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Conserved domains on  [gi|486026186|ref|WP_001504034|]
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MULTISPECIES: Rha family transcriptional regulator [Enterobacteriaceae]

Protein Classification

Rha family transcriptional regulator( domain architecture ID 11466542)

Rha family transcriptional regulator is a regulatory protein found in temperate phage and bacterial prophage regions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
14-124 3.59e-39

Phage regulatory protein Rha [Mobilome: prophages, transposons];


:

Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 132.43  E-value: 3.59e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486026186  14 EMVQAKNGEVVTTSRKIAKYFGKRHGDVLRKIEQVKADC-SREFSQRNFASADYIDEQ-GKVRPMYSLTKDGWIMVVMGF 91
Cdd:COG3646    5 ELVTIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLeSPEFGQLNFEESTYEDSQnGRERPEYLLTKDGFTLLVMGF 84

                         90       100       110
                 ....*....|....*....|....*....|...
gi 486026186  92 TGKAAAAIKESYIAAFNWMAEQLSRRMAIGEEM 124
Cdd:COG3646   85 TGKKAAEFKAAYIDRFNEMEEQLKQQSALPQTL 117
 
Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
14-124 3.59e-39

Phage regulatory protein Rha [Mobilome: prophages, transposons];


Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 132.43  E-value: 3.59e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486026186  14 EMVQAKNGEVVTTSRKIAKYFGKRHGDVLRKIEQVKADC-SREFSQRNFASADYIDEQ-GKVRPMYSLTKDGWIMVVMGF 91
Cdd:COG3646    5 ELVTIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLeSPEFGQLNFEESTYEDSQnGRERPEYLLTKDGFTLLVMGF 84

                         90       100       110
                 ....*....|....*....|....*....|...
gi 486026186  92 TGKAAAAIKESYIAAFNWMAEQLSRRMAIGEEM 124
Cdd:COG3646   85 TGKKAAEFKAAYIDRFNEMEEQLKQQSALPQTL 117
Phage_pRha pfam09669
Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in ...
 25-112 1.05e-32

Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.


Pssm-ID: 462849 [Multi-domain]  Cd Length: 91  Bit Score: 111.93  E-value: 1.05e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486026186   25 TTSRKIAKYFGKRHGDVLRKIEQVKAD---CSREFSQRNFASADYIDEQGKVRPMYSLTKDGWIMVVMGFTGKAAAAIKE 101
Cdd:pfam09669   1 TTSLEVAELFGKRHKNVLRDIRKLIKDleeFGEDFRELNFEESPYKDSQGRKRPCYLLTRDGFTLLAMGFTGKKAVEFKA 80

                          90
                  ....*....|.
gi 486026186  102 SYIAAFNWMAE 112
Cdd:pfam09669  81 KYIKAFNEMEE 91
phage_pRha TIGR02681
phage regulatory protein, rha family; Members of this protein family are found in temperate ...
 14-117 3.26e-29

phage regulatory protein, rha family; Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that pRha is a phage regulatory protein. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 131728  Cd Length: 108  Bit Score: 103.74  E-value: 3.26e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486026186   14 EMVQAKNGEVVTTSRKIAKYFGKRHGDVLRKIEQVKADCSR-EFSQRNFASADYIDEQGKVRPMYSLTKDGWIMVVMGFT 92
Cdd:TIGR02681   3 PKVFTKRNQVVTDSLTMAQMFGKRHDNVIRDIKVLLIEANEtEFGQLNFEETQYQDEQNKKQPMFNLTEDGFTIVAMGYT 82

                          90       100
                  ....*....|....*....|....*
gi 486026186   93 GKAAAAIKESYIAAFNWMAEQLSRR 117
Cdd:TIGR02681  83 TPKAMKMKEKFIKEFNEMKEHLQKV 107
 
Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
14-124 3.59e-39

Phage regulatory protein Rha [Mobilome: prophages, transposons];


Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 132.43  E-value: 3.59e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486026186  14 EMVQAKNGEVVTTSRKIAKYFGKRHGDVLRKIEQVKADC-SREFSQRNFASADYIDEQ-GKVRPMYSLTKDGWIMVVMGF 91
Cdd:COG3646    5 ELVTIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLeSPEFGQLNFEESTYEDSQnGRERPEYLLTKDGFTLLVMGF 84

                         90       100       110
                 ....*....|....*....|....*....|...
gi 486026186  92 TGKAAAAIKESYIAAFNWMAEQLSRRMAIGEEM 124
Cdd:COG3646   85 TGKKAAEFKAAYIDRFNEMEEQLKQQSALPQTL 117
Phage_pRha pfam09669
Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in ...
 25-112 1.05e-32

Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.


Pssm-ID: 462849 [Multi-domain]  Cd Length: 91  Bit Score: 111.93  E-value: 1.05e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486026186   25 TTSRKIAKYFGKRHGDVLRKIEQVKAD---CSREFSQRNFASADYIDEQGKVRPMYSLTKDGWIMVVMGFTGKAAAAIKE 101
Cdd:pfam09669   1 TTSLEVAELFGKRHKNVLRDIRKLIKDleeFGEDFRELNFEESPYKDSQGRKRPCYLLTRDGFTLLAMGFTGKKAVEFKA 80

                          90
                  ....*....|.
gi 486026186  102 SYIAAFNWMAE 112
Cdd:pfam09669  81 KYIKAFNEMEE 91
phage_pRha TIGR02681
phage regulatory protein, rha family; Members of this protein family are found in temperate ...
 14-117 3.26e-29

phage regulatory protein, rha family; Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that pRha is a phage regulatory protein. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 131728  Cd Length: 108  Bit Score: 103.74  E-value: 3.26e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 486026186   14 EMVQAKNGEVVTTSRKIAKYFGKRHGDVLRKIEQVKADCSR-EFSQRNFASADYIDEQGKVRPMYSLTKDGWIMVVMGFT 92
Cdd:TIGR02681   3 PKVFTKRNQVVTDSLTMAQMFGKRHDNVIRDIKVLLIEANEtEFGQLNFEETQYQDEQNKKQPMFNLTEDGFTIVAMGYT 82

                          90       100
                  ....*....|....*....|....*
gi 486026186   93 GKAAAAIKESYIAAFNWMAEQLSRR 117
Cdd:TIGR02681  83 TPKAMKMKEKFIKEFNEMKEHLQKV 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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