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Conserved domains on  [gi|485650818|ref|WP_001296791|]
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MULTISPECIES: autotransporter outer membrane beta-barrel domain-containing protein [Enterobacteriaceae]

Protein Classification

autotransporter outer membrane beta-barrel domain-containing protein( domain architecture ID 10009446)

autotransporter outer membrane beta-barrel domain-containing protein similar to Escherichia coli uncharacterized protein YhjY

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YhjY super family cl44262
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
93-232 8.99e-18

Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];


The actual alignment was detected with superfamily member COG5571:

Pssm-ID: 444313 [Multi-domain]  Cd Length: 648  Bit Score: 81.46  E-value: 8.99e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818  93 MGWNFPLyEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLT--DPLWHASVSSLGWRVDSRL-GDLRPWAQISYNQQFGEN 169
Cdd:COG5571  500 AGYDFTA-GRLRTGPFAGLDYQKVKVDGYTETGAGSTALSfgDQDRDSLVGSLGWRADYQLlGRFNPYAEVAYEHEFGDD 578
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818 170 IWKAQSGLS-------RMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQAENTTNNSDYLYTMGVSARF 232
Cdd:COG5571  579 DRDVTAGLAslpagsfSLPAAAPDKNWGRATLGASAALTNGVSLFAGYSGTFGRDDGRQTSVNLGLSARF 648
 
Name Accession Description Interval E-value
YhjY COG5571
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
93-232 8.99e-18

Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];


Pssm-ID: 444313 [Multi-domain]  Cd Length: 648  Bit Score: 81.46  E-value: 8.99e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818  93 MGWNFPLyEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLT--DPLWHASVSSLGWRVDSRL-GDLRPWAQISYNQQFGEN 169
Cdd:COG5571  500 AGYDFTA-GRLRTGPFAGLDYQKVKVDGYTETGAGSTALSfgDQDRDSLVGSLGWRADYQLlGRFNPYAEVAYEHEFGDD 578
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818 170 IWKAQSGLS-------RMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQAENTTNNSDYLYTMGVSARF 232
Cdd:COG5571  579 DRDVTAGLAslpagsfSLPAAAPDKNWGRATLGASAALTNGVSLFAGYSGTFGRDDGRQTSVNLGLSARF 648
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
87-208 7.41e-06

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 45.84  E-value: 7.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818   87 VTSSMSMGWNFPLYEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPL-WHASVSSLGWRVDSRL----GDLRPWAQIS 161
Cdd:pfam03797 118 FGASLEAGYRFALGGGWTLEPFAGLAYVRLRLDGFTESGGAAALSVDSQsYDSLTGRLGLRLSYTFdlggGTLTPYARLG 197
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 485650818  162 YNQQFGENIWKAQSGLSRM--------TATNQNGNWLDVTVGADMLLNQNIAAYA 208
Cdd:pfam03797 198 WRHEFGDDDPVTTAAFAGLsgagsftvAGADLARDSLELGAGLSAQLSDNLSLYA 252
Autotransporter smart00869
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
87-213 2.27e-04

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.


Pssm-ID: 214872 [Multi-domain]  Cd Length: 268  Bit Score: 41.40  E-value: 2.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818    87 VTSSMSMGWNFPLYEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLT---DPLwHASVSSLGWRVDSRL-----GDLRPWA 158
Cdd:smart00869 121 YGASLEAGYRFYLGGGLTLTPFAGLAYSRVRQDGFTESGGGAFGLSvdsQSL-DSLSLPLGLRLEYRLalgdgATLTPYL 199
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 485650818   159 QISYNQQFGENIWKAQSGLS------RMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQA 213
Cdd:smart00869 200 RLAYVHDFYDDNPVVTASLLgsgasfTTSGTDLDRNAAELGLGLSAKLSNGLSLSLNYDGE 260
 
Name Accession Description Interval E-value
YhjY COG5571
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
93-232 8.99e-18

Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];


Pssm-ID: 444313 [Multi-domain]  Cd Length: 648  Bit Score: 81.46  E-value: 8.99e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818  93 MGWNFPLyEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLT--DPLWHASVSSLGWRVDSRL-GDLRPWAQISYNQQFGEN 169
Cdd:COG5571  500 AGYDFTA-GRLRTGPFAGLDYQKVKVDGYTETGAGSTALSfgDQDRDSLVGSLGWRADYQLlGRFNPYAEVAYEHEFGDD 578
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818 170 IWKAQSGLS-------RMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQAENTTNNSDYLYTMGVSARF 232
Cdd:COG5571  579 DRDVTAGLAslpagsfSLPAAAPDKNWGRATLGASAALTNGVSLFAGYSGTFGRDDGRQTSVNLGLSARF 648
Autotransporter pfam03797
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
87-208 7.41e-06

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.


Pssm-ID: 461054 [Multi-domain]  Cd Length: 255  Bit Score: 45.84  E-value: 7.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818   87 VTSSMSMGWNFPLYEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPL-WHASVSSLGWRVDSRL----GDLRPWAQIS 161
Cdd:pfam03797 118 FGASLEAGYRFALGGGWTLEPFAGLAYVRLRLDGFTESGGAAALSVDSQsYDSLTGRLGLRLSYTFdlggGTLTPYARLG 197
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 485650818  162 YNQQFGENIWKAQSGLSRM--------TATNQNGNWLDVTVGADMLLNQNIAAYA 208
Cdd:pfam03797 198 WRHEFGDDDPVTTAAFAGLsgagsftvAGADLARDSLELGAGLSAQLSDNLSLYA 252
Autotransporter smart00869
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
87-213 2.27e-04

Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.


Pssm-ID: 214872 [Multi-domain]  Cd Length: 268  Bit Score: 41.40  E-value: 2.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485650818    87 VTSSMSMGWNFPLYEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLT---DPLwHASVSSLGWRVDSRL-----GDLRPWA 158
Cdd:smart00869 121 YGASLEAGYRFYLGGGLTLTPFAGLAYSRVRQDGFTESGGGAFGLSvdsQSL-DSLSLPLGLRLEYRLalgdgATLTPYL 199
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 485650818   159 QISYNQQFGENIWKAQSGLS------RMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQA 213
Cdd:smart00869 200 RLAYVHDFYDDNPVVTASLLgsgasfTTSGTDLDRNAAELGLGLSAKLSNGLSLSLNYDGE 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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