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Conserved domains on  [gi|447183329|ref|WP_001260585|]
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MULTISPECIES: iron ABC transporter permease [Bacillus]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 28-338 2.46e-105

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 310.46  E-value: 2.46e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  28 SLNTGTFKIPPMDVLKSLVGLGAED-QSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTV 106
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPtADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 107 VIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIYLLAWKD-GVSSTRLILVGIAVAAGFGAVSLIFSMKMTSNDFR 185
Cdd:COG0609   81 VLAIVLGGG-------LSALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 186 FATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGG 265
Cdd:COG0609  154 SIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGP 233

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447183329 266 IGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMRTK 338
Cdd:COG0609  234 IGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 28-338 2.46e-105

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 310.46  E-value: 2.46e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  28 SLNTGTFKIPPMDVLKSLVGLGAED-QSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTV 106
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPtADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 107 VIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIYLLAWKD-GVSSTRLILVGIAVAAGFGAVSLIFSMKMTSNDFR 185
Cdd:COG0609   81 VLAIVLGGG-------LSALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 186 FATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGG 265
Cdd:COG0609  154 SIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGP 233

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447183329 266 IGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMRTK 338
Cdd:COG0609  234 IGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 20-336 6.40e-86

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 261.31  E-value: 6.40e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   20 LIISIFLISLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGIN 99
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  100 AGAGLTVVIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIYLLA-WKDGVSSTRLILVGIAVAAGFGAVSLIFSMK 178
Cdd:pfam01032  81 SGAALGAVLAILLGGS-------LSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  179 MTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGA 258
Cdd:pfam01032 154 LNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAA 233

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447183329  259 SVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMR 336
Cdd:pfam01032 234 SVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
9-338 4.39e-78

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 241.49  E-value: 4.39e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   9 KNVSVLTILVGLIISIFLISLNTGTFKIPPMDVLKSLvgLGAEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRN 88
Cdd:PRK09777   1 MKIALVIFITLALAGCALLSLRMGVIPLPWRALLTDW--QAGDEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  89 PLADPGIIGINAGAGLTVVIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIYLLAwkdGVSST-RLILVGIAVAAG 167
Cdd:PRK09777  79 PLASPDILGVNHAASLASVGALLLFPS-------LPVMWLPLLAFIGGMAGLILLKMLA---GTHQPmKLALTGVALSAL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 168 FGAVSlIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRK 247
Cdd:PRK09777 149 WASLT-DYLMLSRPQDINNALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFW 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 248 LLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGA 327
Cdd:PRK09777 228 ALLLAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGA 307

                        330
                 ....*....|.
gi 447183329 328 PYFIYLLMRTK 338
Cdd:PRK09777 308 PWFFWLLVRMR 318
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 65-334 9.54e-53

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 174.67  E-value: 9.54e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  65 MVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIY 144
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIG-------LSNYALGAFAFAGALAIALLVL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 145 LLAWKDGVSSTRLILVGIAVAAGFGAVSLIFSMKMtSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHIL 224
Cdd:cd06550   74 LLASRGGLSPSKLILIGIVLSAFFSAGVILISLLS-DDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 225 NVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFAD 304
Cdd:cd06550  153 NLLTFDEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGD 232

                        250       260       270
                 ....*....|....*....|....*....|
gi 447183329 305 VISRSVLPtSEIPVGLVISVIGAPYFIYLL 334
Cdd:cd06550  233 LLSRTLLP-SELPVGPVTALLGAPYFLYLL 261
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 53-338 9.77e-51

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 171.19  E-value: 9.77e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   53 QSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLtvvifvyfffGKVGTGTFLSVFILPFFA 132
Cdd:TIGR03869  45 QDAIVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASL----------GAVAVLVLGVAVLLPVAA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  133 LVGAILAAVIIYLLAWKDG-VSSTRLILVGIAVAAGFGAV-SLIFSMKMTSNDFRFATIWLAGSLWGTDWKFV-LSVLPW 209
Cdd:TIGR03869 115 FAGALLALAATLGLARTLGtLTPTRTILAGLAVSQLCAAVtSFVIFWSATGDSYREILSWLMGSLAGATWGSVaIAGGAL 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  210 MVIFLPLAISkAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIML 289
Cdd:TIGR03869 195 LVVGLVLLAS-GRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRHRLLL 273

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 447183329  290 PTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMRTK 338
Cdd:TIGR03869 274 PVSALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSR 322
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 28-338 2.46e-105

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 310.46  E-value: 2.46e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  28 SLNTGTFKIPPMDVLKSLVGLGAED-QSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTV 106
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPtADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 107 VIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIYLLAWKD-GVSSTRLILVGIAVAAGFGAVSLIFSMKMTSNDFR 185
Cdd:COG0609   81 VLAIVLGGG-------LSALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 186 FATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGG 265
Cdd:COG0609  154 SIVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGP 233

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447183329 266 IGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMRTK 338
Cdd:COG0609  234 IGFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 11-337 1.07e-90

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 274.69  E-value: 1.07e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  11 VSVLTILVGLIISIFLISLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPL 90
Cdd:COG4779   23 LLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSLTRNPL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  91 ADPGIIGINAGAGLTVVIFVYFFFGkvgtgtflSVFILPFFALVGAILAAVIIYLLAWKDGVSSTRLILVGIAVAAGFGA 170
Cdd:COG4779  103 ASPDIIGITAGASAGAVAAIVVLGG--------SGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 171 VSLIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLF 250
Cdd:COG4779  175 VNSYLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLL 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 251 IAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGkHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYF 330
Cdd:COG4779  255 VAVALAAVATAAAGPIAFVALAAPQIARRLTRS-PGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYL 333


                 ....*..
gi 447183329 331 IYLLMRT 337
Cdd:COG4779  334 LWLLIRE 340
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 20-336 6.40e-86

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 261.31  E-value: 6.40e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   20 LIISIFLISLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGIN 99
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  100 AGAGLTVVIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIYLLA-WKDGVSSTRLILVGIAVAAGFGAVSLIFSMK 178
Cdd:pfam01032  81 SGAALGAVLAILLGGS-------LSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  179 MTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGA 258
Cdd:pfam01032 154 LNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAA 233

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447183329  259 SVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMR 336
Cdd:pfam01032 234 SVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
9-338 4.39e-78

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 241.49  E-value: 4.39e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   9 KNVSVLTILVGLIISIFLISLNTGTFKIPPMDVLKSLvgLGAEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRN 88
Cdd:PRK09777   1 MKIALVIFITLALAGCALLSLRMGVIPLPWRALLTDW--QAGDEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  89 PLADPGIIGINAGAGLTVVIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIYLLAwkdGVSST-RLILVGIAVAAG 167
Cdd:PRK09777  79 PLASPDILGVNHAASLASVGALLLFPS-------LPVMWLPLLAFIGGMAGLILLKMLA---GTHQPmKLALTGVALSAL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 168 FGAVSlIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRK 247
Cdd:PRK09777 149 WASLT-DYLMLSRPQDINNALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFW 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 248 LLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGA 327
Cdd:PRK09777 228 ALLLAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGA 307

                        330
                 ....*....|.
gi 447183329 328 PYFIYLLMRTK 338
Cdd:PRK09777 308 PWFFWLLVRMR 318
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
52-337 5.71e-74

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 240.90  E-value: 5.71e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  52 DQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGkvgtgtfLSVFILPFF 131
Cdd:PRK10577 388 QLLDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPG-------AGFGWLLAA 460

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 132 ALVGAILAAVIIYLLAWKDGVSSTRLILVGIAVAAGFGAVSlifSMKMTSNDFRFATI--WLAGSLWGTDWKFVLSVLPW 209
Cdd:PRK10577 461 ALLGALAALALILLLARRGGFAPERLLLTGIALSALFTALI---QLLLASGDPRAAQLltWLSGSTYGVTWAQALPLLIV 537

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 210 MVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIML 289
Cdd:PRK10577 538 AVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQL 617

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 447183329 290 PTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMRT 337
Cdd:PRK10577 618 VLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRS 665
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 8-338 1.21e-61

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 199.80  E-value: 1.21e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   8 KKNVSVLTILVGLIISIFLISLNTGTFKIPPMDVLkslvglgAEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSR 87
Cdd:PRK03784  12 RRNRRWLLGLSVLLLLALLLSLCAGEQWISPGDWL-------SPRGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  88 NPLADPGIIGINAGAGLTVVIFVYFFFGkvgtgtFLSVFILPFFALVGAILAAVIIYLLAWKDGVSSTRLILVGIAVAAG 167
Cdd:PRK03784  85 NPLAEPGLLGVSNGAGVALVAAVLLGQG------LLPPWALSLCAIAGALLITLILLRFARRHRLSTSRLLLAGVALGII 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 168 FGAV---SLIFSmkmTSNDFRFATIWLAGSLWGTDWKFVLsvlpWMVIFLPLAI---SKAHILNVMNLGDSTAVGLGVNV 241
Cdd:PRK03784 159 CSALmtwAVYFS---TSLDLRQLMYWMMGGFGGVDWRQSW----LMLALLPVLIwlcCQGRPLNMLALGEISARQLGLPL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 242 EKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLV 321
Cdd:PRK03784 232 WFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLALASAELPIGVV 311

                        330
                 ....*....|....*..
gi 447183329 322 ISVIGAPYFIYLLMRTK 338
Cdd:PRK03784 312 TATLGAPVFIWLLLRSH 328
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 14-338 1.60e-61

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 199.31  E-value: 1.60e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  14 LTILVGLIISIFLISLNTGTFKIPPMDVLKslvglgaEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADP 93
Cdd:COG4139   15 LLLLLLLLLLLFVLSLCAGEVWIPPTQWLS-------EAWQLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  94 GIIGINAGAGLTVVIFVYFFfgkvgtGTFLSVFILPFFALVGAILAAVIIYLLAWKdGVSSTRLILVGIAVAAGFGAVSL 173
Cdd:COG4139   88 GLLGISNGAGVGLVLVVLLG------GGLLPPWLLSLAAIAGALLVTLLLLAFARR-RLSNARLLLIGVALGIICSAIMT 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 174 IFSMKMTSNDFRFATIWLAGSLWGTDWkfvlSVLPWMVIFLP---LAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLF 250
Cdd:COG4139  161 WAVYFSSSLDLRQLMYWMMGSFGGVDW----RQLWLLLALLPvllWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLVL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 251 IAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYF 330
Cdd:COG4139  237 ATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARLALSSAELPIGVVTATLGAPVF 316


                 ....*...
gi 447183329 331 IYLLMRTK 338
Cdd:COG4139  317 IWLLLRRR 324
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-338 2.03e-59

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 201.99  E-value: 2.03e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   1 MRTSILTKKNVSVLTILVGLIISIFLISLNTGTFKIPPMDVLKSLVGLGAED-QSVILFEFRMPRMVIAILVGSALAMSG 79
Cdd:PRK10577   1 MPRLMSRRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDlEQLLLHYSRLPRLAIALLVGAALGLAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  80 AILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGKVGTGTFLsvfilpfFALVGAILAAVIIYLLAWKDGVSSTRLIL 159
Cdd:PRK10577  81 ALLQQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQL-------AAFAGGLLAAALVFALAGGKRLSPLRLVL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 160 VGIAVAAGFGAVS---LIFSMKMTSNDFrfatIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVG 236
Cdd:PRK10577 154 AGMVVSLYLGALTtllLLFNEQYLQGLF----LWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARS 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 237 LGVNVEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTS-- 314
Cdd:PRK10577 230 LGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVGge 309

                        330       340
                 ....*....|....*....|....
gi 447183329 315 EIPVGLVISVIGAPYFIYLLMRTK 338
Cdd:PRK10577 310 LLPTGAVTALIGAPLLLWLLPRLR 333
btuC PRK09535
cobalamin ABC transporter permease BtuC;
50-336 3.22e-57

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 189.58  E-value: 3.22e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  50 AEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTVVIFVYFffgkvgtgTFLSVFILP 129
Cdd:PRK09535  84 PETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVL--------PLAVPFGLQ 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 130 FFALVGAILAAVIIYLLAWKDGVSST-RLILVGIAVAAGFGAVsLIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLP 208
Cdd:PRK09535 156 AAAFAGALVAAFGVYAIATENGRTPVaTLLLAGVAVQTFLGAV-ISYLLLHSGESLRRAVYWLMGHLHGSTWSDVEVALP 234

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 209 WMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIM 288
Cdd:PRK09535 235 VVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRIL 314

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 447183329 289 LPTAALIGTFLLLFADVISRSvlPTSEIPVGLVISVIGAPYFIYLLMR 336
Cdd:PRK09535 315 LPTSALAGASFLVATDTVARS--GPAEVPVGIVTAALGAPFFLYLLRT 360
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
16-336 4.49e-55

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 182.60  E-value: 4.49e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  16 ILVGLIISIFLISLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGI 95
Cdd:PRK10440  14 LLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDV 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  96 IGINAGAGLTVVIFVYFFFGkvgtgtflSVFILPFFALVGAILAAVIIYLLAWKDGVSSTRLILVGIAVAAGFGAVSLIF 175
Cdd:PRK10440  94 MGFNTGAWSGVLVAMVLFGQ--------DLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 176 SMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCL 255
Cdd:PRK10440 166 LLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLVAVVL 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 256 AGASVAVAGGIGFIGLMAPHLARRLVGGKhQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLM 335
Cdd:PRK10440 246 TAAATALAGPISFIALVAPHIARRLSGTA-RWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLI 324


                 .
gi 447183329 336 R 336
Cdd:PRK10440 325 Q 325
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
16-336 5.62e-54

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 179.89  E-value: 5.62e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  16 ILVGLIISIFLISLNT-GTFKIPPMDVLKSLV-GLGAEDQSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADP 93
Cdd:PRK11228   4 LPVAALIGLFWLSLFCySAIPISAADALNALLpGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  94 GIIGINAGAGLTVVIFVYFffgkvgTGTFLSVFILPFFALVGAILAAVIIYLL--AWKDGVSSTRLILVGIAVAAGFGAV 171
Cdd:PRK11228  84 SLLGINSGAALAMALTSAL------SPTPFAGYSLAFIAACGGGLSWLLVMTAggGWRHTHDRNRLILAGIALSALCMAL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 172 SLIFSMKMTSNDFRFATiWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVNVEKERRKLLFI 251
Cdd:PRK11228 158 TRITLLLAEDHAYGIFY-WLAGGVSHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNML 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 252 AVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFI 331
Cdd:PRK11228 237 VLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFV 316


                 ....*
gi 447183329 332 YLLMR 336
Cdd:PRK11228 317 WLARR 321
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 65-334 9.54e-53

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 174.67  E-value: 9.54e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  65 MVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGkvgtgtfLSVFILPFFALVGAILAAVIIY 144
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIG-------LSNYALGAFAFAGALAIALLVL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 145 LLAWKDGVSSTRLILVGIAVAAGFGAVSLIFSMKMtSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHIL 224
Cdd:cd06550   74 LLASRGGLSPSKLILIGIVLSAFFSAGVILISLLS-DDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 225 NVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFAD 304
Cdd:cd06550  153 NLLTFDEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGD 232

                        250       260       270
                 ....*....|....*....|....*....|
gi 447183329 305 VISRSVLPtSEIPVGLVISVIGAPYFIYLL 334
Cdd:cd06550  233 LLSRTLLP-SELPVGPVTALLGAPYFLYLL 261
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 53-338 9.77e-51

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 171.19  E-value: 9.77e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   53 QSVILFEFRMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLtvvifvyfffGKVGTGTFLSVFILPFFA 132
Cdd:TIGR03869  45 QDAIVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASL----------GAVAVLVLGVAVLLPVAA 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  133 LVGAILAAVIIYLLAWKDG-VSSTRLILVGIAVAAGFGAV-SLIFSMKMTSNDFRFATIWLAGSLWGTDWKFV-LSVLPW 209
Cdd:TIGR03869 115 FAGALLALAATLGLARTLGtLTPTRTILAGLAVSQLCAAVtSFVIFWSATGDSYREILSWLMGSLAGATWGSVaIAGGAL 194

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  210 MVIFLPLAISkAHILNVMNLGDSTAVGLGVNVEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIML 289
Cdd:TIGR03869 195 LVVGLVLLAS-GRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRHRLLL 273

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 447183329  290 PTAALIGTFLLLFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMRTK 338
Cdd:TIGR03869 274 PVSALAGAVFLVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSR 322
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
1-336 1.06e-47

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 163.72  E-value: 1.06e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329   1 MRTSILTKKNVSVLTILVGLIISIFLiSLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEFRMPRMVIAILVGSALAMSGA 80
Cdd:PRK10441   1 MSGSVAVTRAIAVPGLLLLLIIATAL-SLLIGAKSLPASVVLEALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329  81 ILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFfgkvgtgTFLSVFILPFFALVGAILAAVIIYLLAWKDG--VSSTRLI 158
Cdd:PRK10441  80 LMQTLTRNPLADPGLLGVNAGASFAIVLGAALF-------GYSSAQEQLAMAFAGALVASLIVAFTGSQGGgqLSPVRLT 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 159 LVGIAVAAGFGAVSLIFSM--KMTSNDFRFatiWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVG 236
Cdd:PRK10441 153 LAGVALAAVLEGLTSGIALlnPDVYDQLRF---WQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATA 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447183329 237 LGVNVEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPtSEI 316
Cdd:PRK10441 230 LGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLVP-GEL 308

                        330       340
                 ....*....|....*....|
gi 447183329 317 PVGLVISVIGAPYFIYLLMR 336
Cdd:PRK10441 309 RVSVVSAFIGAPVLIFLVRR 328
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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