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Conserved domains on  [gi|446750063|ref|WP_000827319|]
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MULTISPECIES: Rne/Rng family ribonuclease [Acinetobacter]

Protein Classification

ribonuclease E domain-containing protein( domain architecture ID 1001066)

ribonuclease E domain-containing protein similar to ribonuclease E (RNase E), a principal factor in RNA turnover and processing that helps to exercise fine control of gene expression in bacteria

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
CafA COG1530
Ribonuclease G or E [Translation, ribosomal structure and biogenesis];
2-482 0e+00

Ribonuclease G or E [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 441139 [Multi-domain]  Cd Length: 490  Bit Score: 741.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    2 KRMLINATHAEeVRVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFQAD 81
Cdd:COG1530     1 KEILINATPQE-TRVALVEGGRLVELDIERPGREQLVGNIYKGKVTRVLPGLQAAFVDIGLERHGFLHVKDISPEYFSLG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   82 PRQTS---NIRELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNpKGGGISRQISGSV-REELKEILASLN 157
Cdd:COG1530    80 KEDSGkrpNIQDVLKEGQEVLVQVVKEPRGTKGARLTTFISLAGRYLVLMPNN-RHVGVSRRIEGEEeRERLKELLSELK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  158 VPRGMSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNE 237
Cdd:COG1530   159 VPEGMGLIVRTAAEGASEEELQWDLDYLLKLWEAIQEAAKSAKAPFLIYQELDLIIRALRDYFRPDIGEILVDSREAYEK 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  238 AYNFVKAVMPRQLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETAL 317
Cdd:COG1530   239 AKDFISLVMPDLADRVKLYTGERPLFDRYQIESQIESALERRVWLKSGGYLVIDQTEALTTIDVNSGRFTGGRNIEETAF 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  318 NTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEAT 397
Cdd:COG1530   319 KTNLEAADEIARQLRLRDLGGIIVIDFIDMEDEEHQREVENRLKEALKKDRARTQIGGISRFGLVEMTRQRLRPSLGESL 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  398 GYVCPRCHGTGMVRDLRSLSLSIMRKVEEIALRERHGEVQVEVPVEIAAFLLNEKRHSLVYLEQTSGVRVTVLPHPHLET 477
Cdd:COG1530   399 CEPCPRCEGRGTIKSVETVALEILREIEREARKENTREVLVQAPPEVAAYLLNEKRQELAELEKRYGVSIKLIPNPSLET 478

                  ....*
gi 446750063  478 PHYEI 482
Cdd:COG1530   479 EQYDI 483
rne super family cl35953
ribonuclease E; Reviewed
1-1043 0e+00

ribonuclease E; Reviewed


The actual alignment was detected with superfamily member PRK10811:

Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 652.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    1 MKRMLINATHAEEVRVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFQA 80
Cdd:PRK10811    1 MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   81 D--PRQTSNIRELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNPKGGGISRQISGSVREELKEILASLNV 158
Cdd:PRK10811   81 NysAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  159 PRGMSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNEA 238
Cdd:PRK10811  161 PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  239 YNFVKAV-MPRQLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETAL 317
Cdd:PRK10811  241 RQHIAALgRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAF 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  318 NTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEAT 397
Cdd:PRK10811  321 NTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESS 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  398 GYVCPRCHGTGMVRDLRSLSLSIMRKVEEIALRERHGEVQVEVPVEIAAFLLNEKRHSLVYLE-QTSGVRVTVLPHPHLE 476
Cdd:PRK10811  401 HHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIEtRQGGVRCVIVPNDQMQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  477 TPHYeiaynpdgfapsSYERteaTRSSEK--ELGYESSEWHLEEAdhghahvtATASTHAAAQKKAnhATQPV----AQP 550
Cdd:PRK10811  481 TPHY------------SVLR---VRKGEEtpTLSYMLPKLHEEAM--------ALPSEEEFAERKR--PEQPAlatfAMP 535
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  551 SAQKAASPcawlenlfvQKQAQTVDQSRSAQNAAAAIEQmvnTGAVSR------GQFGQvavpavaevapvqsnnayiSQ 624
Cdd:PRK10811  536 DVPPAPTP---------AEPAAPVVAAAPKAAAATPPAQ---PGLLSRffgalkALFSG-------------------GE 584
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  625 SPVKQDVREHVEKDDKSQQQ-----RQNNKKRKHKEQREQHHQSHEQQHQVHEEVVQLSRQEQRELKRQQKRQQQQDQQH 699
Cdd:PRK10811  585 ETKPQEQPAPKAEAKPERQQdrrkpRQNNRRDRNERRDTRDNRTRREGRENREENRRNRRQAQQQTAETRESQQAEVTEK 664
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  700 QNNDVQHTENavPRRDRnnQQRPNRPNRHRDPSVLNENQNTPVVVDEKQ--IKVDVIDAPKHDVMNTALIInvdQGQSEI 777
Cdd:PRK10811  665 ARTQDEQQQA--PRRER--QRRRNDEKRQAQQEAKALNVEEQSVQETEQeeRVQQVQPRRKQRQLNQKVRI---EQSVAE 737
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  778 VALTPERRHVERVETTSTEVAQEPT-----PAPVVAEKAAVVETKEEAQPSQEAAQPQIKRASndPR------MRRRQQR 846
Cdd:PRK10811  738 EAVAPVVEETVAAEPVVQEVPAPRTelvkvPLPVVAQTAPEQDEENNAENRDNNGMPRRSRRS--PRhlrvsgQRRRRYR 815
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  847 EAK----------HAkAATPSIAPSQ------IPTLAQHTIGSLIRHVYGEDCTVLIEQFGLVPtfnralqkfAEQYAST 910
Cdd:PRK10811  816 DERyptqspmpltVA-CASPEMASGKvwirypVVRPQDVQVEEQREAEEVQVQPVVAEVPVAAA---------VEPVVSA 885
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  911 LVVEVTAETEEKKPVTRDAELPSHKPAEEAEPAPVLPLTPPQAPAPRVANDPrerrrLAKLAAEQAfEQVKQQHSAQEEV 990
Cdd:PRK10811  886 PVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVA-----VAQEVAEHA-EPVVEPQDETADI 959
                        1050      1060      1070      1080      1090
                  ....*....|....*....|....*....|....*....|....*....|...
gi 446750063  991 ATPAPVAEETVAAPTAETQATVEPAQqplelNQSTEVVQPEAAPAEEKATEET 1043
Cdd:PRK10811  960 EEAAETAEVVVAEPEVVAQPAAPVVA-----EVAAEVETVTAVEPEVAPAQVP 1007
 
Name Accession Description Interval E-value
CafA COG1530
Ribonuclease G or E [Translation, ribosomal structure and biogenesis];
2-482 0e+00

Ribonuclease G or E [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441139 [Multi-domain]  Cd Length: 490  Bit Score: 741.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    2 KRMLINATHAEeVRVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFQAD 81
Cdd:COG1530     1 KEILINATPQE-TRVALVEGGRLVELDIERPGREQLVGNIYKGKVTRVLPGLQAAFVDIGLERHGFLHVKDISPEYFSLG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   82 PRQTS---NIRELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNpKGGGISRQISGSV-REELKEILASLN 157
Cdd:COG1530    80 KEDSGkrpNIQDVLKEGQEVLVQVVKEPRGTKGARLTTFISLAGRYLVLMPNN-RHVGVSRRIEGEEeRERLKELLSELK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  158 VPRGMSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNE 237
Cdd:COG1530   159 VPEGMGLIVRTAAEGASEEELQWDLDYLLKLWEAIQEAAKSAKAPFLIYQELDLIIRALRDYFRPDIGEILVDSREAYEK 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  238 AYNFVKAVMPRQLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETAL 317
Cdd:COG1530   239 AKDFISLVMPDLADRVKLYTGERPLFDRYQIESQIESALERRVWLKSGGYLVIDQTEALTTIDVNSGRFTGGRNIEETAF 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  318 NTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEAT 397
Cdd:COG1530   319 KTNLEAADEIARQLRLRDLGGIIVIDFIDMEDEEHQREVENRLKEALKKDRARTQIGGISRFGLVEMTRQRLRPSLGESL 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  398 GYVCPRCHGTGMVRDLRSLSLSIMRKVEEIALRERHGEVQVEVPVEIAAFLLNEKRHSLVYLEQTSGVRVTVLPHPHLET 477
Cdd:COG1530   399 CEPCPRCEGRGTIKSVETVALEILREIEREARKENTREVLVQAPPEVAAYLLNEKRQELAELEKRYGVSIKLIPNPSLET 478

                  ....*
gi 446750063  478 PHYEI 482
Cdd:COG1530   479 EQYDI 483
rne PRK10811
ribonuclease E; Reviewed
1-1043 0e+00

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 652.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    1 MKRMLINATHAEEVRVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFQA 80
Cdd:PRK10811    1 MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   81 D--PRQTSNIRELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNPKGGGISRQISGSVREELKEILASLNV 158
Cdd:PRK10811   81 NysAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  159 PRGMSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNEA 238
Cdd:PRK10811  161 PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  239 YNFVKAV-MPRQLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETAL 317
Cdd:PRK10811  241 RQHIAALgRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAF 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  318 NTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEAT 397
Cdd:PRK10811  321 NTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESS 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  398 GYVCPRCHGTGMVRDLRSLSLSIMRKVEEIALRERHGEVQVEVPVEIAAFLLNEKRHSLVYLE-QTSGVRVTVLPHPHLE 476
Cdd:PRK10811  401 HHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIEtRQGGVRCVIVPNDQMQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  477 TPHYeiaynpdgfapsSYERteaTRSSEK--ELGYESSEWHLEEAdhghahvtATASTHAAAQKKAnhATQPV----AQP 550
Cdd:PRK10811  481 TPHY------------SVLR---VRKGEEtpTLSYMLPKLHEEAM--------ALPSEEEFAERKR--PEQPAlatfAMP 535
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  551 SAQKAASPcawlenlfvQKQAQTVDQSRSAQNAAAAIEQmvnTGAVSR------GQFGQvavpavaevapvqsnnayiSQ 624
Cdd:PRK10811  536 DVPPAPTP---------AEPAAPVVAAAPKAAAATPPAQ---PGLLSRffgalkALFSG-------------------GE 584
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  625 SPVKQDVREHVEKDDKSQQQ-----RQNNKKRKHKEQREQHHQSHEQQHQVHEEVVQLSRQEQRELKRQQKRQQQQDQQH 699
Cdd:PRK10811  585 ETKPQEQPAPKAEAKPERQQdrrkpRQNNRRDRNERRDTRDNRTRREGRENREENRRNRRQAQQQTAETRESQQAEVTEK 664
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  700 QNNDVQHTENavPRRDRnnQQRPNRPNRHRDPSVLNENQNTPVVVDEKQ--IKVDVIDAPKHDVMNTALIInvdQGQSEI 777
Cdd:PRK10811  665 ARTQDEQQQA--PRRER--QRRRNDEKRQAQQEAKALNVEEQSVQETEQeeRVQQVQPRRKQRQLNQKVRI---EQSVAE 737
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  778 VALTPERRHVERVETTSTEVAQEPT-----PAPVVAEKAAVVETKEEAQPSQEAAQPQIKRASndPR------MRRRQQR 846
Cdd:PRK10811  738 EAVAPVVEETVAAEPVVQEVPAPRTelvkvPLPVVAQTAPEQDEENNAENRDNNGMPRRSRRS--PRhlrvsgQRRRRYR 815
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  847 EAK----------HAkAATPSIAPSQ------IPTLAQHTIGSLIRHVYGEDCTVLIEQFGLVPtfnralqkfAEQYAST 910
Cdd:PRK10811  816 DERyptqspmpltVA-CASPEMASGKvwirypVVRPQDVQVEEQREAEEVQVQPVVAEVPVAAA---------VEPVVSA 885
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  911 LVVEVTAETEEKKPVTRDAELPSHKPAEEAEPAPVLPLTPPQAPAPRVANDPrerrrLAKLAAEQAfEQVKQQHSAQEEV 990
Cdd:PRK10811  886 PVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVA-----VAQEVAEHA-EPVVEPQDETADI 959
                        1050      1060      1070      1080      1090
                  ....*....|....*....|....*....|....*....|....*....|...
gi 446750063  991 ATPAPVAEETVAAPTAETQATVEPAQqplelNQSTEVVQPEAAPAEEKATEET 1043
Cdd:PRK10811  960 EEAAETAEVVVAEPEVVAQPAAPVVA-----EVAAEVETVTAVEPEVAPAQVP 1007
RNaseEG TIGR00757
ribonuclease, Rne/Rng family; This model describes ribonuclease G (formerly CafA, cytoplasmic ...
15-422 1.17e-177

ribonuclease, Rne/Rng family; This model describes ribonuclease G (formerly CafA, cytoplasmic axial filament protein A), the N-terminal domain of ribonuclease E in which ribonuclease activity resides, and related proteins. In E. coli, both RNase E and RNase G have been shown to play a role in the maturation of the 5' end of 16S RNA. The C-terminal half of RNase E (excluded from the seed alignment for this model) lacks ribonuclease activity but participates in mRNA degradation by organizing the degradosome. [Transcription, Degradation of RNA]


Pssm-ID: 273254 [Multi-domain]  Cd Length: 414  Bit Score: 526.12  E-value: 1.17e-177
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    15 RVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFQADPRQTS-----NIR 89
Cdd:TIGR00757    2 RVALVEGGRLFDLIIERPKSRQLKGNIYKGRVTRILPSLQAAFVDIGLEKNGFLHASDIGPNYECLAPAEAKreagpSIS 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    90 ELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNPkGGGISRQI-SGSVREELKEILASLNVPRGMSVIVRT 168
Cdd:TIGR00757   82 ELLRPGQSVLVQVVKEPRGNKGARLTTDISLPGRYLVLMPNNS-HVGVSRRIeSGEERERLKKLLRSEELPEGMGLIIRT 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   169 AGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNEAYNFVKAVMPR 248
Cdd:TIGR00757  161 AAEGASEEALIKDLEFLLRKWEKIKEKAQKRPAPCLIYGEPDIIKRVIRDYLDTDVKEILIDSKEIYEEAKEFIQLYAPE 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   249 QLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETALNTNLEAAEEIA 328
Cdd:TIGR00757  241 LVSKLKLYRGSDPLFEGFQIEKQIDKATQRKVWLPSGGYIVIDQTEALTTIDVNSGRFTGGGNLEETALNTNLEAAKEIA 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   329 RQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEATGYVCPRCHGTG 408
Cdd:TIGR00757  321 RQLRLRNLGGIIIIDFIDMKSEKNQRRVLERLKEALRRDRARIQISGISEFGLVEMTRKRLRESLMEVLGTVCPHCSGTG 400
                          410
                   ....*....|....
gi 446750063   409 MVRDLRSLSLSIMR 422
Cdd:TIGR00757  401 IVKTSESVLLEIER 414
RNase_E_G pfam10150
Ribonuclease E/G family; Ribonuclease E and Ribonuclease G are related enzymes that cleave a ...
120-387 3.85e-124

Ribonuclease E/G family; Ribonuclease E and Ribonuclease G are related enzymes that cleave a wide variety of RNAs.


Pssm-ID: 462965  Cd Length: 267  Bit Score: 380.97  E-value: 3.85e-124
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   120 LAGRYLVLMPNNpKGGGISRQISG-SVREELKEILASLNvPRGMSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASS 198
Cdd:pfam10150    1 LPGRYLVLMPFG-KIVGVSRKIEDeEERERLKEILESLK-PEGMGVIVRTAAEGASEEELQADLEYLLKLWEEILKKAKK 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   199 GPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNEAYNFVKAVMPRQLDKLKTYTLNEPLFAHFGIESQIQTAYER 278
Cdd:pfam10150   79 AKAPSLLYEELDLILRVLRDLLNDDIDEIIVDDEEVYEEIKEFLEEIAPDLKKRVELYEGERPLFDLYGIEKQIEKALSR 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   279 EVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETALNTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEA 358
Cdd:pfam10150  159 KVWLKSGGYLVIDQTEALTVIDVNSGKFTGKKNLEETALKTNLEAAKEIARQLRLRNLGGIIVIDFIDMKDEENREKVLE 238
                          250       260
                   ....*....|....*....|....*....
gi 446750063   359 KLREATQSDRARIQFGQLSRFGLMEMSRQ 387
Cdd:pfam10150  239 ALKEALKKDRAKTQVLGITKLGLVEMTRK 267
PRK11712 PRK11712
ribonuclease G; Provisional
4-473 2.83e-97

ribonuclease G; Provisional


Pssm-ID: 183285 [Multi-domain]  Cd Length: 489  Bit Score: 317.72  E-value: 2.83e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    4 MLINATHAEeVRVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIA-NSYFQADP 82
Cdd:PRK11712    5 LLVNVTPSE-TRVALIEGGILQEIHIEREAKRGIVGNIYKGRVSRVLPGMQAAFVDIGLDKAAFLHASDIVpHTECVAGE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   83 RQTS----NIRELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNPKGGgISRQI-SGSVREELKEILASLN 157
Cdd:PRK11712   84 EQKQfvvrDISELVRQGQDIMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVG-VSQRIeSEEERERLKKIVAPYC 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  158 VPRGmSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNE 237
Cdd:PRK11712  163 DEQG-GFIIRTAAEGVGEEELAQDAAFLKRLWTKVMERKKRYQTRYQLYGELALAQRVLRDFVGAELDRIRVDSRLTYEE 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  238 AYNFVKAVMPRQLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTrGH-DVEETA 316
Cdd:PRK11712  242 LKEFTSEYIPEMTDKLEHYSGRQPIFDLYDVENEIQRALERKVELKSGGYLIIDQTEAMTTVDINTGAFV-GHrNLEETI 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  317 LNTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEA 396
Cdd:PRK11712  321 FNTNIEATQAIARQLRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTNINGFSQLGLVEMTRKRTRESLEHV 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  397 TGYVCPRCHGTGMVRDLRSLSLSIMRkveEIaLRERHG----EVQVEVPVEIAAFLLNEKRHSLVYLEQTSGVRVTVLPH 472
Cdd:PRK11712  401 LCGECPTCHGRGTVKTVETVCYEIMR---EI-VRVHHAydsdRFLVYASPAVAEALKGEESHALAELEIFVGKQVKVQIE 476

                  .
gi 446750063  473 P 473
Cdd:PRK11712  477 P 477
S1_RNase_E cd04453
S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential ...
32-123 2.22e-29

S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and the maturation of tRNA, 10Sa RNA and the M1 precursor of RNase P. RNase E associates with PNPase (3' to 5' exonuclease), Rhl B (DEAD-box RNA helicase) and enolase (glycolytic enzyme) to form the RNA degradosome. RNase E tends to cut mRNA within single-stranded regions that are rich in A/U nucleotides. The N-terminal region of RNase E contains the catalytic site. Within the conserved N-terminal domain of RNAse E and RNase G, there is an S1-like subdomain, which is an ancient single-stranded RNA-binding domain. S1 domain is an RNA-binding module originally identified in the ribosomal protein S1. The S1 domain is required for RNA cleavage by RNase E. RNase G is paralogous to RNase E with an N-terminal catalytic domain that is highly homologous to that of RNase E. RNase G not only shares sequence similarity with RNase E, but also functionally overlaps with RNase E. In Escherichia coli, RNase G is involved in the maturation of the 5' end of the 16S rRNA. RNase G plays a secondary role in mRNA decay.


Pssm-ID: 239900 [Multi-domain]  Cd Length: 88  Bit Score: 112.30  E-value: 2.22e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   32 RTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFqadpRQTSNIRELITEGTELLVQVEKEERGNKG 111
Cdd:cd04453     1 PNREPIVGNIYLGRVKKIVPGLQAAFVDIGLGKNGFLHLSDILPAYF----KKHKKIAKLLKEGQEILVQVVKEPIGTKG 76
                          90
                  ....*....|..
gi 446750063  112 AALSTFISLAGR 123
Cdd:cd04453    77 PRLTTNISLPGR 88
S1 smart00316
Ribosomal protein S1-like RNA-binding domain;
37-116 1.54e-06

Ribosomal protein S1-like RNA-binding domain;


Pssm-ID: 197648 [Multi-domain]  Cd Length: 72  Bit Score: 46.83  E-value: 1.54e-06
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063     37 KKSNIYKGHVTRVEPSleAVFVEYGAGRQGFLSMREIANSYfqadprqTSNIRELITEGTELLVQVEKEERGNKGAALST 116
Cdd:smart00316    1 EVGDVVEGTVTEITPG--GAFVDLGNGVEGLIPISELSDKR-------VKDPEEVLKVGDEVKVKVLSVDEEKGRIILSL 71
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
921-1035 6.12e-03

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 38.18  E-value: 6.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   921 EKKPVTRDAELPSHKPAEEAEPAPVLPLTPPQAPAPRVANDPRERRRLAKLAAEQAFEQVKQQHSAQEEVATPAPVAEet 1000
Cdd:pfam05104   40 KKKEEKPNGKLPESEQADESEEEPREFKTPDEAPSAALEPEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAK-- 117
                           90       100       110
                   ....*....|....*....|....*....|....*
gi 446750063  1001 vaaptaetqatVEPAQQPlELNQSTEVVQPEAAPA 1035
Cdd:pfam05104  118 -----------VEPAETP-EAVQPKPALEKEEPPA 140
 
Name Accession Description Interval E-value
CafA COG1530
Ribonuclease G or E [Translation, ribosomal structure and biogenesis];
2-482 0e+00

Ribonuclease G or E [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441139 [Multi-domain]  Cd Length: 490  Bit Score: 741.58  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    2 KRMLINATHAEeVRVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFQAD 81
Cdd:COG1530     1 KEILINATPQE-TRVALVEGGRLVELDIERPGREQLVGNIYKGKVTRVLPGLQAAFVDIGLERHGFLHVKDISPEYFSLG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   82 PRQTS---NIRELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNpKGGGISRQISGSV-REELKEILASLN 157
Cdd:COG1530    80 KEDSGkrpNIQDVLKEGQEVLVQVVKEPRGTKGARLTTFISLAGRYLVLMPNN-RHVGVSRRIEGEEeRERLKELLSELK 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  158 VPRGMSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNE 237
Cdd:COG1530   159 VPEGMGLIVRTAAEGASEEELQWDLDYLLKLWEAIQEAAKSAKAPFLIYQELDLIIRALRDYFRPDIGEILVDSREAYEK 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  238 AYNFVKAVMPRQLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETAL 317
Cdd:COG1530   239 AKDFISLVMPDLADRVKLYTGERPLFDRYQIESQIESALERRVWLKSGGYLVIDQTEALTTIDVNSGRFTGGRNIEETAF 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  318 NTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEAT 397
Cdd:COG1530   319 KTNLEAADEIARQLRLRDLGGIIVIDFIDMEDEEHQREVENRLKEALKKDRARTQIGGISRFGLVEMTRQRLRPSLGESL 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  398 GYVCPRCHGTGMVRDLRSLSLSIMRKVEEIALRERHGEVQVEVPVEIAAFLLNEKRHSLVYLEQTSGVRVTVLPHPHLET 477
Cdd:COG1530   399 CEPCPRCEGRGTIKSVETVALEILREIEREARKENTREVLVQAPPEVAAYLLNEKRQELAELEKRYGVSIKLIPNPSLET 478

                  ....*
gi 446750063  478 PHYEI 482
Cdd:COG1530   479 EQYDI 483
rne PRK10811
ribonuclease E; Reviewed
1-1043 0e+00

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 652.88  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    1 MKRMLINATHAEEVRVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFQA 80
Cdd:PRK10811    1 MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   81 D--PRQTSNIRELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNPKGGGISRQISGSVREELKEILASLNV 158
Cdd:PRK10811   81 NysAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  159 PRGMSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNEA 238
Cdd:PRK10811  161 PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  239 YNFVKAV-MPRQLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETAL 317
Cdd:PRK10811  241 RQHIAALgRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAF 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  318 NTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEAT 397
Cdd:PRK10811  321 NTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESS 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  398 GYVCPRCHGTGMVRDLRSLSLSIMRKVEEIALRERHGEVQVEVPVEIAAFLLNEKRHSLVYLE-QTSGVRVTVLPHPHLE 476
Cdd:PRK10811  401 HHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIEtRQGGVRCVIVPNDQMQ 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  477 TPHYeiaynpdgfapsSYERteaTRSSEK--ELGYESSEWHLEEAdhghahvtATASTHAAAQKKAnhATQPV----AQP 550
Cdd:PRK10811  481 TPHY------------SVLR---VRKGEEtpTLSYMLPKLHEEAM--------ALPSEEEFAERKR--PEQPAlatfAMP 535
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  551 SAQKAASPcawlenlfvQKQAQTVDQSRSAQNAAAAIEQmvnTGAVSR------GQFGQvavpavaevapvqsnnayiSQ 624
Cdd:PRK10811  536 DVPPAPTP---------AEPAAPVVAAAPKAAAATPPAQ---PGLLSRffgalkALFSG-------------------GE 584
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  625 SPVKQDVREHVEKDDKSQQQ-----RQNNKKRKHKEQREQHHQSHEQQHQVHEEVVQLSRQEQRELKRQQKRQQQQDQQH 699
Cdd:PRK10811  585 ETKPQEQPAPKAEAKPERQQdrrkpRQNNRRDRNERRDTRDNRTRREGRENREENRRNRRQAQQQTAETRESQQAEVTEK 664
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  700 QNNDVQHTENavPRRDRnnQQRPNRPNRHRDPSVLNENQNTPVVVDEKQ--IKVDVIDAPKHDVMNTALIInvdQGQSEI 777
Cdd:PRK10811  665 ARTQDEQQQA--PRRER--QRRRNDEKRQAQQEAKALNVEEQSVQETEQeeRVQQVQPRRKQRQLNQKVRI---EQSVAE 737
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  778 VALTPERRHVERVETTSTEVAQEPT-----PAPVVAEKAAVVETKEEAQPSQEAAQPQIKRASndPR------MRRRQQR 846
Cdd:PRK10811  738 EAVAPVVEETVAAEPVVQEVPAPRTelvkvPLPVVAQTAPEQDEENNAENRDNNGMPRRSRRS--PRhlrvsgQRRRRYR 815
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  847 EAK----------HAkAATPSIAPSQ------IPTLAQHTIGSLIRHVYGEDCTVLIEQFGLVPtfnralqkfAEQYAST 910
Cdd:PRK10811  816 DERyptqspmpltVA-CASPEMASGKvwirypVVRPQDVQVEEQREAEEVQVQPVVAEVPVAAA---------VEPVVSA 885
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  911 LVVEVTAETEEKKPVTRDAELPSHKPAEEAEPAPVLPLTPPQAPAPRVANDPrerrrLAKLAAEQAfEQVKQQHSAQEEV 990
Cdd:PRK10811  886 PVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVA-----VAQEVAEHA-EPVVEPQDETADI 959
                        1050      1060      1070      1080      1090
                  ....*....|....*....|....*....|....*....|....*....|...
gi 446750063  991 ATPAPVAEETVAAPTAETQATVEPAQqplelNQSTEVVQPEAAPAEEKATEET 1043
Cdd:PRK10811  960 EEAAETAEVVVAEPEVVAQPAAPVVA-----EVAAEVETVTAVEPEVAPAQVP 1007
RNaseEG TIGR00757
ribonuclease, Rne/Rng family; This model describes ribonuclease G (formerly CafA, cytoplasmic ...
15-422 1.17e-177

ribonuclease, Rne/Rng family; This model describes ribonuclease G (formerly CafA, cytoplasmic axial filament protein A), the N-terminal domain of ribonuclease E in which ribonuclease activity resides, and related proteins. In E. coli, both RNase E and RNase G have been shown to play a role in the maturation of the 5' end of 16S RNA. The C-terminal half of RNase E (excluded from the seed alignment for this model) lacks ribonuclease activity but participates in mRNA degradation by organizing the degradosome. [Transcription, Degradation of RNA]


Pssm-ID: 273254 [Multi-domain]  Cd Length: 414  Bit Score: 526.12  E-value: 1.17e-177
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    15 RVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFQADPRQTS-----NIR 89
Cdd:TIGR00757    2 RVALVEGGRLFDLIIERPKSRQLKGNIYKGRVTRILPSLQAAFVDIGLEKNGFLHASDIGPNYECLAPAEAKreagpSIS 81
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    90 ELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNPkGGGISRQI-SGSVREELKEILASLNVPRGMSVIVRT 168
Cdd:TIGR00757   82 ELLRPGQSVLVQVVKEPRGNKGARLTTDISLPGRYLVLMPNNS-HVGVSRRIeSGEERERLKKLLRSEELPEGMGLIIRT 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   169 AGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNEAYNFVKAVMPR 248
Cdd:TIGR00757  161 AAEGASEEALIKDLEFLLRKWEKIKEKAQKRPAPCLIYGEPDIIKRVIRDYLDTDVKEILIDSKEIYEEAKEFIQLYAPE 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   249 QLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETALNTNLEAAEEIA 328
Cdd:TIGR00757  241 LVSKLKLYRGSDPLFEGFQIEKQIDKATQRKVWLPSGGYIVIDQTEALTTIDVNSGRFTGGGNLEETALNTNLEAAKEIA 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   329 RQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEATGYVCPRCHGTG 408
Cdd:TIGR00757  321 RQLRLRNLGGIIIIDFIDMKSEKNQRRVLERLKEALRRDRARIQISGISEFGLVEMTRKRLRESLMEVLGTVCPHCSGTG 400
                          410
                   ....*....|....
gi 446750063   409 MVRDLRSLSLSIMR 422
Cdd:TIGR00757  401 IVKTSESVLLEIER 414
RNase_E_G pfam10150
Ribonuclease E/G family; Ribonuclease E and Ribonuclease G are related enzymes that cleave a ...
120-387 3.85e-124

Ribonuclease E/G family; Ribonuclease E and Ribonuclease G are related enzymes that cleave a wide variety of RNAs.


Pssm-ID: 462965  Cd Length: 267  Bit Score: 380.97  E-value: 3.85e-124
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   120 LAGRYLVLMPNNpKGGGISRQISG-SVREELKEILASLNvPRGMSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASS 198
Cdd:pfam10150    1 LPGRYLVLMPFG-KIVGVSRKIEDeEERERLKEILESLK-PEGMGVIVRTAAEGASEEELQADLEYLLKLWEEILKKAKK 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   199 GPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNEAYNFVKAVMPRQLDKLKTYTLNEPLFAHFGIESQIQTAYER 278
Cdd:pfam10150   79 AKAPSLLYEELDLILRVLRDLLNDDIDEIIVDDEEVYEEIKEFLEEIAPDLKKRVELYEGERPLFDLYGIEKQIEKALSR 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   279 EVKLPSGGSIVIDQTEALVSIDINSAKSTRGHDVEETALNTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEA 358
Cdd:pfam10150  159 KVWLKSGGYLVIDQTEALTVIDVNSGKFTGKKNLEETALKTNLEAAKEIARQLRLRNLGGIIVIDFIDMKDEENREKVLE 238
                          250       260
                   ....*....|....*....|....*....
gi 446750063   359 KLREATQSDRARIQFGQLSRFGLMEMSRQ 387
Cdd:pfam10150  239 ALKEALKKDRAKTQVLGITKLGLVEMTRK 267
PRK11712 PRK11712
ribonuclease G; Provisional
4-473 2.83e-97

ribonuclease G; Provisional


Pssm-ID: 183285 [Multi-domain]  Cd Length: 489  Bit Score: 317.72  E-value: 2.83e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    4 MLINATHAEeVRVALITGNRLYDFDLENRTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIA-NSYFQADP 82
Cdd:PRK11712    5 LLVNVTPSE-TRVALIEGGILQEIHIEREAKRGIVGNIYKGRVSRVLPGMQAAFVDIGLDKAAFLHASDIVpHTECVAGE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   83 RQTS----NIRELITEGTELLVQVEKEERGNKGAALSTFISLAGRYLVLMPNNPKGGgISRQI-SGSVREELKEILASLN 157
Cdd:PRK11712   84 EQKQfvvrDISELVRQGQDIMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVG-VSQRIeSEEERERLKKIVAPYC 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  158 VPRGmSVIVRTAGIGRTQEELQLDLQHLLDLWAQIQGTASSGPSPMLVHQEAGVVTRAIRDYLRDDVAEILIDSEQAYNE 237
Cdd:PRK11712  163 DEQG-GFIIRTAAEGVGEEELAQDAAFLKRLWTKVMERKKRYQTRYQLYGELALAQRVLRDFVGAELDRIRVDSRLTYEE 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  238 AYNFVKAVMPRQLDKLKTYTLNEPLFAHFGIESQIQTAYEREVKLPSGGSIVIDQTEALVSIDINSAKSTrGH-DVEETA 316
Cdd:PRK11712  242 LKEFTSEYIPEMTDKLEHYSGRQPIFDLYDVENEIQRALERKVELKSGGYLIIDQTEAMTTVDINTGAFV-GHrNLEETI 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  317 LNTNLEAAEEIARQLRLRDIGGLVVIDFIDMTKERNQRMVEAKLREATQSDRARIQFGQLSRFGLMEMSRQRLRPSLEEA 396
Cdd:PRK11712  321 FNTNIEATQAIARQLRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTNINGFSQLGLVEMTRKRTRESLEHV 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  397 TGYVCPRCHGTGMVRDLRSLSLSIMRkveEIaLRERHG----EVQVEVPVEIAAFLLNEKRHSLVYLEQTSGVRVTVLPH 472
Cdd:PRK11712  401 LCGECPTCHGRGTVKTVETVCYEIMR---EI-VRVHHAydsdRFLVYASPAVAEALKGEESHALAELEIFVGKQVKVQIE 476

                  .
gi 446750063  473 P 473
Cdd:PRK11712  477 P 477
S1_RNase_E cd04453
S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential ...
32-123 2.22e-29

S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and the maturation of tRNA, 10Sa RNA and the M1 precursor of RNase P. RNase E associates with PNPase (3' to 5' exonuclease), Rhl B (DEAD-box RNA helicase) and enolase (glycolytic enzyme) to form the RNA degradosome. RNase E tends to cut mRNA within single-stranded regions that are rich in A/U nucleotides. The N-terminal region of RNase E contains the catalytic site. Within the conserved N-terminal domain of RNAse E and RNase G, there is an S1-like subdomain, which is an ancient single-stranded RNA-binding domain. S1 domain is an RNA-binding module originally identified in the ribosomal protein S1. The S1 domain is required for RNA cleavage by RNase E. RNase G is paralogous to RNase E with an N-terminal catalytic domain that is highly homologous to that of RNase E. RNase G not only shares sequence similarity with RNase E, but also functionally overlaps with RNase E. In Escherichia coli, RNase G is involved in the maturation of the 5' end of the 16S rRNA. RNase G plays a secondary role in mRNA decay.


Pssm-ID: 239900 [Multi-domain]  Cd Length: 88  Bit Score: 112.30  E-value: 2.22e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   32 RTREQKKSNIYKGHVTRVEPSLEAVFVEYGAGRQGFLSMREIANSYFqadpRQTSNIRELITEGTELLVQVEKEERGNKG 111
Cdd:cd04453     1 PNREPIVGNIYLGRVKKIVPGLQAAFVDIGLGKNGFLHLSDILPAYF----KKHKKIAKLLKEGQEILVQVVKEPIGTKG 76
                          90
                  ....*....|..
gi 446750063  112 AALSTFISLAGR 123
Cdd:cd04453    77 PRLTTNISLPGR 88
S1 smart00316
Ribosomal protein S1-like RNA-binding domain;
37-116 1.54e-06

Ribosomal protein S1-like RNA-binding domain;


Pssm-ID: 197648 [Multi-domain]  Cd Length: 72  Bit Score: 46.83  E-value: 1.54e-06
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063     37 KKSNIYKGHVTRVEPSleAVFVEYGAGRQGFLSMREIANSYfqadprqTSNIRELITEGTELLVQVEKEERGNKGAALST 116
Cdd:smart00316    1 EVGDVVEGTVTEITPG--GAFVDLGNGVEGLIPISELSDKR-------VKDPEEVLKVGDEVKVKVLSVDEEKGRIILSL 71
S1 pfam00575
S1 RNA binding domain; The S1 domain occurs in a wide range of RNA associated proteins. It is ...
37-116 3.00e-05

S1 RNA binding domain; The S1 domain occurs in a wide range of RNA associated proteins. It is structurally similar to cold shock protein which binds nucleic acids. The S1 domain has an OB-fold structure.


Pssm-ID: 425760 [Multi-domain]  Cd Length: 72  Bit Score: 43.04  E-value: 3.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063    37 KKSNIYKGHVTRVEPslEAVFVEYGAGRQGFLSMREIANsyfqadpRQTSNIRELITEGTELLVQVEKEERGNKGAALST 116
Cdd:pfam00575    2 EKGDVVEGEVTRVTK--GGAFVDLGNGVEGFIPISELSD-------DHVEDPDEVIKVGDEVKVKVLKVDKDRRRIILSI 72
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
908-1042 1.46e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.02  E-value: 1.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  908 ASTLVVEVTAETEEKKPVTRDAELPSHKPAEEAEPAPVLPLTPPQAPAPRVANDPRErrrlAKLAAEQAFEQVKQQHSAQ 987
Cdd:PRK12323  375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPE----ALAAARQASARGPGGAPAP 450
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 446750063  988 EEVATPAPVAEETVAAPTAETQATVEPAQQPLELNQSTEVVQPEAAPAEEKATEE 1042
Cdd:PRK12323  451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPE 505
PHA03247 PHA03247
large tegument protein UL36; Provisional
801-1014 9.65e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 9.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  801 PTPAPVVAEKAAVVETKEEAQPSQEAAQPQIKRASNDPRMRRRQQREAKHAKAATPSIAPSqiPTLAQHTIGSLirhvyg 880
Cdd:PHA03247 2624 PDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPR--RRAARPTVGSL------ 2695
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  881 edcTVLIEQFGLVPTFNRALQKFAEQYASTLVVEVTAETEEKKPVTRDAELPSHKPA----EEAEPAPVLPLTPPQAPAP 956
Cdd:PHA03247 2696 ---TSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAtpggPARPARPPTTAGPPAPAPP 2772
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446750063  957 RVANDPrERRRLAKLAAEQAFEQVKQQHSAQEEVATPAPVAEETVAAPTAETQATVEP 1014
Cdd:PHA03247 2773 AAPAAG-PPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
S1_like cd00164
S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of ...
42-115 1.04e-03

S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. Both domains are members of the Oligonucleotide/oligosaccharide Binding (OB) fold.


Pssm-ID: 238094 [Multi-domain]  Cd Length: 65  Bit Score: 38.52  E-value: 1.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446750063   42 YKGHVTRVEPslEAVFVEYGAGRQGFLSMREIANSYFQadprqtsNIRELITEGTELLVQVEKEERGNKGAALS 115
Cdd:cd00164     1 VTGKVVSITK--FGVFVELEDGVEGLVHISELSDKFVK-------DPSEVFKVGDEVEVKVLEVDPEKGRISLS 65
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
932-1043 4.33e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 4.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  932 PSHKPAEEAEPAPvlplTPPQAPAPRVANDPRERRRLAKLAAEQAFEQvkQQHSAQEEVATPAPVAEETVAAPTAETQAT 1011
Cdd:PRK07764  396 AAAPSAAAAAPAA----APAPAAAAPAAAAAPAPAAAPQPAPAPAPAP--APPSPAGNAPAGGAPSPPPAAAPSAQPAPA 469
                          90       100       110
                  ....*....|....*....|....*....|..
gi 446750063 1012 VEPAQQPLELNQSTEVVQPEAAPAEEKATEET 1043
Cdd:PRK07764  470 PAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPA 501
Rib_recp_KP_reg pfam05104
Ribosome receptor lysine/proline rich region; This highly conserved region is found towards ...
921-1035 6.12e-03

Ribosome receptor lysine/proline rich region; This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.


Pssm-ID: 461548 [Multi-domain]  Cd Length: 140  Bit Score: 38.18  E-value: 6.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063   921 EKKPVTRDAELPSHKPAEEAEPAPVLPLTPPQAPAPRVANDPRERRRLAKLAAEQAFEQVKQQHSAQEEVATPAPVAEet 1000
Cdd:pfam05104   40 KKKEEKPNGKLPESEQADESEEEPREFKTPDEAPSAALEPEPVPTPVPAPVEPEPAPPSESPAPSPKEKKKKEKKSAK-- 117
                           90       100       110
                   ....*....|....*....|....*....|....*
gi 446750063  1001 vaaptaetqatVEPAQQPlELNQSTEVVQPEAAPA 1035
Cdd:pfam05104  118 -----------VEPAETP-EAVQPKPALEKEEPPA 140
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
924-1035 6.73e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 6.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  924 PVTRDAELPSHKPAEEAEPAPVLPLTPPQAPAPRVANDPRERRRLAKLAAEQAFEqvkQQHSAQEEVATPAPVAEETVAA 1003
Cdd:PRK07764  403 AAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPP---PAAAPSAQPAPAPAAAPEPTAA 479
                          90       100       110
                  ....*....|....*....|....*....|..
gi 446750063 1004 PTAETQATVEPAQQPlelnqstEVVQPEAAPA 1035
Cdd:PRK07764  480 PAPAPPAAPAPAAAP-------AAPAAPAAPA 504
PRK10263 PRK10263
DNA translocase FtsK; Provisional
756-1014 7.10e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.45  E-value: 7.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  756 APKHDVMNTALIINVDQG-QSEIVALTPerrhVERVETTSTEVAQEPTPAPVVAEKAAVVETKEEaqPSQEAAQPQIKRA 834
Cdd:PRK10263  335 APVEPVTQTPPVASVDVPpAQPTVAWQP----VPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNE--PLQQPVQPQQPYY 408
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  835 SNDPRMRRRQQREAKHAkaATPSIAPSQIPTLAQHTIGSLIRHVYGEdctvliEQFGLVPTFnralqkfaeQYASTLVVE 914
Cdd:PRK10263  409 APAAEQPAQQPYYAPAP--EQPAQQPYYAPAPEQPVAGNAWQAEEQQ------STFAPQSTY---------QTEQTYQQP 471
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  915 VTAETEEKKPvtrdaelPSHKPAEEAEPAPVLPLTPPQAPaPRVANDPRERRRLAKLAAEQAFEQVKQQHSAQEEVATPA 994
Cdd:PRK10263  472 AAQEPLYQQP-------QPVEQQPVVEPEPVVEETKPARP-PLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSS 543
                         250       260
                  ....*....|....*....|
gi 446750063  995 PVAEETVAAPTAETQATVEP 1014
Cdd:PRK10263  544 LKAPSVAAVPPVEAAAAVSP 563
PRK10263 PRK10263
DNA translocase FtsK; Provisional
800-1039 7.28e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.45  E-value: 7.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  800 EPTPAPVVAEKAAVVETKEEAQPSQEAAQ-PQIKRASNDPRMRRRQQREAKHAKAATPSIAPsQIPTLAQHTIGSLIRHV 878
Cdd:PRK10263  314 APITEPVAVAAAATTATQSWAAPVEPVTQtPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAP-APEGYPQQSQYAQPAVQ 392
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  879 YGEDCTVLIEQFGLVPTFNRALQKFAEQYASTLVVEVTAETEEKKPVTRDAELPSHKPAEEAEPAPVLPLTPPQAPAPRV 958
Cdd:PRK10263  393 YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPA 472
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  959 ANDPRErrrlaklaaeqafeqVKQQHSAQEEVATPAPVAEETVAAP--------------------TAETQATVEPAQQP 1018
Cdd:PRK10263  473 AQEPLY---------------QQPQPVEQQPVVEPEPVVEETKPARpplyyfeeveekrarereqlAAWYQPIPEPVKEP 537
                         250       260
                  ....*....|....*....|.
gi 446750063 1019 LELNQSTEVVQPEAAPAEEKA 1039
Cdd:PRK10263  538 EPIKSSLKAPSVAAVPPVEAA 558
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
932-1042 9.09e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 40.23  E-value: 9.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446750063  932 PSHKPAEEAEPAPVLPLTPPQAPAPRVANDPRERRRLAKLAAEQAFEQVKQQHSAQEEVATPAPVAEETVAAPTaETQAT 1011
Cdd:PRK07994  383 ATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPVNSAL-ERLAS 461
                          90       100       110
                  ....*....|....*....|....*....|..
gi 446750063 1012 VEPAQQPLELN-QSTEVVQPEAAPAEEKATEE 1042
Cdd:PRK07994  462 VRPAPSALEKApAKKEAYRWKATNPVEVKKEP 493
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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