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Conserved domains on  [gi|446862537|ref|WP_000939793|]
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MULTISPECIES: enoyl-CoA hydratase [Bacillus]

Protein Classification

Clp protease/crotonase-like domain-containing protein; enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10792970)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate| enoyl-CoA hydratase/isomerase family protein similar to enoyl-CoA hydratase, which catalyzes the second step in the beta-oxidation pathway of fatty acid metabolism, the syn-addition of a water molecule across the double bond of a trans-2-enoyl-CoA thioester, resulting in the formation of a beta-hydroxyacyl-CoA thioester

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
3-262 6.79e-175

enoyl-CoA hydratase; Provisional


:

Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 481.93  E-value: 6.79e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   3 QLQNISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVR 82
Cdd:PRK07657   1 MLQNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  83 HAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 162
Cdd:PRK07657  81 HAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 163 LIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTK 242
Cdd:PRK07657 161 LIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTK 240
                        250       260
                 ....*....|....*....|
gi 446862537 243 DRIEGLQAFKEKRKPMYKGE 262
Cdd:PRK07657 241 DRLEGLQAFKEKRKPMYKGE 260
 
Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
3-262 6.79e-175

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 481.93  E-value: 6.79e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   3 QLQNISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVR 82
Cdd:PRK07657   1 MLQNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  83 HAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 162
Cdd:PRK07657  81 HAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 163 LIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTK 242
Cdd:PRK07657 161 LIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTK 240
                        250       260
                 ....*....|....*....|
gi 446862537 243 DRIEGLQAFKEKRKPMYKGE 262
Cdd:PRK07657 241 DRLEGLQAFKEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
12-256 2.64e-97

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 285.14  E-value: 2.64e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE-RAGMNEEQVRHAVSMIRT 90
Cdd:COG1024    5 REGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKElAAAADPEEARAFARGLQR 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  91 TMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRI 170
Cdd:COG1024   84 LFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 171 SAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQA 250
Cdd:COG1024  164 DAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAA 243

                 ....*.
gi 446862537 251 FKEKRK 256
Cdd:COG1024  244 FLEKRK 249
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
12-201 2.73e-74

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 224.75  E-value: 2.73e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGM--NEEQVRHAVSMIR 89
Cdd:cd06558    5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALsdAGEEARAFIRELQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  90 TTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRR 169
Cdd:cd06558   84 ELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRR 163
                        170       180       190
                 ....*....|....*....|....*....|..
gi 446862537 170 ISAQEAKEYGLVEFVVPANLLEEKAIEIAEKI 201
Cdd:cd06558  164 ISAEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
16-261 3.32e-74

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 226.47  E-value: 3.32e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGaGEKAFCAGADLKERAGmneEQVRHAVSMIRTTMEM- 94
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYG---EGPAHQALYRENVLDLw 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   95 --VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 172
Cdd:pfam00378  82 tlLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  173 QEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFK 252
Cdd:pfam00378 162 QEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFL 241

                  ....*....
gi 446862537  253 EKRKPMYKG 261
Cdd:pfam00378 242 EKRKPPWED 250
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
16-235 1.57e-34

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 131.11  E-value: 1.57e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   16 VVKISLNRARqANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLkeraGMNE-EQVRHAVSMI----RT 90
Cdd:TIGR02441  25 VVKIDSPNSK-VNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADI----QMIAaCKTAQEVTQLsqegQE 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   91 TMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESAS--LGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGR 168
Cdd:TIGR02441 100 MFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGK 179
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446862537  169 RISAQEAKEYGLVEFVV--------PAnllEEKAIEIAEKiasngpIAVRLAKEAISNGIQVDLHTGLQMEKQAY 235
Cdd:TIGR02441 180 KIRADRAKKMGIVDQLVdplgpglkPA---EENTIEYLEE------VAVKFAQGLANGKLSINRDKGLVHKITQY 245
 
Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
3-262 6.79e-175

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 481.93  E-value: 6.79e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   3 QLQNISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVR 82
Cdd:PRK07657   1 MLQNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  83 HAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 162
Cdd:PRK07657  81 HAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 163 LIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTK 242
Cdd:PRK07657 161 LIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTK 240
                        250       260
                 ....*....|....*....|
gi 446862537 243 DRIEGLQAFKEKRKPMYKGE 262
Cdd:PRK07657 241 DRLEGLQAFKEKRKPMYKGE 260
PLN02600 PLN02600
enoyl-CoA hydratase
16-262 2.86e-98

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 287.86  E-value: 2.86e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMV 95
Cdd:PLN02600   5 IVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  96 EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 175
Cdd:PLN02600  85 EALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 176 KEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFKEKR 255
Cdd:PLN02600 165 ASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKR 244

                 ....*..
gi 446862537 256 KPMYKGE 262
Cdd:PLN02600 245 KPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
12-256 2.64e-97

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 285.14  E-value: 2.64e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE-RAGMNEEQVRHAVSMIRT 90
Cdd:COG1024    5 REGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKElAAAADPEEARAFARGLQR 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  91 TMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRI 170
Cdd:COG1024   84 LFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 171 SAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQA 250
Cdd:COG1024  164 DAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAA 243

                 ....*.
gi 446862537 251 FKEKRK 256
Cdd:COG1024  244 FLEKRK 249
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
15-261 1.04e-82

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 248.51  E-value: 1.04e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEM 94
Cdd:PRK05809  13 HIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNKVFRK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 174
Cdd:PRK05809  93 LENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINAEE 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 175 AKEYGLVEFVV-PANLLEEkAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFKE 253
Cdd:PRK05809 173 ALRIGLVNKVVePEKLMEE-AKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGMTAFVE 251

                 ....*...
gi 446862537 254 KRKPMYKG 261
Cdd:PRK05809 252 KREKNFKN 259
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
12-262 7.77e-79

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 238.38  E-value: 7.77e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRArQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNE-EQVRHAVSMIRT 90
Cdd:PRK07658   8 VEDHVAVITLNHP-PANALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFTSVTEaEQATELAQLGQV 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  91 TMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRI 170
Cdd:PRK07658  86 TFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPI 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 171 SAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQA 250
Cdd:PRK07658 166 TGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGVQA 245
                        250
                 ....*....|..
gi 446862537 251 FKEKRKPMYKGE 262
Cdd:PRK07658 246 FLEKRKPSFSGK 257
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
12-201 2.73e-74

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 224.75  E-value: 2.73e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGM--NEEQVRHAVSMIR 89
Cdd:cd06558    5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALsdAGEEARAFIRELQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  90 TTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRR 169
Cdd:cd06558   84 ELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRR 163
                        170       180       190
                 ....*....|....*....|....*....|..
gi 446862537 170 ISAQEAKEYGLVEFVVPANLLEEKAIEIAEKI 201
Cdd:cd06558  164 ISAEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
16-261 3.32e-74

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 226.47  E-value: 3.32e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGaGEKAFCAGADLKERAGmneEQVRHAVSMIRTTMEM- 94
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYG---EGPAHQALYRENVLDLw 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   95 --VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 172
Cdd:pfam00378  82 tlLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISA 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  173 QEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFK 252
Cdd:pfam00378 162 QEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFL 241

                  ....*....
gi 446862537  253 EKRKPMYKG 261
Cdd:pfam00378 242 EKRKPPWED 250
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
16-261 6.33e-73

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 223.59  E-value: 6.33e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE---RAGMNEEQVRHAVSMIRttm 92
Cdd:PRK06688  15 VLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAG-RAFSAGGDIKDfpkAPPKPPDELAPVNRFLR--- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  93 eMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 172
Cdd:PRK06688  91 -AIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 173 QEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFK 252
Cdd:PRK06688 170 EEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATAFI 249

                 ....*....
gi 446862537 253 EKRKPMYKG 261
Cdd:PRK06688 250 EKRKPDFTG 258
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
15-261 1.71e-68

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 212.21  E-value: 1.71e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQV----------RHA 84
Cdd:PRK06494  13 HVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKRGWpesgfggltsRFD 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  85 vsmirttmemveqLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 164
Cdd:PRK06494  93 -------------LDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMI 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 165 YTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGL--QMEKQAYEGVIHTK 242
Cdd:PRK06494 160 LTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAItaQRDYPAVEARRASQ 239
                        250
                 ....*....|....*....
gi 446862537 243 DRIEGLQAFKEKRKPMYKG 261
Cdd:PRK06494 240 DYIEGPKAFAEKRPPRWKG 258
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
16-261 3.23e-68

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 211.55  E-value: 3.23e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAgEKAFCAGADLKEragMNEEQVRHAVSMIRTTM-EM 94
Cdd:PRK09674  12 VLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGN-ARFFAAGADLNE---MAEKDLAATLNDPRPQLwQR 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 174
Cdd:PRK09674  88 LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQ 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 175 AKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFKEK 254
Cdd:PRK09674 168 AQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISAFLEK 247

                 ....*..
gi 446862537 255 RKPMYKG 261
Cdd:PRK09674 248 RTPDFKG 254
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
19-260 6.18e-66

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 205.66  E-value: 6.18e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  19 ISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAgEKAFCAGADLKERAGMNEEQVRHAvSMIrTTMEMVEQL 98
Cdd:PRK05862  17 ITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIKEMADLSFMDVYKG-DYI-TNWEKVARI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  99 PQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEY 178
Cdd:PRK05862  94 RKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERA 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 179 GLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFKEKRKPM 258
Cdd:PRK05862 174 GLVSRVVPADKLLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVEKRKPV 253

                 ..
gi 446862537 259 YK 260
Cdd:PRK05862 254 FK 255
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
7-262 4.08e-63

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 198.74  E-value: 4.08e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   7 ISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGaGEKAFCAGADLKE--RAGMNEEQVRHA 84
Cdd:PRK08138   9 VLLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEfaTAGAIEMYLRHT 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  85 vsmiRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 164
Cdd:PRK08138  88 ----ERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMA 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 165 YTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDR 244
Cdd:PRK08138 164 LTGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQ 243
                        250
                 ....*....|....*...
gi 446862537 245 IEGLQAFKEKRKPMYKGE 262
Cdd:PRK08138 244 KEGMDAFLEKRKPAYKGK 261
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
15-260 5.46e-62

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 195.52  E-value: 5.46e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRArQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEqvrHAVSMIRTTMEM 94
Cdd:PRK09076  12 HVAILTLNNP-PANTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKA---VAREMARRFGEA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 VEQLPQ---PVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 171
Cdd:PRK09076  88 FEALSAfrgVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVD 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 172 AQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAF 251
Cdd:PRK09076 168 AATALRIGLVEEVVEKGEAREAALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAF 247

                 ....*....
gi 446862537 252 KEKRKPMYK 260
Cdd:PRK09076 248 LEKRAPQWK 256
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
15-262 3.22e-61

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 194.03  E-value: 3.22e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLS-LALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLK---ERAGMNE-------EQVRH 83
Cdd:PRK09245  12 HIVTLTMNRPETRNALSdNDAVDALVAACAAINADRSVRAVILTGAG-TAFSSGGNVKdmrARVGAFGgspadirQGYRH 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  84 AVSMIRTTMEmveQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL 163
Cdd:PRK09245  91 GIQRIPLALY---NLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEM 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 164 IYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKqAYEGVIH-TK 242
Cdd:PRK09245 168 AFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSA-AYQALAHhTA 246
                        250       260
                 ....*....|....*....|
gi 446862537 243 DRIEGLQAFKEKRKPMYKGE 262
Cdd:PRK09245 247 DHREAVDAFLEKRPPVFTGR 266
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
16-259 5.50e-61

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 193.05  E-value: 5.50e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVRHAV-SMIRTTMEM 94
Cdd:PRK05980  13 IALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVALrDFVRRGQAM 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 ---VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 171
Cdd:PRK05980  93 tarLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELLLTGDAFS 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 172 AQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAF 251
Cdd:PRK05980 173 AERALEIGLVNAVVPHEELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLREGLAAW 252

                 ....*...
gi 446862537 252 KEKRKPMY 259
Cdd:PRK05980 253 IERRRPAY 260
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
15-262 2.37e-60

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 191.45  E-value: 2.37e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARqANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEM 94
Cdd:PRK03580  12 SILEITLDRPK-ANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEI 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 VEqLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 174
Cdd:PRK03580  91 FD-LDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEE 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 175 AKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQ-MEKQA---YEGVIHTKDRIEGLQA 250
Cdd:PRK03580 170 ALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRyIRSGVlkhYPSVLHSEDALEGPRA 249
                        250
                 ....*....|..
gi 446862537 251 FKEKRKPMYKGE 262
Cdd:PRK03580 250 FAEKRDPVWKGR 261
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
15-262 5.15e-55

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 177.99  E-value: 5.15e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNE-EQVR---HAVSMIRT 90
Cdd:PRK07799  14 HTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAG-GAFCAGMDLKAATKKPPgDSFKdgsYDPSRIDA 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  91 TMEMvEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRI 170
Cdd:PRK07799  93 LLKG-RRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHI 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 171 SAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQA 250
Cdd:PRK07799 172 TAAEAKEIGLIGHVVPDGQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEGPRA 251
                        250
                 ....*....|..
gi 446862537 251 FKEKRKPMYKGE 262
Cdd:PRK07799 252 FAEKRAPNFQGR 263
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
13-234 1.04e-53

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 174.39  E-value: 1.04e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  13 TPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGmnEEQVRHAVSMIRTTM 92
Cdd:PRK06190  11 HDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGAD-PAFCAGLDLKELGG--DGSAYGAQDALPNPS 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  93 EMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 172
Cdd:PRK06190  88 PAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDA 167
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446862537 173 QEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQA 234
Cdd:PRK06190 168 ADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAEA 229
PLN02888 PLN02888
enoyl-CoA hydratase
7-255 1.16e-52

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 171.86  E-value: 1.16e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   7 ISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKeragmNEEQVRHAVS 86
Cdd:PLN02888  11 ILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSG-RAFCSGVDLT-----AAEEVFKGDV 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  87 MIRTTMEMV--EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 164
Cdd:PLN02888  85 KDVETDPVAqmERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVS 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 165 YTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQA----YEGVih 240
Cdd:PLN02888 165 LTAMPLTAETAERWGLVNHVVEESELLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEKERahdyYNGM-- 242
                        250
                 ....*....|....*
gi 446862537 241 TKDRIEGLQAFKEKR 255
Cdd:PLN02888 243 TKEQFQKMQEFIAGR 257
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
19-261 9.67e-52

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 169.50  E-value: 9.67e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  19 ISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGM--NEEQVRHAVSMIRTTMEMVE 96
Cdd:PRK06127  24 ITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESrsDAEAVAAYEQAVEAAQAALA 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  97 QLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAK 176
Cdd:PRK06127 104 DYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDAAEAL 183
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 177 EYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFKEKRK 256
Cdd:PRK06127 184 RIGLVHRVTAADDLETALADYAATIAGNAPLTLRAAKRAIAELLKDEPERDMAACQALVAACFDSEDYREGRAAFMEKRK 263

                 ....*
gi 446862537 257 PMYKG 261
Cdd:PRK06127 264 PVFKG 268
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
15-260 1.14e-50

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 166.59  E-value: 1.14e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNEEQVRH----------- 83
Cdd:PRK07509  12 GIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEG-GAFCAGLDVKSVASSPGNAVKLlfkrlpgnanl 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  84 --AVSMI-RttmemveQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRA 160
Cdd:PRK07509  91 aqRVSLGwR-------RLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVA 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 161 KELIYTGRRISAQEAKEYGLVEFVVPANLleEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIH 240
Cdd:PRK07509 164 RELTYTARVFSAEEALELGLVTHVSDDPL--AAALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQIRLLL 241
                        250       260
                 ....*....|....*....|
gi 446862537 241 TKDRIEGLQAFKEKRKPMYK 260
Cdd:PRK07509 242 GKNQKIAVKAQMKKRAPKFL 261
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
16-262 1.22e-49

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 163.96  E-value: 1.22e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE-RAGMNEEQVRHAVSMIRTTMEM 94
Cdd:PRK08139  21 VATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAG-KAFCAGHDLKEmRAARGLAYFRALFARCSRVMQA 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESAS-------LGLTETTlaiiPGAGGTQRLPRligvGRAKELIYTG 167
Cdd:PRK08139 100 IVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARfavpgvnIGLFCST----PMVALSRNVPR----KQAMEMLLTG 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 168 RRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEG 247
Cdd:PRK08139 172 EFIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMMAEDAEEG 251
                        250
                 ....*....|....*
gi 446862537 248 LQAFKEKRKPMYKGE 262
Cdd:PRK08139 252 IDAFLEKRPPEWRGR 266
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
12-261 3.13e-49

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 162.94  E-value: 3.13e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRArQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNEEQ-VRHAVSmiRT 90
Cdd:PRK06495  10 VSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKGRPDVIKGPgDLRAHN--RR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  91 TMEM---VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIipgAGGTQRLPRLIGVGRAKELIYTG 167
Cdd:PRK06495  86 TRECfhaIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGHSLTRRMMLTG 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 168 RRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEG 247
Cdd:PRK06495 163 YRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKTEDAKEA 242
                        250
                 ....*....|....
gi 446862537 248 LQAFKEKRKPMYKG 261
Cdd:PRK06495 243 QRAFLEKRPPVFKG 256
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
19-262 3.23e-49

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 162.85  E-value: 3.23e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  19 ISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLK-----ER--------AGMNEEQVRhav 85
Cdd:PRK08252  16 ITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAG-GTFCAGMDLKafargERpsipgrgfGGLTERPPR--- 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  86 smirttmemveqlpQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIY 165
Cdd:PRK08252  92 --------------KPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELAL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 166 TGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISngIQVDLHTGLQMEKQA--YEGVIHTKD 243
Cdd:PRK08252 158 TGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKRIVV--ESGDWSEDEMFARQRelIAPVFTSAD 235
                        250
                 ....*....|....*....
gi 446862537 244 RIEGLQAFKEKRKPMYKGE 262
Cdd:PRK08252 236 AKEGATAFAEKRAPVWTGK 254
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
1-261 4.58e-49

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 162.84  E-value: 4.58e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   1 MLQLQNISVDyVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAG----- 75
Cdd:PRK06142   2 MTTYESFTVE-LADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSG-KHFSYGIDLPAMAGvfgql 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  76 MNEEQVRHAVSMIRTTMEM------VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQ 149
Cdd:PRK06142  80 GKDGLARPRTDLRREILRLqaainaVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQ 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 150 RLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVP-ANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGL 228
Cdd:PRK06142 160 RLPRIIGDGHLRELALTGRDIDAAEAEKIGLVNRVYDdADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGL 239
                        250       260       270
                 ....*....|....*....|....*....|...
gi 446862537 229 QMEKQAYEGVIHTKDRIEGLQAFKEKRKPMYKG 261
Cdd:PRK06142 240 RYVATWNAAMLPSKDLTEAIAAHMEKRPPEFTG 272
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
15-262 1.55e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 161.23  E-value: 1.55e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQIsEDSNARVVILTGAGeKAFCAGADLKERA----------GMNEEqvRHA 84
Cdd:PRK08140  13 GVATLTLNRPDKLNSFTREMHRELREALDQV-EDDGARALLLTGAG-RGFCAGQDLADRDvtpggampdlGESIE--TFY 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  85 VSMIRttmeMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 164
Cdd:PRK08140  89 NPLVR----RLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 165 YTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDR 244
Cdd:PRK08140 165 LLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADY 244
                        250
                 ....*....|....*...
gi 446862537 245 IEGLQAFKEKRKPMYKGE 262
Cdd:PRK08140 245 AEGVSAFLEKRAPRFTGR 262
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
16-261 5.70e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 159.77  E-value: 5.70e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLK--ERAGMNEEQVRHAVSMIRTtME 93
Cdd:PRK06144  18 IARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAqfRAFSTAEDAVAYERRIDRV-LG 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  94 MVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGL-TETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 172
Cdd:PRK06144  97 ALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFpIARTLGNCLSMSNLARLVALLGAARVKDMLFTARLLEA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 173 QEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYegviHTKDRIEGLQAFK 252
Cdd:PRK06144 177 EEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDGDDLIRMCY----MSEDFREGVEAFL 252

                 ....*....
gi 446862537 253 EKRKPMYKG 261
Cdd:PRK06144 253 EKRPPKWKG 261
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
12-261 9.54e-48

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 160.17  E-value: 9.54e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADL--------------------K 71
Cdd:PRK08260  10 VADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAG-RAFCAGADLsaggntfdldaprtpveadeE 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  72 ERAGMNEEQVRHAVSmiRTTMEMVEqLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRL 151
Cdd:PRK08260  89 DRADPSDDGVRDGGG--RVTLRIFD-SLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFL 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 152 PRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASN-GPIAVRLAKEAISNGIQVD----LHt 226
Cdd:PRK08260 166 PRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNtSPVSVALTRQMMWRMAGADhpmeAH- 244
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 446862537 227 glQMEKQAYEGVIHTKDRIEGLQAFKEKRKPMYKG 261
Cdd:PRK08260 245 --RVDSRAIYSRGRSGDGKEGVSSFLEKRPAVFPG 277
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
8-222 1.09e-46

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 156.35  E-value: 1.09e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   8 SVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSM 87
Cdd:PRK06143   9 GVTRDDRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  88 IRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAiIPGAGGTQRLPRLIGVGRAKELIYTG 167
Cdd:PRK06143  89 LRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTG 167
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446862537 168 RRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAK------------EAISNGIQV 222
Cdd:PRK06143 168 ETIDAAQALAWGLVDRVVPLAELDAAVERLAASLAGCGPQALRQQKrllrewedmpldVAIDDSVAE 234
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
12-262 2.80e-46

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 155.47  E-value: 2.80e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADL---KERAGMNEEQVRHAVSMI 88
Cdd:PRK05995  10 QRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLnwmKKMAGYSDDENRADARRL 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  89 RTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPgaggTQRLP---RLIGVGRAKELIY 165
Cdd:PRK05995  89 ADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFL 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 166 TGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAIsngiqvdlhtgLQMEKQAYE--GVIHTKD 243
Cdd:PRK05995 165 TAERFDAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAVRAGKRLV-----------RDVAGRPIDaaLIADTAS 233
                        250       260
                 ....*....|....*....|....*....
gi 446862537 244 RI----------EGLQAFKEKRKPMYKGE 262
Cdd:PRK05995 234 RIalirateearEGVAAFLEKRKPAWRGR 262
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
16-259 6.02e-46

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 155.06  E-value: 6.02e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLK------ERA-----GMNEEQVRHA 84
Cdd:PLN02664  18 VFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAG-DHFCSGIDLKtlnsisEQSssgdrGRSGERLRRK 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  85 VSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELI 164
Cdd:PLN02664  97 IKFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 165 YTGRRISAQEAKEYGLVEFVVPAN-LLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKD 243
Cdd:PLN02664 177 LTGRRFSGSEAKELGLVSRVFGSKeDLDEGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSAMLVSDD 256
                        250
                 ....*....|....*.
gi 446862537 244 RIEGLQAFKEKRKPMY 259
Cdd:PLN02664 257 LNEAVSAQIQKRKPVF 272
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
1-261 1.60e-45

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 153.71  E-value: 1.60e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   1 MLQLQNISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNEEQ 80
Cdd:PRK06210   1 DMAYDAVLYEVADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAG-RGFCAGADMGELQTIDPSD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  81 VRHAVSMIRTTME----------MVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQR 150
Cdd:PRK06210  80 GRRDTDVRPFVGNrrpdyqtryhFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWI 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 151 LPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASN-GPIAVRLAKEAISNGIQVDLHTGLQ 229
Cdd:PRK06210 160 LPRLVGHANALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNvSPASMAVIKRQLYEDAFQTLAEATA 239
                        250       260       270
                 ....*....|....*....|....*....|..
gi 446862537 230 MEKQAYEGVIHTKDRIEGLQAFKEKRKPMYKG 261
Cdd:PRK06210 240 RANREMHESLQRPDFIEGVASFLEKRPPRFPG 271
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
19-262 4.72e-45

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 152.10  E-value: 4.72e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  19 ISLNRARQANSLSLALLDELQTILTQISEDSnARVVIL-TGAGEKAFCAGADLKERAGMNEEQVRHAvSMIRTTMEMVEQ 97
Cdd:PRK11423  17 ITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILrAPSGSKVWSAGHDIHELPSGGRDPLSYD-DPLRQILRMIQK 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  98 LPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE 177
Cdd:PRK11423  95 FPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQRALA 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 178 YGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAI-----SNGIQVDLHTGLQ-MEKQAYEGvihtKDRIEGLQAF 251
Cdd:PRK11423 175 VGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEQLrvlgeAHPMNPDEFERIQgLRRAVYDS----EDYQEGMNAF 250
                        250
                 ....*....|.
gi 446862537 252 KEKRKPMYKGE 262
Cdd:PRK11423 251 LEKRKPVFVGH 261
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
1-207 3.69e-44

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 158.10  E-value: 3.69e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   1 MLQLQNISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTgAGEKAFCAGADLKERAG---MN 77
Cdd:PRK11730   2 IYQGKTLQVDWLEDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLT-SAKDAFIVGADITEFLSlfaAP 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  78 EEQVRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGV 157
Cdd:PRK11730  81 EEELSQWLHFANSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGA 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 446862537 158 GRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAeKIASNGPI 207
Cdd:PRK11730 161 DNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAALALL-KQAIAGKL 209
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
9-259 2.85e-43

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 148.06  E-value: 2.85e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   9 VDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKErAGmneeQVRHAVSMI 88
Cdd:PRK05864  13 VDHPRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAG-RGFSSGADHKS-AG----VVPHVEGLT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  89 RTT-----MEMVE-------QLPQPVIAAINGIALGGGTELSLACDFRIAAESASL-------GLTETTLaiipgaGGTQ 149
Cdd:PRK05864  87 RPTyalrsMELLDdvilalrRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraaginnGLTASEL------GLSY 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 150 RLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQV-DLHTGL 228
Cdd:PRK05864 161 LLPRAIGSSRAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGLDAaSLEAHM 240
                        250       260       270
                 ....*....|....*....|....*....|..
gi 446862537 229 QMEKQAYEGV-IHTKDRIEGLQAFKEKRKPMY 259
Cdd:PRK05864 241 QAEGLGQLFVrLLTANFEEAVAARAEKRPPVF 272
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
18-257 3.96e-43

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 147.35  E-value: 3.96e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  18 KISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKER--AG-MNEEQV-RHAV----SMIR 89
Cdd:PRK07396  25 KITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRgyGGyVDDDGVpRLNVldlqRLIR 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  90 TtmemveqLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRR 169
Cdd:PRK07396 105 T-------CPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQ 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 170 ISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISngIQVDLHTGLQ-MEKQAYEGVIHTKDRIEGL 248
Cdd:PRK07396 178 YDAQEALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALN--ADCDGQAGLQeLAGNATMLFYMTEEAQEGR 255

                 ....*....
gi 446862537 249 QAFKEKRKP 257
Cdd:PRK07396 256 NAFNEKRQP 264
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
12-261 1.71e-42

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 145.88  E-value: 1.71e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEkAFCAGADLKERAG------MNEeqvrhAV 85
Cdd:PRK08258  23 VDDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGG-NFCSGGDVHEIIGpltkmdMPE-----LL 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  86 SMIRTTMEMVEQL---PQPVIAAINGIALGGGTELSLACDFRIAAESASLGL--TETTLAiipGA--GGTQRLPRLIGVG 158
Cdd:PRK08258  97 AFTRMTGDLVKAMracPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFlfTRVGLA---GAdmGACALLPRIIGQG 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 159 RAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIAsNGP-IAVRLAKEAISNGIQVDLHTGLQMEKQAYEG 237
Cdd:PRK08258 174 RASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLA-AGPtFAHGMTKTMLHQEWDMGLEEAIEAEAQAQAI 252
                        250       260
                 ....*....|....*....|....
gi 446862537 238 VIHTKDRIEGLQAFKEKRKPMYKG 261
Cdd:PRK08258 253 CMQTEDFRRAYEAFVAKRKPVFEG 276
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
28-200 2.18e-42

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 153.13  E-value: 2.18e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  28 NSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKERAGMNEEQvrHAVSMIRT---TMEMVEQLPQPVIA 104
Cdd:PRK11154  29 NTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINMLAACKTAQ--EAEALARQgqqLFAEIEALPIPVVA 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 105 AINGIALGGGTELSLACDFRIAAESA--SLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVE 182
Cdd:PRK11154 107 AIHGACLGGGLELALACHYRVCTDDPktVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLRAKQALKLGLVD 186
                        170
                 ....*....|....*...
gi 446862537 183 FVVPANLLEEKAIEIAEK 200
Cdd:PRK11154 187 DVVPHSILLEVAVELAKK 204
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
15-261 8.71e-42

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 143.56  E-value: 8.71e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKaFCAGADLKERAGMNEEQVRHAVSMIRTTMEM 94
Cdd:PRK06563   8 HVLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEH-FTAGLDLADVAPKLAAGGFPFPEGGIDPWGT 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 V-EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQ 173
Cdd:PRK06563  87 VgRRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQ 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 174 EAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRL----AKEAISNGIQVDLhTGLQMEKQAyegVIHTKDRIEGLQ 249
Cdd:PRK06563 167 EALRLGLVQEVVPPGEQLERAIELAERIARAAPLGVQAtlasARAAVREGEAAAA-AQLPPELRP---LFTSEDAKEGVQ 242
                        250
                 ....*....|..
gi 446862537 250 AFKEKRKPMYKG 261
Cdd:PRK06563 243 AFLERRPARFKG 254
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
16-208 8.54e-41

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 140.92  E-value: 8.54e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDsnARVVILTGAGEKaFCAGADLKERAGMNEEQVRHAVSMIRTTMEMV 95
Cdd:PRK08150  12 VATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDH-FCAGLDLSELRERDAGEGMHHSRRWHRVFDKI 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  96 EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 175
Cdd:PRK08150  89 QYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDAQEG 168
                        170       180       190
                 ....*....|....*....|....*....|...
gi 446862537 176 KEYGLVEFVVPANLLEEKAIEIAEKIASNGPIA 208
Cdd:PRK08150 169 ERLGLAQYLVPAGEALDKAMELARRIAQNAPLT 201
PLN02921 PLN02921
naphthoate synthase
15-257 4.03e-40

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 141.08  E-value: 4.03e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGAD--LKERAGMNEEQVRHAVSMIRTTM 92
Cdd:PLN02921  76 GIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDqaVRGKDGYVGPDDAGRLNVLDLQI 155
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  93 EMvEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 172
Cdd:PLN02921 156 QI-RRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYTA 234
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 173 QEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAIsNGIQvDLHTGLQ-MEKQAYEGVIHTKDRIEGLQAF 251
Cdd:PLN02921 235 SEALKMGLVNTVVPLDELEGETVKWCREILRNSPTAIRVLKSAL-NAAD-DGHAGLQeLGGNATLLFYGSEEGNEGRTAY 312

                 ....*.
gi 446862537 252 KEKRKP 257
Cdd:PLN02921 313 LEGRAP 318
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
16-261 4.54e-40

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 139.42  E-value: 4.54e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLK--------ERAGMNEEQVRHAVsM 87
Cdd:PRK07468  15 VATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGwmraqmtaDRATRIEEARRLAM-M 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  88 IRTTMEmveqLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRlIGVGRAKELIYTG 167
Cdd:PRK07468  93 LKALND----LPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFMSA 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 168 RRISAQEAKEYGLVEFVVPANLLEEkAIEiAEKIA--SNGPIAVRLAKE-AISNGIQVDlHTGLQMEKQAYEGVIHTKDR 244
Cdd:PRK07468 168 RLFDAEEAVRLGLLSRVVPAERLDA-AVE-AEVTPylSCAPGAVAAAKAlVRALGAPID-EAVIDATIEALADTWETEEA 244
                        250
                 ....*....|....*..
gi 446862537 245 IEGLQAFKEKRKPMYKG 261
Cdd:PRK07468 245 REGIAAFFDKRAPAWRG 261
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
2-261 3.12e-39

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 137.17  E-value: 3.12e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   2 LQLQNISVDYVTPhVVKISLNRARQANSLSLALLDELQTILTQISEDSN-ARVVILTGAGeKAFCAGADLKERAGMNEE- 79
Cdd:PRK05981   1 MQFKKVTLDFDGG-VAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAeVRCLVLTGAG-RGFCTGANLQGRGSGGREs 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  80 -QVRHAVSMIRTT----MEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRL 154
Cdd:PRK05981  79 dSGGDAGAALETAyhpfLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRL 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 155 IGVGRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQA 234
Cdd:PRK05981 159 VGKARAMELSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPTVALGLIRKLYWDSPENDFEEQLNLEREA 238
                        250       260
                 ....*....|....*....|....*..
gi 446862537 235 YEGVIHTKDRIEGLQAFKEKRKPMYKG 261
Cdd:PRK05981 239 QRIAGKTEDFKEGVGAFLQKRPAQFKG 265
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
16-262 8.53e-39

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 135.68  E-value: 8.53e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMV 95
Cdd:PRK06072  10 YAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPDFAIDLRETFYPIIREIRFS 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  96 EQLpqpVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGRRISAQEA 175
Cdd:PRK06072  89 DKI---YISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQ-RFYEILVLGGEFTAEEA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 176 KEYGLVEfvVPANLLEEkAIEIAEKIaSNGPIAVRLAKEAISNGIQV-DLHTGLQMEK--QAYEGVihTKDRIEGLQAFK 252
Cdd:PRK06072 165 ERWGLLK--ISEDPLSD-AEEMANRI-SNGPFQSYIAAKRMINLVLYnDLEEFLEYESaiQGYLGK--TEDFKEGISSFK 238
                        250
                 ....*....|
gi 446862537 253 EKRKPMYKGE 262
Cdd:PRK06072 239 EKREPKFKGI 248
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
19-216 8.79e-39

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 136.29  E-value: 8.79e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  19 ISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEkAFCAGADLKERAGMNEEQVRHAVSMIR----TTMEM 94
Cdd:PRK09120  21 VTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGD-AWSAGMDLKEYFRETDAQPEILQERIRreayGWWRR 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 174
Cdd:PRK09120 100 LRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGETFTGRK 179
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 446862537 175 AKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAI 216
Cdd:PRK09120 180 AAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGF 221
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
16-203 3.34e-37

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 131.56  E-value: 3.34e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEkAFCAGADLKerAGMNEEQVRHAVS----MIRTT 91
Cdd:PRK08259  13 VTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGG-TFCAGADLK--AVGTGRGNRLHPSgdgpMGPSR 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  92 MemveQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 171
Cdd:PRK08259  90 M----RLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDLILTGRPVD 165
                        170       180       190
                 ....*....|....*....|....*....|..
gi 446862537 172 AQEAKEYGLVEFVVPANLLEEKAIEIAEKIAS 203
Cdd:PRK08259 166 ADEALAIGLANRVVPKGQARAAAEELAAELAA 197
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
7-257 1.44e-36

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 129.71  E-value: 1.44e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   7 ISVDYVTPHVVKISLNRArQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAgmNEEQVRHAVS 86
Cdd:PRK07938   3 ITSTTPEPGIAEVTVDYP-PVNALPSAGWFALADAITAAGADPDTRVVVLRAEG-RGFNAGVDIKELQ--ATPGFTALID 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  87 MIR---TTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTEttlaIIPGA-GGTQRLPRLIGVGRAKE 162
Cdd:PRK07938  79 ANRgcfAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPE----VDRGAlGAATHLQRLVPQHLMRA 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 163 LIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAIsNGIQ-VDLHTGLQMEK----QAYEg 237
Cdd:PRK07938 155 LFFTAATITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKEAL-NGIDpQDVERSYRWEQgftfELNL- 232
                        250       260
                 ....*....|....*....|
gi 446862537 238 vihTKDRIEGLQAFKEKRKP 257
Cdd:PRK07938 233 ---AGVSDEHRDAFVEKRKA 249
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
15-262 1.67e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 130.15  E-value: 1.67e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQIsEDSNARVVILTGAGeKAFCAGADLKER-AGMNEEQVRHAVSMIRTTME 93
Cdd:PRK07659  15 RVATIMLNRPEALNALDEPMLKELLQALKEV-AESSAHIVVLRGNG-RGFSAGGDIKMMlSSNDESKFDGVMNTISEIVV 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  94 MVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQ 173
Cdd:PRK07659  93 TLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSAT 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 174 EAKEYGLVEFVVPANLLEEKAIEIAEKIASngPIAVRLAKEAISNGIQV-DLHTGLQMEKQAYEGVIHTKDRIEGLQAFK 252
Cdd:PRK07659 173 EALDLGLIDEVIGGDFQTAAKQKISEWLQK--PLKAMIETKQIYCELNRsQLEQVLQLEKRAQYAMRQTADHKEGIRAFL 250
                        250
                 ....*....|
gi 446862537 253 EKRKPMYKGE 262
Cdd:PRK07659 251 EKRLPVFKGE 260
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
19-261 4.09e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 128.96  E-value: 4.09e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  19 ISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLK---ERAGMNEEQVRHAVSMIRTTMEMV 95
Cdd:PRK07511  16 LTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAG-GFFCAGGNLNrllENRAKPPSVQAASIDGLHDWIRAI 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  96 EQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 175
Cdd:PRK07511  95 RAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAERL 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 176 KEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRIEGLQAFKEKR 255
Cdd:PRK07511 175 HALGVVNRLAEPGQALAEALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLEKR 254

                 ....*.
gi 446862537 256 KPMYKG 261
Cdd:PRK07511 255 APDYKR 260
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
14-261 8.74e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 125.14  E-value: 8.74e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  14 PHVVKISLNRARQANSLSLALLDELQTILtQISEDSNARVVILTGAGeKAFCAGADLKerAGMNEEQVRHAV-SMIRTtm 92
Cdd:PRK07854   8 GQVLTIELQRPERRNALNAELCEELREAV-RKAVDESARAIVLTGQG-TVFCAGADLS--GDVYADDFPDALiEMLHA-- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  93 emVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISA 172
Cdd:PRK07854  82 --IDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLGAEKLTA 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 173 QEAKEYGLVEFVVPAnlleEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTglQMEKQAYEGVIHTKDRIEGLQAFK 252
Cdd:PRK07854 160 EQALATGMANRIGTL----ADAQAWAAEIAGLAPLALQHAKRVLNDDGAIEEAW--PAHKELFDKAWASQDAIEAQVARI 233

                 ....*....
gi 446862537 253 EKRKPMYKG 261
Cdd:PRK07854 234 EKRPPKFQG 242
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
9-216 9.77e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 126.23  E-value: 9.77e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   9 VDY-VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE---RAGMNEEQVRHA 84
Cdd:PRK08290   6 VRYeVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAG-KHFSAGHDLGSgtpGRDRDPGPDQHP 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  85 VSMIR-TTMEMVEQ------------------LPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLaiipGA 145
Cdd:PRK08290  85 TLWWDgATKPGVEQryarewevylgmcrrwrdLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRM----GI 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446862537 146 GGTQRL--PRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAI 216
Cdd:PRK08290 161 PGVEYFahPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAV 233
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
16-235 1.57e-34

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 131.11  E-value: 1.57e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   16 VVKISLNRARqANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLkeraGMNE-EQVRHAVSMI----RT 90
Cdd:TIGR02441  25 VVKIDSPNSK-VNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADI----QMIAaCKTAQEVTQLsqegQE 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   91 TMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESAS--LGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGR 168
Cdd:TIGR02441 100 MFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGK 179
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446862537  169 RISAQEAKEYGLVEFVV--------PAnllEEKAIEIAEKiasngpIAVRLAKEAISNGIQVDLHTGLQMEKQAY 235
Cdd:TIGR02441 180 KIRADRAKKMGIVDQLVdplgpglkPA---EENTIEYLEE------VAVKFAQGLANGKLSINRDKGLVHKITQY 245
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
5-261 9.32e-33

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 120.51  E-value: 9.32e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   5 QNISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNEE-QVRH 83
Cdd:PRK07327  11 PALRFDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDLALVEEMADDfEVRA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  84 AVsmIRTTMEMVEQL---PQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRA 160
Cdd:PRK07327  90 RV--WREARDLVYNVincDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKA 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 161 KELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQV---DLHTGLQMEKQAYEG 237
Cdd:PRK07327 168 KYYLLLCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAGSQTAIRWTKYALNNWLRMagpTFDTSLALEFMGFSG 247
                        250       260
                 ....*....|....*....|....
gi 446862537 238 vihtKDRIEGLQAFKEKRKPMYKG 261
Cdd:PRK07327 248 ----PDVREGLASLREKRAPDFPG 267
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
15-216 4.25e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 118.29  E-value: 4.25e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEM 94
Cdd:PRK05870  12 GVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG-KAFCAGADLTALGAAPGRPAEDGLRRIYDGFLA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  95 VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQE 174
Cdd:PRK05870  91 VASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEA 170
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 446862537 175 AKEYGLVEFVVPANLLEekAIEIAEKIASNGPIAVRLAKEAI 216
Cdd:PRK05870 171 AVRHGLALMVADDPVAA--ALELAAGPAAAPRELVLATKASM 210
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
12-257 1.01e-30

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 115.89  E-value: 1.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAG--EK----AFCAGADLKER-------AGMNE 78
Cdd:PRK08321  31 VDQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTGNGpsPKdggwAFCSGGDQRIRgrdgyqyAEGDE 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  79 EQVRHAVSMIRTTMEMVEQL----PQPVIAAINGIALGGGTELSLACDFRIA-AESASLGLTETTLAIIPGAGGTQRLPR 153
Cdd:PRK08321 111 ADTVDPARAGRLHILEVQRLirfmPKVVIAVVPGWAAGGGHSLHVVCDLTLAsREHARFKQTDADVGSFDGGYGSAYLAR 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 154 LIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEA---ISNGIqvdlhtglqM 230
Cdd:PRK08321 191 QVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAREINGKSPTAMRMLKYAfnlTDDGL---------V 261
                        250       260       270
                 ....*....|....*....|....*....|..
gi 446862537 231 EKQAYEG-----VIHTKDRIEGLQAFKEKRKP 257
Cdd:PRK08321 262 GQQLFAGeatrlAYMTDEAQEGRDAFLEKRDP 293
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
19-216 1.08e-30

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 116.42  E-value: 1.08e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   19 ISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKE-RAGMNEEQVRHAVSMIRTTMEMVEQ 97
Cdd:pfam16113   4 ITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRAlYEAAKAGGGEAGRDFFREEYRLNYL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   98 L---PQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIG-VGRakeliY---TGRRI 170
Cdd:pfam16113  84 IatyPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGeLGL-----YlalTGARL 158
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 446862537  171 SAQEAKEYGLVEFVVPANLLEekaiEIAEKIASNGPIAVRLAKEAI 216
Cdd:pfam16113 159 NGADALAAGLATHYVPSARLP----ALEEALAALDWSDPADVDAVL 200
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
12-203 3.14e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 112.06  E-value: 3.14e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  12 VTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLK--------ERAGMNEEQVRH 83
Cdd:PRK08272  16 VTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAG-KGFCAGYDLSayaegsssGGGGGAYPGKRQ 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  84 AVS---------------MIRTTmEMVEQL---PQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGA 145
Cdd:PRK08272  95 AVNhlpddpwdpmidyqmMSRFV-RGFMSLwhaHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVWGVPAT 173
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446862537 146 G-GTQRLprliGVGRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIAS 203
Cdd:PRK08272 174 GmWAYRL----GPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAA 228
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
28-217 1.27e-28

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 108.39  E-value: 1.27e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  28 NSLSLALLDELQTILTQISEDSNARVVILTGaGEKAFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIAAIN 107
Cdd:PRK05869  29 NALTRQVYREIVAAANELGRRDDVAAVILYG-GHEIFSAGDDMPELRTLSAQEADTAARVRQQAVDAVAAIPKPTVAAIT 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 108 GIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPA 187
Cdd:PRK05869 108 GYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDEMVAP 187
                        170       180       190
                 ....*....|....*....|....*....|
gi 446862537 188 NLLEEKAIEIAEKIASNGPIAVRLAKEAIS 217
Cdd:PRK05869 188 DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
16-181 2.81e-25

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 100.53  E-value: 2.81e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKERAGMNEEQVRHAVSMIR---TTM 92
Cdd:PRK07827  16 VATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTG-GTFCAGADLSEAGGGGGDPYDAAVARARemtALL 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  93 EMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLigVGRAKELIY-TGRRIS 171
Cdd:PRK07827  95 RAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRL--SPRAAARYYlTGEKFG 172
                        170
                 ....*....|
gi 446862537 172 AQEAKEYGLV 181
Cdd:PRK07827 173 AAEAARIGLV 182
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
5-256 1.13e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 98.66  E-value: 1.13e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   5 QNISVDyVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE-RAGMNEEQVRH 83
Cdd:PRK07260   2 EHIIYE-VEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANG-KVFSVGGDLVEmKRAVDEDDVQS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  84 AVSMIRTTMEM---VEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRA 160
Cdd:PRK07260  80 LVKIAELVNEIsfaIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRA 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 161 KELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIH 240
Cdd:PRK07260 160 THLAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLLKKLRRGSSNSYAAIKSLVWESFFKGWEDYAKLELALQESLAF 239
                        250
                 ....*....|....*.
gi 446862537 241 TKDRIEGLQAFKEKRK 256
Cdd:PRK07260 240 KEDFKEGVRAFSERRR 255
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
21-262 1.43e-23

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 96.03  E-value: 1.43e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  21 LNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADL---KERAGMNEEQVRHAVSMIRTTMEMVEQ 97
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRG-RHFSAGADLawmQQSADLDYNTNLDDARELAELMYNLYR 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  98 LPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPgAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE 177
Cdd:PRK05674 100 LKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAP-AVISPFVVKAIGERAARRYALTAERFDGRRARE 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 178 YGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTK-DRIEGLQAFKEKRK 256
Cdd:PRK05674 179 LGLLAESYPAAELEAQVEAWIANLLLNSPQALRASKDLLREVGDGELSPALRRYCENAIARIRVSaEGQEGLRAFLEKRT 258

                 ....*.
gi 446862537 257 PMYKGE 262
Cdd:PRK05674 259 PAWQTD 264
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
19-217 3.31e-23

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 96.43  E-value: 3.31e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  19 ISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLKE-----RAGMNEEQVR---------HA 84
Cdd:PRK05617  16 ITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRAlyeaaRAGDPLAADRffreeyrlnAL 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  85 VSmirttmemveQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIG-VGRAKEL 163
Cdd:PRK05617  96 IA----------RYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGaLGTYLAL 165
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446862537 164 iyTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAIS 217
Cdd:PRK05617 166 --TGARISAADALYAGLADHFVPSADLPALLDALISLRWDSGADVVDAALAAFA 217
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
14-216 6.12e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 91.39  E-value: 6.12e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  14 PHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAgEKAFCAGADLKE--RAGMNEEQVRHAVSMIRTT 91
Cdd:PRK06023  14 PGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGT-EGCFSAGNDMQDflAAAMGGTSFGSEILDFLIA 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  92 MEMVEQlpqPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRIS 171
Cdd:PRK06023  93 LAEAEK---PIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFS 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446862537 172 AQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAI 216
Cdd:PRK06023 170 AEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKPPQALQIARDLM 214
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
7-248 2.47e-21

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 89.64  E-value: 2.47e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   7 ISVDYVTPHVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGEkAFCAGAdlkERAGMNEEQvRHAVS 86
Cdd:PRK07110   6 VELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPN-YFATGG---TQEGLLSLQ-TGKGT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  87 MIRTTM-EMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIY 165
Cdd:PRK07110  81 FTEANLySLALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 166 TGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIH---TK 242
Cdd:PRK07110 161 TARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLAEKPRHSLVLLKDHLVADRRRRLPEVIEQEVAMHEKTFHqpeVK 240

                 ....*.
gi 446862537 243 DRIEGL 248
Cdd:PRK07110 241 RRIESL 246
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
28-215 9.92e-19

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 83.01  E-value: 9.92e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  28 NSLSLALLDELQTILTQISEDSNARVVILTGAGEK-AFCAGADLKERAGMNEEQVRHAVSMIRTTMEMVEQLPQPV--IA 104
Cdd:PLN03214  33 NSMTLAMWRSLDDALTALENDPTVRGVVFASGLRRdVFTAGNDIAELYAPKTSAARYAEFWLTQTTFLVRLLRSRLatVC 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 105 AINGIALGGGTELSLACDFRIAAESASLGLTETTLAI-IPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEF 183
Cdd:PLN03214 113 AIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDE 192
                        170       180       190
                 ....*....|....*....|....*....|..
gi 446862537 184 VVPANLLEEKAIEIAEKiASNGPIAVRLAKEA 215
Cdd:PLN03214 193 VVPAAALMEAAASAMER-ALKLPSAARAATKA 223
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
19-206 3.77e-18

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 82.84  E-value: 3.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  19 ISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE----------RAGMNEEQVRHAVSMI 88
Cdd:PLN02988  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAvvrdieqgnwRLGANFFSDEYMLNYV 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  89 RTTMEMVEqlpqpvIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGR 168
Cdd:PLN02988 101 MATYSKAQ------VSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGF-FGEYVGLTGA 173
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446862537 169 RISAQEAKEYGLVEFVVPANLLEEKAIEIAeKIASNGP 206
Cdd:PLN02988 174 RLDGAEMLACGLATHFVPSTRLTALEADLC-RIGSNDP 210
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
15-246 2.19e-17

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 80.61  E-value: 2.19e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  15 HVVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE--RAGMNEEQVRHAVSMIRTTM 92
Cdd:PLN02874  20 RVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMfyDGRESDDSCLEVVYRMYWLC 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  93 EMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIG-VGraKELIYTGRRIS 171
Cdd:PLN02874  99 YHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGhLG--EYLALTGARLN 176
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446862537 172 AQEAKEYGLVEFVVPANLLEEKAIEIAEkIASNGPIAVRLAKEAISNGIQVDLHTGLQmeKQAYEGVIHTKDRIE 246
Cdd:PLN02874 177 GKEMVACGLATHFVPSEKLPELEKRLLN-LNSGDESAVQEAIEEFSKDVQADEDSILN--KQSWINECFSKDTVE 248
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
16-236 2.45e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 76.92  E-value: 2.45e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADL---------------KERAGMNEEQ 80
Cdd:PRK12478  15 VATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGYDFgggfqhwgeammtdgRWDPGKDFAM 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  81 VRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGlteTTLAIIPGAGGTQRLPRLIGVGRA 160
Cdd:PRK12478  94 VTARETGPTQKFMAIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIG---TPYSRMWGAYLTGMWLYRLSLAKV 170
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446862537 161 KELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNgPIAVRLAKEAISNgiqvdlhtglqmekQAYE 236
Cdd:PRK12478 171 KWHSLTGRPLTGVQAAEAELINEAVPFERLEARVAEVATELARI-PLSQLQAQKLIVN--------------QAYE 231
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
1-214 3.74e-15

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 73.41  E-value: 3.74e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   1 MLQLQNISVDYVTPHVVKISLNRARQANSLSLALLDE---LQTILTQISEDSNARV--VILTGAGEKAFCAGADLKE--- 72
Cdd:PRK08788  11 AGELSQLRVYYEEERNVMWMYMRAQPRPCFNLELLDDimnLQRAIRQRLDDSGLPVdfWVLASDVPGVFNLGGDLALfae 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  73 --RAGMNEEQVRHAVSMIRTTMEMVEQLPQPV--IAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGT 148
Cdd:PRK08788  91 liRAGDRDALLAYARACVDGVHAFHRGFGAGAisIALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAY 170
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446862537 149 QRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIA--SNGPIAVRLAKE 214
Cdd:PRK08788 171 SFLARRVGPKLAEELILSGKLYTAEELHDMGLVDVLVEDGQGEAAVRTFIRKSKrkLNGWRAMLRARR 238
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
5-182 1.08e-14

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 71.64  E-value: 1.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537   5 QNISVDYvTPHVVKISLNRARQANSLSLALLDELQTILTQISEDsnARVVILTGAGEkAFCAGADLK---ERAGMNEEQV 81
Cdd:PRK07112   4 QTIRVRQ-QGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHA--ATIVVLEGLPE-VFCFGADFSaiaEKPDAGRADL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  82 RHAVSMIRTTMEMVEQlPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPgAGGTQRLPRLIGVGRAK 161
Cdd:PRK07112  80 IDAEPLYDLWHRLATG-PYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP-ACVLPFLIRRIGTQKAH 157
                        170       180
                 ....*....|....*....|.
gi 446862537 162 ELIYTGRRISAQEAKEYGLVE 182
Cdd:PRK07112 158 YMTLMTQPVTAQQAFSWGLVD 178
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
21-180 3.49e-14

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 71.64  E-value: 3.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  21 LNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGADLKE----RAGMNEEQVRHAVSMIRTTMEMVE 96
Cdd:PLN02157  52 LNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSlyhlRKRGSPDAIREFFSSLYSFIYLLG 130
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  97 QLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLigVGRAKELI-YTGRRISAQEA 175
Cdd:PLN02157 131 TYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHL--PGRLGEYLgLTGLKLSGAEM 208

                 ....*
gi 446862537 176 KEYGL 180
Cdd:PLN02157 209 LACGL 213
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
21-180 1.68e-13

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 69.62  E-value: 1.68e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  21 LNRARQANSLSLALLDELQTILTQISEDSNARVVILTGAGeKAFCAGAD-LKERAGMNEEQVRHAVSMIRTTMEMVEQLP 99
Cdd:PLN02851  57 LNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSGADvVSLYHLINEGNVEECKLFFENLYKFVYLQG 135
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 100 ---QPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVgRAKELIYTGRRISAQEAK 176
Cdd:PLN02851 136 tylKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGY-LGEYLALTGQKLNGVEMI 214

                 ....
gi 446862537 177 EYGL 180
Cdd:PLN02851 215 ACGL 218
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
16-227 2.70e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 64.61  E-value: 2.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  16 VVKISLNRARqANSLSLALLDELQTILTQISEDSnaRVVILTGAgEKAFCAGADLKERAGMNEEqvrhAVSMIRTTMEMV 95
Cdd:PRK06213  13 VATITLDDGK-VNALSPAMIDALNAALDQAEDDR--AVVVITGQ-PGIFSGGFDLKVMTSGAQA----AIALLTAGSTLA 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  96 EQL---PQPVIAAINGIALGGGTELSLACDFRIAAESA-SLGLTETTLAI-IPGAG---GTQRLPRlIGVGRAkelIYTG 167
Cdd:PRK06213  85 RRLlshPKPVIVACTGHAIAKGAFLLLSADYRIGVHGPfKIGLNEVAIGMtMPHAAielARDRLTP-SAFQRA---VINA 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446862537 168 RRISAQEAKEYGLVEFVVPANLLEEKAIEIAEKIASNGPIAVRLAK--------EAISNGIQVDL-HTG 227
Cdd:PRK06213 161 EMFDPEEAVAAGFLDEVVPPEQLLARAQAAARELAGLNMGAHAATKlkvraaalEAIRAAIEGDAaEFG 229
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
30-205 1.51e-09

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 56.65  E-value: 1.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537  30 LSLALLDELQTILTQISEDSNARVVILTGAGEKAFCAGADLK--ERAGMNEEQVRHAVSMIRTTMEMVEQLPQPVIAAIN 107
Cdd:PLN02267  23 LNPTLIDSIRSALRQVKSQATPGSVLITTAEGKFFSNGFDLAwaQAAGSAPSRLHLMVAKLRPLVADLISLPMPTIAAVT 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446862537 108 GIALGGGTELSLACDFRIA-AESASLGLTETTLAIIPGAGGTQRLPRLIGVGRA-KELIYTGRRISAQEAKEYGLVEFVV 185
Cdd:PLN02267 103 GHASAAGFILALSHDYVLMrKDRGVLYMSEVDIGLPLPDYFMALLRAKIGSPAArRDVLLRAAKLTAEEAVEMGIVDSAH 182
                        170       180
                 ....*....|....*....|.
gi 446862537 186 P-ANLLEEKAIEIAEKIASNG 205
Cdd:PLN02267 183 DsAEETVEAAVRLGEELAARK 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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