|
Name |
Accession |
Description |
Interval |
E-value |
| pstA |
PRK11268 |
phosphate ABC transporter permease PstA; |
1-295 |
0e+00 |
|
phosphate ABC transporter permease PstA;
Pssm-ID: 183065 [Multi-domain] Cd Length: 295 Bit Score: 578.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 1 MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLA 80
Cdd:PRK11268 1 MATVEMQNTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITLGIDGMSLALFTEMTPPPNTAGGGLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 81 NALAGSGLLILWATVFGTPLGIMAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL 160
Cdd:PRK11268 81 NAIAGSGLLILWATVVGTPLGIMAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 161 ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWST 240
Cdd:PRK11268 161 ALLQIPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGVLLAIARIAGETAPLLFTALSNQFWST 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 447174735 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIITLCVLLLNILARVVFAKNKH 295
Cdd:PRK11268 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLCVLLLNILARVVFAKKKH 295
|
|
| PstA |
COG0581 |
ABC-type phosphate transport system, permease component [Inorganic ion transport and ... |
40-292 |
1.25e-114 |
|
ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440346 [Multi-domain] Cd Length: 259 Bit Score: 330.85 E-value: 1.25e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 40 FGLFWLIWILMSTITRGIDGMSLALFTEMtPPPNTEGGGLANALAGSGLLILWATVFGTPLGIMAGIYLAEYGRKSWLAE 119
Cdd:COG0581 1 LALLPLVWILGTVLVKGLPALSWEFLTSS-PSPGPEGGGILPAIVGTLLLVLLATLIAVPLGVLAAIYLAEYARGGRLAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 120 VIRFINDILLSAPSIVVGLFVYTIVVAQM-EHFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMI 198
Cdd:COG0581 80 LIRFAIDVLAGVPSIVYGLFGYALFVLTLgLGFSLLAGALALALLMLPVVIRTTEEALRLVPNSLREASYALGATKWQTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 199 SAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIITLC 278
Cdd:COG0581 160 RKVVLPAALPGILTGVILAIARAAGETAPLLFTAGVSPFLPLSLFDPFATLPVHIYNLASSPYPAAQELAWAAALVLLLL 239
|
250
....*....|....
gi 447174735 279 VLLLNILARVVFAK 292
Cdd:COG0581 240 VLLLNLLARLLRRR 253
|
|
| 3a0107s02c |
TIGR00974 |
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ... |
27-294 |
4.07e-86 |
|
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]
Pssm-ID: 273373 Cd Length: 271 Bit Score: 258.70 E-value: 4.07e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 27 NRIALTLSMATMAFGLFWLIWILMSTITRGIDGMSLALFTEMTPPPNTEGGgLANALAGSGLLILWATVFGTPLGIMAGI 106
Cdd:TIGR00974 1 DKIFTFISLLSALLALLPLIWILWYILIKGLPALNLEFFTKSPTPTGAEGG-IGPAIVGTLLLTLLAIVIAVPLGIGAAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 107 YLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQME--HFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLR 184
Cdd:TIGR00974 80 YLAEYANGSRFTKIIRFAVDILAGVPSIVVGLFGYGFFVLTYLggGFSLLAGALALALLILPVIIRTTEEALKAVPKDLR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 185 EAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFA-MSPFAE 263
Cdd:TIGR00974 160 EASLALGATKWQTIFKVVLPAALPGILTGIILSIARAAGETAPLLFTAGGSAFTPPNLFDPFATLPVLIYNLAsEGPYVE 239
|
250 260 270
....*....|....*....|....*....|.
gi 447174735 264 WQQLAWAGVLIITLCVLLLNILARVVFAKNK 294
Cdd:TIGR00974 240 AQQLAWAAALVLIVLVLLLNLIARLLRRRFK 270
|
|
| TM_PBP2 |
cd06261 |
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ... |
83-238 |
6.16e-17 |
|
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.
Pssm-ID: 119394 [Multi-domain] Cd Length: 190 Bit Score: 76.93 E-value: 6.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 83 LAGSGLLILWATVFGTPLGIMAGIYLAEYGRksWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQM----EHFSGWAGVI 158
Cdd:cd06261 1 LLNTLLLALIATLLALVLGLLLGIILARKRG--KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgiLPGLGLPALI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 159 ALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFW 238
Cdd:cd06261 79 LALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG 158
|
|
| BPD_transp_1 |
pfam00528 |
Binding-protein-dependent transport system inner membrane component; The alignments cover the ... |
101-289 |
2.77e-16 |
|
Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.
Pssm-ID: 334128 [Multi-domain] Cd Length: 183 Bit Score: 75.03 E-value: 2.77e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 101 GIMAGIYLAEYgRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIALALLQVPIVIRTTENMLKLVP 180
Cdd:pfam00528 1 GIPLGIIAALR-RGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 181 DSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFwSTDMMQPIANlpvtifkfamSP 260
Cdd:pfam00528 80 SDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL-GLLLIEAILG----------YD 148
|
170 180
....*....|....*....|....*....
gi 447174735 261 FAEWQQLAWAGVLIITLCVLLLNILARVV 289
Cdd:pfam00528 149 YPEIQGPVLAAALILLLLNLLVDILQRLL 177
|
|
| ABC_perm1 |
NF038017 |
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ... |
83-224 |
3.18e-07 |
|
ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.
Pssm-ID: 411610 [Multi-domain] Cd Length: 184 Bit Score: 49.47 E-value: 3.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 83 LAGSGLLILWATVFGTPLGimAGIYLAEYGRKSWlaeVIRFINdILLSAPSIVVGLFVYTIV-----VAQMEH-FSGWAG 156
Cdd:NF038017 2 LRVSGTATLIAALIGIPLG--ALLALRRFPGRRL---VISLLN-TLMGLPPVVVGLIVYLLLsrsgpLGFLGLlYTPTAM 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447174735 157 VIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAItLKASVSGIMTGILLAIARIAGE 224
Cdd:NF038017 76 IIAQAVLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTL-LKEARFALLAAVLAGFGRAISE 142
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pstA |
PRK11268 |
phosphate ABC transporter permease PstA; |
1-295 |
0e+00 |
|
phosphate ABC transporter permease PstA;
Pssm-ID: 183065 [Multi-domain] Cd Length: 295 Bit Score: 578.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 1 MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLA 80
Cdd:PRK11268 1 MATVEMQNTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITLGIDGMSLALFTEMTPPPNTAGGGLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 81 NALAGSGLLILWATVFGTPLGIMAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL 160
Cdd:PRK11268 81 NAIAGSGLLILWATVVGTPLGIMAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 161 ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWST 240
Cdd:PRK11268 161 ALLQIPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGVLLAIARIAGETAPLLFTALSNQFWST 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 447174735 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIITLCVLLLNILARVVFAKNKH 295
Cdd:PRK11268 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLCVLLLNILARVVFAKKKH 295
|
|
| PstA |
COG0581 |
ABC-type phosphate transport system, permease component [Inorganic ion transport and ... |
40-292 |
1.25e-114 |
|
ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440346 [Multi-domain] Cd Length: 259 Bit Score: 330.85 E-value: 1.25e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 40 FGLFWLIWILMSTITRGIDGMSLALFTEMtPPPNTEGGGLANALAGSGLLILWATVFGTPLGIMAGIYLAEYGRKSWLAE 119
Cdd:COG0581 1 LALLPLVWILGTVLVKGLPALSWEFLTSS-PSPGPEGGGILPAIVGTLLLVLLATLIAVPLGVLAAIYLAEYARGGRLAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 120 VIRFINDILLSAPSIVVGLFVYTIVVAQM-EHFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMI 198
Cdd:COG0581 80 LIRFAIDVLAGVPSIVYGLFGYALFVLTLgLGFSLLAGALALALLMLPVVIRTTEEALRLVPNSLREASYALGATKWQTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 199 SAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIITLC 278
Cdd:COG0581 160 RKVVLPAALPGILTGVILAIARAAGETAPLLFTAGVSPFLPLSLFDPFATLPVHIYNLASSPYPAAQELAWAAALVLLLL 239
|
250
....*....|....
gi 447174735 279 VLLLNILARVVFAK 292
Cdd:COG0581 240 VLLLNLLARLLRRR 253
|
|
| 3a0107s02c |
TIGR00974 |
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ... |
27-294 |
4.07e-86 |
|
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]
Pssm-ID: 273373 Cd Length: 271 Bit Score: 258.70 E-value: 4.07e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 27 NRIALTLSMATMAFGLFWLIWILMSTITRGIDGMSLALFTEMTPPPNTEGGgLANALAGSGLLILWATVFGTPLGIMAGI 106
Cdd:TIGR00974 1 DKIFTFISLLSALLALLPLIWILWYILIKGLPALNLEFFTKSPTPTGAEGG-IGPAIVGTLLLTLLAIVIAVPLGIGAAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 107 YLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQME--HFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLR 184
Cdd:TIGR00974 80 YLAEYANGSRFTKIIRFAVDILAGVPSIVVGLFGYGFFVLTYLggGFSLLAGALALALLILPVIIRTTEEALKAVPKDLR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 185 EAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFA-MSPFAE 263
Cdd:TIGR00974 160 EASLALGATKWQTIFKVVLPAALPGILTGIILSIARAAGETAPLLFTAGGSAFTPPNLFDPFATLPVLIYNLAsEGPYVE 239
|
250 260 270
....*....|....*....|....*....|.
gi 447174735 264 WQQLAWAGVLIITLCVLLLNILARVVFAKNK 294
Cdd:TIGR00974 240 AQQLAWAAALVLIVLVLLLNLIARLLRRRFK 270
|
|
| PstC |
COG0573 |
ABC-type phosphate transport system, permease component [Inorganic ion transport and ... |
13-294 |
6.87e-35 |
|
ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440338 [Multi-domain] Cd Length: 303 Bit Score: 127.90 E-value: 6.87e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 13 AESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITRGIDGMS----LALFTEMTPPPNTEGG--GLANALAGS 86
Cdd:COG0573 3 SSRLRPRRRRRRLGDRLFRGLLLLAALLSILILLLIVLFLLIESLPAFQevglLEFLTGTEWNPVSSNGefGILPLIVGT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 87 GLLILWATVFGTPLGIMAGIYLAEYGRKsWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGW--------AGVI 158
Cdd:COG0573 83 LLVSLIALLIAVPLGLGIAIFLSEYAPP-RLRRILKPAIELLAGIPSVVYGFWGLFVLVPLLRDLFPWppsgfsllTAGI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 159 ALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGET-APLLFTALSNQF 237
Cdd:COG0573 162 VLAIMILPTITSLSRDALRAVPRSLREAALALGATRWETIRKVVLPAARSGIIAAVILGLGRALGETmAVLMVAGNAPQI 241
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 447174735 238 wSTDMMQPIANLPVTI-FKFAMSPFAEWQQLA-WAGVLIITLCVLLLNILARVVFAKNK 294
Cdd:COG0573 242 -PFSLFDPGRTLTALIaLEFGEAPFGSLHYSAlFALGLVLFVITLLVNLLARLIVRRYR 299
|
|
| phosphate_pstC |
TIGR02138 |
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ... |
72-294 |
8.20e-24 |
|
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]
Pssm-ID: 273992 [Multi-domain] Cd Length: 295 Bit Score: 98.11 E-value: 8.20e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 72 PNTEGGGLANALAGSGLLILWATVFGTPLGIMAGIYLAEYGRKsWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQME-H 150
Cdd:TIGR02138 54 PVQEQYGALPLIVGTLITSLIALLIAVPVGIGIAIFLSEIAPK-RVRSVLKPVVELLAGIPSVVYGFWGLFVLVPFLKpH 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 151 FSGW----------------AGVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGI 214
Cdd:TIGR02138 133 FQPFlgsnlgliplfggpilTAGIVLAIMILPTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAV 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 215 LLAIARIAGET-APLLFTALSNQFWSTDMMQPIANLPVTI-FKFAMSPFAEWQQLA-WAGVLIITLCVLLLNILARVVFA 291
Cdd:TIGR02138 213 VLGLGRALGETmAVTMVIGNVFPISPLSLFDPGTTITSLIaNQFGEASGGSVHTSAlFALGLVLFVITLLVNILARYIVR 292
|
...
gi 447174735 292 KNK 294
Cdd:TIGR02138 293 RRR 295
|
|
| TM_PBP2 |
cd06261 |
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ... |
83-238 |
6.16e-17 |
|
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.
Pssm-ID: 119394 [Multi-domain] Cd Length: 190 Bit Score: 76.93 E-value: 6.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 83 LAGSGLLILWATVFGTPLGIMAGIYLAEYGRksWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQM----EHFSGWAGVI 158
Cdd:cd06261 1 LLNTLLLALIATLLALVLGLLLGIILARKRG--KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLgwgiLPGLGLPALI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 159 ALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFW 238
Cdd:cd06261 79 LALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG 158
|
|
| BPD_transp_1 |
pfam00528 |
Binding-protein-dependent transport system inner membrane component; The alignments cover the ... |
101-289 |
2.77e-16 |
|
Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.
Pssm-ID: 334128 [Multi-domain] Cd Length: 183 Bit Score: 75.03 E-value: 2.77e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 101 GIMAGIYLAEYgRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIALALLQVPIVIRTTENMLKLVP 180
Cdd:pfam00528 1 GIPLGIIAALR-RGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 181 DSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFwSTDMMQPIANlpvtifkfamSP 260
Cdd:pfam00528 80 SDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL-GLLLIEAILG----------YD 148
|
170 180
....*....|....*....|....*....
gi 447174735 261 FAEWQQLAWAGVLIITLCVLLLNILARVV 289
Cdd:pfam00528 149 YPEIQGPVLAAALILLLLNLLVDILQRLL 177
|
|
| FbpB |
COG1178 |
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; |
15-288 |
3.69e-11 |
|
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440791 [Multi-domain] Cd Length: 538 Bit Score: 63.26 E-value: 3.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 15 SRRKMQARRRLKNRIALTLSMATMAFGLFW-LIWILMSTITRGID-GMSLALFTEMTPPPnteggGLANALAGSGLLILW 92
Cdd:COG1178 275 ARRPRRVKLGRWRWLALALCLLLVLLGLLLpLLALLLWSLTKALDdNLTLDNYRFVLLDP-----SLLRALLNSLLLALL 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 93 ATVFGTPLGIMAGIYLAEygRKSWLAEVIRFINDILLSAPSIVVG---LFVYTIVVAQMEHFSGWAGVIALALLQVPIVI 169
Cdd:COG1178 350 AALLAVLLALLLAYLVRR--RRGRLARLLDRLAMLPYAVPGIVLGlglLLLFNRPLPLLLYGTLAILVLAYVVRFLPFAL 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 170 RTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFtaLSNQFWSTdmmqpianL 249
Cdd:COG1178 428 RSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLL--LRPPGFET--------L 497
|
250 260 270
....*....|....*....|....*....|....*....
gi 447174735 250 PVTIFKFAMSPFaeWQQLAWAGVLIITLCVLLLNILARV 288
Cdd:COG1178 498 AVLIYQLASSGR--YGEAAALALLLVLVSLLPVLLLERL 534
|
|
| PotC |
COG1177 |
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ... |
78-294 |
4.09e-08 |
|
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];
Pssm-ID: 440790 [Multi-domain] Cd Length: 262 Bit Score: 53.19 E-value: 4.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 78 GLANALAGSGLLILWATVFGTPLGIMAGIYLAEYgrKSWLAEVIRFINDILLSAPSIVVGLFVYtIVVAQMEHFSGWAGV 157
Cdd:COG1177 58 RLLDALLNSLLIALLSTLLATVLGTPAALALARY--RFRGRRLLLALLLLPLVVPGIVLGVALL-LLFSALGLSGGLWGL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 158 I-ALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQ 236
Cdd:COG1177 135 IlAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGV 214
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447174735 237 fwstdmmqpiANLPVTIF---KFAMSPFAewqqlAWAGVLIITLCVLLLNILARVVFAKNK 294
Cdd:COG1177 215 ----------TTLPVYIYsmiRRGISPEI-----NALSTLLILLSLLLLLLAERLRRRGER 260
|
|
| ABC_perm1 |
NF038017 |
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ... |
83-224 |
3.18e-07 |
|
ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.
Pssm-ID: 411610 [Multi-domain] Cd Length: 184 Bit Score: 49.47 E-value: 3.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 83 LAGSGLLILWATVFGTPLGimAGIYLAEYGRKSWlaeVIRFINdILLSAPSIVVGLFVYTIV-----VAQMEH-FSGWAG 156
Cdd:NF038017 2 LRVSGTATLIAALIGIPLG--ALLALRRFPGRRL---VISLLN-TLMGLPPVVVGLIVYLLLsrsgpLGFLGLlYTPTAM 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447174735 157 VIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAItLKASVSGIMTGILLAIARIAGE 224
Cdd:NF038017 76 IIAQAVLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTL-LKEARFALLAAVLAGFGRAISE 142
|
|
| OpuBB |
COG1174 |
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ... |
60-214 |
8.08e-06 |
|
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440787 [Multi-domain] Cd Length: 212 Bit Score: 45.82 E-value: 8.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 60 MSLALFTEMTpppnTEGGGLANALAGSGLLILWATVFGTPLGIMAGIYLaeyGRKSWLAEVIRFINDILLSAPSIvvGLF 139
Cdd:COG1174 1 MNLSLIEWLA----DNRDGILALLLEHLLLVLLALLIALLIAVPLGILI---TRRRRLAGLVLGVANILQTIPSL--ALL 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447174735 140 VYTIVVAQmehFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGI 214
Cdd:COG1174 72 ALLIPLLG---IGPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGI 143
|
|
| CysU |
COG0555 |
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ... |
91-232 |
1.84e-05 |
|
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440321 [Multi-domain] Cd Length: 268 Bit Score: 45.13 E-value: 1.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 91 LWATVFGTPLGIMAGIYLAEY---GRKswlaeVIRFINDILLSAPSIVVG-----LFVYTIVVAQMEH-------FSGWA 155
Cdd:COG0555 64 LIAALINLVFGLPLAWVLVRYrfpGKR-----LVDALVDLPFALPTAVAGialllLFGPNGWLGQLLAplgikvaFTPLG 138
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 447174735 156 GVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTA 232
Cdd:COG0555 139 IVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEFGAVIFIA 215
|
|
| cysT |
CHL00187 |
sulfate transport protein; Provisional |
26-224 |
2.19e-05 |
|
sulfate transport protein; Provisional
Pssm-ID: 214388 [Multi-domain] Cd Length: 237 Bit Score: 44.62 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 26 KNRIALTLSMA---TMAFGLFWLIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLANALAgsglliLWATVFGTPLGI 102
Cdd:CHL00187 3 DFNFSLKFSSIyiiSLSYIIFLLVLPILALLIKASQQPWSDFLQKATEPIALSAYSLTLSMA------LIAALINGFFGL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 103 MAGIYLAEY---GRKSWLAEVirfinDILLSAPSIVVGLFVYTIVVAQ--MEHFSGWAGV--------IALALLQV--PI 167
Cdd:CHL00187 77 LIAWVLVRYnfpGKRLLDAAV-----DLPFALPTSVAGLTLATVYGDNgwIGHLLSHLGIqivftklgVLLAMIFVsfPF 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 447174735 168 VIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGE 224
Cdd:CHL00187 152 VVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGE 208
|
|
| DppB |
COG0601 |
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ... |
79-291 |
2.32e-04 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440366 [Multi-domain] Cd Length: 314 Bit Score: 41.98 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 79 LANALAGSGLLILWATVFGTPLGIMAGIYLAeYGRKSWLAEVIRFINDILLSAPSIVVGL-----FVYTI-------VVA 146
Cdd:COG0601 91 IAERLPVTLELALLALLLALLIGIPLGILAA-LRRGSWLDRLITVLALLGISIPSFWLGLllillFAVKLgwlpvsgRVS 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 147 QMEHFSGWAG-----VIALALLQVPIVIRTT-ENMLklvpDSLRE----AAYALGTPKWKMISAITLKASVSGIMTGILL 216
Cdd:COG0601 170 PWEDFLDALRhlilpALTLALGSLAGIARLTrSSML----EVLGQdyvrTARAKGLSERRVLLRHALRNALIPVVTVLGL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 217 AIARIAG-----ET-------APLLFTALSNQfwstdmmqpiaNLPVTIfkfamspfaewqqlawAGVLIITLCVLLLNI 284
Cdd:COG0601 246 QLGGLLGgavvvETvfswpglGRLLVDAILNR-----------DYPVVQ----------------GIVLLIAVLVVLVNL 298
|
....*..
gi 447174735 285 LARVVFA 291
Cdd:COG0601 299 LVDLLYA 305
|
|
| modB |
PRK09421 |
molybdate ABC transporter permease subunit; |
91-224 |
3.15e-04 |
|
molybdate ABC transporter permease subunit;
Pssm-ID: 181841 Cd Length: 229 Bit Score: 41.06 E-value: 3.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 91 LWATVFGTPLGIMAGIYLA--EYGRKSWLAEVIRfindILLSAPSIVVG-----LFVYTIVVAQM--EHFS-----GWAG 156
Cdd:PRK09421 19 SVAVLFSLPFGILVAWLLArcRFPGKSLLDSLLH----LPLVLPPVVTGyllliSMGRRGFIGQWlyEWFGisfafSWRG 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 447174735 157 -VIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGE 224
Cdd:PRK09421 95 aALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGE 163
|
|
| FbpB |
COG1178 |
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; |
19-217 |
4.42e-04 |
|
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440791 [Multi-domain] Cd Length: 538 Bit Score: 41.69 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 19 MQARRRLKNRIALTLSMATMAFGLFW-LIWILMSTITRGIDGMSLALFTEMTPppnteggglaNALAGSGLLILWATVFG 97
Cdd:COG1178 1 MSTRPRRRPRLLLLLLALLLALLVLLpLLALLLRAFTDGLANFWALLSDPYLW----------RALGNTLLLALLVTLLS 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 98 TPLGIMAGIYLAEY---GRKswlaeVIRFINDILLSAPSIVVG-----LFVYTIVVAQMEH----------FSGWAGVIA 159
Cdd:COG1178 71 LLLGVPLAWLLARTdfpGRR-----LLRWLLLLPLALPPYVVAlawiaLFGPNGLLNTLLRalfgleppdiYGLGGIILV 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 447174735 160 LALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLA 217
Cdd:COG1178 146 LVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLV 203
|
|
| pstC |
PRK11275 |
phosphate ABC transporter permease PstC; |
12-230 |
9.49e-04 |
|
phosphate ABC transporter permease PstC;
Pssm-ID: 183070 Cd Length: 319 Bit Score: 40.06 E-value: 9.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 12 LAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITRG---IDGMSLA-LFTEMTPPPNTEGGGLAnALAGSG 87
Cdd:PRK11275 1 MAATKPAFNAPGKKGDIIFSALVKLAALITLLLLGGIIVSLIISSwpsIQKFGLSfLWTKEWDAPNDIYGALV-PIYGTL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 88 LLILWATVFGTPLGIMAGIYLAEYGrKSWLAEVIRFINDILLSAPSIVVG---LFVYTIVVAQM---------------- 148
Cdd:PRK11275 80 VTSFIALLIAVPVSFGIALFLTELA-PGWLKRPLGIAIELLAAIPSIVYGmwgLFVFAPLFATYfqepvgnvlsnipivg 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 149 EHFSG--------WAGVIaLALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIAR 220
Cdd:PRK11275 159 ALFSGpafgigilAAGVI-LAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPFTKNGVIGGVMLGLGR 237
|
250
....*....|
gi 447174735 221 IAGETAPLLF 230
Cdd:PRK11275 238 ALGETMAVTF 247
|
|
| PRK10971 |
PRK10971 |
sulfate/thiosulfate ABC transporter permease CysT; |
154-242 |
4.82e-03 |
|
sulfate/thiosulfate ABC transporter permease CysT;
Pssm-ID: 182873 Cd Length: 277 Bit Score: 37.81 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447174735 154 WAGV-IALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTA 232
Cdd:PRK10971 140 WLGIaVAMAFTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEFGAVIFIA 219
|
90
....*....|
gi 447174735 233 lSNQFWSTDM 242
Cdd:PRK10971 220 -GNIAWKTEV 228
|
|
| |
