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Conserved domains on  [gi|447155290|ref|WP_001232546|]
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MULTISPECIES: putative lateral flagellar export/assembly protein LafU [Enterobacteriaceae]

Protein Classification

MotB family protein( domain architecture ID 11482413)

MotB family protein similar to Escherichia coli putative lateral flagellar export/assembly protein LafU that could be the product of a pseudogene

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06778 PRK06778
hypothetical protein; Validated
 12-300 0e+00

hypothetical protein; Validated


:

Pssm-ID: 235860 [Multi-domain]  Cd Length: 289  Bit Score: 581.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  12 AKTTIVRRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHP 91
Cdd:PRK06778   1 GATTIIKRANRKKHHVRHSGAWKVAFADFTLAMMALFMVLWIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  92 PKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGS 171
Cdd:PRK06778  81 PKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 172 AKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLL 251
Cdd:PRK06778 161 AQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 447155290 252 DSKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 300
Cdd:PRK06778 241 DAKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 289
 
Name Accession Description Interval E-value
PRK06778 PRK06778
hypothetical protein; Validated
 12-300 0e+00

hypothetical protein; Validated


Pssm-ID: 235860 [Multi-domain]  Cd Length: 289  Bit Score: 581.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  12 AKTTIVRRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHP 91
Cdd:PRK06778   1 GATTIIKRANRKKHHVRHSGAWKVAFADFTLAMMALFMVLWIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  92 PKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGS 171
Cdd:PRK06778  81 PKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 172 AKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLL 251
Cdd:PRK06778 161 AQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 447155290 252 DSKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 300
Cdd:PRK06778 241 DAKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 289
MotB COG1360
Flagellar motor protein MotB [Cell motility];
25-276 5.20e-47

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 155.77  E-value: 5.20e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  25 HAGHHGGAWKVAFADFTLAMMALFMTLWivnsvskseresiiaalhgqsifnggglsplnkispshppkpatvavpeete 104
Cdd:COG1360    2 EEGHHGGAWLVTYADLMTLLLAFFVLLW---------------------------------------------------- 29

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 105 kkardvnektallkkksatelgelatSINTIARDAHMEANLEMEIVPQGLRVLIKDdqnRNMFERGSAKIMPFFKTLLVE 184
Cdd:COG1360   30 --------------------------ALSSALEENLLSGQVEVRITEEGLVIEIQD---RVLFDSGSAELTPEGRELLDK 80

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 185 LAPVFDSLDNKIIITGHTDAMAYKNNIY-NNWNLSGDRALSARRVLEEAGMPEDKvMQVSAMADQMLLDSKN--PQSAGN 261
Cdd:COG1360   81 IAAVLAEVPNRIRVEGHTDNVPISTARFpSNWELSAARAAAVVRYLIEGGVPPER-LSAVGYGDTRPLAPNDtpEGRARN 159

                        250
                 ....*....|....*
gi 447155290 262 RRIEIMVLTKSASDT 276
Cdd:COG1360  160 RRVEIVILRRAAEEA 174
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 167-268 1.57e-18

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 79.13  E-value: 1.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 167 FERGSAKIMPFFKTLLVELAPVFDSLDN-KIIITGHTDAMAyknNIYNNWNLSGDRALSARRVLEEAGMPEDKvMQVSAM 245
Cdd:cd07185    6 FDFGSAELTPEAKPLLDKLAEVLKKNPDaKIRIEGHTDSRG---SDAYNQELSERRAEAVADYLVSKGVDASR-ITAVGY 81

                         90       100
                 ....*....|....*....|....*.
gi 447155290 246 ADQMLLDSkNPQSAG---NRRIEIMV 268
Cdd:cd07185   82 GESRPIAS-NDTEEGrakNRRVEIVI 106
type_VI_ompA TIGR03350
type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, ...
 145-268 6.61e-15

type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, the Gram-negative bacterial outer membrane protein OmpA (with an N-terminal outer membrane beta barrel domain) share a C-terminal peptidoglycan-associating homology region. This model describes a domain found fused to type VI secretion system homologs of the type IV system protein DotU (see model TIGR03349), with OmpA/MotB homology. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274533 [Multi-domain]  Cd Length: 137  Bit Score: 70.41  E-value: 6.61e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  145 LEMEIVPQGLRVLIKDD------QNRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIY-NNWNL 217
Cdd:TIGR03350   6 LAPEIAAGLLTVDEDGDrsvvrlRGDELFASGSAEVRAEFEPLLLRIAKALAAVPGRITVVGHTDNVPIRTARFpSNWHL 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 447155290  218 SGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDSKNPQS-AGNRRIEIMV 268
Cdd:TIGR03350  86 SEARAKAVADVLAQAGGPAGRVRAEGRGDSEPIASNATAAGrARNRRVEIDV 137
MotB_plug pfam13677
Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA ...
 18-69 8.69e-14

Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in Swiss:D3V2T1. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.


Pssm-ID: 463955 [Multi-domain]  Cd Length: 57  Bit Score: 64.85  E-value: 8.69e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 447155290   18 RRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAAL 69
Cdd:pfam13677   2 KKKKEPEHEGGHGERWLVTYADLMTLLLAFFVLLYSMSSVDEKKFQQIAESF 53
 
Name Accession Description Interval E-value
PRK06778 PRK06778
hypothetical protein; Validated
 12-300 0e+00

hypothetical protein; Validated


Pssm-ID: 235860 [Multi-domain]  Cd Length: 289  Bit Score: 581.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  12 AKTTIVRRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHP 91
Cdd:PRK06778   1 GATTIIKRANRKKHHVRHSGAWKVAFADFTLAMMALFMVLWIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  92 PKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGS 171
Cdd:PRK06778  81 PKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 172 AKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLL 251
Cdd:PRK06778 161 AQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 447155290 252 DSKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 300
Cdd:PRK06778 241 DAKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQ 289
motB PRK09041
motility protein MotB;
13-273 1.94e-73

motility protein MotB;


Pssm-ID: 236365 [Multi-domain]  Cd Length: 317  Bit Score: 228.67  E-value: 1.94e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  13 KTTIVRRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESI---------IAALHG------QSIFNG 77
Cdd:PRK09041   6 HPPIVVKRVKKKGHGHHGGSWKIAYADFMTAMMAFFLVMWLLSSSTPEQLIGIaeyfrtplkVALTGGdrssdsTSPIPG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  78 GGLSPLNKISPSHPPKPATVAVPEETEKKARdvnEKTALLKKksatelgELATSINTIARDAHMEANLEMEIVPQGLRVL 157
Cdd:PRK09041  86 GGDDITQQDGEVNKQPNIAELAQGEKERREQ---ERLEKLKQ-------ELDQAIESNPKLRQFKPQLLIDLTQEGLRIQ 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 158 IKDDQNRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKN--NIYNNWNLSGDRALSARRVLEEAGMP 235
Cdd:PRK09041 156 IVDSQNRPMFATGSAEVEPYMRDILREIAPVLNDVPNRISLSGHTDATPYANgeKGYSNWELSADRANASRRELVAGGMD 235

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 447155290 236 EDKVMQVSAMADQMLLDSKNPQSAGNRRIEIMVLTKSA 273
Cdd:PRK09041 236 EGKVLRVVGLASTMLLDKKDPLNPVNRRISIVVLNKKA 273
motB PRK12799
flagellar motor protein MotB; Reviewed
 16-273 6.93e-50

flagellar motor protein MotB; Reviewed


Pssm-ID: 183756 [Multi-domain]  Cd Length: 421  Bit Score: 170.67  E-value: 6.93e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  16 IVRRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVnSVSKSERESIIAALHGQSIfnGGGLSPLNKISPSHPPKPA 95
Cdd:PRK12799  10 LVKKRKTKHGAAHYGGSWKIAYADFMTAMMAFFLVMWLL-AVSSPQELTQIAEYFRTPL--KVALTSGDKSSSSTSPIPG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  96 TVAVPEETEKKA-RDVNEKTALLKKKSATELGE-LATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGSAK 173
Cdd:PRK12799  87 GGDDPTQQVGEVrKQINSEESRQEIHRLNKLREkLDQLIESDPRLKALRPHLLINMMDEGLRIQIIDSQNRPMFKMGSAQ 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 174 IMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNI--YNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLL 251
Cdd:PRK12799 167 VEPYMRDILRAIAPILNDIPNKLSLSGHTDDLPYARGErgYSNWELSADRANASRRELLAGGLDEGKILRVVGMASTMRL 246

                        250       260
                 ....*....|....*....|..
gi 447155290 252 DSKNPQSAGNRRIEIMVLTKSA 273
Cdd:PRK12799 247 KEQASDDPVNRRISILVLNKQS 268
MotB COG1360
Flagellar motor protein MotB [Cell motility];
25-276 5.20e-47

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 155.77  E-value: 5.20e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  25 HAGHHGGAWKVAFADFTLAMMALFMTLWivnsvskseresiiaalhgqsifnggglsplnkispshppkpatvavpeete 104
Cdd:COG1360    2 EEGHHGGAWLVTYADLMTLLLAFFVLLW---------------------------------------------------- 29

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 105 kkardvnektallkkksatelgelatSINTIARDAHMEANLEMEIVPQGLRVLIKDdqnRNMFERGSAKIMPFFKTLLVE 184
Cdd:COG1360   30 --------------------------ALSSALEENLLSGQVEVRITEEGLVIEIQD---RVLFDSGSAELTPEGRELLDK 80

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 185 LAPVFDSLDNKIIITGHTDAMAYKNNIY-NNWNLSGDRALSARRVLEEAGMPEDKvMQVSAMADQMLLDSKN--PQSAGN 261
Cdd:COG1360   81 IAAVLAEVPNRIRVEGHTDNVPISTARFpSNWELSAARAAAVVRYLIEGGVPPER-LSAVGYGDTRPLAPNDtpEGRARN 159

                        250
                 ....*....|....*
gi 447155290 262 RRIEIMVLTKSASDT 276
Cdd:COG1360  160 RRVEIVILRRAAEEA 174
motB PRK05996
MotB family protein;
16-268 3.55e-26

MotB family protein;


Pssm-ID: 235665 [Multi-domain]  Cd Length: 423  Bit Score: 107.09  E-value: 3.55e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  16 IVRRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESI------------------------------ 65
Cdd:PRK05996  15 IVRRGGDDDHEGHHGGVWKIAYADFMTAMMAFFLVMWLINAANEETKAAVasyfnpikltdrkpsekglkdpvdgaegeq 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  66 -------------------------------------------------IAALHGQ----SIFNGGGLS----------- 81
Cdd:PRK05996  95 kpgkskfeedqrvegssavtgddttrtsgdqtnyseadlfrnpyavlaeIAQEVGQqanvSAKGDGGAAqsgpatgadgg 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  82 ----------------PLNKISPSHPPKPATV-----------------AVPEETEKKARDVNEKTALLKKKSATELGEL 128
Cdd:PRK05996 175 eayrdpfdpdfwskqvEVTTAGDLLPPGQAREqaqgaksataapatvpqAAPLPQAQPKKAATEEELIADAKKAATGEPA 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 129 AT----SINTIARDAHMEANLE-------------------MEIVP--QGLRVLIKDDQNRNMFERGSAKIMPFFKTLLV 183
Cdd:PRK05996 255 ANaakaAKPEPMPDDQQKEAEQlqaaiaqaiggvagklaegVTVTPveGGLLISLTDQVDYGMFAIGSAVPRAELVLAME 334

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 184 ELAPVFDSLDNKIIITGHTDAMAYKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDSKNPQSAGNRR 263
Cdd:PRK05996 335 KIGQLLAERPGAVIIRGHTDARPFKSATYDNWRLSTARAQSAYYMLVRGGLDEKRIEQVEGFADRRPKLPNDPNAAANRR 414


                 ....*
gi 447155290 264 IEIMV 268
Cdd:PRK05996 415 IEILI 419
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 167-268 1.57e-18

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 79.13  E-value: 1.57e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 167 FERGSAKIMPFFKTLLVELAPVFDSLDN-KIIITGHTDAMAyknNIYNNWNLSGDRALSARRVLEEAGMPEDKvMQVSAM 245
Cdd:cd07185    6 FDFGSAELTPEAKPLLDKLAEVLKKNPDaKIRIEGHTDSRG---SDAYNQELSERRAEAVADYLVSKGVDASR-ITAVGY 81

                         90       100
                 ....*....|....*....|....*.
gi 447155290 246 ADQMLLDSkNPQSAG---NRRIEIMV 268
Cdd:cd07185   82 GESRPIAS-NDTEEGrakNRRVEIVI 106
motB PRK07734
flagellar motor protein MotB; Reviewed
 18-269 2.49e-17

flagellar motor protein MotB; Reviewed


Pssm-ID: 236080 [Multi-domain]  Cd Length: 259  Bit Score: 79.79  E-value: 2.49e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  18 RRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAALhgQSIFNGGG--LSPLNKISPSHPPKPA 95
Cdd:PRK07734   4 RKKKKKKHEEHIDESWLIPYADLLTLLLALFIVLFAMSSIDAAKFKQMAVAF--NSEFAGGTgvKDFLSDQKPEDEKELS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  96 TVAVPEETEKKardvNEKTALLKKKSATELGELATSINTIARDAHMEANLEMEIVPQGLRVLIKDDQnrnMFERGSAKIM 175
Cdd:PRK07734  82 ASSLEAEQAKK----KEEAEAKKKKEMEELKAVQKKIDQYIKEKQLSSSLQTKLTEEGLLITILDNI---LFDSGKADVR 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 176 PFFKTLLVELAP--VFDSLDNkIIITGHTDAMAYKNNIY-NNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLD 252
Cdd:PRK07734 155 LEDLPLAKEISNllVSNPPRN-ITISGHTDNVPIANAQFaSNWELSVMRAVNFMQVLLENKELDPEKFSAKGYGEYKPIA 233

                        250       260
                 ....*....|....*....|
gi 447155290 253 SkNPQSAG---NRRIEIMVL 269
Cdd:PRK07734 234 S-NDTAEGrakNRRVEVLIL 252
motB PRK08944
flagellar motor protein MotB; Reviewed
 32-269 2.68e-15

flagellar motor protein MotB; Reviewed


Pssm-ID: 236356 [Multi-domain]  Cd Length: 302  Bit Score: 74.66  E-value: 2.68e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  32 AWKVAFADFTLAMMALFMTLwivnsVSKSER---------ESIIAALHGQSIFNG----GGLSPL-NKISPSHP-PKP-- 94
Cdd:PRK08944  16 AWLATFADLMSLLMCFFVLL-----LSFSEMdvlkfkqiaGSMKFAFGVQNKIEVkdipKGTSIIaQEFRPGRPePTPie 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  95 ----ATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDA----------HMEANLEMEIVPQGLRVLIKD 160
Cdd:PRK08944  91 vimqQTIDMTQQTLEFQAGESDSAGGTQQQRGKQRGGEASAEVKAEKAAaqeqiedlvkKLAQQLEKEIEDGAIEIESLG 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 161 DQ------NRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIY-NNWNLSGDRALSARRVLEEAG 233
Cdd:PRK08944 171 QQiiirirEKGSFPSGSAFLQPKFKPVVRKIGELLKDVPGIITVSGHTDNVPISSELYrSNWDLSSARAVAVAHELLKVK 250

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 447155290 234 MPEDKVMQVSAMAD-QMLLDSKNPQS-AGNRRIEIMVL 269
Cdd:PRK08944 251 GFDPQRLKVVGMADtQPLVPNDTAENrARNRRVEIIIE 288
type_VI_ompA TIGR03350
type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, ...
 145-268 6.61e-15

type VI secretion system peptidoglycan-associated domain; The flagellar motor protein MotB, the Gram-negative bacterial outer membrane protein OmpA (with an N-terminal outer membrane beta barrel domain) share a C-terminal peptidoglycan-associating homology region. This model describes a domain found fused to type VI secretion system homologs of the type IV system protein DotU (see model TIGR03349), with OmpA/MotB homology. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274533 [Multi-domain]  Cd Length: 137  Bit Score: 70.41  E-value: 6.61e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  145 LEMEIVPQGLRVLIKDD------QNRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIY-NNWNL 217
Cdd:TIGR03350   6 LAPEIAAGLLTVDEDGDrsvvrlRGDELFASGSAEVRAEFEPLLLRIAKALAAVPGRITVVGHTDNVPIRTARFpSNWHL 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 447155290  218 SGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDSKNPQS-AGNRRIEIMV 268
Cdd:TIGR03350  86 SEARAKAVADVLAQAGGPAGRVRAEGRGDSEPIASNATAAGrARNRRVEIDV 137
MotB_plug pfam13677
Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA ...
 18-69 8.69e-14

Membrane MotB of proton-channel complex MotA/MotB; This is the MotB member of the E.coli MotA/MotB proton-channel complex that forms the stator of the bacterial membrane flagellar motor. Key residues act as a plug to prevent premature proton flow. The plug is in the periplasm just C-terminal to the MotB TM, consisting of an amphipathic alpha helix flanked by Pro-52 and Pro-65, eg in Swiss:D3V2T1. In addition to the Pro residues, Ile-58, Tyr-61, and Phe 62 are also essential for plug function.


Pssm-ID: 463955 [Multi-domain]  Cd Length: 57  Bit Score: 64.85  E-value: 8.69e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 447155290   18 RRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAAL 69
Cdd:pfam13677   2 KKKKEPEHEGGHGERWLVTYADLMTLLLAFFVLLYSMSSVDEKKFQQIAESF 53
OmpA pfam00691
OmpA family; The Pfam entry also includes MotB and related proteins which are not included in ...
 167-263 1.34e-13

OmpA family; The Pfam entry also includes MotB and related proteins which are not included in the Prosite family.


Pssm-ID: 425825 [Multi-domain]  Cd Length: 95  Bit Score: 65.46  E-value: 1.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  167 FERGSAKIMPFFKTLLVELAPV--FDSLDNKIIITGHTDAMAYKNNiynNWNLSGDRALSARRVLEEAGMPEDKVMqVSA 244
Cdd:pfam00691   1 FDPGSSQLTPKAKATLDEIADLlkFPELKNTITIEGHTDTVGSAAY---NWELSQRRAEAVRRYLVNFGVPPSRIS-VVG 76

                          90
                  ....*....|....*....
gi 447155290  245 MADQMLLDSKNPQSAGNRR 263
Cdd:pfam00691  77 YGATKPITDNKTPEGRARN 95
PRK06925 PRK06925
flagellar motor protein MotB;
18-269 2.79e-12

flagellar motor protein MotB;


Pssm-ID: 235887 [Multi-domain]  Cd Length: 230  Bit Score: 65.17  E-value: 2.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  18 RRQIKknhagHHGGA--WKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAALHGQSIFNGGglsplnkisPSHPPKPA 95
Cdd:PRK06925   3 RRKRQ-----QSKGSpkWMVTFSDLITLILVFFILLFSMSQIDAQKFKAAVESFQQRGSLGFL---------PSAIEFEN 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  96 TVAVPEETEKKARDVNEktaLLKKksatelgelatsINTIARDAHMEANLEMEIVPQGLrVLIKddQNRNMFERGSAKIM 175
Cdd:PRK06925  69 PAESSEDEEKQEDQLDE---LLKK------------VNEYIEENELKSVITAKRDERGV-VLVL--QEAVLFETGEADIL 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 176 PFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIY-NNWNLSGDRALSA-RRVLEEAGMPEDKVMQVSAMADQMLLDS 253
Cdd:PRK06925 131 KQAEPFLHKIGVLLSTIPNDIKVEGHTDSRPISTYRYpSNWELSAARASSViRYFTSKEKLDSSRFIAVGYADTKPVVPN 210

                        250
                 ....*....|....*..
gi 447155290 254 KNPQS-AGNRRIEIMVL 269
Cdd:PRK06925 211 TTEENmQENRRVEIVIS 227
PRK09038 PRK09038
flagellar motor protein MotD; Reviewed
 18-269 8.28e-11

flagellar motor protein MotD; Reviewed


Pssm-ID: 181618 [Multi-domain]  Cd Length: 281  Bit Score: 61.57  E-value: 8.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  18 RRQIKKNHAGHHggAWKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAALHGqsIFNGGGLS----PLNKISP-SHPP 92
Cdd:PRK09038   4 RRKHHEEHENHE--RWLVSYADFITLLFAFFVVMYAISSVNEGKYKVLSEALTG--AFNGPSRSmkpiPIGKEQPkTTQP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  93 KPATVAVPEETEKKARDvnektallkkksatelgelatSINTIARDAHMEanlemeivpqgLRVLIKDDQ---NRN---- 165
Cdd:PRK09038  80 ARPLVIDSEQPDARAQD---------------------QLKTIADDLRKA-----------LGPLIESGQvtvRRNelwi 127

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 166 --------MFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIY-NNWNLSGDRALSARRVLEEAGMPE 236
Cdd:PRK09038 128 eieinsslLFGSGDAMLSDQAFAILEKVAEVLKPAPNPIHVEGFTDNVPIATAQFpSNWELSAARAASVVRLLADDGVAP 207

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 447155290 237 DKVMQVSAMADQMLLDskNPQSAG---NRRIEIMVL 269
Cdd:PRK09038 208 SRLAAVGYGEFQPVAD--NDTAEGrarNRRVVLVIL 241
OmpA COG2885
Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall ...
 167-271 9.75e-11

Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442131 [Multi-domain]  Cd Length: 294  Bit Score: 61.34  E-value: 9.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 167 FERGSAKIMPFFKTLLVELAPVFDSLDN-KIIITGHTDAM---AYknniynNWNLSGDRALSARRVLEEAGMPEDKvMQV 242
Cdd:COG2885  191 FDFDSAELTPEAKAALDELAALLKENPDlRIEIEGHTDSRgsdAY------NLALSERRAEAVKDYLVSKGIPASR-ITA 263

                         90       100       110
                 ....*....|....*....|....*....|..
gi 447155290 243 SAMADQMLLDSkNPQSAG---NRRIEIMVLTK 271
Cdd:COG2885  264 VGYGESRPVAS-NDTEEGrakNRRVEIVVLKK 294
motB PRK08457
flagellar motor protein MotB; Reviewed
 30-274 4.72e-10

flagellar motor protein MotB; Reviewed


Pssm-ID: 181435 [Multi-domain]  Cd Length: 257  Bit Score: 58.96  E-value: 4.72e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  30 GGAWKVAFADFTLAMMALFMTLWIVNSVSKSEREsiiaALHGQ--SIFNggglsplnkispsHPPKPATVAVPEETEKKA 107
Cdd:PRK08457  13 GEKWAVPYADFLSLLLALFIALYAISAVNKAKVE----ALKTEfiKIFD-------------YTAKPEVKQPVKVIPPDS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 108 RDVNEKTALLKKKSATELgelaTSINTIARDAHMEANLEMEI------VPQGLrvlikddqnrnMFERGSAKI-----MP 176
Cdd:PRK08457  76 GDAEEEMDELKSLKASQN----TQQETIERRKGEGGALDQIDngialkLPSKL-----------LFENGSAEIinadmMD 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 177 FFKTllveLAPVFDSL--DNKIIITGHTDAMAYKNNIY-NNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDS 253
Cdd:PRK08457 141 YLKR----IAKIITKLpkQVKINVRGYTDNSPLNKSRYkDHYELAAARAYNVMKVLIQYGINPNRLSFSSYGSNNPIAPN 216

                        250       260
                 ....*....|....*....|..
gi 447155290 254 KNPQS-AGNRRIEIMVLTKSAS 274
Cdd:PRK08457 217 DSLENrLKNNRVEIFFKVDAND 238
motB PRK06667
flagellar motor protein MotB; Validated
 16-270 7.24e-10

flagellar motor protein MotB; Validated


Pssm-ID: 180652 [Multi-domain]  Cd Length: 252  Bit Score: 58.27  E-value: 7.24e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  16 IVRRQIKKNHAGHHGGAWKVAFADFTLAMMALFMTLWIVNSVSKSERESIIAALHGQSIFNGG---GLSPLNKISPSHPP 92
Cdd:PRK06667   1 MAMRKKKCPKCIQGAPEYMLTYGDMVTLLLCFFVMLFTTNDVDENVLQIISASFTGTGFFKGGqtlSKGKLSELGNSIMS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290  93 KPATvavpeETEKKARDVnektallkKKSATELGELATSINTIARDAHmeanlemeivPQGLRV-LIKDDqnrnMFERGS 171
Cdd:PRK06667  81 LPST-----EKGKQLSQA--------KKNASSLFKPEIQSNKVAVTED----------ERGLVIsLASDA----FFYPGS 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 172 AKI-MPFFKTLLVELAPVFDSLDN---KIIITGHTDAMAYK-NNIY-NNWNLSGDRALSARRVLEEAGMPEDKVMQVSAM 245
Cdd:PRK06667 134 AEVkLEENRETLQKIASFIGFLDLagrNFRIEGHTDNVDVNpEGPWkSNWELSGARAVNMLEYILNYGDQSESWFQVSGF 213

                        250       260
                 ....*....|....*....|....*..
gi 447155290 246 ADQ--MLLDSKNPQSAGNRRIEIMVLT 270
Cdd:PRK06667 214 AGSrpLATEDTPEGRAYNRRIDIVILT 240
PRK06742 PRK06742
flagellar motor protein MotS; Reviewed
 153-268 2.06e-08

flagellar motor protein MotS; Reviewed


Pssm-ID: 102525 [Multi-domain]  Cd Length: 225  Bit Score: 53.91  E-value: 2.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 153 GLRVLIKDDQnrnMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKN-NIYNNWNLSGDRALSARRVLEE 231
Cdd:PRK06742 108 GVSVVIVDNL---IFDTGDANVKPEAKEIISQLVGFFQSVPNPIVVEGHTDSRPIHNdKFPSNWELSSARAANMIHHLIE 184

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 447155290 232 AGMPEDKVMQVSAMAD-QMLLDSKNPQS-AGNRRIEIMV 268
Cdd:PRK06742 185 VYNVDDKRLAAVGYADtKPVVPNDSPQNwEKNRRVVIYI 223
PRK08126 PRK08126
hypothetical protein; Provisional
 166-268 8.35e-06

hypothetical protein; Provisional


Pssm-ID: 236157 [Multi-domain]  Cd Length: 432  Bit Score: 47.00  E-value: 8.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 166 MFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIY-NNWNLSGDRALSARRVLEEAGMPEDKVMQVSA 244
Cdd:PRK08126 326 MFVPGQATVNPAMGPLIAKIAREIARVGGKVTVTGHTDNQPIRSAQFaSNLVLSEKRAAQVAQMLQSAGVPASRLEAVGK 405

                         90       100
                 ....*....|....*....|....*
gi 447155290 245 MADQMLLDSKNPQS-AGNRRIEIMV 268
Cdd:PRK08126 406 GDAQPVADNRTPQGrAQNRRVEITV 430
PRK09040 PRK09040
hypothetical protein; Provisional
 166-276 8.61e-06

hypothetical protein; Provisional


Pssm-ID: 181620 [Multi-domain]  Cd Length: 214  Bit Score: 45.78  E-value: 8.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 166 MFERGSAKIMPFFKTLLVELAP----VFDSLDNKIIITGHTDAMAYK--NNIY-NNWNLSGDRALSARRVLEEAGMPEDK 238
Cdd:PRK09040  91 LFALNSDQLQPEGRELLKSLAGplaaYLRARDEILMVSGFTDDQPVRagNRRFaDNWELSAQRALTVTRALIDAGVPASS 170

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 447155290 239 VMQVSAMADQMLldSKNPQSAG---NRRIEIMVLTKSASDT 276
Cdd:PRK09040 171 VFAAAFGSEQPV--ASNADDEGrakNRRVEIAPVPRPSASA 209
PRK07033 PRK07033
DotU family type VI secretion system protein;
145-269 4.08e-05

DotU family type VI secretion system protein;


Pssm-ID: 180801 [Multi-domain]  Cd Length: 427  Bit Score: 44.66  E-value: 4.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 145 LEMEIvPQGLrVLIKDDQNRN--------MFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNIY-NNW 215
Cdd:PRK07033 290 LEPEI-RAGL-VAVRDEADRSvvtlrgdgLFASASTSVRDRYQPVLARVADALNQVKGNVLVTGYSDNVPIRTARFpSNW 367

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 447155290 216 NLSGDRALSARRVLE-EAGMPEDKVMQVSAMADQMLLDSKNPQSAGNRRIEIMVL 269
Cdd:PRK07033 368 ELSQARAQAVRALLAaRLGQPERVTAEGRGDSDPVAPNDSAENRARNRRVEITLL 422
PRK09039 PRK09039
peptidoglycan -binding protein;
166-266 8.21e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.80  E-value: 8.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447155290 166 MFERGSAKIMPFFKTLLVELAPVFDSLDNKI------II--TGHTD------AMAYKNNiynnWNLSGDRALSARRVLEE 231
Cdd:PRK09039 227 LFPTGSAELNPEGQAEIAKLAAALIELAKEIppeinwVLrvDGHTDnvplsgTGRFRDN----WELSSARAISVVKFLIA 302

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 447155290 232 AGMPEDKVMqVSAMADQMLLDSKNPQSA--GNRRIEI 266
Cdd:PRK09039 303 LGVPADRLA-AAGFGEFQPLDPGDTPEAraRNRRIEL 338
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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