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Conserved domains on  [gi|446742869|ref|WP_000820125|]
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MULTISPECIES: type II secretion system minor pseudopilin GspI [Enterobacteriaceae]

Protein Classification

type II secretion system protein GspI( domain architecture ID 10494788)

type II secretion system (T2SS) protein GspI is a component of the T2SS required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
T2SSI pfam02501
Type II secretion system (T2SS), protein I; The Type II secretion system, also called ...
 38-117 2.17e-20

Type II secretion system (T2SS), protein I; The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. As members of the T2SJ family, members of the T2SI family are pseudopilins containing prepilin signal sequences.


:

Pssm-ID: 426802  Cd Length: 80  Bit Score: 78.46  E-value: 2.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446742869   38 LEEKTVAGWVAENQTALLYLMTREQRAVRQQGESDMAGSRWYWRTTPLSTGNALLQAVDIEVSLHEDFSSVIQSRRAWFS 117
Cdd:pfam02501   1 LEDRTLAQWVAENQLAELRLEPQWPAIGESSGECEQAGRRWYWRVEVVPTPDPGFRRVDVSVRADKDEARPLASLRTYVG 80
 
Name Accession Description Interval E-value
T2SSI pfam02501
Type II secretion system (T2SS), protein I; The Type II secretion system, also called ...
 38-117 2.17e-20

Type II secretion system (T2SS), protein I; The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. As members of the T2SJ family, members of the T2SI family are pseudopilins containing prepilin signal sequences.


Pssm-ID: 426802  Cd Length: 80  Bit Score: 78.46  E-value: 2.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446742869   38 LEEKTVAGWVAENQTALLYLMTREQRAVRQQGESDMAGSRWYWRTTPLSTGNALLQAVDIEVSLHEDFSSVIQSRRAWFS 117
Cdd:pfam02501   1 LEDRTLAQWVAENQLAELRLEPQWPAIGESSGECEQAGRRWYWRVEVVPTPDPGFRRVDVSVRADKDEARPLASLRTYVG 80
gspI TIGR01707
type II secretion system protein I; This model represents GspI, one of two proteins highly ...
 4-101 2.86e-15

type II secretion system protein I; This model represents GspI, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspJ. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 273767 [Multi-domain]  Cd Length: 101  Bit Score: 66.00  E-value: 2.86e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446742869    4 GFTLLEVMLALAIFALAATAVLQIASGALSNQQILEEKTVAGWVAENQTALLYLMTREQRAVRQQGESDMAGSRWYWRTT 83
Cdd:TIGR01707   1 GFTLLEVLVALAIFAAAALALISSVGGQTNAIGRLRDKTLALWIADNRLAELSLGVGPPALGRNSGKELIAGREWLWRSQ 80

                          90
                  ....*....|....*...
gi 446742869   84 PLSTGNALLQAVDIEVSL 101
Cdd:TIGR01707  81 VHSTDDPTLLRVDITVAT 98
 
Name Accession Description Interval E-value
T2SSI pfam02501
Type II secretion system (T2SS), protein I; The Type II secretion system, also called ...
 38-117 2.17e-20

Type II secretion system (T2SS), protein I; The Type II secretion system, also called Secretion-dependent pathway (SDP), is responsible for the transport of proteins across the outer membrane first exported to the periplasm by the Sec or Tat translocon in Gram-negative (diderm) bacteria. As members of the T2SJ family, members of the T2SI family are pseudopilins containing prepilin signal sequences.


Pssm-ID: 426802  Cd Length: 80  Bit Score: 78.46  E-value: 2.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446742869   38 LEEKTVAGWVAENQTALLYLMTREQRAVRQQGESDMAGSRWYWRTTPLSTGNALLQAVDIEVSLHEDFSSVIQSRRAWFS 117
Cdd:pfam02501   1 LEDRTLAQWVAENQLAELRLEPQWPAIGESSGECEQAGRRWYWRVEVVPTPDPGFRRVDVSVRADKDEARPLASLRTYVG 80
gspI TIGR01707
type II secretion system protein I; This model represents GspI, one of two proteins highly ...
 4-101 2.86e-15

type II secretion system protein I; This model represents GspI, one of two proteins highly conserved at their N-termini and described by pfam02501 but easily separable phylogenetically. The other is GspJ. Both GspI and GspJ are proteins of the type II secretion pathway, or main terminal branch of the general secretion pathway. This pathway carries proteins across the outer membrane. Note that proteins of type II secretion are cryptic in E. coli K-12 - present but not yet demonstrated to act on any target.


Pssm-ID: 273767 [Multi-domain]  Cd Length: 101  Bit Score: 66.00  E-value: 2.86e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446742869    4 GFTLLEVMLALAIFALAATAVLQIASGALSNQQILEEKTVAGWVAENQTALLYLMTREQRAVRQQGESDMAGSRWYWRTT 83
Cdd:TIGR01707   1 GFTLLEVLVALAIFAAAALALISSVGGQTNAIGRLRDKTLALWIADNRLAELSLGVGPPALGRNSGKELIAGREWLWRSQ 80

                          90
                  ....*....|....*...
gi 446742869   84 PLSTGNALLQAVDIEVSL 101
Cdd:TIGR01707  81 VHSTDDPTLLRVDITVAT 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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