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Conserved domains on  [gi|446847878|ref|WP_000925134|]
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MULTISPECIES: DUF4937 domain-containing protein [Bacillus]

Protein Classification

DUF4937 and ABM domain-containing protein( domain architecture ID 11242187)

DUF4937 and ABM domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4937 pfam16291
Domain of unknown function (DUF4937; This family consists of uncharacterized proteins around ...
 2-87 4.87e-44

Domain of unknown function (DUF4937; This family consists of uncharacterized proteins around 120 residues in length and is mainly found in various Bacillus species, such as Bacillus subtilis and Bacillus amyloliquefaciens. Several members are annotated as ydbC, but the specific function of this family is unknown.


:

Pssm-ID: 406653  Cd Length: 89  Bit Score: 142.15  E-value: 4.87e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446847878    2 LLKTIFCKVGEEKREMFSAAQEKWRDLQHLDGFHGQFGGWN---EDEACVYTLWEDRSAYQSFMNGAHDTIYLNSNQKDT 78
Cdd:pfam16291   1 LVKYIRCEVDDQKREAFSKAQAKWAALAHVPGFIGQAGGWSredPGTAIIFALWEDRAAYDEFMANEHDSIYEATKQAGT 80


                  ....*....
gi 446847878   79 FLSCEIELF 87
Cdd:pfam16291  81 YSSISVSLF 89
HmoA COG2329
Heme-degrading monooxygenase HmoA and related ABM domain proteins [Coenzyme transport and ...
 135-169 7.71e-05

Heme-degrading monooxygenase HmoA and related ABM domain proteins [Coenzyme transport and metabolism];


:

Pssm-ID: 441901  Cd Length: 98  Bit Score: 40.36  E-value: 7.71e-05
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 446847878 135 MENAKGMLGGVVAKSLKNETRYIVLTYWEDEMAHQ 169
Cdd:COG2329   29 LAEQPGFLGFELLRSLEDPGEYLVVSYWESEEAFR 63
 
Name Accession Description Interval E-value
DUF4937 pfam16291
Domain of unknown function (DUF4937; This family consists of uncharacterized proteins around ...
 2-87 4.87e-44

Domain of unknown function (DUF4937; This family consists of uncharacterized proteins around 120 residues in length and is mainly found in various Bacillus species, such as Bacillus subtilis and Bacillus amyloliquefaciens. Several members are annotated as ydbC, but the specific function of this family is unknown.


Pssm-ID: 406653  Cd Length: 89  Bit Score: 142.15  E-value: 4.87e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446847878    2 LLKTIFCKVGEEKREMFSAAQEKWRDLQHLDGFHGQFGGWN---EDEACVYTLWEDRSAYQSFMNGAHDTIYLNSNQKDT 78
Cdd:pfam16291   1 LVKYIRCEVDDQKREAFSKAQAKWAALAHVPGFIGQAGGWSredPGTAIIFALWEDRAAYDEFMANEHDSIYEATKQAGT 80


                  ....*....
gi 446847878   79 FLSCEIELF 87
Cdd:pfam16291  81 YSSISVSLF 89
HmoA COG2329
Heme-degrading monooxygenase HmoA and related ABM domain proteins [Coenzyme transport and ...
 135-169 7.71e-05

Heme-degrading monooxygenase HmoA and related ABM domain proteins [Coenzyme transport and metabolism];


Pssm-ID: 441901  Cd Length: 98  Bit Score: 40.36  E-value: 7.71e-05
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 446847878 135 MENAKGMLGGVVAKSLKNETRYIVLTYWEDEMAHQ 169
Cdd:COG2329   29 LAEQPGFLGFELLRSLEDPGEYLVVSYWESEEAFR 63
ABM pfam03992
Antibiotic biosynthesis monooxygenase; This domain is found in monooxygenases involved in the ...
 107-169 8.86e-03

Antibiotic biosynthesis monooxygenase; This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.


Pssm-ID: 427635  Cd Length: 74  Bit Score: 33.78  E-value: 8.86e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446847878  107 FVRVAICDVKGEKENHFLHKQETIwNKGMENAKGMLGGVVAKSLKNETRYIVLTYWEDEMAHQ 169
Cdd:pfam03992   1 IVVVAEIRVKPGKAEEFEEALAEL-VEATRNEPGCLSYELLRSLEDPDEYVVLEVWEDEAAFE 62
 
Name Accession Description Interval E-value
DUF4937 pfam16291
Domain of unknown function (DUF4937; This family consists of uncharacterized proteins around ...
 2-87 4.87e-44

Domain of unknown function (DUF4937; This family consists of uncharacterized proteins around 120 residues in length and is mainly found in various Bacillus species, such as Bacillus subtilis and Bacillus amyloliquefaciens. Several members are annotated as ydbC, but the specific function of this family is unknown.


Pssm-ID: 406653  Cd Length: 89  Bit Score: 142.15  E-value: 4.87e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446847878    2 LLKTIFCKVGEEKREMFSAAQEKWRDLQHLDGFHGQFGGWN---EDEACVYTLWEDRSAYQSFMNGAHDTIYLNSNQKDT 78
Cdd:pfam16291   1 LVKYIRCEVDDQKREAFSKAQAKWAALAHVPGFIGQAGGWSredPGTAIIFALWEDRAAYDEFMANEHDSIYEATKQAGT 80


                  ....*....
gi 446847878   79 FLSCEIELF 87
Cdd:pfam16291  81 YSSISVSLF 89
HmoA COG2329
Heme-degrading monooxygenase HmoA and related ABM domain proteins [Coenzyme transport and ...
 135-169 7.71e-05

Heme-degrading monooxygenase HmoA and related ABM domain proteins [Coenzyme transport and metabolism];


Pssm-ID: 441901  Cd Length: 98  Bit Score: 40.36  E-value: 7.71e-05
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 446847878 135 MENAKGMLGGVVAKSLKNETRYIVLTYWEDEMAHQ 169
Cdd:COG2329   29 LAEQPGFLGFELLRSLEDPGEYLVVSYWESEEAFR 63
ABM pfam03992
Antibiotic biosynthesis monooxygenase; This domain is found in monooxygenases involved in the ...
 107-169 8.86e-03

Antibiotic biosynthesis monooxygenase; This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.


Pssm-ID: 427635  Cd Length: 74  Bit Score: 33.78  E-value: 8.86e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446847878  107 FVRVAICDVKGEKENHFLHKQETIwNKGMENAKGMLGGVVAKSLKNETRYIVLTYWEDEMAHQ 169
Cdd:pfam03992   1 IVVVAEIRVKPGKAEEFEEALAEL-VEATRNEPGCLSYELLRSLEDPDEYVVLEVWEDEAAFE 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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