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Conserved domains on  [gi|447130667|ref|WP_001207923|]
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MULTISPECIES: nitrate/nitrite transporter NarU [Escherichia]

Protein Classification

NarK family nitrate/nitrite MFS transporter( domain architecture ID 10014945)

NarK family nitrate/nitrite MFS transporter is a Major Facilitator Superfamily (MFS) transporter that facilitates nitrate uptake, nitrite uptake and nitrite export across the cytoplasmic membrane, and may function as a nitrate/H(+) and nitrite/H(+) channel

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK15034 PRK15034
nitrate/nitrite transport protein NarU; Provisional
1-462 0e+00

nitrate/nitrite transport protein NarU; Provisional


:

Pssm-ID: 184994 [Multi-domain]  Cd Length: 462  Bit Score: 822.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667   1 MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTEQLFLLTALPS 80
Cdd:PRK15034   1 MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  81 VSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK 160
Cdd:PRK15034  81 VSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 161 QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRA 240
Cdd:PRK15034 161 QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 241 SIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTL 320
Cdd:PRK15034 241 SIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 321 INFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQAQREAVTET 400
Cdd:PRK15034 321 INFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQAQREAVTET 400
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447130667 401 AAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRKFSQK 462
Cdd:PRK15034 401 AAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRKFSQK 462
 
Name Accession Description Interval E-value
PRK15034 PRK15034
nitrate/nitrite transport protein NarU; Provisional
1-462 0e+00

nitrate/nitrite transport protein NarU; Provisional


Pssm-ID: 184994 [Multi-domain]  Cd Length: 462  Bit Score: 822.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667   1 MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTEQLFLLTALPS 80
Cdd:PRK15034   1 MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  81 VSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK 160
Cdd:PRK15034  81 VSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 161 QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRA 240
Cdd:PRK15034 161 QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 241 SIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTL 320
Cdd:PRK15034 241 SIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 321 INFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQAQREAVTET 400
Cdd:PRK15034 321 INFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQAQREAVTET 400
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447130667 401 AAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRKFSQK 462
Cdd:PRK15034 401 AAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRKFSQK 462
MFS_NRT2_like cd17341
Plant Nitrate transporter NRT2 family and Bacterial Nitrate/Nitrite transporters of the Major ...
36-452 3.42e-92

Plant Nitrate transporter NRT2 family and Bacterial Nitrate/Nitrite transporters of the Major Facilitator Superfamily; This family is composed of plant NRT2 family high-affinity nitrate transporters as well as nitrate and nitrite transporters from bacteria including Bacillus subtilis nitrate transporter NasA and nitrite extrusion protein NarK, Staphylococcus aureus NarT, Synechococcus sp. nitrate permease NapA, Mycobacterium tuberculosis NarK2 and nitrite extrusion protein NarU. NRT2 family proteins are involved in the uptake of nitrate by plant roots from the soil through the high-affinity transport system (HATS). There are seven Arabidopsis thaliana NRT2 proteins, called AtNRT2:1 to AtNRT2:7. The NRT2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.


Pssm-ID: 340899 [Multi-domain]  Cd Length: 384  Bit Score: 284.53  E-value: 3.42e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  36 LWISVSCLLLAFCVWMLFSAVTVNLNKIgFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCV 115
Cdd:cd17341    1 LHLSWLSFFLGFMVWFLFAPLGPVIRDD-LGLSTSQIGLLVAIPVLAGALLRLPYGFLCDRFGGRRVFIASLLLLLIPLL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 116 WLGIAVQnpntPFGIFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFVPVFafl 195
Cdd:cd17341   80 ALALAVS----SYWGLLVLGFLLGFAGANFASGQPWASFWFPKEKIGGAAGGIAGAGNMGVAVSQLLAPLIAGAIVF--- 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 196 gvngvpqaDGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRASI----ADQLPVLQRLHLWLLSLLYLATFGSFIGF 271
Cdd:cd17341  153 --------DGGFVGWRNAFFVPGILLAIAAVLVLLFGDDLPTGKASAleflKVQLAVLKNYRTWILSLLYGVTFGSFVGF 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 272 SAGFAMLAKTQF--PDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPgTGSGNFIAFY 349
Cdd:cd17341  225 SNVLPTYFKTRFglPLVTAGILAALFPLAGALARPAGGWLSDRFGGRRRLWWLFIVMTIGAALLSLSLP-TSGTNLVLFL 303
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 350 AVFMGLFLTAGLGSGSTFQMIAVIFRQitiyrvkmkggsdeqaqreavtETAAALGFISAIGAVGGFFIPQAFGMSLNMT 429
Cdd:cd17341  304 ALFVALGLGAGAGNGSVFRMVPFIFRR----------------------ELGAVTGLVGAIGGLGGFFLPLLFGSSALMT 361
                        410       420
                 ....*....|....*....|...
gi 447130667 430 GSPVGAMKVFLIFYIVCVLLTWL 452
Cdd:cd17341  362 GSGVGAFSLFGVLAVACTLLVWL 384
2A0108 TIGR00886
nitrite extrusion protein (nitrite facilitator); [Transport and binding proteins, Anions]
34-415 6.89e-85

nitrite extrusion protein (nitrite facilitator); [Transport and binding proteins, Anions]


Pssm-ID: 273322 [Multi-domain]  Cd Length: 354  Bit Score: 264.55  E-value: 6.89e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667   34 RNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIP 113
Cdd:TIGR00886   1 RNLFFSWFGFFLSFLVWFAFSPLAVFLIKDDLGLSTAQLGNLVAVPVLAGAVLRIILGFLVDIFGPRYTTALSLLLLAIP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  114 CVWLGIAVQNPNTpfgiFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFvpVFA 193
Cdd:TIGR00886  81 CLWAGLAVQSYSV----LLLIRLFIGIAGGSFASCMPWISFFFPKKIQGTALGLAAGWGNMGGGVAQFVMPPIIG--SLI 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  194 FLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSA 273
Cdd:TIGR00886 155 FGGGQPAHLAWGWAFVIVPAGILLLPALLIFFVGADTPPGKPATGKLSFKEALKVFGNRHTWILALLYSVTFGSFLGVSS 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  274 GFAMLAKTQFP--DVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTGSgnFIAFYAV 351
Cdd:TIGR00886 235 IFAMLFKDQFGlsKVQAGAYASLGGFLGSLARPAGGAISDRLGGARKLLMNFLGVAMGAFLVVLGLVSDGS--LAAFIVL 312
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447130667  352 FMGLFLTAGLGSGSTFQMIAVIFRQitiyrvkmkggsdeqaqreavtETAAALGFISAIGAVGG 415
Cdd:TIGR00886 313 FVALFFFAGAGNGSTFALVPHIFRR----------------------ATGAVSGLIGAIGNLGG 354
NarK COG2223
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism];
31-458 4.30e-70

Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism];


Pssm-ID: 441825 [Multi-domain]  Cd Length: 392  Bit Score: 227.46  E-value: 4.30e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  31 IARRNLWISVSCLLLAFCVWMLFSAVTVNLNKiGFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAIL 110
Cdd:COG2223    2 GRWRVLLLATLAFFLAFGVWYLWSVLAPPLAE-EFGLSAAQLGLLFAIPVLVGALLRIPLGFLVDRFGPRRVLLIGLLLL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 111 IIPCVWLGIAVqnpntPFGIFIVIALLCGF-AGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIfv 189
Cdd:COG2223   81 GIGLLLLALAV-----SYWLLLLLGLLLGIgGGGSFAVGIALVSKWFPPDRRGLALGLAAGGGNLGAAVAAFLAPLLI-- 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 190 pvfaflgvngvpqadgSVMSLANAAWIWVPLLAIATIAAWSGMNDI-----ASSRASIADQLPVLQRLHLWLLSLLYLAT 264
Cdd:COG2223  154 ----------------AAFGWRNAFLILGILLLVVAVLAWLFLRDPpagaaAAAKASLRDQLEALRDPRFWLLSLLYFGT 217
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 265 FGSFIGFSAGFAMLAKTQFPD--VNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLpgtgs 342
Cdd:COG2223  218 FGSFIGFSSWLPPYLVDQFGLsaATAGLLAALFALLGALGRPLGGWLSDRIGGRRVLLIVFALMALGLLLLALAL----- 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 343 GNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRqitiyrvkmkggsdeqaqreaVTETAAALGFISAIGAVGGFFIPQAF 422
Cdd:COG2223  293 GSLWLFLVLFLLLGLALGGGNGAVFALVPDIFP---------------------TKNAGAVYGLVGAAGGLGGFLGPLLF 351
                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 447130667 423 GMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRK 458
Cdd:COG2223  352 GALLDATGSYTAAFLVFAVLALVALVLTLLLYRRPR 387
MFS_1 pfam07690
Major Facilitator Superfamily;
42-373 2.08e-04

Major Facilitator Superfamily;


Pssm-ID: 429598 [Multi-domain]  Cd Length: 344  Bit Score: 43.18  E-value: 2.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667   42 CLLLAFCVWMLFSAVTVNLNKIGFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAv 121
Cdd:pfam07690   4 AAFLAALGRSLLGPALPLLLAEDLGISPTEIGLLLTLFSLGYALAQPLAGRLSDRFGRRRVLLIGLLLFALGLLLLLFA- 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  122 qnpnTPFGIFIVIALLCGFAGANFASSMGN-ISFFFPKAKQGSALGIngglgnlgVSVMQLVAPlVIFVPVFAFLGVNGV 200
Cdd:pfam07690  83 ----SSLWLLLVLRVLQGLGAGALFPAALAlIADWFPPEERGRALGL--------VSAGFGLGA-ALGPLLGGLLASLFG 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  201 PQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAK 280
Cdd:pfam07690 150 WRAAFLILAILSLLAAVLLLLPRPPPESKRPKPAEEARLSLIVAWKALLRDPVLWLLLALLLFGFAFFGLLTYLPLYQEV 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  281 TQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLpgtgsgnFIAFYAVFMGLFLTAG 360
Cdd:pfam07690 230 LGLSALLAGLLLGLGGLLGAIGRLLLGRLSDRLGRRRRLLLALLLLILAALGLLLLS-------LTLSSLWLLLALLLLG 302
                         330
                  ....*....|...
gi 447130667  361 LGSGSTFQMIAVI 373
Cdd:pfam07690 303 FGFGLVFPALNAL 315
 
Name Accession Description Interval E-value
PRK15034 PRK15034
nitrate/nitrite transport protein NarU; Provisional
1-462 0e+00

nitrate/nitrite transport protein NarU; Provisional


Pssm-ID: 184994 [Multi-domain]  Cd Length: 462  Bit Score: 822.98  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667   1 MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTEQLFLLTALPS 80
Cdd:PRK15034   1 MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  81 VSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK 160
Cdd:PRK15034  81 VSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 161 QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRA 240
Cdd:PRK15034 161 QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 241 SIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTL 320
Cdd:PRK15034 241 SIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 321 INFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQAQREAVTET 400
Cdd:PRK15034 321 INFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQAQREAVTET 400
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447130667 401 AAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRKFSQK 462
Cdd:PRK15034 401 AAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRKFSQK 462
MFS_NRT2_like cd17341
Plant Nitrate transporter NRT2 family and Bacterial Nitrate/Nitrite transporters of the Major ...
36-452 3.42e-92

Plant Nitrate transporter NRT2 family and Bacterial Nitrate/Nitrite transporters of the Major Facilitator Superfamily; This family is composed of plant NRT2 family high-affinity nitrate transporters as well as nitrate and nitrite transporters from bacteria including Bacillus subtilis nitrate transporter NasA and nitrite extrusion protein NarK, Staphylococcus aureus NarT, Synechococcus sp. nitrate permease NapA, Mycobacterium tuberculosis NarK2 and nitrite extrusion protein NarU. NRT2 family proteins are involved in the uptake of nitrate by plant roots from the soil through the high-affinity transport system (HATS). There are seven Arabidopsis thaliana NRT2 proteins, called AtNRT2:1 to AtNRT2:7. The NRT2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.


Pssm-ID: 340899 [Multi-domain]  Cd Length: 384  Bit Score: 284.53  E-value: 3.42e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  36 LWISVSCLLLAFCVWMLFSAVTVNLNKIgFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCV 115
Cdd:cd17341    1 LHLSWLSFFLGFMVWFLFAPLGPVIRDD-LGLSTSQIGLLVAIPVLAGALLRLPYGFLCDRFGGRRVFIASLLLLLIPLL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 116 WLGIAVQnpntPFGIFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFVPVFafl 195
Cdd:cd17341   80 ALALAVS----SYWGLLVLGFLLGFAGANFASGQPWASFWFPKEKIGGAAGGIAGAGNMGVAVSQLLAPLIAGAIVF--- 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 196 gvngvpqaDGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRASI----ADQLPVLQRLHLWLLSLLYLATFGSFIGF 271
Cdd:cd17341  153 --------DGGFVGWRNAFFVPGILLAIAAVLVLLFGDDLPTGKASAleflKVQLAVLKNYRTWILSLLYGVTFGSFVGF 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 272 SAGFAMLAKTQF--PDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPgTGSGNFIAFY 349
Cdd:cd17341  225 SNVLPTYFKTRFglPLVTAGILAALFPLAGALARPAGGWLSDRFGGRRRLWWLFIVMTIGAALLSLSLP-TSGTNLVLFL 303
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 350 AVFMGLFLTAGLGSGSTFQMIAVIFRQitiyrvkmkggsdeqaqreavtETAAALGFISAIGAVGGFFIPQAFGMSLNMT 429
Cdd:cd17341  304 ALFVALGLGAGAGNGSVFRMVPFIFRR----------------------ELGAVTGLVGAIGGLGGFFLPLLFGSSALMT 361
                        410       420
                 ....*....|....*....|...
gi 447130667 430 GSPVGAMKVFLIFYIVCVLLTWL 452
Cdd:cd17341  362 GSGVGAFSLFGVLAVACTLLVWL 384
2A0108 TIGR00886
nitrite extrusion protein (nitrite facilitator); [Transport and binding proteins, Anions]
34-415 6.89e-85

nitrite extrusion protein (nitrite facilitator); [Transport and binding proteins, Anions]


Pssm-ID: 273322 [Multi-domain]  Cd Length: 354  Bit Score: 264.55  E-value: 6.89e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667   34 RNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIP 113
Cdd:TIGR00886   1 RNLFFSWFGFFLSFLVWFAFSPLAVFLIKDDLGLSTAQLGNLVAVPVLAGAVLRIILGFLVDIFGPRYTTALSLLLLAIP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  114 CVWLGIAVQNPNTpfgiFIVIALLCGFAGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFvpVFA 193
Cdd:TIGR00886  81 CLWAGLAVQSYSV----LLLIRLFIGIAGGSFASCMPWISFFFPKKIQGTALGLAAGWGNMGGGVAQFVMPPIIG--SLI 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  194 FLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSA 273
Cdd:TIGR00886 155 FGGGQPAHLAWGWAFVIVPAGILLLPALLIFFVGADTPPGKPATGKLSFKEALKVFGNRHTWILALLYSVTFGSFLGVSS 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  274 GFAMLAKTQFP--DVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTGSgnFIAFYAV 351
Cdd:TIGR00886 235 IFAMLFKDQFGlsKVQAGAYASLGGFLGSLARPAGGAISDRLGGARKLLMNFLGVAMGAFLVVLGLVSDGS--LAAFIVL 312
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447130667  352 FMGLFLTAGLGSGSTFQMIAVIFRQitiyrvkmkggsdeqaqreavtETAAALGFISAIGAVGG 415
Cdd:TIGR00886 313 FVALFFFAGAGNGSTFALVPHIFRR----------------------ATGAVSGLIGAIGNLGG 354
NarK COG2223
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism];
31-458 4.30e-70

Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism];


Pssm-ID: 441825 [Multi-domain]  Cd Length: 392  Bit Score: 227.46  E-value: 4.30e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  31 IARRNLWISVSCLLLAFCVWMLFSAVTVNLNKiGFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAIL 110
Cdd:COG2223    2 GRWRVLLLATLAFFLAFGVWYLWSVLAPPLAE-EFGLSAAQLGLLFAIPVLVGALLRIPLGFLVDRFGPRRVLLIGLLLL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 111 IIPCVWLGIAVqnpntPFGIFIVIALLCGF-AGANFASSMGNISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIfv 189
Cdd:COG2223   81 GIGLLLLALAV-----SYWLLLLLGLLLGIgGGGSFAVGIALVSKWFPPDRRGLALGLAAGGGNLGAAVAAFLAPLLI-- 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 190 pvfaflgvngvpqadgSVMSLANAAWIWVPLLAIATIAAWSGMNDI-----ASSRASIADQLPVLQRLHLWLLSLLYLAT 264
Cdd:COG2223  154 ----------------AAFGWRNAFLILGILLLVVAVLAWLFLRDPpagaaAAAKASLRDQLEALRDPRFWLLSLLYFGT 217
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 265 FGSFIGFSAGFAMLAKTQFPD--VNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLpgtgs 342
Cdd:COG2223  218 FGSFIGFSSWLPPYLVDQFGLsaATAGLLAALFALLGALGRPLGGWLSDRIGGRRVLLIVFALMALGLLLLALAL----- 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 343 GNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRqitiyrvkmkggsdeqaqreaVTETAAALGFISAIGAVGGFFIPQAF 422
Cdd:COG2223  293 GSLWLFLVLFLLLGLALGGGNGAVFALVPDIFP---------------------TKNAGAVYGLVGAAGGLGGFLGPLLF 351
                        410       420       430
                 ....*....|....*....|....*....|....*.
gi 447130667 423 GMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRK 458
Cdd:COG2223  352 GALLDATGSYTAAFLVFAVLALVALVLTLLLYRRPR 387
MFS cd06174
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse ...
40-451 3.57e-09

Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.


Pssm-ID: 349949 [Multi-domain]  Cd Length: 378  Bit Score: 58.21  E-value: 3.57e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  40 VSCLLLAFCVWMLFSAVTVNLNKIgFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGI 119
Cdd:cd06174    2 LLGFFLTGLARGLISPLLPALLQS-FGLSASQLGLLFALFSLGYALLQPLAGLLADRFGRRPVLLLGLLLFALGALLFAF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 120 AvqnpnTPFGIFIVIALLCGFAGANFASSMGN-ISFFFPKAKQGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVN 198
Cdd:cd06174   81 A-----PSFWLLLLGRFLLGLGSGLIDPAVLAlIADLFPERERGRALGLLQAFGSVGGILGPLLGGILASSLGFGWRAVF 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 199 GVPQADGSVMSLAnaAWIWVPLLAIATIAAwsgmNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAML 278
Cdd:cd06174  156 LIAAALALLAAIL--LLLVVPDPPESARAK----NEEASSKSVLKLLKRVLKNPGLWLLLLAIFLVNLAYYSFSTLLPLF 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 279 AKT--QFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTL-INFIFMAIFSALLFLtlpgtgSGNFIAFYAVFMGL 355
Cdd:cd06174  230 LLDlgGLSVAVAGLLLSLFGLAGALGSLLLGLLSDRLIGRKPLLlIGLLLMALGLALLLL------APSLLLLLLLLLLL 303
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 356 FLTAGLGSGSTFQMIAVIFRQitiyrvkmkggsdeqaqreavTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGA 435
Cdd:cd06174  304 GFGLGGLLPLSFALIAELFPP---------------------EIRGTAFGLLNTFGFLGGAIGPLLAGFLLAATFGLTGA 362
                        410
                 ....*....|....*.
gi 447130667 436 MKVFLIFYIVCVLLTW 451
Cdd:cd06174  363 FLVLAVLLLLAAILLL 378
UhpC COG2271
Sugar phosphate permease [Carbohydrate transport and metabolism];
33-458 8.40e-06

Sugar phosphate permease [Carbohydrate transport and metabolism];


Pssm-ID: 441872 [Multi-domain]  Cd Length: 363  Bit Score: 47.56  E-value: 8.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  33 RRNLWISVSCLLLAFCVWMLFSAVTVNLNKIG--FNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAIL 110
Cdd:COG2271    6 RYRWRILALLFLAYFLNYLDRSNLSVAAPPLQadLGLSAAQLGLLASAFFLGYALGQIPAGLLADRFGRRRVLAIGLLLW 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 111 IIPCVWLGIAvqnpnTPFGIFIVIALLCGFA-GANFASSMGNISFFFPKAKQGSAlgingglgnlgVSVMQLVAPL--VI 187
Cdd:COG2271   86 GLATLLFGFA-----TSFWQLLLLRFLLGLGeAGFFPAALKLIAEWFPPKERGRA-----------LGIFNAGGPLggAL 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 188 FVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMndiasSRASIADQLPVLqrlhlwllsllylatFGS 267
Cdd:COG2271  150 APPLLGWLLAAFGWRAAFLILGLPGLLLALLRFWLLALAYFLVYF-----ALYGFLTWLPTY---------------LVE 209
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 268 FIGFSAGFAMLaktqfpdvnilrLAFFGPFIGAIARSVGGAISDKFGGVRVTLInfIFMAIFSALLFLTLPGTGSGNFIA 347
Cdd:COG2271  210 VRGLSLAQAGL------------LLSLPFLAGIVGSLLGGWLSDRLGRRRKLVL--AIGLLLAALALLLLALLPSPALAI 275
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 348 FYAVFMGLFLTAGLGSGSTFQMiavifrqitiyrvkmkggsdEQAQREAVtetAAALGFISAIGAVGGFFIPQAFGMSLN 427
Cdd:COG2271  276 ALLFLAGFGLGGAFGLLWALAA--------------------ELFPKKAR---GTASGLVNTFGFLGGALGPLLVGYLLD 332
                        410       420       430
                 ....*....|....*....|....*....|.
gi 447130667 428 MTGsPVGAMKVFLIFYIVCVLLTWLVYGRRK 458
Cdd:COG2271  333 ATG-YQAAFLLLAALALLAALLALLLLRETR 362
AraJ COG2814
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
32-359 7.67e-05

Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];


Pssm-ID: 442063 [Multi-domain]  Cd Length: 348  Bit Score: 44.58  E-value: 7.67e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  32 ARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIG--FNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAI 109
Cdd:COG2814    5 PRRRWLALLALALGAFLSGLGIGIVLPALPLIAadLGASPAQAGLVVTAYLLGAALGAPLAGRLADRFGRRRVLLLGLLL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 110 LIIPCVWLGIAvqnpnTPFGIFIVIALLCGFA-GANFASSMGNISFFFPKAKQGSAlgingglgnlgVSVMQLVAPL--V 186
Cdd:COG2814   85 FALGSLLCALA-----PSLWLLLAARFLQGLGaGALFPAALALIADLVPPERRGRA-----------LGLLGAGLGLgpA 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 187 IFVPVFAFLGvngvpqadgSVMSLANAAWIWVPLLAIATIAAWSGM--NDIASSRASIADQLPVLQRLHLWLLSLLYLAT 264
Cdd:COG2814  149 LGPLLGGLLA---------DLFGWRWVFLVNAVLALLALLLLLRLLpeSRPAARARLRGSLRELLRRPRLLLLLLLAFLL 219
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 265 FGSFIGFSAGFAMLAKTQF--PDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTGS 342
Cdd:COG2814  220 GFGFFALFTYLPLYLQEVLglSASAAGLLLALFGLGGVLGALLAGRLADRFGRRRLLLIGLLLLALGLLLLALAGSLWLL 299
                        330
                 ....*....|....*..
gi 447130667 343 GNFIAFYAVFMGLFLTA 359
Cdd:COG2814  300 LLALFLLGFGFGLLFPL 316
MFS_1 pfam07690
Major Facilitator Superfamily;
42-373 2.08e-04

Major Facilitator Superfamily;


Pssm-ID: 429598 [Multi-domain]  Cd Length: 344  Bit Score: 43.18  E-value: 2.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667   42 CLLLAFCVWMLFSAVTVNLNKIGFNFTTEQLFLLTALPSVSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAv 121
Cdd:pfam07690   4 AAFLAALGRSLLGPALPLLLAEDLGISPTEIGLLLTLFSLGYALAQPLAGRLSDRFGRRRVLLIGLLLFALGLLLLLFA- 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  122 qnpnTPFGIFIVIALLCGFAGANFASSMGN-ISFFFPKAKQGSALGIngglgnlgVSVMQLVAPlVIFVPVFAFLGVNGV 200
Cdd:pfam07690  83 ----SSLWLLLVLRVLQGLGAGALFPAALAlIADWFPPEERGRALGL--------VSAGFGLGA-ALGPLLGGLLASLFG 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  201 PQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAK 280
Cdd:pfam07690 150 WRAAFLILAILSLLAAVLLLLPRPPPESKRPKPAEEARLSLIVAWKALLRDPVLWLLLALLLFGFAFFGLLTYLPLYQEV 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667  281 TQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLpgtgsgnFIAFYAVFMGLFLTAG 360
Cdd:pfam07690 230 LGLSALLAGLLLGLGGLLGAIGRLLLGRLSDRLGRRRRLLLALLLLILAALGLLLLS-------LTLSSLWLLLALLLLG 302
                         330
                  ....*....|...
gi 447130667  361 LGSGSTFQMIAVI 373
Cdd:pfam07690 303 FGFGLVFPALNAL 315
CynX COG2807
Cyanate permease [Inorganic ion transport and metabolism];
297-453 3.12e-03

Cyanate permease [Inorganic ion transport and metabolism];


Pssm-ID: 442057 [Multi-domain]  Cd Length: 399  Bit Score: 39.86  E-value: 3.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447130667 297 FIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLFLTLPGTgsgnFIAFYAVFMGLfltaglGSGSTFQMIAVIFRQ 376
Cdd:COG2807  261 LAGIPGSLLVPLLADRLGDRRPLLLLLGLLGLAGLLGLLLAPGS----LPWLWAVLLGL------GQGGLFPLALTLIGL 330
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447130667 377 ITiyrvkmkggsdeqaqrEAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLV 453
Cdd:COG2807  331 RA----------------RTPAEAAALSGMAQSVGYLLAALGPLLVGALHDATGSWTAALLLLAALAVLMLVAGLLA 391
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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