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Conserved domains on  [gi|446743089|ref|WP_000820345|]
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MULTISPECIES: alpha/beta fold hydrolase [Bacillus]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 47-298 1.05e-25

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 101.62  E-value: 1.05e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  47 IRAYYftKEENKHKEPILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLGEpGMSVQTKVIENQKQQAEWLNEVIEGLGL 126
Cdd:COG0596   12 VRLHY--REAGPDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGH-GRSDKPAGGYTLDDLADDLAALLDALGL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 127 ERVHIVGVSIGGWTTMNLARYNPEHIATASLLDPVFvfaqisikmilasipasvpivpKFLREKMLsyvsggAEASDDEP 206
Cdd:COG0596   89 ERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVL----------------------AALAEPLR------RPGLAPEA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 207 IAKLIESGMRnyklktpaPDLFskEDLKNIDIPVLALIAEKSTMHnSVKAVETGKKYVKDIDIVNWKNASHAINGEFSNE 286
Cdd:COG0596  141 LAALLRALAR--------TDLR--ERLARITVPTLVIWGEKDPIV-PPALARRLAELLPNAELVVLPGAGHFPPLEQPEA 209

                        250
                 ....*....|..
gi 446743089 287 VNARILDFVEKH 298
Cdd:COG0596  210 FAAALRDFLARL 221
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 47-298 1.05e-25

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 101.62  E-value: 1.05e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  47 IRAYYftKEENKHKEPILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLGEpGMSVQTKVIENQKQQAEWLNEVIEGLGL 126
Cdd:COG0596   12 VRLHY--REAGPDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGH-GRSDKPAGGYTLDDLADDLAALLDALGL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 127 ERVHIVGVSIGGWTTMNLARYNPEHIATASLLDPVFvfaqisikmilasipasvpivpKFLREKMLsyvsggAEASDDEP 206
Cdd:COG0596   89 ERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVL----------------------AALAEPLR------RPGLAPEA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 207 IAKLIESGMRnyklktpaPDLFskEDLKNIDIPVLALIAEKSTMHnSVKAVETGKKYVKDIDIVNWKNASHAINGEFSNE 286
Cdd:COG0596  141 LAALLRALAR--------TDLR--ERLARITVPTLVIWGEKDPIV-PPALARRLAELLPNAELVVLPGAGHFPPLEQPEA 209

                        250
                 ....*....|..
gi 446743089 287 VNARILDFVEKH 298
Cdd:COG0596  210 FAAALRDFLARL 221
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 61-161 2.89e-12

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 66.51  E-value: 2.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  61 EPILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLGEpGMSVQTKVIENQKQQAEWLNEVIEGLGLERVHIVGVSIGGWT 140
Cdd:PRK14875 132 TPVVLIHGFGGDLNNWLFNHAALAAGRPVIALDLPGH-GASSKAVGAGSLDELAAAVLAFLDALGIERAHLVGHSMGGAV 210

                         90       100
                 ....*....|....*....|.
gi 446743089 141 TMNLARYNPEHIATASLLDPV 161
Cdd:PRK14875 211 ALRLAARAPQRVASLTLIAPA 231
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 62-259 1.08e-10

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 60.60  E-value: 1.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089   62 PILLLPGRGASTPMWVPNLEGLREKR-PVYTIDLLGePGMSVQTKVIEN--QKQQAEWLNEVIEGLGLERVHIVGVSIGG 138
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGfRVIALDLRG-FGKSSRPKAQDDyrTDDLAEDLEYILEALGLEKVNLVGHSMGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  139 WTTMNLARYNPEHIATASLLDPVFVFAQISIKMILAsipasVPIVPKFLREkmlsyvsggaEASDDEPIAKLIESGMRNY 218
Cdd:pfam00561  81 LIALAYAAKYPDRVKALVLLGALDPPHELDEADRFI-----LALFPGFFDG----------FVADFAPNPLGRLVAKLLA 145

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 446743089  219 KLKTPApDLFSKEDLKNIDIPVLALIAEKSTMHNSVKAVET 259
Cdd:pfam00561 146 LLLLRL-RLLKALPLLNKRFPSGDYALAKSLVTGALLFIET 185
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 47-298 1.05e-25

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 101.62  E-value: 1.05e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  47 IRAYYftKEENKHKEPILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLGEpGMSVQTKVIENQKQQAEWLNEVIEGLGL 126
Cdd:COG0596   12 VRLHY--REAGPDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGH-GRSDKPAGGYTLDDLADDLAALLDALGL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 127 ERVHIVGVSIGGWTTMNLARYNPEHIATASLLDPVFvfaqisikmilasipasvpivpKFLREKMLsyvsggAEASDDEP 206
Cdd:COG0596   89 ERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVL----------------------AALAEPLR------RPGLAPEA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 207 IAKLIESGMRnyklktpaPDLFskEDLKNIDIPVLALIAEKSTMHnSVKAVETGKKYVKDIDIVNWKNASHAINGEFSNE 286
Cdd:COG0596  141 LAALLRALAR--------TDLR--ERLARITVPTLVIWGEKDPIV-PPALARRLAELLPNAELVVLPGAGHFPPLEQPEA 209

                        250
                 ....*....|..
gi 446743089 287 VNARILDFVEKH 298
Cdd:COG0596  210 FAAALRDFLARL 221
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 61-161 2.89e-12

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 66.51  E-value: 2.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  61 EPILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLGEpGMSVQTKVIENQKQQAEWLNEVIEGLGLERVHIVGVSIGGWT 140
Cdd:PRK14875 132 TPVVLIHGFGGDLNNWLFNHAALAAGRPVIALDLPGH-GASSKAVGAGSLDELAAAVLAFLDALGIERAHLVGHSMGGAV 210

                         90       100
                 ....*....|....*....|.
gi 446743089 141 TMNLARYNPEHIATASLLDPV 161
Cdd:PRK14875 211 ALRLAARAPQRVASLTLIAPA 231
PLN02578 PLN02578
hydrolase
 62-295 4.36e-11

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 62.94  E-value: 4.36e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  62 PILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLGEpGMSvQTKVIEN-----QKQQAEWLNEVIEglglERVHIVGVSI 136
Cdd:PLN02578  88 PIVLIHGFGASAFHWRYNIPELAKKYKVYALDLLGF-GWS-DKALIEYdamvwRDQVADFVKEVVK----EPAVLVGNSL 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 137 GGWTTMNLARYNPEHIATASLLDPVFVFAQISIKMIlASIPASVPIVPKF----LREKMLSYVSGGAEASDDEPiaKLIE 212
Cdd:PLN02578 162 GGFTALSTAVGYPELVAGVALLNSAGQFGSESREKE-EAIVVEETVLTRFvvkpLKEWFQRVVLGFLFWQAKQP--SRIE 238

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 213 SGMRN-YKLKT------------PAPD--------------LFSKED------LKNIDIPVLALIAEKSTMHNSVKAvET 259
Cdd:PLN02578 239 SVLKSvYKDKSnvddylvesitePAADpnagevyyrlmsrfLFNQSRytldslLSKLSCPLLLLWGDLDPWVGPAKA-EK 317

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 446743089 260 GKKYVKDIDIVNWKnASHAINGEFSNEVNARILDFV 295
Cdd:PLN02578 318 IKAFYPDTTLVNLQ-AGHCPHDEVPEQVNKALLEWL 352
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 62-259 1.08e-10

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 60.60  E-value: 1.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089   62 PILLLPGRGASTPMWVPNLEGLREKR-PVYTIDLLGePGMSVQTKVIEN--QKQQAEWLNEVIEGLGLERVHIVGVSIGG 138
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGfRVIALDLRG-FGKSSRPKAQDDyrTDDLAEDLEYILEALGLEKVNLVGHSMGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  139 WTTMNLARYNPEHIATASLLDPVFVFAQISIKMILAsipasVPIVPKFLREkmlsyvsggaEASDDEPIAKLIESGMRNY 218
Cdd:pfam00561  81 LIALAYAAKYPDRVKALVLLGALDPPHELDEADRFI-----LALFPGFFDG----------FVADFAPNPLGRLVAKLLA 145

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 446743089  219 KLKTPApDLFSKEDLKNIDIPVLALIAEKSTMHNSVKAVET 259
Cdd:pfam00561 146 LLLLRL-RLLKALPLLNKRFPSGDYALAKSLVTGALLFIET 185
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
115-300 1.60e-10

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 59.96  E-value: 1.60e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 115 EWLNEVIEGL-----GLERVHIVGVSIGGWTTMNLARYNPEhIATASLLDPVFVFAQISIKMIlasipasvPIVPKFLRE 189
Cdd:COG1647   67 DWLEDVEEAYeilkaGYDKVIVIGLSMGGLLALLLAARYPD-VAGLVLLSPALKIDDPSAPLL--------PLLKYLARS 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 190 KMlsyvsggAEASDDEpiakLIESGMRNYKlKTPAPDLFS--------KEDLKNIDIPVLALIAEK------STMHNSVK 255
Cdd:COG1647  138 LR-------GIGSDIE----DPEVAEYAYD-RTPLRALAElqrlirevRRDLPKITAPTLIIQSRKdevvppESARYIYE 205

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446743089 256 AVETgkkyvKDIDIVNWKNASHAI-NGEFSNEVNARILDFVEKHSN 300
Cdd:COG1647  206 RLGS-----PDKELVWLEDSGHVItLDKDREEVAEEILDFLERLAA 246
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
40-297 1.63e-07

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 51.16  E-value: 1.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  40 IKTKYGTIRAYYFTKEENKHKEPILLLPGRGASTPMWVPNLEGLREKR-PVYTIDLLG---EPGMSVQTKVIENQKQQAE 115
Cdd:COG2267    8 LPTRDGLRLRGRRWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAGyAVLAFDLRGhgrSDGPRGHVDSFDDYVDDLR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 116 WLNEVIEGLGLERVHIVGVSIGGWTTMNLARYNPEHIAtaslldpvfvfaqisiKMILASipasvpivPKFLREKmLSYV 195
Cdd:COG2267   88 AALDALRARPGLPVVLLGHSMGGLIALLYAARYPDRVA----------------GLVLLA--------PAYRADP-LLGP 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 196 SGGAEAsddepiakliesgmrnyklktpapDLFSKEDLKNIDIPVLALIAEKSTMhNSVKAVE-TGKKYVKDIDIVNWKN 274
Cdd:COG2267  143 SARWLR------------------------ALRLAEALARIDVPVLVLHGGADRV-VPPEAARrLAARLSPDVELVLLPG 197

                        250       260
                 ....*....|....*....|....
gi 446743089 275 ASHAI-NGEFSNEVNARILDFVEK 297
Cdd:COG2267  198 ARHELlNEPAREEVLAAILAWLER 221
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 58-147 9.52e-07

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 46.36  E-value: 9.52e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  58 KHKEPILLLPGRGASTPMWVPNLEGLREK-RPVYTIDLLgepgmSVQTKVIENQKQQAEWLNEVIEGLGLERVHIVGVSI 136
Cdd:COG1075    3 ATRYPVVLVHGLGGSAASWAPLAPRLRAAgYPVYALNYP-----STNGSIEDSAEQLAAFVDAVLAATGAEKVDLVGHSM 77

                         90
                 ....*....|.
gi 446743089 137 GGWttmnLARY 147
Cdd:COG1075   78 GGL----VARY 84
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
40-298 1.73e-06

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 48.09  E-value: 1.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  40 IKTKYG-TIRAYYFTKEENKhKEPILLLP--GRGASTPMWVPNLEGLREKR-PVYTIDLLGEpGMSVQTKVIENQKQQAE 115
Cdd:COG1506    2 FKSADGtTLPGWLYLPADGK-KYPVVVYVhgGPGSRDDSFLPLAQALASRGyAVLAPDYRGY-GESAGDWGGDEVDDVLA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 116 WLNEVIE--GLGLERVHIVGVSIGGWTTMNLARYNPEHIATASLLDPVfvfaqisikmilASIPASVPIVPKFLREKMLS 193
Cdd:COG1506   80 AIDYLAArpYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGV------------SDLRSYYGTTREYTERLMGG 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 194 YVSGGAEASDDEPIAkliesgmrnyklktpapdlfskeDLKNIDIPVLALIAEK---STMHNSVKAVETGKKYVKDIDIV 270
Cdd:COG1506  148 PWEDPEAYAARSPLA-----------------------YADKLKTPLLLIHGEAddrVPPEQAERLYEALKKAGKPVELL 204

                        250       260
                 ....*....|....*....|....*...
gi 446743089 271 NWKNASHAINGEFSNEVNARILDFVEKH 298
Cdd:COG1506  205 VYPGEGHGFSGAGAPDYLERILDFLDRH 232
PLN02824 PLN02824
hydrolase, alpha/beta fold family protein
 61-298 6.50e-05

hydrolase, alpha/beta fold family protein


Pssm-ID: 178419 [Multi-domain]  Cd Length: 294  Bit Score: 43.57  E-value: 6.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  61 EPILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLG-----EPG-MSVQTKVIENQKQQAEWLNEVIEGLGLERVHIVGV 134
Cdd:PLN02824  30 PALVLVHGFGGNADHWRKNTPVLAKSHRVYAIDLLGygysdKPNpRSAPPNSFYTFETWGEQLNDFCSDVVGDPAFVICN 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 135 SIGGWTTMNLARYNPEHIATASLLDpvfvfaqISIKMI-LASIPASV-PIVPKF---LRE------------------KM 191
Cdd:PLN02824 110 SVGGVVGLQAAVDAPELVRGVMLIN-------ISLRGLhIKKQPWLGrPFIKAFqnlLREtavgkaffksvatpetvkNI 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089 192 LSYVSGGAEASDDEPIAKLIESGmrnykLKTPAPDLF-----------SKEDLKNIDIPVLALIAEKSTMHNsvkaVETG 260
Cdd:PLN02824 183 LCQCYHDDSAVTDELVEAILRPG-----LEPGAVDVFldfisysggplPEELLPAVKCPVLIAWGEKDPWEP----VELG 253

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 446743089 261 KKYVK---DIDIVNWKNASHAINGEFSNEVNARILDFVEKH 298
Cdd:PLN02824 254 RAYANfdaVEDFIVLPGVGHCPQDEAPELVNPLIESFVARH 294
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 63-279 7.33e-05

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 43.23  E-value: 7.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089   63 ILLLPGRGAStpmwVPNLEGLREKR-PVYTIDLLGEPGMSVQTKVIENQKQQAEWLNEVIeglGLERVHIVGVSIGGWTT 141
Cdd:pfam12697   1 VVLVHGAGLS----AAPLAALLAAGvAVLAPDLPGHGSSSPPPLDLADLADLAALLDELG---AARPVVLVGHSLGGAVA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  142 MNLARYNPEHiatASLLDPVFVFaqisIKMILASIPASVPIVPKFLREKMLSYVSGGAEASDDEPIAKLIESGMRNYKLK 221
Cdd:pfam12697  74 LAAAAAALVV---GVLVAPLAAP----PGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPADAEWAAALARLAAL 146

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446743089  222 TPAPDLFSKEDLKNIDIPVLALIAEKSTMHnsvKAVETGKKYVKDIDIVNWKNASHAI 279
Cdd:pfam12697 147 LAALALLPLAAWRDLPVPVLVLAEEDRLVP---ELAQRLLAALAGARLVVLPGAGHLP 201
PLN02679 PLN02679
hydrolase, alpha/beta fold family protein
 45-96 4.11e-04

hydrolase, alpha/beta fold family protein


Pssm-ID: 178283 [Multi-domain]  Cd Length: 360  Bit Score: 41.36  E-value: 4.11e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446743089  45 GTIRAYYFTK---EENKHKEPILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLG 96
Cdd:PLN02679  70 GEYSINYLVKgspEVTSSGPPVLLVHGFGASIPHWRRNIGVLAKNYTVYAIDLLG 124
PLN02894 PLN02894
hydrolase, alpha/beta fold family protein
 52-160 1.57e-03

hydrolase, alpha/beta fold family protein


Pssm-ID: 215484 [Multi-domain]  Cd Length: 402  Bit Score: 39.89  E-value: 1.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446743089  52 FTKEENKhkEPILLLPGRGASTPMWVPNLEGLREKRPVYTIDLLGEPGMSVQTKVIENQKQQAEWLNEVIE----GLGLE 127
Cdd:PLN02894  99 FDSKEDA--PTLVMVHGYGASQGFFFRNFDALASRFRVIAIDQLGWGGSSRPDFTCKSTEETEAWFIDSFEewrkAKNLS 176

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446743089 128 RVHIVGVSIGGWTTMNLARYNPEHIATASLLDP 160
Cdd:PLN02894 177 NFILLGHSFGGYVAAKYALKHPEHVQHLILVGP 209
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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