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Conserved domains on  [gi|446892528|ref|WP_000969784|]
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MULTISPECIES: 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase PaaG [Enterobacteriaceae]

Protein Classification

enoyl-CoA hydratase( domain architecture ID 10793017)

enoyl-CoA hydratase such as 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase, which catalyzes the reversible conversion of the epoxide to 2-oxepin-2(3H)-ylideneacetyl-CoA (oxepin-CoA)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-262 2.10e-163

enoyl-CoA hydratase; Provisional


:

Pssm-ID: 236163  Cd Length: 262  Bit Score: 452.83  E-value: 2.10e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVErDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDL 80
Cdd:PRK08140   2 MYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAGRGFCAGQDLADRDVTPGGAMPDL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA 160
Cdd:PRK08140  81 GESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGR 240
Cdd:PRK08140 161 LGLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGR 240
                        250       260
                 ....*....|....*....|..
gi 446892528 241 SADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK08140 241 SADYAEGVSAFLEKRAPRFTGR 262
 
Name Accession Description Interval E-value
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-262 2.10e-163

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 452.83  E-value: 2.10e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVErDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDL 80
Cdd:PRK08140   2 MYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAGRGFCAGQDLADRDVTPGGAMPDL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA 160
Cdd:PRK08140  81 GESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGR 240
Cdd:PRK08140 161 LGLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGR 240
                        250       260
                 ....*....|....*....|..
gi 446892528 241 SADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK08140 241 SADYAEGVSAFLEKRAPRFTGR 262
PaaB1 TIGR02280
phenylacetate degradation probable enoyl-CoA hydratase paaB; This family of proteins are found ...
5-262 2.53e-160

phenylacetate degradation probable enoyl-CoA hydratase paaB; This family of proteins are found within apparent operons for the degradation of phenylacetic acid. These proteins contain the enoyl-CoA hydratase domain as detected by pfam00378. This activity is consistent with current hypotheses for the degradation pathway, which involve the ligation of phenylacetate with coenzyme A (paaF), hydroxylation (paaGHIJK), ring-opening (paaN) and degradation of the resulting fatty acid-like compound to a Krebs cycle intermediate (paaABCDE).


Pssm-ID: 274065  Cd Length: 257  Bit Score: 445.07  E-value: 2.53e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528    5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPtGPAPDLGMSV 84
Cdd:TIGR02280   1 ILSHLEKGVATLTLNRPDKLNSFNAEMHAELAEALKRVERDDTARALLLTGAGRGFCAGQDLSDRNVTP-GPAPDLGMTV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   85 ERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLA 164
Cdd:TIGR02280  80 ERFYNPLVRRLAALPKPVICAVNGVAAGAGANLALAGDIVIAARSAKFIQAFSKLGLIPDSGGTWLLPRLVGRARAMGLA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  165 LLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADY 244
Cdd:TIGR02280 160 LLGNKLSAEQAHEWGLIWQVVDDATLMDEAQALARHLATQPTRGLGLIKRAIQAAETNSLDTQLDLERDLQREAGRSADY 239
                         250
                  ....*....|....*...
gi 446892528  245 REGVSAFLAKRSPQFTGK 262
Cdd:TIGR02280 240 AEGVSAFLDKRSPQFTGK 257
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
5-255 6.82e-86

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 256.25  E-value: 6.82e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTgpaPDLGMSV 84
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAAD---PEEARAF 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  85 ERFYNPLVRRLAKLPKPVI-----------------CavngvaagagatlalggDIVIAARSAKFVMAFSKLGLIPDCGG 147
Cdd:COG1024   78 ARGLQRLFRALRRLPKPVIaavngaalggglelalaC-----------------DLRIAAEDARFGLPEVRLGLIPGGGG 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 148 TWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQ 227
Cdd:COG1024  141 TQRLPRLVGLARAKELLLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEA 220
                        250       260
                 ....*....|....*....|....*...
gi 446892528 228 LDLERDYQRLAGRSADYREGVSAFLAKR 255
Cdd:COG1024  221 LELEAEAFAELFASEDAREGIAAFLEKR 248
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
5-201 1.51e-57

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 181.99  E-value: 1.51e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDrnVDPTGPAPDLGMSV 84
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKE--LAALSDAGEEARAF 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  85 ERFYNPLVRRLAKLPKPVI-----------------CavngvaagagatlalggDIVIAARSAKFVMAFSKLGLIPDCGG 147
Cdd:cd06558   79 IRELQELLRALLRLPKPVIaavngaalggglelalaC-----------------DIRIAAEDAKFGLPEVKLGLVPGGGG 141
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446892528 148 TWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHL 201
Cdd:cd06558  142 TQRLPRLVGPARARELLLTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
10-262 5.18e-57

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 182.56  E-value: 5.18e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   10 EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVErfyn 89
Cdd:pfam00378   3 NAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENVL---- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   90 PLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQ 169
Cdd:pfam00378  79 DLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRR 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  170 LSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREGVS 249
Cdd:pfam00378 159 ISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQ 238
                         250
                  ....*....|...
gi 446892528  250 AFLAKRSPQFTGK 262
Cdd:pfam00378 239 AFLEKRKPPWEDQ 251
 
Name Accession Description Interval E-value
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-262 2.10e-163

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 452.83  E-value: 2.10e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVErDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDL 80
Cdd:PRK08140   2 MYETILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAGRGFCAGQDLADRDVTPGGAMPDL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA 160
Cdd:PRK08140  81 GESIETFYNPLVRRLRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGR 240
Cdd:PRK08140 161 LGLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGR 240
                        250       260
                 ....*....|....*....|..
gi 446892528 241 SADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK08140 241 SADYAEGVSAFLEKRAPRFTGR 262
PaaB1 TIGR02280
phenylacetate degradation probable enoyl-CoA hydratase paaB; This family of proteins are found ...
5-262 2.53e-160

phenylacetate degradation probable enoyl-CoA hydratase paaB; This family of proteins are found within apparent operons for the degradation of phenylacetic acid. These proteins contain the enoyl-CoA hydratase domain as detected by pfam00378. This activity is consistent with current hypotheses for the degradation pathway, which involve the ligation of phenylacetate with coenzyme A (paaF), hydroxylation (paaGHIJK), ring-opening (paaN) and degradation of the resulting fatty acid-like compound to a Krebs cycle intermediate (paaABCDE).


Pssm-ID: 274065  Cd Length: 257  Bit Score: 445.07  E-value: 2.53e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528    5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPtGPAPDLGMSV 84
Cdd:TIGR02280   1 ILSHLEKGVATLTLNRPDKLNSFNAEMHAELAEALKRVERDDTARALLLTGAGRGFCAGQDLSDRNVTP-GPAPDLGMTV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   85 ERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLA 164
Cdd:TIGR02280  80 ERFYNPLVRRLAALPKPVICAVNGVAAGAGANLALAGDIVIAARSAKFIQAFSKLGLIPDSGGTWLLPRLVGRARAMGLA 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  165 LLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADY 244
Cdd:TIGR02280 160 LLGNKLSAEQAHEWGLIWQVVDDATLMDEAQALARHLATQPTRGLGLIKRAIQAAETNSLDTQLDLERDLQREAGRSADY 239
                         250
                  ....*....|....*...
gi 446892528  245 REGVSAFLAKRSPQFTGK 262
Cdd:TIGR02280 240 AEGVSAFLDKRSPQFTGK 257
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
5-255 6.82e-86

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 256.25  E-value: 6.82e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTgpaPDLGMSV 84
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKELAAAAD---PEEARAF 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  85 ERFYNPLVRRLAKLPKPVI-----------------CavngvaagagatlalggDIVIAARSAKFVMAFSKLGLIPDCGG 147
Cdd:COG1024   78 ARGLQRLFRALRRLPKPVIaavngaalggglelalaC-----------------DLRIAAEDARFGLPEVRLGLIPGGGG 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 148 TWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQ 227
Cdd:COG1024  141 TQRLPRLVGLARAKELLLTGRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEA 220
                        250       260
                 ....*....|....*....|....*...
gi 446892528 228 LDLERDYQRLAGRSADYREGVSAFLAKR 255
Cdd:COG1024  221 LELEAEAFAELFASEDAREGIAAFLEKR 248
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
9-262 1.91e-84

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 253.12  E-value: 1.91e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   9 VEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVE-RDDTIRCLLLTGAGRGFCAGQDLNDRNVDP--TGPAPDLGMSVE 85
Cdd:PRK05981  10 FDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEdGKAEVRCLVLTGAGRGFCTGANLQGRGSGGreSDSGGDAGAALE 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  86 RFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLAL 165
Cdd:PRK05981  90 TAYHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSL 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 166 LGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYR 245
Cdd:PRK05981 170 LGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPTVALGLIRKLYWDSPENDFEEQLNLEREAQRIAGKTEDFK 249
                        250
                 ....*....|....*..
gi 446892528 246 EGVSAFLAKRSPQFTGK 262
Cdd:PRK05981 250 EGVGAFLQKRPAQFKGR 266
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
1-262 2.29e-80

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 242.47  E-value: 2.29e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDL 80
Cdd:PRK06688   3 MVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDFPKAPPKPPDEL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 gMSVERFynplVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA 160
Cdd:PRK06688  83 -APVNRF----LRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARA 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGR 240
Cdd:PRK06688 158 AEMLLLGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLR 237
                        250       260
                 ....*....|....*....|..
gi 446892528 241 SADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK06688 238 TPDFREGATAFIEKRKPDFTGF 259
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-262 4.11e-62

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 195.96  E-value: 4.11e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFND-EMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAG---QDLNDRNVDPTGP 76
Cdd:PRK09245   1 MTDFLLVERDGHIVTLTMNRPETRNALSDnDAVDALVAACAAINADRSVRAVILTGAGTAFSSGgnvKDMRARVGAFGGS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  77 APDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAG 156
Cdd:PRK09245  81 PADIRQGYRHGIQRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 157 RARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQR 236
Cdd:PRK09245 161 MARAAEMAFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAAYQA 240
                        250       260
                 ....*....|....*....|....*.
gi 446892528 237 LAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK09245 241 LAHHTADHREAVDAFLEKRPPVFTGR 266
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
5-201 1.51e-57

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 181.99  E-value: 1.51e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDrnVDPTGPAPDLGMSV 84
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAGKAFCAGADLKE--LAALSDAGEEARAF 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  85 ERFYNPLVRRLAKLPKPVI-----------------CavngvaagagatlalggDIVIAARSAKFVMAFSKLGLIPDCGG 147
Cdd:cd06558   79 IRELQELLRALLRLPKPVIaavngaalggglelalaC-----------------DIRIAAEDAKFGLPEVKLGLVPGGGG 141
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446892528 148 TWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHL 201
Cdd:cd06558  142 TQRLPRLVGPARARELLLTGRRISAEEALELGLVDEVVPDEELLAAALELARRL 195
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
1-261 1.61e-57

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 184.04  E-value: 1.61e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLN----DRNVDPTgp 76
Cdd:PRK07511   1 MSAELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGGFFCAGGNLNrlleNRAKPPS-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  77 apDLGMSVERFYNpLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAG 156
Cdd:PRK07511  79 --VQAASIDGLHD-WIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALP 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 157 RARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQR 236
Cdd:PRK07511 156 RQLATELLLEGKPISAERLHALGVVNRLAEPGQALAEALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFV 235
                        250       260
                 ....*....|....*....|....*
gi 446892528 237 LAGRSADYREGVSAFLAKRSPQFTG 261
Cdd:PRK07511 236 ASLHHADALEGIAAFLEKRAPDYKR 260
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
10-262 5.18e-57

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 182.56  E-value: 5.18e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   10 EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVErfyn 89
Cdd:pfam00378   3 NAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQALYRENVL---- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   90 PLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQ 169
Cdd:pfam00378  79 DLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRR 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  170 LSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREGVS 249
Cdd:pfam00378 159 ISAQEALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQ 238
                         250
                  ....*....|...
gi 446892528  250 AFLAKRSPQFTGK 262
Cdd:pfam00378 239 AFLEKRKPPWEDQ 251
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
1-262 4.40e-53

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 172.93  E-value: 4.40e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDrnVDPTGPAPDL 80
Cdd:PRK08138   6 TDVVLLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKE--FATAGAIEMY 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSVERFYNPLvrrlAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA 160
Cdd:PRK08138  84 LRHTERYWEAI----AQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKA 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGR 240
Cdd:PRK08138 160 MRMALTGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFD 239
                        250       260
                 ....*....|....*....|..
gi 446892528 241 SADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK08138 240 SEDQKEGMDAFLEKRKPAYKGK 261
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
2-262 3.37e-50

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 166.33  E-value: 3.37e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLN------DRNVDPTg 75
Cdd:PRK08260   3 YETIRYDVADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLSaggntfDLDAPRT- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  76 PAPDLGMSVERFYNPLVR--------RLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGG 147
Cdd:PRK08260  82 PVEADEEDRADPSDDGVRdgggrvtlRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAAS 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 148 TWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQ--PTfGLGLIKQAI--NSAETNT 223
Cdd:PRK08260 162 SWFLPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIADNtsPV-SVALTRQMMwrMAGADHP 240
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 446892528 224 LDTQLDLERDYQRlAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK08260 241 MEAHRVDSRAIYS-RGRSGDGKEGVSSFLEKRPAVFPGK 278
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
1-262 4.92e-50

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 165.26  E-value: 4.92e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEF--ILSHV-EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND-RNVDPTGP 76
Cdd:PRK06210   1 DMAYdaVLYEVaDSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGElQTIDPSDG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  77 A-----PDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLL 151
Cdd:PRK06210  81 RrdtdvRPFVGNRRPDYQTRYHFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWIL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 152 PRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQ--PTfGLGLIKQAINSAETNTL-DTQL 228
Cdd:PRK06210 161 PRLVGHANALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNvsPA-SMAVIKRQLYEDAFQTLaEATA 239
                        250       260       270
                 ....*....|....*....|....*....|....
gi 446892528 229 DLERDyQRLAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK06210 240 RANRE-MHESLQRPDFIEGVASFLEKRPPRFPGL 272
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
12-261 6.43e-50

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 164.18  E-value: 6.43e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  12 GVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRnvdptgpAPDLGMSVERFYNPL 91
Cdd:PRK06072   9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEF-------APDFAIDLRETFYPI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  92 VRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGrARAMGLALLGNQLS 171
Cdd:PRK06072  82 IREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTG-QRFYEILVLGGEFT 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 172 AEQAHEWGMIwQVVDDeTLADtAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREGVSAF 251
Cdd:PRK06072 161 AEEAERWGLL-KISED-PLSD-AEEMANRISNGPFQSYIAAKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGISSF 237
                        250
                 ....*....|
gi 446892528 252 LAKRSPQFTG 261
Cdd:PRK06072 238 KEKREPKFKG 247
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
8-261 6.43e-47

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 157.44  E-value: 6.43e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   8 HVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDrnvdPTGP-----APDLgM 82
Cdd:PRK08258  22 EVDDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGNFCSGGDVHE----IIGPltkmdMPEL-L 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  83 SVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLI-PDCGGTWLLPRVAGRARAM 161
Cdd:PRK08258  97 AFTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACALLPRIIGQGRAS 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 162 GLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRS 241
Cdd:PRK08258 177 ELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAGPTFAHGMTKTMLHQEWDMGLEEAIEAEAQAQAICMQT 256
                        250       260
                 ....*....|....*....|
gi 446892528 242 ADYREGVSAFLAKRSPQFTG 261
Cdd:PRK08258 257 EDFRRAYEAFVAKRKPVFEG 276
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
2-262 6.12e-46

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 154.15  E-value: 6.12e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRnvdptgPAPDLG 81
Cdd:PRK09674   1 MSELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEM------AEKDLA 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  82 MSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAM 161
Cdd:PRK09674  75 ATLNDPRPQLWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLAS 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 162 GLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRS 241
Cdd:PRK09674 155 QMVLTGESITAQQAQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAAT 234
                        250       260
                 ....*....|....*....|.
gi 446892528 242 ADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK09674 235 EDRHEGISAFLEKRTPDFKGR 255
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
2-262 5.20e-44

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 149.40  E-value: 5.20e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERlNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND-----RNVDPTGP 76
Cdd:PRK07658   1 MKFLSVRVEDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEftsvtEAEQATEL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  77 ApDLGMSVerfynplVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAG 156
Cdd:PRK07658  80 A-QLGQVT-------FERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVG 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 157 RARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQR 236
Cdd:PRK07658 152 KAKALEMMLTSEPITGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFG 231
                        250       260
                 ....*....|....*....|....*.
gi 446892528 237 LAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK07658 232 EVFTSEDAKEGVQAFLEKRKPSFSGK 257
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
2-255 3.79e-43

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 147.19  E-value: 3.79e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND--RNVDptgpAPD 79
Cdd:PRK07260   1 FEHIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGKVFSVGGDLVEmkRAVD----EDD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  80 LGMSVE--RFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGR 157
Cdd:PRK07260  77 VQSLVKiaELVNEISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGL 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 158 ARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRL 237
Cdd:PRK07260 157 NRATHLAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLLKKLRRGSSNSYAAIKSLVWESFFKGWEDYAKLELALQES 236
                        250
                 ....*....|....*...
gi 446892528 238 AGRSADYREGVSAFLAKR 255
Cdd:PRK07260 237 LAFKEDFKEGVRAFSERR 254
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
1-262 1.63e-41

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 142.87  E-value: 1.63e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDL------NDRNVDP 73
Cdd:PRK06494   2 ALPFSTVERKGHVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGdKAFSAGNDLkeqaagGKRGWPE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  74 TGpapdLGMSVERFynplvrrlaKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPR 153
Cdd:PRK06494  82 SG----FGGLTSRF---------DLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPR 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 154 VAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERD 233
Cdd:PRK06494 149 QIGLKRAMGMILTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQAVYRGLEVSLEEAITAQRD 228
                        250       260       270
                 ....*....|....*....|....*....|..
gi 446892528 234 Y---QRLAgRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK06494 229 YpavEARR-ASQDYIEGPKAFAEKRPPRWKGR 259
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
2-262 2.73e-41

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 142.48  E-value: 2.73e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDtIRCLLLTGAGRGFCAGQDLNdrnvdpTGPAPDLG 81
Cdd:PRK07659   5 MESVVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESS-AHIVVLRGNGRGFSAGGDIK------MMLSSNDE 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  82 MSVERFYNPL---VRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRA 158
Cdd:PRK07659  78 SKFDGVMNTIseiVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGEN 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 159 RAMGLALLGNQLSAEQAHEWGMIWQVVDDEtLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLA 238
Cdd:PRK07659 158 KAKQIIWEGKKLSATEALDLGLIDEVIGGD-FQTAAKQKISEWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKRAQYAM 236
                        250       260
                 ....*....|....*....|....
gi 446892528 239 GRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK07659 237 RQTADHKEGIRAFLEKRLPVFKGE 260
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
1-262 1.38e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 140.64  E-value: 1.38e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFIL-SHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLNDRnvdptgpap 78
Cdd:PRK07657   1 MLQNISvDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGeKAFCAGADLKER--------- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  79 dLGMSVE--RFYNPLVRR----LAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLP 152
Cdd:PRK07657  72 -AGMNEEqvRHAVSLIRTtmemVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLP 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 153 RVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLER 232
Cdd:PRK07657 151 RLIGVGRAKELIYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEK 230
                        250       260       270
                 ....*....|....*....|....*....|
gi 446892528 233 DYQRLAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK07657 231 QAYEGTIPTKDRLEGLQAFKEKRKPMYKGE 260
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
1-254 1.77e-39

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 137.55  E-value: 1.77e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDl 80
Cdd:PRK05870   1 MMDPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTALGAAPGRPAED- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 gmSVERFYNPLVRrLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA 160
Cdd:PRK05870  80 --GLRRIYDGFLA-VASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVA 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDDetLADTAQQLARHLATQPTFGLGLIKQAINSAETN-TLDTQLDLERDYQRLAG 239
Cdd:PRK05870 157 RAALLFGMRFDAEAAVRHGLALMVADD--PVAAALELAAGPAAAPRELVLATKASMRATASLaQHAAAVEFELGPQAASV 234
                        250
                 ....*....|....*
gi 446892528 240 RSADYREGVSAFLAK 254
Cdd:PRK05870 235 QSPEFAARLAAAQRR 249
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
1-259 5.06e-38

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 134.12  E-value: 5.06e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLNDRNvDPTGPAPD 79
Cdd:PRK05980   1 MTDTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGdRAFSAGADIHEFS-ASVAAGAD 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  80 LGMS--VERfYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGR 157
Cdd:PRK05980  80 VALRdfVRR-GQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGR 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 158 ARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERD-YQR 236
Cdd:PRK05980 159 KRALELLLTGDAFSAERALEIGLVNAVVPHEELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEqFAR 238
                        250       260
                 ....*....|....*....|...
gi 446892528 237 LAGrSADYREGVSAFLAKRSPQF 259
Cdd:PRK05980 239 MAG-SADLREGLAAWIERRRPAY 260
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
1-262 7.19e-38

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 133.19  E-value: 7.19e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND--RNVDPTGPAP 78
Cdd:PRK08252   1 MSDEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAfaRGERPSIPGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  79 DLGMSVERfynplvrrlaKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRA 158
Cdd:PRK08252  81 GFGGLTER----------PPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYH 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 159 RAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLA 238
Cdd:PRK08252 151 IAMELALTGDMLTAERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPV 230
                        250       260
                 ....*....|....*....|....
gi 446892528 239 GRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK08252 231 FTSADAKEGATAFAEKRAPVWTGK 254
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
1-259 2.87e-37

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 131.93  E-value: 2.87e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDL 80
Cdd:PRK07509   1 MMDRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVKSVASSPGNAVKLL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 -----GMSVERFYNPLVRRlaKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVA 155
Cdd:PRK07509  81 fkrlpGNANLAQRVSLGWR--RLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLV 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 156 GRARAMGLALLGNQLSAEQAHEWGMIWQVVDDeTLADtAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQ 235
Cdd:PRK07509 159 RKDVARELTYTARVFSAEEALELGLVTHVSDD-PLAA-ALALAREIAQRSPDAIAAAKRLINRSWTASVRALLARESVEQ 236
                        250       260
                 ....*....|....*....|....*
gi 446892528 236 -RLAGrSADYREGVSAFLAKRSPQF 259
Cdd:PRK07509 237 iRLLL-GKNQKIAVKAQMKKRAPKF 260
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
2-262 7.48e-37

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 131.02  E-value: 7.48e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEF--ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQD---LNDRNVDPTG 75
Cdd:PRK05809   1 MELknVILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGeKAFVAGADiseMKDLNEEEGR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  76 PAPDLGmsverfyNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVA 155
Cdd:PRK05809  81 KFGLLG-------NKVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIV 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 156 GRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQ 235
Cdd:PRK05809 154 GPGKAKELIYTGDMINAEEALRIGLVNKVVEPEKLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDF 233
                        250       260
                 ....*....|....*....|....*..
gi 446892528 236 RLAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK05809 234 GECFSTEDQTEGMTAFVEKREKNFKNK 260
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
13-262 3.34e-36

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 128.93  E-value: 3.34e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  13 VMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRnvdptgpAPDLGMSVERF----Y 88
Cdd:PRK06563   9 VLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADV-------APKLAAGGFPFpeggI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  89 NPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGN 168
Cdd:PRK06563  82 DPWGTVGRRLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGD 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 169 QLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFG----LGLIKQAINSAETNTLdTQLDLERdyQRLAGrSADY 244
Cdd:PRK06563 162 EFDAQEALRLGLVQEVVPPGEQLERAIELAERIARAAPLGvqatLASARAAVREGEAAAA-AQLPPEL--RPLFT-SEDA 237
                        250
                 ....*....|....*...
gi 446892528 245 REGVSAFLAKRSPQFTGK 262
Cdd:PRK06563 238 KEGVQAFLERRPARFKGR 255
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
3-260 7.52e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 128.24  E-value: 7.52e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   3 EFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLndrnvdptGPAPDLGM 82
Cdd:PRK05862   4 ETILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADI--------KEMADLSF 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  83 sVERFYNPLV---RRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRAR 159
Cdd:PRK05862  76 -MDVYKGDYItnwEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAK 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 160 AMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAG 239
Cdd:PRK05862 155 AMDLCLTGRMMDAAEAERAGLVSRVVPADKLLDEALAAATTIASFSLPAVMMAKEAVNRAYETTLAEGLLFERRLFHSLF 234
                        250       260
                 ....*....|....*....|.
gi 446892528 240 RSADYREGVSAFLAKRSPQFT 260
Cdd:PRK05862 235 ATEDQKEGMAAFVEKRKPVFK 255
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
1-262 1.83e-34

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 124.81  E-value: 1.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPeRLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLNDRNvdpTGPAPD 79
Cdd:PRK03580   1 MSESLHTTRNGSILEITLDRP-KANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGeKFFSAGWDLKAAA---EGEAPD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  80 LGMSVERFYNplVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRAR 159
Cdd:PRK03580  77 ADFGPGGFAG--LTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAI 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 160 AMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETntldtqLDLERDYQRLAG 239
Cdd:PRK03580 155 ANEMVMTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKEIYRETSE------MPVEEAYRYIRS 228
                        250       260       270
                 ....*....|....*....|....*....|...
gi 446892528 240 R----------SADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK03580 229 GvlkhypsvlhSEDALEGPRAFAEKRDPVWKGR 261
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
9-262 6.81e-34

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 123.29  E-value: 6.81e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   9 VEK--GVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMsver 86
Cdd:PRK07799   9 VEQrgHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKKPPGDSFKDGS---- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  87 FYNPLVRRLAK---LPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGL 163
Cdd:PRK07799  85 YDPSRIDALLKgrrLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDL 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 164 ALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSAD 243
Cdd:PRK07799 165 LLTGRHITAAEAKEIGLIGHVVPDGQALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSED 244
                        250
                 ....*....|....*....
gi 446892528 244 YREGVSAFLAKRSPQFTGK 262
Cdd:PRK07799 245 AKEGPRAFAEKRAPNFQGR 263
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
6-261 2.62e-33

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 121.67  E-value: 2.62e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   6 LSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNdrNVDPTGPAPDLGMSVE 85
Cdd:PRK07327  15 FDRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKAFSAGGDLA--LVEEMADDFEVRARVW 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  86 RFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLAL 165
Cdd:PRK07327  93 REARDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLL 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 166 LGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINS---AETNTLDTQLDLErdYQRLAGrsA 242
Cdd:PRK07327 173 LCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAGSQTAIRWTKYALNNwlrMAGPTFDTSLALE--FMGFSG--P 248
                        250
                 ....*....|....*....
gi 446892528 243 DYREGVSAFLAKRSPQFTG 261
Cdd:PRK07327 249 DVREGLASLREKRAPDFPG 267
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
1-262 3.47e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 118.87  E-value: 3.47e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLN-----------DR 69
Cdd:PRK05995   2 MYETLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKAFCAGADLNwmkkmagysddEN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  70 NVDPtgpapdlgmsveRFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTW 149
Cdd:PRK05995  82 RADA------------RRLADMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPY 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 150 LLpRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETL-ADTAQQLARHLATQPTF---GLGLIkQAINSAEtntLD 225
Cdd:PRK05995 150 VI-RAMGERAARRYFLTAERFDAAEALRLGLVHEVVPAEALdAKVDELLAALVANSPQAvraGKRLV-RDVAGRP---ID 224
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 446892528 226 TQLdLERDYQRLA--GRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK05995 225 AAL-IADTASRIAliRATEEAREGVAAFLEKRKPAWRGR 262
PLN02888 PLN02888
enoyl-CoA hydratase
5-256 3.75e-32

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 118.70  E-value: 3.75e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDrnvdptgpAPDL--GM 82
Cdd:PLN02888  12 LVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLTA--------AEEVfkGD 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  83 SVERFYNPLVRrLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMG 162
Cdd:PLN02888  84 VKDVETDPVAQ-MERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRARE 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 163 LALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAetntldTQLDLERDYQRLAGRSA 242
Cdd:PLN02888 163 VSLTAMPLTAETAERWGLVNHVVEESELLKKAREVAEAIIKNNQGMVLRYKSVINDG------LKLDLGHALQLEKERAH 236
                        250       260
                 ....*....|....*....|..
gi 446892528 243 DYREGVSA--------FLAKRS 256
Cdd:PLN02888 237 DYYNGMTKeqfqkmqeFIAGRS 258
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
1-262 1.56e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 117.02  E-value: 1.56e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLND-RNVDptgpAP 78
Cdd:PRK06144   6 STDELLLEVRGGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGdKAFVAGTDIAQfRAFS----TA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  79 DLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSK-LGlipDCGGTWLLPRVA-- 155
Cdd:PRK06144  82 EDAVAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPIARtLG---NCLSMSNLARLVal 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 156 -GRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINsaetNTLDTQLDLERDY 234
Cdd:PRK06144 159 lGAARVKDMLFTARLLEAEEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKEALR----RLRREGLPDGDDL 234
                        250       260
                 ....*....|....*....|....*...
gi 446892528 235 QRLAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK06144 235 IRMCYMSEDFREGVEAFLEKRPPKWKGR 262
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
1-250 5.52e-31

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 115.46  E-value: 5.52e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDL 80
Cdd:PRK06190   2 TEPILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADPAFCAGLDLKELGGDGSAYGAQD 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSverfynPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA 160
Cdd:PRK06190  82 ALP------NPSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGR 240
Cdd:PRK06190 156 RRMSLTGDFLDAADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAEAARAHNR 235
                        250
                 ....*....|....*.
gi 446892528 241 S------ADYREGVSA 250
Cdd:PRK06190 236 SvspdgiAARREAVMA 251
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
10-262 5.87e-31

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 115.54  E-value: 5.87e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  10 EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLN--DRNVDPTGP-----APDLGM 82
Cdd:PRK07468  12 ARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGwmRAQMTADRAtrieeARRLAM 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  83 sverfynpLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVaGRARAMG 162
Cdd:PRK07468  92 --------MLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARM-GEANARR 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 163 LALLGNQLSAEQAHEWGMIWQVVDDETL-ADTAQQLARHLATQPtfglglikQAINSA-----ETNTLDTQLDLERDYQR 236
Cdd:PRK07468 163 VFMSARLFDAEEAVRLGLLSRVVPAERLdAAVEAEVTPYLSCAP--------GAVAAAkalvrALGAPIDEAVIDATIEA 234
                        250       260
                 ....*....|....*....|....*...
gi 446892528 237 LAGR--SADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK07468 235 LADTweTEEAREGIAAFFDKRAPAWRGG 262
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
1-261 1.86e-30

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 114.27  E-value: 1.86e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPtGPApdl 80
Cdd:PRK08139   9 EAPLLLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGKAFCAGHDLKEMRAAR-GLA--- 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 gmsverFYNPLVRR-------LAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLI---PDCGgtwl 150
Cdd:PRK08139  85 ------YFRALFARcsrvmqaIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA---- 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 151 LPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSaetntlDTQLDL 230
Cdd:PRK08139 155 LSRNVPRKQAMEMLLTGEFIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEAFYR------QAEMPL 228
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 446892528 231 ERDYQrLAGR-------SADYREGVSAFLAKRSPQFTG 261
Cdd:PRK08139 229 ADAYA-YAGDvmaenmmAEDAEEGIDAFLEKRPPEWRG 265
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
1-254 1.49e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 111.42  E-value: 1.49e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILshVEK-----GVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTG 75
Cdd:PRK06023   1 MTDHIL--VERpgahpGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQDFLAAAMG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  76 pAPDLGMSVERFynplVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVA 155
Cdd:PRK06023  79 -GTSFGSEILDF----LIALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLM 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 156 GRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDtQLDLERDYQ 235
Cdd:PRK06023 154 GHQRAFALLALGEGFSAEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKPPQALQIARDLMRGPREDILA-RIDEEAKHF 232
                        250
                 ....*....|....*....
gi 446892528 236 RLAGRSADYREGVSAFLAK 254
Cdd:PRK06023 233 AARLKSAEARAAFEAFMRR 251
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
2-260 1.64e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 109.54  E-value: 1.64e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFIL-SHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPA--- 77
Cdd:PRK05864   8 MSLVLvDHPRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRGFSSGADHKSAGVVPHVEGltr 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  78 PDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLI-PDCGGTWLLPRVAG 156
Cdd:PRK05864  88 PTYALRSMELLDDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLSYLLPRAIG 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 157 RARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSA-ETNTLDTQLDLE---R 232
Cdd:PRK05864 168 SSRAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGlDAASLEAHMQAEglgQ 247
                        250       260
                 ....*....|....*....|....*...
gi 446892528 233 DYQRLAgrSADYREGVSAFLAKRSPQFT 260
Cdd:PRK05864 248 LFVRLL--TANFEEAVAARAEKRPPVFT 273
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
3-220 1.74e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 109.67  E-value: 1.74e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   3 EFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND----RNVDP----- 73
Cdd:PRK08290   4 EYVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLGSgtpgRDRDPgpdqh 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  74 --------TGPAPDLGMSVE-RFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLipd 144
Cdd:PRK08290  84 ptlwwdgaTKPGVEQRYAREwEVYLGMCRRWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI--- 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446892528 145 CGGTWLL-PRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAE 220
Cdd:PRK08290 161 PGVEYFAhPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAVNQTL 237
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
5-262 4.84e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 107.87  E-value: 4.84e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLNDRNVDPTGPApdlgmS 83
Cdd:PRK06127  13 LLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGeKAFVSGADISQFEESRSDAE-----A 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  84 VERfYNPLVRR----LAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRAR 159
Cdd:PRK06127  88 VAA-YEQAVEAaqaaLADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSA 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 160 AMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAInsAETNTLDTQLDLERDYQRLAG 239
Cdd:PRK06127 167 AKDLFYTARRFDAAEALRIGLVHRVTAADDLETALADYAATIAGNAPLTLRAAKRAI--AELLKDEPERDMAACQALVAA 244
                        250       260
                 ....*....|....*....|....*
gi 446892528 240 --RSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK06127 245 cfDSEDYREGRAAFMEKRKPVFKGR 269
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
2-262 8.46e-28

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 107.03  E-value: 8.46e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDtIRCLLLtGAGRG---FCAGQDLNDRnvdPTGPAP 78
Cdd:PRK11423   3 MQYVNVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVIL-RAPSGskvWSAGHDIHEL---PSGGRD 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  79 DLGMSverfyNPL---VRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVA 155
Cdd:PRK11423  78 PLSYD-----DPLrqiLRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDA 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 156 GRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAI---NSAETNTLDTqldLER 232
Cdd:PRK11423 153 GFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEQLrvlGEAHPMNPDE---FER 229
                        250       260       270
                 ....*....|....*....|....*....|..
gi 446892528 233 --DYQRLAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK11423 230 iqGLRRAVYDSEDYQEGMNAFLEKRKPVFVGH 261
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
1-262 3.42e-27

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 105.55  E-value: 3.42e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPErLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNvDPTGPAPDL 80
Cdd:PRK06495   2 MMSQLKLEVSDHVAVVTLDNPP-VNALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKGRP-DVIKGPGDL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 ----GMSVERFYNplVRRLAKlpkPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIpdcGGTWLLPRVAG 156
Cdd:PRK06495  80 rahnRRTRECFHA--IRECAK---PVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFG 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 157 RARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQR 236
Cdd:PRK06495 152 HSLTRRMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITA 231
                        250       260
                 ....*....|....*....|....*.
gi 446892528 237 LAGRSADYREGVSAFLAKRSPQFTGK 262
Cdd:PRK06495 232 KLAKTEDAKEAQRAFLEKRPPVFKGR 257
PLN02600 PLN02600
enoyl-CoA hydratase
12-262 1.28e-25

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 101.03  E-value: 1.28e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  12 GVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRG-FCAGQDLNDRNVdpTGPApdlgmSVERFYNP 90
Cdd:PLN02600   4 GIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGvFCAGADLKERRK--MSPS-----EVQKFVNS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  91 L---VRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLG 167
Cdd:PLN02600  77 LrstFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTG 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 168 NQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERD-YQRLAgRSADYRE 246
Cdd:PLN02600 157 RRIGAREAASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEEcYEQVL-KTKDRLE 235
                        250
                 ....*....|....*.
gi 446892528 247 GVSAFLAKRSPQFTGK 262
Cdd:PLN02600 236 GLAAFAEKRKPVYTGK 251
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
1-257 4.45e-25

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 99.76  E-value: 4.45e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPApDL 80
Cdd:PRK07827   4 VDTLVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAGGGGGDPY-DA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRArA 160
Cdd:PRK07827  83 AVARAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRA-A 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDD--ETLADTAQQLARHlATQptfGLglikqainsAETNTLDTQLDLE---RDYQ 235
Cdd:PRK07827 162 ARYYLTGEKFGAAEAARIGLVTAAADDvdAAVAALLADLRRG-SPQ---GL---------AESKALTTAAVLAgfdRDAE 228
                        250       260
                 ....*....|....*....|....*...
gi 446892528 236 RLAGRSA------DYREGVSAFLAKRSP 257
Cdd:PRK07827 229 ELTEESArlfvsdEAREGMTAFLQKRPP 256
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
9-261 2.52e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 98.12  E-value: 2.52e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   9 VEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND-RNVDPTGPAPDLGMSVERF 87
Cdd:PRK06142  12 LADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAmAGVFGQLGKDGLARPRTDL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  88 YNpLVRRL-------AKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA 160
Cdd:PRK06142  92 RR-EILRLqaainavADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGHL 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 161 MGLALLGNQLSAEQAHEWGMIWQVVDD-ETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAG 239
Cdd:PRK06142 171 RELALTGRDIDAAEAEKIGLVNRVYDDaDALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAAML 250
                        250       260
                 ....*....|....*....|..
gi 446892528 240 RSADYREGVSAFLAKRSPQFTG 261
Cdd:PRK06142 251 PSKDLTEAIAAHMEKRPPEFTG 272
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
15-237 1.32e-23

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 97.16  E-value: 1.32e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   15 TLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQD---LNDRNVDPTGPApdlgmsVERF--- 87
Cdd:pfam16113   3 VITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGeRAFCAGGDvraLYEAAKAGGGEA------GRDFfre 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   88 -YNpLVRRLAKLPKPVICAVngvaagagatlalggD-IV--------------IAARSAKFVMAFSKLGLIPDCGGTWLL 151
Cdd:pfam16113  77 eYR-LNYLIATYPKPYVALM---------------DgIVmgggvglsvhgsfrVVTERTRFAMPETAIGLFPDVGGSYFL 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  152 PRVAGRArAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADtaqqLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLE 231
Cdd:pfam16113 141 SRLPGEL-GLYLALTGARLNGADALAAGLATHYVPSARLPA----LEEALAALDWSDPADVDAVLAEFAEESDPPPSPLA 215

                  ....*.
gi 446892528  232 RDYQRL 237
Cdd:pfam16113 216 AHREAI 221
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
13-262 2.06e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 95.09  E-value: 2.06e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  13 VMTLTLNRPERLNSFNDEMHAQLAECLKQVErDDTIRCLLLTGAGRGFCAGQDLndrnvDPTGPAPDLGMSVERfynpLV 92
Cdd:PRK07854  10 VLTIELQRPERRNALNAELCEELREAVRKAV-DESARAIVLTGQGTVFCAGADL-----SGDVYADDFPDALIE----ML 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  93 RRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDcggTWLLPRVA-----GRARAMGLAllG 167
Cdd:PRK07854  80 HAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRLSslvggGRARAMLLG--A 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 168 NQLSAEQAHEWGMIwQVVDDetlADTAQQLARHLATQPTFGLGLIKQAINSAetNTLDTQLDLERDYQRLAGRSADYREG 247
Cdd:PRK07854 155 EKLTAEQALATGMA-NRIGT---LADAQAWAAEIAGLAPLALQHAKRVLNDD--GAIEEAWPAHKELFDKAWASQDAIEA 228
                        250
                 ....*....|....*
gi 446892528 248 VSAFLAKRSPQFTGK 262
Cdd:PRK07854 229 QVARIEKRPPKFQGA 243
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
2-219 4.56e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 92.80  E-value: 4.56e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND---RNVDPTGPAP 78
Cdd:PRK08272   9 LKTMTYEVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLSAyaeGSSSGGGGGA 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  79 DLGMSVERFYNP------------------LVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAkfvmafsKLG 140
Cdd:PRK08272  89 YPGKRQAVNHLPddpwdpmidyqmmsrfvrGFMSLWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDA-------KIG 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 141 LIPdcGGTWLLPRVA------GRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQ 214
Cdd:PRK08272 162 YPP--TRVWGVPATGmwayrlGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAVPVNQLAMVKL 239

                 ....*
gi 446892528 215 AINSA 219
Cdd:PRK08272 240 AVNSA 244
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
1-205 9.75e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 90.73  E-value: 9.75e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLN-----DRN-VDPT 74
Cdd:PRK08259   1 MSMSVRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKavgtgRGNrLHPS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  75 GPAPdlgMSVERFynplvrrlaKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLG--LIPdcGGTWLLP 152
Cdd:PRK08259  81 GDGP---MGPSRM---------RLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGvpLID--GGTVRLP 146
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446892528 153 RVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQP 205
Cdd:PRK08259 147 RLIGHSRAMDLILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAAFP 199
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
5-259 1.46e-21

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 90.72  E-value: 1.46e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLNDRN----VDPTGpapd 79
Cdd:PRK07396  15 ILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGdKAFCSGGDQKVRGyggyVDDDG---- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  80 lgmsVERFyNPL-VRRLAK-LPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIpDCG-GTWLLPRVAG 156
Cdd:PRK07396  91 ----VPRL-NVLdLQRLIRtCPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSF-DGGyGASYLARIVG 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 157 RARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINsAETntlDTQLDLerdyQR 236
Cdd:PRK07396 165 QKKAREIWFLCRQYDAQEALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALN-ADC---DGQAGL----QE 236
                        250       260       270
                 ....*....|....*....|....*....|
gi 446892528 237 LAG-------RSADYREGVSAFLAKRSPQF 259
Cdd:PRK07396 237 LAGnatmlfyMTEEAQEGRNAFNEKRQPDF 266
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
1-258 1.74e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 90.36  E-value: 1.74e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERlNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLN-----DRNVDPT 74
Cdd:PRK09076   1 MMIELDLEIDGHVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGeKFFSAGADLNlfadgDKAVARE 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  75 GpAPDLGMSVERFYNPLVRRLAK---------LPKPVICavngvaagagatlalggDIVIAARSAKFVMAFSKLGLIPDC 145
Cdd:PRK09076  80 M-ARRFGEAFEALSAFRGVSIAAingyamgggLECALAC-----------------DIRIAEEQAQMALPEASVGLLPCA 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 146 GGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLD 225
Cdd:PRK09076 142 GGTQNLPWLVGEGWAKRMILCGERVDAATALRIGLVEEVVEKGEAREAALALAQKVANQSPSAVAACKTLIQAARNGPRA 221
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 446892528 226 TQLDLERdyQRLAG--RSADYREGVSAFLAKRSPQ 258
Cdd:PRK09076 222 AALALER--ELFVDlfDTEDQREGVNAFLEKRAPQ 254
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
8-260 1.78e-21

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 91.24  E-value: 1.78e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   8 HVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTG-------AGRGFCAGQDLNDRNVD-------P 73
Cdd:PRK08321  30 AVDQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTGngpspkdGGWAFCSGGDQRIRGRDgyqyaegD 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  74 TGPAPDLGMSvERFYNPLVRRLAK-LPKPVICAVNGVAAGAGATLALGGDIVIAARS-AKF------VMAFsklglipDC 145
Cdd:PRK08321 110 EADTVDPARA-GRLHILEVQRLIRfMPKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFkqtdadVGSF-------DG 181
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 146 G-GTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTL 224
Cdd:PRK08321 182 GyGSAYLARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAREINGKSPTAMRMLKYAFNLTDDGLV 261
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 446892528 225 DTQLdLERDYQRLAGRSADYREGVSAFLAKRSPQFT 260
Cdd:PRK08321 262 GQQL-FAGEATRLAYMTDEAQEGRDAFLEKRDPDWS 296
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
1-257 4.61e-21

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 90.65  E-value: 4.61e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLndRNVDPTGPAPD 79
Cdd:PRK05617   1 TEDEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGeRGFCAGGDI--RALYEAARAGD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  80 lGMSVERFYN---PLVRRLAKLPKPVIcavngvaagagatlaLGGD-IV--------------IAARSAKFVMAFSKLGL 141
Cdd:PRK05617  79 -PLAADRFFReeyRLNALIARYPKPYI---------------ALMDgIVmgggvgisahgshrIVTERTKMAMPETGIGF 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 142 IPDCGGTWLLPRVAGRArAMGLALLGNQLSAEQA------------HEWGMIWQVVDDETLADTAQQ----LARHLATQP 205
Cdd:PRK05617 143 FPDVGGTYFLSRAPGAL-GTYLALTGARISAADAlyagladhfvpsADLPALLDALISLRWDSGADVvdaaLAAFATPAP 221
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446892528 206 TFGLGLIKQAINsaETNTLDTqldLERDYQRLAGRSADYREGVSAFLAKRSP 257
Cdd:PRK05617 222 ASELAAQRAWID--ECFAGDT---VEDIIAALEADGGEFAAKTADTLRSRSP 268
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
2-260 5.83e-20

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 86.49  E-value: 5.83e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRN-VDPTGPAPDL 80
Cdd:PLN02664   7 LEIIQKSPNSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNsISEQSSSGDR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSVER------FYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRV 154
Cdd:PLN02664  87 GRSGERlrrkikFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSI 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 155 AGRARAMGLALLGNQLSAEQAHEWGMIWQVV-DDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERD 233
Cdd:PLN02664 167 VGYGNAMELALTGRRFSGSEAKELGLVSRVFgSKEDLDEGVRLIAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVAT 246
                        250       260
                 ....*....|....*....|....*..
gi 446892528 234 YQRLAGRSADYREGVSAFLAKRSPQFT 260
Cdd:PLN02664 247 WNSAMLVSDDLNEAVSAQIQKRKPVFA 273
PLN02921 PLN02921
naphthoate synthase
9-260 1.67e-19

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 85.99  E-value: 1.67e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   9 VEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLNDRN----VDPTGPAP----D 79
Cdd:PLN02921  73 VGEGIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGtKAFCSGGDQAVRGkdgyVGPDDAGRlnvlD 152
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  80 LGMSVERfynplvrrlakLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIpDCG-GTWLLPRVAGRA 158
Cdd:PLN02921 153 LQIQIRR-----------LPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARLVGQK 220
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 159 RAMGLALLGNQLSAEQAHEWGMIWQVVDDETL-ADTAQQLARHLATQPTfGLGLIKQAINSAETNTLDTQlDLERDYQRL 237
Cdd:PLN02921 221 KAREMWFLARFYTASEALKMGLVNTVVPLDELeGETVKWCREILRNSPT-AIRVLKSALNAADDGHAGLQ-ELGGNATLL 298
                        250       260
                 ....*....|....*....|...
gi 446892528 238 AGRSADYREGVSAFLAKRSPQFT 260
Cdd:PLN02921 299 FYGSEEGNEGRTAYLEGRAPDFS 321
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
8-256 2.54e-19

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 84.68  E-value: 2.54e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   8 HVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND--RNVDPTGPApdLGMSVE 85
Cdd:PRK09120  13 EVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLKEyfRETDAQPEI--LQERIR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  86 RFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLAL 165
Cdd:PRK09120  91 REAYGWWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIM 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 166 LGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTldtqLDLERDYQRLAGRSADYR 245
Cdd:PRK09120 171 TGETFTGRKAAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGFKRVRELT----WDQAEDYLYAKLEQANSL 246
                        250
                 ....*....|....*...
gi 446892528 246 -------EGVSAFLAKRS 256
Cdd:PRK09120 247 dpeggreEGLKQFLDDKS 264
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
1-259 1.41e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 80.38  E-value: 1.41e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEF--ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLN------DRNVD 72
Cdd:PRK12478   1 TPDFqtLLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAGRAFSGGYDFGggfqhwGEAMM 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  73 PTG---PAPDLGMSVERFYNPLVRRLA--KLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKL-GLIpdCG 146
Cdd:PRK12478  81 TDGrwdPGKDFAMVTARETGPTQKFMAiwRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAY--LT 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 147 GTWLLpRVaGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETL----ADTAQQLARHLATQPTFGLGLIKQAINS---A 219
Cdd:PRK12478 159 GMWLY-RL-SLAKVKWHSLTGRPLTGVQAAEAELINEAVPFERLearvAEVATELARIPLSQLQAQKLIVNQAYENmglA 236
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446892528 220 ETNTLDTQLD-LERDYQRLAG--RSADyREGVSAFLAKRSPQF 259
Cdd:PRK12478 237 STQTLGGILDgLMRNTPDALEfiRTAE-TQGVRAAVERRDGPF 278
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
11-257 5.11e-17

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 78.31  E-value: 5.11e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  11 KGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDL----NDRNVDPTGPAPDLGMSVER 86
Cdd:PRK05674  14 RGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLawmqQSADLDYNTNLDDARELAEL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  87 FYNplvrrLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRArAMGLALL 166
Cdd:PRK05674  94 MYN-----LYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERA-ARRYALT 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 167 GNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTqlDLERDYQRLAGR---SAD 243
Cdd:PRK05674 168 AERFDGRRARELGLLAESYPAAELEAQVEAWIANLLLNSPQALRASKDLLREVGDGELSP--ALRRYCENAIARirvSAE 245
                        250
                 ....*....|....
gi 446892528 244 YREGVSAFLAKRSP 257
Cdd:PRK05674 246 GQEGLRAFLEKRTP 259
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
10-202 1.53e-16

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 76.65  E-value: 1.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  10 EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIrcLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGmSVERFYN 89
Cdd:PRK07112  11 QGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATI--VVLEGLPEVFCFGADFSAIAEKPDAGRADLI-DAEPLYD 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  90 pLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVaGRARAMGLALLGNQ 169
Cdd:PRK07112  88 -LWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPACVLPFLIRRI-GTQKAHYMTLMTQP 165
                        170       180       190
                 ....*....|....*....|....*....|...
gi 446892528 170 LSAEQAHEWGMIwqvvdDETLADTAQQLARHLA 202
Cdd:PRK07112 166 VTAQQAFSWGLV-----DAYGANSDTLLRKHLL 193
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
10-203 2.08e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 76.21  E-value: 2.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  10 EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVErdDTIRCLLLTGAGRGFCAGQDLND-RNVDPTGpapdlGMSVERFY 88
Cdd:PRK08150   9 DGGVATIGLNRPAKRNALNDGLIAALRAAFARLP--EGVRAVVLHGEGDHFCAGLDLSElRERDAGE-----GMHHSRRW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  89 NPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGN 168
Cdd:PRK08150  82 HRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGR 161
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 446892528 169 QLSAEQAHEWGMIWQVVDDETLADTAQQLARHLAT 203
Cdd:PRK08150 162 VYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQ 196
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
1-213 5.11e-15

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 72.31  E-value: 5.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGqdlndrnvdptGPAPDL 80
Cdd:PRK07110   3 MKVVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATG-----------GTQEGL 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 gMSVERFY-----NPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVA 155
Cdd:PRK07110  72 -LSLQTGKgtfteANLYSLALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKL 150
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446892528 156 GRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIK 213
Cdd:PRK07110 151 GLALGQEMLLTARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLAEKPRHSLVLLK 208
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
2-257 9.74e-15

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 71.54  E-value: 9.74e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPErLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPdlg 81
Cdd:PRK07938   1 MPITSTTPEPGIAEVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGFTAL--- 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  82 MSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFvmafsklGLiPDC-----GGTWLLPRVAG 156
Cdd:PRK07938  77 IDANRGCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATF-------GL-PEVdrgalGAATHLQRLVP 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528 157 RARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINSAETntldtqLDLERDYQ- 235
Cdd:PRK07938 149 QHLMRALFFTAATITAAELHHFGSVEEVVPRDQLDEAALEVARKIAAKDTRVIRAAKEALNGIDP------QDVERSYRw 222
                        250       260       270
                 ....*....|....*....|....*....|
gi 446892528 236 --------RLAGRSADYREgvsAFLAKRSP 257
Cdd:PRK07938 223 eqgftfelNLAGVSDEHRD---AFVEKRKA 249
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
2-202 1.89e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 70.83  E-value: 1.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHV-----EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLNDR-NVDPt 74
Cdd:PRK06143   1 MIMLNAHAgvtrdDRGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGeKAFIGGADIKEMaTLDQ- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  75 gpapdlgMSVERFynplVRRLAKL-------PKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGlIPDCGG 147
Cdd:PRK06143  80 -------ASAEAF----ISRLRDLcdavrhfPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIH 147
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446892528 148 TWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLA 202
Cdd:PRK06143 148 AALLPRLIGWARTRWLLLTGETIDAAQALAWGLVDRVVPLAELDAAVERLAASLA 202
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
1-217 3.58e-13

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 66.79  E-value: 3.58e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHV-----EKGVMTLTLNRPERlNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLND-RNVDPt 74
Cdd:PRK05869   1 MNEFVNVVVsdgsqDAGLATLLLSRPPT-NALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPElRTLSA- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  75 gpapDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRV 154
Cdd:PRK05869  79 ----QEADTAARVRQQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRA 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446892528 155 AGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAIN 217
Cdd:PRK05869 155 AGPSRAKELVFSGRFFDAEEALALGLIDEMVAPDDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
2-229 1.40e-12

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 66.75  E-value: 1.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   2 MEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDL----NDRNVDPTGPA 77
Cdd:PLN02874  10 EEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDLkmfyDGRESDDSCLE 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  78 pdlgmSVERFYnPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGR 157
Cdd:PLN02874  90 -----VVYRMY-WLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGH 163
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446892528 158 araMG--LALLGNQLSAEQAHEWGMIWQVVDDETLADtaqqLARHLATQPTFGLGLIKQAInsaETNTLDTQLD 229
Cdd:PLN02874 164 ---LGeyLALTGARLNGKEMVACGLATHFVPSEKLPE----LEKRLLNLNSGDESAVQEAI---EEFSKDVQAD 227
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
9-224 2.22e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 66.40  E-value: 2.22e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528    9 VEKGVMTLTLNRPE-RLNSFNDEMHAQLAECLKQVERDDTIR-CLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLgmsVER 86
Cdd:TIGR02441  19 VKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKsAVLISGKPGSFVAGADIQMIAACKTAQEVTQ---LSQ 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   87 FYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSK--LGLIPDCGGTWLLPRVAGRARAMGLA 164
Cdd:TIGR02441  96 EGQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEvmLGLLPGAGGTQRLPKLTGVPAALDMM 175
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446892528  165 LLGNQLSAEQAHEWGMIWQVVDD-------------ETLADTAQQLARHLAT---QPTFGLGLIKQAINSAETNTL 224
Cdd:TIGR02441 176 LTGKKIRADRAKKMGIVDQLVDPlgpglkpaeentiEYLEEVAVKFAQGLANgklSINRDKGLVHKITQYVMTNPF 251
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
5-208 3.55e-11

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 62.43  E-value: 3.55e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   5 ILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSV 84
Cdd:PLN02988  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVRDIEQGNWRLGANF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  85 ERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMgLA 164
Cdd:PLN02988  91 FSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEY-VG 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 446892528 165 LLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFG 208
Cdd:PLN02988 170 LTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFA 213
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
10-217 1.85e-09

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 57.56  E-value: 1.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  10 EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLgMSVERFYN 89
Cdd:PRK11730  14 EDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKDAFIVGADITEFLSLFAAPEEEL-SQWLHFAN 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  90 PLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQ 169
Cdd:PRK11730  93 SIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKD 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446892528 170 LSAEQAHEWGMIWQVVDDETLADTAqqlarhlatqptfgLGLIKQAIN 217
Cdd:PRK11730 173 VRAEDALKVGAVDAVVAPEKLQEAA--------------LALLKQAIA 206
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
4-199 1.93e-09

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 57.60  E-value: 1.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   4 FILSHVEKGVMTLTLNRP-ERLNSFNDEMHAQLAECLKQVERDDTIRCLLLT-GAGRGFCAGQDLNDRNVDPTGP-APDL 80
Cdd:PRK11154   7 FTLNVREDNIAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKELKGVVFIsGKPDNFIAGADINMLAACKTAQeAEAL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSVERFYNplvrRLAKLPKPVI-----------------CavngvaagagatlalggDIVIAARSAKFVMAFS--KLGL 141
Cdd:PRK11154  87 ARQGQQLFA----EIEALPIPVVaaihgaclggglelalaC-----------------HYRVCTDDPKTVLGLPevQLGL 145
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446892528 142 IPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLAR 199
Cdd:PRK11154 146 LPGSGGTQRLPRLIGVSTALDMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAK 203
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
15-206 2.43e-09

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 57.00  E-value: 2.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  15 TLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDlgmSVERFYNPL--- 91
Cdd:PLN02157  49 TAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGGDIVSLYHLRKRGSPD---AIREFFSSLysf 125
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  92 VRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMgLALLGNQLS 171
Cdd:PLN02157 126 IYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEY-LGLTGLKLS 204
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 446892528 172 AEQAHEWGMIWQVVDDETLADTAQQLARHLATQPT 206
Cdd:PLN02157 205 GAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPS 239
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
1-203 3.22e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 49.97  E-value: 3.22e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528   1 MMEFILSHVEKGVMTLTLNRpERLNSFNDEMHAQLAECLKQVERDDTIrcLLLTGAGRGFCAGQDLNdrnVDPTGPAPDL 80
Cdd:PRK06213   1 MSELVSYTLEDGVATITLDD-GKVNALSPAMIDALNAALDQAEDDRAV--VVITGQPGIFSGGFDLK---VMTSGAQAAI 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  81 GMSVERFynPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARsakfvmAFSKLGL--------IPDCG---GTW 149
Cdd:PRK06213  75 ALLTAGS--TLARRLLSHPKPVIVACTGHAIAKGAFLLLSADYRIGVH------GPFKIGLnevaigmtMPHAAielARD 146
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446892528 150 LLPRVAGRaRAMGLALLgnqLSAEQAHEWGMIWQVVDDETLADTAQQLARHLAT 203
Cdd:PRK06213 147 RLTPSAFQ-RAVINAEM---FDPEEAVAAGFLDEVVPPEQLLARAQAAARELAG 196
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
11-205 1.16e-06

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 48.72  E-value: 1.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  11 KGVMTLTLNRpERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRG--FCAGQDLNDRNVDPTGPApdlgmSVERFY 88
Cdd:PLN03214  20 GGIAVVWLAK-EPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGLRRdvFTAGNDIAELYAPKTSAA-----RYAEFW 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  89 ---NPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGL-IPDCGGTWLLPRVAGRARAMGLA 164
Cdd:PLN03214  94 ltqTTFLVRLLRSRLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLL 173
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 446892528 165 LLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQP 205
Cdd:PLN03214 174 LRGRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALKLP 214
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
18-206 2.88e-05

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 44.58  E-value: 2.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  18 LNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQD-------LNDRNVDPTgpapdlgmsvERFYNP 90
Cdd:PLN02851  57 LNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSGRAFCSGADvvslyhlINEGNVEEC----------KLFFEN 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446892528  91 L---VRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRaraMG--LAL 165
Cdd:PLN02851 127 LykfVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLPGY---LGeyLAL 203
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 446892528 166 LGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPT 206
Cdd:PLN02851 204 TGQKLNGVEMIACGLATHYCLNARLPLIEERLGKLLTDDPA 244
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
122-187 5.16e-04

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 40.67  E-value: 5.16e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446892528 122 DIVIAARSAKF---VMAFsklGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDD 187
Cdd:PRK08788 144 HTIIAERGAKMgfpEILF---NLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELHDMGLVDVLVED 209
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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