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Conserved domains on  [gi|447046056|ref|WP_001123312|]
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DUF393 domain-containing protein [Staphylococcus aureus]

Protein Classification

thiol-disulfide oxidoreductase DCC family protein( domain architecture ID 10514171)

thiol-disulfide oxidoreductase DCC family protein is a DUF393 domain-containing protein, which may catalyze protein disulfide bond formation or reduction, and is a member of the DCC family of the thioredoxin superfamily

Gene Ontology:  GO:0015035
PubMed:  15236740

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DCC1-like pfam04134
DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved ...
 4-111 1.34e-26

DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved cysteine residues within the DxxCxxC motif at the N-terminal. This motif is conserved in the thiol-disulfide oxidoreductase family. This family includes At5g50100 (also known as DCC1) from Arabidopsis thaliana, a thioredoxin that modulates ROS homeostasis resulting in de novo shoot initiation and may be involved in the improvement of the capacity of plant regeneration. Uncharacterized proteins from bacteria are also included in this family.


:

Pssm-ID: 461189  Cd Length: 112  Bit Score: 95.84  E-value: 1.34e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447046056    4 VYYDGNCIYCYNYVIWLIQHELPRNYQFATLKGEVGQQFFKQH-PEAANKNSVILQKGDRIYFESQAIIKLITALPNRTK 82
Cdd:pfam04134   1 VFYDGVCPLCNREVRFLIRRDRKGRIRFVDLQSAPGFALLKEYgIDLEDADSRLHVERGRVYSGSDAFLAIWRALGGPWR 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 447046056   83 LLGVGLWL-VPKPVRNFGYRMFANNRNRMW 111
Cdd:pfam04134  81 WLAALLRLpGLRPLRDRAYRLFARNRYRWF 110
 
Name Accession Description Interval E-value
DCC1-like pfam04134
DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved ...
 4-111 1.34e-26

DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved cysteine residues within the DxxCxxC motif at the N-terminal. This motif is conserved in the thiol-disulfide oxidoreductase family. This family includes At5g50100 (also known as DCC1) from Arabidopsis thaliana, a thioredoxin that modulates ROS homeostasis resulting in de novo shoot initiation and may be involved in the improvement of the capacity of plant regeneration. Uncharacterized proteins from bacteria are also included in this family.


Pssm-ID: 461189  Cd Length: 112  Bit Score: 95.84  E-value: 1.34e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447046056    4 VYYDGNCIYCYNYVIWLIQHELPRNYQFATLKGEVGQQFFKQH-PEAANKNSVILQKGDRIYFESQAIIKLITALPNRTK 82
Cdd:pfam04134   1 VFYDGVCPLCNREVRFLIRRDRKGRIRFVDLQSAPGFALLKEYgIDLEDADSRLHVERGRVYSGSDAFLAIWRALGGPWR 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 447046056   83 LLGVGLWL-VPKPVRNFGYRMFANNRNRMW 111
Cdd:pfam04134  81 WLAALLRLpGLRPLRDRAYRLFARNRYRWF 110
YuxK COG3011
Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];
1-110 1.40e-21

Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];


Pssm-ID: 442248  Cd Length: 133  Bit Score: 83.47  E-value: 1.40e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447046056   1 MPIVYYDGNCIYCYNYVIWLIQHELPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGD-RIYFESQAIIKLITALPN 79
Cdd:COG3011    8 KPIVLYDGVCPLCNREVRFLLRRDRAGRFRFVPLQSEDGQLAAPGLDPEDLLDSLHLIDEDgRVYTGSDAVLRILRALGG 87

                         90       100       110
                 ....*....|....*....|....*....|..
gi 447046056  80 RTKLLGVGLWL-VPKPVRNFGYRMFANNRNRM 110
Cdd:COG3011   88 PWRLLAALLRLpGLRPLRDRLYRLVARNRYRL 119
 
Name Accession Description Interval E-value
DCC1-like pfam04134
DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved ...
 4-111 1.34e-26

DCC1-like thiol-disulfide oxidoreductase; Members of this family have two highly conserved cysteine residues within the DxxCxxC motif at the N-terminal. This motif is conserved in the thiol-disulfide oxidoreductase family. This family includes At5g50100 (also known as DCC1) from Arabidopsis thaliana, a thioredoxin that modulates ROS homeostasis resulting in de novo shoot initiation and may be involved in the improvement of the capacity of plant regeneration. Uncharacterized proteins from bacteria are also included in this family.


Pssm-ID: 461189  Cd Length: 112  Bit Score: 95.84  E-value: 1.34e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447046056    4 VYYDGNCIYCYNYVIWLIQHELPRNYQFATLKGEVGQQFFKQH-PEAANKNSVILQKGDRIYFESQAIIKLITALPNRTK 82
Cdd:pfam04134   1 VFYDGVCPLCNREVRFLIRRDRKGRIRFVDLQSAPGFALLKEYgIDLEDADSRLHVERGRVYSGSDAFLAIWRALGGPWR 80

                          90       100       110
                  ....*....|....*....|....*....|
gi 447046056   83 LLGVGLWL-VPKPVRNFGYRMFANNRNRMW 111
Cdd:pfam04134  81 WLAALLRLpGLRPLRDRAYRLFARNRYRWF 110
YuxK COG3011
Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];
1-110 1.40e-21

Predicted thiol-disulfide oxidoreductase YuxK, DCC family [General function prediction only];


Pssm-ID: 442248  Cd Length: 133  Bit Score: 83.47  E-value: 1.40e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447046056   1 MPIVYYDGNCIYCYNYVIWLIQHELPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGD-RIYFESQAIIKLITALPN 79
Cdd:COG3011    8 KPIVLYDGVCPLCNREVRFLLRRDRAGRFRFVPLQSEDGQLAAPGLDPEDLLDSLHLIDEDgRVYTGSDAVLRILRALGG 87

                         90       100       110
                 ....*....|....*....|....*....|..
gi 447046056  80 RTKLLGVGLWL-VPKPVRNFGYRMFANNRNRM 110
Cdd:COG3011   88 PWRLLAALLRLpGLRPLRDRLYRLVARNRYRL 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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