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Conserved domains on  [gi|446900496|ref|WP_000977752|]
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MULTISPECIES: lipoprotein antitoxin entericidin A [Escherichia]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10081 super family cl22944
lipoprotein toxin entericidin B;
1-41 2.67e-09

lipoprotein toxin entericidin B;


The actual alignment was detected with superfamily member PRK09810:

Pssm-ID: 451461  Cd Length: 41  Bit Score: 46.16  E-value: 2.67e-09
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 446900496  1 MMKRLILLALLASTLLTGCNTARGFGEDIKHLGNSISRAAS 41
Cdd:PRK09810  1 MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS 41
 
Name Accession Description Interval E-value
PRK09810 PRK09810
lipoprotein antitoxin entericidin A;
1-41 2.67e-09

lipoprotein antitoxin entericidin A;


Pssm-ID: 137533  Cd Length: 41  Bit Score: 46.16  E-value: 2.67e-09
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 446900496  1 MMKRLILLALLASTLLTGCNTARGFGEDIKHLGNSISRAAS 41
Cdd:PRK09810  1 MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS 41
COG5510 COG5510
Predicted small secreted protein [Function unknown];
18-41 5.05e-07

Predicted small secreted protein [Function unknown];


Pssm-ID: 444261  Cd Length: 45  Bit Score: 40.22  E-value: 5.05e-07
                        10        20
                ....*....|....*....|....
gi 446900496 18 GCNTARGFGEDIKHLGNSISRAAS 41
Cdd:COG5510  19 GCNTVKGAGEDIESGGEAIEDAAE 42
Entericidin pfam08085
Entericidin EcnA/B family; This family consists of the entericidin antidote/toxin peptides. ...
 21-40 1.59e-03

Entericidin EcnA/B family; This family consists of the entericidin antidote/toxin peptides. The entericidin locus is activated in stationary phase under high osmolarity conditions by rho-S and simultaneously repressed by the osmoregulatory EnvZ/OmpR signal transduction pathway. The entericidin locus encodes tandem paralogous genes (ecnAB) and directs the synthesis of two small cell-envelope lipoproteins which can maintain plasmids in bacterial population by means of post-segregational killing.


Pssm-ID: 429826  Cd Length: 20  Bit Score: 31.11  E-value: 1.59e-03
                         10        20
                 ....*....|....*....|
gi 446900496  21 TARGFGEDIKHLGNSISRAA 40
Cdd:pfam08085  1 TVEGAGQDIQAGGEAIEDAA 20
 
Name Accession Description Interval E-value
PRK09810 PRK09810
lipoprotein antitoxin entericidin A;
1-41 2.67e-09

lipoprotein antitoxin entericidin A;


Pssm-ID: 137533  Cd Length: 41  Bit Score: 46.16  E-value: 2.67e-09
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 446900496  1 MMKRLILLALLASTLLTGCNTARGFGEDIKHLGNSISRAAS 41
Cdd:PRK09810  1 MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS 41
COG5510 COG5510
Predicted small secreted protein [Function unknown];
18-41 5.05e-07

Predicted small secreted protein [Function unknown];


Pssm-ID: 444261  Cd Length: 45  Bit Score: 40.22  E-value: 5.05e-07
                        10        20
                ....*....|....*....|....
gi 446900496 18 GCNTARGFGEDIKHLGNSISRAAS 41
Cdd:COG5510  19 GCNTVKGAGEDIESGGEAIEDAAE 42
PRK10081 PRK10081
lipoprotein toxin entericidin B;
19-41 9.65e-04

lipoprotein toxin entericidin B;


Pssm-ID: 170240  Cd Length: 48  Bit Score: 32.36  E-value: 9.65e-04
                        10        20
                ....*....|....*....|...
gi 446900496 19 CNTARGFGEDIKHLGNSISRAAS 41
Cdd:PRK10081 22 CNTTRGVGEDISDGGNAISGAAT 44
Entericidin pfam08085
Entericidin EcnA/B family; This family consists of the entericidin antidote/toxin peptides. ...
 21-40 1.59e-03

Entericidin EcnA/B family; This family consists of the entericidin antidote/toxin peptides. The entericidin locus is activated in stationary phase under high osmolarity conditions by rho-S and simultaneously repressed by the osmoregulatory EnvZ/OmpR signal transduction pathway. The entericidin locus encodes tandem paralogous genes (ecnAB) and directs the synthesis of two small cell-envelope lipoproteins which can maintain plasmids in bacterial population by means of post-segregational killing.


Pssm-ID: 429826  Cd Length: 20  Bit Score: 31.11  E-value: 1.59e-03
                         10        20
                 ....*....|....*....|
gi 446900496  21 TARGFGEDIKHLGNSISRAA 40
Cdd:pfam08085  1 TVEGAGQDIQAGGEAIEDAA 20
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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