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MULTISPECIES: VirB3 family type IV secretion system protein [Enterobacteriaceae]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
CagE_TrbE_VirB super family
cl40727 CagE, TrbE, VirB family, component of type IV transporter system; This family includes the ...
106-913
0e+00
CagE, TrbE, VirB family, component of type IV transporter system; This family includes the Helicobacter pylori protein CagE, which together with other proteins from the cag pathogenicity island (PAI), encodes a type IV transporter secretion system. The precise role of CagE is not known, but studies in animal models have shown that it is essential for pathogenesis in Helicobacter pylori induced gastritis and peptic ulceration. Indeed, the expression of the cag PAI has been shown to be essential for stimulating human gastric epithelial cell apoptosis in vitro. Similar type IV transport systems are also found in other bacteria. This family includes the TrbE and VirB proteins from the respective trb and Vir conjugal transfer systems in Agrobacterium tumefaciens. homologs of VirB proteins from other species are also members of this family, e.g. VirB from Brucella suis.
TIGR00929 :Pssm-ID: 454818 [Multi-domain]
Cd Length: 785
Bit Score: 568.87
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 106 KLKDQS S VEEL IPY SS H IT D NI I V TKN RD L LATWQID G AY FE CVDS EDL SI L TDQ LN TLIR S FEGKS V T L YP H RI R C K K - 184
Cdd:TIGR00929 1 HVPKEY S MSDF IPY AG H YD D HV I L TKN GS L MGIIKLE G IS FE SASD EDL NL L HRE LN AALK S IGSGQ V A L WV H TV R R K I v 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 185 -- DVR P V F NS ki P F VNRVMNDYYES F PQ S EFF EN K L F LT ICF KP FTTE d KVTH F FSR - G KK QKDI F KEPVN E MN E ICDR L 261
Cdd:TIGR00929 81 id YPD P E F KN -- G F AAAIDEEWRRK F AS S DLY EN D L Y LT LEY KP DSIG - VLEK F KKS l T KK TREE F QDNYR E TL E SIKA L 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 262 NTY ------- L SRFHSRR L GL Y EDH G VV YS DQ L SLFQY L LS G RWQK V RVSSS P F Y T -- Y LGGKDLF FG N D AGQ I TASDHA 332
Cdd:TIGR00929 158 EDI krnllel L REYGAEL L KE Y DKT G HI YS EL L EFLAF L VN G NDIP V TPPVI P G Y L ds Y IPSSEVL FG K D GFV I RSPKDN 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 333 R Y F RC I E IK D Y FQE T DA GIL D AL MY L PV E YVV T S SF TAMD K QS A IKA L DDQIDK L EMTD D A AKS LL A D L KVG LD MVS SG Y 412
Cdd:TIGR00929 238 R F F SV I S IK E Y PEK T EP GIL N AL LE L DC E FIL T H SF SFLS K EA A LSK L GRKRKR L ISKG D R AKS QI A E L DEA LD ELT SG D 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 413 ISF G KS H QT LVV F A DSP E R L VKDTNIVT S T L EDL G LIVTYS TL S L G AA YFA QLPGN YTLR PR L S TLS S L NFA EMES FHNF 492
Cdd:TIGR00929 318 FVM G EH H LS LVV Y A EDL E K L DAALREAR S L L NAC G IVAVIE TL G L E AA FWS QLPGN FSWN PR K S LIT S R NFA SLIP FHNF 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 493 FS GK EK GN T WG EK L IT L RGSGNDIYHL N Y H MTT ehqnffgk NPT LGHT E I L G TSNV GKT V LL mtk A F AAQ Q F gtpesfpa 572
Cdd:TIGR00929 398 NL GK LR GN P WG PA L TL L KTQSGTPFYF N F H VRD -------- AKV LGHT L I F G PTGS GKT T LL --- N F LLA Q M -------- 458
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 573 n R K LKKL T TVF FDKDR AG E VG IRA M GG S Y YRV K E GEP T G W NP AA L PP T K RN I AF M K DLVRL L C TL NSEPLD - DYQNSLI S 651
Cdd:TIGR00929 459 - Q K YGGM T IFA FDKDR GM E IF IRA F GG A Y LEI K D GEP F G F NP FQ L ED T E RN R AF L K EWLAM L V TL DGSTDI s AEDRNAL S 537
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 652 D A V e RLMQ R SDRS - YPI S K L RPLIQEP ddtetk RHG L KA RL K PW TQ G EEF GW V FDN RE D TF D VD nl DVF G I D G TE F LDN K 730
Cdd:TIGR00929 538 S A I - DTVY R EGPL i RSL S D L LNFLPKD ------ YID L AD RL E PW LK G GDY GW L FDN PT D DL D LS -- KIT G F D L TE L LDN P 608
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 731 VL A SAASF YL IY R VTMLA DGR RL LI YM DE F WQ WIN N EA F RDFVYNK LKT G RK LDMVL V V ATQS PDELIK S P IA AAVR EQC 810
Cdd:TIGR00929 609 KV A TPVLM YL FH R INEAL DGR PF LI II DE A WQ YLG N PV F AAKIRDW LKT L RK ANGIV V L ATQS INDALG S R IA DSIL EQC 688
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 811 AT H I Y L A NP K A K R SE Y VD G LQVR E LY F DKI K AIDPL SR Q FL v V K NP Q R kgesddf AAF A R L E LG KAAY YL P VLS ASKPQL 890
Cdd:TIGR00929 689 AT K I F L P NP E A D R ED Y AE G FKLT E RE F ELL K STPEE SR K FL - I K QG Q S ------- SVV A E L N LG GMDN YL R VLS SDTENV 760
810 820
....*....|....*....|....
gi 485721632 891 E LF D DIW KE - G MK P EE WL DTYLEQ 913
Cdd:TIGR00929 761 E II D ALI KE y G DD P DD WL PIFYRA 784
VirB3
COG3702 Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and ...
1-97
3.35e-20
Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442916
Cd Length: 97
Bit Score: 86.09
E-value: 3.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 1 MST LFKGLTRPA LI rg LGVPL Y PF LGMCIICVL L GV W IHE - AMYA L IL P GWYAI R RVTQF D E RFF D LL Y LR TLVKGHSLS 79
Cdd:COG3702 2 EDP LFKGLTRPA MF -- LGVPL V PF VLNVMVSLI L FI W TGS l LYLL L AI P LHFVL R LICRR D P RFF R LL L LR LRTRPRTRN 79
90
....*....|....*...
gi 485721632 80 NKRFSAVH Y AGSQ Y DEVD 97
Cdd:COG3702 80 RRFWGGNS Y SPLP Y RRRR 97
Name
Accession
Description
Interval
E-value
VirB4_CagE
TIGR00929 type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ...
106-913
0e+00
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).
Pssm-ID: 273346 [Multi-domain]
Cd Length: 785
Bit Score: 568.87
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 106 KLKDQS S VEEL IPY SS H IT D NI I V TKN RD L LATWQID G AY FE CVDS EDL SI L TDQ LN TLIR S FEGKS V T L YP H RI R C K K - 184
Cdd:TIGR00929 1 HVPKEY S MSDF IPY AG H YD D HV I L TKN GS L MGIIKLE G IS FE SASD EDL NL L HRE LN AALK S IGSGQ V A L WV H TV R R K I v 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 185 -- DVR P V F NS ki P F VNRVMNDYYES F PQ S EFF EN K L F LT ICF KP FTTE d KVTH F FSR - G KK QKDI F KEPVN E MN E ICDR L 261
Cdd:TIGR00929 81 id YPD P E F KN -- G F AAAIDEEWRRK F AS S DLY EN D L Y LT LEY KP DSIG - VLEK F KKS l T KK TREE F QDNYR E TL E SIKA L 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 262 NTY ------- L SRFHSRR L GL Y EDH G VV YS DQ L SLFQY L LS G RWQK V RVSSS P F Y T -- Y LGGKDLF FG N D AGQ I TASDHA 332
Cdd:TIGR00929 158 EDI krnllel L REYGAEL L KE Y DKT G HI YS EL L EFLAF L VN G NDIP V TPPVI P G Y L ds Y IPSSEVL FG K D GFV I RSPKDN 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 333 R Y F RC I E IK D Y FQE T DA GIL D AL MY L PV E YVV T S SF TAMD K QS A IKA L DDQIDK L EMTD D A AKS LL A D L KVG LD MVS SG Y 412
Cdd:TIGR00929 238 R F F SV I S IK E Y PEK T EP GIL N AL LE L DC E FIL T H SF SFLS K EA A LSK L GRKRKR L ISKG D R AKS QI A E L DEA LD ELT SG D 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 413 ISF G KS H QT LVV F A DSP E R L VKDTNIVT S T L EDL G LIVTYS TL S L G AA YFA QLPGN YTLR PR L S TLS S L NFA EMES FHNF 492
Cdd:TIGR00929 318 FVM G EH H LS LVV Y A EDL E K L DAALREAR S L L NAC G IVAVIE TL G L E AA FWS QLPGN FSWN PR K S LIT S R NFA SLIP FHNF 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 493 FS GK EK GN T WG EK L IT L RGSGNDIYHL N Y H MTT ehqnffgk NPT LGHT E I L G TSNV GKT V LL mtk A F AAQ Q F gtpesfpa 572
Cdd:TIGR00929 398 NL GK LR GN P WG PA L TL L KTQSGTPFYF N F H VRD -------- AKV LGHT L I F G PTGS GKT T LL --- N F LLA Q M -------- 458
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 573 n R K LKKL T TVF FDKDR AG E VG IRA M GG S Y YRV K E GEP T G W NP AA L PP T K RN I AF M K DLVRL L C TL NSEPLD - DYQNSLI S 651
Cdd:TIGR00929 459 - Q K YGGM T IFA FDKDR GM E IF IRA F GG A Y LEI K D GEP F G F NP FQ L ED T E RN R AF L K EWLAM L V TL DGSTDI s AEDRNAL S 537
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 652 D A V e RLMQ R SDRS - YPI S K L RPLIQEP ddtetk RHG L KA RL K PW TQ G EEF GW V FDN RE D TF D VD nl DVF G I D G TE F LDN K 730
Cdd:TIGR00929 538 S A I - DTVY R EGPL i RSL S D L LNFLPKD ------ YID L AD RL E PW LK G GDY GW L FDN PT D DL D LS -- KIT G F D L TE L LDN P 608
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 731 VL A SAASF YL IY R VTMLA DGR RL LI YM DE F WQ WIN N EA F RDFVYNK LKT G RK LDMVL V V ATQS PDELIK S P IA AAVR EQC 810
Cdd:TIGR00929 609 KV A TPVLM YL FH R INEAL DGR PF LI II DE A WQ YLG N PV F AAKIRDW LKT L RK ANGIV V L ATQS INDALG S R IA DSIL EQC 688
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 811 AT H I Y L A NP K A K R SE Y VD G LQVR E LY F DKI K AIDPL SR Q FL v V K NP Q R kgesddf AAF A R L E LG KAAY YL P VLS ASKPQL 890
Cdd:TIGR00929 689 AT K I F L P NP E A D R ED Y AE G FKLT E RE F ELL K STPEE SR K FL - I K QG Q S ------- SVV A E L N LG GMDN YL R VLS SDTENV 760
810 820
....*....|....*....|....
gi 485721632 891 E LF D DIW KE - G MK P EE WL DTYLEQ 913
Cdd:TIGR00929 761 E II D ALI KE y G DD P DD WL PIFYRA 784
VirB4
COG3451 Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ...
333-900
2.06e-136
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442674 [Multi-domain]
Cd Length: 546
Bit Score: 418.58
E-value: 2.06e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 333 RY F R CIE IK D Y FQ ET DA G I LD A L MY LP V E YV VT S SFT AM DK QS A I K A L DDQIDK LE -------- MT DD A A K S LLA D LKVG 404
Cdd:COG3451 8 RY G R VLS IK G Y PS ET SP G L LD P L LQ LP C E FI VT Q SFT PL DK DE A L K K L KRKRRR LE skrkseqa LV DD D A E S QAE D AEEA 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 405 LD MVS SG YISF G KS H Q TL V VFAD SP E R L VKDTNI V T S T L EDL G LIVTYS TL SLGA A YFAQ LPGN YTL R P R LST L SSL N F A 484
Cdd:COG3451 88 LD ELQ SG GERL G EV H L TL T VFAD DL E E L EEAVRE V E S A L QSA G FTLVRE TL NQEE A FLSS LPGN FDY R L R RRL L TTS N L A 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 485 EMES FH N F FS G KEK G ntwgek LIT L RGSGNDIYHLNY H MTT ehqnffgknp TL G H T E ILG T S NV GK TV LL MTKAFAAQQF 564
Cdd:COG3451 168 ALFP FH S F EL G DPW G ------ IYL L NTRSGTPVFFDF H DGL ---------- DN G N T L ILG P S GS GK SF LL KLLLLQLLRY 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 565 G T pesfpanrklkkl TT V F FD KDRAG E VGI RA M GG S Y YRVKE G E PTG W NP AA L PP T KRNIA F MKD L VR LL CTLNS EPL DD 644
Cdd:COG3451 232 G A ------------- RI V I FD PGGSY E ILV RA L GG T Y IDLSP G S PTG L NP FD L ED T EEKRD F LLE L LE LL LGREG EPL TP 298
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 645 YQNSL I SD AV ER L MQ R S D RSYP -- I S K L RP L IQ E PDDTE tkrh G L K ARL K P W T Q G EEF GW V FD NRE d TF D VDNLDVFGI D 722
Cdd:COG3451 299 EERAA I DR AV RA L YR R A D PEER tt L S D L YE L LK E QPEAK ---- D L A ARL E P Y T K G GSY GW L FD GPT - NL D LSDARFVVF D 373
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 723 G TE F LDN KV L ASAASF YL IY R V ---- TMLA DGR RL LI YM DE F W QWIN N E AF RD F VYNK LKT G RK LDMVLVV ATQS PDELI 798
Cdd:COG3451 374 L TE L LDN PE L RPPVLL YL LH R I wnrl RKNN DGR PT LI VI DE A W LLLD N P AF AE F LEEW LKT L RK YNGAVIF ATQS VEDFL 453
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 799 K SPIA A A VR E QC AT H I Y L AN PKA KRSE Y VDG L QVR E LYFDK I KAIDPLS R Q FL VV knpqrkge SDDFAAFA RL E L G ka AY 878
Cdd:COG3451 454 S SPIA E A II E NS AT K I L L PQ PKA DIED Y AEL L GLS E RELEL I RSAGRGK R D FL IK -------- QGNGSVVF RL D L S -- PE 523
570 580
....*....|....*....|..
gi 485721632 879 Y L PV LS ASKPQLELF D DIWK E G 900
Cdd:COG3451 524 E L AL LS TKPEEVAIL D ELRA E H 545
PRK13898
PRK13898 type IV secretion system ATPase VirB4; Provisional
99-914
4.88e-116
type IV secretion system ATPase VirB4; Provisional
Pssm-ID: 172418
Cd Length: 800
Bit Score: 373.33
E-value: 4.88e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 99 SKVDNFMKL K DQSSVEEL IPY SS H ITDNI I V TK NRD LL ATWQID G AY FE CV D S EDL S I LTDQL N T L IR S FEGK S VT LY P H 178
Cdd:PRK13898 6 TRAAKEKRS K RERHTSHF IPY KC H WNSST I L TK DNS LL KVIKLS G FA FE TA D D EDL D I QKNIR N Q L LK S MSSG S FG LY F H 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 179 R IR CK K D V -- RPVFNS K I P -- F VNR V MNDYYESFPQSEF F E N K L FL TI CF KP F T -- T E ------ D K VTHFFSRGKKQK D I 246
Cdd:PRK13898 86 T IR RR K A V fs DDFPTV K V P nd F ATY V NVEWRKKHATKQS F F N E L YI TI LR KP D T kg V E ileyfl K K LRQKSNKEAWEN D M 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 247 f KE PVNEMN E ICD R LN T Y L SRFHS R R LG LYEDHGV V YSDQ L S - L FQYLLS G RWQK - V RVSSSPFYT YL GGKD LFFG NDAG 324
Cdd:PRK13898 166 - KE MYENLE E MTN R VV T S L RNYGP R L LG VRQTPSG V FCEI L E f L SSIVNC G DSPG p V ALPRGTIDE YL PTHR LFFG SKTI 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 325 QITASDHAR Y FRC I E IK D Y FQE T D AG I LD ALMY LP V E YVV T S SF TAMDK Q S AI KALDD Q IDKLEMTD D A A K S LL A DLKVG 404
Cdd:PRK13898 245 EAVSHNESK Y AGI I S IK E Y GPN T S AG M LD GFLQ LP Y E FII T Q SF QFTNR Q V AI GKMQL Q QNRMIQSG D K A V S QI A EISTA 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 405 LD MVS SG Y I S FG KS H Q T LVVFADSPER L VKDTNIVTST L EDL G LIVTYSTLS L GA A YF AQLPGN YTLRP R LS T L S S LN F A 484
Cdd:PRK13898 325 LD DAT SG D I A FG EH H L T ILCIEKNIKA L ENALSLAEVE L SNC G VYPVREKVN L EP A FW AQLPGN FDYIV R KA T I S T LN M A 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 485 EME S F HN FFS GK EKG N T WGE KLITLRGSGNDIYHL N Y H MT tehqnffgknp TL GHT E I L G TSNV GKTVL LMTKAFA A QQ F 564
Cdd:PRK13898 405 GFA S Q HN YPL GK KFD N H WGE AVTVFDTTSGTPFYF N F H VR ----------- DV GHT L I I G PTGA GKTVL MNFLCAQ A MK F 473
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 565 g T P ES F panrklkklttv FFDKDR AG E VG IRA MG G S Y YRVKEGEPTGW NP AA L PP T KR N IA F MKDLVRL L C T L N S E P L DD 644
Cdd:PRK13898 474 - S P RM F ------------ FFDKDR GA E IF IRA LN G V Y TVIEPRLKCNF NP LQ L DD T SE N RT F LMEWLKV L V T S N G E S L TA 540
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 645 YQNSL I S DAVE --- R L m QRS DR S yp I S K L RPL -- I QE P DD tetkrhg L KA R LKP W TQGEEFGWV FDN R ED TF D VDNLD VF 719
Cdd:PRK13898 541 QDIKR I N DAVE gnf K L - KKE DR R -- L S N L VAF lg I DG P NT ------- L AG R IAM W HGKGSHAAI FDN E ED LL D FQKAR VF 610
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 720 G IDGT E F L DNK V LASAASF YL IY R VTMLA DG RRLL I YM DE F W QW I N N EA F RDFVYNK LK TG RKL DMVLVV ATQS PDELI K 799
Cdd:PRK13898 611 G FEMG E L L KDP V SLAPVLL YL FH R ISISL DG TPSM I VL DE A W AL I D N PV F APKIKDW LK VL RKL NTFVIF ATQS VEDAS K 690
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 800 S P I AAAVRE Q C AT H I Y L A N P KA K r SE Y VDGLQVR E LYFDK IK AI DP LS R Q FL V vknpq RK G E S ddf A AF AR LE L GKAAYY 879
Cdd:PRK13898 691 S A I SDTLVQ Q T AT Q I F L P N L KA T - DI Y RSVFMLS E REYIL IK HT DP TT R F FL I ----- KQ G V S --- A VV AR IN L DGMDDI 761
810 820 830
....*....|....*....|....*....|....*.
gi 485721632 880 LP VLS ASKPQLE L F D D I WK E - G MK P EE WL DTYL E QA 914
Cdd:PRK13898 762 IS VLS GRAETVL L L D Q I RE E v G DD P NK WL PIFY E AV 797
CagE_TrbE_VirB
pfam03135 CagE, TrbE, VirB family, component of type IV transporter system; This family includes the ...
273-474
1.72e-41
CagE, TrbE, VirB family, component of type IV transporter system; This family includes the Helicobacter pylori protein CagE, which together with other proteins from the cag pathogenicity island (PAI), encodes a type IV transporter secretion system. The precise role of CagE is not known, but studies in animal models have shown that it is essential for pathogenesis in Helicobacter pylori induced gastritis and peptic ulceration. Indeed, the expression of the cag PAI has been shown to be essential for stimulating human gastric epithelial cell apoptosis in vitro. Similar type IV transport systems are also found in other bacteria. This family includes the TrbE and VirB proteins from the respective trb and Vir conjugal transfer systems in Agrobacterium tumefaciens. homologs of VirB proteins from other species are also members of this family, e.g. VirB from Brucella suis.
Pssm-ID: 367350 [Multi-domain]
Cd Length: 202
Bit Score: 150.96
E-value: 1.72e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 273 L GL Y EDH GV V YS DQ L SLFQY L LS G RWQK VR VSSSPFY - T Y L G GKDLF FG N D AGQ I TASDHAR Y FRC I E IK D Y FQ ET DA G I 351
Cdd:pfam03135 1 L SE Y GKR GV I YS EL L EFYNF L IN G ENHP VR LPRGMYL d E Y I G TSRVP FG K D KFI I RTAKDEK Y PSI I S IK E Y PP ET RS G L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 352 LD ALMY L PV E YVV T S SF TAMD KQ S A IKA L DDQID KL EMT DDA a KS LLAD L KVGL D M V S SG YISF G KS H QT LV V FA DSP E R 431
Cdd:pfam03135 81 LD KFLD L DE E LII T Q SF SFKN KQ K A LSF L KFTSR KL SIS DDA - KS QIME L EDAI D E V R SG DFAL G LY H NS LV L FA EDK E K 159
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 485721632 432 L VKDTNIV TS T L EDL G LIVTYS T LSLGA A Y F A QLPGN YT L RP R 474
Cdd:pfam03135 160 L DASVSEA TS L L NAK G FVAVIE T IGMEP A F F S QLPGN IR L NF R 202
VirB3
COG3702 Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and ...
1-97
3.35e-20
Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442916
Cd Length: 97
Bit Score: 86.09
E-value: 3.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 1 MST LFKGLTRPA LI rg LGVPL Y PF LGMCIICVL L GV W IHE - AMYA L IL P GWYAI R RVTQF D E RFF D LL Y LR TLVKGHSLS 79
Cdd:COG3702 2 EDP LFKGLTRPA MF -- LGVPL V PF VLNVMVSLI L FI W TGS l LYLL L AI P LHFVL R LICRR D P RFF R LL L LR LRTRPRTRN 79
90
....*....|....*...
gi 485721632 80 NKRFSAVH Y AGSQ Y DEVD 97
Cdd:COG3702 80 RRFWGGNS Y SPLP Y RRRR 97
VirB3
pfam05101 Type IV secretory pathway, VirB3-like protein; This family includes the Type IV secretory ...
2-83
6.80e-13
Type IV secretory pathway, VirB3-like protein; This family includes the Type IV secretory pathway VirB3 protein, that is found associated with bacterial inner and outer membranes. The family also includes the conjugal transfer protein TrbD family that contains a nucleotide binding motif and may provide energy for the export of DNA or the export of other Trb proteins.
Pssm-ID: 428303
Cd Length: 82
Bit Score: 64.95
E-value: 6.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 2 ST LFK G LTRPA LI rg LGVPL YP FL GMCIIC V L L G - V WIHEAMYA L IL P GWYAI R RVTQF D E R F F DL L Y L RTLVKGHSL s N 80
Cdd:pfam05101 1 DP LFK A LTRPA MF -- LGVPL EL FL LNGMVS V I L F l V GLSLWYLL L AP P LHLVL R LIAKR D P R M F RV L L L WLQTRPRLR - N 77
...
gi 485721632 81 K RF 83
Cdd:pfam05101 78 R RF 80
PRK13854
PRK13854 type IV secretion system protein VirB3; Provisional
2-80
2.62e-03
type IV secretion system protein VirB3; Provisional
Pssm-ID: 139914
Cd Length: 108
Bit Score: 38.27
E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 2 S TL FKGL TRPAL I rg LGVPL YPFLGMCIICVLLG V WIHEAM Y - ALI LP G W YAI R R V TQF D ERFFD -- LL Y LRT lv K G H S L 78
Cdd:PRK13854 8 A TL YLAA TRPAL F -- LGVPL TLAGVFMMLAGFVI V IVQNPL Y e VVL LP L W FGA R L V VER D YNAAS vv LL F LRT -- A G R S V 83
..
gi 485721632 79 SN 80
Cdd:PRK13854 84 DG 85
Name
Accession
Description
Interval
E-value
VirB4_CagE
TIGR00929 type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ...
106-913
0e+00
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).
Pssm-ID: 273346 [Multi-domain]
Cd Length: 785
Bit Score: 568.87
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 106 KLKDQS S VEEL IPY SS H IT D NI I V TKN RD L LATWQID G AY FE CVDS EDL SI L TDQ LN TLIR S FEGKS V T L YP H RI R C K K - 184
Cdd:TIGR00929 1 HVPKEY S MSDF IPY AG H YD D HV I L TKN GS L MGIIKLE G IS FE SASD EDL NL L HRE LN AALK S IGSGQ V A L WV H TV R R K I v 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 185 -- DVR P V F NS ki P F VNRVMNDYYES F PQ S EFF EN K L F LT ICF KP FTTE d KVTH F FSR - G KK QKDI F KEPVN E MN E ICDR L 261
Cdd:TIGR00929 81 id YPD P E F KN -- G F AAAIDEEWRRK F AS S DLY EN D L Y LT LEY KP DSIG - VLEK F KKS l T KK TREE F QDNYR E TL E SIKA L 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 262 NTY ------- L SRFHSRR L GL Y EDH G VV YS DQ L SLFQY L LS G RWQK V RVSSS P F Y T -- Y LGGKDLF FG N D AGQ I TASDHA 332
Cdd:TIGR00929 158 EDI krnllel L REYGAEL L KE Y DKT G HI YS EL L EFLAF L VN G NDIP V TPPVI P G Y L ds Y IPSSEVL FG K D GFV I RSPKDN 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 333 R Y F RC I E IK D Y FQE T DA GIL D AL MY L PV E YVV T S SF TAMD K QS A IKA L DDQIDK L EMTD D A AKS LL A D L KVG LD MVS SG Y 412
Cdd:TIGR00929 238 R F F SV I S IK E Y PEK T EP GIL N AL LE L DC E FIL T H SF SFLS K EA A LSK L GRKRKR L ISKG D R AKS QI A E L DEA LD ELT SG D 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 413 ISF G KS H QT LVV F A DSP E R L VKDTNIVT S T L EDL G LIVTYS TL S L G AA YFA QLPGN YTLR PR L S TLS S L NFA EMES FHNF 492
Cdd:TIGR00929 318 FVM G EH H LS LVV Y A EDL E K L DAALREAR S L L NAC G IVAVIE TL G L E AA FWS QLPGN FSWN PR K S LIT S R NFA SLIP FHNF 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 493 FS GK EK GN T WG EK L IT L RGSGNDIYHL N Y H MTT ehqnffgk NPT LGHT E I L G TSNV GKT V LL mtk A F AAQ Q F gtpesfpa 572
Cdd:TIGR00929 398 NL GK LR GN P WG PA L TL L KTQSGTPFYF N F H VRD -------- AKV LGHT L I F G PTGS GKT T LL --- N F LLA Q M -------- 458
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 573 n R K LKKL T TVF FDKDR AG E VG IRA M GG S Y YRV K E GEP T G W NP AA L PP T K RN I AF M K DLVRL L C TL NSEPLD - DYQNSLI S 651
Cdd:TIGR00929 459 - Q K YGGM T IFA FDKDR GM E IF IRA F GG A Y LEI K D GEP F G F NP FQ L ED T E RN R AF L K EWLAM L V TL DGSTDI s AEDRNAL S 537
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 652 D A V e RLMQ R SDRS - YPI S K L RPLIQEP ddtetk RHG L KA RL K PW TQ G EEF GW V FDN RE D TF D VD nl DVF G I D G TE F LDN K 730
Cdd:TIGR00929 538 S A I - DTVY R EGPL i RSL S D L LNFLPKD ------ YID L AD RL E PW LK G GDY GW L FDN PT D DL D LS -- KIT G F D L TE L LDN P 608
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 731 VL A SAASF YL IY R VTMLA DGR RL LI YM DE F WQ WIN N EA F RDFVYNK LKT G RK LDMVL V V ATQS PDELIK S P IA AAVR EQC 810
Cdd:TIGR00929 609 KV A TPVLM YL FH R INEAL DGR PF LI II DE A WQ YLG N PV F AAKIRDW LKT L RK ANGIV V L ATQS INDALG S R IA DSIL EQC 688
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 811 AT H I Y L A NP K A K R SE Y VD G LQVR E LY F DKI K AIDPL SR Q FL v V K NP Q R kgesddf AAF A R L E LG KAAY YL P VLS ASKPQL 890
Cdd:TIGR00929 689 AT K I F L P NP E A D R ED Y AE G FKLT E RE F ELL K STPEE SR K FL - I K QG Q S ------- SVV A E L N LG GMDN YL R VLS SDTENV 760
810 820
....*....|....*....|....
gi 485721632 891 E LF D DIW KE - G MK P EE WL DTYLEQ 913
Cdd:TIGR00929 761 E II D ALI KE y G DD P DD WL PIFYRA 784
VirB4
COG3451 Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ...
333-900
2.06e-136
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442674 [Multi-domain]
Cd Length: 546
Bit Score: 418.58
E-value: 2.06e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 333 RY F R CIE IK D Y FQ ET DA G I LD A L MY LP V E YV VT S SFT AM DK QS A I K A L DDQIDK LE -------- MT DD A A K S LLA D LKVG 404
Cdd:COG3451 8 RY G R VLS IK G Y PS ET SP G L LD P L LQ LP C E FI VT Q SFT PL DK DE A L K K L KRKRRR LE skrkseqa LV DD D A E S QAE D AEEA 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 405 LD MVS SG YISF G KS H Q TL V VFAD SP E R L VKDTNI V T S T L EDL G LIVTYS TL SLGA A YFAQ LPGN YTL R P R LST L SSL N F A 484
Cdd:COG3451 88 LD ELQ SG GERL G EV H L TL T VFAD DL E E L EEAVRE V E S A L QSA G FTLVRE TL NQEE A FLSS LPGN FDY R L R RRL L TTS N L A 167
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 485 EMES FH N F FS G KEK G ntwgek LIT L RGSGNDIYHLNY H MTT ehqnffgknp TL G H T E ILG T S NV GK TV LL MTKAFAAQQF 564
Cdd:COG3451 168 ALFP FH S F EL G DPW G ------ IYL L NTRSGTPVFFDF H DGL ---------- DN G N T L ILG P S GS GK SF LL KLLLLQLLRY 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 565 G T pesfpanrklkkl TT V F FD KDRAG E VGI RA M GG S Y YRVKE G E PTG W NP AA L PP T KRNIA F MKD L VR LL CTLNS EPL DD 644
Cdd:COG3451 232 G A ------------- RI V I FD PGGSY E ILV RA L GG T Y IDLSP G S PTG L NP FD L ED T EEKRD F LLE L LE LL LGREG EPL TP 298
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 645 YQNSL I SD AV ER L MQ R S D RSYP -- I S K L RP L IQ E PDDTE tkrh G L K ARL K P W T Q G EEF GW V FD NRE d TF D VDNLDVFGI D 722
Cdd:COG3451 299 EERAA I DR AV RA L YR R A D PEER tt L S D L YE L LK E QPEAK ---- D L A ARL E P Y T K G GSY GW L FD GPT - NL D LSDARFVVF D 373
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 723 G TE F LDN KV L ASAASF YL IY R V ---- TMLA DGR RL LI YM DE F W QWIN N E AF RD F VYNK LKT G RK LDMVLVV ATQS PDELI 798
Cdd:COG3451 374 L TE L LDN PE L RPPVLL YL LH R I wnrl RKNN DGR PT LI VI DE A W LLLD N P AF AE F LEEW LKT L RK YNGAVIF ATQS VEDFL 453
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 799 K SPIA A A VR E QC AT H I Y L AN PKA KRSE Y VDG L QVR E LYFDK I KAIDPLS R Q FL VV knpqrkge SDDFAAFA RL E L G ka AY 878
Cdd:COG3451 454 S SPIA E A II E NS AT K I L L PQ PKA DIED Y AEL L GLS E RELEL I RSAGRGK R D FL IK -------- QGNGSVVF RL D L S -- PE 523
570 580
....*....|....*....|..
gi 485721632 879 Y L PV LS ASKPQLELF D DIWK E G 900
Cdd:COG3451 524 E L AL LS TKPEEVAIL D ELRA E H 545
PRK13898
PRK13898 type IV secretion system ATPase VirB4; Provisional
99-914
4.88e-116
type IV secretion system ATPase VirB4; Provisional
Pssm-ID: 172418
Cd Length: 800
Bit Score: 373.33
E-value: 4.88e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 99 SKVDNFMKL K DQSSVEEL IPY SS H ITDNI I V TK NRD LL ATWQID G AY FE CV D S EDL S I LTDQL N T L IR S FEGK S VT LY P H 178
Cdd:PRK13898 6 TRAAKEKRS K RERHTSHF IPY KC H WNSST I L TK DNS LL KVIKLS G FA FE TA D D EDL D I QKNIR N Q L LK S MSSG S FG LY F H 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 179 R IR CK K D V -- RPVFNS K I P -- F VNR V MNDYYESFPQSEF F E N K L FL TI CF KP F T -- T E ------ D K VTHFFSRGKKQK D I 246
Cdd:PRK13898 86 T IR RR K A V fs DDFPTV K V P nd F ATY V NVEWRKKHATKQS F F N E L YI TI LR KP D T kg V E ileyfl K K LRQKSNKEAWEN D M 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 247 f KE PVNEMN E ICD R LN T Y L SRFHS R R LG LYEDHGV V YSDQ L S - L FQYLLS G RWQK - V RVSSSPFYT YL GGKD LFFG NDAG 324
Cdd:PRK13898 166 - KE MYENLE E MTN R VV T S L RNYGP R L LG VRQTPSG V FCEI L E f L SSIVNC G DSPG p V ALPRGTIDE YL PTHR LFFG SKTI 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 325 QITASDHAR Y FRC I E IK D Y FQE T D AG I LD ALMY LP V E YVV T S SF TAMDK Q S AI KALDD Q IDKLEMTD D A A K S LL A DLKVG 404
Cdd:PRK13898 245 EAVSHNESK Y AGI I S IK E Y GPN T S AG M LD GFLQ LP Y E FII T Q SF QFTNR Q V AI GKMQL Q QNRMIQSG D K A V S QI A EISTA 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 405 LD MVS SG Y I S FG KS H Q T LVVFADSPER L VKDTNIVTST L EDL G LIVTYSTLS L GA A YF AQLPGN YTLRP R LS T L S S LN F A 484
Cdd:PRK13898 325 LD DAT SG D I A FG EH H L T ILCIEKNIKA L ENALSLAEVE L SNC G VYPVREKVN L EP A FW AQLPGN FDYIV R KA T I S T LN M A 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 485 EME S F HN FFS GK EKG N T WGE KLITLRGSGNDIYHL N Y H MT tehqnffgknp TL GHT E I L G TSNV GKTVL LMTKAFA A QQ F 564
Cdd:PRK13898 405 GFA S Q HN YPL GK KFD N H WGE AVTVFDTTSGTPFYF N F H VR ----------- DV GHT L I I G PTGA GKTVL MNFLCAQ A MK F 473
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 565 g T P ES F panrklkklttv FFDKDR AG E VG IRA MG G S Y YRVKEGEPTGW NP AA L PP T KR N IA F MKDLVRL L C T L N S E P L DD 644
Cdd:PRK13898 474 - S P RM F ------------ FFDKDR GA E IF IRA LN G V Y TVIEPRLKCNF NP LQ L DD T SE N RT F LMEWLKV L V T S N G E S L TA 540
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 645 YQNSL I S DAVE --- R L m QRS DR S yp I S K L RPL -- I QE P DD tetkrhg L KA R LKP W TQGEEFGWV FDN R ED TF D VDNLD VF 719
Cdd:PRK13898 541 QDIKR I N DAVE gnf K L - KKE DR R -- L S N L VAF lg I DG P NT ------- L AG R IAM W HGKGSHAAI FDN E ED LL D FQKAR VF 610
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 720 G IDGT E F L DNK V LASAASF YL IY R VTMLA DG RRLL I YM DE F W QW I N N EA F RDFVYNK LK TG RKL DMVLVV ATQS PDELI K 799
Cdd:PRK13898 611 G FEMG E L L KDP V SLAPVLL YL FH R ISISL DG TPSM I VL DE A W AL I D N PV F APKIKDW LK VL RKL NTFVIF ATQS VEDAS K 690
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 800 S P I AAAVRE Q C AT H I Y L A N P KA K r SE Y VDGLQVR E LYFDK IK AI DP LS R Q FL V vknpq RK G E S ddf A AF AR LE L GKAAYY 879
Cdd:PRK13898 691 S A I SDTLVQ Q T AT Q I F L P N L KA T - DI Y RSVFMLS E REYIL IK HT DP TT R F FL I ----- KQ G V S --- A VV AR IN L DGMDDI 761
810 820 830
....*....|....*....|....*....|....*.
gi 485721632 880 LP VLS ASKPQLE L F D D I WK E - G MK P EE WL DTYL E QA 914
Cdd:PRK13898 762 IS VLS GRAETVL L L D Q I RE E v G DD P NK WL PIFY E AV 797
PRK13853
PRK13853 type IV secretion system protein VirB4; Provisional
110-911
1.44e-98
type IV secretion system protein VirB4; Provisional
Pssm-ID: 139913 [Multi-domain]
Cd Length: 789
Bit Score: 326.43
E-value: 1.44e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 110 QS S V E ELI PY SS H IT D N I IVTKNRDLLATWQ I D G AY FE CVDS E DLSILTDQL NTL I R SFEGKS V TL Y P H RI R c KK DV R P - 188
Cdd:PRK13853 9 ER S G E IYL PY VG H LS D H I VLLEDGSIMTMAH I S G LP FE LEEV E MRNARCRAF NTL L R NIADDN V SI Y A H LV R - HN DV P P p 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 189 --- V F N S K ip F VNRVMNDYY E SFPQSEFFE N KL FLT ICFK P F T TED KV THF F SR -- GKK QK D I f KEPVNEMNEICDRLNT 263
Cdd:PRK13853 88 par H F R S A -- F AASLSEAFE E RVLSGKLLR N DH FLT LIVS P R T ALG KV KRR F TK ry GKK EN D L - AGQIRNLEDLWHVVAG 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 264 Y L SRFHS RRLG LY E DHG V VYSDQLSLFQYLLS GR WQK V R V S S SPFYTYLGGKDLFF G NDAGQ I TASDHARYFRCIEIKD Y 343
Cdd:PRK13853 165 A L DAYGL RRLG IR E KQQ V LFTEIGEALRLIMT GR FTP V P V V S GSLGASIYTDRVIC G KRGLE I RTPKDSYVGSIFSFRE Y 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 344 FQE T DA G I L DA L MY L PVEY V V T S SF TAMDKQS A IKA L DDQIDKLEMTD D A A KSLLAD L KVGL D MVS S GYISF G KS H QT L V 423
Cdd:PRK13853 245 PAK T RP G M L NT L LS L DFPL V L T Q SF SFLTRAQ A HAK L SLKSSQMTSSG D K A VTQISE L AEAE D ALA S NEFVM G SH H LS L C 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 424 V F AD SPER L VKDTNIVTST L E D L G LI V TYSTLSLG AAY FA QLPGN YTL R P R LSTLS S L NFA EME SF H NF FS G KEK G N t WG 503
Cdd:PRK13853 325 V Y AD DLNS L ADRGARARTR L A D A G AV V VQEGIGME AAY WS QLPGN HKW R T R PGAIT S R NFA GLV SF E NF PE G ARS G H - WG 403
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 504 EKLITL R GS G NDIYHLNY H mtt EH Q nffgknpt L G H T E I L G TSNV GKT V L LM tka F AAQQF gt PE S FPA nrkl KKLTT VF 583
Cdd:PRK13853 404 NAIARF R TN G GTPFDYIP H --- EH D -------- V G M T A I F G PIGR GKT T L MT --- F ILAML -- EQ S MVD ---- RAGAV VF 463
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 584 FDKDR A GE VGI RA M GG S Y YRVKE G E P T G WN P - AA L PP T KRNIA F MKD - L V R L LCTLNSEPLDDYQ N SLISDAVE R LMQRS 661
Cdd:PRK13853 464 FDKDR G GE LLV RA T GG T Y LALRR G V P S G LA P l RG L EN T AASRD F LRE w I V A L IESDGRGGISPEE N RRLVRGIQ R QLSFD 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 662 DRSYPISK LR P - L IQE P DD tetkrh G LK ARL KP W TQ G EEF GW V FD NRE D TFDV D N l DVF G I D G T EF L DNKVLASA A SF YL 740
Cdd:PRK13853 544 PNMRSLAG LR E f L LHG P AE ------ G AG ARL QR W CR G NAL GW A FD GEV D EVKL D P - SIT G F D M T HL L EYEEVCAP A AA YL 616
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 741 IY R VTMLA DGRR LLIYM DEF WQWIN N EA F RDF V YNK L K T G RK LDMV L VV ATQ S P DELIK SP IA A AVRE QC A T H I YLAN P K 820
Cdd:PRK13853 617 LH R IGAMV DGRR FVMSC DEF RAYLL N PK F AAV V DKF L L T V RK NNGM L IL ATQ Q P EHVLE SP LG A SLVA QC M T K I FYPS P T 696
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 821 A K RS E Y V DGL QVR E LY F DK I KA - IDPL SR Q FL V vknp Q R KGE S ddfa AFARLE L GKAAY Y LP VLS ASKPQLELF D DIWK - 898
Cdd:PRK13853 697 A D RS A Y I DGL KCT E KE F QA I RE d MAVG SR K FL L ---- K R ESG S ---- VICEFD L RDMRE Y VA VLS GRANTVRFA D QLRE t 768
810
....*....|...
gi 485721632 899 E G MK P EE WL DTYL 911
Cdd:PRK13853 769 H G DD P SA WL SEFM 781
CagE_TrbE_VirB
pfam03135 CagE, TrbE, VirB family, component of type IV transporter system; This family includes the ...
273-474
1.72e-41
CagE, TrbE, VirB family, component of type IV transporter system; This family includes the Helicobacter pylori protein CagE, which together with other proteins from the cag pathogenicity island (PAI), encodes a type IV transporter secretion system. The precise role of CagE is not known, but studies in animal models have shown that it is essential for pathogenesis in Helicobacter pylori induced gastritis and peptic ulceration. Indeed, the expression of the cag PAI has been shown to be essential for stimulating human gastric epithelial cell apoptosis in vitro. Similar type IV transport systems are also found in other bacteria. This family includes the TrbE and VirB proteins from the respective trb and Vir conjugal transfer systems in Agrobacterium tumefaciens. homologs of VirB proteins from other species are also members of this family, e.g. VirB from Brucella suis.
Pssm-ID: 367350 [Multi-domain]
Cd Length: 202
Bit Score: 150.96
E-value: 1.72e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 273 L GL Y EDH GV V YS DQ L SLFQY L LS G RWQK VR VSSSPFY - T Y L G GKDLF FG N D AGQ I TASDHAR Y FRC I E IK D Y FQ ET DA G I 351
Cdd:pfam03135 1 L SE Y GKR GV I YS EL L EFYNF L IN G ENHP VR LPRGMYL d E Y I G TSRVP FG K D KFI I RTAKDEK Y PSI I S IK E Y PP ET RS G L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 352 LD ALMY L PV E YVV T S SF TAMD KQ S A IKA L DDQID KL EMT DDA a KS LLAD L KVGL D M V S SG YISF G KS H QT LV V FA DSP E R 431
Cdd:pfam03135 81 LD KFLD L DE E LII T Q SF SFKN KQ K A LSF L KFTSR KL SIS DDA - KS QIME L EDAI D E V R SG DFAL G LY H NS LV L FA EDK E K 159
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 485721632 432 L VKDTNIV TS T L EDL G LIVTYS T LSLGA A Y F A QLPGN YT L RP R 474
Cdd:pfam03135 160 L DASVSEA TS L L NAK G FVAVIE T IGMEP A F F S QLPGN IR L NF R 202
PRK13891
PRK13891 conjugal transfer protein TrbE; Provisional
98-914
1.29e-34
conjugal transfer protein TrbE; Provisional
Pssm-ID: 184375 [Multi-domain]
Cd Length: 852
Bit Score: 142.58
E-value: 1.29e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 98 I SK VD NFM KLK DQS S ---- VEE L IP Y SSHIT D NI IV T KN RDLL A T W QID G AYFECVDS E DLSILTDQL N TLIRSF e G KSV 173
Cdd:PRK13891 24 I RA VD AEL KLK KHR S kdag LAD L LN Y AAVVD D GV IV G KN GSFM A A W LYK G DDNASSTD E QREMVSFRI N QALAGL - G SGW 102
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 174 TLYPHRI R ckkdv RP VF N ------ S KI P - F V NRVMND ---- YY E SF pq SEFF E NKLF LT IC - F K P FTTED K VTHFF ---- 237
Cdd:PRK13891 103 MVHVDAV R ----- RP AP N ysergv S HF P d P V SAAIDE errr LF E GL -- GTMY E GYFV LT LT w F P P VLAQR K FVELM fddd 175
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 238 ---- SRGKKQKDIFKEPVN E MNEICD RL NT -- Y L S R FHSRRLGLYEDHG V VYS D Q LS LF Q YLLS G RWQK V RVS S S P F Y -- 309
Cdd:PRK13891 176 avap DHKARTHGLIEQFKR E ITSLES RL SS av K L T R LRGQKVVNEDGRE V THD D F LS WL Q FCVT G LNHP V MLP S N P M Y ld 255
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 310 TYL GG KD L FF G ndagq ITASDHARYFRCIE I KDYFQ E TDA GIL D AL MY LP V EY VVT S S F TA MD KQS A I K A LD -------- 381
Cdd:PRK13891 256 ALI GG QE L WG G ----- VVPKIGRKFIQVVA I EGFPL E SYP GIL S AL AE LP I EY RWS S R F IF MD QHE A V K H LD kfrkkwkq 330
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 382 ------ DQ I ---------- D K L E M TD DA A k SLL A DLKV GL dm V SS GY isfgks HQTL VV FA D - SP ERL VKDTNI V TSTLE 444
Cdd:PRK13891 331 kirgff DQ V fntntgsidq D A L S M VG DA E - AAI A EVNS GL -- V AQ GY ------ YTSV VV LM D e DR ERL EASALL V EKAIN 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 445 D LG LIVTYS T LSLGA AY FAQ LPG NYTLRP R LSTLSSL N F A EMESFHNFFS G KEKGNT ----- WGEK L ITLRGS G NDIYH L 519
Cdd:PRK13891 402 R LG FAARIE T INTMD AY LGS LPG HGVENV R RPLINTM N L A DLLPTSSIWT G SATAPC pmypp LSPA L MHCVTV G ATPFR L 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 520 N Y H MTT ehqnffgknpt LGHT EIL G TSNV GK TVL L MTK A FAA qqfgtpesfpan R KLKKLTTVF FDK DR ------- AGEV 592
Cdd:PRK13891 482 N L H VRD ----------- LGHT FMF G PTGA GK STH L GII A AQL ------------ R RYAGMSIYA FDK GM smyplaa GIRA 538
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 593 GIRAMG G SYYR V - KEGEPTGWN P AALPP TK RNI A FMKDLVRLLCT LN SEPLDDY Q NSL I SD A VER l M QR S d RSYPI S KLR 671
Cdd:PRK13891 539 ATKGKS G LHFT V a ADDDRLAFC P LQFLE TK GDR A WAMEWIDTILA LN GVNTTPA Q RNE I GN A IMS - M HA S - GARTL S EFS 616
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 672 PL IQ EPDDT E T krhglkar L K PW T QGEEF G WVF D NR ED TFDVDNLD VF G I DGTEF L DN K v L A SAASF YL IY R VTMLAD G R 751
Cdd:PRK13891 617 VT IQ DEAIR E A -------- I K QY T VDGSM G HLL D AE ED GLSLSDFT VF E I EELMN L GE K - F A LPVLL YL FR R IERALK G Q 687
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 752 RLL I YM DE F W QWINNE AFR DFVYNK LK TG RK LDMVLVV ATQS PDELIK S P I AAAVR E QC AT H I Y L A N PK A KRSEYVD --- 828
Cdd:PRK13891 688 PAV I IL DE A W LMLGHP AFR AKIREW LK VL RK ANCLVLM ATQS LSDAAN S G I LDVIV E ST AT K I F L P N VY A RDEDTSA lyr 767
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 829 -- GL QV R EL yf DKIKAID P LSRQFL V VK N PQ R kgesddfaa FAR L E LG KA A yy L PVLS AS KP ------- Q LE L - F DDI W k 898
Cdd:PRK13891 768 rm GL NA R QI -- EILATAI P KRQYYY V SE N GR R --------- LYD L A LG PL A -- L AFVG AS DK esvaaik S LE A k F GHE W - 833
890 900
....*....|....*....|...
gi 485721632 899 egmk PE EWL ------- DT YLE Q A 914
Cdd:PRK13891 834 ---- VH EWL agrglnl ND YLE A A 852
PRK13830
PRK13830 conjugal transfer protein TrbE; Provisional
112-822
9.10e-30
conjugal transfer protein TrbE; Provisional
Pssm-ID: 237525 [Multi-domain]
Cd Length: 818
Bit Score: 126.88
E-value: 9.10e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 112 S VEE L I PY SSHITDNI I VT K NRD L L A T W qidga YF ECV DSE ----- DLSILTD Q L N TLI - R SFE G KSVTL --------- Y 176
Cdd:PRK13830 13 S FAD L V PY AGLVDNGV I LL K DGS L M A G W ----- YF AGP DSE sstda ERNEVSR Q I N AIL s R LGS G WMIQV eavrvptid Y 87
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 177 P HRIR C K kdvrpv F NSK ipf V N R VMNDYYESFPQS E -- F FE NKLF L TICFK P ---------- FTTE D KVTHFF S RGKKQK 244
Cdd:PRK13830 88 P AEDD C H ------ F PDP --- V T R AIDAERRAHFER E sg H FE SRHA L ILTYR P peprrsgltr YIYS D EESRSA S YADTAL 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 245 D I F KEPVN E MNE icdrlnt YL SRFH S - RR LGLY E -- DH G VV ---- Y SDQLSLFQYLLS G RWQK VR VSSS P F Y - TY L GGKD 316
Cdd:PRK13830 159 D S F RTSIR E VEQ ------- YL ANVV S i RR METR E tv ER G GF rvar Y DELFQFIRFCIT G ENHP VR LPDI P M Y l DW L VTAE 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 317 L FF G ndagq I T ASDHA R YFRCIE I KDYFQ E TDA GIL DA L MYL P VE Y VVT S S F TAM D KQS A IKA L DDQ ----------- I D 385
Cdd:PRK13830 232 L QH G ----- L T PKVEN R FLGVVA I DGLPA E SWP GIL NS L DLM P LT Y RWS S R F IFL D AEE A RQK L ERT rkkwqqkvrpf F D 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 386 K L EM T ----- D DA A KSLL A DLKVGLDMV SS GYISF G KSHQTL V V F ADSP ERL VKDTNIVTSTLEDL G LIVTYS TL SLGA A 460
Cdd:PRK13830 307 Q L FQ T qsrsv D QD A MMMV A ETEDAIAQA SS QLVAY G YYTPVI V L F DEDQ ERL QEKAEAIRRLIQAE G FGARIE TL NATD A 386
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 461 YFAQ LPGN YTLRP R LSTLSSL N F A EMESFHNFF SG KEKGNT ---- WGEKLITLRG SG NDIYH LN Y H MTT ehqnffgknpt 536
Cdd:PRK13830 387 FLGS LPGN WYANI R EPLINTR N L A DLIPLNSVW SG SPVAPC pfyp PNSPPLMQVA SG STPFR LN L H VDD ----------- 455
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 537 L GHT E I L G TSNV GK TV LL mtk A FA A Q QF gtpesfpan R KLKKLTTVF FDK D R AGEVGIR A M GG SY Y RVKEGEPTGWNPA A 616
Cdd:PRK13830 456 V GHT L I F G PTGS GK ST LL --- A LI A A QF --------- R RYAGAQIFA FDK G R SMLPLTL A A GG DH Y EIGGDAAEEGEGL A 523
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 617 LP P ----- T KRNI A FMKDLVRL L CT L NSEPLD - D YQ N S l IS DAVERLMQRSD RS yp I S KLRPLI Q EPD dtetkrhg L K AR 690
Cdd:PRK13830 524 FC P laels T DGDR A WAAEWIET L VA L QGVTIT p D HR N A - IS RQIGLMAEARG RS -- L S DFVSGV Q MRE -------- I K DA 592
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 691 L KPW T QGEEF G WVF D NR ED TFDVDNLDV F G I DGTEFLDNKV L ASAAS f YL IY R VTMLAD G RRL LI YM DE F W QWINNEA FR 770
Cdd:PRK13830 593 L HHY T VDGPM G QLL D AE ED GLALGAFQT F E I EELMNMGERN L VPVLT - YL FR R IEKRLT G APS LI IL DE A W LMLGHPV FR 671
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 485721632 771 D FVYNK LK TG RK LDMVL V V ATQS PDELIK S P I AAAVR E Q C A T H I Y L A N PK A K 822
Cdd:PRK13830 672 D KIREW LK VL RK ANCAV V L ATQS ISDAER S G I IDVLK E S C P T K I C L P N GA A R 723
PRK13873
PRK13873 conjugal transfer ATPase TrbE; Provisional
292-821
1.96e-29
conjugal transfer ATPase TrbE; Provisional
Pssm-ID: 237536 [Multi-domain]
Cd Length: 811
Bit Score: 125.79
E-value: 1.96e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 292 YL --- L S G R WQK VRV SSS P F Y -- TY L GGKD L ffgnd A G QITASDHARYF R CIE I KDYFQE T DA GILD A L MY L PVE Y VVTS 366
Cdd:PRK13873 186 YL hst I S T R RHR VRV PET P M Y ld AL L ADQP L ----- T G GLEPRLGDAHL R VLT I RGFPTA T WP GILD D L NR L AFP Y RWST 260
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 367 SFTAM DK QS A I K A L DD ------------- Q I D K LE MT --------- D D A A K SLL AD L --- KV G L D M V SS GY IS fgksh Q T 421
Cdd:PRK13873 261 RAICL DK TD A T K L L TK irrqwfakrksva A I L K EV MT neasalvdt D A A N K AAD AD A alq EL G A D Q V GF GY VT ----- A T 335
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 422 LV V FADS P ERLVKDTNI V TSTLEDL G LIVTYS TL SLGA A YFAQ LPG NYTLRP R LSTL S S LN F A E M ESFHNFFS G K E K g N T 501
Cdd:PRK13873 336 VT V WDAD P AIADEKLRL V EKVIQGR G FTCIPE TL NAVE A WLGS LPG HVYANV R QPPV S T LN L A H M MPLSAVWA G P E R - N E 414
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 502 W -- GEK L ITL R GS G NDIYH L NY H MTT ehqnffgknpt L GHT EIL G TSNV GK T VLL mtk A FA A Q QF gtpesfpan R KLKKL 579
Cdd:PRK13873 415 H ld APP L LYA R TE G STPFR L SL H VGD ----------- V GHT LVV G PTGA GK S VLL --- A LM A L QF --------- R RYPGA 471
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 580 TTVF FD KDRAGEVGIR AMGG SYYRVKE G EPT gwn PA AL P P TK R n I ------ A FMKDLVRLLCTLNS -------- E PLDDY 645
Cdd:PRK13873 472 QVFA FD FGGSIRAATL AMGG DWHDLGG G ADG --- SV AL Q P LA R - I ddeaer A WAAEWIAGILAREG vavtpevk E HIWSA 547
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 646 QN SL I S DA VE rlm Q R S drsyp ISK L RP L I Q E pddtetkr HG LK AR L K P WTQ G EEF G WVF D NREDTFDVDNLDV F GID G te 725
Cdd:PRK13873 548 LT SL A S AP VE --- E R T ----- LTG L SV L L Q S -------- NA LK QA L A P YCL G GPH G RLL D ADAERLGSADVQA F EME G -- 609
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 726 FLDN K VL A S A ASF YL IY R VTMLA DGR RL L IYM DE F W QWINNEA F RDFVYNK LKT G RK LDMVLVV ATQS PDELIK S P IA A A 805
Cdd:PRK13873 610 LMGT K AA A P A VLS YL FH R IEDRF DGR PT L LIL DE A W LFLDDPV F AAQLREW LKT L RK KNVSVIF ATQS LADIDG S A IA P A 689
570
....*....|....*.
gi 485721632 806 VR E Q C A T H I Y L A N PK A 821
Cdd:PRK13873 690 II E S C P T R I F L P N ER A 705
VirB3
COG3702 Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and ...
1-97
3.35e-20
Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442916
Cd Length: 97
Bit Score: 86.09
E-value: 3.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 1 MST LFKGLTRPA LI rg LGVPL Y PF LGMCIICVL L GV W IHE - AMYA L IL P GWYAI R RVTQF D E RFF D LL Y LR TLVKGHSLS 79
Cdd:COG3702 2 EDP LFKGLTRPA MF -- LGVPL V PF VLNVMVSLI L FI W TGS l LYLL L AI P LHFVL R LICRR D P RFF R LL L LR LRTRPRTRN 79
90
....*....|....*...
gi 485721632 80 NKRFSAVH Y AGSQ Y DEVD 97
Cdd:COG3702 80 RRFWGGNS Y SPLP Y RRRR 97
VirB3
pfam05101 Type IV secretory pathway, VirB3-like protein; This family includes the Type IV secretory ...
2-83
6.80e-13
Type IV secretory pathway, VirB3-like protein; This family includes the Type IV secretory pathway VirB3 protein, that is found associated with bacterial inner and outer membranes. The family also includes the conjugal transfer protein TrbD family that contains a nucleotide binding motif and may provide energy for the export of DNA or the export of other Trb proteins.
Pssm-ID: 428303
Cd Length: 82
Bit Score: 64.95
E-value: 6.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 2 ST LFK G LTRPA LI rg LGVPL YP FL GMCIIC V L L G - V WIHEAMYA L IL P GWYAI R RVTQF D E R F F DL L Y L RTLVKGHSL s N 80
Cdd:pfam05101 1 DP LFK A LTRPA MF -- LGVPL EL FL LNGMVS V I L F l V GLSLWYLL L AP P LHLVL R LIAKR D P R M F RV L L L WLQTRPRLR - N 77
...
gi 485721632 81 K RF 83
Cdd:pfam05101 78 R RF 80
HerA
COG0433 Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase ...
539-816
2.48e-08
Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains [Replication, recombination and repair];
Pssm-ID: 440202 [Multi-domain]
Cd Length: 388
Bit Score: 57.31
E-value: 2.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 539 H TE ILG TSNV GK TVL L mtk AFAAQQF gtpesfp ANRKLKK L tt VF fdk D RA GE - V G IRAM G GSYYR V KEGE P TGWN P AAL 617
Cdd:COG0433 49 H IL ILG ATGS GK SNT L --- QVLLEEL ------- SRAGVPV L -- VF --- D PH GE y S G LAEP G AERAD V GVFD P GAGR P LPI 113
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 618 P P tk RNIAF - MKD L VR LL ct L NSEP L D D Y Q NSLISD A VERLMQRSDRSYPISK L RP L IQ E PDDTETK -------- RHG L K 688
Cdd:COG0433 114 N P -- WDLFA t ASE L GP LL -- L SRLD L N D T Q RGVLRE A LRLADDKGLLLLDLKD L IA L LE E GEELGEE ygnvsaas AGA L L 189
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 689 A RL KPWTQGEEF gwv F D nr E DTF D VDN L dv FGI DG ------ TEF L DNKVLASAASFY L -- IYR ----- VTMLADGRR L LI 755
Cdd:COG0433 190 R RL ESLESADGL --- F G -- E PGL D LED L -- LRT DG rvtvid LSG L PEELQSTFVLWL L re LFE arpev GDADDRKLP L VL 262
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 485721632 756 YM DE FWQWINNE -- A FRDFVYNKLKT GRK LDMV L VV ATQ S P DELIKS piaaa V RE Q CA T H I Y L 816
Cdd:COG0433 263 VI DE AHLLAPAA ps A LLEILERIARE GRK FGVG L IL ATQ R P SDIDED ----- V LS Q LG T Q I I L 320
VirD4
COG3505 Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ...
615-817
1.33e-04
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain]
Cd Length: 402
Bit Score: 45.36
E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 615 A ALPPTK R NI A fmk D LV RLL ctln SEP LDDYQNS L isdave RLMQR S DRSYPISK L RPLIQEPDD T ETK - RHG L KAR L KP 693
Cdd:COG3505 115 A LAEEGR R TL A --- D VY RLL ---- SEP EEELREL L ------ EALPE S PHPPVADT L AAFLNAAEK T RSS v LST L ASA L EL 181
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 694 WTQG E EFGWV fdn REDT FD VDN L ----- DVF - GIDGTEFLDNKV L ASAASFY LI YRVTML A DG ----- R RL L IYM DEF wq 762
Cdd:COG3505 182 LSDP E VAALT --- SGSD FD LRD L irekg TLY l VLPPDDLSTLAP L LRLLLSQ LI RALLRR A ER sgrlp R PV L LLL DEF -- 256
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 485721632 763 win NEAF R - DFVYNK L K TGR KLDMV LV VAT QS P --- DELIKSPI A AAVREQ C A T H I Y L A 817
Cdd:COG3505 257 --- ANLG R l PSLETL L A TGR GYGIR LV LIL QS L aql EAIYGEEG A ETILGN C G T K I F L G 312
PRK13854
PRK13854 type IV secretion system protein VirB3; Provisional
2-80
2.62e-03
type IV secretion system protein VirB3; Provisional
Pssm-ID: 139914
Cd Length: 108
Bit Score: 38.27
E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 2 S TL FKGL TRPAL I rg LGVPL YPFLGMCIICVLLG V WIHEAM Y - ALI LP G W YAI R R V TQF D ERFFD -- LL Y LRT lv K G H S L 78
Cdd:PRK13854 8 A TL YLAA TRPAL F -- LGVPL TLAGVFMMLAGFVI V IVQNPL Y e VVL LP L W FGA R L V VER D YNAAS vv LL F LRT -- A G R S V 83
..
gi 485721632 79 SN 80
Cdd:PRK13854 84 DG 85
PRK13899
PRK13899 type IV secretion system protein VirB3; Provisional
4-70
4.69e-03
type IV secretion system protein VirB3; Provisional
Pssm-ID: 237550
Cd Length: 97
Bit Score: 37.43
E-value: 4.69e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 485721632 4 LFKGLTRP AL I rg L GV PL - YPF L G M c II CVLLGV W IHEAMYAL I L - PG WYA I RRVTQ F D E - R F FD L LYLR 70
Cdd:PRK13899 10 LFKGLTRP PM I -- F GV SY k FAA L N M - II SMMVFI W TNDFRILF I A a PG IHG I GYIIC F K E p L F IE L FLNK 76
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
