKTCPTGALTFG 156
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 6-153 5.57e-41

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 135.98  E-value: 5.57e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   6 FYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYGGGswvkegeswhhDTFTYYLSIACNHCDEPVCVSGCPTGAMHK 85
Cdd:cd04410    1 LVVDLDRCIGCGTCEVACKQEHGLRPGPDWSRIKVIEGG-----------GLERAFLPVSCMHCEDPPCVKACPTGAIYK 69

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446738887  86 RkEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFG 153
Cdd:cd04410   70 D-EDGIVLIDEDKCIGCGSCVEACPYGAIVFDPEPGKAVKCDLCGDRLDEGLEPACVKACPTGALTFG 136
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 5-161 3.22e-35

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 124.04  E-value: 3.22e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   5 GFYVDSSRCSGCKTCQVSCKDNKDLDVGPklrrvYEYGGGSWVKEG----ESWHHDTFT-----------------YYLS 63
Cdd:cd10560    1 GFFTDTSICIGCKACEVACKQWNQLPADG-----YDFSGMSYDNTGdlsaSTWRHVKFIerptedgpaneggdlqwLFMS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  64 IACNHCDEPVCVSGCPTGAMHkRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVD 143
Cdd:cd10560   76 DVCKHCTDAGCLEACPTGAIF-RTEFGTVYIQPDICNGCGYCVAACPFGVIDRNEETGRAHKCTLCYDRLKDGLEPACAK 154

                        170
                 ....*....|....*...
gi 446738887 144 SCPQRALDFGPVDELRAK 161
Cdd:cd10560  155 ACPTGSIQFGPLEELRER 172
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 7-161 4.47e-35

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 120.84  E-value: 4.47e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   7 YVDSSRCSGCKTCQVSCkdnkDLDVGPKLR-RVYEYGGGswvkegeswhhdtftYYLSIACNHCDEPVCVSGCPTGAMHk 85
Cdd:cd16374    2 YVDPERCIGCRACEIAC----AREHSGKPRiSVEVVEDL---------------ASVPVRCRHCEDAPCMEVCPTGAIY- 61

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446738887  86 RKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDELRAK 161
Cdd:cd16374   62 RDEDGAVLVDPDKCIGCGMCAMACPFGVPRFDPSLKVAVKCDLCIDRRREGKLPACVEACPTGALKFGDIEELLKE 137
CooF_like cd10563
CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the ...
 7-153 9.25e-34

CooF, iron-sulfur subunit of carbon monoxide dehydrogenase; This family includes CooF, the iron-sulfur subunit of carbon monoxide dehydrogenase (CODH), found in anaerobic bacteria and archaea. Carbon monoxide dehydrogenase is a key enzyme for carbon monoxide (CO) metabolism, where CooF is the proposed mediator of electron transfer between CODH and the CO-induced hydrogenase, catalyzing the reaction that uses CO as a single carbon and energy source, and producing only H2 and CO2. The ion-sulfur subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons in the protein complex during reaction.


Pssm-ID: 319885 [Multi-domain]  Cd Length: 140  Bit Score: 117.36  E-value: 9.25e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   7 YVDSSRCSGCKTCQVSCK----DNKDL------DVGPKLRRVYEYGGGswvkegeswhhdtftYYLSIACNHCDEPVCVS 76
Cdd:cd10563    3 FIDEEKCLGCKLCEVACAvahsKSKDLikakleKERPRPRIRVEESGG---------------RSFPLQCRHCDEPPCVK 67

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446738887  77 GCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLEnnlrPICVDSCPQRALDFG 153
Cdd:cd10563   68 ACMSGAMHKDPETGIVIHDEEKCVGCWMCVMVCPYGAIRPDKERKVALKCDLCPDRET----PACVEACPTGALVLE 140
Fer4_11 pfam13247
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 57-153 2.72e-33

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 404184 [Multi-domain]  Cd Length: 99  Bit Score: 115.04  E-value: 2.72e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   57 TFTYYLSIACNHCDEPVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENN 136
Cdd:pfam13247   1 VDWLFFPEQCRHCLNPPCKASCPVGAIYKDEETGAVLLDEKTCRGWRECVSACPYNIPRYNDETGKAEKCDMCYDRVEAG 80

                          90
                  ....*....|....*..
gi 446738887  137 LRPICVDSCPQRALDFG 153
Cdd:pfam13247  81 LLPACVQTCPTGAMNFG 97
EBDH_beta cd10555
beta subunit of ethylbenzene-dehydrogenase (EBDH); This subfamily includes ethylbenzene ...
 1-201 6.71e-31

beta subunit of ethylbenzene-dehydrogenase (EBDH); This subfamily includes ethylbenzene dehydrogenase (EBDH, EC 1.17.99.2), a member of the DMSO reductase family. EBDH oxidizes the hydrocarbon ethylbenzene to (S)-1-phenylethanol. It is a heterotrimer, with the alpha subunit containing the catalytic center with a molybdenum held by two molybdopterin-guanine dinucleotides, the beta subunit containing four iron-sulfur clusters (the electron transfer subunit) and the gamma subunit containing a methionine and a lysine as axial heme ligands. During catalysis, electrons produced by substrate oxidation are transferred to a heme in the gamma subunit and then presumably to a separate cytochrome involved in nitrate respiration.


Pssm-ID: 319877 [Multi-domain]  Cd Length: 316  Bit Score: 114.71  E-value: 6.71e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   1 MKQYGFYVDSSRCSGCKTCQVSCK--------------DNKDLDVGPKLRRVYEYGGGSWVKEGE--------------- 51
Cdd:cd10555    2 KRQLAMVMDLNKCIGCQTCTVACKtlwtnrngreymywNNVETQPGKGYPKNWEKKGGGFKDKGElkpgiiptledygvp 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  52 ---SWHHDTFT----------------------------------YYLSIACNHCDEPVCVSGCPTGAMHKRKEDGLVVV 94
Cdd:cd10555   82 weyNHEEELFEgkggrvrpspkgdptwgpnwdedqgageypnsyyFYLPRICNHCTNPACLAACPRKAIYKREEDGIVLV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  95 DDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDE----------------- 157
Cdd:cd10555  162 DQDRCRGYRYCVEACPYKKIYFNPVEQKSEKCIFCYPRIEKGVAPACARQCVGRIRFVGYLDDeespvyklvkkwkvalp 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446738887 158 LRAKYGTEnqiaplpsasfthPNLIIKPhPKARPTGDTEGAIMN 201
Cdd:cd10555  242 LHPEYGTE-------------PNVFYVP-PLSPPKLGDDGEPTD 271
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
9-160 1.78e-29

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 111.30  E-value: 1.78e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   9 DSSRCSGCKTCQVSCKDNKDLDVGPKlrrvyeyGGGSW----------------VKEGESWHHDTFT---YYLSIACNHC 69
Cdd:PRK10882  43 DSTLCVGCQACVTKCQEINFPERNPQ-------GEQTWdnpdklspytnniikvWKSGTGVNKDQEEngyAYIKKQCMHC 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  70 DEPVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMR--KCDGC----LDRLENNLRPICVD 143
Cdd:PRK10882 116 VDPNCVSVCPVSALTKDPKTGIVHYDKDVCTGCRYCMVACPFNVPKYDYNNPFGAihKCELCnqkgVERLDKGGLPGCVE 195

                        170
                 ....*....|....*..
gi 446738887 144 SCPQRALDFGPVDELRA 160
Cdd:PRK10882 196 VCPTGAVIFGTREELLA 212
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 7-152 6.50e-29

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 104.58  E-value: 6.50e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   7 YVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYgggSWVKEGeswhhdtftYYLSIACNHCDEPVCVSGCPTGAMHKR 86
Cdd:cd10550    2 VVDPEKCTGCRTCELACSLKHEGVFNPSLSRIRVV---RFEPEG---------LDVPVVCRQCEDAPCVEACPVGAISRD 69

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446738887  87 KEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDrlennlRPICVDSCPQRALDF 152
Cdd:cd10550   70 EETGAVVVDEDKCIGCGMCVEACPFGAIRVDPETGKAIKCDLCGG------DPACVKVCPTGALEF 129
NarH_like cd16365
beta FeS subunits DMSOR NarH-like family; This subfamily contains beta FeS subunits of several ...
 2-172 7.54e-29

beta FeS subunits DMSOR NarH-like family; This subfamily contains beta FeS subunits of several DMSO reductase superfamily, including nitrate reductase A, ethylbenzene dehydrogenase and selenate reductase. DMSO Reductase (DMSOR) family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. . The beta subunits of DMSOR contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system. Nitrate reductase A contains three subunits (the catalytic subunit NarG, the catalytic subunit NarH with four [Fe-S] clusters, and integral membrane subunit NarI) and often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Ethylbenzene dehydrogenase oxidizes the hydrocarbon ethylbenzene to (S)-1-phenylethanol. Selenate reductase catalyzes reduction of selenate to selenite in bacterial species that can obtain energy by respiring anaerobically with selenate as the terminal electron acceptor.


Pssm-ID: 319887 [Multi-domain]  Cd Length: 201  Bit Score: 106.90  E-value: 7.54e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   2 KQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRR-----VYEYGG--GSW-VKEGESWHHDTFTYYLSIACNHCDEPV 73
Cdd:cd16365    1 KQFAAVFNLNKCIGCQTCTVACKNAWTYRKGQEYMWwnnveTKPGGGypQDWeVKTIDNGGNTRFFFYLQRLCNHCTNPA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  74 CVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFG 153
Cdd:cd16365   81 CLAACPRGAIYKREEDGIVLIDQKRCRGYRKCVEQCPYKKIYFNGLSRVSEKCIACYPRIEGGDPTRCMSACVGRIRLQG 160

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 446738887 154 PVDE------------------LRAKYGTENQIAPLP 172
Cdd:cd16365  161 FLDDnpkspvtklirhwkvalpLHPEYGTEPNIYYVP 197
DMSOR_beta_like cd16369
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 3-161 1.03e-28

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319891 [Multi-domain]  Cd Length: 172  Bit Score: 105.55  E-value: 1.03e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   3 QYGFYVDSSRCSGCKTCQVSCKDNKDLDvgpKLRRVYEYgggsWVKEGESwhhdtfTYYLSIACNHCDEPVCVSGCPTGA 82
Cdd:cd16369    1 EKEFFIDPSRCIGCRACVAACRECGTHR---GKSMIHVD----YIDRGES------TQTAPTVCMHCEDPTCAEVCPADA 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  83 MhKRKEDGLVV-VDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDELRAK 161
Cdd:cd16369   68 I-KVTEDGVVQsALKPRCIGCSNCVNACPFGVPKYDEERNLMMKCDMCYDRTSVGKAPMCASVCPSGALFYGTREEIQAL 146
PRK14993 PRK14993
tetrathionate reductase subunit TtrB;
2-145 3.79e-28

tetrathionate reductase subunit TtrB;


Pssm-ID: 184955 [Multi-domain]  Cd Length: 244  Bit Score: 106.11  E-value: 3.79e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   2 KQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEYgggswvKEGESWHHDTFTYYLSIACNHCDEPVCVSGCPTG 81
Cdd:PRK14993  42 HRYAMLIDLRRCIGCQSCTVSCTIENQTPQGAFRTTVNQY------QVQREGSQEVTNVLLPRLCNHCDNPPCVPVCPVQ 115

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446738887  82 AMHKRKeDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSC 145
Cdd:PRK14993 116 ATFQRE-DGIVVVDNKRCVGCAYCVQACPYDARFINHETQTADKCTFCVHRLEAGLLPACVESC 178
TH_beta_N cd10552
N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This ...
 6-186 1.79e-27

N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This family includes the beta subunit of pyrogallol-phloroglucinol transhydroxylase (TH), a cytoplasmic molybdenum (Mo) enzyme from anaerobic microorganisms like Pelobacter acidigallici and Desulfitobacterium hafniense which catalyzes the conversion of pyrogallol to phloroglucinol, an important building block of plant polymers. TH belongs to the DMSO reductase (DMSOR) family; it is a heterodimer consisting of a large alpha catalytic subunit and a small beta FeS subunit. The beta subunit has two domains with the N-terminal domain containing three [4Fe-4S] centers and a seven-stranded, mainly antiparallel beta-barrel domain. In the anaerobic bacterium Pelobacter acidigallici, gallic acid, pyrogallol, phloroglucinol, or phloroglucinol carboxylic acid are fermented to three molecules of acetate (plus CO2), and TH is the key enzyme in the fermentation pathway, which converts pyrogallol to phloroglucinol in the absence of O2.


Pssm-ID: 319874 [Multi-domain]  Cd Length: 186  Bit Score: 102.79  E-value: 1.79e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   6 FYVDSSRCSGCKTCQVSCKDnkdldvgpklrrvyEYGGGSW-------VKEGESW------HHDTF----TYYLSIACNH 68
Cdd:cd10552    1 LVIDVAKCNGCYNCFLACKD--------------EHVGNDWpgyaapqPRHGHFWmrilrrERGQYpkvdVAYLPVPCNH 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  69 CDEPVCVSGCPTGAMHKRkEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENN-LRPICVDSCPQ 147
Cdd:cd10552   67 CDNAPCIKAAKDGAVYKR-DDGIVIIDPEKAKGQKQLVDACPYGAIYWNEELQVPQKCTFCAHLLDDGwKEPRCVQACPT 145

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 446738887 148 RALDFGPVDELRAKYGTENQiaplpSASFTHPNLIIKPH 186
Cdd:cd10552  146 GALRFGKLEDEEMAAKAAEE-----GLEVLHPELGTKPR 179
FDH-N cd10558
The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS ...
 8-181 2.98e-27

The beta FeS subunit of formate dehydrogenase-N (FDH-N); This subfamily contains beta FeS subunit of formate dehydrogenase-N (FDH-N), a member of the DMSO reductase family. FDH-N is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. Thus, FDH-N is a major component of nitrate respiration of Escherichia coli. This integral membrane enzyme forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups.


Pssm-ID: 319880 [Multi-domain]  Cd Length: 208  Bit Score: 102.85  E-value: 2.98e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   8 VDSSRCSGCKTCQVSCKDNKDL-DVGPKLRRVYE----YGGGSW--VKEGESWHHDTFTYYLSI-ACNHCDEPVCVSGCP 79
Cdd:cd10558    4 IDVSKCIGCKACQVACKEWNDLrAEVGHNVGTYQnpadLSPETWtlMKFREVEDNGKLEWLIRKdGCMHCADPGCLKACP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  80 TGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALDFGPVDELR 159
Cdd:cd10558   84 SPGAIVQYANGIVDFQSDKCIGCGYCIKGCPFDIPRISKDDNKMYKCTLCSDRVSVGLEPACVKTCPTGALHFGTKEDML 163

                        170       180
                 ....*....|....*....|..
gi 446738887 160 AKygTENQIAPLPSASFTHPNL 181
Cdd:cd10558  164 AL--AEKRVAALKERGYTNAGL 183
SER_beta cd10556
Beta subunit of selenate reductase; This subfamily includes beta FeS subunit of selenate ...
 55-146 2.84e-25

Beta subunit of selenate reductase; This subfamily includes beta FeS subunit of selenate reductase (SER), a member of the DMSO reductase family. SER catalyzes the reduction of selenate to selenite in bacterial species that can obtain energy by respiring anaerobically with selenate as the terminal electron acceptor. The enzyme comprises three subunits SerABC, forming a heterotrimer, with the catalytic component (alpha-subunit), iron-sulfur protein (beta-subunit) and monomeric b-type heme-containing gamma subunit. Beta subunit contains coordinating one [3Fe-4S] cluster and three [4Fe-4S] clusters and functions as electron carrier.


Pssm-ID: 319878 [Multi-domain]  Cd Length: 287  Bit Score: 99.46  E-value: 2.84e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  55 HDTFTYYLSIACNHCDEPVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLE 134
Cdd:cd10556  130 HPIWFFYLPRICNHCTYPACLAACPRKAIYKREEDGIVLIDQERCRGYRECVEACPYKKPMYNPTTRVSEKCIGCYPRIE 209

                         90
                 ....*....|..
gi 446738887 135 NNLRPICVDSCP 146
Cdd:cd10556  210 EGDQTQCVSACI 221
NarH_beta-like cd10557
beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes ...
 55-145 3.25e-25

beta subunit of nitrate reductase A (NarH) and similar proteins; This subfamily includes nitrate reductase A, a member of the DMSO reductase family. The respiratory nitrate reductase complex (NarGHI) from E. coli is a heterotrimer, with the catalytic subunit (NarG) with a molybdo-bis (molybdopterin guanine dinucleotide) cofactor and an [Fe-S] cluster, the electron transfer subunit (NarH) with four [Fe-S] clusters, and the integral membrane subunit (NarI) with two b-type hemes. Nitrate reductase A often forms a respiratory chain with the formate dehydrogenase via the lipid soluble quinol pool. Electron transfer from formate to nitrate is coupled to proton translocation across the cytoplasmic membrane generating proton motive force by a redox loop mechanism. Demethylmenaquinol (DMKH2) has been shown to be a good substrate for NarGHI in nitrate respiration in E. coli.


Pssm-ID: 319879 [Multi-domain]  Cd Length: 363  Bit Score: 100.51  E-value: 3.25e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  55 HDTFTYYLSIACNHCDEPVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLE 134
Cdd:cd10557  168 ENTFMFYLPRICNHCLNPACVAACPSGAIYKREEDGIVLIDQDRCRGWRMCVSACPYKKVYYNWKTGKSEKCIFCYPRLE 247

                         90
                 ....*....|.
gi 446738887 135 NNLRPICVDSC 145
Cdd:cd10557  248 AGQPTVCSETC 258
DMSOR_beta_like cd16368
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 66-161 7.91e-23

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319890 [Multi-domain]  Cd Length: 200  Bit Score: 90.94  E-value: 7.91e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  66 CNHCDEPVCVSGCPTGAMHKRKEdGLVVVDDSVCVGCRYCEMRCPYGAPQfdTQANV---------------MRKCDGCL 130
Cdd:cd16368   91 CMHCDNPPCAKLCPFGAARKTPE-GAVYIDDDLCFGGAKCRDVCPWHIPQ--RQAGVgiylhlapeyagggvMYKCDLCK 167

                         90       100       110
                 ....*....|....*....|....*....|.
gi 446738887 131 DRLENNLRPICVDSCPQRALDFGPVDELRAK 161
Cdd:cd16368  168 DLLAQGKPPACIEACPKGAQYFGPRKEMVAL 198
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
7-150 8.00e-23

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 89.33  E-value: 8.00e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   7 YVDSSRCSGCKTCQVSCKDNKDLDVGPKLR---RVYEYGGGSwvkegeswhhdtftyyLSIACNHCDEPVCVSGCPTGAM 83
Cdd:COG1142    6 IADPEKCIGCRTCEAACAVAHEGEEGEPFLpriRVVRKAGVS----------------APVQCRHCEDAPCAEVCPVGAI 69

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446738887  84 HKrkEDGLVVVDDSVCVGCRYCEMRCPYGA--PQFDTQANVMRKCDGCLDRLENnlrPICVDSCPQRAL 150
Cdd:COG1142   70 TR--DDGAVVVDEEKCIGCGLCVLACPFGAitMVGEKSRAVAVKCDLCGGREGG---PACVEACPTGAL 133
W-FDH cd10559
tungsten-containing formate dehydrogenase, small subunit; This subfamily contains beta subunit ...
 5-160 1.32e-22

tungsten-containing formate dehydrogenase, small subunit; This subfamily contains beta subunit of Tungsten-containing formate dehydrogenase (W-FDH), a member of the DMSO reductase family. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319881 [Multi-domain]  Cd Length: 200  Bit Score: 90.57  E-value: 1.32e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   5 GFYVDSSRCSGCKTCQVSCKDNKDLDVGP-KLRRVYE----YGGGSW--VKEGESWHHDTFTYYLSIA--CNHCDEPVCV 75
Cdd:cd10559    1 SFLIDTTRCTACRGCQVACKQWNQLPAEQtKNTGSHQnppdLSANTYklVRFNEVRNENGKPDWLFFPdqCRHCVTPPCK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  76 SGCP--TGAMHKRKEDGLVVVDDSVCVGCrYCEMR--CPYGAPQFDTQANVMRKCDGCLDRLENNLRPICVDSCPQRALD 151
Cdd:cd10559   81 DAADmvPGAVIQDEATGAVVFTEKTAELD-FDDVLsaCPYNIPRKNEATGRIVKCDMCIDRVSNGLQPACVKACPTGAMN 159


                 ....*....
gi 446738887 152 FGPVDELRA 160
Cdd:cd10559  160 FGDRDEMLA 168
NarY COG1140
Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and ...
 56-148 7.62e-22

Nitrate reductase beta subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440755 [Multi-domain]  Cd Length: 485  Bit Score: 92.18  E-value: 7.62e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  56 DTFTYYLSIACNHCDEPVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDRLEN 135
Cdd:COG1140  172 NTFMFYLPRICEHCLNPACVASCPSGAIYKREEDGIVLVDQDKCRGWRMCVSGCPYKKVYFNWKTGKAEKCIFCYPRIEA 251

                         90
                 ....*....|...
gi 446738887 136 NLRPICVDSCPQR 148
Cdd:COG1140  252 GQPTVCSETCVGR 264
cyt_nit_nrfC TIGR03149
cytochrome c nitrite reductase, Fe-S protein; Members of this protein family are the Fe-S ...
 2-193 9.17e-22

cytochrome c nitrite reductase, Fe-S protein; Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport]


Pssm-ID: 274451 [Multi-domain]  Cd Length: 225  Bit Score: 88.69  E-value: 9.17e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887    2 KQYGFYVDSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEygggswvKEGESWHHDTFTYYLSIACNHCDEPVCVSGCPTG 81
Cdd:TIGR03149  37 KRYGMVHDETACIGCTACMDACREVNKVPEGVSRLEIIR-------SEPYGEFPDVEYRFFRKSCQHCDNAPCVAVCPTG 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   82 AMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLD-RLENNLRPICVDSCPQRALDFG----PVD 156
Cdd:TIGR03149 110 ASFKDEETGIVDVHKDLCVGCQYCIAACPYRVRFIHPVTKSADKCNFCRDtNLAEGKLPACVESCPTKALTFGdlndPNS 189

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 446738887  157 ELRAKYgTENQIAPLPSASFTHPNLIIKPHPKARPTG 193
Cdd:TIGR03149 190 EVSQKL-KQKPVYRTKVELGTKPKLYKIPFKKGEVRR 225
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 7-150 1.36e-21

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 86.54  E-value: 1.36e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   7 YVDSSRCSGCKTCQVSC-----------KDNKDLDVGPKLRRVYEYGGgswvkegeswhhdtftyYLSIACNHCDEPVCV 75
Cdd:cd10554    3 IADPDKCIGCRTCEVACaaahsgkgifeAGTDGLPFLPRLRVVKTGEV-----------------TAPVQCRQCEDAPCA 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  76 SGCPTGAMhkRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQF-----------DTQANVMRKCDGCLDRLENnlrPICVDS 144
Cdd:cd10554   66 NVCPVGAI--SQEDGVVQVDEERCIGCKLCVLACPFGAIEMapttvpgvdweRGPRAVAVKCDLCAGREGG---PACVEA 140


                 ....*.
gi 446738887 145 CPQRAL 150
Cdd:cd10554  141 CPTKAL 146
PRK09898 PRK09898
ferredoxin-like protein;
11-150 3.28e-19

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 81.81  E-value: 3.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  11 SRCSGCKTCQVSCKDNKDLDVGP-----KLRRVYEYGGGSWVKEGESWHHDTFTyylSIACNHCDEPVCVSGCPTGAMHK 85
Cdd:PRK09898  66 ARCTGCHRCEISCTNFNDGSVGTffsriKIHRNYFFGDNGVGSGGGLYGDLNYT---ADTCRQCKEPQCMNVCPIGAITW 142

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446738887  86 RKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCLDrlennlrpiCVDSCPQRAL 150
Cdd:PRK09898 143 QQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGE---------CANACPTGAL 198
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 9-150 2.78e-17

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 79.30  E-value: 2.78e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   9 DSSRCSGCKTCQVSCKDNKDLDVGPKLR-----RVYEYGGGSWVKegeswhhdtftyylSIACNHCDEPVCVSGCPTGAM 83
Cdd:PRK12809   8 EAAECIGCHACEIACAVAHNQENWPLSHsdfrpRIHVVGKGQAAN--------------PVACHHCNNAPCVTACPVNAL 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446738887  84 HKRKEDglVVVDDSVCVGCRYCEMRCPYGApqFDTQANVMRKCDGCldrlenNLRP----ICVDSCPQRAL 150
Cdd:PRK12809  74 TFQSDS--VQLDEQKCIGCKRCAIACPFGV--VEMVDTIAQKCDLC------NQRSsgtqACIEVCPTQAL 134
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 9-150 2.97e-15

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 73.63  E-value: 2.97e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   9 DSSRCSGCKTCQVSCKDNKDLDVGPKLRRVYEygggSWVKEGESWHHDTftyylSIACNHCDEPVCVSGCPTGAMhKRKE 88
Cdd:PRK12769   8 NSQQCLGCHACEIACVMAHNDEQHVLSQHHFH----PRITVIKHQQQRS-----AVTCHHCEDAPCARSCPNGAI-SHVD 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446738887  89 DGLVVVDDSvCVGCRYCEMRCPYGAPQFDTQA-------NVMRKCDGCLDRLENnlrPICVDSCPQRAL 150
Cdd:PRK12769  78 DSIQVNQQK-CIGCKSCVVACPFGTMQIVLTPvaagkvkATAHKCDLCAGRENG---PACVENCPADAL 142
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 65-150 1.29e-14

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 67.72  E-value: 1.29e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  65 ACNHCDEPVCVSGCPTGAMHkRKEDGLVVVDDSvCVGCRYCEMRCPYGAPQFDtqanVMRKCDGCLDRLEnnlrPICVDS 144
Cdd:cd16367   56 ACRHCVDPVCMIGCPTGAIH-RDDGGEVVISDA-CCGCGNCASACPYGAIQMV----RAVKCDLCAGYAG----PACVSA 125


                 ....*.
gi 446738887 145 CPQRAL 150
Cdd:cd16367  126 CPTGAA 131
PRK10330 PRK10330
electron transport protein HydN;
8-150 9.69e-12

electron transport protein HydN;


Pssm-ID: 182382 [Multi-domain]  Cd Length: 181  Bit Score: 61.06  E-value: 9.69e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   8 VDSSRCSGCKTCQVSC----KDNKD---LDVGPKLRRVYEYGGgswvkegeswhhdtFTYYLSIACNHCDEPVCVSGCPT 80
Cdd:PRK10330   7 ADASKCIGCRTCEVACvvshQENQDcasLTPETFLPRIHVIKG--------------VNVSTATVCRQCEDAPCANVCPN 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  81 GAMhkRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQAnVMR----------------KCDGCLDRLENnlrPICVDS 144
Cdd:PRK10330  73 GAI--SRDKGFVHVMQERCIGCKTCVVACPYGAMEVVVRP-VIRnsgaglnvraekaeanKCDLCNHREDG---PACMAA 146


                 ....*.
gi 446738887 145 CPQRAL 150
Cdd:PRK10330 147 CPTHAL 152
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 8-152 4.21e-11

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 58.05  E-value: 4.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   8 VDSSRCSGCKTCQVSC--KDNKDLDVGPKLRRVYEYGGGSwvkegeswhhdtfTYYLSIACNHCDEPVCVSGCPTGAMHK 85
Cdd:cd16370    6 KDMERCIGCYSCMLACsrRVHKSASLSKSAIRVRTRGGLE-------------GGFTVVVCRACEDPPCAEACPTGALEP 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446738887  86 RKeDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCldrlennlrPICVDSCPQRALDF 152
Cdd:cd16370   73 RK-GGGVVLDKEKCIGCGNCVKACIVGAIFWDEETNKPIICIHC---------GYCARYCPHDVLAM 129
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
71-153 5.52e-08

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 51.60  E-value: 5.52e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  71 EPVCVSGCPTGAMHK--RKEDGLVV-VDDSVCVGCRYCEMRCPYGAPQFDTQANvMRKCDGCLDrlennlrpiCVDSCPQ 147
Cdd:COG0348  181 RQWCRYLCPYGAFQGllSDLSTLRVrYDRGDCIDCGLCVKVCPMGIDIRKGEIN-QSECINCGR---------CIDACPK 250


                 ....*.
gi 446738887 148 RALDFG 153
Cdd:COG0348  251 DAIRFS 256
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
93-152 5.53e-08

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 52.17  E-value: 5.53e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446738887  93 VVDDSVCVGCRYCEMRCPYGAPQFDTQANVM---RKCDGCldrlennlrPICVDSCPQRALDF 152
Cdd:COG1148  492 EVDPEKCTGCGRCVEVCPYGAISIDEKGVAEvnpALCKGC---------GTCAAACPSGAISL 545
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 9-150 1.61e-07

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 48.49  E-value: 1.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   9 DSSRCSGCKTCQVSCKD--NKDLDVGPKLRRVYEYGGGswvkegeswhhdtftyYLSIACNHCDEpvCVSGCPTGAMhKR 86
Cdd:cd16372    6 DPEKCIGCLQCEEACSKtfFKEEDREKSCIRITETEGG----------------YAINVCNQCGE--CIDVCPTGAI-TR 66

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446738887  87 KEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRKCDGCldrlennlrPICVDSCPQRAL 150
Cdd:cd16372   67 DANGVVMINKKLCVGCLMCVGFCPEGAMFKHEDYPEPFKCIAC---------GICVKACPTGAL 121
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
66-126 1.25e-06

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 44.72  E-value: 1.25e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446738887  66 CNHCDepVCVSGCPTGAMHKrkEDGLVVVDDSVCVGCRYCEMRCPYGA--PQFDTQANVMRKC 126
Cdd:COG2768   13 CIGCG--ACVKVCPVGAISI--EDGKAVIDPEKCIGCGACIEVCPVGAikIEWEEDEEFQEKM 71
NapF COG1145
Ferredoxin [Energy production and conversion];
66-113 1.33e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 47.41  E-value: 1.33e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 446738887  66 CNHCDepVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG1145  184 CIGCG--LCVKVCPTGAIRLKDGKPQIVVDPDKCIGCGACVKVCPVGA 229
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 65-113 1.90e-06

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 43.89  E-value: 1.90e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 446738887  65 ACNHCdePVCVSGCPTGAMhkRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG2221   16 KCIGC--GLCVAVCPTGAI--SLDDGKLVIDEEKCIGCGACIRVCPTGA 60
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 66-113 6.76e-06

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 42.41  E-value: 6.76e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 446738887  66 CNHCDepVCVSGCPTGAMhKRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG1149   13 CIGCG--LCVEVCPEGAI-KLDDGGAPVVDPDLCTGCGACVGVCPTGA 57
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 92-157 7.79e-06

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 42.41  E-value: 7.79e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446738887  92 VVVDDSVCVGCRYCEMRCPYGAPQFDTQANVM---RKCDGCLdrlennlrpICVDSCPQRALDFGPVDE 157
Cdd:COG1149    6 PVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVvdpDLCTGCG---------ACVGVCPTGAITLEEREA 65
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
74-150 1.35e-05

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 44.54  E-value: 1.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  74 CVSGCPTGAMHKrkEDGLVVVDDSVCVGCRYCEMRCPYGAPQF--------------DTQANVMRKCD-GCLD------- 131
Cdd:PRK07118 147 CVAACPFDAIHI--ENGLPVVDEDKCTGCGACVKACPRNVIELipksarvfvacnskDKGKAVKKVCEvGCIGcgkcvka 224

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 446738887 132 ------RLENNLRPI----------CVDSCPQRAL 150
Cdd:PRK07118 225 cpagaiTMENNLAVIdqekctscgkCVEKCPTKAI 259
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 64-146 1.39e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 43.40  E-value: 1.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  64 IACNHCDEpVCVSGCPTGAMHKRKED------GLVVVDDSVCV------GCRYCEMRCPYGAPQFDTQANVMR------K 125
Cdd:cd16373   53 GPCDLCCD-ACVEVCPTGALRPLDLEeqkvkmGVAVIDKDRCLawqggtDCGVCVEACPTEAIAIVLEDDVLRpvvdedK 131

                         90       100
                 ....*....|....*....|.
gi 446738887 126 CDGCldrlennlrPICVDSCP 146
Cdd:cd16373  132 CVGC---------GLCEYVCP 143
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 73-152 1.73e-05

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 42.77  E-value: 1.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  73 VCVSGCPTGAMHKRKEDGL-------VVVDDSVCVGCRYCEMRCPYGA--PQFDTQANVMR-KCDGCLdrlennlrpICV 142
Cdd:cd10549   47 ACVEVCPTGAIELTPEGKEyvpkekeAEIDEEKCIGCGLCVKVCPVDAitLEDELEIVIDKeKCIGCG---------ICA 117

                         90
                 ....*....|
gi 446738887 143 DSCPQRALDF 152
Cdd:cd10549  118 EVCPVNAIKL 127
oorD PRK09626
2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed
 66-110 1.92e-05

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed


Pssm-ID: 236597 [Multi-domain]  Cd Length: 103  Bit Score: 42.01  E-value: 1.92e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446738887  66 CNHCDepVCVSGCPTGAMHKRKEDGLV------VVDDSVCVGCRYCEMRCP 110
Cdd:PRK09626  18 CKACD--ICVSVCPAGVLAMRIDPHAVlgkmikVVHPESCIGCRECELHCP 66
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 66-113 6.77e-05

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 42.94  E-value: 6.77e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 446738887  66 CNHCDEpvCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:PRK12771 512 CFECDN--CYGACPQDAIIKLGPGRRYHFDYDKCTGCHICADVCPCGA 557
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 66-113 1.02e-04

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 39.31  E-value: 1.02e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 446738887  66 CNHCDepVCVSGCPTGAMHKRKEDG-LVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG1146   10 CIGCG--ACVEVCPVDVLELDEEGKkALVINPEECIGCGACELVCPVGA 56
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
8-113 1.38e-04

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 41.46  E-value: 1.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887   8 VDSSRCSGCKTCQVSCKdNKDLDVGPKLRRVYEY----GGGSWVKEgeswhhdtftyYLSIACNHCDepVCVSGCPTGAM 83
Cdd:PRK07118 165 VDEDKCTGCGACVKACP-RNVIELIPKSARVFVAcnskDKGKAVKK-----------VCEVGCIGCG--KCVKACPAGAI 230

                         90       100       110
                 ....*....|....*....|....*....|
gi 446738887  84 hkRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:PRK07118 231 --TMENNLAVIDQEKCTSCGKCVEKCPTKA 258
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
65-113 1.46e-04

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 41.94  E-value: 1.46e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 446738887  65 ACNHCDEpvCVSGCPTGAMhkRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG4624   92 KCKNCYP--CVRACPVKAI--KVDDGKAEIDEEKCISCGQCVAVCPFGA 136
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 61-150 1.47e-04

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 40.07  E-value: 1.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  61 YLSIACNHCDEpvCVSGCPTGAMHKRKEDG---LVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVM-----------RKC 126
Cdd:cd10549    3 YDPEKCIGCGI--CVKACPTDAIELGPNGAiarGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYvpkekeaeideEKC 80

                         90       100
                 ....*....|....*....|....
gi 446738887 127 DGCLdrlennlrpICVDSCPQRAL 150
Cdd:cd10549   81 IGCG---------LCVKVCPVDAI 95
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 66-113 1.52e-04

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 38.87  E-value: 1.52e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 446738887  66 CNHCDepVCVSGCPTGAMHKrkEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG4231   24 CTGCG--ACVKVCPADAIEE--GDGKAVIDPDLCIGCGSCVQVCPVDA 67
PRK13795 PRK13795
hypothetical protein; Provisional
 66-110 1.54e-04

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 41.90  E-value: 1.54e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 446738887  66 CNHCDepVCVSGCPTGAMHKRKEDGLVVVDDSVCVGCRYCEMRCP 110
Cdd:PRK13795 583 CVGCG--VCVGACPTGAIRIEEGKRKISVDEEKCIHCGKCTEVCP 625
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 66-113 2.40e-04

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 38.19  E-value: 2.40e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 446738887  66 CNHCDepVCVSGCPTGA--MHKRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG1143    4 CIGCG--LCVRVCPVDAitIEDGEPGKVYVIDPDKCIGCGLCVEVCPTGA 51
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 66-113 3.86e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 40.54  E-value: 3.86e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446738887  66 CNHcdepVCVSGCP---TG--AMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG1245   17 CNY----ECIKYCPvnrTGkeAIEIDEDDGKPVISEELCIGCGICVKKCPFDA 65
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
87-157 5.31e-04

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 37.40  E-value: 5.31e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446738887  87 KEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMR--KCDGCldrlennlrPICVDSCPQRALDFGPVDE 157
Cdd:COG2768    1 HSLGKPYVDEEKCIGCGACVKVCPVGAISIEDGKAVIDpeKCIGC---------GACIEVCPVGAIKIEWEED 64
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 66-113 5.75e-04

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 36.74  E-value: 5.75e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 446738887   66 CNHCDepVCVSGCPTGAM-----HKRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:pfam12838   1 CIGCG--ACVAACPVGAItldevGEKKGTKTVVIDPERCVGCGACVAVCPTGA 51
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 66-113 7.53e-04

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 39.48  E-value: 7.53e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 446738887  66 CNHCDEpvCVSGCPTGAMhKRKEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:PRK00783 171 CDECEK--CVEACPRGVL-ELKEGKLVVTDLLNCSLCKLCERACPGKA 215
NapF COG1145
Ferredoxin [Energy production and conversion];
84-154 1.13e-03

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 38.94  E-value: 1.13e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446738887  84 HKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMR----KCDGCldrlennlrPICVDSCPQRALDFGP 154
Cdd:COG1145  169 KIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDGKPQIVvdpdKCIGC---------GACVKVCPVGAISLEP 234
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 91-156 1.20e-03

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 38.52  E-value: 1.20e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446738887  91 LVVVDDSVCVGCRYCEMRCPYGAPQFDTQANVMRK--CDGCldrlennlrPICVDSCPQRALDFGPVD 156
Cdd:cd03110   58 KAFIDQEKCIRCGNCERVCKFGAILEFFQKLIVDEslCEGC---------GACVIICPRGAIYLKDRD 116
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 93-154 1.64e-03

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 36.18  E-value: 1.64e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  93 VVDDSVCVGCRYCEMRCPYGA--------PQFDTQanvmrKCDGCLdrlennlrpICVDSCPQRALDFGP 154
Cdd:COG1144   26 VVDEDKCIGCGLCWIVCPDGAirvddgkyYGIDYD-----YCKGCG---------ICAEVCPVKAIEMVP 81
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 40-113 2.10e-03

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 35.80  E-value: 2.10e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446738887  40 EYGGGSWVKEGESWHHDTftyylsiaCNHCDepVCVSGCPTGAMHKRkEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:COG1144   14 AYKTGGWRVERPVVDEDK--------CIGCG--LCWIVCPDGAIRVD-DGKYYGIDYDYCKGCGICAEVCPVKA 76
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
64-150 2.12e-03

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 38.47  E-value: 2.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446738887  64 IACNHCDEPVCVSGCPtGAMHKRKEDGLVVVDDSVCVGCRYCEMRCPYGAPQF-DTQANVMR-KCDGCldrlennlrPIC 141
Cdd:COG4624   59 CCCCRCCVAISCIQVR-GIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAIKVdDGKAEIDEeKCISC---------GQC 128


                 ....*....
gi 446738887 142 VDSCPQRAL 150
Cdd:COG4624  129 VAVCPFGAI 137
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 74-110 2.44e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 37.67  E-value: 2.44e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 446738887  74 CVSGCPTGAMHKrKEDGLVVVDDSVCVGCRYCEMRCP 110
Cdd:COG2878  145 CIKACPFDAIVG-AAKGMHTVDEDKCTGCGLCVEACP 180
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
66-113 6.46e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 37.10  E-value: 6.46e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446738887  66 CNHcdepVCVSGCPTGAMHKR-----KEDGLVVVDDSVCVGCRYCEMRCPYGA 113
Cdd:PRK13409  17 CNY----ECIKYCPVVRTGEEtieidEDDGKPVISEELCIGCGICVKKCPFDA 65
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 99-156 9.26e-03

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 33.57  E-value: 9.26e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446738887  99 CVGCRYCEMRCPYGAPQFDTQANVMR------KCDGCLdrlennlrpICVDSCPQRALDFGPVD 156
Cdd:COG1143    4 CIGCGLCVRVCPVDAITIEDGEPGKVyvidpdKCIGCG---------LCVEVCPTGAISMTPFE 58
PRK13795 PRK13795
hypothetical protein; Provisional
 99-146 9.34e-03

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 36.51  E-value: 9.34e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446738887  99 CVGCRYCEMRCPYGAPQFDTQ----ANVMRKCDGCLDrlennlrpiCVDSCP 146
Cdd:PRK13795 583 CVGCGVCVGACPTGAIRIEEGkrkiSVDEEKCIHCGK---------CTEVCP 625
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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