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Conserved domains on  [gi|447135288|ref|WP_001212544|]
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MULTISPECIES: WxL domain-containing protein [Bacillus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
WxL super family cl16366
WxL domain surface cell wall-binding; The WxL motif appears in two or three copies in these ...
42-199 4.84e-08

WxL domain surface cell wall-binding; The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.


The actual alignment was detected with superfamily member pfam13731:

Pssm-ID: 433439  Cd Length: 205  Bit Score: 51.20  E-value: 4.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447135288   42 GEHNITVTPVSNF--NAVTLSGETQVTHANPGVLTVTDATGSGNGWRINVKADQFKvsgdTKSNRTLPKGSLVLNSGGAT 119
Cdd:pfam13731  50 GTQKISSKDETYYalAQYGVKGSVSGNENRPNYVQVTDNRGTNAGWTLSVKQSQFK----TTGGKELTGATITFKNGTVA 125
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447135288  120 iTKVGGTSSPNLEFKTTNFIIDTDNQVTILSAKKDEGMGKYNVSFNDKSL----ALTLNPHSTYVENkagATSYESKLTY 195
Cdd:pfam13731 126 -SNSDPTSPAPTSSTITLILTTGGTATLVMTAAAGTGAGTWSVVFGDAETetndAVQLTVPAGTAKA---ATQYTTTLTW 201

                  ....
gi 447135288  196 SIVT 199
Cdd:pfam13731 202 TLSD 205
 
Name Accession Description Interval E-value
WxL pfam13731
WxL domain surface cell wall-binding; The WxL motif appears in two or three copies in these ...
42-199 4.84e-08

WxL domain surface cell wall-binding; The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.


Pssm-ID: 433439  Cd Length: 205  Bit Score: 51.20  E-value: 4.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447135288   42 GEHNITVTPVSNF--NAVTLSGETQVTHANPGVLTVTDATGSGNGWRINVKADQFKvsgdTKSNRTLPKGSLVLNSGGAT 119
Cdd:pfam13731  50 GTQKISSKDETYYalAQYGVKGSVSGNENRPNYVQVTDNRGTNAGWTLSVKQSQFK----TTGGKELTGATITFKNGTVA 125
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447135288  120 iTKVGGTSSPNLEFKTTNFIIDTDNQVTILSAKKDEGMGKYNVSFNDKSL----ALTLNPHSTYVENkagATSYESKLTY 195
Cdd:pfam13731 126 -SNSDPTSPAPTSSTITLILTTGGTATLVMTAAAGTGAGTWSVVFGDAETetndAVQLTVPAGTAKA---ATQYTTTLTW 201

                  ....
gi 447135288  196 SIVT 199
Cdd:pfam13731 202 TLSD 205
 
Name Accession Description Interval E-value
WxL pfam13731
WxL domain surface cell wall-binding; The WxL motif appears in two or three copies in these ...
42-199 4.84e-08

WxL domain surface cell wall-binding; The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.


Pssm-ID: 433439  Cd Length: 205  Bit Score: 51.20  E-value: 4.84e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447135288   42 GEHNITVTPVSNF--NAVTLSGETQVTHANPGVLTVTDATGSGNGWRINVKADQFKvsgdTKSNRTLPKGSLVLNSGGAT 119
Cdd:pfam13731  50 GTQKISSKDETYYalAQYGVKGSVSGNENRPNYVQVTDNRGTNAGWTLSVKQSQFK----TTGGKELTGATITFKNGTVA 125
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447135288  120 iTKVGGTSSPNLEFKTTNFIIDTDNQVTILSAKKDEGMGKYNVSFNDKSL----ALTLNPHSTYVENkagATSYESKLTY 195
Cdd:pfam13731 126 -SNSDPTSPAPTSSTITLILTTGGTATLVMTAAAGTGAGTWSVVFGDAETetndAVQLTVPAGTAKA---ATQYTTTLTW 201

                  ....
gi 447135288  196 SIVT 199
Cdd:pfam13731 202 TLSD 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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