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Conserved domains on  [gi|447110113|ref|WP_001187369|]
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MULTISPECIES: 2-octaprenyl-6-methoxyphenyl hydroxylase [Acinetobacter]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 5-399 3.26e-112

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01988:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 385  Bit Score: 333.40  E-value: 3.26e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113    5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvAPYHSSFDARNTALSRRSVQIYQKLGLWDALQ-QHATPIL 83
Cdd:TIGR01988   2 IVIVGGGMVGLALALALARSGLKVALIEATPLP-------APADPGFDNRVSALSAASIRLLEKLGVWDKIEpARAQPIR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   84 QVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGDELLKLE 163
Cdd:TIGR01988  75 DIHVSDGGSFGALRFDADEIGLEALGYVVENRVLQQALWERLQELPNVTLLCPARVVELPRHSDHVELTLDDGQQLRARL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  164 SkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFsALGPLALLPLPGEYRRSVVWPVKKgTESE 243
Cdd:TIGR01988 155 L---VGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPHQGTAWERF-TPTGPLALLPLPDNRSSLVWTLPP-EEAE 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  244 WLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVLLRY 323
Cdd:TIGR01988 230 RLLALSDEEFLAELQRAFGSRLGAITLVGERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEV 309

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447110113  324 LVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANYAMG 399
Cdd:TIGR01988 310 LEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
 
Name Accession Description Interval E-value
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 5-399 3.26e-112

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 333.40  E-value: 3.26e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113    5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvAPYHSSFDARNTALSRRSVQIYQKLGLWDALQ-QHATPIL 83
Cdd:TIGR01988   2 IVIVGGGMVGLALALALARSGLKVALIEATPLP-------APADPGFDNRVSALSAASIRLLEKLGVWDKIEpARAQPIR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   84 QVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGDELLKLE 163
Cdd:TIGR01988  75 DIHVSDGGSFGALRFDADEIGLEALGYVVENRVLQQALWERLQELPNVTLLCPARVVELPRHSDHVELTLDDGQQLRARL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  164 SkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFsALGPLALLPLPGEYRRSVVWPVKKgTESE 243
Cdd:TIGR01988 155 L---VGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPHQGTAWERF-TPTGPLALLPLPDNRSSLVWTLPP-EEAE 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  244 WLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVLLRY 323
Cdd:TIGR01988 230 RLLALSDEEFLAELQRAFGSRLGAITLVGERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEV 309

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447110113  324 LVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANYAMG 399
Cdd:TIGR01988 310 LEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 2-400 1.88e-111

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 331.82  E-value: 1.88e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   2 QQQVIIVGGGMVGLSLSLM---LAKANIAVKLLEAVKyPNYDdqnvapYHSSFDARNTALSRRSVQIYQKLGLWDALQQH 78
Cdd:PRK05732   3 RMDVIIVGGGMAGATLALAlsrLSHGGLPVALIEAFA-PESD------AHPGFDARAIALAAGTCQQLARLGVWQALADC 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  79 ATPILQVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGDE 158
Cdd:PRK05732  76 ATPITHIHVSDRGHAGFVRLDAEDYGVPALGYVVELHDVGQRLFALLDKAPGVTLHCPARVANVERTQGSVRVTLDDGET 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 159 LLKLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSalgplallplpgEY---------- 228
Cdd:PRK05732 156 LTGRLL---VAADGSHSALREALGIDWQQHPYEQVAVIANVTTSEAHQGRAFERFT------------EHgplallpmsd 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 229 -RRSVVWPVKKGTESEWLGdENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAG 307
Cdd:PRK05732 221 gRCSLVWCHPLEDAEEVLS-WSDAQFLAELQQAFGWRLGRITHAGKRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAG 299

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 308 QGFNLCLRDADVLLRYLVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIP 387
Cdd:PRK05732 300 QGFNLGLRDVMSLAETLTQALARGEDIGDYAVLQRYQQRRQQDREATIGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLP 379

                        410
                 ....*....|...
gi 447110113 388 GVKPLVANYAMGL 400
Cdd:PRK05732 380 PARDWLARRTLGW 392
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-390 7.97e-65

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 209.79  E-value: 7.97e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvapyhsSFDARNTALSRRSVQIYQKLGLWDALQQHAT 80
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPP------------RPDGRGIALSPRSLELLRRLGLWDRLLARGA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  81 PILQVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPlIELIDGVQVTALTQDAEQVHIEAQRGDell 160
Cdd:COG0654   70 PIRGIRVRDGSDGRVLARFDAAETGLPAGLVVPRADLERALLEAARALG-VELRFGTEVTGLEQDADGVTVTLADGR--- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 161 KLESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTskphenvgferfsalgplallplpgeyrrsvvwpvkkgt 240
Cdd:COG0654  146 TLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVRT--------------------------------------- 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 241 esewlgdendqHFLSALQQtYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVL 320
Cdd:COG0654  187 -----------ELRARLAA-AGPRLGELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAAL 254

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 321 LRYLVNQLSASDDignPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVK 390
Cdd:COG0654  255 AWKLAAALRGRDD---EAALARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 4-357 1.17e-21

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 95.08  E-value: 1.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113    4 QVIIVGGGMVGLSLSLMLAKANIAVKLLEAvkypnYDDQNVAPyhssfdaRNTALSRRSVQIYQKLGLWDALQQHATPIL 83
Cdd:pfam01494   3 DVLIVGGGPAGLMLALLLARAGVRVVLVER-----HATTSVLP-------RAHGLNQRTMELLRQAGLEDRILAEGVPHE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   84 QVHITEQGSFGKARLVAEQ--EKVESFGQVIenawLGRVLLTQVRQQPLiELIDGVQVTALTQDAEQVHIEA--QRGDEL 159
Cdd:pfam01494  71 GMGLAFYNTRRRADLDFLTspPRVTVYPQTE----LEPILVEHAEARGA-QVRFGTEVLSLEQDGDGVTAVVrdRRDGEE 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  160 LKLESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKP-------HENVGFERFSALGPLALLPLPGEYRRSV 232
Cdd:pfam01494 146 YTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDlsdpverAFVHYLIYAPHSRGFMVGPWRSAGRERY 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  233 VWPVKKGTE-SEWLGDENDQHFLSALQQTYGDRAGKFEKTGKRfSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFN 311
Cdd:pfam01494 226 YVQVPWDEEvEERPEEFTDEELKQRLRSIVGIDLALVEILWKS-IWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLN 304

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 447110113  312 LCLRDADVLLRYL--VNQLSASDDIgnpdnLLAYEQARLSDQQRVIKF 357
Cdd:pfam01494 305 TAIQDAFNLAWKLaaVLRGQAGESL-----LDTYSAERLPVAWAVVDF 347
 
Name Accession Description Interval E-value
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 5-399 3.26e-112

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 333.40  E-value: 3.26e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113    5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvAPYHSSFDARNTALSRRSVQIYQKLGLWDALQ-QHATPIL 83
Cdd:TIGR01988   2 IVIVGGGMVGLALALALARSGLKVALIEATPLP-------APADPGFDNRVSALSAASIRLLEKLGVWDKIEpARAQPIR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   84 QVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGDELLKLE 163
Cdd:TIGR01988  75 DIHVSDGGSFGALRFDADEIGLEALGYVVENRVLQQALWERLQELPNVTLLCPARVVELPRHSDHVELTLDDGQQLRARL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  164 SkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFsALGPLALLPLPGEYRRSVVWPVKKgTESE 243
Cdd:TIGR01988 155 L---VGADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPHQGTAWERF-TPTGPLALLPLPDNRSSLVWTLPP-EEAE 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  244 WLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVLLRY 323
Cdd:TIGR01988 230 RLLALSDEEFLAELQRAFGSRLGAITLVGERHAFPLSLTHAKRYVAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEV 309

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447110113  324 LVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANYAMG 399
Cdd:TIGR01988 310 LEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLRNLGLRLLNNLPPLKNFIARYAMG 385
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 2-400 1.88e-111

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 331.82  E-value: 1.88e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   2 QQQVIIVGGGMVGLSLSLM---LAKANIAVKLLEAVKyPNYDdqnvapYHSSFDARNTALSRRSVQIYQKLGLWDALQQH 78
Cdd:PRK05732   3 RMDVIIVGGGMAGATLALAlsrLSHGGLPVALIEAFA-PESD------AHPGFDARAIALAAGTCQQLARLGVWQALADC 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  79 ATPILQVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGDE 158
Cdd:PRK05732  76 ATPITHIHVSDRGHAGFVRLDAEDYGVPALGYVVELHDVGQRLFALLDKAPGVTLHCPARVANVERTQGSVRVTLDDGET 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 159 LLKLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSalgplallplpgEY---------- 228
Cdd:PRK05732 156 LTGRLL---VAADGSHSALREALGIDWQQHPYEQVAVIANVTTSEAHQGRAFERFT------------EHgplallpmsd 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 229 -RRSVVWPVKKGTESEWLGdENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAG 307
Cdd:PRK05732 221 gRCSLVWCHPLEDAEEVLS-WSDAQFLAELQQAFGWRLGRITHAGKRSAYPLALVTAAQQISHRLALVGNAAQTLHPIAG 299

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 308 QGFNLCLRDADVLLRYLVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIP 387
Cdd:PRK05732 300 QGFNLGLRDVMSLAETLTQALARGEDIGDYAVLQRYQQRRQQDREATIGFTDGLVRLFANRWAPLVVGRNLGLMAMDLLP 379

                        410
                 ....*....|...
gi 447110113 388 GVKPLVANYAMGL 400
Cdd:PRK05732 380 PARDWLARRTLGW 392
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 5-399 9.36e-110

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 327.35  E-value: 9.36e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113    5 VIIVGGGMVGLSLSLMLA-KANIAVKLLEAvkypnyddqNVAPY-HSSFDARNTALSRRSVQIYQKLGLWDALQQHATPI 82
Cdd:TIGR01984   2 VIIVGGGLVGLSLALALSrLGKIKIALIEA---------NSPSAaQPGFDARSLALSYGSKQILEKLGLWPKLAPFATPI 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   83 LQVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGdelLKL 162
Cdd:TIGR01984  73 LDIHVSDQGHFGATHLRASEFGLPALGYVVELADLGQALLSRLALLTNIQLYCPARYKEIIRNQDYVRVTLDNG---QQL 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  163 ESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSALGPLALLPLPGEYRRSVVWPVKKgTES 242
Cdd:TIGR01984 150 RAKLLIAADGANSKVRELLSIPTEEHDYNQTALIANIRHEQPHQGCAFERFTPHGPLALLPLKDNYRSSLVWCLPS-KQA 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  243 EWLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVLLR 322
Cdd:TIGR01984 229 DTIANLPDAEFLAELQQAFGWRLGKITQVGERKTYPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGFNLGLRDVETLAE 308

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447110113  323 YLVNqlsASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANYAMG 399
Cdd:TIGR01984 309 VLID---ARIDLGTYALLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPPLKKRLARQAMG 382
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-390 7.97e-65

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 209.79  E-value: 7.97e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvapyhsSFDARNTALSRRSVQIYQKLGLWDALQQHAT 80
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPP------------RPDGRGIALSPRSLELLRRLGLWDRLLARGA 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  81 PILQVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPlIELIDGVQVTALTQDAEQVHIEAQRGDell 160
Cdd:COG0654   70 PIRGIRVRDGSDGRVLARFDAAETGLPAGLVVPRADLERALLEAARALG-VELRFGTEVTGLEQDADGVTVTLADGR--- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 161 KLESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTskphenvgferfsalgplallplpgeyrrsvvwpvkkgt 240
Cdd:COG0654  146 TLRADLVVGADGARSAVRRLLGIGFTGRDYPQRALWAGVRT--------------------------------------- 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 241 esewlgdendqHFLSALQQtYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVL 320
Cdd:COG0654  187 -----------ELRARLAA-AGPRLGELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQGANLALRDAAAL 254

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 321 LRYLVNQLSASDDignPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVK 390
Cdd:COG0654  255 AWKLAAALRGRDD---EAALARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRNAGLRLLDRLPPLK 321
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 1-401 3.74e-58

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 194.99  E-value: 3.74e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQV--IIVGGGMVGLSLSLMLAKANIAVKLLEAvKYPNyDDQNVAPyhssfDARNTALSRRSVQIYQKLGLWDALQQ- 77
Cdd:PRK08850   1 MMQSVdvAIIGGGMVGLALAAALKESDLRIAVIEG-QLPE-EALNELP-----DVRVSALSRSSEHILRNLGAWQGIEAr 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  78 HATPILQVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGd 157
Cdd:PRK08850  74 RAAPYIAMEVWEQDSFARIEFDAESMAQPDLGHIVENRVIQLALLEQVQKQDNVTLLMPARCQSIAVGESEAWLTLDNG- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 158 elLKLESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSALGPLALLPLPGEYRRSVVWPVK 237
Cdd:PRK08850 153 --QALTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVANVRTVDPHNSVARQIFTPQGPLAFLPMSEPNMSSIVWSTE 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 238 KgTESEWLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDA 317
Cdd:PRK08850 231 P-LRAEALLAMSDEQFNKALTAEFDNRLGLCEVVGERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDA 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 318 DVLLRYLVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANYA 397
Cdd:PRK08850 310 ASLAQEILALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389


                 ....
gi 447110113 398 MGLK 401
Cdd:PRK08850 390 LGLK 393
PRK07364 PRK07364
FAD-dependent hydroxylase;
5-401 2.36e-54

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 185.22  E-value: 2.36e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPNYDDQNVApYhssfdarntALSRRSVQIYQKLGLWDALQQHATPILQ 84
Cdd:PRK07364  21 VAIVGGGIVGLTLAAALKDSGLRIALIEAQPAEAAAAKGQA-Y---------ALSLLSARIFEGIGVWEKILPQIGKFRQ 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  85 VHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGDELLKLES 164
Cdd:PRK07364  91 IRLSDADYPGVVKFQPTDLGTEALGYVGEHQVLLEALQEFLQSCPNITWLCPAEVVSVEYQQDAATVTLEIEGKQQTLQS 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 165 KLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFsALGPLALLPLPGEYRRSVVWPVKKGtESEW 244
Cdd:PRK07364 171 KLVVAADGARSPIRQAAGIKTKGWKYWQSCVTATVKHEAPHNDIAYERF-WPSGPFAILPLPGNRCQIVWTAPHA-QAKA 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 245 LGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLsQVLAHKQAVG-RVILMGNAAHTIHPVAGQGFNLCLRDADVLLRY 323
Cdd:PRK07364 249 LLALPEAEFLAELQQRYGDQLGKLELLGDRFLFPV-QLMQSDRYVQhRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQV 327

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447110113 324 LVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANYAMGLK 401
Cdd:PRK07364 328 LQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVVVRRLGLWLLRHVPPLKRLALRLMTGLK 405
PRK09126 PRK09126
FAD-dependent hydroxylase;
5-402 2.44e-53

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 182.06  E-value: 2.44e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLLEavkypnyddqnVAPYHS----SFDARNTALSRRSVQIYQKLGLWDALQQHAT 80
Cdd:PRK09126   6 IVVVGAGPAGLSFARSLAGSGLKVTLIE-----------RQPLAAladpAFDGREIALTHASREILQRLGAWDRIPEDEI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  81 PILQVHITEQGSFGKA-RLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGDEL 159
Cdd:PRK09126  75 SPLRDAKVLNGRSPFAlTFDARGRGADALGYLVPNHLIRRAAYEAVSQQDGIELLTGTRVTAVRTDDDGAQVTLANGRRL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 160 LKLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFsalgplallplpgEYRRSV-VWPVKK 238
Cdd:PRK09126 155 TARLL---VAADSRFSATRRQLGIGADMHDFGRTMLVCRMRHELPHHHTAWEWF-------------GYGQTLaLLPLNG 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 239 GT----------ESEWLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQ 308
Cdd:PRK09126 219 HLsslvltlppdQIEALLALDPEAFAAEVTARFKGRLGAMRLVSSRHAYPLVAVYAHRFVAKRFALIGDAAVGMHPVTAH 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 309 GFNLCLRDADVLLRYLVNQLSASDDIGNPDNLLAYEQArlsdQQRVIK--FCDT--VVRGFSNQNPLLKLIRNTGLIAFD 384
Cdd:PRK09126 299 GFNLGLKGQDILARLILAAARRGQDIGAASLLERYERK----HRLATRplYHATnaIAALYTDDRPPARLLRRAVLRAAN 374

                        410
                 ....*....|....*...
gi 447110113 385 VIPGVKPLVANYAMGLKA 402
Cdd:PRK09126 375 RFPPLKQAIAKQLTGRKK 392
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
1-399 2.84e-52

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 178.99  E-value: 2.84e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvAPYHSSFDARNTALSRRSVQIYQKLGLWDALQqhAT 80
Cdd:PRK07608   4 MKFDVVVVGGGLVGASLALALAQSGLRVALLAPRAPP-------RPADDAWDSRVYAISPSSQAFLERLGVWQALD--AA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  81 PILQVHITEQGSFGKARLV--AEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGvQVTALTQDAEQVHIEAQRGDE 158
Cdd:PRK07608  75 RLAPVYDMRVFGDAHARLHfsAYQAGVPQLAWIVESSLIERALWAALRFQPNLTWFPA-RAQGLEVDPDAATLTLADGQV 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 159 LLKLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFsALGPLALLPLPGEYRRSVVWPVKK 238
Cdd:PRK07608 154 LRADLV---VGADGAHSWVRSQAGIKAERRPYRQTGVVANFKAERPHRGTAYQWF-RDDGILALLPLPDGHVSMVWSART 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 239 GTESEWLGDENDQhFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDAD 318
Cdd:PRK07608 230 AHADELLALSPEA-LAARVERASGGRLGRLECVTPAAGFPLRLQRVDRLVAPRVALVGDAAHLIHPLAGQGMNLGLRDVA 308

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 319 VLLRyLVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANYAM 398
Cdd:PRK07608 309 ALAD-VLAGREPFRDLGDLRLLRRYERARREDILALQVATDGLQRLFALPGPLARWLRNAGMALVGALPLVKRWLVRHAL 387


                 .
gi 447110113 399 G 399
Cdd:PRK07608 388 G 388
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
5-398 3.38e-51

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 176.42  E-value: 3.38e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKA----NIAVKLLEAVkypnyddqnvAPYHSSFDARNTALSRRSVQIYQKLGLWDAlqqHAT 80
Cdd:PRK06996  14 IAIVGAGPVGLALAGWLARRsatrALSIALIDAR----------EPAASANDPRAIALSHGSRVLLETLGAWPA---DAT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  81 PILQVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPlIELIDGVQVTALTQDAEQVHIEAQRGDELL 160
Cdd:PRK06996  81 PIEHIHVSQRGHFGRTLIDRDDHDVPALGYVVRYGSLVAALARAVRGTP-VRWLTSTTAHAPAQDADGVTLALGTPQGAR 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 161 KLESKLLIAADGrDSFCRQAIGVGVDVH--DYDQVAIVTTVQTSKPHENVGFERFSA----LGPLALLPLPGEYrrSVVW 234
Cdd:PRK06996 160 TLRARIAVQAEG-GLFHDQKADAGDSARrrDYGQTAIVGTVTVSAPRPGWAWERFTHegplALLPLGGPRQADY--ALVW 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 235 PVKKGTESEWLGDENDQhFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCL 314
Cdd:PRK06996 237 CCAPDEAARRAALPDDA-FLAELGAAFGTRMGRFTRIAGRHAFPLGLNAARTLVNGRIAAVGNAAQTLHPVAGQGLNLGL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 315 RDADVLLRYLvnqlsaSDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVA 394
Cdd:PRK06996 316 RDAHTLADAL------SDHGATPLALATFAARRALDRRVTIGATDLLPRLFTVDSRPLAHLRGAALTALEFVPPLKHALA 389


                 ....
gi 447110113 395 NYAM 398
Cdd:PRK06996 390 RQMM 393
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
2-400 1.52e-50

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 174.78  E-value: 1.52e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   2 QQQVIIVGGGMVGLSLSLMLAKA--NIAVKLLEAvkypnyddqnvAPYH-SSFDARNTALSRRSVQIYQKLGLWDALQQH 78
Cdd:PRK07333   1 QCDVVIAGGGYVGLALAVALKQAapHLPVTVVDA-----------APAGaWSRDPRASAIAAAARRMLEALGVWDEIAPE 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  79 ATPILQVHITEQGSFGKARLV-----AEQEKVESFGQVIENAWLGRVLLTQVRQQPlIELIDGVQVTALTQDAEQVHIEA 153
Cdd:PRK07333  70 AQPITDMVITDSRTSDPVRPVfltfeGEVEPGEPFAHMVENRVLINALRKRAEALG-IDLREATSVTDFETRDEGVTVTL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 154 QRGDELLKLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSALGPLALLPLPGEyRRSVV 233
Cdd:PRK07333 149 SDGSVLEARLL---VAADGARSKLRELAGIKTVGWDYGQSGIVCTVEHERPHGGRAEEHFLPAGPFAILPLKGN-RSSLV 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 234 WpVKKGTESEWLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLC 313
Cdd:PRK07333 225 W-TERTADAERLVALDDLVFEAELEQRFGHRLGELKVLGKRRAFPLGLTLARSFVAPRFALVGDAAHGIHPIAGQGLNLG 303

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 314 LRDADVLLRYLVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLV 393
Cdd:PRK07333 304 LKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVDRLPKLKSFF 383


                 ....*..
gi 447110113 394 ANYAMGL 400
Cdd:PRK07333 384 IRQAAGL 390
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
5-393 5.56e-47

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 165.42  E-value: 5.56e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPNYddQNVAPyhssfDARNTALSRRSVQIYQKLGLWDA-LQQHATPIL 83
Cdd:PRK08773   9 AVIVGGGVVGAACALALADAGLSVALVEGREPPRW--QADQP-----DLRVYAFAADNAALLDRLGVWPAvRAARAQPYR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  84 QVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPlIELIDGVQVTALTQDAEQVHIeaqRGDELLKLE 163
Cdd:PRK08773  82 RMRVWDAGGGGELGFDADTLGREQLGWIVENDLLVDRLWAALHAAG-VQLHCPARVVALEQDADRVRL---RLDDGRRLE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 164 SKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFsALGPLALLPLPGEYRRSVVWPVKKGtESE 243
Cdd:PRK08773 158 AALAIAADGAASTLRELAGLPVSRHDYAQRGVVAFVDTEHPHQATAWQRF-LPTGPLALLPFADGRSSIVWTLPDA-EAE 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 244 WLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVLLRY 323
Cdd:PRK08773 236 RVLALDEAAFSRELTQAFAARLGEVRVASPRTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQL 315

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 324 LVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPgvkPLV 393
Cdd:PRK08773 316 VRQAHARRADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLP---PLV 382
PRK08013 PRK08013
oxidoreductase; Provisional
 1-400 3.73e-44

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 157.90  E-value: 3.73e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQ-QVIIVGGGMVGLSLSLMLAKANIAVKLLEavkypnyddqNVAPYHSSFDA----RNTALSRRSVQIYQKLGLWDA- 74
Cdd:PRK08013   1 MQSvDVVIAGGGMVGLAVACGLQGSGLRVAVLE----------QRVPEPLAADAppalRVSAINAASEKLLTRLGVWQDi 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  75 LQQHATPILQVHITEQGSFGKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQ 154
Cdd:PRK08013  71 LARRASCYHGMEVWDKDSFGRIAFDDQSMGYSHLGHIIENSVIHYALWQKAQQSSDITLLAPAELQQVAWGENEAFLTLK 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 155 RGDELLKLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSALGPLALLPLPGEYRRSVVW 234
Cdd:PRK08013 151 DGSMLTARLV---VGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGDGILAFLPLSDPHLCSIVW 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 235 PVKkGTESEWLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCL 314
Cdd:PRK08013 228 SLS-PEEAQRMQQAPEEEFNRALAIAFDNRLGLCELESERQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGF 306

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 315 RDADVL---LRYLVNQlsaSDDIGNPDNLLAYEQAR-------LSDQQ--RVIkfcdtvvrgFSNQNPLLKLIRNTGLIA 382
Cdd:PRK08013 307 MDAAELiaeLRRLHRQ---GKDIGQHLYLRRYERSRkhsaalmLAGMQgfRDL---------FAGNNPAKKLLRDIGLKL 374

                        410
                 ....*....|....*...
gi 447110113 383 FDVIPGVKPLVANYAMGL 400
Cdd:PRK08013 375 ADTLPGVKPQLIRQAMGL 392
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 1-400 5.69e-44

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 157.68  E-value: 5.69e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAvkypnyDDQNVAPY--HSSFDARNTALSRRSVQIYQKLGLWDAL-QQ 77
Cdd:PRK05714   1 MRADLLIVGAGMVGSALALALQGSGLEVLLLDG------GPLSVKPFdpQAPFEPRVSALSAASQRILERLGAWDGIaAR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  78 HATPILQVHITEQGSFGKARLVAEQEKVESFGQVIEN----------------AWLGRVLLTQVRQQP---LIELIDGVQ 138
Cdd:PRK05714  75 RASPYSEMQVWDGSGTGQIHFSAASVHAEVLGHIVENrvvqdallerlhdsdiGLLANARLEQMRRSGddwLLTLADGRQ 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 139 VTAltqdaeqvhieaqrgdellklesKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSALGP 218
Cdd:PRK05714 155 LRA-----------------------PLVVAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEPHRATAWQRFTDDGP 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 219 LALLPLPGEYRR---SVVWPVKKgTESEWLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILM 295
Cdd:PRK05714 212 LAFLPLERDGDEhwcSIVWSTTP-EEAERLMALDDDAFCAALERAFEGRLGEVLSADPRLCVPLRQRHAKRYVEPGLALI 290

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 296 GNAAHTIHPVAGQGFNLCLRDADVLLRYLVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFsNQNPL-LKL 374
Cdd:PRK05714 291 GDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEGFERLF-QADPLpLRW 369

                        410       420
                 ....*....|....*....|....*.
gi 447110113 375 IRNTGLIAFDVIPGVKPLVANYAMGL 400
Cdd:PRK05714 370 LRNTGLKLVDQMPEAKALFVRQALGL 395
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
5-350 5.82e-40

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 146.20  E-value: 5.82e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLleavkypnyddqnVAPYHSSFDARNTALSRRSVQIYQKLGLWDALQQHATPILQ 84
Cdd:PRK07494  10 IAVIGGGPAGLAAAIALARAGASVAL-------------VAPEPPYADLRTTALLGPSIRFLERLGLWARLAPHAAPLQS 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  85 VHITEQGS-FGKARLV---AEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDgVQVTALTQDAEQVHIEAQRGDELL 160
Cdd:PRK07494  77 MRIVDATGrLIRAPEVrfrAAEIGEDAFGYNIPNWLLNRALEARVAELPNITRFG-DEAESVRPREDEVTVTLADGTTLS 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 161 KLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFErFSALGPLALLPLPGEYRRSVVWpVKKGT 240
Cdd:PRK07494 156 ARLV---VGADGRNSPVREAAGIGVRTWSYPQKALVLNFTHSRPHQNVSTE-FHTEGGPFTQVPLPGRRSSLVW-VVRPA 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 241 ESEWLGDENDQHFLSALQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVL 320
Cdd:PRK07494 231 EAERLLALSDAALSAAIEERMQSMLGKLTLEPGRQAWPLSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATL 310

                        330       340       350
                 ....*....|....*....|....*....|
gi 447110113 321 LRYLVNqlsASDDIGNPDNLLAYEQARLSD 350
Cdd:PRK07494 311 VEIVED---RPEDPGSAAVLAAYDRARRPD 337
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 1-400 1.33e-38

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 142.82  E-value: 1.33e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQ---VIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPNYDDQNvAPyhssfDARNTALSRRSVQIYQKLGLWDALQQ 77
Cdd:PRK08020   1 MTNQptdIAIVGGGMVGAALALGLAQHGFSVAVLEHAAPAPFDADS-QP-----DVRISAISAASVALLKGLGVWDAVQA 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  78 -HATPILQVHITEQGSfgkARLV--AEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQ 154
Cdd:PRK08020  75 mRSHPYRRLETWEWET---AHVVfdAAELKLPELGYMVENRVLQLALWQALEAHPNVTLRCPASLQALQRDDDGWELTLA 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 155 RGDELLKLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSALGPLALLPLPGEYRrSVVW 234
Cdd:PRK08020 152 DGEEIQAKLV---IGADGANSQVRQMAGIGVHGWQYRQSCMLISVKCENPPGDSTWQQFTPSGPRAFLPLFDNWA-SLVW 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 235 ---PVK----KGTESEWLGDENDQHFLSALQQTYGDRAGkfektgkrfSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAG 307
Cdd:PRK08020 228 ydsPARirqlQAMSMAQLQQEIAAHFPARLGAVTPVAAG---------AFPLTRRHALQYVQPGLALVGDAAHTINPLAG 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 308 QGFNLCLRDADVLLRYLVNQLSASDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIP 387
Cdd:PRK08020 299 QGVNLGYRDVDALLDVLVNARSYGEAWASEAVLKRYQRRRMADNLLMQSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAG 378

                        410
                 ....*....|...
gi 447110113 388 GVKPLVANYAMGL 400
Cdd:PRK08020 379 VLKRQALKYALGL 391
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 5-400 3.49e-35

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 133.36  E-value: 3.49e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPNYDDqnvapyHSSFDARNTALSRRSVQIYQKLGLWDALQQ-HATPIL 83
Cdd:PRK08849   6 IAVVGGGMVGAATALGFAKQGRSVAVIEGGEPKAFEP------SQPMDIRVSAISQTSVDLLESLGAWSSIVAmRVCPYK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  84 QVHITEQGSFgKARLVAEQEKVESFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRGDELLKLE 163
Cdd:PRK08849  80 RLETWEHPEC-RTRFHSDELNLDQLGYIVENRLIQLGLWQQFAQYPNLTLMCPEKLADLEFSAEGNRVTLESGAEIEAKW 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 164 SkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSALGPLALLPLPGEyRRSVVW---P--VKK 238
Cdd:PRK08849 159 V---IGADGANSQVRQLAGIGITAWDYRQHCMLINVETEQPQQDITWQQFTPSGPRSFLPLCGN-QGSLVWydsPkrIKQ 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 239 --GTESEWLGDENDQHFLSALqqtyGDRagKFEKTGkrfSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRD 316
Cdd:PRK08849 235 lsAMNPEQLRSEILRHFPAEL----GEI--KVLQHG---SFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQGVNLGFKD 305

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 317 ADVLLRYLVNQLSASDDIgnpdnLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANY 396
Cdd:PRK08849 306 VDVLLAETEKQGVLNDAS-----FARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGPLKTQVLKY 380


                 ....
gi 447110113 397 AMGL 400
Cdd:PRK08849 381 ALGM 384
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 5-390 6.84e-34

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 131.03  E-value: 6.84e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113    5 VIIVGGGMVGLSLSLMLAK----ANIAVKLLEAVKYPNYDDQNVAPYHSSFDARNTALSRRSVQIYQKLGLWDALQQHAT 80
Cdd:TIGR01989   3 VVIVGGGPVGLALAAALGNnpltKDLKVLLLDAVDNPKLKSRNYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   81 -PILQVHITEQGSFGKARLVAEQEKvESFGQVIENAWLGRVLLTQVRQQPL----IELIDGVQVTALTQDAE-----QVH 150
Cdd:TIGR01989  83 qPFGRMQVWDGCSLALIRFDRDNGK-EDMACIIENDNIQNSLYNRLQEYNGdnvkILNPARLISVTIPSKYPndnsnWVH 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  151 IEAQRGDELLKLESkllIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHEN-VGFERFSALGPLALLPLPGEYr 229
Cdd:TIGR01989 162 ITLSDGQVLYTKLL---IGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENdVAWQRFLPTGPIALLPLPDNN- 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  230 RSVVWPVKKgTESEWLGDENDQHFL----SALQQTYGD---------------RAGKFEKTGK----------------- 273
Cdd:TIGR01989 238 STLVWSTSP-EEALRLLSLPPEDFVdalnAAFDLGYSDhpysylldyameklnEDIGFRTEGSkscfqvpprvigvvdks 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  274 RFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVLLRYLVNQLSASDDIGNPDNLLAYEQARLSDQQR 353
Cdd:TIGR01989 317 RAAFPLGLGHADEYVTKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVV 396

                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 447110113  354 VIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVK 390
Cdd:TIGR01989 397 LLGLVDKLHKLYATDFPPVVALRTFGLNLTNYIGPLK 433
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 5-399 3.25e-29

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 116.95  E-value: 3.25e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLLEA--VKYPNYDDqnvapyhssfDARNTALSRRSVQIYQKLGLWDALQQHATPI 82
Cdd:PRK06617   4 TVILGCGLSGMLTALSFAQKGIKTTIFESksVKSPEFFK----------DIRTTALTPHSKNFLFSIDIWEELEKFVAEM 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  83 LQVHITEQGSFGKARLVAEQEKVesFGQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQrgdeLLKL 162
Cdd:PRK06617  74 QDIYVVDNKASEILDLRNDADAV--LGYVVKNSDFKKILLSKITNNPLITLIDNNQYQEVISHNDYSIIKFD----DKQI 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 163 ESKLLIAADGRDSFCRQAIGVGvDVHDYDQVAIVTTVQTSKPHENVGFERFSALGPLALLPLPGEYRRSVVWPVKKGTES 242
Cdd:PRK06617 148 KCNLLIICDGANSKVRSHYFAN-EIEKPYQTALTFNIKHEKPHENCAMEHFLPLGPFALLPLKDQYASSVIWSTSSDQAA 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 243 EWLGDENDQ-HFLSalQQTYGDRAGKFEKTGKRFSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVLl 321
Cdd:PRK06617 227 LIVNLPVEEvRFLT--QRNAGNSLGKITIDSEISSFPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEIL- 303

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447110113 322 rylvnqlsaSDDIGNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQNPLLKLIRNTGLIAFDVIPGVKPLVANYAMG 399
Cdd:PRK06617 304 ---------SMIVSNNGTLQEYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYAMG 372
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 4-357 1.17e-21

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 95.08  E-value: 1.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113    4 QVIIVGGGMVGLSLSLMLAKANIAVKLLEAvkypnYDDQNVAPyhssfdaRNTALSRRSVQIYQKLGLWDALQQHATPIL 83
Cdd:pfam01494   3 DVLIVGGGPAGLMLALLLARAGVRVVLVER-----HATTSVLP-------RAHGLNQRTMELLRQAGLEDRILAEGVPHE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   84 QVHITEQGSFGKARLVAEQ--EKVESFGQVIenawLGRVLLTQVRQQPLiELIDGVQVTALTQDAEQVHIEA--QRGDEL 159
Cdd:pfam01494  71 GMGLAFYNTRRRADLDFLTspPRVTVYPQTE----LEPILVEHAEARGA-QVRFGTEVLSLEQDGDGVTAVVrdRRDGEE 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  160 LKLESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKP-------HENVGFERFSALGPLALLPLPGEYRRSV 232
Cdd:pfam01494 146 YTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDlsdpverAFVHYLIYAPHSRGFMVGPWRSAGRERY 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  233 VWPVKKGTE-SEWLGDENDQHFLSALQQTYGDRAGKFEKTGKRfSYPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFN 311
Cdd:pfam01494 226 YVQVPWDEEvEERPEEFTDEELKQRLRSIVGIDLALVEILWKS-IWGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLN 304

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 447110113  312 LCLRDADVLLRYL--VNQLSASDDIgnpdnLLAYEQARLSDQQRVIKF 357
Cdd:pfam01494 305 TAIQDAFNLAWKLaaVLRGQAGESL-----LDTYSAERLPVAWAVVDF 347
PRK06126 PRK06126
hypothetical protein; Provisional
 1-347 1.39e-15

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 78.50  E-value: 1.39e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvapyhsSFDARNTALSRRSVQIYQKLGLWDALQQHAT 80
Cdd:PRK06126   6 SETPVLIVGGGPVGLALALDLGRRGVDSILVERKDGT------------AFNPKANTTSARSMEHFRRLGIADEVRSAGL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  81 PI----LQVHIT-----EQGSFGKARLVAEQEKVESF---------GQVIENAWLGRVLLTQVRQQPLIELIDGVQVTAL 142
Cdd:PRK06126  74 PVdyptDIAYFTrltgyELARFRLPSAREAITPVGGPdgswpspelPHRIPQKYLEPILLEHAAAQPGVTLRYGHRLTDF 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 143 TQDAEQV--HIEAQRGDELLKLESKLLIAADGRDSFCRQAIG---VGVDVHDYDQVaivTTVQTSKPHENVGFERfsalg 217
Cdd:PRK06126 154 EQDADGVtaTVEDLDGGESLTIRADYLVGCDGARSAVRRSLGisyEGTSGLQRDLS---IYIRAPGLAALVGHDP----- 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 218 pLALLPLPGEYRRSVVWPVkkgtesewlgDENDQHFLSALqqtygdRAGKFEKT--------------GKRFSYPL---- 279
Cdd:PRK06126 226 -AWMYWLFNPDRRGVLVAI----------DGRDEWLFHQL------RGGEDEFTiddvdarafvrrgvGEDIDYEVlsvv 288

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447110113 280 ----SQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDAdvllrylVN---QLSAS-DDIGNPDNLLAYEQAR 347
Cdd:PRK06126 289 pwtgRRLVADSYRRGRVFLAGDAAHLFTPTGGYGMNTGIGDA-------VNlawKLAAVlNGWAGPALLDSYEAER 357
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
4-317 4.17e-11

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 64.54  E-value: 4.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   4 QVIIVGGGMVGLSLSLMLAKANIAVKLLE----AVKYPnyddqnvapyhssfdaRNTALSRRSVQIYQKLGLWDALQQHA 79
Cdd:PRK06183  12 DVVIVGAGPVGLTLANLLGQYGVRVLVLErwptLYDLP----------------RAVGIDDEALRVLQAIGLADEVLPHT 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  80 TP-------------ILQVHITEQGSFGKARlvaeqekVESFGQvienAWLGRVLLTQVRQQPLIELIDGVQVTALTQDA 146
Cdd:PRK06183  76 TPnhgmrfldakgrcLAEIARPSTGEFGWPR-------RNAFHQ----PLLEAVLRAGLARFPHVRVRFGHEVTALTQDD 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 147 EQVHIEAQRGDELLKLESKL-LIAADGRDSFCRQAIGVG------------VDV---HDYDQVAIVT--------TVQTS 202
Cdd:PRK06183 145 DGVTVTLTDADGQRETVRARyVVGCDGANSFVRRTLGVPfedltfperwlvVDVliaNDPLGGPHTYqycdparpYTSVR 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 203 KPHenvGFERFsalgplallplpgEYRrsvvwpVKKG-TESEWLGDENDQHFLSAlqqtYGDRAGKFEKTGKRfSYPLSQ 281
Cdd:PRK06183 225 LPH---GRRRW-------------EFM------LLPGeTEEQLASPENVWRLLAP----WGPTPDDAELIRHA-VYTFHA 277

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 447110113 282 VLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDA 317
Cdd:PRK06183 278 RVADRWRSGRVLLAGDAAHLMPPFAGQGMNSGIRDA 313
PRK06475 PRK06475
FAD-binding protein;
1-320 6.88e-11

FAD-binding protein;


Pssm-ID: 180582 [Multi-domain]  Cd Length: 400  Bit Score: 63.30  E-value: 6.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPNYDDQNV--APYHSSFDARNTALSRRSVQ--IYQKLGLWDALQ 76
Cdd:PRK06475   1 TRGSPLIAGAGVAGLSAALELAARGWAVTIIEKAQELSEVGAGLqlAPNAMRHLERLGVADRLSGTgvTPKALYLMDGRK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  77 qhATPILQVHITEqgsfgkarlVAEQEKVESFgQVIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQDAEQVHIEAQRG 156
Cdd:PRK06475  81 --ARPLLAMQLGD---------LARKRWHHPY-IVCHRADLQSALLDACRNNPGIEIKLGAEMTSQRQTGNSITATIIRT 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 157 DELLKLESKLLIAADGRDSFCRQaigvgvdvhdydqvaivttvqtSKPHENVGFERFSALGPLALLPLPGEYRRSVVWPV 236
Cdd:PRK06475 149 NSVETVSAAYLIACDGVWSMLRA----------------------KAGFSKARFSGHIAWRTTLAADALPASFLSAMPEH 206

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 237 KkgTESEWLGDENdqHFLSALQQ----------TYGDRAGK-FEKTGKR---------FSYPLSQVLAH----------- 285
Cdd:PRK06475 207 K--AVSAWLGNKA--HFIAYPVKggkffnfvaiTGGENPGEvWSKTGDKahlksiyadWNKPVLQILAAidewtywplfe 282

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 447110113 286 ---KQAVG--RVILMGNAAHTIHPVAGQGFNLCLRDADVL 320
Cdd:PRK06475 283 madAQFVGpdRTIFLGDASHAVTPFAAQGAAMAIEDAAAL 322
PRK08244 PRK08244
monooxygenase;
1-317 8.91e-11

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 63.22  E-value: 8.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvAPYhssfdARNTALSRRSVQIYQKLGLWDALQQHAT 80
Cdd:PRK08244   1 MKYEVIIIGGGPVGLMLASELALAGVKTCVIERLKET-------VPY-----SKALTLHPRTLEILDMRGLLERFLEKGR 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  81 PILQVHI---------TEQGSFGKARLVAEQEKVEsfgQVIENaW---LGrvlltqvrqqplIELIDGVQVTALTQDAEQ 148
Cdd:PRK08244  69 KLPSGHFagldtrldfSALDTSSNYTLFLPQAETE---KVLEE-HarsLG------------VEIFRGAEVLAVRQDGDG 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 149 VHIEAQRGDELLKLESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQTSKPHENVGFERFSALGPLALLPLPGE- 227
Cdd:PRK08244 133 VEVVVRGPDGLRTLTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVLSLCTREGGVMIVPLSGGi 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 228 YRRSVVWPVKKGTESEWLGDENDqhFLSALQQTYGDRAGKFE-KTGKRFSYPLSQvlAHKQAVGRVILMGNAAHtIH-PV 305
Cdd:PRK08244 213 YRVLIIDPERPQVPKDEPVTLEE--LKTSLIRICGTDFGLNDpVWMSRFGNATRQ--AERYRSGRIFLAGDAAH-IHfPA 287

                        330
                 ....*....|..
gi 447110113 306 AGQGFNLCLRDA 317
Cdd:PRK08244 288 GGQGLNVGLQDA 299
PRK06185 PRK06185
FAD-dependent oxidoreductase;
1-325 3.01e-10

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 61.41  E-value: 3.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAvkypnyddqnvapyHSSF--DARNTALSRRSVQIYQKLGLWDALQQH 78
Cdd:PRK06185   5 ETTDCCIVGGGPAGMMLGLLLARAGVDVTVLEK--------------HADFlrDFRGDTVHPSTLELMDELGLLERFLEL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  79 AtpilqvHITeqgsfgkarlvAEQEKVESFGQVIENAWLGRV------------------LLTQVRQQPLIELIDGVQVT 140
Cdd:PRK06185  71 P------HQK-----------VRTLRFEIGGRTVTLADFSRLptpypyiammpqwdfldfLAEEASAYPNFTLRMGAEVT 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 141 ALTQDAEQVH-IEAQRGDELLKLESKLLIAADGRDSFCRQAigVGVDVHDYDQVAIVTTVQTSKPHE--NVGFERFSALG 217
Cdd:PRK06185 134 GLIEEGGRVTgVRARTPDGPGEIRADLVVGADGRHSRVRAL--AGLEVREFGAPMDVLWFRLPREPDdpESLMGRFGPGQ 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 218 PLALLPLPGEYRrsVVWPVKKGTESEW--LGDENDQHFLSALQQTYGDRAGKFEKtgkrfsypLSQVLAHKQAVGRV--- 292
Cdd:PRK06185 212 GLIMIDRGDYWQ--CGYVIPKGGYAALraAGLEAFRERVAELAPELADRVAELKS--------WDDVKLLDVRVDRLrrw 281

                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 447110113 293 -----ILMGNAAHTIHPVAGQGFNLCLRDADVLLRYLV 325
Cdd:PRK06185 282 hrpglLCIGDAAHAMSPVGGVGINLAIQDAVAAANILA 319
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
10-346 1.55e-09

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 58.44  E-value: 1.55e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  10 GGMVGLSLSLMLAKANIAVKLLEAVKYPnyddqnvapyhssfDARNT--ALSRRSVQIYQKLGLWDALQQHATpilqvhi 87
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFP--------------GDKICggGLLPRALEELEPLGLDEPLERPVR------- 59

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  88 teqgsfgKARLVAEQEKVESFGQVIENAW------LGRVLLTQVRQQPlIELIDGVQVTALTQDAEQVHIEAQRGDellK 161
Cdd:COG0644   60 -------GARFYSPGGKSVELPPGRGGGYvvdrarFDRWLAEQAEEAG-AEVRTGTRVTDVLRDDGRVVVRTGDGE---E 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 162 LESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIvtTVQTskphenvgferfsalgplallplpgEYRRSVVWPVKKGTE 241
Cdd:COG0644  129 IRADYVVDADGARSLLARKLGLKRRSDEPQDYAL--AIKE-------------------------HWELPPLEGVDPGAV 181

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 242 SEWLGDENDQHFlsalqqtygdrAGKFEKTGKRFS--YPLSQVLAhKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADV 319
Cdd:COG0644  182 EFFFGEGAPGGY-----------GWVFPLGDGRVSvgIPLGGPRP-RLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRL 249

                        330       340
                 ....*....|....*....|....*..
gi 447110113 320 LLRYLVNQLSASDDigNPDNLLAYEQA 346
Cdd:COG0644  250 AAEAIAEALEGGDF--SAEALAEYERR 274
PRK06184 PRK06184
hypothetical protein; Provisional
 5-348 1.80e-08

hypothetical protein; Provisional


Pssm-ID: 235728 [Multi-domain]  Cd Length: 502  Bit Score: 56.15  E-value: 1.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLLEavkypnyddQNVAPYHSSfdaRNTALSRRSVQIYQKLGLWDALQQHATPILQ 84
Cdd:PRK06184   6 VLIVGAGPTGLTLAIELARRGVSFRLIE---------KAPEPFPGS---RGKGIQPRTQEVFDDLGVLDRVVAAGGLYPP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  85 VHIT-EQGSFGKARLVAEQEKVEsfGQVIENAWLGRVLLTQ-VRQQPLIELidGVQV------TALTQDAEQVHIEAQRG 156
Cdd:PRK06184  74 MRIYrDDGSVAESDMFAHLEPTP--DEPYPLPLMVPQWRTErILRERLAEL--GHRVefgcelVGFEQDADGVTARVAGP 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 157 DELLKLESKLLIAADGRDSFCRQAIGVG-VDVHDYDQVAIVTTVQTSK---------PHENVGFerfsalgplallplpg 226
Cdd:PRK06184 150 AGEETVRARYLVGADGGRSFVRKALGIGfPGETLGIDRMLVADVSLTGldrdawhqwPDGDMGM---------------- 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 227 eyrrSVVWPVKkGTES-EW-----LGDENDQHfLSALQQTYGDRAGKfekTGKRFSYP--LSQV-----LAHKQAVGRVI 293
Cdd:PRK06184 214 ----IALCPLP-GTDLfQIqaplpPGGEPDLS-ADGLTALLAERTGR---TDIRLHSVtwASAFrmnarLADRYRVGRVF 284

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 447110113 294 LMGNAAHtIHPVAG-QGFNLCLRDAdvllrY-LVNQLSASDDiGNPDNLL-AYEQARL 348
Cdd:PRK06184 285 LAGDAAH-VHPPAGgQGLNTSVQDA-----YnLGWKLAAVLA-GAPEALLdTYEEERR 335
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
1-180 1.77e-07

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 52.73  E-value: 1.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEAVKY-----------PNyddqnvaPYHSsFDARNTALSRRSVQIY-QK 68
Cdd:PRK08163   3 KVTPVLIVGGGIGGLAAALALARQGIKVKLLEQAAEigeigagiqlgPN-------AFSA-LDALGVGEAARQRAVFtDH 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  69 LGLWDALQQHatpilQVHITEQGSFGKARlvaeqekvesFGQ---VIENAWLGRVLLTQVRQQPLIELIDGVQVTALTQD 145
Cdd:PRK08163  75 LTMMDAVDAE-----EVVRIPTGQAFRAR----------FGNpyaVIHRADIHLSLLEAVLDHPLVEFRTSTHVVGIEQD 139

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 447110113 146 AEQVHIEAQRGDellKLESKLLIAADGRDSFCRQA 180
Cdd:PRK08163 140 GDGVTVFDQQGN---RWTGDALIGCDGVKSVVRQS 171
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 5-183 2.59e-07

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 52.56  E-value: 2.59e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAvkypnyDDqnvapyHSSFDARNTALSRRSVQIYQKLGLWDalqqhatPILQ 84
Cdd:PRK08132  26 VVVVGAGPVGLALAIDLAQQGVPVVLLDD------DD------TLSTGSRAICFAKRSLEIFDRLGCGE-------RMVD 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  85 VHITEQG--SFGKARLVAE------------------QEKVESFgqvienawlgrvLLTQVRQQPLIELIDGVQVTALTQ 144
Cdd:PRK08132  87 KGVSWNVgkVFLRDEEVYRfdllpepghrrpafinlqQYYVEGY------------LVERAQALPNIDLRWKNKVTGLEQ 154

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 447110113 145 DAEQVHIEAQRGDELLKLESKLLIAADGRDSFCRQAIGV 183
Cdd:PRK08132 155 HDDGVTLTVETPDGPYTLEADWVIACDGARSPLREMLGL 193
PRK07045 PRK07045
putative monooxygenase; Reviewed
 243-357 4.38e-07

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 51.45  E-value: 4.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 243 EWLGDENDQHFLSALQQTYGDRAGKFEKT---GKRFS-YPLSQVLAHKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDAD 318
Cdd:PRK07045 234 GYLADTTRTKLLARLNEFVGDESADAMAAigaGTAFPlIPLGRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAG 313

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 447110113 319 VLLRYLvnQLSASDDIGNPDNLLAYEQARLSDQQRVIKF 357
Cdd:PRK07045 314 ELGACL--DLHLSGQIALADALERFERIRRPVNEAVISY 350
PRK06834 PRK06834
hypothetical protein; Provisional
 1-341 1.54e-06

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 50.02  E-value: 1.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   1 MQQQVIIVGGGMVGLSLSLMLAKANIAVKLLEavKYPNyddQNVApyhssfDARNTALSRRSVQIYQKLGLWDALqqhat 80
Cdd:PRK06834   2 TEHAVVIAGGGPTGLMLAGELALAGVDVAIVE--RRPN---QELV------GSRAGGLHARTLEVLDQRGIADRF----- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  81 pILQVHITEQGSFGKARL-VAEQEKVESFGQVIENAWLGRVLLTQVRQQPlIELIDGVQVTALTQDAEQVHIEAQRGdel 159
Cdd:PRK06834  66 -LAQGQVAQVTGFAATRLdISDFPTRHNYGLALWQNHIERILAEWVGELG-VPIYRGREVTGFAQDDTGVDVELSDG--- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 160 LKLESKLLIAADGRDSFCRQAIGVGVDVHDYDQVAIVTTVQ-TSKP-----HENVGFERFSALgplallplpgEY----R 229
Cdd:PRK06834 141 RTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEmTEEPewgvhRDALGIHAFGRL----------EDegpvR 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 230 RSVVWPVKKGTESEWLGDendqhfLS-ALQQTYGDRAGKFEKTG-KRFSYPLSQVLAHKQavGRVILMGNAAHTIHPVAG 307
Cdd:PRK06834 211 VMVTEKQVGATGEPTLDD------LReALIAVYGTDYGIHSPTWiSRFTDMARQAASYRD--GRVLLAGDAAHVHSPVGG 282

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 447110113 308 QGFNLCLRDADVL---LRYLVNQLSasddignPDNLL 341
Cdd:PRK06834 283 QGLNTGVQDAVNLgwkLAQVVKGTS-------PESLL 312
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
5-119 1.70e-06

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 49.52  E-value: 1.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAvkypnyddqNVAPYHSSF--------------DARNTALSRRSVQIYQKL- 69
Cdd:COG0665    5 VVVIGGGIAGLSTAYHLARRGLDVTVLER---------GRPGSGASGrnagqlrpglaalaDRALVRLAREALDLWRELa 75

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 447110113  70 ---GLwdALQQHATPILQVHITEQgsfGKARLVAEQEKVESFGqvIENAWLGR 119
Cdd:COG0665   76 aelGI--DCDFRRTGVLYLARTEA---ELAALRAEAEALRALG--LPVELLDA 121
PRK06847 PRK06847
hypothetical protein; Provisional
 3-181 2.02e-06

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 49.49  E-value: 2.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113   3 QQVIIVGGGMVGLSLSLMLAKANIAVKLLEAvkypnydDQNVAPYHSSFdarntALSRRSVQIYQKLGLWDALQQHATPI 82
Cdd:PRK06847   5 KKVLIVGGGIGGLSAAIALRRAGIAVDLVEI-------DPEWRVYGAGI-----TLQGNALRALRELGVLDECLEAGFGF 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113  83 LQVHI-TEQGSfgkarLVAEQEKVESFGQVIENAW------LGRVLLTQVRQQPL-IELidGVQVTALTQDAEQVHI--- 151
Cdd:PRK06847  73 DGVDLfDPDGT-----LLAELPTPRLAGDDLPGGGgimrpaLARILADAARAAGAdVRL--GTTVTAIEQDDDGVTVtfs 145

                        170       180       190
                 ....*....|....*....|....*....|..
gi 447110113 152 --EAQRGDellkleskLLIAADGRDSFCRQAI 181
Cdd:PRK06847 146 dgTTGRYD--------LVVGADGLYSKVRSLV 169
PRK06753 PRK06753
hypothetical protein; Provisional
 290-378 3.78e-05

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 45.45  E-value: 3.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113 290 GRVILMGNAAHTIHPVAGQGFNLCLRDADVllryLVNQLSASDdigNPDNLLAYEQARLSDQQRVIKFCDTVVRGFSNQN 369
Cdd:PRK06753 270 GRIVLLGDAAHATTPNMGQGAGQAMEDAIV----LANCLNAYD---FEKALQRYDKIRVKHTAKVIKRSRKIGKIAQIES 342


                 ....*....
gi 447110113 370 PLLKLIRNT 378
Cdd:PRK06753 343 KLLVALRNR 351
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 5-91 2.39e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 42.77  E-value: 2.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447110113    5 VIIVGGGMVGLSLSLMLAKANIAVKLLEAvkypnyddQNVAPYHSSFdaRNTALSRRSVQIYQKLGLWDaLQQHATPILQ 84
Cdd:pfam01266   2 VVVIGGGIVGLSTAYELARRGLSVTLLER--------GDDPGSGASG--RNAGLIHPGLRYLEPSELAR-LALEALDLWE 70


                  ....*..
gi 447110113   85 VHITEQG 91
Cdd:pfam01266  71 ELEEELG 77
PRK07538 PRK07538
hypothetical protein; Provisional
 290-348 3.50e-04

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 42.58  E-value: 3.50e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 447110113 290 GRVILMGNAAHTIHPVAGQGFNLCLRDAdvllRYLVNQLSASDDIgnPDNLLAYEQARL 348
Cdd:PRK07538 297 GRVTLLGDAAHPMYPVGSNGASQAILDA----RALADALAAHGDP--EAALAAYEAERR 349
PRK08255 PRK08255
bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;
285-347 4.52e-04

bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;


Pssm-ID: 236203 [Multi-domain]  Cd Length: 765  Bit Score: 42.62  E-value: 4.52e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447110113 285 HKQAVGRVILMGNAAHTIHPVAGQGFNLCLRDADVLLRYLvnqlsASDDIGNPDNLLAYEQAR 347
Cdd:PRK08255 264 HWNRRVPVVLMGDAAHTAHFSIGSGTKLALEDAIELARCL-----HEHPGDLPAALAAYEEER 321
PRK07538 PRK07538
hypothetical protein; Provisional
 4-34 7.65e-04

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 41.42  E-value: 7.65e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 447110113   4 QVIIVGGGMVGLSLSLMLAKANIAVKLLEAV 34
Cdd:PRK07538   2 KVLIAGGGIGGLTLALTLHQRGIEVVVFEAA 32
trkA PRK09496
Trk system potassium transporter TrkA;
2-32 5.28e-03

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 38.95  E-value: 5.28e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 447110113   2 QQQVIIVGGGMVGLSLSLMLAKANIAVKLLE 32
Cdd:PRK09496 231 VKRVMIVGGGNIGYYLAKLLEKEGYSVKLIE 261
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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