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Conserved domains on  [gi|446990565|ref|WP_001067821|]
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MULTISPECIES: IS6 family transposase, partial [Gammaproteobacteria]

Protein Classification

IS6 family transposase( domain architecture ID 11462356)

IS6 family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0032196|GO:0015074|GO:0006310|GO:0004803
PubMed:  33757578|31486766|20215432|11774877|20615441

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Rve COG3316
Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];
1-87 7.15e-46

Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];


:

Pssm-ID: 442545 [Multi-domain]  Cd Length: 235  Bit Score: 146.59  E-value: 7.15e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446990565   1 MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAPEMEKRLRWYWRNPSDLcpWHMDET 80
Cdd:COG3316    1 MVDFKGRRFPPEIILLAVRLYLRYGLSLRDVEEMLAERGVDVSHSTIYRWVQKFAPLIAKRLRRRRPPLSDS--WHVDET 78


                 ....*..
gi 446990565  81 YVKVNGR 87
Cdd:COG3316   79 YIKIKGK 85
 
Name Accession Description Interval E-value
Rve COG3316
Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];
1-87 7.15e-46

Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];


Pssm-ID: 442545 [Multi-domain]  Cd Length: 235  Bit Score: 146.59  E-value: 7.15e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446990565   1 MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAPEMEKRLRWYWRNPSDLcpWHMDET 80
Cdd:COG3316    1 MVDFKGRRFPPEIILLAVRLYLRYGLSLRDVEEMLAERGVDVSHSTIYRWVQKFAPLIAKRLRRRRPPLSDS--WHVDET 78


                 ....*..
gi 446990565  81 YVKVNGR 87
Cdd:COG3316   79 YIKIKGK 85
transpos_IS6 NF033587
IS6 family transposase;
4-87 4.33e-43

IS6 family transposase;


Pssm-ID: 411209 [Multi-domain]  Cd Length: 203  Bit Score: 138.48  E-value: 4.33e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446990565   4 FKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAPEMEKRLRWYWRNPSDlcPWHMDETYVK 83
Cdd:NF033587   1 FKRERFPPEIILLAVRLYLRGPLSLRDVEEILAERGVSVSHSTIYRWVHKYAPQLAKRLRRRKPRPPD--SWAVDETVIK 78


                 ....
gi 446990565  84 VNGR 87
Cdd:NF033587  79 INGK 82
DDE_Tnp_IS66 pfam03050
Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. ...
 16-84 2.53e-03

Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.


Pssm-ID: 427113 [Multi-domain]  Cd Length: 281  Bit Score: 34.92  E-value: 2.53e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446990565   16 WAVRWYCKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAP-------EMEKRLRwywrnPSDLCpwHMDETYVKV 84
Cdd:pfam03050  11 LILVLKYADHLPLYRQEDILARLGVELSRGTLANWVGRAAElleplvdALRAALL-----ESPVI--HADETPLRV 79
transpos_IS630 NF033545
IS630 family transposase;
17-57 6.52e-03

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 33.77  E-value: 6.52e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 446990565  17 AVRWYCKYGISYRELQEMLaergvNVDHSTIYRWVQRYAPE 57
Cdd:NF033545   4 RILLLAAEGLSITEIAERL-----GVSRSTVYRWLKRFNEG 39
 
Name Accession Description Interval E-value
Rve COG3316
Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];
1-87 7.15e-46

Transposase (or an inactivated derivative), DDE domain [Mobilome: prophages, transposons];


Pssm-ID: 442545 [Multi-domain]  Cd Length: 235  Bit Score: 146.59  E-value: 7.15e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446990565   1 MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAPEMEKRLRWYWRNPSDLcpWHMDET 80
Cdd:COG3316    1 MVDFKGRRFPPEIILLAVRLYLRYGLSLRDVEEMLAERGVDVSHSTIYRWVQKFAPLIAKRLRRRRPPLSDS--WHVDET 78


                 ....*..
gi 446990565  81 YVKVNGR 87
Cdd:COG3316   79 YIKIKGK 85
transpos_IS6 NF033587
IS6 family transposase;
4-87 4.33e-43

IS6 family transposase;


Pssm-ID: 411209 [Multi-domain]  Cd Length: 203  Bit Score: 138.48  E-value: 4.33e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446990565   4 FKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAPEMEKRLRWYWRNPSDlcPWHMDETYVK 83
Cdd:NF033587   1 FKRERFPPEIILLAVRLYLRGPLSLRDVEEILAERGVSVSHSTIYRWVHKYAPQLAKRLRRRKPRPPD--SWAVDETVIK 78


                 ....
gi 446990565  84 VNGR 87
Cdd:NF033587  79 INGK 82
COG3436 COG3436
Transposase [Mobilome: prophages, transposons];
15-87 1.92e-03

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442662 [Multi-domain]  Cd Length: 416  Bit Score: 35.39  E-value: 1.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446990565  15 LWAVRWYCKY--GISYRELQEMLAERGVNVDHSTIYRWVQRYAP-------EMEKRLRWYWRnpsdlcpWHMDETYVKVN 85
Cdd:COG3436  149 LLAHILVSKFvdHLPLYRQEEIFARLGVELSRSTLLNWVGRAAElleplleGLDERLLAAPV-------LHADETPVQVL 221


                 ..
gi 446990565  86 GR 87
Cdd:COG3436  222 DE 223
DDE_Tnp_IS66 pfam03050
Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. ...
 16-84 2.53e-03

Transposase IS66 family; Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.


Pssm-ID: 427113 [Multi-domain]  Cd Length: 281  Bit Score: 34.92  E-value: 2.53e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446990565   16 WAVRWYCKYGISYRELQEMLAERGVNVDHSTIYRWVQRYAP-------EMEKRLRwywrnPSDLCpwHMDETYVKV 84
Cdd:pfam03050  11 LILVLKYADHLPLYRQEDILARLGVELSRGTLANWVGRAAElleplvdALRAALL-----ESPVI--HADETPLRV 79
transpos_IS630 NF033545
IS630 family transposase;
17-57 6.52e-03

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 33.77  E-value: 6.52e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 446990565  17 AVRWYCKYGISYRELQEMLaergvNVDHSTIYRWVQRYAPE 57
Cdd:NF033545   4 RILLLAAEGLSITEIAERL-----GVSRSTVYRWLKRFNEG 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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