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Conserved domains on  [gi|447196544|ref|WP_001273800|]
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MULTISPECIES: TIGR02594 family protein [Enterobacteriaceae]

Protein Classification

C40 family peptidase( domain architecture ID 229557)

C40 family peptidase is a cell-wall hydrolase that cleaves peptide cross-bridges between glycan chains and is essential for bacterial growth and viability; typically cleaves the linkage between D-Glu and diaminopimelic acid (or Lys) within peptidoglycan stem peptides; contains a Cys-His-His catalytic triad

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NLPC_P60 super family cl21534
NlpC/P60 family; The function of this domain is unknown. It is found in several lipoproteins.
 8-138 2.99e-33

NlpC/P60 family; The function of this domain is unknown. It is found in several lipoproteins.


The actual alignment was detected with superfamily member TIGR02594:

Pssm-ID: 473902  Cd Length: 129  Bit Score: 114.09  E-value: 2.99e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447196544    8 WLIEARKHIGLTEIKGAKHNPEIVQFwrdikRGGIKDDETPWCAAFVGAMLERVGIRSTRFES-AKSYLDWGEKLDTPAY 86
Cdd:TIGR02594   2 WVKEARKYIGVKEIKGGKNNPRIVEY-----NKVRTDDETPWCGSFVNMCLEKTGRKGTGNSAmARSWARYGTKLSKPAY 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 447196544   87 GCIVVFTRVGGGHVGFVVGRRAN-GDLLVLGGNQGDAVNIRAFPTSRVSGYRW 138
Cdd:TIGR02594  77 GCIAVKRRGGGGHVGFVVGKDKQtGTIIVLGGNQGDRVREALYSRSRIVAYRW 129
 
Name Accession Description Interval E-value
TIGR02594 TIGR02594
TIGR02594 family protein; Members of this protein family known so far are restricted to the ...
 8-138 2.99e-33

TIGR02594 family protein; Members of this protein family known so far are restricted to the bacteria, and for the most to the proteobacteria. The function is unknown.


Pssm-ID: 131643  Cd Length: 129  Bit Score: 114.09  E-value: 2.99e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447196544    8 WLIEARKHIGLTEIKGAKHNPEIVQFwrdikRGGIKDDETPWCAAFVGAMLERVGIRSTRFES-AKSYLDWGEKLDTPAY 86
Cdd:TIGR02594   2 WVKEARKYIGVKEIKGGKNNPRIVEY-----NKVRTDDETPWCGSFVNMCLEKTGRKGTGNSAmARSWARYGTKLSKPAY 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 447196544   87 GCIVVFTRVGGGHVGFVVGRRAN-GDLLVLGGNQGDAVNIRAFPTSRVSGYRW 138
Cdd:TIGR02594  77 GCIAVKRRGGGGHVGFVVGKDKQtGTIIVLGGNQGDRVREALYSRSRIVAYRW 129
 
Name Accession Description Interval E-value
TIGR02594 TIGR02594
TIGR02594 family protein; Members of this protein family known so far are restricted to the ...
 8-138 2.99e-33

TIGR02594 family protein; Members of this protein family known so far are restricted to the bacteria, and for the most to the proteobacteria. The function is unknown.


Pssm-ID: 131643  Cd Length: 129  Bit Score: 114.09  E-value: 2.99e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447196544    8 WLIEARKHIGLTEIKGAKHNPEIVQFwrdikRGGIKDDETPWCAAFVGAMLERVGIRSTRFES-AKSYLDWGEKLDTPAY 86
Cdd:TIGR02594   2 WVKEARKYIGVKEIKGGKNNPRIVEY-----NKVRTDDETPWCGSFVNMCLEKTGRKGTGNSAmARSWARYGTKLSKPAY 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 447196544   87 GCIVVFTRVGGGHVGFVVGRRAN-GDLLVLGGNQGDAVNIRAFPTSRVSGYRW 138
Cdd:TIGR02594  77 GCIAVKRRGGGGHVGFVVGKDKQtGTIIVLGGNQGDRVREALYSRSRIVAYRW 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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