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Conserved domains on  [gi|446971924|ref|WP_001049180|]
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MULTISPECIES: ATP-binding protein [Enterobacterales]

Protein Classification

ATP-binding protein( domain architecture ID 10598562)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain similar to Nostoc sp. Tn7 transposition protein TnsC

CATH:  3.40.50.300
Gene Ontology:  GO:0005524|GO:0016887
PubMed:  15037234|18208389|17897320|18466635|16072036|11916378|15037233
SCOP:  2000039

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AAA_22 pfam13401
AAA domain;
130-275 3.07e-14

AAA domain;


:

Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 69.29  E-value: 3.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924  130 ITIVGMSGSGKTTMIEQVMDHFPQiiEHSSYkgvfpgfskqivwVKINCPYNSSVRDLCEEILQKLDdaigiERTTPEIR 209
Cdd:pfam13401   8 LVLTGESGTGKTTLLRRLLEQLPE--VRDSV-------------VFVDLPSGTSPKDLLRALLRALG-----LPLSGRLS 67

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446971924  210 NGALARQIAQRIKSSFL-GILVIDEMQRLKFsrtggesKLIDFLHEIVD--SMGVSMVFCGNHPFDETL 275
Cdd:pfam13401  68 KEELLAALQQLLLALAVaVVLIIDEAQHLSL-------EALEELRDLLNlsSKLLQLILVGTPELRELL 129
 
Name Accession Description Interval E-value
AAA_22 pfam13401
AAA domain;
130-275 3.07e-14

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 69.29  E-value: 3.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924  130 ITIVGMSGSGKTTMIEQVMDHFPQiiEHSSYkgvfpgfskqivwVKINCPYNSSVRDLCEEILQKLDdaigiERTTPEIR 209
Cdd:pfam13401   8 LVLTGESGTGKTTLLRRLLEQLPE--VRDSV-------------VFVDLPSGTSPKDLLRALLRALG-----LPLSGRLS 67

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446971924  210 NGALARQIAQRIKSSFL-GILVIDEMQRLKFsrtggesKLIDFLHEIVD--SMGVSMVFCGNHPFDETL 275
Cdd:pfam13401  68 KEELLAALQQLLLALAVaVVLIIDEAQHLSL-------EALEELRDLLNlsSKLLQLILVGTPELRELL 129
COG2842 COG2842
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ...
 132-367 8.49e-12

Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];


Pssm-ID: 442090 [Multi-domain]  Cd Length: 254  Bit Score: 65.36  E-value: 8.49e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924 132 IVGMSGSGKTTMIEQVMDHFPQiiehssykgvfpgfskqiVWVkINCPYNSSVRDLCEEILqkldDAIGIerTTPEIRNG 211
Cdd:COG2842   55 VYGESGVGKTTAAREYANRNPN------------------VIY-VTASPSWTSKELLEELA----EELGI--PAPPGTIA 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924 212 ALARQIAQRIKSSFlGILVIDEMQRLKFsrtggesKLIDFLHEIVDSMGVSMVFCGNHPFDETLTKKMRIARRAESggYM 291
Cdd:COG2842  110 DLRDRILERLAGTG-RLLIIDEADHLKP-------KALEELRDIHDETGVGVVLIGMERLPAKLKRYEQLYSRIGF--WV 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446971924 292 KIKNVRYDsqDWQSFIhylwpLQWTNVETPlndELNEKLFILSKGNIGLAQMIYRGAQLKVIGSGNEIITGAVLSA 367
Cdd:COG2842  180 EFKPLSLE--DVRALA-----EAWGELTDP---DLLELLHRITRGNLRRLDRTLRLAARAAKRNGLTKITLDHVRA 245
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 128-284 1.16e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.28  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924   128 ETITIVGMSGSGKTTMIEQVMDHFPQiiehsSYKGVfpgfskqivwVKINCPYNssvrdlcEEILQKLDDAIGIERTTPE 207
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGP-----PGGGV----------IYIDGEDI-------LEEVLDQLLLIIVGGKKAS 60

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446971924   208 IRNGALARQIAQRIKSSFLGILVIDEMQRL--KFSRTGGESKLIDFLHEIVDSMGVSMVFCGNHPFDETLTKKMRIARR 284
Cdd:smart00382  61 GSGELRLRLALALARKLKPDVLILDEITSLldAEQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRRRFD 139
 
Name Accession Description Interval E-value
AAA_22 pfam13401
AAA domain;
130-275 3.07e-14

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 69.29  E-value: 3.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924  130 ITIVGMSGSGKTTMIEQVMDHFPQiiEHSSYkgvfpgfskqivwVKINCPYNSSVRDLCEEILQKLDdaigiERTTPEIR 209
Cdd:pfam13401   8 LVLTGESGTGKTTLLRRLLEQLPE--VRDSV-------------VFVDLPSGTSPKDLLRALLRALG-----LPLSGRLS 67

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446971924  210 NGALARQIAQRIKSSFL-GILVIDEMQRLKFsrtggesKLIDFLHEIVD--SMGVSMVFCGNHPFDETL 275
Cdd:pfam13401  68 KEELLAALQQLLLALAVaVVLIIDEAQHLSL-------EALEELRDLLNlsSKLLQLILVGTPELRELL 129
COG2842 COG2842
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ...
 132-367 8.49e-12

Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];


Pssm-ID: 442090 [Multi-domain]  Cd Length: 254  Bit Score: 65.36  E-value: 8.49e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924 132 IVGMSGSGKTTMIEQVMDHFPQiiehssykgvfpgfskqiVWVkINCPYNSSVRDLCEEILqkldDAIGIerTTPEIRNG 211
Cdd:COG2842   55 VYGESGVGKTTAAREYANRNPN------------------VIY-VTASPSWTSKELLEELA----EELGI--PAPPGTIA 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924 212 ALARQIAQRIKSSFlGILVIDEMQRLKFsrtggesKLIDFLHEIVDSMGVSMVFCGNHPFDETLTKKMRIARRAESggYM 291
Cdd:COG2842  110 DLRDRILERLAGTG-RLLIIDEADHLKP-------KALEELRDIHDETGVGVVLIGMERLPAKLKRYEQLYSRIGF--WV 179

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446971924 292 KIKNVRYDsqDWQSFIhylwpLQWTNVETPlndELNEKLFILSKGNIGLAQMIYRGAQLKVIGSGNEIITGAVLSA 367
Cdd:COG2842  180 EFKPLSLE--DVRALA-----EAWGELTDP---DLLELLHRITRGNLRRLDRTLRLAARAAKRNGLTKITLDHVRA 245
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
 105-237 4.54e-05

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 45.16  E-value: 4.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924 105 YLHYYG-NERP-DIEPESGYF---KSQAET--------------ITIVGMSGSGKTTMIEQVMDHFPQiiehssykgvfp 165
Cdd:COG3267    2 YLEFFGlKEKPfSLTPDPRFLflsPSHREAlarleyalaqgggfVVLTGEVGTGKTTLLRRLLERLPD------------ 69

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446971924 166 gfskQIVWVKINCPYNSSvrdlcEEILQKLDDAIGIErtTPEIRNGALARQIAQRIKSSFLG----ILVIDEMQRL 237
Cdd:COG3267   70 ----DVKVAYIPNPQLSP-----AELLRAIADELGLE--PKGASKADLLRQLQEFLLELAAAgrrvVLIIDEAQNL 134
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
 123-264 7.22e-05

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 43.26  E-value: 7.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924  123 FKSQAETITIVGMSGSGKTTMIEQVMDHFPQIIEHSSYkGVFPGFSKQIVWVKInCPYNSSVRDLCEEILQKLDDAIGIE 202
Cdd:pfam13191  20 RSGRPPSVLLTGEAGTGKTTLLRELLRALERDGGYFLR-GKCDENLPYSPLLEA-LTREGLLRQLLDELESSLLEAWRAA 97

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446971924  203 RTTPEIRNGALARQIAQRIKSSFLG------------ILVIDEMQRLKFSrtggESKLIDFLHEIVDSMGVSMV 264
Cdd:pfam13191  98 LLEALAPVPELPGDLAERLLDLLLRlldllargerplVLVLDDLQWADEA----SLQLLAALLRLLESLPLLVV 167
NB-ARC pfam00931
NB-ARC domain;
130-195 7.22e-04

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 41.21  E-value: 7.22e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446971924  130 ITIVGMSGSGKTTMIEQVMDHFPQIIEHssykgvFPGfskqIVWVKINCPYnsSVRDLCEEILQKL 195
Cdd:pfam00931  21 VGIHGMGGVGKTTLAAQIFNDFDEVEGH------FDS----VAWVVVSKTF--TISTLQQTILQNL 74
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 128-284 1.16e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.28  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924   128 ETITIVGMSGSGKTTMIEQVMDHFPQiiehsSYKGVfpgfskqivwVKINCPYNssvrdlcEEILQKLDDAIGIERTTPE 207
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGP-----PGGGV----------IYIDGEDI-------LEEVLDQLLLIIVGGKKAS 60

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446971924   208 IRNGALARQIAQRIKSSFLGILVIDEMQRL--KFSRTGGESKLIDFLHEIVDSMGVSMVFCGNHPFDETLTKKMRIARR 284
Cdd:smart00382  61 GSGELRLRLALALARKLKPDVLILDEITSLldAEQEALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRRRFD 139
TniB pfam05621
Bacterial TniB protein; This family consists of several bacterial TniB NTP-binding proteins. ...
 132-237 1.98e-03

Bacterial TniB protein; This family consists of several bacterial TniB NTP-binding proteins. TniB is a probable ATP-binding protein which is involved in Tn5053 mercury resistance transposition. This entry represents a P-loop domain.


Pssm-ID: 428547  Cd Length: 189  Bit Score: 39.49  E-value: 1.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924  132 IVGMSGSGKTTMIEQ-VMDHFPQiieHSSYKGVFPgfskqiVWVkINCPYNSSVRDLCEEILQKLDDAIGIERTTPEIRN 210
Cdd:pfam05621  40 LVGDSNNGKTMIVERfARLHPPT---DDEDAEIVP------VVV-VQMPPKPDEKRLYVAILEALGAPFRPRDRLSKLEQ 109

                          90       100
                  ....*....|....*....|....*....
gi 446971924  211 GALA--RQIAQRikssflgILVIDEMQRL 237
Cdd:pfam05621 110 QVLRllRAVGVR-------MLIIDEFHNL 131
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
125-268 3.10e-03

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 39.83  E-value: 3.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924 125 SQAETITIVGMSGSGKTTMIEQVMDhfpQIIEHSSYKGVfpgfskQIVWVKINCPYNSSVRDLCEEILQKLDDAIGIERT 204
Cdd:COG1474   49 ERPSNVLIYGPTGTGKTAVAKYVLE---ELEEEAEERGV------DVRVVYVNCRQASTRYRVLSRILEELGSGEDIPST 119

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446971924 205 ---TPEIRNgalarQIAQRIKSSFLGILVI-DEMQRLkFSRTGGEskLIDFL---HEIVDSMGVSMVFCGN 268
Cdd:COG1474  120 glsTDELFD-----RLYEALDERDGVLVVVlDEIDYL-VDDEGDD--LLYQLlraNEELEGARVGVIGISN 182
COG1672 COG1672
Predicted ATPase, archaeal AAA+ ATPase superfamily [General function prediction only];
119-267 3.26e-03

Predicted ATPase, archaeal AAA+ ATPase superfamily [General function prediction only];


Pssm-ID: 441278 [Multi-domain]  Cd Length: 324  Bit Score: 39.51  E-value: 3.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924 119 ESGYFKSQAETITIVGMSGSGKTTMIEQvmdhfpqiiehssykgvfpgFSKQIVWVKINCPYNSSvRDLCEEILQKLDDA 198
Cdd:COG1672   13 EKLYESDGGELVVVYGRRRVGKTSLIKE--------------------FLKEKPAIYFDAREESE-RESLRDFSEALAEA 71

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446971924 199 IGIERTTPEIRN-GALARQIAQRIKSSFLgILVIDEMQRLKFSRTGGESKLIDFLHEIVDSMGVSMVFCG 267
Cdd:COG1672   72 LGDPLSKKEFESwEEAFEYLAELAEGKRL-VIVIDEFQYLVKLDPSLLSILQYLWDELLSDSNVSLILCG 140
MobB COG1763
Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme transport and metabolism]; ...
 130-147 6.50e-03

Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme transport and metabolism]; Molybdopterin-guanine dinucleotide biosynthesis protein is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 441369 [Multi-domain]  Cd Length: 162  Bit Score: 37.47  E-value: 6.50e-03
                         10
                 ....*....|....*...
gi 446971924 130 ITIVGMSGSGKTTMIEQV 147
Cdd:COG1763    4 LGIVGYSGSGKTTLLEKL 21
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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