|
Name |
Accession |
Description |
Interval |
E-value |
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
4-930 |
0e+00 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 1533.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 4 YKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKG 83
Cdd:COG0060 1 YKETLNLPKTDFPMRANLPKREPEILKFWEENDIYEKSREARAGRPKFVLHDGPPYANGDIHIGHALNKILKDIIVRYKT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 84 LSGYDSPYVPGWDCHGLPIELKVEQEYGKPG---EKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK 160
Cdd:COG0060 81 MRGFDVPYVPGWDCHGLPIELKVEKELGIKKkdiEKVGIAEFREKCREYALKYVDEQREDFKRLGVWGDWDNPYLTMDPE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 161 TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDQDALKAkfavsnvNGPISLVIW 240
Cdd:COG0060 161 YEESIWWALKKLYEKGLLYKGLKPVPWCPRCGTALAEAEVEYKDVTSPSIYVKFPVKDEKALLL-------LEDAYLVIW 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 241 TTTPWTLPANRAISIAPDFDYALVQI-DGQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGF-----D 314
Cdd:COG0060 234 TTTPWTLPANLAVAVHPDIDYVLVEVtGGERLILAEALVEAVLKELGIEDYEVLATFKGAELEGLRYEHPFYYVvgydrA 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 315 VPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTyPTLDGVNVFKANDIVVALLQEKGALL 394
Cdd:COG0060 314 HPVILGDYVTTEDGTGIVHTAPGHGEDDFEVGKKYGLPVLNPVDDDGRFTEEA-PLFAGLFVKDANPAIIEDLKERGALL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 395 HVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQkgLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPM 474
Cdd:COG0060 393 AREKITHSYPHCWRCKTPLIYRATPQWFISMDK--LRDRALEAIEKVNWIPEWGEGRFGNMLENRPDWCISRQRYWGVPI 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 475 SLFVHKDTEELHpRTLELMEEVAKRVEVDGIQAWWDLDAKE-ILGDE------ADQYVKVPDTLDVWFDSGSTHSSVVDV 547
Cdd:COG0060 471 PIWVCEDCGELH-RTEEVIGSVAELLEEEGADAWFELDLHRpFLDETlkcpkcGGTMRRVPDVLDVWFDSGSMHFAVLEN 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 548 RPEFaGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRL 627
Cdd:COG0060 550 REEL-HFPADFYLEGSDQTRGWFYSSLLTSTALFGRAPYKNVLTHGFVLDEDGRKMSKSLGNVVDPQEVIDKYGADILRL 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 628 WVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILNAYEAYD 707
Cdd:COG0060 629 WVASSDYWGDLRFSDEILKEVRDVYRRLRNTYRFLLANLDDFDPAEDAVPYEDLPELDRWILSRLNELIKEVTEAYDNYD 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 708 FHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVF 787
Cdd:COG0060 709 FHRAYRALHNFCVEDLSNWYLDISKDRLYTEAADSLDRRAAQTTLYEVLETLVRLLAPILPFTAEEIWQNLPGEAEESVH 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 788 TGEWYEGLFGLADSEamNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALGDELRFVLLTSG 867
Cdd:COG0060 789 LADWPEVDEELIDEE--LEAKWDLVREVRSAVLKALEAARKEKLIRQPLEAAVVLYADEELAAALESLGDLLAEELNVSE 866
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 447209609 868 ATVADY-NDAPADAQQSEVLKG--LKVALSKAEGEKCPRCWHYTrdVGKVAEHAEICGRCVSNVAG 930
Cdd:COG0060 867 VELVDDaEDLGKDALKALDVEGisVTVEVEKADGEKCERCWHYE--VGWTPEHEGLCRRCVRRVQG 930
|
|
| ileS |
TIGR00392 |
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ... |
14-843 |
0e+00 |
|
isoleucyl-tRNA synthetase; The isoleucyl tRNA synthetase (IleS) is a class I amino acyl-tRNA ligase and is particularly closely related to the valyl tRNA synthetase. This model may recognize IleS from every species, including eukaryotic cytosolic and mitochondrial forms. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273054 [Multi-domain] Cd Length: 861 Bit Score: 1172.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 14 GFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVP 93
Cdd:TIGR00392 1 KFPMRGNLSKREEKILAFWQENDIFEKVKKLNKGKPEFIFHDGPPYANGSIHLGHALNKILKDIILRYKTMQGFNVTRKP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 94 GWDCHGLPIELKVEQEYGKPG----EKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRAL 169
Cdd:TIGR00392 81 GWDTHGLPIEHKVEKKLGISGkkeiSSLEIEEFREKCREFALKQIEEQREQFQRLGVWGDWENPYKTMDPSYEESQWWLF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 170 GKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYY----DKTSPSIDVAFQAVDQDALKAKFAVSnvngpiSLVIWTTTPW 245
Cdd:TIGR00392 161 KEAHEKGLLYRGLKPVYWSPRCRTALAEAEVEYKenykDVKDPSIYVKFPVKKDKKTYLKVKLS------SLLIWTTTPW 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 246 TLPANRAISIAPDFDYALVQIDG--QAVILAKDLVESVMQRIGVtDYTILGTVKGAELELLRFTHPFMGFDVP------- 316
Cdd:TIGR00392 235 TLPSNLAIAVHPDFEYALVQDNTkvEYFILAKKLVEKLYNKAGS-DYEIIKTFKGSDLEGLEYEHPLYDFVSQlkegapv 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 317 AILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYP------TLDGVNVFKANDIVVALLQEK 390
Cdd:TIGR00392 314 VIGGDHVTTEDGTGIVHTAPGHGEEDYEIGKKYGLEVLSPVDEKGVYTEGVNDfqgrfvKDADKDIIKANKIIIEQLKDK 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 391 GALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMdqKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTW 470
Cdd:TIGR00392 394 GLLLKAEKITHSYPHCWRTKTPVIYRATEQWFIKT--KDIKDQMLEQIKKVNWVPEWGEGRFGNWLENRPDWCISRQRYW 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 471 GVPMSLFVHKDTEElhPRTLELMEEVAKRVEVDGIQAWWDLDAKEILGD------EADQYVKVPDTLDVWFDSGSTHSSV 544
Cdd:TIGR00392 472 GIPIPIWYCEDTGE--PIVVGSIEELIELIELKGIDAWFEDLHRDFLDKitlksgDGGEYRRVPDVLDVWFDSGSMPYAS 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 545 VDVRPE----FAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKL 620
Cdd:TIGR00392 550 IHYPFEnekfKEVFPADFILEGSDQTRGWFYSSLAIGTALFGQAPYKNVITHGFTLDEKGRKMSKSLGNVVDPLKVINKY 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 621 GADILRLWVASTDYTGEMAVSDEILKRAADSYRRIR-NTARFLL--ANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQE 697
Cdd:TIGR00392 630 GADILRLYVASSDPWEDLRFSDEILKQVVEKYRKIRwNTYRFLLtyANLDKFDPLFNSVAVEKFPEEDRWILSRLNSLVE 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 698 DILNAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVArRSCQTALYHIAEALVRWMAPILSFTADEVWGY 777
Cdd:TIGR00392 710 EVNEALEKYNFHKVLRALQDFIVEELSNWYIRIIRDRLYCEAKDNDK-RAAQTTLYYALLTLVRLLAPFLPHTAEEIYQN 788
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 447209609 778 LPGER-EKYVFTGEWYEG-----LFGLADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLY 843
Cdd:TIGR00392 789 LPGGEeEESVHLNLWPEVdeefiDEALEANMAIVREIVEAFLALRDAANKKLRQPLKELVIGKSLEAVLKAV 860
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
17-929 |
0e+00 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 932.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 17 MRGDLAKREPGMLARWTDDDLYGIIRAAKKGKkTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWD 96
Cdd:PLN02843 1 MRANSVTREPEIQKLWEENQVYKRVSDRNNGE-SFTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 97 CHGLPIELKVEQEY-GKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGN 175
Cdd:PLN02843 80 CHGLPIELKVLQSLdQEARKELTPIKLRAKAAKFAKKTVDTQRESFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 176 GHLHKGAKPVHWCVDCRSALAEAEVEYYD-KTSPSIDVAFQAVDqDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAIS 254
Cdd:PLN02843 160 GYIYRGRKPVHWSPSSRTALAEAELEYPEgHVSKSIYVAFPVVS-PSETSPEELEEFLPGLSLAIWTTTPWTMPANAAVA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 255 IAPDFDYALVQIDGQA-------------------------VILAKDLVESVMQRIGVTdYTILGTVKGAELELLRFTHP 309
Cdd:PLN02843 239 VNDKLQYSVVEVQSFSedestsggnkkkrpgnvlkeqqklfLIVATDLVPALEAKWGVK-LVVLKTFPGSDLEGCRYIHP 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 310 FMGFDVPAIL-GDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPtLDGVNVFKA-NDIVVALL 387
Cdd:PLN02843 318 LYNRESPVVIgGDYITTESGTGLVHTAPGHGQEDYITGLKYGLPLLSPVDDAGKFTEEAGQ-FSGLSVLGEgNAAVVEAL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 388 QEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDqkGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQ 467
Cdd:PLN02843 397 DEAGSLLMEEAYGHKYPYDWRTKKPTIFRATEQWFASVE--GFRQAALDAIDKVKWIPAQGENRIRAMVSGRSDWCISRQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 468 RTWGVPMSLFVHKDTEE--LHPRTLELMEEVakrVEVDGIQAWWDLDAKEIL----GDEADQYVKVPDTLDVWFDSGSTH 541
Cdd:PLN02843 475 RTWGVPIPVFYHVETKEplMNEETIAHVKSI---VAQKGSDAWWYMDVEDLLpekyRDKASDYEKGTDTMDVWFDSGSSW 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 542 SSVVDVRPEFAgHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVM---- 617
Cdd:PLN02843 552 AGVLGSREGLS-YPADLYLEGSDQHRGWFQSSLLTSVATKGKAPYKSVLTHGFVLDEKGFKMSKSLGNVVDPRLVIeggk 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 618 NK-----LGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPaKDMVKPEEMVVLDRWAVGCA 692
Cdd:PLN02843 631 NQkqepaYGADVLRLWVASVDYTGDVLIGPQILKQMSDIYRKLRGTLRYLLGNLHDWKP-DNAVPYEDLPSIDKYALFQL 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 693 KAAQEDILNAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTAD 772
Cdd:PLN02843 710 ENVVNEIEESYDNYQFFKIFQILQRFTIVDLSNFYLDVAKDRLYVGGTTSFTRRSCQTVLAAHLLSLLRAIAPILPHLAE 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 773 EVWGYLP----GEREKYVFTGEWYEGL---FGLADSEAmndAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYA- 844
Cdd:PLN02843 790 DAWQNLPfqedGSAAESVFEAGWPTPNeewLSFPAEDV---DFWSLLLEVRDEVNKVLESARNGKLIGASLEAKVYLHAs 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 845 EPELAAKLTAL------GDELRFVLLTSGATVADYND---APADAQQSEVLKG---LKVALSKAEGEKCPRCWHYTRDVG 912
Cdd:PLN02843 867 DASLAARLAELcgasngADELRRIFITSQVEVVSSEDdetAACGSYTGEYVEGagrVWVGVSRADGSKCERCWNYSPAVG 946
|
970
....*....|....*..
gi 447209609 913 KVAEHAEICGRCVSNVA 929
Cdd:PLN02843 947 SFSDHPTLCERCYPVVI 963
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
27-641 |
0e+00 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 895.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 27 GMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKV 106
Cdd:pfam00133 1 QIYEFWDEQGYFKPELEKRKGKPSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTEQVV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 107 EQEYGKPGE----KFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGA 182
Cdd:pfam00133 81 EKKLGIKEKktrhKYGREEFREKCREWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIYRGK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 183 KPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDQDAlkakfavsnvngpISLVIWTTTPWTLPANRAISIAPDFDYA 262
Cdd:pfam00133 161 KLVNWSPALNTALSNLEVEYKDVKGPSIHVAFPLADDEG-------------ASLVIWTTTPWTLPGNTAVAVNPEFDYV 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 263 lvqIDGQAVILAKDLVESVMQRIgvTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDD 342
Cdd:pfam00133 228 ---ITGEGYILAEALLKSLYKKG--TDKKILEDFRGKELEGKEAIHPFVNREIPIITDDYVDMEFGTGAVHIAPAHGEND 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 343 YVIGQKYGLETANPVGPDGTYLPGTyPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWF 422
Cdd:pfam00133 303 YEVGQRHNLEVINPVDDDGTFTEEA-PDFQGVYRFDARKKIVELLTEKGLLLKIEPFTHSYPFCWRSGTPIIPRATPQWF 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 423 VSMDQkgLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTlELMEEVAKRVEV 502
Cdd:pfam00133 382 VRMDE--LADQALEAVEKVQFVPKSGEKRYFNWLANIQDWCISRQRWWGHPIPAWVSKDTEEVVCRG-ELFELVAGRFEE 458
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 503 DGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVD----VRPEFA-GHAADMYLEGSDQHRGWFMSSLMIS 577
Cdd:pfam00133 459 EGSIKWLHREAKDKLGYGKGTLEQDEDVLDTWFSSGSWPFSTLGwpfvNTEEFKkFFPADMLLEGSDQTRGWFYRMIMLS 538
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447209609 578 TAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVS 641
Cdd:pfam00133 539 TALTGSVPFKNVLVHGLVRDEQGRKMSKSLGNVIDPLDVIDKYGADALRLWLANSDYGRDINLS 602
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
49-640 |
6.69e-121 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 371.18 E-value: 6.69e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 49 KTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPG----EKFTAAEFRA 124
Cdd:cd00818 1 PEFVFHDGPPYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIELKVEKELGISGkkdiEKMGIAEFNA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 125 KCREYaatqvdgqrkdfirlgvlgdwshpyltmdfkteaniiralgkiignghlhkgakpvhwcvdcrsalaeaeveyyd 204
Cdd:cd00818 81 KCREF--------------------------------------------------------------------------- 85
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 205 ktspsidvafqavdqdalkakfavsnvngpislviwtttpwtlpanraisiapdfdyALVQIDGQavilakdlvESVMQR 284
Cdd:cd00818 86 ---------------------------------------------------------ALRYVDEQ---------EEQFQR 99
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 285 IGVtdytilgtvkgaeleLLRFTHPFMgfdvpailgdhvTLDagtgavhtapghgpDDYVIGQkygletanpvgpdgtyl 364
Cdd:cd00818 100 LGV---------------WVDWENPYK------------TMD--------------PEYMESV----------------- 121
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 365 pgtyptldgVNVFKAndivvalLQEKGaLLHvekmQHSYPCCWrhktPIIFRATPQWFVSMDqkGLRAQSLKEIKGVQWI 444
Cdd:cd00818 122 ---------WWVFKQ-------LHEKG-LLY----RGYKVVPW----PLIYRATPQWFIRVT--KIKDRLLEANDKVNWI 174
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 445 PDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRtlelmeevakrvevdgiqawwdldakeilgdeadqy 524
Cdd:cd00818 175 PEWVKNRFGNWLENRRDWCISRQRYWGTPIPVWYCEDCGEVLVR------------------------------------ 218
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 525 vKVPDTLDVWFDSGSTHSSVVDVRPE----FAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQG 600
Cdd:cd00818 219 -RVPDVLDVWFDSGSMPYAQLHYPFEnedfEELFPADFILEGSDQTRGWFYSLLLLSTALFGKAPYKNVIVHGFVLDEDG 297
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 447209609 601 RKMSKSIGNTVSPQDVMNKLGADILRLWVASTD-YTGEMAV 640
Cdd:cd00818 298 RKMSKSLGNYVDPQEVVDKYGADALRLWVASSDvYAEDLRF 338
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
11-857 |
1.22e-109 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 356.81 E-value: 1.22e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 11 PETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKgkKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSP 90
Cdd:PRK13208 2 MMPELPKKYDPEELEEKWQKIWEEEGTYKFDPDERK--PVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 91 YVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMD----FKTEANII 166
Cdd:PRK13208 80 FPQGWDDNGLPTERKVEKYYGIRKDDISREEFIELCRELTDEDEKKFRELWRRLGLSVDWSLEYQTISpeyrRISQKSFL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 167 RALGKiignGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDqdalkakfavsnvNGPIslVIWTTTPWT 246
Cdd:PRK13208 160 DLYKK----GLIYRAEAPVLWCPRCETAIAQAEVEYREREGKLNYIKFPVED-------------GEEI--EIATTRPEL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 247 LPANRAISIAPDFD-YalvqidgqavilaKDLVesvmqrigvtdytilGTvkgaelellRFTHPFMGFDVPaILGDH-VT 324
Cdd:PRK13208 221 LPACVAVVVHPDDErY-------------KHLV---------------GK---------TAIVPLFGVEVP-ILADPlVD 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 325 LDAGTGAV-------HTapghgpdDYVIGQKYGLETANPVGPDGTYLPgTYPTLDGVNVFKANDIVVALLQEKGALLHVE 397
Cdd:PRK13208 263 PDFGTGAVmictfgdKT-------DVTWWRELNLPTRIIIDEDGRMTE-AAGKLAGLTIEEARKKIVEDLKSGGLLGKQE 334
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 398 KMQHSYPCCWRHKTPIIFRATPQWFVsmDQKGLRAQSLKEIKGVQWIPDWGQAR----IESMvanRPDWCISRQRTWGVP 473
Cdd:PRK13208 335 PIKHNVKFCERCDTPLEILVTRQWFI--KVLDLKEELLERGKEINWYPEHMRVRlenwIEGL---NWDWCISRQRYFGTP 409
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 474 MSLFVHKDTEELHprtlelmeeVAKRVEVDgIQAWWDL---DAKEILGdeADQYVKVPDTLDVWFDSGST--HSSVVDVR 548
Cdd:PRK13208 410 IPVWYCKDCGHPI---------LPDEEDLP-VDPTKDEppgYKCPQCG--SPGFEGETDVMDTWATSSITplIVTGWERD 477
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 549 PEFAGHA--ADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILR 626
Cdd:PRK13208 478 EDLFEKVfpMDLRPQGHDIIRTWLFYTILRAYLLTGKLPWKNIMISGMVLDPDGKKMSKSKGNVVTPEELLEKYGADAVR 557
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 627 LWVAS----TDYtgemAVSDEILKRAADSYRRIRNTARFLLanlnGFDPAKDMVKPEEMVVLDRWAVgcAKAAQ--EDIL 700
Cdd:PRK13208 558 YWAASarlgSDT----PFDEKQVKIGRRLLTKLWNASRFVL----HFSADPEPDKAEVLEPLDRWIL--AKLAKvvEKAT 627
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 701 NAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYtAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLpg 780
Cdd:PRK13208 628 EALENYDFAKALEEIESFFWHVFCDDYLELVKSRAY-GEDEEEEQKSARYTLYTVLDTLLRLLAPFLPFITEEVWSWL-- 704
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 781 eREKYVFTGEWYEGLFGLADSEAmndafwDELLKVRGEVNKVIEQARADKKVggSLEA---AVTLYAEPELAAKLTALGD 857
Cdd:PRK13208 705 -YGGSVHRASWPEPDEELIDEED------EELGELAKEILSAVRKYKSEAGL--SLNAplkKVEVYGPADLELLEAAEED 775
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
15-779 |
1.54e-109 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 358.22 E-value: 1.54e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 15 FPMRGDLAKREPGMLARWTDDDLYGIIraAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPG 94
Cdd:TIGR00422 1 MPKDYDPHEVEKKWYKKWEKSGFFKPD--GNSNKPPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 95 WDCHGLPIELKVEQEYGKPGEK---FTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGK 171
Cdd:TIGR00422 79 TDHAGIATQVKVEKKLGAEGKTkhdLGREEFREKIWEWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKEAFVR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 172 IIGNGHLHKGAKPVHWCVDCRSALAEAEVEYydktspsidvafQAVDQDALKAKFAVSNvNGPISLVIWTTTPWTLPANR 251
Cdd:TIGR00422 159 LYEKGLIYRGEYLVNWDPKLNTAISDIEVEY------------KEVKGKLYYIRYPLAN-GSKDYLVVATTRPETMFGDT 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 252 AISIAPDFD-YalvqidgqavilaKDLVesvmqrigvtdytilgtvkGAElellrFTHPFMGFDVPAILGDHVTLDAGTG 330
Cdd:TIGR00422 226 AVAVHPEDErY-------------KHLI-------------------GKK-----VILPLTGRKIPIIADEYVDMEFGTG 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 331 AVHTAPGHGPDDYVIGQKYGLETANPVGPDGtYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHK 410
Cdd:TIGR00422 269 AVKVTPAHDFNDYEWGKRHNLEFINILDEDG-LLNENAGKYQGLTRFEARKKIVEDLKEEGLLVKIEPHTHNVGTCWRSG 347
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 411 TPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHprtl 490
Cdd:TIGR00422 348 TVVEPLLSKQWFVKVEKLADKALEAAEEGEIKFVPKRMEKRYLNWLRNIKDWCISRQLIWGHRIPVWYCKECGEVY---- 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 491 elmeeVAKRVevdgiqawwDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVV---DVRPEFAG-HAADMYLEGSDQH 566
Cdd:TIGR00422 424 -----VAKEE---------PLPDDKTNTGPSVELEQDTDVLDTWFSSSLWPFSTLgwpDETKDLKKfYPTDLLVTGYDII 489
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 567 RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTG-EMAVSDEIL 645
Cdd:TIGR00422 490 FFWVARMIFRSLALTGQVPFKEVYIHGLVRDEQGRKMSKSLGNVIDPLDVIEKYGADALRFTLASLVTPGdDINFDWKRV 569
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 646 KRAADSYRRIRNTARFLLANLNGfdpAKDMVKPEEMV-VLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSVEMG 724
Cdd:TIGR00422 570 ESARNFLNKLWNASRFVLMNLSD---DLELSGGEEKLsLADRWILSKLNRTIKEVRKALDKYRFAEAAKALYEFIWNDFC 646
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*
gi 447209609 725 SFYLDIIKDRQYTAKADsvARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLP 779
Cdd:TIGR00422 647 DWYIELVKYRLYNGNEA--EKKAARDTLYYVLDKALRLLHPFMPFITEEIWQHFK 699
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
20-769 |
1.32e-98 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 334.77 E-value: 1.32e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 20 DLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHG 99
Cdd:PLN02882 9 SFPKQEEKILSLWSEIDAFKTQLKRTEGLPEYIFYDGPPFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTRRFGWDCHG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 100 LPIELKVEQEYGKPGE----KFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGN 175
Cdd:PLN02882 89 LPVEYEIDKKLGIKRRddvlKMGIDKYNEECRSIVTRYSKEWEKTVTRTGRWIDFENDYKTMDPKFMESVWWVFKQLFEK 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 176 GHLHKGAKPVHWCVDCRSALA--EAEVEYYDKTSPSIDVAFQAVDqDALKAkfavsnvngpiSLVIWTTTPWTLPANRAI 253
Cdd:PLN02882 169 GLVYKGFKVMPYSTACKTPLSnfEAGLNYKDVSDPAVMVSFPIVG-DPDNA-----------SFVAWTTTPWTLPSNLAL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 254 SIAPDFDYALVQ--IDGQAVILAKDLVESV----------MQRIGVTD-YTILGTVKGAELELLRFThP----FMGFDVP 316
Cdd:PLN02882 237 CVNPNFTYVKVRnkYTGKVYIVAESRLSALptakpkskkgSKPENAAEgYEVLAKVPGSSLVGKKYE-PlfdyFSEFSDT 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 317 A---ILGDHVTLDAGTGAVHTAPGHGPDDY-------VIGQkyGLETANPVGPDGTYLpGTYPTLDGVNVFKANDIVVAL 386
Cdd:PLN02882 316 AfrvVADDYVTDDSGTGVVHCAPAFGEDDYrvclangIIEK--GGNLPVPVDDDGCFT-EKVTDFSGRYVKDADKDIIAA 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 387 LQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQkgLRAQSLKEIKGVQWIPDW-GQARIESMVANRPDWCIS 465
Cdd:PLN02882 393 IKAKGRLVKSGSITHSYPFCWRSDTPLIYRAVPSWFVKVEE--IKDRLLENNKQTYWVPDYvKEKRFHNWLENARDWAVS 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 466 RQRTWGVPMSLFVHKDTEELhprtlELMEEVAKRVEVDGIQAWwDL-----DAKEI---LGDEADQYVKVPDTLDVWFDS 537
Cdd:PLN02882 471 RSRFWGTPLPIWISDDGEEV-----VVIGSIAELEKLSGVKVT-DLhrhfiDHITIpssRGPEFGVLRRVDDVFDCWFES 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 538 GS-----THSSVVDVRPEFAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVS 612
Cdd:PLN02882 545 GSmpyayIHYPFENKELFEKNFPADFVAEGLDQTRGWFYTLMVLSTALFDKPAFKNLICNGLVLAEDGKKMSKSLKNYPD 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 613 PQDVMNKLGADILRLWVAST----------DYTGEMAVSDEILKRAADSYR-RIRNTARFLLANLNGFDPAKDMVKPEEM 681
Cdd:PLN02882 625 PNEVIDKYGADALRLYLINSpvvraeplrfKEEGVFGVVKDVFLPWYNAYRfLVQNAKRLEVEGGAPFVPLDLAKLQNSA 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 682 VVLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSvEMGSFYLDIIKDRQYTAKADSVARRSCQTaLYHIAEALVR 761
Cdd:PLN02882 705 NVLDRWINSATQSLVKFVREEMGAYRLYTVVPYLVKFID-NLTNIYVRFNRKRLKGRTGEEDCRTALST-LYNVLLTSCK 782
|
....*...
gi 447209609 762 WMAPILSF 769
Cdd:PLN02882 783 VMAPFTPF 790
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
640-820 |
1.67e-91 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 287.50 E-value: 1.67e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 640 VSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFC 719
Cdd:cd07960 1 ISDEILKQVAEAYRKIRNTFRFLLGNLNDFDPAKDAVPYEELLELDRYALHRLNELIKEVREAYENYEFHKVYQALNNFC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 720 SVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGER-EKYVFTGEWYEGLFGL 798
Cdd:cd07960 81 TVDLSAFYLDIIKDRLYCDAKDSLERRSAQTVLYHILDALLKLLAPILPFTAEEVWEHLPGEKkEESVFLEDWPELPEEW 160
|
170 180
....*....|....*....|..
gi 447209609 799 ADSEAMndAFWDELLKVRGEVN 820
Cdd:cd07960 161 KDEELE--EKWEKLLALRDEVN 180
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
6-805 |
5.52e-91 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 314.21 E-value: 5.52e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 6 STLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLS 85
Cdd:PTZ00427 59 EMVTVTFTGVSENPNIVEEEEKVLKYWKSIDAFNTSNKLAKNKKAYIFYDGPPFATGLPHYGHLLAGIIKDCVTRYFYQC 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 86 GYDSPYVPGWDCHGLPIELKVEQEYGKPGE----KFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKT 161
Cdd:PTZ00427 139 GFSVERKFGWDCHGLPIEYEIEKENNINKKedilKMGIDVYNEKCRGIVLKYSNEWVKTVERIGRWIDFKNDYKTMDKTF 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 162 EANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALA--EAEVEYYDKTSPSIDVAFQAV--------------DQDALKAK 225
Cdd:PTZ00427 219 MESVWWVFSELYKNNYVYKSFKVMPYSCKCNTPISnfELNLNYKDTPDPSIIISFVLCsdfpkveeecnieeDKQLLGEK 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 226 FAV--------SNVNGPIS-----------LVIWTTTPWTLPANRAISIAPDFDYALV-QIDGQ-AVILAKDLVESVMQR 284
Cdd:PTZ00427 299 YSVlynnkrenSNNGNNNStnnvcyaqhseILAWTTTPWTLPSNLALCVNEHFTYLRIhHVKSNrVVIVGECRLEWIMKE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 285 I--GVTDYTILGTVKGAELELLRFTHPFMGF---------DVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGL-- 351
Cdd:PTZ00427 379 LkwNVEDLKIVNRFKGKELKGLRYKPLFTNFyekynfkerAYKILADDFVTDDAGTGIVHCAPTYGEDDFRVCKKNGVid 458
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 352 -ETA---NPVGPDGtYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQ 427
Cdd:PTZ00427 459 pEKNifiDPLDANG-YFTNEVEEVQNLYIKEADNVIKKKLKNENRLLSNNTIVHSYPFCWRSDTPLIYRAIPAWFIRVSN 537
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 428 KglRAQSLKEIKGVQWIP-DWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEelhprTLELMEEVAKRVEVDGIQ 506
Cdd:PTZ00427 538 S--TNELVKNNETTYWIPaHIKEKKFHNWIKDAKDWCISRNRYWGTPIPIWADEKME-----TVICVESIKHLEELSGVK 610
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 507 AWWDL-----DAKEILGDEADQYVK---VPDTLDVWFDSGS-----THSSVVDVRPEFAG-HAADMYLEGSDQHRGWFMS 572
Cdd:PTZ00427 611 NINDLhrhfiDHIEIKNPKGKTYPKlkrIPEVFDCWFESGSmpyakVHYPFSTEKEDFHKiFPADFIAEGLDQTRGWFYT 690
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 573 SLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTdytgeMAVSDEILKRAADSY 652
Cdd:PTZ00427 691 LLVISTLLFDKAPFKNLICNGLVLASDGKKMSKRLKNYPDPLYILDKYGADSLRLYLINS-----VAVRAENLKFQEKGV 765
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 653 RRI--------RNTARFLLANLNGFDPAKDM--VKPEEMV-----VLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMR 717
Cdd:PTZ00427 766 NEVvksfilpfYHSFRFFSQEVTRYECLNKKqfLFNTDYIykndnIMDQWIFSSVQSLTKSVHTEMKAYKLYNVLPKLLQ 845
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 718 FCSvEMGSFYLDIIKDRQYTAKADSVARRSCQTaLYHIAEALVRWMAPILSFTADEVWGYLpgerEKYVFTGEWYEG-LF 796
Cdd:PTZ00427 846 FIE-NLTNWYIRLNRDRMRGSLGEENCLQSLCT-TYRTLHLFTVLMAPFTPFITEYIYQQL----RRVKSTNEHNENnET 919
|
....*....
gi 447209609 797 GLADSEAMN 805
Cdd:PTZ00427 920 GNTKEGDLN 928
|
|
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
57-888 |
7.32e-71 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 254.92 E-value: 7.32e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 57 PPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEK----FTAAEFRAKC---REY 129
Cdd:PRK14900 56 PPNVTGSLHLGHALTATLQDVLIRWKRMSGFNTLWLPGTDHAGIATQMIVEKELKKTEKKsrhdLGREAFLERVwawKEQ 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 130 AATQVDGQRKdfiRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPS 209
Cdd:PRK14900 136 YGSRIGEQHK---ALGASLDWQRERFTMDEGLSRAVREVFVRLHEEGLIYREKKLINWCPDCRTALSDLEVEHEEAHQGE 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 210 IdvafqavdqdalkAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDfDYALVQIDGQAVIlakdlvesvmqrigvtd 289
Cdd:PRK14900 213 L-------------WSFAYPLADGSGEIVVATTRPETMLGDTAVAVHPL-DPRYMALHGKKVR----------------- 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 290 ytilgtvkgaelellrftHPFMGFDVPaILGDHVTLDA--GTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGT 367
Cdd:PRK14900 262 ------------------HPITGRTFP-IVADAILVDPkfGTGAVKVTPAHDFNDFEVGKRHGLEMITVIGPDGRMTAEA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 368 YPtLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPD- 446
Cdd:PRK14900 323 GP-LAGLDRFEARKEVKRLLAEQGLDRGAKPHVLPLGRCQRSATILEPLLSDQWYVRIEPLARPAIEAVEQGRTRFIPEq 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 447 WGQARIESMvANRPDWCISRQRTWGvpmslfvHKdteelhprtlelmeevakrvevdgIQAWWDLDAKEILGDE------ 520
Cdd:PRK14900 402 WTNTYMAWM-RNIHDWCISRQLWWG-------HQ------------------------IPAWYCPDGHVTVAREtpeacs 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 521 ---ADQYVKVPDTLDVWFDSG----STHSSVVDVrPEFAGHAADMYLE-GSDQHRGWFMSSLMISTAMKGKAPYRQVLTH 592
Cdd:PRK14900 450 tcgKAELRQDEDVLDTWFSSGlwpfSTMGWPEQT-DTLRTFYPTSVMEtGHDIIFFWVARMMMMGLHFMGEVPFRTVYLH 528
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 593 GFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEmavSDEILKRAADSYR----RIRNTARFLLANLNG 668
Cdd:PRK14900 529 PMVRDEKGQKMSKTKGNVIDPLVITEQYGADALRFTLAALTAQGR---DIKLAKERIEGYRafanKLWNASRFALMNLSG 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 669 FDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTakADSVARRSC 748
Cdd:PRK14900 606 YQERGEDPARLARTPADRWILARLQRAVNETVEALEAFRFNDAANAVYAFVWHELCDWYIELAKEALAS--EDPEARRSV 683
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 749 QTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKY-----VFTGEWYEGlfGLADSEAMND-----AFWDELLKVRGE 818
Cdd:PRK14900 684 QAVLVHCLQTSYRLLHPFMPFITEELWHVLRAQVGASawadsVLAAEYPRK--GEADEAAEAAfrpvlGIIDAVRNIRGE 761
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447209609 819 VN---KVIEQARADKKVGGSLEAAVTLYAEPELA--AKLTALGDelrfVLLTSGAtvadyndAPADAQQSEVLKG 888
Cdd:PRK14900 762 MGipwKVKLGAQAPVEIAVADPALRDLLQAGELArvHRVAGVEG----SRLVVAA-------ATAPAPQSAVGVG 825
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
25-893 |
5.83e-62 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 226.52 E-value: 5.83e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 25 EPGMLARWTDDDLYgiiRAAKKGKKTF--ILhdGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDcH-GLP 101
Cdd:PRK05729 15 EAKWYQKWEEKGYF---KPDDNSKKPFsiVI--PPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWLPGTD-HaGIA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 102 IELKVE----------QEYGKpgEKFTAA--EFRAkcrEYAATQVdGQRKdfiRLGVLGDWSHPYLTMD----------F 159
Cdd:PRK05729 89 TQMVVErqlaaegksrHDLGR--EKFLEKvwEWKE---ESGGTIT-NQLR---RLGASCDWSRERFTMDeglskavrevF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 160 KT--EANIIralgkiignghlHKGAKPVHWCVDCRSALAEAEVEYYDKtspsidvafqavdQDAL---KAKFAvsnvNGP 234
Cdd:PRK05729 160 VRlyEKGLI------------YRGKRLVNWDPKLQTALSDLEVEYKEV-------------KGKLwhiRYPLA----DGS 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 235 ISLVIWTTTPWTLPANRAISIAPDfD--YA-LVqidGQAVILakdlvesvmqrigvtdytilgtvkgaelellrfthPFM 311
Cdd:PRK05729 211 DYLVVATTRPETMLGDTAVAVNPE-DerYKhLI---GKTVIL-----------------------------------PLV 251
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 312 GFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTY--LPGTYptlDGVNVFKANDIVVALLQE 389
Cdd:PRK05729 252 GREIPIIADEYVDPEFGTGAVKITPAHDPNDFEVGKRHNLPMINIMDEDGTIneNPGEY---QGLDRFEARKAIVADLEE 328
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 390 KGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMD---QKGLRAQSLKEIKGV--QWIP---DWgqariesmVANRPD 461
Cdd:PRK05729 329 LGLLVKIEPHTHSVGHSDRSGVVIEPYLSDQWFVKMKplaKPALEAVENGEIKFVpeRWEKtyfHW--------MENIQD 400
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 462 WCISRQRTWGvpmslfvHKdteelhprtlelmeevakrvevdgIQAWWDLDAKEILGDEAD------QYVKVPDTLDVWF 535
Cdd:PRK05729 401 WCISRQLWWG-------HR------------------------IPAWYDEDGEVYVGREEPearekaLLTQDEDVLDTWF 449
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 536 DSG----ST-----HSsvvdvrPEFAghaadMYLEGSDQHRGW----F----MssLMISTAMKGKAPYRQVLTHGFTVDG 598
Cdd:PRK05729 450 SSAlwpfSTlgwpeKT------EDLK-----RFYPTSVLVTGFdiifFwvarM--IMMGLHFTGQVPFKDVYIHGLVRDE 516
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 599 QGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGE-MAVSDEILkraaDSYR----RIRNTARFLLANLNGFDPAK 673
Cdd:PRK05729 517 QGRKMSKSKGNVIDPLDLIDKYGADALRFTLAALASPGRdIRFDEERV----EGYRnfanKLWNASRFVLMNLEGADVGE 592
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 674 DmVKPEEMVVLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRF-----CsvemgSFYLDIIKDRQYTAkadsvARRSC 748
Cdd:PRK05729 593 L-PDPEELSLADRWILSRLNRTVAEVTEALDKYRFDEAARALYEFiwnefC-----DWYLELAKPVLQEA-----AKRAT 661
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 749 QTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTgewyeglfgLADSEAMNDAFWDELLKvrgEVNKVIE---- 824
Cdd:PRK05729 662 RATLAYVLEQILRLLHPFMPFITEELWQKLAPLGIEESIM---------LAPWPEADEAIDEAAEA---EFEWLKElita 729
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 447209609 825 --QARADKKVGGSLEAAVTLYAEPELAAKLTALGDEL--RFVLLTSGATVADYNDAPADAQQSeVLKGLKVAL 893
Cdd:PRK05729 730 irNIRAEMNIPPSKKLPLLLKGADAEDRARLEANEAYikRLARLESLEILADDEEAPEGAASA-VVGGAELFL 801
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
44-788 |
6.14e-61 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 224.43 E-value: 6.14e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 44 AKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEK---FTAA 120
Cdd:PLN02943 83 FDRGGDPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIPGTDHAGIATQLVVEKMLASEGIKrtdLGRD 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 121 EFRAKCRE----YAATqVDGQRKdfiRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALA 196
Cdd:PLN02943 163 EFTKRVWEwkekYGGT-ITNQIK---RLGASCDWSRERFTLDEQLSRAVVEAFVRLHEKGLIYQGSYMVNWSPNLQTAVS 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 197 EAEVEYYDKtsPSIDVAFqavdqdalkaKFAVSNvnGPIS-LVIWTTTPWTLPANRAISIAPDFD-YAlvqidgqavila 274
Cdd:PLN02943 239 DLEVEYSEE--PGTLYYI----------KYRVAG--GSEDfLTIATTRPETLFGDVAIAVNPEDDrYS------------ 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 275 kdlvesvmQRIGvtdytilgtvkgaELELLRFTHpfmGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETA 354
Cdd:PLN02943 293 --------KYIG-------------KMAIVPMTY---GRHVPIIADRYVDKDFGTGVLKISPGHDHNDYLLARKLGLPIL 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 355 NPVGPDGTYlpgtyPTLDGVNVFKANDIVVALLQEKGalLHVEKMQHSY--PCCWRHKTPIIFRATPQWFVSMD---QKG 429
Cdd:PLN02943 349 NVMNKDGTL-----NEVAGLYWFEAREKLWSDLEETG--LAVKKEPHTLrvPRSQRGGEVIEPLVSKQWFVTMEplaEKA 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 430 LRAQSLKEIKgvqWIPDWGQARIESMVANRPDWCISRQRTWG--VPMSLFVHKDTEElhprtlelmEEVAKRVEVDGIQA 507
Cdd:PLN02943 422 LKAVENGELT---IIPERFEKIYNHWLSNIKDWCISRQLWWGhrIPVWYIVGKDCEE---------DYIVARSAEEALEK 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 508 wwdldAKEILGDEADQYvKVPDTLDVWFDSGSTHSSVV---DVRPE-FAGHAADMYLE-GSDQHRGWFMSSLMISTAMKG 582
Cdd:PLN02943 490 -----AREKYGKDVEIY-QDPDVLDTWFSSALWPFSTLgwpDVSAEdFKKFYPTTVLEtGHDILFFWVARMVMMGIEFTG 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 583 KAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFL 662
Cdd:PLN02943 564 TVPFSYVYLHGLIRDSQGRKMSKTLGNVIDPLDTIKEFGTDALRFTLALGTAGQDLNLSTERLTSNKAFTNKLWNAGKFV 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 663 LANL--------------NGFDPAKDMVKpeeMVVLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSVEMGSFYL 728
Cdd:PLN02943 644 LQNLpsqsdtsawehilaCKFDKEESLLS---LPLPECWVVSKLHELIDSVTTSYDKYFFGDVGREIYDFFWSDFADWYI 720
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 729 DIIKDRQYTAKADSVARRScQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFT 788
Cdd:PLN02943 721 EASKTRLYHSGDNSALSRA-QAVLLYVFENILKLLHPFMPFVTEELWQALPYRKEALIVS 779
|
|
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
57-893 |
1.06e-60 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 223.00 E-value: 1.06e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 57 PPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDcH-GLPIELKVE----------QEYGKpgEKFT--AAEFR 123
Cdd:COG0525 43 PPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWQPGTD-HaGIATQAVVErqlaeegksrHDLGR--EKFLerVWEWK 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 124 AkcrEYAATQVDGQRkdfiRLGVLGDWSHPYLTMD----------FKT--EANIIralgkiignghlHKGAKPVHWCVDC 191
Cdd:COG0525 120 E---ESGGTITNQLR----RLGASCDWSRERFTMDeglskavrevFVRlyEKGLI------------YRGKRLVNWDPKL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 192 RSALAEAEVEYydktspsidvafqaVDQDA----LKAKFAvsnvNGPISLVIWTTTPWTLPANRAISIAPDfD--YA-LV 264
Cdd:COG0525 181 KTALSDLEVEH--------------EEVKGhlwhIRYPLA----DGSGYIVVATTRPETMLGDTAVAVHPE-DerYKhLI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 265 qidGQAVILakdlvesvmqrigvtdytilgtvkgaelellrfthPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYV 344
Cdd:COG0525 242 ---GKTVIL-----------------------------------PLVGREIPIIADEYVDPEFGTGAVKITPAHDPNDFE 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 345 IGQKYGLETANPVGPDGTyLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVS 424
Cdd:COG0525 284 VGKRHNLPMINILDEDGT-INENAGKYRGLDRFEARKAIVADLEELGLLVKVEPHKHSVGHSDRSGTVIEPYLSDQWFVK 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 425 MD---QKGLRAQSLKEIKGV--QWIP---DWgqariesMVaNRPDWCISRQRTWGvpmslfvHKdteelhprtlelmeev 496
Cdd:COG0525 363 MKplaKPAIEAVEDGEIKFVpeRWEKtyfHW-------ME-NIRDWCISRQLWWG-------HR---------------- 411
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 497 akrvevdgIQAWWDLDAKEILG-DEADQYVKV--------PDTLDVWFDSG----SThssvvdvrpefaghaadMylegs 563
Cdd:COG0525 412 --------IPAWYCPDGEVYVArTEPEACAKAgsvnltqdEDVLDTWFSSAlwpfST-----------------L----- 461
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 564 dqhrGW------------------------F----MssLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQD 615
Cdd:COG0525 462 ----GWpektedlkyfyptsvlvtgfdiifFwvarM--IMMGLHFTGEVPFKDVYIHGLVRDEQGRKMSKSKGNVIDPLD 535
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 616 VMNKLGADILRLWVAStdytgeMAVS------DEilKRaADSYRR----IRNTARFLLANLNGFDPAKDmVKPEEMVVLD 685
Cdd:COG0525 536 LIDKYGADALRFTLAA------LASPgrdikfDE--ER-VEGYRNfankLWNASRFVLMNLEGFDPGLD-PDPEELSLAD 605
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 686 RWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRF-----CsvemgSFYLDIIKDRQYtaKADSVARRSCQTALYHIAEALV 760
Cdd:COG0525 606 RWILSRLNKTIAEVTEALEKYRFDEAAQALYDFvwnefC-----DWYLELAKPRLY--GGDEAAKRETRATLVYVLEQIL 678
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 761 RWMAPILSFTADEVWGYLP-GEREKYVFTGEWYEGLFGLADSEAMNDAfwdELLKvrgEVNKVIEQARADKKVGGSLEAA 839
Cdd:COG0525 679 RLLHPFMPFITEEIWQKLPpRKEGESIMLAPWPEADEELIDEEAEAEF---EWLK---EVISAIRNIRAEMNIPPSKKLP 752
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*
gi 447209609 840 VTLYAE-PELAAKLTALGDELRFVLLTSGATVADyNDAPADAQQSeVLKGLKVAL 893
Cdd:COG0525 753 LLLKGAdEADRARLEENAAYIKRLARLEEITILV-DEKPEGAASA-VVGGAEVFL 805
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
32-784 |
4.47e-59 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 219.49 E-value: 4.47e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 32 WTDDDLYGIIRAA--KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVE-- 107
Cdd:PTZ00419 41 WEKSGFFKPAEDAksLNSGKKFVIVLPPPNVTGYLHIGHALTGAIQDSLIRYHRMKGDETLWVPGTDHAGIATQVVVEkk 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 108 ---------QEYGKpgEKFTAAEFRAKcREYAAtQVDGQRKdfiRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHL 178
Cdd:PTZ00419 121 lmkeenktrHDLGR--EEFLKKVWEWK-DKHGN-NICNQLR---RLGSSLDWSREVFTMDEQRSKAVKEAFVRLYEDGLI 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 179 HKGAKPVHWCVDCRSALAEAEVEYYDKTSPS---IDVAFQAVDQDALkAKFAVSNVN-GPISLVIWTTTPWTLPANRAIS 254
Cdd:PTZ00419 194 YRDTRLVNWCCYLKTAISDIEVEFEEIEKPTkitIPGYDKKVEVGVL-WHFAYPLEDsGQEEIVVATTRIETMLGDVAVA 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 255 IAP-DFDYalvqidgqavilaKDLVesvmqrigvtdytilgtvkGAELellrfTHPFM-GFDVPAILGD-HVTLDAGTGA 331
Cdd:PTZ00419 273 VHPkDERY-------------KKLH-------------------GKEL-----IHPFIpDRKIPIIADDeLVDMEFGTGA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 332 VHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPtLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKT 411
Cdd:PTZ00419 316 VKITPAHDPNDYEIAKRHNLPFINIFTLDGKINENGGE-FAGMHRFDCRRKIEEELKEMGLLRDKVPNPMRLPRCSRSGD 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 412 PIIFRATPQWFVS---MDQKGLRAQSLKEIKgvqWIPdwgqariESMVA-------NRPDWCISRQRTWG--VPMSLFVH 479
Cdd:PTZ00419 395 IVEPMLIPQWYVNckdMAKRAVEAVRNGELK---IIP-------SSHENvwyhwleNIQDWCISRQLWWGhrIPAYRVIS 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 480 KDteelhPRTLELMEE--VAKRVEVDGIQawwdlDAKEILGDEADQY--VKVPDTLDVWFDSGSTHSSVV---DVRPEFA 552
Cdd:PTZ00419 465 KG-----PETDPSDEEpwVVARSEEEALE-----KAKKKFGLSEEDFelEQDEDVLDTWFSSGLFPFSTLgwpDQTDDLQ 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 553 GHAADMYLE-GSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMN---------KL-- 620
Cdd:PTZ00419 535 RFFPTSLLEtGSDILFFWVARMVMMSLHLTDKLPFKTVFLHAMVRDSQGEKMSKSKGNVIDPLEVIEgislqdlnqKLye 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 621 --------------------------GADILRLWVAStdYTGE-MAVSDEIlKRAAdSYR----RIRNTARFLLANLNGF 669
Cdd:PTZ00419 615 gnlpekeikraielqkkefpngipecGTDALRFGLLA--YTQQgRNINLDI-NRVV-GYRhfcnKLWNAVKFALMKLLKD 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 670 DPA--KDMVKPEEMVVL---DRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRqYTAKADSVA 744
Cdd:PTZ00419 691 FNLpnSTLFKPNNVESLpweDKWILHRLNVAIKEVTEGFKEYDFSEATQATYNFWLYELCDVYLELIKPR-LSKQSDGER 769
|
810 820 830 840
....*....|....*....|....*....|....*....|
gi 447209609 745 RRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREK 784
Cdd:PTZ00419 770 KQHAQDVLHTVLDIGLRLLHPMMPFITEELYQRLPNYLRK 809
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
30-898 |
1.64e-57 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 215.15 E-value: 1.64e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 30 ARWTDDDLYGIirAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQ- 108
Cdd:PLN02381 111 AWWEKSGYFGA--DAKSSKPPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRMSGYNALWVPGVDHAGIATQVVVEKk 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 109 ----------EYGKpgEKFTAAEFRAKcREYAATQVDGQRkdfiRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHL 178
Cdd:PLN02381 189 lmrerhltrhDIGR--EEFVSEVWKWK-DEYGGTILNQLR----RLGASLDWSRECFTMDEQRSKAVTEAFVRLYKEGLI 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 179 HKGAKPVHWcvDC--RSALAEAEVEYYD-KTSPSIDV-AFQAVDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAIS 254
Cdd:PLN02381 262 YRDIRLVNW--DCtlRTAISDVEVDYIDiKERTLLKVpGYDKPVEFGVLTSFAYPLEGGLGEIVVATTRIETMLGDTAIA 339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 255 IAPDfDYALVQIDGQAVIlakdlvesvmqrigvtdytilgtvkgaelellrftHPFMGFDVPaILGDHVTLDA--GTGAV 332
Cdd:PLN02381 340 IHPD-DERYKHLHGKFAV-----------------------------------HPFNGRKLP-IICDAILVDPnfGTGAV 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 333 HTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTP 412
Cdd:PLN02381 383 KITPAHDPNDFEVGKRHNLEFINIFTDDGKINSNGGSEFAGMPRFAAREAVIEALQKKGLYRGAKNNEMRLGLCSRTNDV 462
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 413 IIFRATPQWFV---SMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWG--VPmSLFVHKDTEELHP 487
Cdd:PLN02381 463 VEPMIKPQWFVncsSMAKQALDAAIDGENKKLEFIPKQYLAEWKRWLENIRDWCISRQLWWGhrIP-AWYVTLEDDQLKE 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 488 RTLELMEEVAKRVEVDGIqawwdLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVV---DVRPEFAGHAADMYLE-GS 563
Cdd:PLN02381 542 LGSYNDHWVVARNESDAL-----LEASQKFPGKKFELSQDPDVLDTWFSSGLFPLSVLgwpDDTDDLKAFYPTSVLEtGH 616
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 564 DQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKL----------------------- 620
Cdd:PLN02381 617 DILFFWVARMVMMGMQLGGDVPFRKVYLHPMIRDAHGRKMSKSLGNVIDPLEVINGIsleglhkrleegnldpkelvvak 696
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 621 --------------GADILRLWVAStdYTgemAVSDEI---LKRAAdSYR----RIRNTARFLLANL-NGFDPAKDmVKP 678
Cdd:PLN02381 697 egqkkdfpngiaecGTDALRFALVS--YT---AQSDKInldILRVV-GYRqwcnKLWNAVRFAMSKLgDDYTPPAT-LSV 769
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 679 EEMVVLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKdrQYTAKAD---SVARRSCQTALYHI 755
Cdd:PLN02381 770 ETMPFSCKWILSVLNKAISKTVSSLDAYEFSDAASTVYSWWQYQFCDVFIEAIK--PYFAGDNpefASERAAAQDTLWIC 847
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 756 AEALVRWMAPILSFTADEVWGYLPG----EREKYVFTGEWYEGLFGLADSEAMN--DAFWDELLKVRGEVNKVIEQARAD 829
Cdd:PLN02381 848 LDTGLRLLHPFMPFVTEELWQRLPQpkdhTRKDSIMISEYPSAVEAWTNEKVEYemDLVLSTVKCLRSLRAEVLEKQKNE 927
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447209609 830 KKvggsleAAVTLYAEPELAAKLTALGDELRFVL-LTSGATVADYNDA-PADAQQSEVLKGLKVALsKAEG 898
Cdd:PLN02381 928 RL------PAFALCRNQEIAAIIKSHQLEILTLAnLSSLKVLLSENDApPAGCAFENVNENLKVYL-QAQG 991
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
57-631 |
1.88e-42 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 159.72 E-value: 1.88e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 57 PPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPG---EKFTAAEFRAKCREYAATQ 133
Cdd:cd00817 9 PPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQVVVEKKLGIEGktrHDLGREEFLEKCWEWKEES 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 134 VDGQRKDFIRLGVLGDWSHPYLTMDFKTeaniiralgkiignghlhkgakpvhwcvdcRSALAEAEVEYYDKtspsiDVA 213
Cdd:cd00817 89 GGKIREQLKRLGASVDWSREYFTMDPGL------------------------------SRAVQEAFVRLYEK-----GLI 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 214 FQAvdqdalkakfavsnvngpISLVIWTTTpwtlpANRAISiapdfdyalvqidgqavilakdlvesvmqrigvtdytil 293
Cdd:cd00817 134 YRD------------------NRLVNWCPK-----LRTAIS--------------------------------------- 151
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 294 gtvkgaelellrfthpfmgfdvpailgdhvtldagtgavhtapghgpddyvigqkygletanpvgpdgtylpgtyptldg 373
Cdd:cd00817 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 374 vnvfkanDIVVallqekgallhvekmqhsypcCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIE 453
Cdd:cd00817 152 -------DIEV---------------------CSRSGDVIEPLLKPQWFVKVKDLAKKALEAVKEGDIKFVPERMEKRYE 203
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 454 SMVANRPDWCISRQRTWGVPMSLFVHKDTEElhprtlelmeEVAKRVEVDGIQAwwDLDAKEILGDEADqYVKVPDTLDV 533
Cdd:cd00817 204 NWLENIRDWCISRQLWWGHRIPAWYCKDGGH----------WVVAREEDEAIDK--AAPEACVPCGGEE-LKQDEDVLDT 270
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 534 WFDSGSTHSSV---VDVRPEF-AGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGN 609
Cdd:cd00817 271 WFSSSLWPFSTlgwPEETKDLkKFYPTSLLVTGHDIIFFWVARMIMRGLKLTGKLPFKEVYLHGLVRDEDGRKMSKSLGN 350
|
570 580
....*....|....*....|..
gi 447209609 610 TVSPQDVMNKLGADILRLWVAS 631
Cdd:cd00817 351 VIDPLDVIDGYGADALRFTLAS 372
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
50-193 |
6.80e-40 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 150.26 E-value: 6.80e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 50 TFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREY 129
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAERKGGRKKKTIWIEEFREDPKEF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447209609 130 AATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPV----HWCVDCRS 193
Cdd:cd00668 81 VEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYRGTHPVriteQWFFDMPK 148
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
410-633 |
2.38e-39 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 148.72 E-value: 2.38e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 410 KTPIIFRATPQWFVSMDQkgLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSlfvhkdteelhprt 489
Cdd:cd00668 131 RGTHPVRITEQWFFDMPK--FKEKLLKALRRGKIVPEHVKNRMEAWLESLLDWAISRQRYWGTPLP-------------- 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 490 lelmeevakrvevdgiqawwdldakeilgdeadqyvkvPDTLDVWFDSGSTHSSVVDVRPEFAG----HAADMYLEGSDQ 565
Cdd:cd00668 195 --------------------------------------EDVFDVWFDSGIGPLGSLGYPEEKEWfkdsYPADWHLIGKDI 236
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447209609 566 HRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTD 633
Cdd:cd00668 237 LRGWANFWITMLVALFGEIPPKNLLVHGFVLDEGGQKMSKSKGNVIDPSDVVEKYGADALRYYLTSLA 304
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
685-842 |
2.19e-32 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 122.51 E-value: 2.19e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 685 DRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVArrscQTALYHIAEALVRWMA 764
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLSDWYLELIKDRLYGEEPDSRA----QTTLYEVLETLLRLLA 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447209609 765 PILSFTADEVWgylpgeREKYVFTGEWYEglfgladSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTL 842
Cdd:pfam08264 77 PFMPFITEELW------QKESIHLAPWPE-------DAELEEAELEEAFELRQEIVQAIRKLRSELKIKKSLPLEVVI 141
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
64-847 |
6.37e-24 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 108.42 E-value: 6.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 64 IHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI----ELKVEQE----------YGKPGE---KFTAAEFRAKC 126
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLFPMAFHVTGTPIlgiaERIARGDpetielykslYGIPEEeleKFKDPEYIVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 127 --REYaatqvdgqRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSAL--------A 196
Cdd:PRK12300 81 fsEEA--------KEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPVgdhdlldgE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 197 EAEVEYYDktspsidvafqAVdqdalkaKFAVSNVngpISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD 276
Cdd:PRK12300 153 EPEIVEYT-----------LI-------KFEESED---LILPAATLRPETIFGVTNLWVNPDATYVKAEVDGEKWIVSKE 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 277 LVESV-MQRIGVTdytILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYV-----IGQKYG 350
Cdd:PRK12300 212 AAEKLsFQDRDVE---IIEEIKGSELIGKKVKNPVTGKEVPILPADFVDPDNGTGVVMSVPAHAPYDYValrdlKKNKEL 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 351 LETANPV--------------------GP---------DGT-----------YLPGTYPTLDGVNVFKANDIVVALLQEK 390
Cdd:PRK12300 289 LDVIEPIplievegygefpakevveklGIksqedpeleEATkevyraefhkgVLKENTGEYAGKPVREAREKITKDLIEK 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 391 G-ALLHVEKMQHSYPCcwRHKTPIIFRATP-QWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQR 468
Cdd:PRK12300 369 GiADIMYEFSNRPVYC--RCGTECVVKVVKdQWFIDYSDPEWKELAHKALDNMEIIPEEYRKEFENTIDWLKDRACARRR 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 469 TWGVPM---------SL-----------FVHK------DTEELHPRTLELM-------EEVAKRVEVDgiqawwdldaKE 515
Cdd:PRK12300 447 GLGTRLpwdeewiieSLsdstiymayytIAHKireygiKPEQLTPEFFDYVflgkgdpEEVSKKTGIP----------KE 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 516 ILgdeadqyvkvpdtldvwfdsgsthssvVDVRPEFA-GHAADMYLEGSD---QHRGWFMsslMISTAM--KGKAPyRQV 589
Cdd:PRK12300 517 IL---------------------------EEMREEFLyWYPVDWRHSGKDlipNHLTFFI---FNHVAIfpEEKWP-RGI 565
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 590 LTHGF-TVDGQgrKMSKSIGNTVSPQDVMNKLGADILRLWVAST-DYTGEMAVSDEILKRAADSYRRIRNTARFLlanln 667
Cdd:PRK12300 566 VVNGFvLLEGK--KMSKSKGNVIPLRKAIEEYGADVVRLYLTSSaELLQDADWREKEVESVRRQLERFYELAKEL----- 638
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 668 gfdpaKDMVKPEEMVVLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLmrfcsvemgsFYlDIIKD-RQYTAKADSVARR 746
Cdd:PRK12300 639 -----IEIGGEEELRFIDKWLLSRLNRIIKETTEAMESFQTRDAVQEA----------FY-ELLNDlRWYLRRVGEANNK 702
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 747 scqtALYHIAEALVRWMAPILSFTADEVWGYLPGerEKYVFTGEWYEglfglADSEAMNdafwDELLKVRGEVNKVIEQA 826
Cdd:PRK12300 703 ----VLREVLEIWIRLLAPFTPHLAEELWHKLGG--EGFVSLEKWPE-----PDESKID----EEAELAEEYVKRLIEDI 767
|
890 900
....*....|....*....|.
gi 447209609 827 RADKKVGGSLEAAVTLYAEPE 847
Cdd:PRK12300 768 REILKVAKIKPKKVYIYVAPD 788
|
|
| Anticodon_Ia_like |
cd07375 |
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This ... |
642-767 |
1.03e-14 |
|
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This domain is found in a variety of class Ia aminoacyl tRNA synthetases, C-terminal to the catalytic core domain. It recognizes and specifically binds to the anticodon of the tRNA. Aminoacyl tRNA synthetases catalyze the transfer of cognate amino acids to the 3'-end of their tRNAs by specifically recognizing cognate from non-cognate amino acids. Members include valyl-, leucyl-, isoleucyl-, cysteinyl-, arginyl-, and methionyl-tRNA synthethases. This superfamily also includes a domain from MshC, an enzyme in the mycothiol biosynthetic pathway.
Pssm-ID: 153408 [Multi-domain] Cd Length: 117 Bit Score: 71.38 E-value: 1.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 642 DEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMvvlDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCSV 721
Cdd:cd07375 1 EERLKQARAFLNRLYRLLSFFRKALGGTQPKWDNELLEEA---DRELLARLQEFIKRTTNALEALDPTTAVQELFKFTNE 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 447209609 722 EmgSFYLDIIKDRQYTAKadsvARRSCQTALYHIAEALVRWMAPIL 767
Cdd:cd07375 78 L--NWYLDELKPALQTEE----LREAVLAVLRAALVVLTKLLAPFT 117
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
651-775 |
3.16e-14 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 70.28 E-value: 3.16e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 651 SYRR----IRNTARFLLANLNGFDPAKDMVKPEEmvVLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRF-----CSV 721
Cdd:cd07962 8 GGRNfcnkLWNAARFVLMNLEDDDEPEEDPESLS--LADRWILSRLNKTVEEVTEALENYRFSEAATALYEFfwndfCDW 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 447209609 722 emgsfYLDIIKDRQYtaKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVW 775
Cdd:cd07962 86 -----YLELVKPRLY--GEDEEEKKAARATLYYVLETILRLLHPFMPFITEELW 132
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
585-778 |
3.36e-14 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 76.31 E-value: 3.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 585 PYRQVLTHGF-TVDGQgrKMSKSIGNTVSPQDVMNKLGADILRLWVAS-------TDYTGEmavsdEILKR-----AAD- 650
Cdd:COG0143 311 LPKKVFAHGFlTVEGE--KMSKSRGNVIDPDDLLDRYGPDALRYYLLRevpfgqdGDFSWE-----DFVARvnsdlANDl 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 651 ---SYRrirnTARFLLANLNGFDPAKDMVKPEEMVVLDRwavgcAKAAQEDILNAYEAYDFHEVVQRLMRFcsVEMGSFY 727
Cdd:COG0143 384 gnlASR----TLSMIHKYFDGKVPEPGELTEADEELLAE-----AEAALEEVAEAMEAFEFRKALEEIMAL--ARAANKY 452
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 728 LD------IIKDRQytakadsvaRRSCQTALYHIAEA---LVRWMAPILSFTADEVWGYL 778
Cdd:COG0143 453 IDetapwkLAKDED---------PERLATVLYTLLEAlriLAILLKPFLPETAEKILEQL 503
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
657-775 |
8.69e-14 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 70.66 E-value: 8.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 657 NTARFLL--ANLNGFDPAKDMVKPEEMVVLDRWAVgcAKAAQ--EDILNAYEAYDFHEVVQRLMRFCsVEMGSFYLDIIK 732
Cdd:cd07961 19 NAYRFFVtyANLDGFDPGKDDDAVASLNVLDRWIL--SRLNSliKEVTEEMEAYDLYTAVRALLEFI-DELTNWYIRRNR 95
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 447209609 733 DRQYTAKADSVARRSCQTaLYHIAEALVRWMAPILSFTADEVW 775
Cdd:cd07961 96 KRFWGEEGDDDKLAAYAT-LYEVLLTLSRLMAPFTPFITEEIY 137
|
|
| metG |
TIGR00398 |
methionine--tRNA ligase; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ... |
58-201 |
5.44e-13 |
|
methionine--tRNA ligase; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ligase. This model appears to recognize the methionyl-tRNA synthetase of every species, including eukaryotic cytosolic and mitochondrial forms. The UPGMA difference tree calculated after search and alignment according to this model shows an unusual deep split between two families of MetG. One family contains forms from the Archaea, yeast cytosol, spirochetes, and E. coli, among others. The other family includes forms from yeast mitochondrion, Synechocystis sp., Bacillus subtilis, the Mycoplasmas, Aquifex aeolicus, and Helicobacter pylori. The E. coli enzyme is homodimeric, although monomeric forms can be prepared that are fully active. Activity of this enzyme in bacteria includes aminoacylation of fMet-tRNA with Met; subsequent formylation of the Met to fMet is catalyzed by a separate enzyme. Note that the protein from Aquifex aeolicus is split into an alpha (large) and beta (small) subunit; this model does not include the C-terminal region corresponding to the beta chain. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273058 [Multi-domain] Cd Length: 530 Bit Score: 72.41 E-value: 5.44e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 58 PYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPgekftaaefrakcREYAATQVDGQ 137
Cdd:TIGR00398 8 PYANGKPHLGHAYTTILADVYARYKRLRGYEVLFVCGTDEHGTKIELKAEQEGLTP-------------KELVDKYHEEF 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 447209609 138 RKDFIRLGVLGDWSHPylTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVE 201
Cdd:TIGR00398 75 KDDWKWLNISFDRFIR--TTDEEHKEIVQKIFQKLKENGYIYEKEIKQLYCPECEMFLPDRYVE 136
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
58-201 |
9.19e-13 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 71.17 E-value: 9.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 58 PYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEyGKPGEkftaaefrakcrEYAATQVDGQ 137
Cdd:pfam09334 8 PYANGPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAEKE-GITPE------------ELVDRYHEIH 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 447209609 138 RKDFIRLGVLGDW-------SHPYLTMDFkteaniiraLGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVE 201
Cdd:pfam09334 75 REDFKKFNISFDDygrttseRHHELVQEF---------FLKLYENGYIYEKEIEQFYCPSDERFLPDRYVE 136
|
|
| CysS |
COG0215 |
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA ... |
592-678 |
3.43e-12 |
|
Cysteinyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Cysteinyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439985 [Multi-domain] Cd Length: 465 Bit Score: 69.75 E-value: 3.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 592 HGF-TVDGQgrKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFD 670
Cdd:COG0215 256 NGFlTVNGE--KMSKSLGNFFTVRDLLKKYDPEVLRFFLLSAHYRSPLDFSEEALEEAEKALERLYNALRRLEEALGAAD 333
|
....*...
gi 447209609 671 PAKDMVKP 678
Cdd:COG0215 334 SSAEEIEE 341
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
58-143 |
1.51e-11 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 66.79 E-value: 1.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 58 PYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEyGKPGEKFtaaefrakCREYAATQVDGQ 137
Cdd:cd00814 9 PYVNGVPHLGHLYGTVLADVFARYQRLRGYDVLFVTGTDEHGTKIEQKAEEE-GVTPQEL--------CDKYHEIFKDLF 79
|
90
....*....|..
gi 447209609 138 RK------DFIR 143
Cdd:cd00814 80 KWlnisfdYFIR 91
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
13-487 |
6.53e-10 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 63.30 E-value: 6.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 13 TGFPmrgdLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGS-IHIGHSVNKILKDIIVKSKGLSGYDSPY 91
Cdd:PLN02563 78 RAYP----FHEIEPKWQRYWEENRTFRTPDDVDTSKPKFYVLDMFPYPSGAgLHVGHPEGYTATDILARYKRMQGYNVLH 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 92 VPGWDCHGLPIElkveqEYgkpgekftAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMD---FKTEANIIRA 168
Cdd:PLN02563 154 PMGWDAFGLPAE-----QY--------AIETGTHPKITTLKNIARFRSQLKSLGFSYDWDREISTTEpeyYKWTQWIFLQ 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 169 LGKiigNGHLHKGAKPVHWCVDCRSALAEAEV-------------------------EYYDKTSPSID------------ 211
Cdd:PLN02563 221 LLK---RGLAYQAEVPVNWCPALGTVLANEEVvdglsergghpvirkpmrqwmlkitAYADRLLEDLDdldwpesikemq 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 212 -----------VAFQAVDQDALKAKfavsnvngpISLVIWTTTPWTLPANRAISIAPDfdyalvqidgqavilaKDLVES 280
Cdd:PLN02563 298 rnwigrsegaeLDFSVLDGEGKERD---------EKITVYTTRPDTLFGATYLVVAPE----------------HPLLSS 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 281 VM---QRIGVTDYTILGTVKgAELELLR--------FT-----HPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYV 344
Cdd:PLN02563 353 LTtaeQKEAVEEYVDAASRK-SDLERTElqkektgvFTgsyaiNPATGEAIPIWVADYVLGSYGTGAIMAVPAHDTRDFE 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 345 IGQKYGLETANPVGP-DGTYLPGTYP-TLDGVNVFKANDivvallqekgallhvekmqhsypccwrhktpiifratpqwf 422
Cdd:PLN02563 432 FAQKFDLPIKWVVKPaDGNEDDAEKAyTGEGVIVNSSSS----------------------------------------- 470
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447209609 423 vSMDQKGLRAQSLKEiKGVQWIPDWGQARIESMVANRpDWCISRQRTWGVPMSLFVHKDTEELHP 487
Cdd:PLN02563 471 -GLDINGLSSKEAAK-KVIEWLEETGNGKKKVNYKLR-DWLFARQRYWGEPIPVVFLEDSGEPVP 532
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
58-109 |
1.42e-09 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 61.71 E-value: 1.42e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 447209609 58 PYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQE 109
Cdd:PRK00133 11 PYANGPIHLGHLVEYIQADIWVRYQRMRGHEVLFVCADDAHGTPIMLKAEKE 62
|
|
| zf-FPG_IleRS |
pfam06827 |
Zinc finger found in FPG and IleRS; This zinc binding domain is found at the C-terminus of ... |
898-925 |
1.51e-09 |
|
Zinc finger found in FPG and IleRS; This zinc binding domain is found at the C-terminus of isoleucyl tRNA synthetase and the enzyme Formamidopyrimidine-DNA glycosylase EC:3.2.2.23.
Pssm-ID: 429140 [Multi-domain] Cd Length: 28 Bit Score: 53.75 E-value: 1.51e-09
10 20
....*....|....*....|....*...
gi 447209609 898 GEKCPRCWHYTRDVGKVAEHAEICGRCV 925
Cdd:pfam06827 1 GEKCPRCWTYIEKVGVGGRSTYFCPRCQ 28
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
587-778 |
1.69e-09 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 61.44 E-value: 1.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 587 RQVLTHGF-TVDGQgrKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGemavSDEILKRAADSYRR-------IRN- 657
Cdd:PRK11893 285 KRVFAHGFlTLDGE--KMSKSLGNVIDPFDLVDEYGVDAVRYFLLREIPFG----QDGDFSREAFINRInadlandLGNl 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 658 ---TARFLLANLNGFDPAKDMVKPEEMVVLDRwavgcAKAAQEDILNAYEAYDFHEVVQRLMRFcsVEMGSFYLDIIKdr 734
Cdd:PRK11893 359 aqrTLSMIAKNFDGKVPEPGALTEADEALLEA-----AAALLERVRAAMDNLAFDKALEAILAL--VRAANKYIDEQA-- 429
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 447209609 735 QYTAKADSVARRScqTALYHIAEAlVRWMA----PILSFTADEVWGYL 778
Cdd:PRK11893 430 PWSLAKTDPERLA--TVLYTLLEV-LRGIAvllqPVMPELAAKILDQL 474
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
307-837 |
3.44e-09 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 60.83 E-value: 3.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 307 THPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLE----TANPVGPDGTYLPGTYPT---------LDG 373
Cdd:COG0495 312 INPLTGEKIPIWIADYVLMDYGTGAVMAVPAHDQRDFEFAKKYGLPikqvIAPEDGDDPDILEEAYTGdgvlinsgeFDG 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 374 VNVFKANDIVVALLQEKGallhvekmqhsypccWRHKTpIIFRatpqwfvsmdqkgLRaqslkeikgvqwipdwgqarie 453
Cdd:COG0495 392 LDSEEAKEAIIEWLEEKG---------------LGKRK-VNYR-------------LR---------------------- 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 454 smvanrpDWCISRQRTWG--VPMslfVHKDT--------EELhPrtLELMEEVakrvevdgiqawwDLDAKeilG----D 519
Cdd:COG0495 421 -------DWLISRQRYWGepIPI---IHCEDcgvvpvpeDQL-P--VELPEDV-------------DFDPT---GgsplA 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 520 EADQYVKVP------------DTLDVWFDSG-------STHSSVVDVRPEFAGH--AADMYLEGSDqH--------RGW- 569
Cdd:COG0495 472 RAPEWVNVTcpkcggparretDTMDTFVDSSwyylrytDPHNDEAPFDPEAANYwlPVDQYIGGIE-HailhllyaRFFt 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 570 -FMSSL-MISTamkgKAPYRQVLTHG--------FTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVAStdyTG--E 637
Cdd:COG0495 551 kVLRDLgLVSF----DEPFKRLLTQGmvlevgkdGVVIGGIEKMSKSKGNVVDPDEIIEKYGADTLRLFEMF---AGppE 623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 638 MAV--SDE-------ILKRAadsYRRIRNTARFLLANLNGFD-PAKDMVKpeemvVLDRwavgCAKAAQEDIlnayEAYD 707
Cdd:COG0495 624 RDLewSDSgvegayrFLNRV---WRLVVDEAEALKLDVADLSeADKELRR-----ALHK----TIKKVTEDI----ERLR 687
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 708 FHEVVQRLMRFCSvEMgsfyldiikdrqYTAKADSVARRScqtALYHIAEALVRWMAPILSFTADEVWGYLpGErEKYVF 787
Cdd:COG0495 688 FNTAIAALMELVN-AL------------YKAKDSGEADRA---VLREALETLVLLLAPFAPHIAEELWERL-GH-EGSVA 749
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447209609 788 TGEWYEglfglADSEAMNDafwDELL-------KVRGEVN--------KVIEQARADKKVGGSLE 837
Cdd:COG0495 750 DAPWPE-----ADEAALVE---DEVTivvqvngKVRGKIEvpadaskeELEAAALADEKVQKFLE 806
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
587-778 |
5.32e-08 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 56.70 E-value: 5.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 587 RQVLTHGF-TVDGqgRKMSKSIGNTVSPQDVMNKLGADILRLWVAS--------TDYTGE--MA-VSDE-------ILKR 647
Cdd:PRK00133 315 TNVFAHGFlTVEG--AKMSKSRGTFIWARTYLDHLDPDYLRYYLAAklpetiddLDFNWEdfQQrVNSElvgkvvnFASR 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 648 AADsyrrirntarFLLANLNGFDPAKDMVKPeemvVLDRWAvgcakAAQEDILNAYEAYDFHEVVQRLMRFCSVemGSFY 727
Cdd:PRK00133 393 TAG----------FINKRFDGKLPDALADPE----LLEEFE-----AAAEKIAEAYEAREFRKALREIMALADF--ANKY 451
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 447209609 728 LD------IIKDrqyTAKAdsvARRSCQTALYhIAEALVRWMAPILSFTADEVWGYL 778
Cdd:PRK00133 452 VDdnepwkLAKQ---DGER---LQAVCSVGLN-LFRALAIYLKPVLPELAERAEAFL 501
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
585-632 |
1.23e-07 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 54.56 E-value: 1.23e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 447209609 585 PYRQVLTHGFtVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVAST 632
Cdd:cd00812 259 PPKGLIVQGM-VLLEGEKMSKSKGNVVTPDEAIKKYGADAARLYILFA 305
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
585-778 |
4.75e-07 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 53.65 E-value: 4.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 585 PYRQVLTHG-FTVDGQgrKMSKSIGNTVSPQDVMNKLGADILRLWV-------ASTDYTGEMAVSdeilkraadsyrRIr 656
Cdd:PRK12267 283 LPKKVFAHGwWLMKDG--KMSKSKGNVVDPEELVDRYGLDALRYYLlrevpfgSDGDFSPEALVE------------RI- 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 657 NtarFLLAN-----LNG--------FD---PAKDMVKPeemvvLDRWAVGCAKAAQEDILNAYEAYDFHEVVQRLMRFCS 720
Cdd:PRK12267 348 N---SDLANdlgnlLNRtvaminkyFDgeiPAPGNVTE-----FDEELIALAEETLKNYEELMEELQFSRALEEVWKLIS 419
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 447209609 721 VemGSFYLD------IIKDRQYTAKADSVarrscqtaLYHIAEALvRWMA----PILSFTADEVWGYL 778
Cdd:PRK12267 420 R--ANKYIDetapwvLAKDEGKKERLATV--------MYHLAESL-RKVAvllsPFMPETSKKIFEQL 476
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
582-626 |
4.24e-06 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 49.84 E-value: 4.24e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 447209609 582 GKAPYRQVLTHGF-TVDGQgrKMSKSIGNTVSPQDVMNKLGADILR 626
Cdd:cd00814 261 GLPLPTRIVAHGYlTVEGK--KMSKSRGNVVDPDDLLERYGADALR 304
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
58-192 |
7.12e-06 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 49.17 E-value: 7.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 58 PYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIElkveqeygkpgekfTAAEFRAKCREYAATQ-VDG 136
Cdd:cd00812 9 PYPSGALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFDAFGLPAE--------------NAAIKIGRDPEDWTEYnIKK 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 447209609 137 QRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCR 192
Cdd:cd00812 75 MKEQLKRMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNWCKLLD 130
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
59-110 |
2.01e-04 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 45.18 E-value: 2.01e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 447209609 59 YANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVE------QEY 110
Cdd:PRK12267 14 YPNGKPHIGHAYTTIAADALARYKRLQGYDVFFLTGTDEHGQKIQQAAEkagktpQEY 71
|
|
| Anticodon_Ia_Met |
cd07957 |
Anticodon-binding domain of methionyl tRNA synthetases; This domain is found in methionyl tRNA ... |
658-778 |
2.12e-04 |
|
Anticodon-binding domain of methionyl tRNA synthetases; This domain is found in methionyl tRNA synthetases (MetRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon (CAU). MetRS catalyzes the transfer of methionine to the 3'-end of its tRNA.
Pssm-ID: 153411 [Multi-domain] Cd Length: 129 Bit Score: 42.09 E-value: 2.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 658 TARFLLANLNGFDPAKDMVKPEEMVVLDRwavgcAKAAQEDILNAYEAYDFHEVVQRLMRFcsVEMGSFYLDiikDRQYT 737
Cdd:cd07957 16 TLNMASKYFGGVVPEFGGLTEEDEELLEE-----AEELLEEVAEAMEELEFRKALEEIMEL--ARAANKYID---ETAPW 85
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 447209609 738 AKADSVARRSCQTALYHIAEA---LVRWMAPILSFTADEVWGYL 778
Cdd:cd07957 86 KLAKEEDPERLATVLYVLLELlriLAILLSPFMPETAEKILDQL 129
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
49-200 |
6.42e-04 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 43.33 E-value: 6.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 49 KTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEyGKPGEKFT---AAEFRAk 125
Cdd:PRK11893 1 KKFYITTPIYYPNGKPHIGHAYTTLAADVLARFKRLRGYDVFFLTGTDEHGQKIQRKAEEA-GISPQELAdrnSAAFKR- 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 447209609 126 creyAATQVDGQRKDFIRlgvlgdwshpylTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEV 200
Cdd:PRK11893 79 ----LWEALNISYDDFIR------------TTDPRHKEAVQEIFQRLLANGDIYLGKYEGWYCVRCEEFYTESEL 137
|
|
| PLN02224 |
PLN02224 |
methionine-tRNA ligase |
522-626 |
1.26e-03 |
|
methionine-tRNA ligase
Pssm-ID: 177869 [Multi-domain] Cd Length: 616 Bit Score: 42.39 E-value: 1.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 447209609 522 DQYVKVPD----TLDVWFDS--GSTHSSVVDVRPEFA------GHAADMYLEGSDQHR--GWFMSSLMISTAMKgkAPyR 587
Cdd:PLN02224 276 DWGIPVPDddkqTIYVWFDAllGYISALTEDNKQQNLetavsfGWPASLHLIGKDILRfhAVYWPAMLMSAGLE--LP-K 352
|
90 100 110
....*....|....*....|....*....|....*....
gi 447209609 588 QVLTHGFtVDGQGRKMSKSIGNTVSPQDVMNKLGADILR 626
Cdd:PLN02224 353 MVFGHGF-LTKDGMKMGKSLGNTLEPFELVQKFGPDAVR 390
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
307-351 |
5.06e-03 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 39.07 E-value: 5.06e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 447209609 307 THPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGL 351
Cdd:pfam13603 90 IHPITGEKIPIWIANFVLMEYGTGAVMAVPAHDQRDFEFAKKYNL 134
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
587-631 |
5.60e-03 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 39.97 E-value: 5.60e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 447209609 587 RQVLTHGF-TVDGQgrKMSKSIGNTVSPQDVMNKLGADILRLWVAS 631
Cdd:pfam09334 310 TTVFAHGYlTYEGG--KMSKSRGNVVWPSEALDRFPPDALRYYLAR 353
|
|
| |
