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Conserved domains on  [gi|446982636|ref|WP_001059892|]
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MULTISPECIES: GNAT family N-acetyltransferase [Enterobacteriaceae]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10793314)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate, similar to Escherichia coli uncharacterized N-acetyltransferase YafP

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK09831 PRK09831
GNAT family N-acetyltransferase;
4-150 6.88e-107

GNAT family N-acetyltransferase;


:

Pssm-ID: 182099  Cd Length: 147  Bit Score: 300.72  E-value: 6.88e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   4 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQISAWAQIDESRWKEKLAKSQVWVAIINAQPVGFISRIEHYIDMLFV 83
Cdd:PRK09831   1 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFITCIEHYIDMLFV 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446982636  84 DPEYTRRGVASALLKPLIKSESELTVDASITAKPFFERYGFQTVKQQRVECRGAWFTNFYMRYKPQH 150
Cdd:PRK09831  81 DPEYTRRGVASALLKPLIKSESELTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYKPQH 147
 
Name Accession Description Interval E-value
PRK09831 PRK09831
GNAT family N-acetyltransferase;
4-150 6.88e-107

GNAT family N-acetyltransferase;


Pssm-ID: 182099  Cd Length: 147  Bit Score: 300.72  E-value: 6.88e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   4 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQISAWAQIDESRWKEKLAKSQVWVAIINAQPVGFISRIEHYIDMLFV 83
Cdd:PRK09831   1 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFITCIEHYIDMLFV 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446982636  84 DPEYTRRGVASALLKPLIKSESELTVDASITAKPFFERYGFQTVKQQRVECRGAWFTNFYMRYKPQH 150
Cdd:PRK09831  81 DPEYTRRGVASALLKPLIKSESELTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYKPQH 147
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 33-147 1.65e-23

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 88.87  E-value: 1.65e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   33 YSPQQISAWA-QIDESRWKEKLAKS--QVWVAIINAQPVGFIS-RIEHYIDMLFVDPEYTRRGVASALLKPLIK------ 102
Cdd:pfam13673   5 YSEEGIETFYeFISPEALRERIDQGeyFFFVAFEGGQIVGVIAlRDRGHISLLFVDPDYQGQGIGKALLEAVEDyaekdg 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 446982636  103 -SESELTVDASITAKPFFERYGFQTVKQQRVEcRGAWFTNfyMRYK 147
Cdd:pfam13673  85 iKLSELTVNASPYAVPFYEKLGFRATGPEQEF-NGIRFVP--MEKE 127
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
6-134 7.11e-16

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 69.73  E-value: 7.11e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   6 IRNYQPGDFQQLCAIFIRAvtmtasqhyspqqisaWAQIDESRWKEKLAKS----QVWVAIINAQPVGFI--SRIEH--- 76
Cdd:COG3153    1 IRPATPEDAEAIAALLRAA----------------FGPGREAELVDRLREDpaagLSLVAEDDGEIVGHValSPVDIdge 64

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446982636  77 ----YIDMLFVDPEYTRRGVASALLKPLIKS-----ESELTVDASITAKPFFERYGFQTVKQQRVEC 134
Cdd:COG3153   65 gpalLLGPLAVDPEYRGQGIGRALMRAALEAarergARAVVLLGDPSLLPFYERFGFRPAGELGLTL 131
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 58-102 3.10e-08

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 47.66  E-value: 3.10e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446982636  58 VWVAIINAQPVGFIS-------RIEHYIDMLFVDPEYTRRGVASALLKPLIK 102
Cdd:cd04301    1 FLVAEDDGEIVGFASlspdgsgGDTAYIGDLAVLPEYRGKGIGSALLEAAEE 52
Spm_actase_Thplmales NF041158
spermidine N(1)-acetyltransferase;
4-106 2.07e-03

spermidine N(1)-acetyltransferase;


Pssm-ID: 469070  Cd Length: 115  Bit Score: 36.06  E-value: 2.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   4 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQISAWaqIDESRWKEKL----AKSQVWVAII------NAQPVGFI-- 71
Cdd:NF041158   2 ITIRKLSAEDVDALIEVARESWKWTYRDIYSNEFIESW--ISEKYSKEKLlneiIRSQSNLDIIflgafvNSALIGFIel 79

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 446982636  72 ----SRIEhyIDMLFVDPEYTRRGVASALLkplikSESE 106
Cdd:NF041158  80 kiiaDKAE--LLRLYLKPEYTHRGIGKLLL-----SEAE 111
 
Name Accession Description Interval E-value
PRK09831 PRK09831
GNAT family N-acetyltransferase;
4-150 6.88e-107

GNAT family N-acetyltransferase;


Pssm-ID: 182099  Cd Length: 147  Bit Score: 300.72  E-value: 6.88e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   4 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQISAWAQIDESRWKEKLAKSQVWVAIINAQPVGFISRIEHYIDMLFV 83
Cdd:PRK09831   1 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFITCIEHYIDMLFV 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446982636  84 DPEYTRRGVASALLKPLIKSESELTVDASITAKPFFERYGFQTVKQQRVECRGAWFTNFYMRYKPQH 150
Cdd:PRK09831  81 DPEYTRRGVASALLKPLIKSESELTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYKPQH 147
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 33-147 1.65e-23

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 88.87  E-value: 1.65e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   33 YSPQQISAWA-QIDESRWKEKLAKS--QVWVAIINAQPVGFIS-RIEHYIDMLFVDPEYTRRGVASALLKPLIK------ 102
Cdd:pfam13673   5 YSEEGIETFYeFISPEALRERIDQGeyFFFVAFEGGQIVGVIAlRDRGHISLLFVDPDYQGQGIGKALLEAVEDyaekdg 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 446982636  103 -SESELTVDASITAKPFFERYGFQTVKQQRVEcRGAWFTNfyMRYK 147
Cdd:pfam13673  85 iKLSELTVNASPYAVPFYEKLGFRATGPEQEF-NGIRFVP--MEKE 127
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
6-134 7.11e-16

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 69.73  E-value: 7.11e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   6 IRNYQPGDFQQLCAIFIRAvtmtasqhyspqqisaWAQIDESRWKEKLAKS----QVWVAIINAQPVGFI--SRIEH--- 76
Cdd:COG3153    1 IRPATPEDAEAIAALLRAA----------------FGPGREAELVDRLREDpaagLSLVAEDDGEIVGHValSPVDIdge 64

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446982636  77 ----YIDMLFVDPEYTRRGVASALLKPLIKS-----ESELTVDASITAKPFFERYGFQTVKQQRVEC 134
Cdd:COG3153   65 gpalLLGPLAVDPEYRGQGIGRALMRAALEAarergARAVVLLGDPSLLPFYERFGFRPAGELGLTL 131
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
3-146 9.23e-15

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 67.33  E-value: 9.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   3 NIQIRNYQPGDFQQLCAIfIRAVTMTASQHYSPQQISAwaQIDESRWKEKLAKSQ-VWVAIINAQPVGFIS--------- 72
Cdd:COG1247    1 EMTIRPATPEDAPAIAAI-YNEAIAEGTATFETEPPSE--EEREAWFAAILAPGRpVLVAEEDGEVVGFASlgpfrprpa 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636  73 RIEHYIDMLFVDPEYTRRGVASALLKPLIK-SES------ELTVDAS-ITAKPFFERYGFQTVKQQRVECR--GAWFTNF 142
Cdd:COG1247   78 YRGTAEESIYVDPDARGRGIGRALLEALIErARArgyrrlVAVVLADnEASIALYEKLGFEEVGTLPEVGFkfGRWLDLV 157


                 ....
gi 446982636 143 YMRY 146
Cdd:COG1247  158 LMQK 161
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 4-138 5.29e-13

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 61.93  E-value: 5.29e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   4 IQIRNYQPGDFQQLCAIfiravtmtasqhyspqqISAWAQIDESRwkeklaksQVWVAIINAQPVGFISRIEH-----YI 78
Cdd:COG1246    1 MTIRPATPDDVPAILEL-----------------IRPYALEEEIG--------EFWVAEEDGEIVGCAALHPLdedlaEL 55

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446982636  79 DMLFVDPEYTRRGVASALLKPLIKSE-----SELTVDASITAKPFFERYGFQTVKQQRVECRGAW 138
Cdd:COG1246   56 RSLAVHPDYRGRGIGRRLLEALLAEArelglKRLFLLTTSAAIHFYEKLGFEEIDKEDLPYAKVW 120
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 55-125 7.89e-13

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 60.16  E-value: 7.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   55 KSQVWVAIINAQPVGFIS------RIEHYIDMLFVDPEYTRRGVASALLKPLIKSESE-----LTVDASITAKPFFERYG 123
Cdd:pfam13508   2 GGRFFVAEDDGKIVGFAAllplddEGALAELRLAVHPEYRGQGIGRALLEAAEAAAKEggiklLELETTNRAAAFYEKLG 81


                  ..
gi 446982636  124 FQ 125
Cdd:pfam13508  82 FE 83
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 53-148 1.55e-10

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 55.44  E-value: 1.55e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636  53 LAKSQVWVAIINAQPVGF--ISRIEH---YIDMLFVDPEYTRRGVASALLKPLIK-------SESELTV-DASITAKPFF 119
Cdd:COG0454   31 LAGAEFIAVDDKGEPIGFagLRRLDDkvlELKRLYVLPEYRGKGIGKALLEALLEwarergcTALELDTlDGNPAAIRFY 110

                         90       100
                 ....*....|....*....|....*....
gi 446982636 120 ERYGFQTVKQQRVecrgAWFTNFYMRYKP 148
Cdd:COG0454  111 ERLGFKEIERYVA----YVGGEFEKELSL 135
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 45-124 3.92e-10

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 54.06  E-value: 3.92e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   45 DESRWKEKLAKSQVWVAIINAQPVGFIS-------RIEHYIDMLFVDPEYTRRGVASALLKPLIK-------SESELTVD 110
Cdd:pfam00583  22 DLLEDWDEDASEGFFVAEEDGELVGFASlsiiddePPVGEIEGLAVAPEYRGKGIGTALLQALLEwarergcERIFLEVA 101

                          90
                  ....*....|....*
gi 446982636  111 AS-ITAKPFFERYGF 124
Cdd:pfam00583 102 ADnLAAIALYEKLGF 116
PRK10514 PRK10514
putative acetyltransferase; Provisional
 4-125 1.48e-09

putative acetyltransferase; Provisional


Pssm-ID: 182510 [Multi-domain]  Cd Length: 145  Bit Score: 53.08  E-value: 1.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   4 IQIRNYQPGDFQQLCAIFIRAVTmtASQHY-SPQQISAwaqIDESRwKEKLAKSQVWVAIINA-QPVGFISRIEHYIDML 81
Cdd:PRK10514   2 ISIRRSRHEEGERLVAIWRRSVD--ATHDFlSAEDRAE---IEELV-RSFLPEAPLWVAVDERdQPVGFMLLSGGHMEAL 75

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 446982636  82 FVDPEYTRRGVASALLKPLIKSESELTVDA---SITAKPFFERYGFQ 125
Cdd:PRK10514  76 FVDPDVRGCGVGRMLVEHALSLHPELTTDVneqNEQAVGFYKKMGFK 122
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 75-131 5.29e-09

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 50.42  E-value: 5.29e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446982636  75 EHYIDMLFVDPEYTRRGVASALLKPLIK-------SESELTVDAS-ITAKPFFERYGFQTVKQQR 131
Cdd:COG0456   13 EAEIEDLAVDPEYRGRGIGRALLEAALErarergaRRLRLEVREDnEAAIALYEKLGFEEVGERP 77
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 58-102 3.10e-08

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 47.66  E-value: 3.10e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446982636  58 VWVAIINAQPVGFIS-------RIEHYIDMLFVDPEYTRRGVASALLKPLIK 102
Cdd:cd04301    1 FLVAEDDGEIVGFASlspdgsgGDTAYIGDLAVLPEYRGKGIGSALLEAAEE 52
PRK10562 PRK10562
putative acetyltransferase; Provisional
 6-97 1.99e-06

putative acetyltransferase; Provisional


Pssm-ID: 236715 [Multi-domain]  Cd Length: 145  Bit Score: 44.67  E-value: 1.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   6 IRNYQPGDFQQLCAIFIravtmtasqhysPQQISAWAQIDESRWKEK--------LAKSQVWVAIINAQPVGFISRIE-H 76
Cdd:PRK10562   2 IREYQPSDLPAILQLWL------------ESTIWAHPFIKEQYWRESaplvrdvyLPAAQTWVWEEDGKLLGFVSVLEgR 69

                         90       100
                 ....*....|....*....|.
gi 446982636  77 YIDMLFVDPEYTRRGVASALL 97
Cdd:PRK10562  70 FVGALFVAPKAVRRGIGKALM 90
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
35-127 3.17e-06

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 44.02  E-value: 3.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636  35 PQQISAWAQIDEsrwkeKLAKSQVWVAIINAQPVG-----FISRIEHYIDMLFVDPEYTRRGVASALLKPLI-----KSE 104
Cdd:COG2153   18 EQGVPPYLELDG-----KDEDARHLLAYDDGELVAtarllPPGDGEAKIGRVAVLPEYRGQGLGRALMEAAIeeareRGA 92

                         90       100
                 ....*....|....*....|...
gi 446982636 105 SELTVDASITAKPFFERYGFQTV 127
Cdd:COG2153   93 RRIVLSAQAHAVGFYEKLGFVPV 115
Acetyltransf_9 pfam13527
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 6-124 3.12e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 404421 [Multi-domain]  Cd Length: 124  Bit Score: 41.02  E-value: 3.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636    6 IRNYQPGDFQQLCAIFIRAVTMTASQHYspqqisawaqidESRWKEKLAKSQVWVAIINAQPVGFISRIEH--------- 76
Cdd:pfam13527   1 IRPLTEDEFDEVLRLLEYAFQDEDSPEL------------REYFRPLLEEGRVLGAFDDGELVSTLALYPFelnvpgktl 68

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 446982636   77 ---YIDMLFVDPEYTRRGVASALLKPLIKSESELTVDASI---TAKPFFERYGF 124
Cdd:pfam13527  69 paaGITGVATYPEYRGRGVMSRLLRRSLEEMRERGVPLSFlypSSYPIYRRFGY 122
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 1-135 1.40e-04

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 39.98  E-value: 1.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   1 MNNIQIRNYQPGDFQQLCAIFIRAVTM--TASQHYSPQQisAWAQIDESRWKEKLAKSQVWVAIINA--QPVGFIS---- 72
Cdd:COG1670    5 TERLRLRPLRPEDAEALAELLNDPEVAryLPGPPYSLEE--ARAWLERLLADWADGGALPFAIEDKEdgELIGVVGlydi 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446982636  73 -RIEHYIDM-LFVDPEYTRRGVASALLKPLIkseseltvdasitakpffeRYGFQTVKQQRVECR 135
Cdd:COG1670   83 dRANRSAEIgYWLAPAYWGKGYATEALRALL-------------------DYAFEELGLHRVEAE 128
PRK10140 PRK10140
N-acetyltransferase;
1-125 1.77e-04

N-acetyltransferase;


Pssm-ID: 182263 [Multi-domain]  Cd Length: 162  Bit Score: 39.58  E-value: 1.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   1 MNNIQIRNYQPGDFQQlcaifIRAVTMTASQHYSPQQISawaQIDESRWKEKLAKS---QVWVAIINAQPVGFIS----- 72
Cdd:PRK10140   1 MSEIVIRHAETRDYEA-----IRQIHAQPEVYHNTLQVP---HPSDHMWQERLADRpgiKQLVACIDGDVVGHLTidvqq 72

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446982636  73 --RIEHYIDM-LFVDPEYTRRGVASALLKPLIK--------SESELTVDA-SITAKPFFERYGFQ 125
Cdd:PRK10140  73 rpRRSHVADFgICVDSRWKNRGVASALMREMIEmcdnwlrvDRIELTVFVdNAPAIKVYKKYGFE 137
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
58-127 1.78e-04

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 38.35  E-value: 1.78e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446982636  58 VWVAIINAQPVGFIsriehYIDMLFVDPEYTRRGVASALLKPLIKSESE-------LTVD-ASITAKPFFERYGFQTV 127
Cdd:COG3393    3 VAMAGVRAESPGVA-----EISGVYTHPEYRGRGLASALVAALAREALArgartpfLYVDaDNPAARRLYERLGFRPV 75
Spm_actase_Thplmales NF041158
spermidine N(1)-acetyltransferase;
4-106 2.07e-03

spermidine N(1)-acetyltransferase;


Pssm-ID: 469070  Cd Length: 115  Bit Score: 36.06  E-value: 2.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   4 IQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQISAWaqIDESRWKEKL----AKSQVWVAII------NAQPVGFI-- 71
Cdd:NF041158   2 ITIRKLSAEDVDALIEVARESWKWTYRDIYSNEFIESW--ISEKYSKEKLlneiIRSQSNLDIIflgafvNSALIGFIel 79

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 446982636  72 ----SRIEhyIDMLFVDPEYTRRGVASALLkplikSESE 106
Cdd:NF041158  80 kiiaDKAE--LLRLYLKPEYTHRGIGKLLL-----SEAE 111
Eis COG4552
Predicted acetyltransferase [General function prediction only];
4-98 7.09e-03

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443616 [Multi-domain]  Cd Length: 393  Bit Score: 35.64  E-value: 7.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446982636   4 IQIRNYQPGDFQQLCAIFIRAVTMTASQHyspqqisawaqiDESRWKEKLAKSQVWVAIINAQPVGFISRIEH------- 76
Cdd:COG4552    1 MEIRPLTEDDLDAFARLLAYAFGPEPDDE------------ELEAYRPLLEPGRVLGVFDDGELVGTLALYPFtlnvgga 68

                         90       100
                 ....*....|....*....|....*..
gi 446982636  77 -----YIDMLFVDPEYTRRGVASALLK 98
Cdd:COG4552   69 rvpmaGITGVAVAPEHRRRGVARALLR 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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