|
Name |
Accession |
Description |
Interval |
E-value |
| pabB |
PRK15465 |
aminodeoxychorismate synthase component 1; |
1-453 |
0e+00 |
|
aminodeoxychorismate synthase component 1;
Pssm-ID: 185362 [Multi-domain] Cd Length: 453 Bit Score: 972.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 1 MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPL 80
Cdd:PRK15465 1 MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVADPICTLTTFGKETVVSESEKRTTTTDDPL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 81 QVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV 160
Cdd:PRK15465 81 QVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRQTVSLLSHNDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 161 NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP 240
Cdd:PRK15465 161 NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 241 FSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVA 320
Cdd:PRK15465 241 FSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 321 GSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC 400
Cdd:PRK15465 321 GSVKVPELFVVEPFPAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 446777763 401 GNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLEK 453
Cdd:PRK15465 401 GNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNRILRQLEK 453
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
6-452 |
0e+00 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 607.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 6 PAVITLPWRQDAAEfYFSRLSHLPWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQ 85
Cdd:COG0147 4 PVYRELLALETPVS-LFLKLADGPYAFLLESAEGGEKWGRYSFIGADPLATLTVRGGRVTIEGGGEVEPSEGDPLDALRA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 86 VLDRadIRPTHNEDLP-FQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTvsllshndvnarr 164
Cdd:COG0147 83 LLAR--FRLPPLPGLPpFTGGLVGYFGYDLVRYFERLPDLAPDDLGLPDAALGLYDRLLVFDHLKGT------------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 165 awlesqqfspqedftltsdwQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAF 244
Cdd:COG0147 148 --------------------RSNFTREEYLAAVERAKEYIRAGDIFQVVLSQRFSAPFEGDPLALYRALRRINPSPYMFY 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 245 LRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVK 324
Cdd:COG0147 208 LRFGDFAIVGSSPERLVRVEDGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPGSVK 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 325 VPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMD 404
Cdd:COG0147 288 VPELMVVERYSHVMHLVSTVTGRLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMD 367
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 446777763 405 TSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLE 452
Cdd:COG0147 368 LAIAIRTAVVKDGRAYVQAGAGIVADSDPEAEYQETLNKARALLRALE 415
|
|
| pabB |
TIGR00553 |
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, ... |
106-447 |
0e+00 |
|
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, aminodeoxychorismate synthase, component I (PabB), were designated para-aminobenzoate synthase component I until it was recognized that PabC, a lyase, completes the pathway of PABA synthesis. This family is closely related to anthranilate synthase component I (trpE), and both act on chorismate. The clade of PabB enzymes represented by this model includes sequences from Gram-positive and alpha and gamma Proteobacteria as well as Chlorobium, Nostoc, Fusobacterium and Arabidopsis. A closely related clade of fungal PabB enzymes is identified by TIGR01823, while another bacterial clade of potential PabB enzymes is more closely related to TrpE (TIGR01824). [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid]
Pssm-ID: 273133 Cd Length: 328 Bit Score: 520.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 106 ALGLFGYDLGrrfeslpeiaeqdivlPDMAVGIYDWALIVDH-QRHTVSLLSHNDVNAR-RAWLESQQFSPQEDFTLTSD 183
Cdd:TIGR00553 1 LVGYLSYEAG----------------PDAAFEPYDAALLADHrRTPLLRFLVFERVEAQpRAAVEAEDDAPADRQAPTSD 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 184 WQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILC 263
Cdd:TIGR00553 65 IQSEMTRAEYGEAIDQLQDYIRAGDCYQANLTQQFHATWDGDPLAAFRKLRRRQPAPFSAFLDLGDGAILSLSPELFFSI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 264 DNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVST 343
Cdd:TIGR00553 145 DGSEIETRPIKGTLPRGADPQEDRAQASALAESAKDRAENLMIVDLLRNDLGRIAEVGSVKVPELFVVETYPTVHQLVST 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 344 ITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSA 423
Cdd:TIGR00553 225 ITARLREDLTLSDLFRALFPGGSITGAPKVRAMEIIDELEPQPRGVYCGAIGYLSPEGDMDFNVAIRTLTLDGGRAVYGV 304
|
330 340
....*....|....*....|....
gi 446777763 424 GGGIVADSQEEAEYQETFDKVNKI 447
Cdd:TIGR00553 305 GGGIVADSDPEAEYRECLLKAAPL 328
|
|
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
191-443 |
8.38e-122 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 354.94 E-value: 8.38e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 191 EQYGEKFRQVQEYLHSGDCYQVNLAQRF--HATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEI 268
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLtlPLAGDIDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVDGGRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 269 QTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQL 348
Cdd:pfam00425 81 ITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVSTISGRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 349 PEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIV 428
Cdd:pfam00425 161 KPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIV 240
|
250
....*....|....*
gi 446777763 429 ADSQEEAEYQETFDK 443
Cdd:pfam00425 241 ADSDPEAEWEETEAK 255
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pabB |
PRK15465 |
aminodeoxychorismate synthase component 1; |
1-453 |
0e+00 |
|
aminodeoxychorismate synthase component 1;
Pssm-ID: 185362 [Multi-domain] Cd Length: 453 Bit Score: 972.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 1 MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPL 80
Cdd:PRK15465 1 MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVADPICTLTTFGKETVVSESEKRTTTTDDPL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 81 QVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV 160
Cdd:PRK15465 81 QVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRQTVSLLSHNDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 161 NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP 240
Cdd:PRK15465 161 NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 241 FSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVA 320
Cdd:PRK15465 241 FSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 321 GSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC 400
Cdd:PRK15465 321 GSVKVPELFVVEPFPAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 446777763 401 GNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLEK 453
Cdd:PRK15465 401 GNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNRILRQLEK 453
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
6-452 |
0e+00 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 607.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 6 PAVITLPWRQDAAEfYFSRLSHLPWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQ 85
Cdd:COG0147 4 PVYRELLALETPVS-LFLKLADGPYAFLLESAEGGEKWGRYSFIGADPLATLTVRGGRVTIEGGGEVEPSEGDPLDALRA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 86 VLDRadIRPTHNEDLP-FQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTvsllshndvnarr 164
Cdd:COG0147 83 LLAR--FRLPPLPGLPpFTGGLVGYFGYDLVRYFERLPDLAPDDLGLPDAALGLYDRLLVFDHLKGT------------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 165 awlesqqfspqedftltsdwQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAF 244
Cdd:COG0147 148 --------------------RSNFTREEYLAAVERAKEYIRAGDIFQVVLSQRFSAPFEGDPLALYRALRRINPSPYMFY 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 245 LRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVK 324
Cdd:COG0147 208 LRFGDFAIVGSSPERLVRVEDGRVETRPIAGTRPRGATPEEDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPGSVK 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 325 VPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMD 404
Cdd:COG0147 288 VPELMVVERYSHVMHLVSTVTGRLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMD 367
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 446777763 405 TSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLE 452
Cdd:COG0147 368 LAIAIRTAVVKDGRAYVQAGAGIVADSDPEAEYQETLNKARALLRALE 415
|
|
| pabB |
TIGR00553 |
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, ... |
106-447 |
0e+00 |
|
aminodeoxychorismate synthase, component I, bacterial clade; Members of this family, aminodeoxychorismate synthase, component I (PabB), were designated para-aminobenzoate synthase component I until it was recognized that PabC, a lyase, completes the pathway of PABA synthesis. This family is closely related to anthranilate synthase component I (trpE), and both act on chorismate. The clade of PabB enzymes represented by this model includes sequences from Gram-positive and alpha and gamma Proteobacteria as well as Chlorobium, Nostoc, Fusobacterium and Arabidopsis. A closely related clade of fungal PabB enzymes is identified by TIGR01823, while another bacterial clade of potential PabB enzymes is more closely related to TrpE (TIGR01824). [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid]
Pssm-ID: 273133 Cd Length: 328 Bit Score: 520.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 106 ALGLFGYDLGrrfeslpeiaeqdivlPDMAVGIYDWALIVDH-QRHTVSLLSHNDVNAR-RAWLESQQFSPQEDFTLTSD 183
Cdd:TIGR00553 1 LVGYLSYEAG----------------PDAAFEPYDAALLADHrRTPLLRFLVFERVEAQpRAAVEAEDDAPADRQAPTSD 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 184 WQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILC 263
Cdd:TIGR00553 65 IQSEMTRAEYGEAIDQLQDYIRAGDCYQANLTQQFHATWDGDPLAAFRKLRRRQPAPFSAFLDLGDGAILSLSPELFFSI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 264 DNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVST 343
Cdd:TIGR00553 145 DGSEIETRPIKGTLPRGADPQEDRAQASALAESAKDRAENLMIVDLLRNDLGRIAEVGSVKVPELFVVETYPTVHQLVST 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 344 ITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSA 423
Cdd:TIGR00553 225 ITARLREDLTLSDLFRALFPGGSITGAPKVRAMEIIDELEPQPRGVYCGAIGYLSPEGDMDFNVAIRTLTLDGGRAVYGV 304
|
330 340
....*....|....*....|....
gi 446777763 424 GGGIVADSQEEAEYQETFDKVNKI 447
Cdd:TIGR00553 305 GGGIVADSDPEAEYRECLLKAAPL 328
|
|
| PabB-clade2 |
TIGR01824 |
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely ... |
104-443 |
1.51e-127 |
|
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.
Pssm-ID: 130883 Cd Length: 355 Bit Score: 373.72 E-value: 1.51e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 104 GGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVsLLSHNDVNARRAWLESQQFSPQ-EDFTLTS 182
Cdd:TIGR01824 1 GGRLGWLAYDVARRLEGIPDLGTSDGGWPVAADFRYEAAVARDHQRQIV-ALATVPAETEGEFATSSDQLPAvAAATSLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 183 DWQSN---------MTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHA--TYSGDEWQAFLQLNQANRAPFSAFLRLEQGA 251
Cdd:TIGR01824 80 SPDVGplpvdleasIDRAAYETGVRRIKDYIRAGDVFQANLSRRLTApiAADVDPLQLFLALRAPNPAPYAIYLEEPGVD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 252 ILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVV 331
Cdd:TIGR01824 160 VASASPELFLAREGRVVQTRPIAGTRPRGATLAEDGALAAELLQHDKDRAEHVMIVDLERNDLGRVCATGTVRVPELCAV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 332 EPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRT 411
Cdd:TIGR01824 240 ESYSHVHHLVSRVTGRLREGAGLADLIRALFPGGSITGAPKVRAMEIIDELEPQPRGPYTGSVGWIDADGNADLNILIRT 319
|
330 340 350
....*....|....*....|....*....|..
gi 446777763 412 LTAINGQIYCSAGGGIVADSQEEAEYQETFDK 443
Cdd:TIGR01824 320 LEGGGAQLHFRTGAGIVADSDPAGEWDETEAK 351
|
|
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
191-443 |
8.38e-122 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 354.94 E-value: 8.38e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 191 EQYGEKFRQVQEYLHSGDCYQVNLAQRF--HATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEI 268
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLtlPLAGDIDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSVDGGRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 269 QTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQL 348
Cdd:pfam00425 81 ITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHLVSTISGRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 349 PEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIV 428
Cdd:pfam00425 161 KPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAGIV 240
|
250
....*....|....*
gi 446777763 429 ADSQEEAEYQETFDK 443
Cdd:pfam00425 241 ADSDPEAEWEETEAK 255
|
|
| trpE_most |
TIGR00564 |
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some ... |
33-452 |
4.65e-120 |
|
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. Archaeal enzymes have been excluded from this model (and are now found in TIGR01820) as have a clade of enzymes which constitute a TrpE paralog which may have PabB activity (TIGR01824). This allows the B. subtilus paralog which has been shown to have PabB activity to score below trusted to this model. This model contains sequences from gram-positive bacteria, certain proteobacteria, cyanobacteria, plants, fungi and assorted other bacteria.A second family of TrpE enzymes is modelled by TIGR00565. The breaking of the TrpE family into these diverse models allows for the separation of the models for the related enzyme, PabB. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273142 [Multi-domain] Cd Length: 454 Bit Score: 358.18 E-value: 4.65e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 33 LLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQGGALGLFGY 112
Cdd:TIGR00564 20 LLESAEPGSERGRYSFIGLNPVLTIKTEGGTEYLGADDRRSGIVGNPLDEIRDVMETFAQHSDPELPIPFTGGAVGYLGY 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 113 DLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDVNA-RRAWLESQQ-------------------- 171
Cdd:TIGR00564 100 DTVRLFEKITLPPPDPLNLPDAYLMLCDDFIIFDHVTDKLYLIHNNRTTAsRSAKAAADArlealvadlqdpllpevpvp 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 172 FSPQEDFTltsdwqSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGA 251
Cdd:TIGR00564 180 YPAALSFT------SNYEKEEYEANVAKAKEYIKAGDIFQVVLSQRFEAKTEAPPFELYRVLRIVNPSPYMYYLDFGDFQ 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 252 ILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVV 331
Cdd:TIGR00564 254 IVGSSPELLVKVTGGRITTRPIAGTRKRGATPEEDEALAEELLADEKERAEHLMLVDLGRNDIGRVCEPGSVEVPEFMKI 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 332 EPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRT 411
Cdd:TIGR00564 334 ERYSHVMHIVSTVEGRLKDGLTAIDALRATFPAGTVSGAPKIRAMELIDELEPEKRGIYGGAVGYLSFDGDMDTAIAIRT 413
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 446777763 412 LTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLE 452
Cdd:TIGR00564 414 MVVKDGKAYVQAGGGIVADSDPEAEYEETLNKARALLRAIE 454
|
|
| PRK05940 |
PRK05940 |
anthranilate synthase component I; |
22-452 |
2.68e-103 |
|
anthranilate synthase component I;
Pssm-ID: 235651 [Multi-domain] Cd Length: 463 Bit Score: 315.52 E-value: 2.68e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 22 FSRL-SHLPWAMLLHSGY---ADHPY-SRFDIVVAEPictlttfgketvvseSEKR--TTTTDDPLQVLQQVLDRADIRP 94
Cdd:PRK05940 24 FERLfGQQGIATLLESPYptpADYPPlSRYSICAGSP---------------RKPRlwTPKLGEILPFLRQLLARSLDPS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 95 THNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPdmavgIYDWA-----LIVDHQRHTVSLLSHN--DVNARRAWL 167
Cdd:PRK05940 89 ALPEHLPFTGGWLGWLGYDLAWEIERLPHLNPDPLPFP-----VAYWYepesfAILDHQEQILWLAASDpsQLDRLEQQL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 168 ESQQFS---PQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAF 244
Cdd:PRK05940 164 EQPTPEpdlPLDLRTPPSSLIFYTTQQEYEAAVRQAKKYIQAGDIFQANLSLRFQTTTSADSWQIYRRLQQINPSPFASY 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 245 LRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVK 324
Cdd:PRK05940 244 WRTPWGDVVSCSPERLVQLQGNQAQTRPIAGTRPRGKTPAEDQQLAEELLSNIKERAEHIMLVDLERNDLGRVCQWGSVE 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 325 VPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMD 404
Cdd:PRK05940 324 VDELLTIERYSHVIHLVSNVVGTLQPNRDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYGSCGYLDQRGNLD 403
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 446777763 405 TSITIRTLTAIN-----GQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLE 452
Cdd:PRK05940 404 LNILIRTLLYTPlsrglSTIWGQVGAGIVADSDPEKEWLESLQKAKAQLAALN 456
|
|
| PRK07508 |
PRK07508 |
aminodeoxychorismate synthase component I; |
69-439 |
7.78e-101 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236035 [Multi-domain] Cd Length: 378 Bit Score: 306.17 E-value: 7.78e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 69 SEKRTTTTDDPLQVLQqVLDRADIRPT--HNEDLPFQGGAL-GLFGYDLGRRFE-SLPEIAEQDIVLPDMAVGIYDWALI 144
Cdd:PRK07508 9 PAGRAVLFADPSEIIR-ARTPDEFAPAlaAMERARAAGKWLaGYLSYEAGYLLEpKLAPLMPEGRETPLLCFGVFDAPSP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 145 VDHQRHTVSllshndvnARRAWLESqqFSPQedftltsdwqsnMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSG 224
Cdd:PRK07508 88 EAPAPARPS--------ENAARLRD--PVAR------------WDFADYAQRFERLHRHIRAGDCYQANLTFPLDARWGG 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 225 DEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSE-IQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAEN 303
Cdd:PRK07508 146 DPLALFWALAARQPVGYGALVDLGGPVILSRSPELFFRVDGEGwIETHPMKGTAPRGATPAEDARLRAALLNDEKNQAEN 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 304 LMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELE 383
Cdd:PRK07508 226 RMIVDLLRNDISRISEVGSLDVPELFDIETYPTVHQMVSRVRARLLPGLGLADIFAALFPCGSITGAPKIRAMEILRELE 305
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 446777763 384 PQRRNAWCGSIGYLSFCGNMDTSITIRTLTAIN-GQIYCSAGGGIVADSQEEAEYQE 439
Cdd:PRK07508 306 PGPRDLYCGAIGWIAPDGRMRFNVAIRTLSLFPgGRAVFNVGGGIVFDSTAEAEYEE 362
|
|
| PRK09070 |
PRK09070 |
aminodeoxychorismate synthase component I; |
33-452 |
1.09e-96 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236371 [Multi-domain] Cd Length: 447 Bit Score: 297.77 E-value: 1.09e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 33 LLHSGYADHPYSRFDIVVAEPictlttfGKETVVS-ESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQGGALGLFG 111
Cdd:PRK09070 27 LLESSASGTAQGRWDVLLLAQ-------GKCLRLDpDGVTRQLLEGDFLDALDAAWQAERVPHDGESSLPFRGGWAVLLD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 112 YDLGRRFE-SLPEIAEQDIVLPDMAVGIyDWALIVDHQRHTVSLLSHNDVNARRAWLESqqfspqeDFTLTSDWQSNMTR 190
Cdd:PRK09070 100 YELAGQVEpILKLPMRTDGLPLALALRA-PAAVLRDRHSGRCVLVAEPGREHLLDQIEA-------DLAACAALPPLPVW 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 191 -------EQYGEKF----RQVQEYLHSGDCYQVNLAQRFHATYSGDEWQA--FLQLNQANRAPFSAFLRLEQGAILSLSP 257
Cdd:PRK09070 172 lapqaveEDPPERFtdgvERVLDYIRAGDVFQVNLSRAWQAQFANAVDPAalYARLRAANPAPFSGLFVAAGRAIVSSSP 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 258 ERFILCDNSEIQTRPIKGTLPRLPDpQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAV 337
Cdd:PRK09070 252 ERLVSVQGGVVQTRPIAGTRPRFAG-DDDAALIRELVGHPKERAEHVMLIDLERNDLGRICAPGSVEVDELMTVESYAHV 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 338 HHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAING 417
Cdd:PRK09070 331 HHIVSNVRGRLRDGVTPGEVIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLNILIRTAEVQGN 410
|
410 420 430
....*....|....*....|....*....|....*
gi 446777763 418 QIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLE 452
Cdd:PRK09070 411 QVRFRTGAGIVVDSDPERELDETRAKARGLLRALE 445
|
|
| PRK13571 |
PRK13571 |
anthranilate synthase component I; Provisional |
29-449 |
2.23e-96 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184152 [Multi-domain] Cd Length: 506 Bit Score: 298.86 E-value: 2.23e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 29 PWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETV-VSESEKRTTTTDDPLQVLQQVLDRadIRPTHNEDLP-FQGGA 106
Cdd:PRK13571 48 PGTFLLESAENGRSWSRWSFIGVGSPAALTVRDGEAVwLGTPPAGAPTGGDPLAALRATLEL--LATPRLPGLPpLTGGM 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 107 LGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSL----LSHNDVNARRAW-----------LESQQ 171
Cdd:PRK13571 126 VGFLGYDAVRRLERLPELAVDDLGLPEMLLLLATDLAAVDHHEGTITLianaVNWNGTDERVDAayddavarldvMTAAL 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 172 FSPQEDFTLT-----SDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLR 246
Cdd:PRK13571 206 AQPLPSTVATfsrpvPEFRAQRTVEEFGAAVEKLVEEIRAGEAFQVVPSQRFEMDTTADPLDVYRVLRVTNPSPYMYLLR 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 247 LEQGA------ILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVA 320
Cdd:PRK13571 286 VPNSDggtdfsIVGSSPEALVTVTDGRATTHPIAGTRWRGATPEEDALLEKELLADPKERAEHLMLVDLGRNDLGRVCRP 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 321 GSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC 400
Cdd:PRK13571 366 GTVRVVDFSHIERYSHVMHLVSTVTGELAEGRTALDAVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFA 445
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 446777763 401 GNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILR 449
Cdd:PRK13571 446 GDADTAIAIRTALMRDGTAYVQAGGGVVADSDPDYEDNEARNKAAAVLR 494
|
|
| PLN02445 |
PLN02445 |
anthranilate synthase component I |
45-446 |
6.07e-84 |
|
anthranilate synthase component I
Pssm-ID: 215244 [Multi-domain] Cd Length: 523 Bit Score: 267.32 E-value: 6.07e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 45 RFDIVVAEPicTLTTFGKETVVS-----ESEKRTTTTDDPLQVLQQVLDRAdiRPTHNEDLP--FQGGALGLFGYDLGRR 117
Cdd:PLN02445 58 RYSVVGAQP--AMEIVAKENKVTimdheKGTRTEEIVEDPMEIPRRISEKW--NPQLIDGLPdvFCGGWVGYFSYDTVRY 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 118 -------FESLPEiaeQDIVLPDMAVGIYDWALIVDHQR------HTVSLLSHNDVNArrAW------------------ 166
Cdd:PLN02445 134 vekkklpFSGAPE---DDRNLPDIHLGLYDDVIVFDHVEkkayviHWVRLDRYSSVEE--AYedgmkrlealvsrlqdin 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 167 ----------LESQQFSPQEDftltsdwQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQA 236
Cdd:PLN02445 209 ppklspgsvkLSTNQFGPSLE-------KSNMTSEEYKNAVLQAKEHILAGDIFQIVLSQRFERRTFADPFEVYRALRIV 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 237 NRAPFSAFLRlEQGAIL-SLSPErfILC--DNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRND 313
Cdd:PLN02445 282 NPSPYMIYLQ-ARGCILvASSPE--ILTrvKKNKIVNRPLAGTRRRGKTPEEDKALEKDLLADEKQCAEHIMLVDLGRND 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 314 IGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGS 393
Cdd:PLN02445 359 VGKVSKAGSVKVEKLMNIERYSHVMHISSTVTGELLDHLTSWDALRAALPVGTVSGAPKVRAMELIDELEVTRRGPYSGG 438
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446777763 394 IGYLSFCGNMDTSITIRTLTAINGQ------------------IYCSAGGGIVADSQEEAEYQETfdkVNK 446
Cdd:PLN02445 439 FGGVSFTGDMDIALALRTMVFPTAArydtmysykdtnsrrewvAHLQAGAGIVADSDPEDEYREC---VNK 506
|
|
| PRK05877 |
PRK05877 |
aminodeoxychorismate synthase component I; Provisional |
104-452 |
1.93e-78 |
|
aminodeoxychorismate synthase component I; Provisional
Pssm-ID: 235634 [Multi-domain] Cd Length: 405 Bit Score: 249.24 E-value: 1.93e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 104 GGALGLFGY-DLGRRfeslpeiaEQDIVLPDMAVGIYDWALIVDH--QRHTVSLLSHNDVNARRAWLESQQFSPQEDFTl 180
Cdd:PRK05877 63 GGWFGYLSYpDAGAD--------GRPPRIPEAAGGWTDHVLRRDRdgQWWYESLSGAPDPDWLASALATTRARPAPPCR- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 181 tSDWQSNmTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERF 260
Cdd:PRK05877 134 -IDWTPP-DRAAHRDGVLACLEAIAAGEVYQACVCTQFTGTVTGSPLDFFADGVARTAPARAAYLAGDWGAVASLSPELF 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 261 ILCDNSEIQTRPIKGTLPRLPDPqedskqaEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHL 340
Cdd:PRK05877 212 LRRRGSVVTSSPIKGTLPLDADP-------SALRASAKDVAENIMIVDLVRNDLGRVARTGTVTVPELLVVRPAPGVWHL 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 341 VSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLT-AINGQI 419
Cdd:PRK05877 285 VSTVSAQVPDELPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAGCELNVAIRTVEfDADGNA 364
|
330 340 350
....*....|....*....|....*....|...
gi 446777763 420 YCSAGGGIVADSQEEAEYQETFDKVNKILRQLE 452
Cdd:PRK05877 365 VLGVGGGITADSDPDAEWQECLHKAAPIVGLPA 397
|
|
| PRK13572 |
PRK13572 |
anthranilate synthase component I; Provisional |
33-452 |
3.28e-73 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 237432 [Multi-domain] Cd Length: 435 Bit Score: 236.94 E-value: 3.28e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 33 LLHSGYADHPYSRFDIVVAEPICTLTTfGKETVVSEseKRTTTTDDPLQVLQQVLDRADirpthnEDLPFQGGALGLFGY 112
Cdd:PRK13572 26 ILESAEKGQRKARYTYISANPEFMVRI-GNKTKVDG--ETISKESNPFKALKENFKITQ------SGDRFTGGFVGYIAY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 113 DlgrrfeSLPEIAEQDIVLPDMaVGIYDWALIVDHQRHTVSLLSHND-----VNARRAWLESQQFSPQEDFTLTSDWQSN 187
Cdd:PRK13572 97 D------AVHNYIGGKIEEPSV-FGYYDHVFVYDHVTRKFYFHSLNNnpeelFNAEKIVEKAKRFEIEEEDGGSEVLGCD 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 188 MTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQgAILSLSPERFILCDNSE 267
Cdd:PRK13572 170 ADREEFVEMVEKAKEYIYSGDVFQVVLSREYRLKTDLSPFQLYRNLREINPSPYMFLLEFDK-DVVGASPETMASVENNI 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 268 IQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQ 347
Cdd:PRK13572 249 LKINPIAGTAPRGKTEEEDKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRLERFFDVVKYSHVQHIESEVVGE 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 348 LPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRtLTAINGQIYCSAGGGI 427
Cdd:PRK13572 329 LKEDSTMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIR-MAEIDKVCRVRAGAGI 407
|
410 420
....*....|....*....|....*
gi 446777763 428 VADSQEEAEYQETFDKVNKILRQLE 452
Cdd:PRK13572 408 VADSVPEKEFYETERKMAAVLKALG 432
|
|
| PLN02889 |
PLN02889 |
oxo-acid-lyase/anthranilate synthase |
98-439 |
3.61e-72 |
|
oxo-acid-lyase/anthranilate synthase
Pssm-ID: 215481 [Multi-domain] Cd Length: 918 Bit Score: 244.37 E-value: 3.61e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 98 EDLPFQ--GGALGLFGYDLgrRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLS-HNDVNARRAWLE------ 168
Cdd:PLN02889 532 EGLPFDfhGGYVGYIGYDL--KVECGMASNRHKSTTPDACFFFADNVVVIDHHYDDVYILSlHEGSTATTQWLDdteqkl 609
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 169 -----------SQQFSPQEDFTLT-SDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSG-DEWQAFLQLNQ 235
Cdd:PLN02889 610 lglkasatrklEVQTSPTATFSPSkAGFLADKSREQYIKDVQKCLKYIKDGESYELCLTTQMRKRIGEiDSLGLYLHLRE 689
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 236 ANRAPFSAFLRL--EQGAILSLSPERFILCD-NSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRN 312
Cdd:PLN02889 690 KNPAPYAAWLNFsnENLCICSSSPERFLKLDrNGMLEAKPIKGTIARGSTPEEDEQLKLQLQYSEKDQAENLMIVDLLRN 769
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 313 DIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCG 392
Cdd:PLN02889 770 DLGRVCEPGSVHVPNLMDVESYTTVHTMVSTIRGKKRSNMSPVDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSG 849
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 446777763 393 SIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQE 439
Cdd:PLN02889 850 SIGFFSYNQTFDLNIVIRTVVIHEGEASIGAGGAIVALSNPEDEYEE 896
|
|
| PRK13574 |
PRK13574 |
anthranilate synthase component I; Provisional |
77-444 |
2.79e-71 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184155 [Multi-domain] Cd Length: 420 Bit Score: 231.24 E-value: 2.79e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 77 DDPLQVLQQVLDRADIrpthnEDLP--FQGGALGLFGYDLGRRFESL----PEIAEqdivLPDMAVGIYDWALIVDHQRH 150
Cdd:PRK13574 56 DDPVNILNSYLKDLKL-----VDIPglFKGGMIGYISYDAVRFWEKIrdlkPAAED----WPYAEFFIPDNIIIYDHNEG 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 151 TVSLlsHNDVNARRAWLESQQFSpqedftlTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAF 230
Cdd:PRK13574 127 KVYV--NGDLSSVGGCGDMGEFK-------ISFYDESLNKNNYEKIVSESLEYIRSGYIFQVVLSRFYRYLFSGDPLRIY 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 231 LQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLM 310
Cdd:PRK13574 198 YNLRRINPSPYMFYLKFDERYLIGSSPELLFRVQDNIVETYPIAGTRPRGSDQEEDLKLELELMNSEKDKAEHLMLVDLA 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 311 RNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAW 390
Cdd:PRK13574 278 RNDLGKVCVPGTVRVPELMYVEKYSHVQHIVSKVIGTLKKKYNALDVLKATFPAGTVSGAPKPMAMNIIETLEEYKRGPY 357
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 446777763 391 CGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKV 444
Cdd:PRK13574 358 AGAVGFISADGNAEFAIAIRTAFLNKDLLRIQAGAGIVYDSNPESEYFETEHKL 411
|
|
| PRK13564 |
PRK13564 |
anthranilate synthase component 1; |
68-443 |
4.36e-60 |
|
anthranilate synthase component 1;
Pssm-ID: 237428 [Multi-domain] Cd Length: 520 Bit Score: 204.68 E-value: 4.36e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 68 ESEKRTTTTddPLQVLQQVLDRADIRPTHNEDLpFQGGalgLFGYDLGRRFESLPEIAEQDIVlPDMAVGIYDWALIVDH 147
Cdd:PRK13564 114 EDARLKSLS--VFDALRLLQKLVNTPKEEREAL-FLGG---LFAYDLVAGFEPLPQLPAGNNC-PDYCFYLAETLLVIDH 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 148 QRHTVSLLSH---------NDVNARRAWLESQQFSPQEDFTLTS----DWQSNMTREQYGEKFRQVQEYLHSGDCYQVNL 214
Cdd:PRK13564 187 QKKSARLQASlftpdeeekQRLAARLAQLKQQLTQPAPPLPVTSvpdmEVSVNISDEEFCAVVRKLKEHIRAGDIFQVVP 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 215 AQRFhatyS---GDEWQAFLQLNQANRAPFSAFLrleQGAILSL---SPE---RFiLCDNSEIQTRPIKGTLPRLPDPQE 285
Cdd:PRK13564 267 SRRF----SlpcPSPLAAYRVLKKSNPSPYMFYM---QDEDFTLfgaSPEsalKY-DASSRQVEIYPIAGTRPRGRRADG 338
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 286 ------DSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLR 359
Cdd:PRK13564 339 sidrdlDSRIELELRTDHKELAEHLMLVDLARNDLARICQPGSRYVADLLKVDRYSHVMHLVSRVVGELRHDLDALHAYR 418
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 360 AAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQE 439
Cdd:PRK13564 419 ACMNMGTLTGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHGDLDTCIVIRSAFVENGIATVQAGAGVVLDSDPQSEADE 498
|
....
gi 446777763 440 TFDK 443
Cdd:PRK13564 499 TRNK 502
|
|
| PRK13567 |
PRK13567 |
anthranilate synthase component I; Provisional |
45-448 |
6.78e-55 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184148 [Multi-domain] Cd Length: 468 Bit Score: 189.59 E-value: 6.78e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 45 RFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDR--ADIRPTHNEDLPFQGGALGLFGYDLGRR-FESL 121
Cdd:PRK13567 38 RYSVVIFDIYGTLTLDNDVLSVSTLKESYQITERPYHYLTTKINEdyHNIQDEQLKSLPFISGYVGTCSFDLVRHeFPKL 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 122 PEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV-NARRAWLES------------QQFSPQEDF-TLTSDWQSN 187
Cdd:PRK13567 118 QSIQLEDHKQHDVRLYMVEQVYVFDHYKDELYIIATNQFsNSTKSDLENrvnksiedltkiQPFMPTQDFdFKTKEIQSN 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 188 MTREQYGEKFRQVQEYLHSGDCYQV----------NLAQRFHATysgdEWQAFLQLNQANRAPFSAFLRLEQGAILSLSP 257
Cdd:PRK13567 198 ISEERFIEMIQYFKEKITEGDMFQVvpsriykyahHASQHLNQL----SFQLYQNLKRQNPSPYMYYLNIDQPYIVGSSP 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 258 ERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAV 337
Cdd:PRK13567 274 ESFVSVKDQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSEHRMLVDLGRNDIHRVSKIGTSKITKLMVIEKYEHV 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 338 HHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAING 417
Cdd:PRK13567 354 MHIVSEVTGKINQNLSPMTVIANLLPTGTVSGAPKLRAIERIYEQYPHKRGVYSGGVGYINCNHNLDFALAIRTMMIDEQ 433
|
410 420 430
....*....|....*....|....*....|.
gi 446777763 418 QIYCSAGGGIVADSQEEAEYQETFDKVNKIL 448
Cdd:PRK13567 434 YINVEAGCGVVYDSIPEKELNETKLKAKSLL 464
|
|
| PRK07093 |
PRK07093 |
para-aminobenzoate synthase component I; Validated |
170-444 |
4.60e-46 |
|
para-aminobenzoate synthase component I; Validated
Pssm-ID: 235932 [Multi-domain] Cd Length: 323 Bit Score: 162.35 E-value: 4.60e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 170 QQFSPQEDFTLTSDWQSN-MTREQYGEKFRQVQEYLHSGDCYQVNLAQR--FHATYSgdewqaFLQLNQANRAPFSAFLr 246
Cdd:PRK07093 52 TNVPSQVRPHKPFELQKEpISFEEYQQGFELVQEEIQAGNSYLLNLTYPtpIETNLS------LEEIFQASKAKYKLLF- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 247 leQGAILSLSPERFILCDNSEIQTRPIKGTLP-RLPDPQEdskqaeKLANSAKDRAENLMIVDLMRNDIGRVAvaGSVKV 325
Cdd:PRK07093 125 --KDQFVCFSPEPFVRIEDNKISTYPMKGTIDaSLPNAEE------KLLNDEKEFAEHATIVDLLRNDLSMVA--KNVRV 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 326 PELFVVEPFPAVH----HLVSTITAQLPEQLHAS--DLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYlsF 399
Cdd:PRK07093 195 TRFRYIDKIKTNKgeilQTSSEISGTLPENWQENigDILAKLLPAGSITGAPKEKTVEIIEQAEGYERGFYTGVFGY--F 272
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 446777763 400 CG-NMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKV 444
Cdd:PRK07093 273 DGeSLDSAVMIRFIEQENDGLYFKSGGGITIDSDLKDEYNELIQKV 318
|
|
| PRK13566 |
PRK13566 |
anthranilate synthase component I; |
107-453 |
2.50e-45 |
|
anthranilate synthase component I;
Pssm-ID: 237429 [Multi-domain] Cd Length: 720 Bit Score: 167.79 E-value: 2.50e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 107 LGL---FGYDLGRRFE----SLPEIAEQ-DIVL--PDMAvgiydwaLIVDHQRHTVSLLSH----NDVN----ARRAwlE 168
Cdd:PRK13566 155 LGLygaFGYDLAFQFEpieqKLPRPDDQrDLVLylPDEI-------LVVDHYAARAWVDRYefavGGVSteglPRET--A 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 169 SQQFSPQEDFTLTSDwqsnMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLE 248
Cdd:PRK13566 226 PSPYKPTTARPGFAD----HAPGEYAALVEKAKESFRRGDLFEVVPGQTFYEPCERSPSEIFRRLKEINPSPYGFFINLG 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 249 QGAIL-SLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPE 327
Cdd:PRK13566 302 DGEYLvGASPEMFVRVEGRRVETCPISGTIKRGADAIGDAEQIRKLLNSKKDESELTMCTDVDRNDKSRVCEPGSVKVIG 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 328 LFVVEPFPAVHHLVSTITAQLPEQLHASDllraAFPGG----SITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNM 403
Cdd:PRK13566 382 RRQIEMYSRLIHTVDHVEGRLRPGFDALD----AFLTHawavTVTGAPKLWAMQFIEDHERSPRRWYGGAVGMVGFDGDM 457
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 446777763 404 DTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLEK 453
Cdd:PRK13566 458 NTGLTLRTIRIKDGVAEVRVGATLLFDSDPEAEEAETELKASALLQALRG 507
|
|
| PRK06404 |
PRK06404 |
anthranilate synthase component I; Reviewed |
180-448 |
9.00e-45 |
|
anthranilate synthase component I; Reviewed
Pssm-ID: 102361 [Multi-domain] Cd Length: 351 Bit Score: 159.65 E-value: 9.00e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 180 LTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYsgDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPER 259
Cdd:PRK06404 94 KTVKLKGNYNDISLSLKIKELIELIRAGEVLQVVISREFEANI--DFKEKLSEFINNDRSRYVFYYRFGKYRVVGSSPEN 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 260 FILCDNSEIQTRPIKGTLPrlpdpqeDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHH 339
Cdd:PRK06404 172 VFTVNGNIINVDPIAGTYD-------DKILSNELLNSEKDKLEHRMLLDLARNDLSKFADIGTLNVDKVMKIEEFSSVKH 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 340 LVSTITAQLPEQLHAsDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSfCGNMDTSITIRTLTAINGQI 419
Cdd:PRK06404 245 LVSQVTAKFSNASYR-DILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIGIIS-KGYTDMALVIRTAYSHGNGF 322
|
250 260
....*....|....*....|....*....
gi 446777763 420 YCSAGGGIVADSQEEAEYQETFDKVNKIL 448
Cdd:PRK06404 323 RVRAGAGIVKDSDPEDEVNEIYSKARSVM 351
|
|
| MenF |
COG1169 |
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ... |
185-452 |
4.03e-34 |
|
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440783 [Multi-domain] Cd Length: 353 Bit Score: 130.66 E-value: 4.03e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 185 QSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSG--DEWQAFLQLNQAN---------RAPFSAFLrleqGAil 253
Cdd:COG1169 83 RGVPDPAEWREAVAQALEAIRAGELDKVVLARALDLTLDEpiDPRALLARLRRRNpdcytfaveLGAGDGFV----GA-- 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 254 slSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVagSVKVPElfvvEP 333
Cdd:COG1169 157 --SPERLVRRRGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHALVVDSIREALAPLCS--SLDVPE----EP 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 334 F----PAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITI 409
Cdd:COG1169 229 EllrlRNVQHLATPITGTLDPGVSALDLAAALHPTPAVGGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAVAI 308
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446777763 410 RTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLE 452
Cdd:COG1169 309 RSALIDGNRARLFAGAGIVAGSDPEAEWAETEAKLRTMLRALG 351
|
|
| Anth_synt_I_N |
pfam04715 |
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) ... |
22-152 |
1.38e-28 |
|
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) catalyzes the first step in the biosynthesis of tryptophan. Component I catalyzes the formation of anthranilate using ammonia and chorismate. The catalytic site lies in the adjacent region, described in the chorismate binding enzyme family (pfam00425). This region is involved in feedback inhibition by tryptophan. This family also contains a region of Para-aminobenzoate synthase component I (EC 4.1.3.-).
Pssm-ID: 428082 [Multi-domain] Cd Length: 140 Bit Score: 109.71 E-value: 1.38e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 22 FSRLSHLPWAMLLHSgyADHPYSRFDIVVAEPICTLTTFGKETVVSESE-KRTTTTDDPLQVLQQVLDRADIRPTHNEDL 100
Cdd:pfam04715 9 YLKLAGEPHSFLLES--AEGGEGRYSFIGINPLLTIKSKNGEVSVSGPDgQELEQEDGPLDALRALLARFRIEDSPPTLP 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 446777763 101 PFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTV 152
Cdd:pfam04715 87 PFSGGLVGYLGYDLVRYIEKLPRTAPDDLNLPDARLILYEDLIVFDHQENKL 138
|
|
| PRK07054 |
PRK07054 |
isochorismate synthase; |
231-440 |
1.41e-21 |
|
isochorismate synthase;
Pssm-ID: 235920 [Multi-domain] Cd Length: 475 Bit Score: 96.76 E-value: 1.41e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 231 LQLNQANRAPFsAFLRlEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLM 310
Cdd:PRK07054 239 LRLRDPHAHLF-AFRR-GNACFLGATPERLVRVAAGDLHTHALAGTIARGADPAEDARLGAALMASAKDRLEHALVVDAI 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 311 RNdiGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAW 390
Cdd:PRK07054 317 RA--ALAPLSRALDIPDQPSLHRLPRLQHLSTPIRATLAPDATLLQVVAALHPTPAVGGHPRAAALDYIRAHEGFDRGWY 394
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446777763 391 CGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQET 440
Cdd:PRK07054 395 AAPIGWLDAHGNGDFAVALRSALITGGACRLFAGCGIVADSEPASEYRET 444
|
|
| PRK06923 |
PRK06923 |
isochorismate synthase DhbC; Validated |
166-451 |
2.20e-20 |
|
isochorismate synthase DhbC; Validated
Pssm-ID: 235886 [Multi-domain] Cd Length: 399 Bit Score: 92.49 E-value: 2.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 166 WLESQQFSP----QEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP- 240
Cdd:PRK06923 93 ISERLQLDTtnhlEINRNLTFEMTPVPDPEVYMNGVKQGIAKIQDGDLKKIVLSRSLDVKSSEKIDKQKLLRELAEHNKh 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 241 ---FSAFLRLEQG----AILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDlmrnd 313
Cdd:PRK06923 173 gytFAVNLPKDENenskTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVE----- 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 314 igrvAVAGSVK-------VPELFVVEPFPAVHHLVSTITAQLPEQLHAS-DLLRAAFPGGSITGAPKVRAMEIIDELEPQ 385
Cdd:PRK06923 248 ----AVAAALRpychtlhVPEKPSVIHTEAMWHLSTEVKGELKDPNTSSlELAIALHPTPAVCGTPTEEAREAIQQIEPF 323
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446777763 386 RRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQL 451
Cdd:PRK06923 324 DREFFTGMLGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKAM 389
|
|
| PRK07912 |
PRK07912 |
salicylate synthase; |
209-447 |
7.84e-20 |
|
salicylate synthase;
Pssm-ID: 169151 [Multi-domain] Cd Length: 449 Bit Score: 91.39 E-value: 7.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 209 CYQVNLAQRFHATYsgdewqaflQLNQANRAPFSAFLrLEQGAILSL--SPERFILCDNSE-IQTRPIKGTLPRLPDPQE 285
Cdd:PRK07912 210 CVEVPFAVDFPATY---------RLGRRHNTPVRSFL-LRLGGIRALgySPELVTAVRADGvVITEPLAGTRAFGRGAAI 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 286 DSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGG 365
Cdd:PRK07912 280 DRLARDDLESNSKEIVEHAISVRSSLAEITEIAEPGSAAVIDFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAV 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 366 SITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVN 445
Cdd:PRK07912 360 TASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLS 439
|
..
gi 446777763 446 KI 447
Cdd:PRK07912 440 TL 441
|
|
| PRK06772 |
PRK06772 |
salicylate synthase; |
235-447 |
1.61e-19 |
|
salicylate synthase;
Pssm-ID: 102546 [Multi-domain] Cd Length: 434 Bit Score: 90.57 E-value: 1.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 235 QANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDI 314
Cdd:PRK06772 217 QANTPVRSFMFRQEGREALGFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAEL 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 315 GRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSI 394
Cdd:PRK06772 297 EAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAI 376
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446777763 395 GYLSFCgNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKI 447
Cdd:PRK06772 377 LLLDDT-RFDAALVLRSVFQDSQRCWIQAGAGIIAQSTPERELTETREKLASI 428
|
|
| PRK15016 |
PRK15016 |
isochorismate synthase EntC; Provisional |
237-448 |
3.69e-16 |
|
isochorismate synthase EntC; Provisional
Pssm-ID: 184977 [Multi-domain] Cd Length: 391 Bit Score: 79.92 E-value: 3.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 237 NRAPFSAFLRLEQG-AILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIG 315
Cdd:PRK15016 175 NPVSYNFHVPLADGgVLLGASPELLLRKDGERFSSLPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLR 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 316 ----RVAVAGSvkvPELFVVepfPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWC 391
Cdd:PRK15016 255 erssELHVPSS---PQLITT---PTLWHLATPFEGKANAQENALTLACLLHPTPALSGFPHQAAKQVIAELEPFDRELFG 328
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446777763 392 GSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKIL 448
Cdd:PRK15016 329 GIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTML 385
|
|
| PRK15012 |
PRK15012 |
menaquinone-specific isochorismate synthase; Provisional |
249-443 |
1.23e-09 |
|
menaquinone-specific isochorismate synthase; Provisional
Pssm-ID: 184974 [Multi-domain] Cd Length: 431 Bit Score: 59.86 E-value: 1.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 249 QGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPEl 328
Cdd:PRK15012 231 ENAFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQ- 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 329 fvVEPFPAVHHLVSTITAQLPeqlHASD--LLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLS-----FCg 401
Cdd:PRK15012 310 --VLRLRKVQHLRRCIWTSLN---KADDviCLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSlqqseFC- 383
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446777763 402 nmdtsITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDK 443
Cdd:PRK15012 384 -----VSLRSAKVSGNVVRLYAGAGIVRGSDPEQEWQEIDNK 420
|
|
| PLN02786 |
PLN02786 |
isochorismate synthase |
206-453 |
7.00e-09 |
|
isochorismate synthase
Pssm-ID: 178383 [Multi-domain] Cd Length: 533 Bit Score: 57.87 E-value: 7.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 206 SGDCYQVNLAQRFHATYSGD----EWQAFLQLNQANRAPFsaFLRLEQG-AILSLSPERFI----LCDNSEiqtrPIKGT 276
Cdd:PLN02786 277 SSPLKKVVLARSSRIITDTDidpiAWLACLQVEGQNAYQF--CLQPPDApAFIGNTPEQLFhrkgLGVCSE----ALAAT 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 277 LPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIgrVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASD 356
Cdd:PLN02786 351 RPRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKL--EAICDRVVVEPHKAIRKLARVQHLYAQLAGRLRSEDDEFD 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446777763 357 LLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLsfcGNMDT--SITIRTLTAINGQ---IYcsAGGGIVADS 431
Cdd:PLN02786 429 ILAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWF---GGGESefAVGIRSALVEKGLgalIY--AGTGIVEGS 503
|
250 260
....*....|....*....|..
gi 446777763 432 QEEAEYQETFDKVNKILRQLEK 453
Cdd:PLN02786 504 NPSSEWNELELKISQFTKSLEH 525
|
|
| |
