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Conserved domains on  [gi|446909707|ref|WP_000986963|]
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MULTISPECIES: conjugative transfer relaxase/helicase TraI [Enterobacteriaceae]

Protein Classification

conjugative transfer relaxase/helicase TraI( domain architecture ID 11486805)

conjugative transfer relaxase/helicase TraI is the central catalytic component of the multiprotein relaxosome complex responsible for conjugative DNA transfer (CDT) between bacterial cells

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK13709 PRK13709
conjugal transfer nickase/helicase TraI; Provisional
2-1751 0e+00

conjugal transfer nickase/helicase TraI; Provisional


:

Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 3078.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    2 MSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGKLPDGADLSRMQDGSNKHRPGYD 81
Cdd:PRK13709    1 MSIAQVKSAGSAGNYYTDKDNYYVLGSMGERWAGEGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   82 LTFSAPKSVSVMAMLGGDKRLIDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAV 161
Cdd:PRK13709   81 LTFSAPKSVSMMAMLGGDKRLIEAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHAV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  162 VANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVPVEAFSGRSQAI 241
Cdd:PRK13709  161 VANVTQHNGKWKTLSSDKVGKTGFIENVYANQIAFGKIYREALKEDVEALGYETEVVGKHGMWEMKGVPVEAFSSRSQEI 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  242 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQTPGPASQDGPDVQQAVT 321
Cdd:PRK13709  241 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYREAADQRAEIRTQAPGPASQDGPDIQQAVT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  322 QAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 401
Cdd:PRK13709  321 QAIAGLSDRKVQFTYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  402 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQIIAADRRSQMNLKQDER 481
Cdd:PRK13709  401 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQILAADRRSQMNLKQDER 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  482 LSGELITGRRQLQEGMAFTPGNTVIVDQGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQ 561
Cdd:PRK13709  481 LSGELITGRRQLQEGMAFTPGSTLIVDQAEKLSLKETLTLLDGAARHNVQVLILDSGQRTGTGSALMVLKDAGVNTYRWQ 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  562 GGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGRPEVTMTALSPVWLDS 641
Cdd:PRK13709  561 GGEQRPATVISEPDKNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTGLIRSALKTQGVLGRPEVTITALSPVWLDS 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  642 RSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSNSLTLRDAQDETQVVRISSLDSSWSLFRPEKMPVADGERLRVT 721
Cdd:PRK13709  641 KSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVKISSLDSSWSLFRPEKMPVADGERLRVL 720
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  722 GKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPASLPVSDSPFMALKLENGWVETPGHSVSDSAKVFASVTQMAMDNAT 801
Cdd:PRK13709  721 GKIPGLRLKGGDRLQVTSVSEDGLTVVVPGRAEPATLPVDDSPFTALKLEHGWVETPGHSVSDSATVFASVTQRAMDNAT 800
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  802 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETLLETAISLQKTGLHTPAQQAIHLALPVVESKNLA 881
Cdd:PRK13709  801 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETDLETAISLQKAGLHTPAQQAIHLALPVLESKNLA 880
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  882 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 961
Cdd:PRK13709  881 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 960
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  962 PGELMEKLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1041
Cdd:PRK13709  961 PGELMEGLTSGQRAATRMILESTDRFTVVQGYAGVGKTTQFRAVMSAVNTLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1040
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1042 TLASFLHDTQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAA 1121
Cdd:PRK13709 1041 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVSSGDTDQLQAIAPGQPFRLMQTRSAA 1120
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1122 DVVIMKEIVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLkgeAF 1201
Cdd:PRK13709 1121 DVAIMKEIVRQTPELREAVYSLINRDVERALSGIESVKPSQVPRQEGAWAPESSVTEFSHPQEAKLAEAQQKAML---AF 1197
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1202 PDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWE 1281
Cdd:PRK13709 1198 PDVPMTLYEAIVRDYTGRTPEAREQTLIITHLNEDRRVLNSMIHDAREKAGELGKEQVTVPVLDTANIRDGELRRLSTWE 1277
                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1282 NNPDALALVDSVYHRIAGISKDDGLITLEDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1361
Cdd:PRK13709 1278 AHRGALALVDNVYHRIAGIDKDDGLITLRDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1357
                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1362 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLMAGFESAYVALSRMKQ 1441
Cdd:PRK13709 1358 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETYAIALEGTEGGRKQMAGFESAYVALSRMKQ 1437
                        1450      1460      1470      1480      1490      1500      1510      1520
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1442 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKSDREVMNAERLFSTARELRDVVAGRAVLRQAGLAGGDSPARFIAPGRK 1521
Cdd:PRK13709 1438 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAERLFSTARELRDTAAGRAVLRQAGLAGGDSPARFIAPGRK 1517
                        1530      1540      1550      1560      1570      1580      1590      1600
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1522 YPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1601
Cdd:PRK13709 1518 YPQPHVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSEDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1597
                        1610      1620      1630      1640      1650      1660      1670      1680
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1602 GVVVRIAGEGRPWNPRTITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1681
Cdd:PRK13709 1598 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1677
                        1690      1700      1710      1720      1730      1740      1750
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1682 GKTEQAVRDIAGLERDRSAISEREAALPESVLREPQRVREAVREVARENLLQERLQQMERDMVRDLQKEK 1751
Cdd:PRK13709 1678 GKTEQAVRDIAGQERDRAAISEREAALPESVLREPQREREAVREVARENLLRERLQQMERDMVRDLQKEK 1747
 
Name Accession Description Interval E-value
PRK13709 PRK13709
conjugal transfer nickase/helicase TraI; Provisional
2-1751 0e+00

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 3078.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    2 MSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGKLPDGADLSRMQDGSNKHRPGYD 81
Cdd:PRK13709    1 MSIAQVKSAGSAGNYYTDKDNYYVLGSMGERWAGEGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   82 LTFSAPKSVSVMAMLGGDKRLIDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAV 161
Cdd:PRK13709   81 LTFSAPKSVSMMAMLGGDKRLIEAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHAV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  162 VANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVPVEAFSGRSQAI 241
Cdd:PRK13709  161 VANVTQHNGKWKTLSSDKVGKTGFIENVYANQIAFGKIYREALKEDVEALGYETEVVGKHGMWEMKGVPVEAFSSRSQEI 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  242 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQTPGPASQDGPDVQQAVT 321
Cdd:PRK13709  241 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYREAADQRAEIRTQAPGPASQDGPDIQQAVT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  322 QAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 401
Cdd:PRK13709  321 QAIAGLSDRKVQFTYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  402 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQIIAADRRSQMNLKQDER 481
Cdd:PRK13709  401 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQILAADRRSQMNLKQDER 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  482 LSGELITGRRQLQEGMAFTPGNTVIVDQGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQ 561
Cdd:PRK13709  481 LSGELITGRRQLQEGMAFTPGSTLIVDQAEKLSLKETLTLLDGAARHNVQVLILDSGQRTGTGSALMVLKDAGVNTYRWQ 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  562 GGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGRPEVTMTALSPVWLDS 641
Cdd:PRK13709  561 GGEQRPATVISEPDKNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTGLIRSALKTQGVLGRPEVTITALSPVWLDS 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  642 RSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSNSLTLRDAQDETQVVRISSLDSSWSLFRPEKMPVADGERLRVT 721
Cdd:PRK13709  641 KSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVKISSLDSSWSLFRPEKMPVADGERLRVL 720
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  722 GKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPASLPVSDSPFMALKLENGWVETPGHSVSDSAKVFASVTQMAMDNAT 801
Cdd:PRK13709  721 GKIPGLRLKGGDRLQVTSVSEDGLTVVVPGRAEPATLPVDDSPFTALKLEHGWVETPGHSVSDSATVFASVTQRAMDNAT 800
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  802 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETLLETAISLQKTGLHTPAQQAIHLALPVVESKNLA 881
Cdd:PRK13709  801 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETDLETAISLQKAGLHTPAQQAIHLALPVLESKNLA 880
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  882 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 961
Cdd:PRK13709  881 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 960
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  962 PGELMEKLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1041
Cdd:PRK13709  961 PGELMEGLTSGQRAATRMILESTDRFTVVQGYAGVGKTTQFRAVMSAVNTLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1040
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1042 TLASFLHDTQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAA 1121
Cdd:PRK13709 1041 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVSSGDTDQLQAIAPGQPFRLMQTRSAA 1120
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1122 DVVIMKEIVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLkgeAF 1201
Cdd:PRK13709 1121 DVAIMKEIVRQTPELREAVYSLINRDVERALSGIESVKPSQVPRQEGAWAPESSVTEFSHPQEAKLAEAQQKAML---AF 1197
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1202 PDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWE 1281
Cdd:PRK13709 1198 PDVPMTLYEAIVRDYTGRTPEAREQTLIITHLNEDRRVLNSMIHDAREKAGELGKEQVTVPVLDTANIRDGELRRLSTWE 1277
                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1282 NNPDALALVDSVYHRIAGISKDDGLITLEDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1361
Cdd:PRK13709 1278 AHRGALALVDNVYHRIAGIDKDDGLITLRDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1357
                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1362 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLMAGFESAYVALSRMKQ 1441
Cdd:PRK13709 1358 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETYAIALEGTEGGRKQMAGFESAYVALSRMKQ 1437
                        1450      1460      1470      1480      1490      1500      1510      1520
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1442 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKSDREVMNAERLFSTARELRDVVAGRAVLRQAGLAGGDSPARFIAPGRK 1521
Cdd:PRK13709 1438 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAERLFSTARELRDTAAGRAVLRQAGLAGGDSPARFIAPGRK 1517
                        1530      1540      1550      1560      1570      1580      1590      1600
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1522 YPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1601
Cdd:PRK13709 1518 YPQPHVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSEDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1597
                        1610      1620      1630      1640      1650      1660      1670      1680
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1602 GVVVRIAGEGRPWNPRTITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1681
Cdd:PRK13709 1598 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1677
                        1690      1700      1710      1720      1730      1740      1750
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1682 GKTEQAVRDIAGLERDRSAISEREAALPESVLREPQRVREAVREVARENLLQERLQQMERDMVRDLQKEK 1751
Cdd:PRK13709 1678 GKTEQAVRDIAGQERDRAAISEREAALPESVLREPQREREAVREVARENLLRERLQQMERDMVRDLQKEK 1747
TraI_TIGR TIGR02760
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ...
1-1756 0e+00

conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.


Pssm-ID: 274285 [Multi-domain]  Cd Length: 1960  Bit Score: 1985.14  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707     1 MMSIAQVRSAGSAGNYYTDKDNYYVLGSM---GERWAGRGAEQLGLQG-SVDKDVFTRLLEGKLPDGADLSRMQDGSNKH 76
Cdd:TIGR02760    1 MMSISPLRSAGDAAAYYLDEDNYYLKDSKslnNTRWLGKGAEQLGLLGkPVEKEQFEALLSGTLPDGTQLGRIDKGGIHH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    77 RPGYDLTFSAPKSVSVMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQ 155
Cdd:TIGR02760   81 RPGFDLTFSAPKSVSILALVGGDKRLIEAHDKAVKIAVSEMEKdAAQARQTVDGKTEFINTRNLVFAMFRHKTSRENDPQ 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   156 LHTHAVVANVTQ-HNGEWKTLSSDKVGKTGFI----ENVYANQIAFGRLYREKLKEQVEALGYETEVVGKhGMWEMPGVP 230
Cdd:TIGR02760  161 LHTHAVVQNMTHdSDGKWRSLASDMKGQKGVIegfrERIYNHQIYYGLLYRSKLAKKVEELGYQTASVGK-GQFEIQGVP 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   231 ---VEAFSGRSQAIREAVGEDA--SLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQT 305
Cdd:TIGR02760  240 eqvLTAFSKRRQQIDELVDEKGwsSAKARDIAALDTRKDKTYIDDETLMEKWQQECKDMGFDPHALVASSYKPENIVARF 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   306 PGPASQDgpdVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIER--ARAGIDEAISREQLIPLDREKGLFTSG 383
Cdd:TIGR02760  320 YGPSQID---AQHAVEVAIAHLSQYSTQFEYEKLIEEAAKYFTAGNKIIDEidIKKAIDELIANGQLIPLFTQKGLFTTQ 396
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   384 IHVLDELSVRALSRDIMKQNRVTVHPEKSV--PRTAGYSDAVSVLAQDRPSLAIVSGQGGAaGQRERVAELVMMAREQGR 461
Cdd:TIGR02760  397 TMLTNEKELIARTEGGKGALRVIVSKQKLSefALSPSNKDAVSTLFTSTKRFIIINGFGGT-GSTEIAQLLLHLASEQGY 475
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   462 EVQIIAADRRSQMNLKQD-ERLSGELITGRRQLQEGM-------------AFTPGNTVIVDQGEKLSLKETLTLLDGAAR 527
Cdd:TIGR02760  476 EIQIITAGSLSAQELRQKiPRLASTFITWVKNLFNDDqdhtvqglldkssPFSNKDIFVVDEANKLSNNELLKLIDKAEQ 555
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   528 HNVQ-VLITDSGQRTG--TGSALMAMKDAGVNTYRWQGGEQRPATI-ISEPDRNVRYARLAGDFAASVKAGEESVAQVSG 603
Cdd:TIGR02760  556 HNSKlILLNDSAQRQGmsAGSAIDLLKEGGVTTYAWVDTKQQKASVeISEAVDKLRVDYIASAWLDLTPDRQNSQVLATT 635
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   604 VREQAILTQAIRSELKTQGVLGRPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSNSLTL 683
Cdd:TIGR02760  636 HREQQDLTQIIRNALKQEGQLSRQEVTVPTLKPVNLTGIQRRNAAHYKQGMVIRFWQKGKIPHDDYVVTNVNKHNNTLTL 715
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   684 RDAQDETQVVRISSL---DSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVV-VPGRaepaSLP 759
Cdd:TIGR02760  716 KDAQGKTQKFKPSSLkdlERPFSVYRPEQLEVAAGERLQVTGNHFHSRVRNGELLTVSSINNEGITLItEDGQ----TLH 791
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   760 VSDSPFMALKLENGWVETPGHSVSDSAKVFASVTQMAMDNATLNGLARSGRDVRLYSSLDET--RTAEKLARHPSFTVVS 837
Cdd:TIGR02760  792 LPHGALEDAHLDYGYVLTPYHTQPDDAKVFLGVKQYALSKALLNSLNRSASRVDLFTDLDEKaqRYLEKTRGIPSAIVVV 871
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   838 EQIKARAGETL-------LETAISLQKTGLHTPAQQ-----AIHLALPVVESKNLAFSMVDLLTEAKSFAAEGTSFTELG 905
Cdd:TIGR02760  872 DQKQHLPDAVTtnntdksLEMDISDTLHALEAKAKDgknsiALQYALEKVSEKEAAFKQKELVTEAYVFAFEETGFAIKA 951
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   906 GEINAQIKRGDLLYVDVAKGYGTG-LLVSRASYEAEKSILRHILEGKEAVTPLMERVPG----ELMEKLTSGQRAATRMI 980
Cdd:TIGR02760  952 AEIAAALKNRPKLYRLLSAEYGDGtRWTTRAALRTETSILLHILPGKETVTPLATRAQVflnlELLERLTHGQKQAIHLI 1031
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   981 LETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLLQRSGEtp 1060
Cdd:TIGR02760 1032 ISTKDRFVAVQGLAGVGKTTMLESRYKPVLQAFESEQLQVIGLAPTHEAVGELKSAGVQAQTLDSFLTDISLYRNSGG-- 1109
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1061 NFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQ--TPELRE 1138
Cdd:TIGR02760 1110 DFRNTLFILDESSMVSNFQLTHATELVQKSGSRAVSLGDIAQLQSLAAGKPFELAITFDIIDTAIMKEIVRQnnSAELKA 1189
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1139 AVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHsQEAKLAEAQQKAMLKGEAFPDIPMTLYEAIVRDYTG 1218
Cdd:TIGR02760 1190 AHNSLDKRSNPKALELLKNQNPLQHELMQNAAMPEIASDEQGL-QKHDLAKLAVNTEKPKKAQPDATVTLYREIVKDYLS 1268
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1219 RTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWENNpDALALVDSVYHRIA 1298
Cdd:TIGR02760 1269 RTPEFRENTLIIAHTNNDRTGIYPFIREGLIKQKELSKQQVTVPRLRSVNISSPELKTMMPFEKG-AVLRLKKDAYLTIA 1347
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1299 GISKDDGLITLEDAE-GNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSVWTVTAV-SGDSVTLSD 1376
Cdd:TIGR02760 1348 DIDREHGKLTVADIKtGSERDILPRQLDHTFTSLYSDSELPLAKGDKIRLRATDKNRGIKANEVYTVTQVvNGLSVQLSK 1427
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1377 GQQTRVIRPGQERaEQHIDLAYAITAHGAQGASETFAIALegtEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWT-- 1454
Cdd:TIGR02760 1428 VKNSLSLKPIQAK-DKHWDYAYTRTADSAQGATYTFVIAL---IKGRLALTNYRSAYIDLTRASHHVELYTDNKEGTVks 1503
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1455 ---------------------------------------------------DAINNAV---------------------- 1461
Cdd:TIGR02760 1504 wkqreanktsaveteedyrpkqstqfnnraqpheepkyqqkngplkiqsaaEIINEALpayteslaktllgepntqksrr 1583
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1462 -----------------------------QKGTAHDVLEPKSD---REVMN----------------------------- 1480
Cdd:TIGR02760 1584 drytfgakgglkvsltgkyrglwhdfstgEKGTLIQLIEAKKGlsfKEALNqaasllgipqhyqlsinikapqlsntepq 1663
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1481 --------AERLFSTARELRDVVAGRAVLRQAGLAGGDSPARFIAP-----GRKYPQPYVALPAFDRNGKSAGIWLNPLT 1547
Cdd:TIGR02760 1664 klnqlekrAKSLFQGSQELKGTLAEKYLKQHRGLASIDNDDIRFHPtvyssDKKNKHPALIAAARNEKGEITGIQITYLD 1743
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1548 TDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGE-SLLADNMQDGVRIARDNPDSGVVVRIAGegrpwnprtitggrvwg 1626
Cdd:TIGR02760 1744 KDDANKDKDMDNNKRVKGSISGQFVVINKGMQGDrSYIAEGIETGLSIALANPKATVVIAVGG----------------- 1806
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1627 dipDNSVQPGAGNGEPVTAEVLAQRQAEEAIrreTERRADEIVRKMAENK-----------PDLPDGKTEQAVRDIAGLE 1695
Cdd:TIGR02760 1807 ---KNNLSPIIPKFIPKNVVIVLDNDGEEAK---SQRAIEKIINKFKQDNisarivfpddwNDIGEEELQKQLMRAISSI 1880
                         1930      1940      1950      1960      1970      1980
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446909707  1696 RDRSAISEREAALPESVLREPQRVREAVREVARENLLQERLQQM-------ERDMVRDLQKEKTLGGD 1756
Cdd:TIGR02760 1881 EDKDIEIPKAIADFESVLKMPNSDIISIIDNARTEREKSDLEQIvanehksQQALERDLNKEFTPDKR 1948
MobF NF041492
MobF family relaxase;
1-281 4.84e-112

MobF family relaxase;


Pssm-ID: 469380 [Multi-domain]  Cd Length: 288  Bit Score: 357.38  E-value: 4.84e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    1 MMSIAQVRSAGSAGNYYTDKD--NYYVLG--SMGERWAGRGAEQLGL-QGSVDKDVFTRLLEGKLPDGADLSRMQDGSNK 75
Cdd:NF041492    1 MLSIARIGSAGGAARYYTEKDldNYYSEDggTPAGRWFGKGAEALGLsGGAVDGERFKALLDGRLPDGERLRRRRKGAGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   76 HRPGYDLTFSAPKSVSVMAMLGGDKRLIDAHNQAVDFAVR-QVEALASTRVMTDGQSETVL--TGNLVMALFNHDTSRDQ 152
Cdd:NF041492   81 HRPGYDLTFSAPKSVSLLALVGGDKRLIEAHDEAVKEALEyLEERLAQTRVTVDGKGRTSLekTGNLVAALFRHDTSRAG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  153 EPQLHTHAVVANVTQH-NGEWKTLSSdkvgktgfiENVYANQIAFGRLYREKLKEQVEALGYETEVVgKHGMWEMPGVP- 230
Cdd:NF041492  161 DPQLHTHAVVMNMTQRpDGKWRSLDN---------EELYKNQKALGAIYQAELAEELQALGYEIRET-KNGQFEIAGVPr 230
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446909707  231 --VEAFSGRSQAIREAVGED----ASLKSRDVAALDTRKSKQ-HVDPEVRMAEWMQTL 281
Cdd:NF041492  231 eqIEAFSKRSQQIEEWLGENpatlASAALRQIAALDTRKAKEaDVDPEELEAEWREEA 288
TrwC pfam08751
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative ...
10-283 1.37e-97

TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.


Pssm-ID: 430190 [Multi-domain]  Cd Length: 279  Bit Score: 315.71  E-value: 1.37e-97
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    10 AGSAGNYYTDKDNYYVL-GSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGKLPD-GADLSRMQDGSNKHRPGYDLTFSAP 87
Cdd:pfam08751    1 AGDAYAYYTRQDDYYTEgGEPPGRWLGKGAAALGLSGEVTEEQFEALLEGRHPDtGERLGRRRPRGRKHRAGFDLTFSAP 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    88 KSVSVMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAVVANVT 166
Cdd:pfam08751   81 KSVSLLAAVGGDERIEAAHRAAVAEALAWLEKhAAQTRVGKDGGVEQVDTGGLVAAAFRHDTSRAGDPQLHTHVVVANVT 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   167 Q-HNGEWKTLSSDKvgktgfienVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIR 242
Cdd:pfam08751  161 QrEDGKWRALDSRG---------LYKAQVAAGAVYRAELADELRRLGYEIEERGKRGVFEIAGVPeelIEAFSKRRAQIE 231
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 446909707   243 EAVGE------DASLKSRDVAALDTRKSK-QHVDPEVRMAEWMQTLKE 283
Cdd:pfam08751  232 AELAElgathgRAPPAARQIAALETRPAKhEPRSLAELRARWREEAAE 279
RecD COG0507
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ...
937-1468 1.86e-51

ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];


Pssm-ID: 440273 [Multi-domain]  Cd Length: 514  Bit Score: 190.96  E-value: 1.86e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  937 YEAEKSILRHILEGK------EAVTPLMERVPGELMEKLTSGQRAATRMILETSdRFTVVQGYAGVGKTTqfraVMSAVN 1010
Cdd:COG0507    87 LEAEQRLARRLRRLArpaldeADVEAALAALEPRAGITLSDEQREAVALALTTR-RVSVLTGGAGTGKTT----TLRALL 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1011 MLPESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFLH---DTQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYAL 1086
Cdd:COG0507   162 AALEALGLRVALAAPTGKAAKRLSeSTGIEARTIHRLLGlrpDSGRFRHNRDNPLTPADLLVVDEASMVDTRLMAALLEA 241
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1087 IAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELREAVYS-LINR-DVERALSglesvkpsqvp 1164
Cdd:COG0507   242 LPRAGARLILVGDPDQLPSVGAGAVLRDLIESGTVPVVELTEVYRQADDSRIIELAhAIREgDAPEALN----------- 310
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1165 rqegAWAPEHSVTEFSHSQEAKlaeaqqkamlkgeafpdipmtlyEAIVRDYTGRtPEAREQTLIVTHLNEDRRVLNSMI 1244
Cdd:COG0507   311 ----ARYADVVFVEAEDAEEAA-----------------------EAIVELYADR-PAGGEDIQVLAPTNAGVDALNQAI 362
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1245 HDAREKAGELGKEQvmvpvlntanIRDGELRrlstwennpdalalvdsvyhriagiskddglitledaegntrlisprea 1324
Cdd:COG0507   363 REALNPAGELEREL----------AEDGELE------------------------------------------------- 383
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1325 vaegvtlytpdtIRVgtGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLS---DGQQTRVIRPGQERaeqHIDLAYAIT 1401
Cdd:COG0507   384 ------------LYV--GDRVMFTRNDYDLGVFNGDIGTVLSIDEDEGRLTvrfDGREIVTYDPSELD---QLELAYAIT 446
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446909707 1402 AHGAQGAseTF--AIALEGTEGNRklMAGFESAYVALSRMKQHVQVYTDNRQgWTDAINNAVQKGTAHD 1468
Cdd:COG0507   447 VHKSQGS--TFdrVILVLPSEHSP--LLSRELLYTALTRARELLTLVGDRDA-LARAVRRDTARATGLA 510
DEXSc_RecD-like cd17933
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ...
972-1130 1.53e-38

DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350691 [Multi-domain]  Cd Length: 155  Bit Score: 141.54  E-value: 1.53e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  972 GQRAATRMILetSDRFTVVQGYAGVGKTTQFRAVMSAVnmlpESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFLHDT 1050
Cdd:cd17933     1 EQKAAVRLVL--RNRVSVLTGGAGTGKTTTLKALLAAL----EAEGKRVVLAAPTGKAAKRLSeSTGIEASTIHRLLGIN 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1051 QLLQRS--GETPNFSNTLFLLDESSMVGNTDMARAYALIAAGGgRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKE 1128
Cdd:cd17933    75 PGGGGFyyNEENPLDADLLIVDEASMVDTRLMAALLSAIPAGA-RLILVGDPDQLPSVGAGNVLRDLIASKGVPTVELTE 153

                  ..
gi 446909707 1129 IV 1130
Cdd:cd17933   154 VF 155
 
Name Accession Description Interval E-value
PRK13709 PRK13709
conjugal transfer nickase/helicase TraI; Provisional
2-1751 0e+00

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237478 [Multi-domain]  Cd Length: 1747  Bit Score: 3078.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    2 MSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGKLPDGADLSRMQDGSNKHRPGYD 81
Cdd:PRK13709    1 MSIAQVKSAGSAGNYYTDKDNYYVLGSMGERWAGEGAEQLGLQGSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   82 LTFSAPKSVSVMAMLGGDKRLIDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAV 161
Cdd:PRK13709   81 LTFSAPKSVSMMAMLGGDKRLIEAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHAV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  162 VANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVPVEAFSGRSQAI 241
Cdd:PRK13709  161 VANVTQHNGKWKTLSSDKVGKTGFIENVYANQIAFGKIYREALKEDVEALGYETEVVGKHGMWEMKGVPVEAFSSRSQEI 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  242 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQTPGPASQDGPDVQQAVT 321
Cdd:PRK13709  241 REAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYREAADQRAEIRTQAPGPASQDGPDIQQAVT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  322 QAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 401
Cdd:PRK13709  321 QAIAGLSDRKVQFTYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSVRALSRDIMK 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  402 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQIIAADRRSQMNLKQDER 481
Cdd:PRK13709  401 QNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELVMMAREQGREVQILAADRRSQMNLKQDER 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  482 LSGELITGRRQLQEGMAFTPGNTVIVDQGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQ 561
Cdd:PRK13709  481 LSGELITGRRQLQEGMAFTPGSTLIVDQAEKLSLKETLTLLDGAARHNVQVLILDSGQRTGTGSALMVLKDAGVNTYRWQ 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  562 GGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGRPEVTMTALSPVWLDS 641
Cdd:PRK13709  561 GGEQRPATVISEPDKNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTGLIRSALKTQGVLGRPEVTITALSPVWLDS 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  642 RSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSNSLTLRDAQDETQVVRISSLDSSWSLFRPEKMPVADGERLRVT 721
Cdd:PRK13709  641 KSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVKISSLDSSWSLFRPEKMPVADGERLRVL 720
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  722 GKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPASLPVSDSPFMALKLENGWVETPGHSVSDSAKVFASVTQMAMDNAT 801
Cdd:PRK13709  721 GKIPGLRLKGGDRLQVTSVSEDGLTVVVPGRAEPATLPVDDSPFTALKLEHGWVETPGHSVSDSATVFASVTQRAMDNAT 800
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  802 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETLLETAISLQKTGLHTPAQQAIHLALPVVESKNLA 881
Cdd:PRK13709  801 LNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETDLETAISLQKAGLHTPAQQAIHLALPVLESKNLA 880
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  882 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 961
Cdd:PRK13709  881 FSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERV 960
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  962 PGELMEKLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1041
Cdd:PRK13709  961 PGELMEGLTSGQRAATRMILESTDRFTVVQGYAGVGKTTQFRAVMSAVNTLPESERPRVVGLGPTHRAVGEMRSAGVDAQ 1040
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1042 TLASFLHDTQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAA 1121
Cdd:PRK13709 1041 TLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVSSGDTDQLQAIAPGQPFRLMQTRSAA 1120
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1122 DVVIMKEIVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLkgeAF 1201
Cdd:PRK13709 1121 DVAIMKEIVRQTPELREAVYSLINRDVERALSGIESVKPSQVPRQEGAWAPESSVTEFSHPQEAKLAEAQQKAML---AF 1197
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1202 PDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWE 1281
Cdd:PRK13709 1198 PDVPMTLYEAIVRDYTGRTPEAREQTLIITHLNEDRRVLNSMIHDAREKAGELGKEQVTVPVLDTANIRDGELRRLSTWE 1277
                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1282 NNPDALALVDSVYHRIAGISKDDGLITLEDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1361
Cdd:PRK13709 1278 AHRGALALVDNVYHRIAGIDKDDGLITLRDAEGNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSV 1357
                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1362 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLMAGFESAYVALSRMKQ 1441
Cdd:PRK13709 1358 WTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETYAIALEGTEGGRKQMAGFESAYVALSRMKQ 1437
                        1450      1460      1470      1480      1490      1500      1510      1520
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1442 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKSDREVMNAERLFSTARELRDVVAGRAVLRQAGLAGGDSPARFIAPGRK 1521
Cdd:PRK13709 1438 HVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAERLFSTARELRDTAAGRAVLRQAGLAGGDSPARFIAPGRK 1517
                        1530      1540      1550      1560      1570      1580      1590      1600
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1522 YPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1601
Cdd:PRK13709 1518 YPQPHVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSEDAQFVALQGSRNGESLLADNMQDGVRIARDNPDS 1597
                        1610      1620      1630      1640      1650      1660      1670      1680
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1602 GVVVRIAGEGRPWNPRTITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1681
Cdd:PRK13709 1598 GVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENKPDLPD 1677
                        1690      1700      1710      1720      1730      1740      1750
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1682 GKTEQAVRDIAGLERDRSAISEREAALPESVLREPQRVREAVREVARENLLQERLQQMERDMVRDLQKEK 1751
Cdd:PRK13709 1678 GKTEQAVRDIAGQERDRAAISEREAALPESVLREPQREREAVREVARENLLRERLQQMERDMVRDLQKEK 1747
PRK14712 PRK14712
conjugal transfer nickase/helicase TraI; Provisional
134-1756 0e+00

conjugal transfer nickase/helicase TraI; Provisional


Pssm-ID: 237796 [Multi-domain]  Cd Length: 1623  Bit Score: 3004.73  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  134 VLTGNLVMALFNHDTSRDQEPQLHTHAVVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGY 213
Cdd:PRK14712    1 VLTGNLVMALFNHDTSRDQEPQLHTHAVVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGY 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  214 ETEVVGKHGMWEMPGVPVEAFSGRSQAIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRD 293
Cdd:PRK14712   81 ETEVVGKHGMWEMPGVPVEAFSGRSQTIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRD 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  294 AADQRAETRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPL 373
Cdd:PRK14712  161 AAEQRAYTRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQFMYTDLLARTVGILPPENGVIERARAGIDEAISREQLIPL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  374 DREKGLFTSGIHVLDELSVRALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELV 453
Cdd:PRK14712  241 DREKGLFTSGIHMLDELSVRALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVAELV 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  454 MMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLQEGMAFTPGNTVIVDQGEKLSLKETLTLLDGAARHNVQVL 533
Cdd:PRK14712  321 MMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLLEGMAFTPGSTVIVDQGEKLSLKETLTLLDGAARHNVQVL 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  534 ITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQA 613
Cdd:PRK14712  401 ITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQA 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  614 IRSELKTQGVLGRPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSNSLTLRDAQDETQVV 693
Cdd:PRK14712  481 IRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVTERVTAQSHSLTLRNAQGETQVV 560
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  694 RISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPASLPVSDSPFMALKLENG 773
Cdd:PRK14712  561 RISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPATLPVSDSPFTALKLENG 640
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  774 WVETPGHSVSDSAKVFASVTQMAMDNATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETLLETAI 853
Cdd:PRK14712  641 WVETPGHSVSDSATVFASVTQMAMDNATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETLLETAI 720
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  854 SLQKTGLHTPAQQAIHLALPVVESKNLAFSMVDLLTEAKSFAAEGTSFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVS 933
Cdd:PRK14712  721 SLQKAGLHTPAQQAIHLALPVLESKNLAFSMVDLLTEAKSFAAEGTGFADLGGEINAQIKRGDLLYVDVAKGYGTGLLVS 800
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  934 RASYEAEKSILRHILEGKEAVTPLMERVPGELMEKLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLP 1013
Cdd:PRK14712  801 RASYEAEKSILRHILEGKEAVTPLMERVPGELMEKLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLP 880
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1014 ESERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYALIAAGGGR 1093
Cdd:PRK14712  881 ESERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGR 960
                         970       980       990      1000      1010      1020      1030      1040
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1094 AVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPE 1173
Cdd:PRK14712  961 AVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELREAVYSLINRDVERALSGLERVKPSQVPRLEGAWAPE 1040
                        1050      1060      1070      1080      1090      1100      1110      1120
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1174 HSVTEFSHSQEAKLAEAQQKAMLKGEAFPDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGE 1253
Cdd:PRK14712 1041 HSVTEFSHSQEAKLAEAQQKAMLKGEAFPDVPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGE 1120
                        1130      1140      1150      1160      1170      1180      1190      1200
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1254 LGKEQVMVPVLNTANIRDGELRRLSTWENNPDALALVDSVYHRIAGISKDDGLITLEDAEGNTRLISPREAVAEGVTLYT 1333
Cdd:PRK14712 1121 LGQVQVMVPVLNTANIRDGELRRLSTWENNPDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLISPREAVAEGVTLYT 1200
                        1210      1220      1230      1240      1250      1260      1270      1280
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1334 PDTIRVGTGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFA 1413
Cdd:PRK14712 1201 PDTIRVGTGDRIRFTKSDRERGYVANSVWTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGASETFA 1280
                        1290      1300      1310      1320      1330      1340      1350      1360
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1414 IALEGTEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKSDREVMNAERLFSTARELRD 1493
Cdd:PRK14712 1281 IALEGTEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVFEPKPDREVMNAERLFSTARELRD 1360
                        1370      1380      1390      1400      1410      1420      1430      1440
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1494 VVAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVA 1573
Cdd:PRK14712 1361 VAAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVA 1440
                        1450      1460      1470      1480      1490      1500      1510      1520
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1574 LQGSRNGESLLADNMQDGVRIARDNPDSGVVVRIAGEGRPWNPRTITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQA 1653
Cdd:PRK14712 1441 LQGSRNGESLLADNMQDGVRIARDNPDSGVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQA 1520
                        1530      1540      1550      1560      1570      1580      1590      1600
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1654 EEAIRRETERRADEIVRKMAENKPDLPDGKTEQAVRDIAGLERDRSAISEREAALPESVLREPQRVREAVREVARENLLQ 1733
Cdd:PRK14712 1521 EEAIRRETERRADEIVRKMAENKPDLPDGKTEQAVREIAGQERDRAAITEREAALPESVLREPQRVREAVREVARENLLQ 1600
                        1610      1620
                  ....*....|....*....|...
gi 446909707 1734 ERLQQMERDMVRDLQKEKTLGGD 1756
Cdd:PRK14712 1601 ERLQQMERDMVRDLQKEKTPGGD 1623
TraI_TIGR TIGR02760
conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome ...
1-1756 0e+00

conjugative transfer relaxase protein TraI; This protein is a component of the relaxosome complex. In the process of conjugative plasmid transfer the realaxosome binds to the plasmid at the oriT (origin of transfer) site. The relaxase protein TraI mediates the single-strand nicking and ATP-dependent unwinding (relaxation, helicase activity) of the plasmid molecule. These two activities reside in separate domains of the protein.


Pssm-ID: 274285 [Multi-domain]  Cd Length: 1960  Bit Score: 1985.14  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707     1 MMSIAQVRSAGSAGNYYTDKDNYYVLGSM---GERWAGRGAEQLGLQG-SVDKDVFTRLLEGKLPDGADLSRMQDGSNKH 76
Cdd:TIGR02760    1 MMSISPLRSAGDAAAYYLDEDNYYLKDSKslnNTRWLGKGAEQLGLLGkPVEKEQFEALLSGTLPDGTQLGRIDKGGIHH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    77 RPGYDLTFSAPKSVSVMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQ 155
Cdd:TIGR02760   81 RPGFDLTFSAPKSVSILALVGGDKRLIEAHDKAVKIAVSEMEKdAAQARQTVDGKTEFINTRNLVFAMFRHKTSRENDPQ 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   156 LHTHAVVANVTQ-HNGEWKTLSSDKVGKTGFI----ENVYANQIAFGRLYREKLKEQVEALGYETEVVGKhGMWEMPGVP 230
Cdd:TIGR02760  161 LHTHAVVQNMTHdSDGKWRSLASDMKGQKGVIegfrERIYNHQIYYGLLYRSKLAKKVEELGYQTASVGK-GQFEIQGVP 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   231 ---VEAFSGRSQAIREAVGEDA--SLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDIRAYRDAADQRAETRTQT 305
Cdd:TIGR02760  240 eqvLTAFSKRRQQIDELVDEKGwsSAKARDIAALDTRKDKTYIDDETLMEKWQQECKDMGFDPHALVASSYKPENIVARF 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   306 PGPASQDgpdVQQAVTQAIAGLSERKVQFTYTDVLARTVGILPPENGVIER--ARAGIDEAISREQLIPLDREKGLFTSG 383
Cdd:TIGR02760  320 YGPSQID---AQHAVEVAIAHLSQYSTQFEYEKLIEEAAKYFTAGNKIIDEidIKKAIDELIANGQLIPLFTQKGLFTTQ 396
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   384 IHVLDELSVRALSRDIMKQNRVTVHPEKSV--PRTAGYSDAVSVLAQDRPSLAIVSGQGGAaGQRERVAELVMMAREQGR 461
Cdd:TIGR02760  397 TMLTNEKELIARTEGGKGALRVIVSKQKLSefALSPSNKDAVSTLFTSTKRFIIINGFGGT-GSTEIAQLLLHLASEQGY 475
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   462 EVQIIAADRRSQMNLKQD-ERLSGELITGRRQLQEGM-------------AFTPGNTVIVDQGEKLSLKETLTLLDGAAR 527
Cdd:TIGR02760  476 EIQIITAGSLSAQELRQKiPRLASTFITWVKNLFNDDqdhtvqglldkssPFSNKDIFVVDEANKLSNNELLKLIDKAEQ 555
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   528 HNVQ-VLITDSGQRTG--TGSALMAMKDAGVNTYRWQGGEQRPATI-ISEPDRNVRYARLAGDFAASVKAGEESVAQVSG 603
Cdd:TIGR02760  556 HNSKlILLNDSAQRQGmsAGSAIDLLKEGGVTTYAWVDTKQQKASVeISEAVDKLRVDYIASAWLDLTPDRQNSQVLATT 635
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   604 VREQAILTQAIRSELKTQGVLGRPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSNSLTL 683
Cdd:TIGR02760  636 HREQQDLTQIIRNALKQEGQLSRQEVTVPTLKPVNLTGIQRRNAAHYKQGMVIRFWQKGKIPHDDYVVTNVNKHNNTLTL 715
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   684 RDAQDETQVVRISSL---DSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASVSEDAMTVV-VPGRaepaSLP 759
Cdd:TIGR02760  716 KDAQGKTQKFKPSSLkdlERPFSVYRPEQLEVAAGERLQVTGNHFHSRVRNGELLTVSSINNEGITLItEDGQ----TLH 791
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   760 VSDSPFMALKLENGWVETPGHSVSDSAKVFASVTQMAMDNATLNGLARSGRDVRLYSSLDET--RTAEKLARHPSFTVVS 837
Cdd:TIGR02760  792 LPHGALEDAHLDYGYVLTPYHTQPDDAKVFLGVKQYALSKALLNSLNRSASRVDLFTDLDEKaqRYLEKTRGIPSAIVVV 871
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   838 EQIKARAGETL-------LETAISLQKTGLHTPAQQ-----AIHLALPVVESKNLAFSMVDLLTEAKSFAAEGTSFTELG 905
Cdd:TIGR02760  872 DQKQHLPDAVTtnntdksLEMDISDTLHALEAKAKDgknsiALQYALEKVSEKEAAFKQKELVTEAYVFAFEETGFAIKA 951
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   906 GEINAQIKRGDLLYVDVAKGYGTG-LLVSRASYEAEKSILRHILEGKEAVTPLMERVPG----ELMEKLTSGQRAATRMI 980
Cdd:TIGR02760  952 AEIAAALKNRPKLYRLLSAEYGDGtRWTTRAALRTETSILLHILPGKETVTPLATRAQVflnlELLERLTHGQKQAIHLI 1031
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   981 LETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLLQRSGEtp 1060
Cdd:TIGR02760 1032 ISTKDRFVAVQGLAGVGKTTMLESRYKPVLQAFESEQLQVIGLAPTHEAVGELKSAGVQAQTLDSFLTDISLYRNSGG-- 1109
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1061 NFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQ--TPELRE 1138
Cdd:TIGR02760 1110 DFRNTLFILDESSMVSNFQLTHATELVQKSGSRAVSLGDIAQLQSLAAGKPFELAITFDIIDTAIMKEIVRQnnSAELKA 1189
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1139 AVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHsQEAKLAEAQQKAMLKGEAFPDIPMTLYEAIVRDYTG 1218
Cdd:TIGR02760 1190 AHNSLDKRSNPKALELLKNQNPLQHELMQNAAMPEIASDEQGL-QKHDLAKLAVNTEKPKKAQPDATVTLYREIVKDYLS 1268
                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1219 RTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWENNpDALALVDSVYHRIA 1298
Cdd:TIGR02760 1269 RTPEFRENTLIIAHTNNDRTGIYPFIREGLIKQKELSKQQVTVPRLRSVNISSPELKTMMPFEKG-AVLRLKKDAYLTIA 1347
                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1299 GISKDDGLITLEDAE-GNTRLISPREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSVWTVTAV-SGDSVTLSD 1376
Cdd:TIGR02760 1348 DIDREHGKLTVADIKtGSERDILPRQLDHTFTSLYSDSELPLAKGDKIRLRATDKNRGIKANEVYTVTQVvNGLSVQLSK 1427
                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1377 GQQTRVIRPGQERaEQHIDLAYAITAHGAQGASETFAIALegtEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWT-- 1454
Cdd:TIGR02760 1428 VKNSLSLKPIQAK-DKHWDYAYTRTADSAQGATYTFVIAL---IKGRLALTNYRSAYIDLTRASHHVELYTDNKEGTVks 1503
                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1455 ---------------------------------------------------DAINNAV---------------------- 1461
Cdd:TIGR02760 1504 wkqreanktsaveteedyrpkqstqfnnraqpheepkyqqkngplkiqsaaEIINEALpayteslaktllgepntqksrr 1583
                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1462 -----------------------------QKGTAHDVLEPKSD---REVMN----------------------------- 1480
Cdd:TIGR02760 1584 drytfgakgglkvsltgkyrglwhdfstgEKGTLIQLIEAKKGlsfKEALNqaasllgipqhyqlsinikapqlsntepq 1663
                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1481 --------AERLFSTARELRDVVAGRAVLRQAGLAGGDSPARFIAP-----GRKYPQPYVALPAFDRNGKSAGIWLNPLT 1547
Cdd:TIGR02760 1664 klnqlekrAKSLFQGSQELKGTLAEKYLKQHRGLASIDNDDIRFHPtvyssDKKNKHPALIAAARNEKGEITGIQITYLD 1743
                         1770      1780      1790      1800      1810      1820      1830      1840
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1548 TDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGE-SLLADNMQDGVRIARDNPDSGVVVRIAGegrpwnprtitggrvwg 1626
Cdd:TIGR02760 1744 KDDANKDKDMDNNKRVKGSISGQFVVINKGMQGDrSYIAEGIETGLSIALANPKATVVIAVGG----------------- 1806
                         1850      1860      1870      1880      1890      1900      1910      1920
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1627 dipDNSVQPGAGNGEPVTAEVLAQRQAEEAIrreTERRADEIVRKMAENK-----------PDLPDGKTEQAVRDIAGLE 1695
Cdd:TIGR02760 1807 ---KNNLSPIIPKFIPKNVVIVLDNDGEEAK---SQRAIEKIINKFKQDNisarivfpddwNDIGEEELQKQLMRAISSI 1880
                         1930      1940      1950      1960      1970      1980
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446909707  1696 RDRSAISEREAALPESVLREPQRVREAVREVARENLLQERLQQM-------ERDMVRDLQKEKTLGGD 1756
Cdd:TIGR02760 1881 EDKDIEIPKAIADFESVLKMPNSDIISIIDNARTEREKSDLEQIvanehksQQALERDLNKEFTPDKR 1948
relax_trwC TIGR02686
conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) ...
13-288 1.83e-138

conjugative relaxase domain, TrwC/TraI family; This domain is in the N-terminal (relaxase) region of TrwC, a relaxase-helicase that acts in plasmid R388 conjugation. The relaxase domain has DNA cleavage and strand transfer activities. Plasmid transfer protein TraI is also a member of this domain family. Members of this family on bacterial chromosomes typically are found near other genes typical of conjugative plasmids and appear to mark integrated plasmids. [Mobile and extrachromosomal element functions, Plasmid functions]


Pssm-ID: 274258 [Multi-domain]  Cd Length: 283  Bit Score: 430.34  E-value: 1.83e-138
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    13 AGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGKLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSV 92
Cdd:TIGR02686    1 AADYYTDGDNYYLKDSDAGRWLGKGAQELGLSGEVEKKQFEALLEGRLPDGTRLGRIEDRQSKHRPGFDLTFSAPKSVSI 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    93 MAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAVVANVTQH-NG 170
Cdd:TIGR02686   81 LALVGGDPRLIDAHDEAVKFTLEQLEKeAAAARVTQDGEIEFEKTGNLVIALFRHDTSRANDPQLHTHAVVANMTRRsDG 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   171 EWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIREAVGE 247
Cdd:TIGR02686  161 KWRSLSSDKKGKHGFIEEIYKNQIYLGLLYRAKLANELKELGYQTRVYGKHGNFEIDGVPeevIEAFSKRRQQIEEWVAE 240
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 446909707   248 D--ASLKSRDVAALDTRKSKQHVDPEVRMAEWMQTLKETGFDI 288
Cdd:TIGR02686  241 RgwSLAKSRDTAALDTRKKKTVHDREALREEWQQTAKELGFDP 283
MobF NF041492
MobF family relaxase;
1-281 4.84e-112

MobF family relaxase;


Pssm-ID: 469380 [Multi-domain]  Cd Length: 288  Bit Score: 357.38  E-value: 4.84e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    1 MMSIAQVRSAGSAGNYYTDKD--NYYVLG--SMGERWAGRGAEQLGL-QGSVDKDVFTRLLEGKLPDGADLSRMQDGSNK 75
Cdd:NF041492    1 MLSIARIGSAGGAARYYTEKDldNYYSEDggTPAGRWFGKGAEALGLsGGAVDGERFKALLDGRLPDGERLRRRRKGAGR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   76 HRPGYDLTFSAPKSVSVMAMLGGDKRLIDAHNQAVDFAVR-QVEALASTRVMTDGQSETVL--TGNLVMALFNHDTSRDQ 152
Cdd:NF041492   81 HRPGYDLTFSAPKSVSLLALVGGDKRLIEAHDEAVKEALEyLEERLAQTRVTVDGKGRTSLekTGNLVAALFRHDTSRAG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  153 EPQLHTHAVVANVTQH-NGEWKTLSSdkvgktgfiENVYANQIAFGRLYREKLKEQVEALGYETEVVgKHGMWEMPGVP- 230
Cdd:NF041492  161 DPQLHTHAVVMNMTQRpDGKWRSLDN---------EELYKNQKALGAIYQAELAEELQALGYEIRET-KNGQFEIAGVPr 230
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446909707  231 --VEAFSGRSQAIREAVGED----ASLKSRDVAALDTRKSKQ-HVDPEVRMAEWMQTL 281
Cdd:NF041492  231 eqIEAFSKRSQQIEEWLGENpatlASAALRQIAALDTRKAKEaDVDPEELEAEWREEA 288
TrwC pfam08751
TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative ...
10-283 1.37e-97

TrwC relaxase; Relaxases are DNA strand transferases which function during the conjugative cell to cell DNA transfer. TrwC binds to the origin of transfer (oriT) and melts the double helix.


Pssm-ID: 430190 [Multi-domain]  Cd Length: 279  Bit Score: 315.71  E-value: 1.37e-97
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    10 AGSAGNYYTDKDNYYVL-GSMGERWAGRGAEQLGLQGSVDKDVFTRLLEGKLPD-GADLSRMQDGSNKHRPGYDLTFSAP 87
Cdd:pfam08751    1 AGDAYAYYTRQDDYYTEgGEPPGRWLGKGAAALGLSGEVTEEQFEALLEGRHPDtGERLGRRRPRGRKHRAGFDLTFSAP 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707    88 KSVSVMAMLGGDKRLIDAHNQAVDFAVRQVEA-LASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHAVVANVT 166
Cdd:pfam08751   81 KSVSLLAAVGGDERIEAAHRAAVAEALAWLEKhAAQTRVGKDGGVEQVDTGGLVAAAFRHDTSRAGDPQLHTHVVVANVT 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   167 Q-HNGEWKTLSSDKvgktgfienVYANQIAFGRLYREKLKEQVEALGYETEVVGKHGMWEMPGVP---VEAFSGRSQAIR 242
Cdd:pfam08751  161 QrEDGKWRALDSRG---------LYKAQVAAGAVYRAELADELRRLGYEIEERGKRGVFEIAGVPeelIEAFSKRRAQIE 231
                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 446909707   243 EAVGE------DASLKSRDVAALDTRKSK-QHVDPEVRMAEWMQTLKE 283
Cdd:pfam08751  232 AELAElgathgRAPPAARQIAALETRPAKhEPRSLAELRARWREEAAE 279
TraI pfam07057
DNA helicase TraI; This family represents a conserved region approximately 130 residues long ...
1434-1557 3.24e-83

DNA helicase TraI; This family represents a conserved region approximately 130 residues long within the bacterial DNA helicase TraI (EC:3.6.1.-). TraI is a bifunctional protein that catalyzes the unwinding of duplex DNA as well as acts as a sequence-specific DNA trans-esterase, providing the site- and strand-specific nick required to initiate DNA transfer.


Pssm-ID: 429268 [Multi-domain]  Cd Length: 124  Bit Score: 268.02  E-value: 3.24e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1434 VALSRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKSDREVMNAERLFSTARELRDVVAGRAVLRQAGLAGGDSPA 1513
Cdd:pfam07057    1 VALSRMKQHVQVYTDNRQGWIKAINNAPQKGTAHDVLEPKNDREVMNADRLFSTARELRDVAAGRAVLRQAGLAQGDSPA 80
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 446909707  1514 RFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGF 1557
Cdd:pfam07057   81 RFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGRGLRGF 124
RecD COG0507
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ...
937-1468 1.86e-51

ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];


Pssm-ID: 440273 [Multi-domain]  Cd Length: 514  Bit Score: 190.96  E-value: 1.86e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  937 YEAEKSILRHILEGK------EAVTPLMERVPGELMEKLTSGQRAATRMILETSdRFTVVQGYAGVGKTTqfraVMSAVN 1010
Cdd:COG0507    87 LEAEQRLARRLRRLArpaldeADVEAALAALEPRAGITLSDEQREAVALALTTR-RVSVLTGGAGTGKTT----TLRALL 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1011 MLPESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFLH---DTQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYAL 1086
Cdd:COG0507   162 AALEALGLRVALAAPTGKAAKRLSeSTGIEARTIHRLLGlrpDSGRFRHNRDNPLTPADLLVVDEASMVDTRLMAALLEA 241
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1087 IAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELREAVYS-LINR-DVERALSglesvkpsqvp 1164
Cdd:COG0507   242 LPRAGARLILVGDPDQLPSVGAGAVLRDLIESGTVPVVELTEVYRQADDSRIIELAhAIREgDAPEALN----------- 310
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1165 rqegAWAPEHSVTEFSHSQEAKlaeaqqkamlkgeafpdipmtlyEAIVRDYTGRtPEAREQTLIVTHLNEDRRVLNSMI 1244
Cdd:COG0507   311 ----ARYADVVFVEAEDAEEAA-----------------------EAIVELYADR-PAGGEDIQVLAPTNAGVDALNQAI 362
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1245 HDAREKAGELGKEQvmvpvlntanIRDGELRrlstwennpdalalvdsvyhriagiskddglitledaegntrlisprea 1324
Cdd:COG0507   363 REALNPAGELEREL----------AEDGELE------------------------------------------------- 383
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1325 vaegvtlytpdtIRVgtGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLS---DGQQTRVIRPGQERaeqHIDLAYAIT 1401
Cdd:COG0507   384 ------------LYV--GDRVMFTRNDYDLGVFNGDIGTVLSIDEDEGRLTvrfDGREIVTYDPSELD---QLELAYAIT 446
                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446909707 1402 AHGAQGAseTF--AIALEGTEGNRklMAGFESAYVALSRMKQHVQVYTDNRQgWTDAINNAVQKGTAHD 1468
Cdd:COG0507   447 VHKSQGS--TFdrVILVLPSEHSP--LLSRELLYTALTRARELLTLVGDRDA-LARAVRRDTARATGLA 510
DEXSc_RecD-like cd17933
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ...
972-1130 1.53e-38

DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350691 [Multi-domain]  Cd Length: 155  Bit Score: 141.54  E-value: 1.53e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  972 GQRAATRMILetSDRFTVVQGYAGVGKTTQFRAVMSAVnmlpESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFLHDT 1050
Cdd:cd17933     1 EQKAAVRLVL--RNRVSVLTGGAGTGKTTTLKALLAAL----EAEGKRVVLAAPTGKAAKRLSeSTGIEASTIHRLLGIN 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1051 QLLQRS--GETPNFSNTLFLLDESSMVGNTDMARAYALIAAGGgRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKE 1128
Cdd:cd17933    75 PGGGGFyyNEENPLDADLLIVDEASMVDTRLMAALLSAIPAGA-RLILVGDPDQLPSVGAGNVLRDLIASKGVPTVELTE 153

                  ..
gi 446909707 1129 IV 1130
Cdd:cd17933   154 VF 155
AAA_30 pfam13604
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
969-1156 2.07e-35

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.


Pssm-ID: 433343 [Multi-domain]  Cd Length: 191  Bit Score: 133.84  E-value: 2.07e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   969 LTSGQRAATRMILETSDRFTVVQGYAGVGKTTqfraVMSAVNMLPESERPRVVGLGPTHRAVGEMR-SAGVDAQTLASFL 1047
Cdd:pfam13604    2 LNAEQAAAVRALLTSGDRVAVLVGPAGTGKTT----ALKALREAWEAAGYRVIGLAPTGRAAKVLGeELGIPADTIAKLL 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1048 HDTQLLQRSGetpnfSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFR-LQQTRsaADVVIM 1126
Cdd:pfam13604   78 HRLGGRAGLD-----PGTLLIVDEAGMVGTRQMARLLKLAEDAGARVILVGDPRQLPSVEAGGAFRdLLAAG--IGTAEL 150
                          170       180       190
                   ....*....|....*....|....*....|.
gi 446909707  1127 KEIVRQT-PELREAVYSLINRDVERALSGLE 1156
Cdd:pfam13604  151 TEIVRQRdPWQRAASLALRDGDPAEALDALA 181
TraI_2B pfam18340
DNA relaxase TraI 2B/2B-like domain; This is the 2B and 2B-like sub-domain found in TraI (EC:5. ...
633-712 1.36e-34

DNA relaxase TraI 2B/2B-like domain; This is the 2B and 2B-like sub-domain found in TraI (EC:5.99.1.2) a relaxase of F-family plasmids. It contains four domains; a trans-esterase domain that executes the nicking and covalent attachment of the T-strand to the relaxase, a vestigial helicase domain (carrying the 2B/2B-like sub-domain) that operates as an ssDNA-binding domain, an active 5' to 3' helicase domain, and a C-terminal domain that functions as a recruitment platform for relaxosome components. The 2B sub-domains in TraI are formed by residues 625-773 in the vestigial helicase domain and residues 1255-1397 in the active helicase domain. The 2B/2B-like sub-domain interacts with ssDNA where it contributes to the surface area where ssDNA bind. In other words the ssDNA-binding site is located in a groove between the 2B and 2B-like parts of the sub-domain. The sub-domain parts appear to act as clamps holding the ssDNA in place, resulting in the ssDNA being completely surrounded by protein. In previous studies, the 2B/2B-like sub-domain of the TraI vestigial helicase domain has been identified as translocation signal A (TSA) since it contains sequences essential for the recruitment of TraI to the T4S system. Thus, the 2B/2B-like sub-domain plays two major roles in relaxase function: (1) interacting with the DNA and possibly promoting high processivity and (2) mediating recruitment of the relaxosome to the T4S system.


Pssm-ID: 465718 [Multi-domain]  Cd Length: 79  Bit Score: 127.39  E-value: 1.36e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   633 ALSPVWLDSRSRYLRDMYRPGMVMEQWNPeTRSHDRYVIDRVTAQSNSLTLRDAQDETQVVRISSLDSSWSLFRPEKMPV 712
Cdd:pfam18340    1 TLTPVWLDSKNRRSRDSYREGMVLERWNG-ARKKQRFTIDRVTEKTNSLTLVDAKGETSTLKISEIDSHWRLFRSDKLEV 79
TraA_Ti TIGR02768
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a ...
934-1450 1.05e-22

Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, pfam03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer.


Pssm-ID: 274289 [Multi-domain]  Cd Length: 744  Bit Score: 105.66  E-value: 1.05e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   934 RASYEAEKSILRHILEGKEAVTPLMERVPGELMEKLTSGQRAATRMILEtSDRFTVVQGYAGVGKTTqfraVMSAVNMLP 1013
Cdd:TIGR02768  318 RLEAQMARSAEALSQSQGHGVSPPIVDAAIDQHYRLSEEQYEAVRHVTG-SGDIAVVVGRAGTGKST----MLKAAREAW 392
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1014 ESERPRVVGLGPTHRAVGEMR-SAGVDAQTLAS----FLHDTQLLQRSgetpnfsnTLFLLDESSMVGNTDMARAYALIA 1088
Cdd:TIGR02768  393 EAAGYRVIGAALSGKAAEGLQaESGIESRTLASleyaWANGRDLLSDK--------DVLVIDEAGMVGSRQMARVLKEAE 464
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1089 AGGGRAVASGDTDQLQAIAPGQPFRlqqtrsaadvvimkeivrqtpelreAVyslinrdVERalsgLESVKPSQVPRQEG 1168
Cdd:TIGR02768  465 EAGAKVVLVGDPEQLQPIEAGAAFR-------------------------AI-------AER----IGYAELETIRRQRE 508
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1169 AWAPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDIPMtlyEAIVRDYTGRTPEAREQ--TLIVTHLNEDRRVLNSMIHD 1246
Cdd:TIGR02768  509 AWARQASLELARGDVEKALAAYRDHGHITIHDTREEAI---EQVVADWKQDLREANPAgsQIMLAHTRKDVRALNEAARE 585
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1247 AREKAGELGKEqvmvpvlntanirdgelrrlstwennpdalalvdsvyhriagiskddglITLEDAEGNTRLispreava 1326
Cdd:TIGR02768  586 ALIERGELGES-------------------------------------------------ILFQTARGERKF-------- 608
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  1327 egvtlytpdtirvGTGDRMRFTKSDRERGYVANSVWTVTAVSGD--SVTLSDGQQTRVirpgQERAEQHIDLAYAITAHG 1404
Cdd:TIGR02768  609 -------------AAGDRIVFLENNRDLGVKNGMLGTVEEIEDGrlVVQLDSGELVII----PQAEYDALDHGYATTIHK 671
                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 446909707  1405 AQGASETFAIALEGTEGNRKLmagfesAYVALSRMKQHVQVYTDNR 1450
Cdd:TIGR02768  672 SQGVTVDRAFVLASKSMDRHL------AYVAMTRHRESVQLYAGKE 711
ssDNA_TraI_N pfam18272
single-stranded DNA binding TraI N-terminal subdomain; This is a subdomain found in TraI ...
575-626 1.18e-18

single-stranded DNA binding TraI N-terminal subdomain; This is a subdomain found in TraI present in E. coli. Tra1 is a conjugative relaxase that forms part of the Type IV secretion system. This subdomain, referred to as 2A, is located in N-terminal region of the translocation signal (TSA) domain. TSA is known to reside in a larger ssDNA-binding domain.


Pssm-ID: 408086 [Multi-domain]  Cd Length: 53  Bit Score: 81.00  E-value: 1.18e-18
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 446909707   575 DRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVLGR 626
Cdd:pfam18272    1 DKAQRYGRLAKEFVQAVREGEESVAQVSGPREQAVLAGMIRDELKEEGVLGR 52
PRK13826 PRK13826
Dtr system oriT relaxase; Provisional
967-1450 4.23e-11

Dtr system oriT relaxase; Provisional


Pssm-ID: 237524 [Multi-domain]  Cd Length: 1102  Bit Score: 68.27  E-value: 4.23e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  967 EKLTSGQRAATRMILETSdRFTVVQGYAGVGKTTQFRAVMSAVnmlpESERPRVVGLGPTHRAV-GEMRSAGVDAQTLAS 1045
Cdd:PRK13826  380 ARLSDEQKTAIEHVAGPA-RIAAVVGRAGAGKTTMMKAAREAW----EAAGYRVVGGALAGKAAeGLEKEAGIQSRTLSS 454
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1046 FlhdtQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFrlqqtRSAADVVI 1125
Cdd:PRK13826  455 W----ELRWNQGRDQLDNKTVFVLDEAGMVASRQMALFVEAVTRAGAKLVLVGDPEQLQPIEAGAAF-----RAIADRIG 525
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1126 MKE---IVRQTPE-LREAVYSLINRDVERALSglesvkpsqvprqegawapehsvtefSHSQEAKLAEAQqkamLKGEAF 1201
Cdd:PRK13826  526 YAEletIYRQREQwMRDASLDLARGNVGKALD--------------------------AYRANGRVIGSR----LKAEAV 575
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1202 PdipmTLYEAIVRDYtgrtpEAREQTLIVTHLNEDRRVLNSMihdAREKagelgkeqvmvpvlntanirdgelrrlstwe 1281
Cdd:PRK13826  576 E----SLIADWNRDY-----DPTKTTLILAHLRRDVRMLNEM---ARAK------------------------------- 612
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1282 nnpdalaLVDsvyhriagiskddglitledaegntrlispREAVAEGVTLYTPDTIR-VGTGDRMRFTKSDRERGyVANS 1360
Cdd:PRK13826  613 -------LVE------------------------------RGIVGEGHAFRTADGERrFAAGDQIVFLKNEGSLG-VKNG 654
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1361 VW--TVTAVSGDSV-TLSDGQQTRVIRPGQeRAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKLmagfesAYVALS 1437
Cdd:PRK13826  655 MIgkVVEAAPNRIVaEIGEGEHRRQVTVEQ-RFYNNLDHGYATTIHKSQGATVDRVKVLASLSLDRHL------TYVAMT 727
                         490
                  ....*....|...
gi 446909707 1438 RMKQHVQVYTDNR 1450
Cdd:PRK13826  728 RHREDLQLYYGRR 740
AAA_19 pfam13245
AAA domain;
973-1103 8.29e-10

AAA domain;


Pssm-ID: 433059 [Multi-domain]  Cd Length: 136  Bit Score: 58.77  E-value: 8.29e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707   973 QRAATRMILEtsDRFTVVQGYAGVGKTTQFRA-VMSAVNMLPESERprVVGLGPTHRAVGEMRSA-GVDAQTLASFLHDT 1050
Cdd:pfam13245    1 QREAVRTALP--SKVVLLTGGPGTGKTTTIRHiVALLVALGGVSFP--ILLAAPTGRAAKRLSERtGLPASTIHRLLGFD 76
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 446909707  1051 QL----LQRSGETPnFSNTLFLLDESSMVgntDMARAYALIAA--GGGRAVASGDTDQL 1103
Cdd:pfam13245   77 DLeaggFLRDEEEP-LDGDLLIVDEFSMV---DLPLAYRLLKAlpDGAQLLLVGDPDQL 131
SF1_C_RecD cd18809
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ...
1396-1447 6.36e-08

C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350196 [Multi-domain]  Cd Length: 80  Bit Score: 51.41  E-value: 6.36e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 446909707 1396 LAYAITAHGAQGASETFAIALEGTEGNrklMAGFESAYVALSRMKQHVQVYT 1447
Cdd:cd18809    32 QAYAMTIHKSQGSEFDRVIVVLPTSHP---MLSRGLLYTALTRARKLLTLVG 80
PRK13889 PRK13889
conjugal transfer relaxase TraA; Provisional
969-1753 1.60e-06

conjugal transfer relaxase TraA; Provisional


Pssm-ID: 237546 [Multi-domain]  Cd Length: 988  Bit Score: 53.16  E-value: 1.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707  969 LTSGQRAATRMILETSDrFTVVQGYAGVGKTTQFRAVMSAVnmlpESERPRVVGLGPTHRAVGEMRS-AGVDAQTLASFL 1047
Cdd:PRK13889  347 LSGEQADALAHVTDGRD-LGVVVGYAGTGKSAMLGVAREAW----EAAGYEVRGAALSGIAAENLEGgSGIASRTIASLE 421
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1048 HD----TQLLQrsgetpnfSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAAdv 1123
Cdd:PRK13889  422 HGwgqgRDLLT--------SRDVLVIDEAGMVGTRQLERVLSHAADAGAKVVLVGDPQQLQAIEAGAAFRSIHERHGG-- 491
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1124 VIMKEIVRQTPE-LREAVYSLINRDVERALsglesvkpsqvprqegawapeHSVTEFSHSQEAKLAEAQQKAmlkgeafp 1202
Cdd:PRK13889  492 AEIGEVRRQREDwQRDATRDLATGRTGEAL---------------------DAYEAHGMVHAAATREQARAD-------- 542
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1203 dipmtLYEAIVRDytgRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGkeqvmvpvlntanirdgelrrlstwen 1282
Cdd:PRK13889  543 -----LIDRWDRD---RQAAPDRSRIILTHTNDEVRALNEAARERMRAAGDLG--------------------------- 587
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1283 npdalalvdsvyhriagiskDDGLITLEDAEGNtrlispreavaegvtlytpdtirVGTGDRMRFTKSDRERGYVANSVW 1362
Cdd:PRK13889  588 --------------------DDVRVTVERGERS-----------------------FASGDRVMFLQNERGLGVKNGTLG 624
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1363 TVTAVSGDSVT--LSDGQQTRVirpgQERAEQHIDLAYAITAHGAQGAS--ETFAIALEGTEGNrklmagfeSAYVALSR 1438
Cdd:PRK13889  625 TIEQVSAQSMSvrLDDGRSVAF----DLKDYDRIDHGYAATIHKAQGMTvdRTHVLATPGMDAH--------SSYVALSR 692
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1439 MKQHVQVYT-----DNRQGWTDAINNAVQKGTAHDVlePKSDREVMNAERLFSTARELRDVVAGRAV-LRQAGLAGGDSP 1512
Cdd:PRK13889  693 HRDGVDLHYgrddfADRDRLVRTLSRDRAKDMASDY--ERADPAQSYAERRGITFRERVAEIVRKIVpEKLRGMFDGLRL 770
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1513 ARFIAPGRkyPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGV 1592
Cdd:PRK13889  771 PDPVPGPE--AGRRPERESAAATTDAPARTVAADPEAALRQARTRALVRHARAVDAIFRMQEQGGPVLPHQVKELQEARK 848
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1593 RIARDNPDSGVVVRIAGEGRPWNPRTITGGRVwgdipdnsvqpgagngepvtAEVLAQRQAEEAIRRETERRADEIVRKM 1672
Cdd:PRK13889  849 AFEEVRPYGSHDAEAAYKKNPELAAEAASGRP--------------------ARAIRALQLETELRTDPARRADRFVERW 908
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446909707 1673 AenKPDLPDGKTEQAvRDIAGLERDRSAISEreaaLPESVLREPQrvreavrevaRENLLQERLQQM--ERDMVRDLQKE 1750
Cdd:PRK13889  909 Q--KLDRASQRQYQA-GDMSGYKATRAAMGD----MAKSLERDPQ----------LESLLAGRKRELgiGFESGRRLGRE 971

                  ...
gi 446909707 1751 KTL 1753
Cdd:PRK13889  972 LAF 974
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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