NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|447090199|ref|WP_001167455|]
View 

MULTISPECIES: hypothetical protein [Escherichia]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Inovirus_Gp2 super family cl20418
Inovirus Gp2; Isoform G2P plays an essential role in viral DNA replication; it binds to the ...
 13-83 2.83e-03

Inovirus Gp2; Isoform G2P plays an essential role in viral DNA replication; it binds to the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII).


The actual alignment was detected with superfamily member pfam11726:

Pssm-ID: 432027  Cd Length: 179  Bit Score: 36.98  E-value: 2.83e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447090199   13 EIRRFIQQAVDHWPRLLAVHFTLHSAE--GNINGQQIHAFCTSFYRQVHERITERNHTASPAPPVVLR--WLREQ 83
Cdd:pfam11726   1 RIDDVIDKALNQYPRLFAVRVDLRLPKdfEDDDTGVITRFFESLKSQLRADFTRKKRRGQRVRECTLRyvWAKEY 75
 
Name Accession Description Interval E-value
Inovirus_Gp2 pfam11726
Inovirus Gp2; Isoform G2P plays an essential role in viral DNA replication; it binds to the ...
 13-83 2.83e-03

Inovirus Gp2; Isoform G2P plays an essential role in viral DNA replication; it binds to the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII).


Pssm-ID: 432027  Cd Length: 179  Bit Score: 36.98  E-value: 2.83e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447090199   13 EIRRFIQQAVDHWPRLLAVHFTLHSAE--GNINGQQIHAFCTSFYRQVHERITERNHTASPAPPVVLR--WLREQ 83
Cdd:pfam11726   1 RIDDVIDKALNQYPRLFAVRVDLRLPKdfEDDDTGVITRFFESLKSQLRADFTRKKRRGQRVRECTLRyvWAKEY 75
 
Name Accession Description Interval E-value
Inovirus_Gp2 pfam11726
Inovirus Gp2; Isoform G2P plays an essential role in viral DNA replication; it binds to the ...
 13-83 2.83e-03

Inovirus Gp2; Isoform G2P plays an essential role in viral DNA replication; it binds to the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII).


Pssm-ID: 432027  Cd Length: 179  Bit Score: 36.98  E-value: 2.83e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447090199   13 EIRRFIQQAVDHWPRLLAVHFTLHSAE--GNINGQQIHAFCTSFYRQVHERITERNHTASPAPPVVLR--WLREQ 83
Cdd:pfam11726   1 RIDDVIDKALNQYPRLFAVRVDLRLPKdfEDDDTGVITRFFESLKSQLRADFTRKKRRGQRVRECTLRyvWAKEY 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH