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Conserved domains on  [gi|446791322|ref|WP_000868578|]
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MULTISPECIES: phosphatase PAP2 family protein [Bacillus]

Protein Classification

PgpB family protein( domain architecture ID 11430553)

PgpB family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 28-172 9.94e-21

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


:

Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 84.32  E-value: 9.94e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  28 IFFSNITHIGGATFSIALTLFFLIFAKGTLHQAAIAAAISLAISHIPVQILKRWYPRKRPYLTiQDAKYPVHPLKDHSFP 107
Cdd:COG0671   42 ALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRPRPFVV-PDLELLLGTAGGYSFP 120

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446791322 108 SGHTTAVFSVFIPFICYNPSLLAFLLPLA--LCVGISRIYLGLHYPSDVFVGMCLGTCSGIISFYQF 172
Cdd:COG0671  121 SGHAAAAFALALVLALLLPRRWLAALLLAlaLLVGLSRVYLGVHYPSDVLAGALLGLAIALLLLALL 187
 
Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 28-172 9.94e-21

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 84.32  E-value: 9.94e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  28 IFFSNITHIGGATFSIALTLFFLIFAKGTLHQAAIAAAISLAISHIPVQILKRWYPRKRPYLTiQDAKYPVHPLKDHSFP 107
Cdd:COG0671   42 ALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRPRPFVV-PDLELLLGTAGGYSFP 120

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446791322 108 SGHTTAVFSVFIPFICYNPSLLAFLLPLA--LCVGISRIYLGLHYPSDVFVGMCLGTCSGIISFYQF 172
Cdd:COG0671  121 SGHAAAAFALALVLALLLPRRWLAALLLAlaLLVGLSRVYLGVHYPSDVLAGALLGLAIALLLLALL 187
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 75-169 2.11e-18

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 76.35  E-value: 2.11e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  75 VQILKRWYPRKRPYLTIQDAKYPVHPL---KDHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLA------LCVGISRIY 145
Cdd:cd01610   19 TGVLKYLFGRPRPYFLLRCGPDGDPLLlteGGYSFPSGHAAFAFALALFLALLLPRRLLRLLLGLlllllaLLVGLSRVY 98

                         90       100
                 ....*....|....*....|....
gi 446791322 146 LGLHYPSDVFVGMCLGTCSGIISF 169
Cdd:cd01610   99 LGVHYPSDVLAGALLGILVALLVL 122
acidPPc smart00014
Acid phosphatase homologues;
77-169 1.72e-12

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 60.82  E-value: 1.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322    77 ILKRWYPRKRPYLTIQD--AKYPVHPLK---DHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLAL------CVGISRIY 145
Cdd:smart00014  13 VIKNYFGRPRPFFLSIGdaCCTPNFLLTleaGYSFPSGHTAFAFAFALFLLLYLPARAGRKLLIFLllllalVVGFSRVY 92

                           90       100
                   ....*....|....*....|....
gi 446791322   146 LGLHYPSDVFVGMCLGTCSGIISF 169
Cdd:smart00014  93 LGAHWPSDVLAGSLLGILIAAVLF 116
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 75-172 2.06e-12

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 60.90  E-value: 2.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322   75 VQILKRWYPRKRPYLTIQDAKY----PVHPLKDHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLAL--------CVGIS 142
Cdd:pfam01569  13 SSVLKDYFGRPRPFFLLLEGGLvpapSTLPGLGYSFPSGHSATAFALALLLALLLRRLRKIVRVLLAllllvlalLVGLS 92

                          90       100       110
                  ....*....|....*....|....*....|
gi 446791322  143 RIYLGLHYPSDVFVGMCLGTCSGIISFYQF 172
Cdd:pfam01569  93 RLYLGVHFPSDVLAGALIGILLALLVYRLV 122
PRK11837 PRK11837
undecaprenyl pyrophosphate phosphatase; Provisional
 103-164 3.96e-05

undecaprenyl pyrophosphate phosphatase; Provisional


Pssm-ID: 183335  Cd Length: 202  Bit Score: 42.31  E-value: 3.96e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446791322 103 DHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLALC-VGISRIYLGLHYPSDVFVGMCLGTCS 164
Cdd:PRK11837 102 DDSFPSDHGTVIFTFALAFLFWHRLWSGSLLMAIAVaIAWSRVYLGVHWPLDMLGALLVGMIG 164
 
Name Accession Description Interval E-value
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 28-172 9.94e-21

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 84.32  E-value: 9.94e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  28 IFFSNITHIGGATFSIALTLFFLIFAKGTLHQAAIAAAISLAISHIPVQILKRWYPRKRPYLTiQDAKYPVHPLKDHSFP 107
Cdd:COG0671   42 ALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALLLLLLLLLLLLLKYLFGRPRPFVV-PDLELLLGTAGGYSFP 120

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446791322 108 SGHTTAVFSVFIPFICYNPSLLAFLLPLA--LCVGISRIYLGLHYPSDVFVGMCLGTCSGIISFYQF 172
Cdd:COG0671  121 SGHAAAAFALALVLALLLPRRWLAALLLAlaLLVGLSRVYLGVHYPSDVLAGALLGLAIALLLLALL 187
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 75-169 2.11e-18

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 76.35  E-value: 2.11e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  75 VQILKRWYPRKRPYLTIQDAKYPVHPL---KDHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLA------LCVGISRIY 145
Cdd:cd01610   19 TGVLKYLFGRPRPYFLLRCGPDGDPLLlteGGYSFPSGHAAFAFALALFLALLLPRRLLRLLLGLlllllaLLVGLSRVY 98

                         90       100
                 ....*....|....*....|....
gi 446791322 146 LGLHYPSDVFVGMCLGTCSGIISF 169
Cdd:cd01610   99 LGVHYPSDVLAGALLGILVALLVL 122
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 19-171 1.96e-14

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 67.63  E-value: 1.96e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  19 RYFDQKTLNIFFSNITHIGGATFSIALTLFFLIFAkgTLHQAAIAAAISLAIS---HIPVQILKRWYPRKRPYLtiqdak 95
Cdd:cd03392   21 RSLRTPLLTAFMTAITFLGSPAVLLIIVLLLALLL--LLKRRRRAALFLLLALlggGALNTLLKLLVQRPRPPL------ 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  96 ypVHPLKDH--SFPSGHTTAVFsVFIPFICY-----NPSLLAFLLPLALC------VGISRIYLGLHYPSDVFVGMCLGT 162
Cdd:cd03392   93 --HLLVPEGgySFPSGHAMGAT-VLYGFLAYllarrLPRRRVRILLLILAailillVGLSRLYLGVHYPSDVLAGWLLGL 169

                        170
                 ....*....|.
gi 446791322 163 --CSGIISFYQ 171
Cdd:cd03392  170 awLALLILLYR 180
acidPPc smart00014
Acid phosphatase homologues;
77-169 1.72e-12

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 60.82  E-value: 1.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322    77 ILKRWYPRKRPYLTIQD--AKYPVHPLK---DHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLAL------CVGISRIY 145
Cdd:smart00014  13 VIKNYFGRPRPFFLSIGdaCCTPNFLLTleaGYSFPSGHTAFAFAFALFLLLYLPARAGRKLLIFLllllalVVGFSRVY 92

                           90       100
                   ....*....|....*....|....
gi 446791322   146 LGLHYPSDVFVGMCLGTCSGIISF 169
Cdd:smart00014  93 LGAHWPSDVLAGSLLGILIAAVLF 116
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 75-172 2.06e-12

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 60.90  E-value: 2.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322   75 VQILKRWYPRKRPYLTIQDAKY----PVHPLKDHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLAL--------CVGIS 142
Cdd:pfam01569  13 SSVLKDYFGRPRPFFLLLEGGLvpapSTLPGLGYSFPSGHSATAFALALLLALLLRRLRKIVRVLLAllllvlalLVGLS 92

                          90       100       110
                  ....*....|....*....|....*....|
gi 446791322  143 RIYLGLHYPSDVFVGMCLGTCSGIISFYQF 172
Cdd:pfam01569  93 RLYLGVHFPSDVLAGALIGILLALLVYRLV 122
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 13-165 3.56e-12

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 61.51  E-value: 3.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  13 IFKGINRYFDQKTLNIFFSNITHIGGATFSIALTLFFLIFAKG--TLHQAAIAAAISLAISHIPVQILKRWYPRKRPYLT 90
Cdd:cd03395    9 LFLLLNGTLVHPLLDDLMPFLTGKKLSVPIFLLLALFILFRKGpiGLLILLLVLLAVGFADQLASGFLKPLVARLRPCNA 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446791322  91 IQDAKYPVHPLKDH--SFPSGHTTAVFSVFIPFICYNPSLLAFLLPLALC--VGISRIYLGLHYPSDVFVGMCLGTCSG 165
Cdd:cd03395   89 LDGVRLVVLGDQGGsySFASSHAANSFALALFIWLFFRRGLFSPVLLLWAllVGYSRVYVGVHYPGDVIAGALIGIISG 167
PAP2_lipid_A_1_phosphatase cd03389
PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from ...
 19-162 8.86e-12

PAP2_like proteins, Lipid A 1-phosphatase subfamily. Lipid A 1-phosphatase, or LpxE from Francisella novicida selectively dephosphorylates lipid A at the 1-position. Lipid A is the membrane-anchor component of lipopolysaccharides (LPS), the major constituents of the outer membrane in many gram-negative bacteria.


Pssm-ID: 239483  Cd Length: 186  Bit Score: 60.41  E-value: 8.86e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  19 RYFDQKTLNIFFSNITHIGGATF----SIALTLFFLIFAKGTLHQAAIAAAISLAIS-----------HIPVQILKRWYP 83
Cdd:cd03389   14 KALDGRILAGFFRTITDFGKSGWylipSLLLFLLFRFGDLRGLSAPSRARFPKAAWAglflfatvalsGILVNLLKFIIG 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  84 RKRPYLTIQDAKYPVHPLKDH----SFPSGHTTAVFSVFIPFICYNPSLLAFLLPLALCVGISRIYLGLHYPSDVFVGMC 159
Cdd:cd03389   94 RARPKLLFDDGLYGFDPFHADyaftSFPSGHSATAGAAAAALALLFPRYRWAFILLALLIAFSRVIVGAHYPSDVIAGSL 173


                 ...
gi 446791322 160 LGT 162
Cdd:cd03389  174 LGA 176
PAP2_BcrC_like cd03385
PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as ...
 82-170 3.19e-10

PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from Bacillus subtilis posesses undecaprenyl pyrophosphate (UPP) phospatase activity, and it is hypothesized that it competes with bacitracin for UPP, increasing the cell's resistance to bacitracin.


Pssm-ID: 239480  Cd Length: 144  Bit Score: 55.34  E-value: 3.19e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  82 YPRKRPYltiqdAKYPVHPLKDH----SFPSGHTTAVFSVFIPFICYN-PSLLAFLLPLALCVGISRIYLGLHYPSDVFV 156
Cdd:cd03385   56 YFHPRPF-----VVGLGHNLLPHaadsSFPSDHTTLFFSIAFSLLLRRrKWAGWILLILALLVAWSRIYLGVHYPLDMLG 130

                         90
                 ....*....|....
gi 446791322 157 GMCLGTCSGIISFY 170
Cdd:cd03385  131 AALVAVLSALLVFQ 144
PAP2_like_1 cd03380
PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium ...
 79-162 2.14e-09

PAP2_like_1 proteins, a sub-family of PAP2, containing bacterial acid phosphatase, vanadium chloroperoxidases and vanadium bromoperoxidases.


Pssm-ID: 239475  Cd Length: 209  Bit Score: 54.36  E-value: 2.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  79 KRWYPRKRPYLTIQD---------AKYPVHPlkdhSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLALCVGISRIYLGLH 149
Cdd:cd03380  113 KYHYNRPRPFVAIRLqwlpictpeEGTPKHP----SYPSGHATFGGAAALVLAELFPERAAELLARAAEAGNSRVVAGVH 188

                         90
                 ....*....|...
gi 446791322 150 YPSDVFVGMCLGT 162
Cdd:cd03380  189 WPSDVEAGRILGE 201
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 75-165 4.38e-09

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 51.56  E-value: 4.38e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  75 VQILKRWYPRKRPYLTIQDakypvhplkDHSFPSGHTTAVFSV--FIPFICYNPSLLAFLLPLALCVGISRIYLGLHYPS 152
Cdd:cd03394   19 TEGLKFAVGRARPDGSNNG---------YRSFPSGHTASAFAAatFLQYRYGWRWYGIPAYALASLVGASRVVANRHWLS 89

                         90
                 ....*....|...
gi 446791322 153 DVFVGMCLGTCSG 165
Cdd:cd03394   90 DVLAGAAIGILVG 102
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 75-161 1.44e-07

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 48.47  E-value: 1.44e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  75 VQILKRWYPRKRPYLTIQDAKYPVHPlkDH-SFPSGHTTAVFSVFIPFICYNPSLLAFLLPLA---LCVGISRIYLGLHY 150
Cdd:cd03391   63 VAILKALVRRRRPAYNSPDMLDYVAV--DKySFPSGHASRAAFVARFLLNHLVLAVPLRVLLVlwaTVVGISRVLLGRHH 140

                         90
                 ....*....|.
gi 446791322 151 PSDVFVGMCLG 161
Cdd:cd03391  141 VLDVLAGAFLG 151
PAP2_haloperoxidase cd03398
PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as ...
 97-161 1.89e-06

PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles.


Pssm-ID: 239492  Cd Length: 232  Bit Score: 46.26  E-value: 1.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  97 PVHPlkdhSFPSGHTT---AVFSV---FIP--FICYNPSLLAFLLPLALC-------------VGISRIYLGLHYPSDVF 155
Cdd:cd03398  142 PPHP----SYPSGHATfagAAATVlkaLFGsdKVPDTVSEPDEGGPSTGVtrvwaelneladeVAISRVYAGVHFRSDDA 217


                 ....*.
gi 446791322 156 VGMCLG 161
Cdd:cd03398  218 AGAALG 223
PAP2_acid_phosphatase cd03397
PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes ...
 79-154 1.89e-05

PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains to be determined.


Pssm-ID: 239491  Cd Length: 232  Bit Score: 43.48  E-value: 1.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322  79 KRWYPRKRPYLTIQDAKYPV----HPLKDHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLALCVGISRIYLGLHYPSDV 154
Cdd:cd03397  121 KKYYNRPRPFVLNDEPICTPpdesGLAKDGSYPSGHTAAGYAWALILAELVPERADEILARGSEYGQSRIVCGVHWPSDV 200
PRK11837 PRK11837
undecaprenyl pyrophosphate phosphatase; Provisional
 103-164 3.96e-05

undecaprenyl pyrophosphate phosphatase; Provisional


Pssm-ID: 183335  Cd Length: 202  Bit Score: 42.31  E-value: 3.96e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446791322 103 DHSFPSGHTTAVFSVFIPFICYNPSLLAFLLPLALC-VGISRIYLGLHYPSDVFVGMCLGTCS 164
Cdd:PRK11837 102 DDSFPSDHGTVIFTFALAFLFWHRLWSGSLLMAIAVaIAWSRVYLGVHWPLDMLGALLVGMIG 164
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 104-172 5.88e-05

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 41.82  E-value: 5.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446791322 104 HSFPSGHTTAVFSVFIPFI--------CYNPSLLAFLLPLA-------LCVGISRIYLGLHYPSDVFVGMCLGTCSGIIS 168
Cdd:cd03390  110 KSFPSGHSSFAFAGLGFLSlylagklhIFDPRGSSWRLLLAllplllaILVAVSRTRDYRHHFSDVIAGSLIGLIIAYLS 189


                 ....
gi 446791322 169 FYQF 172
Cdd:cd03390  190 YRQY 193
PAP2_SPPase1 cd03388
PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an ...
 97-161 1.34e-04

PAP2_like proteins, sphingosine-1-phosphatase subfamily. Sphingosine-1-phosphatase is an intracellular enzyme located in the endoplasmic reticulum, which regulates the level of sphingosine-1-phosphate (S1P), a bioactive lipid. S1P acts as a second messenger in the cell, and extracellularly by binding to G-protein coupled receptors of the endothelial differentiation gene family.


Pssm-ID: 239482  Cd Length: 151  Bit Score: 40.29  E-value: 1.34e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446791322  97 PVHPL------KDHSFPSGHTTAVFSVFIPFICY--------NPSLLAFLLPLALCVGISRIYLGLHYPSDVFVGMCLG 161
Cdd:cd03388   65 PVVRLtmssaaLEYGFPSTHAMNATAISFYLLIYlydryqypFVLGLILALFYSTLVCLSRIYMGMHSVLDVIAGSLIG 143
PAP2_like_3 cd03393
PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 105-161 4.53e-04

PAP2_like_3 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria and archaea, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239487 [Multi-domain]  Cd Length: 125  Bit Score: 38.51  E-value: 4.53e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446791322 105 SFPSGH--TTAVFSVFIPFICYNPSLLAFLLPLALCVGISRIYLGLHYPSDVFVGMCLG 161
Cdd:cd03393   59 GFPSGHaqTSATFWGSLMLHVRKKWFTLIGVVLVVLISFSRLYLGVHWPSDVIGGVLIG 117
PLN02525 PLN02525
phosphatidic acid phosphatase family protein
 139-163 6.51e-03

phosphatidic acid phosphatase family protein


Pssm-ID: 215288  Cd Length: 352  Bit Score: 36.25  E-value: 6.51e-03
                         10        20
                 ....*....|....*....|....*
gi 446791322 139 VGISRIYLGLHYPSDVFVGMCLGTC 163
Cdd:PLN02525 131 VGFGRLYLGMHSPIDIIAGLAIGLV 155
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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