|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10367 |
PRK10367 |
DNA-damage-inducible SOS response protein; Provisional |
1-441 |
0e+00 |
|
DNA-damage-inducible SOS response protein; Provisional
Pssm-ID: 182413 [Multi-domain] Cd Length: 441 Bit Score: 698.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 1 MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAK 80
Cdd:PRK10367 1 MAFLTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 81 NPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA 160
Cdd:PRK10367 81 NPQALARALVQPLLLALGAGALIALLRTPLIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 161 PVILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD 240
Cdd:PRK10367 161 PVILLVVGNILNIVLDLWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKVLKLRGISLEMLKTAWRGNFRRLLALNRD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 241 IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGI 320
Cdd:PRK10367 241 IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 321 VALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFA 400
Cdd:PRK10367 321 VALLFSLVYALAGEHIIALLTSLPQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLT 400
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 447050856 401 LPVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS 441
Cdd:PRK10367 401 LPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT 441
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
7-430 |
1.10e-127 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 375.75 E-value: 1.10e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 7 SDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALA 86
Cdd:cd13136 1 LHREILALALPAILSNITVPLLGLVDTAVVGHLGSAAYLGAVALGTTIFNTLFWLFGFLRMGTTGLVAQALGAGDREEAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 87 RALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLV 166
Cdd:cd13136 81 ALLVRALLLALAIGLLLILLQSPLLALALLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLILQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 167 VGNILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGnVRRLLALNRDIMLRSL 246
Cdd:cd13136 161 VGNVVNIVLDPLFVFGLGWGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLSRRLPSKAA-LKRLFKLNRDIFIRTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 247 LLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALLFS 326
Cdd:cd13136 240 ALLAAFLFFTALAARLGDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGLGVLLA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 327 TVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFAL-PVLG 405
Cdd:cd13136 320 LLFFLGGEPIIRLFTDDPAVLALAATYLPWLALLPPIGALAFVLDGIFIGATDTRYLRNSMLVSLAVFLPLLFLLvPLWG 399
|
410 420
....*....|....*....|....*
gi 447050856 406 NHGLWLALTVFLALRGLSLSLIWRR 430
Cdd:cd13136 400 NHGLWLALILFMLLRGLTLALRLPR 424
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
9-424 |
2.31e-74 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 238.89 E-value: 2.31e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:COG0534 8 KLLLRLALPIILGNLLQSLYGLVDTIFVGRL-GTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGDREEARRV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
Cdd:COG0534 87 LGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTPMIIMLIG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 169 NILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRgNVRRLLALNRDIMLRSLLL 248
Cdd:COG0534 167 NVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLRLRLRDLRPDRK-ILKRILRIGLPAGLQQLAE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 249 QLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALLFSTV 328
Cdd:COG0534 246 SLGFLVLNALVARLGTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGIGLLLALL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 329 YALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFAL---TLFALPVLG 405
Cdd:COG0534 326 LFLFPEPIIGLFTDDPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLplaYLLAFLGLG 405
|
410
....*....|....*....
gi 447050856 406 NHGLWLALTVFLALRGLSL 424
Cdd:COG0534 406 LTGVWLALPIGEVLRALLL 424
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
17-358 |
1.63e-71 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 229.05 E-value: 1.63e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 17 PMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARALIQPLLLA 96
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHL-GPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 97 LGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIALD 176
Cdd:TIGR00797 80 LLLGLPVLLVGYFFIDPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 177 LWLVMGLH--MNVQGAALATVIAEYATLLIGFMMVRKvLHLRGVSLDMLKQAWRGNVRRLLALNRDIMLRSLLLQLCFGA 254
Cdd:TIGR00797 160 YILIFGKFgfLGIVGAALATVISYWLMFLLLLYYIKK-AKKIGLKWEGLLKPDWEVLKRLLKLGLPIAFRVILESLSFAL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 255 ITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALLFSTVYALAGE 334
Cdd:TIGR00797 239 LALLVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILFRE 318
|
330 340
....*....|....*....|....
gi 447050856 335 HIVALLTSLPQIQLLADRYLIWQV 358
Cdd:TIGR00797 319 FIARLFTNDPEVLELAAIYLIFVA 342
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
15-429 |
2.61e-46 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 165.19 E-value: 2.61e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 15 ALPMIFSNITVPLLGLVDTAVIGHLDSpVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARALIQPLL 94
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLG-DALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 95 LALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIA 174
Cdd:cd12082 80 LAILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNIL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 175 LDLWLVMGL---HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKqAWRGNVRRLLALNRDIMLRSLLLQLC 251
Cdd:cd12082 160 LDPLLIFGLgppELGIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSLLK-PDLELLRRLLRIGLPSAIQNSLLSLG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 252 FGAIT-VSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALLFSTVYA 330
Cdd:cd12082 239 LLIIVaIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLIL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 331 LAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRA--AEMRNSMAVAAGGFALTLFALPV-LGNH 407
Cdd:cd12082 319 LFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTlkSLIVSLLSYWVVRLPLAYVLAYLgLGLY 398
|
410 420
....*....|....*....|..
gi 447050856 408 GLWLALTVFLALRGLSLSLIWR 429
Cdd:cd12082 399 GIWLALVISLILAALVLLLFFR 420
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
9-437 |
3.13e-33 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 129.55 E-value: 3.13e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:cd13137 1 RRIWSLAWPVILENLLQTLVGLVDVFMVGRL-GAEAIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
Cdd:cd13137 80 LGQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 169 NILNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGnVRRLLALNRDIMLR 244
Cdd:cd13137 160 NVLNIVLDYVLIFGLwgfpGLGVAGAALATVISRVVGALLLLFLLLRGRLPIKISFKGFRLDRKI-IKKLLRIGLPAGLE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 245 SLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALL 324
Cdd:cd13137 239 QLLRSLGFLVLLAIVASYGTAALAAYQIGLRIESLAFMPGFGFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMGL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 325 FSTVYALAGEHIVALLTSLPQIQLLADRYLIW----QVVLPLVGVWCYLLDGMfiGATRAAEMRN--SMAVAAGGFALTL 398
Cdd:cd13137 319 LGLLLFIFAPPLASLFTPDPEVIELGVLYLRIvalsQPFLAISFVLSGALRGA--GDTRPPLIINliSMWLVRLPLAYLL 396
|
410 420 430
....*....|....*....|....*....|....*....
gi 447050856 399 FALPVLGNHGLWLALTVFLALRGLslsLIWRRHWReGTW 437
Cdd:cd13137 397 GFVLGLGLTGIWLAMFVDTIVRAI---LLLYRFRK-GKW 431
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-430 |
4.36e-32 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 126.49 E-value: 4.36e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:cd13133 5 REILKIALPLVLSMLSQTVMGFTDRAFLGRL-SEVALAASGPAGVLYFAILMLFFGLSSGVQVFVAQYNGAGRYSRIGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
Cdd:cd13133 84 LWQGLYFSLLLAPLLALLSALAAPLLFLLLGHSPEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMVANLVM 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 169 NILNIALDLWLVMG----LHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRDIMLR 244
Cdd:cd13133 164 VVVNIVLDYALIFGklgfPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKNRRRFGLRRAWRFDRELLRRILRLGLPSGLQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 245 SLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALL 324
Cdd:cd13133 244 FFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLALAYMLL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 325 FSTVYALAGEHIVALLTSLPQIQLLADryliwQVVLPLVGVWCY-LLDGMFI---------GATRAAeMRNSMAVAAGGF 394
Cdd:cd13133 324 LGILFLLFPELLLSIFTPGADFALIAE-----LAVPLLRFVAAYiLFDALALvfagalrgaGDTRFV-MLAELIVAWLYL 397
|
410 420 430
....*....|....*....|....*....|....*...
gi 447050856 395 ALTLFALPVL--GNHGLWLALTVFLALRGLSLSLIWRR 430
Cdd:cd13133 398 LPPAYLLVVLgaGLAGAWTVETVYVIVLALIFLLRFRS 435
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
9-415 |
2.81e-31 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 124.16 E-value: 2.81e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:cd13143 4 KLFLKFALPAIIGMLVNGLYNIVDGIFVGHGVGALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKANRI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
Cdd:cd13143 84 FSTALLLSLILGLLLTILGLLFLDPLLRLLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAMLGMLIG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 169 NILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRgNVRRLLALNRDIMLRSLLL 248
Cdd:cd13143 164 AVLNIILDPLFIFVLGLGIAGAALATVIAQLISLLLLLLYFFRGKSLLKLSLLRFKLSLK-IIKEILALGFPSFLMQLSS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 249 QLCFGAITVSGARLGSDI-IAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALLFST 327
Cdd:cd13143 243 SVVTIVLNLTLLGYGGDIgVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIYGLVLFL 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 328 VYALAGEHIVALLTSLPQIQLLADRYLIWQVV-LPLVGVwCYLLDGMFIGATRAaemRNSMAVAAGG----FALTLFALP 402
Cdd:cd13143 323 ILLLFPEQIVSLFTDDPELIALAARILRIFLLaFPLAGI-NIVLSGYFQAIGKA---KRAALLSLLRqglfLIPLLLILP 398
|
410
....*....|....
gi 447050856 403 -VLGNHGLWLALTV 415
Cdd:cd13143 399 rLFGLDGIWLAFPL 412
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
9-377 |
5.53e-31 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 123.34 E-value: 5.53e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:cd13138 3 KTLLLFALPLLLSNLLQQLYNLVDLLIVGQFLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAKKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
Cdd:cd13138 83 VGTLLVLFLILGIVLTILGLLFAPPILRLMNTPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFVIIA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 169 NILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGFMMVRK-----VLHLRGVSLDMLKqawrgnVRRLLALNRDIML 243
Cdd:cd13138 163 CVLNIILDLLFIAVFHMGVAGAALATVIAQAISVLLALYYLRKkklpfKLSLKDFRFDKEI------LKEILKIGLPSAL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 244 RSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVAL 323
Cdd:cd13138 237 QQSLVSISFLIINSIVNSYGVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGL 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 447050856 324 LFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVV-LPLVGVwCYLLDGMFIGA 377
Cdd:cd13138 317 IIILLVFFFAPQLLGLFTSDPEVIEIGAEYLRIYSIdYILFGI-LFVFNGLFRGL 370
|
|
| MATE_NorM_like |
cd13131 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio ... |
9-433 |
1.89e-28 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Vibrio cholerae NorM and functions most likely as a multidrug efflux pump, removing xenobiotics from the interior of the cell. The pump utilizes a cation gradient across the membrane to facilitate the export process. NorM appears to bind monovalent cations in an outward-facing conformation and may subsequently cycle through an inward-facing and outward-facing conformation to capture and release its substrate.
Pssm-ID: 240536 [Multi-domain] Cd Length: 435 Bit Score: 116.44 E-value: 1.89e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:cd13131 3 RALLRLALPILIAQLAQMAMGFVDTVMAGRL-GADDLAAVALGSSLWFPVFTFGMGLLLAVTPLVAQAHGAGDRRRIRRA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGV--MIVLFrtpLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLV 166
Cdd:cd13131 82 VRQGLWLALLLSLplMLLLW---LAPPILPLMGQEPEVAAIARGYLLALAWGIPPALLFQVLRSFLDALGRTRPAMVITL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 167 VGNILNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLdmLKQAWRGN---VRRLLALNR 239
Cdd:cd13131 159 LALVLNIPLNYVLIFGKfglpALGGAGAGLATAIVYWLMFLALAFYIRRHKRFRRYRL--FARFWRPDwarLKELLRLGL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 240 DIMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSG 319
Cdd:cd13131 237 PIGLTIFFEVSLFAAVALLMGRLGTTVLAAHQIALNFASLLFMVPLGISMAATVRVGFALGAGDPADARRAGLVGLGLGV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 320 IVALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATraaEMRNSMAVAAGGFAltLF 399
Cdd:cd13131 317 GFAALTALLLLLFPEQIAGLYTNDPAVIALAASLLVFAALFQLFDGIQVVAAGALRGYK---DTRVPFLLALISYW--GI 391
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 447050856 400 ALPV---------LGNHGLWLALTVFLALRGLSLSLIWRRHWR 433
Cdd:cd13131 392 GLPLgyllafttgLGAFGVWIGLIIGLALAAILLLWRFRRLQR 434
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
8-441 |
3.31e-21 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 95.26 E-value: 3.31e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 8 DKALWRLALPMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALAR 87
Cdd:cd13134 2 KLSLFALAWPIFIELLLQMLLGTIDTFMLSRY-SDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKARQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 88 ALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVV 167
Cdd:cd13134 81 IAGVALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSLI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 168 GNILNIALDLWLVMGLH----MNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRgNVRRLLALNRDIML 243
Cdd:cd13134 161 MNILNIVGNYLLIFGWFglpkLGVAGVAISTVISRAVGLVLLFILLFRKLKIRFRLKDLRPFPKK-LLKKILKIGLPSAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 244 RSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVAL 323
Cdd:cd13134 240 EELSYNLSQTVITAFIARLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIGLLVSL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 324 LFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYlldgMFIGATRAA-EMRNSMAVAAG---GFALTL- 398
Cdd:cd13134 320 AVALLLALFREPILGLFTDDPEIIALGKTLLLISILLEPGRAFNI----VLIGSLRAAgDARFPVLIGIIsmwGISVPLa 395
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 447050856 399 --FALPV-LGNHGLWLALTVFLALRGlslsLIWRRHWREGTWFARS 441
Cdd:cd13134 396 ylLGIVLgLGLLGVWIAFAADEWVRG----IIMLWRWRSGKWIKKA 437
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-434 |
4.09e-19 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 89.12 E-value: 4.09e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALP-MIFSNITVpLLGLVDTAVIGHLDSpVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALAR 87
Cdd:cd13140 5 KTLLRLALPiMGTSFIQM-AYNLTDMFWVGRLGS-DAVAAVGTAGFFVWLAYALALLSKIGAQVKVSQSIGAKDEKEARK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 88 ----ALIQPLLLALGAGVMIVLFRTPLIELaLHIvgGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVI 163
Cdd:cd13140 83 yarnALQLNLLLGILYGLLLLLFAKPLIGF-FNL--GDAEVISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTPFI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 164 LLVVGNILNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGvSLDMLKQAWRGNVRRLLALNR 239
Cdd:cd13140 160 INAIGLVLNIILDPLLIFGFgpfpALGVAGAALATVLAQAIVFLLFLYALKKKKGLFL-KIRILKRPDRKYIKEILKLGL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 240 DIMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSG 319
Cdd:cd13140 239 PVALQSILFALISMILARIIASFGPVAIAAQKVGSQIESISWMTAEGFSTALAAFVGQNYGAGKYDRIRKGYKTALKIAS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 320 IVALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIW----QVVLPLVGVwcylLDGMFIGATRaaemrnSMAVAAGGFA 395
Cdd:cd13140 319 AIGLFATLLLFFFGEPLFSLFIPDPETIAIGVDYLRIlgfsQLFMCLEIT----TTGAFNGLGR------TKPPAIISIV 388
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 447050856 396 LT--------LFALPVLGNHGLWLALTVFLALRGLSLSLIWRRHWRE 434
Cdd:cd13140 389 FNglriplalLLSPTGLGLNGIWWAISISSILKGIILTIWFLLYKKK 435
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
17-178 |
1.44e-18 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 82.23 E-value: 1.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 17 PMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARALIQPLLLA 96
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHL-GAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 97 LGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIALD 176
Cdd:pfam01554 80 LLLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPLN 159
|
..
gi 447050856 177 LW 178
Cdd:pfam01554 160 YL 161
|
|
| MATE_eukaryotic |
cd13132 |
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral ... |
9-427 |
5.73e-14 |
|
Eukaryotic members of the multidrug and toxic compound extrusion (MATE) family; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria. This subfamily, which is restricted to eukaryotes, contains vertebrate solute transporters responsible for secretion of cationic drugs across the brush border membranes, yeast proteins located in the vacuole membrane, and plant proteins involved in disease resistance and iron homeostatis under osmotic stress.
Pssm-ID: 240537 [Multi-domain] Cd Length: 436 Bit Score: 73.38 E-value: 5.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPvFLGGVAVG---ATATSFLFMLLLFLRMSTtgLTAQAFGAKNPQAL 85
Cdd:cd13132 3 KKLLRLAAPLVLTSLLQYSLSVVSVVFVGHLGKL-ELAAASLAssfANVTGFSILLGLASALDT--LCGQAFGAKNYKLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 86 ARALIQPLLLALGAGV--MIVLFRTPLIELALHIvggNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVI 163
Cdd:cd13132 80 GVYLQRALVILLLCCVpiSLLWLNTEPILLLLGQ---DPEIARLAGEYLRWLIPGLFAYALFEPLKRYLQAQGIVLPLVY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 164 LLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEY--ATLLIGFMMVRKVLHL--RGVSLDMLkQAWRGNVRrlLALNR 239
Cdd:cd13132 157 ISLVALLLNILLNYLLVFVLGLGFIGAALATSISYWliVVLLLLYIFFSKGHKAtwGGFSREAF-RGWGPFLK--LAIPS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 240 DIMLrsLLLQLCFGAITVSGARLGSDI-IAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQS 318
Cdd:cd13132 234 ALML--CLEWWAFEILVLLAGLLPGTVaLAAQSICLTTTSLLYMIPLGISIAASVRVGNELGAGNPKRAKLAAIVALILS 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 319 GIVALLFSTVYALAGEHIVALLTSLPQIQLLADRyliwqvVLPLVGVwCYLLDGmfIGATRAAEMRNS--MAVAAG--GF 394
Cdd:cd13132 312 LVIGVVVAILLLVLRDVWAYLFTSDEEVIALVAD------LLPILAL-FQIFDG--LQAVLSGVLRGCgrQKLGAYvnLV 382
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 447050856 395 ALTLFALPV---------LGNHGLWLALTVFLALRGLSLSLI 427
Cdd:cd13132 383 AYYLIGLPVglllafvlgLGLKGLWIGLIAGLILQAVILLLI 424
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-359 |
7.47e-13 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 70.01 E-value: 7.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFlggVAVGATATSFLFMLLLFLRMST--TGLTAQAFGAKNPQALA 86
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRISIRYY---SAVGNVTTPFNTITGFLGSISIgfTILGSQSVGAKDIKRIN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 87 RALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLV 166
Cdd:cd13135 78 DYAISSIVYNSIIGVILFLLWLFGARIIFVLFGVDGQILGYSINYVRIFSIYLLLLGILFTFSSILQGIGETKPIMYGGI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 167 VGNILNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLR-GVSLDMLKQAWRGNVRRLLALNRDI 241
Cdd:cd13135 158 IKNLLNVILDYVLIFGNfgfpRLGIIGAAIATTIANVLNLIILVYLCRKIKKLTfKLSNTKVLKANIRPYKFTIKLGLPL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 242 MLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIV 321
Cdd:cd13135 238 GGEEFLWNIGNLAVIRILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEALRIGNICLGLGLLI 317
|
330 340 350
....*....|....*....|....*....|....*...
gi 447050856 322 ALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVV 359
Cdd:cd13135 318 YIAAAIVFLAFPYKILSLFTNDPELINYSIPYLIFIII 355
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-356 |
8.39e-13 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 69.64 E-value: 8.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDS----------PV--FLGGVAVGATAtsflfmlllflrmSTTGLTAQA 76
Cdd:cd13149 9 RHLIKLTLPMIFGILAMLIFNLTDTFFVGKLGTkelaaisftfPVvlFLNSLTIGLGI-------------GASAVISRA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 77 FGAKNPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQ 156
Cdd:cd13149 76 IGAGDRNKAKRLATDSLILSLLLSVIVSLLGLFTIPPLFSLLGASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 157 YARAPVILLVVGNILNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSlDMLKQAWRGNVR 232
Cdd:cd13149 156 DTKRPSLVMLGAALVNVILDPILIFGFgpipGMGIAGAAIATVISRALGLGAALYFLHYHHRLIDFS-EPSLKALFRSWK 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 233 RLLALNRDIMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWR 312
Cdd:cd13149 235 DILSIGIPAALSNILTPLSAAFITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVQEGLK 314
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 447050856 313 AACRQSGIVALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIW 356
Cdd:cd13149 315 ISLKFSLIYGAILGIVLALFAGWLASLFSAEPEVIELITLYLLI 358
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-346 |
4.59e-12 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 67.43 E-value: 4.59e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 11 LWRLALPMIFSNITVPLLGLVDTAVIGHLD--SPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:cd13146 10 LIRLALPILIGQLFQLLYNITDTIWISMIDpsDPALVGGIGLVFPLGMIFLALGNGIQVGVSSLLARAIGAQRAKELDQA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
Cdd:cd13146 90 ADSGLALALLAATVIVVLGYIFAEPLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVLQGEGRTKYMMMAMLIG 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 169 NILNIALDLWLVMGLHMNVQGAALATVIAE---YATLLIGFMMVRKVLHLRgvsLDMLKQAWRgNVRRLLALNRDIMLRS 245
Cdd:cd13146 170 TVVNIVLDPILIFVFDMGVKGAALATVLAQaisLLYLLYVFLIGKSNVTIH---IKLSNISSS-VIVEILRVGLPQMLLQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 246 LLlqlcfgaITVSGARLGSDIIAVNAVLMTLLT-------FTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQS 318
Cdd:cd13146 246 LI-------SSISFLIYNRIIIDIDPVAMTAFTlvgrldqFILIPIFAISSALLTIAGQNWGRGNYDRMLQILMTAVILG 318
|
330 340
....*....|....*....|....*...
gi 447050856 319 GIVALLFSTVYALAGEHIVALLTSLPQI 346
Cdd:cd13146 319 IVVVLVLVLGYVLVAPWLFSLFTTVPEV 346
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-346 |
1.74e-11 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 65.72 E-value: 1.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDS----------PVFLG------GVAVGATAtsflfmlllflrmsttgL 72
Cdd:cd13144 8 RLLLTMSIPAMISMLFQALYNIVDSIFVARLGEnaltavslafPIQNLmiavavGTGVGVNA-----------------L 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 73 TAQAFGAKNPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWL 152
Cdd:cd13144 71 LSRSLGEKDQKEANKAANNGLLLALLSYLLFLLLGLFGVKPFFRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 153 LGVQYARAPVILLVVGNILNIALDLWLVMGLH----MNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWR 228
Cdd:cd13144 151 QSTGNTITPMIAQLIGAIINIILDPILIFGLFgfpaMGIAGAAIATVIGQILAMFLAFFFLLRKNKDVQPDLRLFRPSLR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 229 gNVRRLLALNrdimLRSLLLQlCFGAITVSG-----ARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARD 303
Cdd:cd13144 231 -IIKEIYAVG----LPSIIMQ-AISSVMVFGlnkilAGFGPTAVAVFGIYFKLQSFVFMPVFGLNNGLIPIVAYNYGAGN 304
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 447050856 304 GSKLLDVWRAACRQSGIVALLFSTVYALAGEHIVALLTSLPQI 346
Cdd:cd13144 305 KDRIREAIKYAILIAVVIMLAGGLLFQLFPDQLLGLFNASEEM 347
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
9-349 |
5.87e-10 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 61.02 E-value: 5.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDT-----------AVIGhLDSPVFLG----GVAVGATATSflfmlllflrmsttgLT 73
Cdd:cd13147 9 KAIIKLSIPMIIAMLLQTLYNLVDAiwvaglgadalAAIG-FVFPLFMIiiglGNGLGAGASS---------------AI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 74 AQAFGAKNPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDaVLVQARRFLEIRWLSAPASLANLVLLGWLL 153
Cdd:cd13147 73 SRRIGAKDKEGADNAAVHSILLGLIISIILTIVLLPFLEPILVLMGAGE-VLDLAVDYGRIIFLGSIFLIFNNVAYGILR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 154 GVQYARAPVILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGF--MMVRKVLHLRgVSLDMLKQAWrGNV 231
Cdd:cd13147 152 GEGDTKRAMYAMVAGSILNIILDPIFIYTLGLGIAGAAWATVISMLISSLVLLywFFVKKDTYVS-LSLKNFKFDK-KIV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 232 RRLLALNRDIMLRSLLLQLCFGAITVSGARL-GSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLdv 310
Cdd:cd13147 230 KDILKVGIPASLEQLIMSVLMIILNLILVIVaGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGARNYEKLK-- 307
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 447050856 311 wraacrqsgiVALLFSTVYALAGEHIVALLTSL--PQIQLL 349
Cdd:cd13147 308 ----------TAYNYSIKLGLIIELIIAILIFIfaPQIAYL 338
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-361 |
1.34e-09 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 59.90 E-value: 1.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLdspvflGGVAVGATATS-----FLFMLLLFLRMSTTGLTAQAFGAKNPQ 83
Cdd:cd13142 11 RTLLKLAWPIIVSNLLQVAYNLADTFWLGRL------GADAVAAPSISwplifLFISLGGGLTVAGTALVAQYTGAGDYD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 84 ALARALIQPLLLALGAGVMI----VLFRTPLIELALHIVGgndAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYAR 159
Cdd:cd13142 85 KANKVAGQTFSFVIILSLILavlgYILSRPLLLLLIGAPE---EVYPLALAYLRIIFLGLPFMFIFFVFNSLLRGIGDTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 160 APVILLVVGNILNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWrgnvrRLL 235
Cdd:cd13142 162 TPMKIMFGSVLLNVILDPLLIFGIgpfpGLGVAGAALATVISRGIAAVIGLYLLFKGRVGLKISLRDLKPDW-----EWL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 236 ALNRDIMLRSLLLQ----LCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARdgskllDVW 311
Cdd:cd13142 237 KKIFRIGLPSSIEQsaraLGFTVMTALVAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAG------QID 310
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 447050856 312 RA--ACRQSGIVALLFSTVYALA----GEHIVALLTSLPQIQLLADRYLiwQVVLP 361
Cdd:cd13142 311 RAeeIVKKAALLIFLILVIGGVLaflfAEPIVRVFINDPEVIKEGADFL--RIVAP 364
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
6-354 |
3.40e-09 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 58.39 E-value: 3.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 6 SSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQAL 85
Cdd:cd13139 11 SLNRAIFLLAIPMVLEMVMESLFAVVDLYFVSRL-GALAIATVGLTESVLTIVYSIAIGLSMAATALVARRIGEKDPEGA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 86 ARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILL 165
Cdd:cd13139 90 GFAAVQAILLGVALSLILSILGYFFAEDILSLMGASPAVIAEGYGYTRIMFGGNGFIMLLFLINGIFRGAGDAAIAMRSL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 166 VVGNILNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRgNVRRLLALNRDI 241
Cdd:cd13139 170 WLANGLNIILDPLFIFGLgpipAMGVTGAAIATTIGRSIGVLYQLYHLFKGKGRIQIRRRHLKLDWA-IIKKIIKIAVGG 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 242 MLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLD-VWRAAcRQSGI 320
Cdd:cd13139 249 ILQFLIASSSWIFLVRIIAEFGSTALAGYTIAIRIIMFALLPAWGLSNAAATLVGQNLGAGQPDRAEKsVWRAG-KYNMV 327
|
330 340 350
....*....|....*....|....*....|....
gi 447050856 321 VALLFSTVYALAGEHIVALLTSLPQIQLLADRYL 354
Cdd:cd13139 328 FLGIVSLVFFLFAEPLVSFFTTDPEVIAIAVEAL 361
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-356 |
1.03e-06 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 50.78 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLDSpVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:cd13141 11 KHIISMALPIAIGMIIQTLYFLVDLYFVGQLGD-AALAGVSLAGNVMFFVMALTQVLNVGTAALVSHAVGRKDQGEANAV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLeiRWLSapASLANLVLLGWLLGVQYARA---PVILL 165
Cdd:cd13141 90 FNQSLLLAAVLGLVVLVLGYLFGRLYLETLAADAATVEAATTYL--YWFI--PSLALQFILTVLGAALRGTGivkPFMVI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 166 VVGNI-LNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRgNVRRLLALNRD 240
Cdd:cd13141 166 QILAVlLNIILAPILITGWgtgrALGVAGAGLASSISVAIAVVLLLYYFLRLEKYLRLDLALWRPDLP-TWKRLLKIGLP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 241 IMLRSLLLQLCFGAITVSGARLGSDIIA---VNAVLMTLLTFTAYALdgfAYAVEAHSGQAYGARDGSKLLDVWRAACRQ 317
Cdd:cd13141 245 SGGEFLLTFVYMAVIYWALRPFGAAAQAgfgIGSRIMQSLFLPAMAI---AFAAPAIAGQNFGAGNYDRVRETFRITAIL 321
|
330 340 350
....*....|....*....|....*....|....*....
gi 447050856 318 SGIVALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIW 356
Cdd:cd13141 322 TTALMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRY 360
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-354 |
2.01e-06 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 49.90 E-value: 2.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALP----MIFSNitvpLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQA 84
Cdd:cd13145 9 KLIRKLAIPasvgFFFNT----MFNVVDTFFAGKI-STEALAALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDRRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 85 LARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVIL 164
Cdd:cd13145 84 ARRYAAQGLSFGIILAILLTVIGLFAAPPLFRLLGAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKSYRNF 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 165 LVVGNILNIALDLWLVMG----LHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWRgNVRRLLALNRD 240
Cdd:cd13145 164 LIIGFFLNIILDPLFIFGgggiPAMGVSGIALATIISQFIGMFYLLYKVRKSGIISGCRLRDFIPRLD-VYKEILKQGFP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 241 IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGI 320
Cdd:cd13145 243 ASLNMMTIGLGIFVITYFVGQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAKKYDRVRETYKKALKYGFV 322
|
330 340 350
....*....|....*....|....*....|....
gi 447050856 321 VALLFSTVYALAGEHIVALLTSLPQIQLLADRYL 354
Cdd:cd13145 323 IMVVATVFLLFFAEPLMSLFTNDPAVIAIGAGYL 356
|
|
| vmrA |
PRK09575 |
MATE family efflux transporter; |
5-206 |
2.81e-06 |
|
MATE family efflux transporter;
Pssm-ID: 236576 [Multi-domain] Cd Length: 453 Bit Score: 49.22 E-value: 2.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 5 TSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQA 84
Cdd:PRK09575 8 QSIYRTFWRYTIPSIAAMLVNGLYQIVDGIFIGHYVGAEGLAGINMAWPVIGIILGIGLMVGMGTGSLLSIKRGEGDLEK 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 85 LARALIQPLLLALGAG----VMIVLFRTPLIELAlhivGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA 160
Cdd:PRK09575 88 AKRILTTGLLLLLLLGpivsVILFLFADDFLRAQ----GAEGRTLELALQYIQVLIWGCLFTLGAIALPFLLRNDESPNL 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 447050856 161 PVILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYATLLIGF 206
Cdd:PRK09575 164 ATGLMVIGALINIVLDYLFIGWLDWGLTGAAIATALAQLVVTVLGL 209
|
|
| PRK01766 |
PRK01766 |
multidrug efflux protein; Reviewed |
9-355 |
3.95e-05 |
|
multidrug efflux protein; Reviewed
Pssm-ID: 234981 [Multi-domain] Cd Length: 456 Bit Score: 45.57 E-value: 3.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:PRK01766 12 RQLLALALPILLAQVAQTAMGFVDTVMAGGV-SATDLAAVAIGTSIWLPVILFGHGLLLALTPIVAQLNGAGRRERIAHQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
Cdd:PRK01766 91 VRQGLWLALFLSVLIMLVLYNAVPPILNMMNLEPEVADIAVGYLHALLWGIPAYLLYQVLRSFIDGLGKTKPTMVIGFLG 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 169 NILNIALDLWLVMGL----HMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLdmlkqawrgnVRRLLALNRDIMLR 244
Cdd:PRK01766 171 LLINIPLNYIFIYGKfgfpELGGVGCGVATAIVYWVMFLAMLIYIKRARRFRDFRL----------FKGLYKPDWAVIKR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 245 SLLLQL-----------CFGAITVSGARLGSDIIAVNAVLMTLLTFTaYALD-GFAYAVEAHSGQAYGARDgsklLDVWR 312
Cdd:PRK01766 241 LLKLGLpiglaiffevsLFAVVTLLVSPLGTVTVAAHQIALNFSSLL-FMLPlSLAMALTIRVGFELGAGR----TLDAR 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 447050856 313 AACRQSGIVALLFSTVYA----LAGEHIVALLTSLPQIQLLADRYLI 355
Cdd:PRK01766 316 QYAYIGLAVGLGMALLTAiflvLFREQIALLYTDDPEVVALASHLLL 362
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
241-377 |
5.37e-04 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 40.63 E-value: 5.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 241 IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLldvwRAACRQSGI 320
Cdd:pfam01554 2 IALENLLQSLYSLIDTLFVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRA----GVALRQGLI 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447050856 321 VALLFSTVYALAG----EHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGA 377
Cdd:pfam01554 78 LGLLLSLPIALLVllfsEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQ 138
|
|
| PRK00187 |
PRK00187 |
NorM family multidrug efflux MATE transporter; |
9-429 |
8.46e-04 |
|
NorM family multidrug efflux MATE transporter;
Pssm-ID: 166843 [Multi-domain] Cd Length: 464 Bit Score: 41.65 E-value: 8.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 9 KALWRLALPMIFSNITVPLLGLVDTAVIGHLdSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARA 88
Cdd:PRK00187 10 KAILRLAGPLIASQLAHMLMVFTDTLMMGRL-GPEALAGGGLGAASYSFVSIFCVGVIAAVGTLVAIRHGAGDIEGATRL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 89 LIQPLLLALGAGVMIVLFRTPLIELALHIvGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVG 168
Cdd:PRK00187 89 AQAGLWLAWLLALVAALLLWNLKPLLLLF-GQAPQNVDAAMQFLHLLPFALPGYLSFMALRGFTSALGRAGPVMVISLAG 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 169 NILNIALDLWLVMG------LHMNVQGAALATVIAEYATLLIGFMMVRKVLHLRGVSLDMLKQAWrGNVRRLLALNRDIM 242
Cdd:PRK00187 168 AVANLLLNYALIEGwfglpkLGLMGIGLVTALVSNGMALALALYIRRHPAYAAYPLRKGLSRPSR-AALRELWRLGLPIG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 243 LRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVA 322
Cdd:PRK00187 247 GTYAVEVGLFTFAALCMGALGSTQLAAHQIALQIVSVAFMVPVGLSYAVTMRVGQHYGAGRLLEARRAGRVGIGFGAVVM 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 323 LLFSTVYALAGEHIVALLTSLPQIQLLADRYLIwqVVLPLVGVWCYLLDGM---FIGATRA-AEMRNSMAVAAGGFALT- 397
Cdd:PRK00187 327 LLFAGLFWLLPEAIIGLFLDRNDPAFAEIVQLA--VSLLAVAAWFELFDGTqtiAMGAIRGlKDARTTFLIGLACYWLVg 404
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 447050856 398 -----LFALPV-LGNHGLW--LALTVFLALRGLSLSLIWR 429
Cdd:PRK00187 405 aplawLLAFTLgWGAVGVWwgLALGLACAAVALTLAFEWK 444
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
10-206 |
2.00e-03 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 40.32 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 10 ALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARAL 89
Cdd:COG2244 174 LVLKYSLPLLLSGLLGLLLTNLDRLLLGALLGPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLY 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447050856 90 IQPLLLALGAGVMIVLFRTPLIELALHIVGGNDavLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGN 169
Cdd:COG2244 254 RKALRLLLLLGLPLALGLALLAPPLLSLLFGPE--YAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGA 331
|
170 180 190
....*....|....*....|....*....|....*..
gi 447050856 170 ILNIALDLWLVmgLHMNVQGAALATVIAEYATLLIGF 206
Cdd:COG2244 332 VLNLVLNLLLI--PRYGLVGAAIATLLSYLVLLLLLL 366
|
|
| |
