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Conserved domains on  [gi|487749130|ref|WP_001831121|]
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MULTISPECIES: bacillithiol disulfide reductase YpdA [Staphylococcus]

Protein Classification

YpdA family putative bacillithiol disulfide reductase( domain architecture ID 11499296)

YpdA family putative bacillithiol disulfide reductase may function as a thiol disulfide oxidoreductase and is present only in species with an active bacillithiol system

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bthiol_YpdA TIGR04018
putative bacillithiol system oxidoreductase, YpdA family; Members of this protein family, ...
 5-321 0e+00

putative bacillithiol system oxidoreductase, YpdA family; Members of this protein family, including YpdA from Bacillus subtilis, are apparent oxidoreductases present only in species with an active bacillithiol system. They have been suggested actually to be thiol disulfide oxidoreductases (TDOR), although the evidence is incomplete. [Unknown function, Enzymes of unknown specificity]


:

Pssm-ID: 188533 [Multi-domain]  Cd Length: 316  Bit Score: 509.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130    5 ESIIIGGGPCGLSAAIEQKKKGIETLVIEKGNVVESIYNYPTHQTFFSSSDKLSIGDIPFIVEDSKPRRNQALVYYREVV 84
Cdd:TIGR04018   1 DVIIIGAGPCGLACAIEAQKAGLSYLIIEKGNLVNSIYRYPTNMTFFSTSERLEIGGIPFISENPKPTRNEALEYYRRVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   85 KHHQLNIHPFEEVLTVKKINNKFAITTTKGVYECKYLTVATGYYGQHNTLEAEGAELPKVFHYFKEAHPYFNQNVVIIGG 164
Cdd:TIGR04018  81 ERFKLNIRLYEEVLKVKKTDGGFEVTTEKGTYQAKNVIVATGYYDIPNLLNVPGEDLPKVSHYYKEAHPYFGQKVVVVGG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  165 KNSAVDAALELEKAGANVTVLYRGEQYPKAIKPWILPNFESLVNHEKITMEFNATVTKITDHSVTYEK-DGQLIEIDNDY 243
Cdd:TIGR04018 161 SNSAVDAALELYRKGAEVTMVHRGDEVSSSVKYWVRPDIENRIKEGSIKAYFNSRVKEITEDSVTLETpDGEVHTIPNDF 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 487749130  244 VFAMIGYHPDYDFLKTIGIDIhtNEYGTAPVYNRETFETNVENCYIAGVIAAGNDANTIFIENGKYHGGVITQSILTK 321
Cdd:TIGR04018 241 VFALTGYRPDFEFLESLGVEL--DEDTGIPVYNPETMETNVPGLYLAGVIAAGMDTNKIFIENGRFHAPLIAEHIASK 316
 
Name Accession Description Interval E-value
Bthiol_YpdA TIGR04018
putative bacillithiol system oxidoreductase, YpdA family; Members of this protein family, ...
 5-321 0e+00

putative bacillithiol system oxidoreductase, YpdA family; Members of this protein family, including YpdA from Bacillus subtilis, are apparent oxidoreductases present only in species with an active bacillithiol system. They have been suggested actually to be thiol disulfide oxidoreductases (TDOR), although the evidence is incomplete. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 188533 [Multi-domain]  Cd Length: 316  Bit Score: 509.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130    5 ESIIIGGGPCGLSAAIEQKKKGIETLVIEKGNVVESIYNYPTHQTFFSSSDKLSIGDIPFIVEDSKPRRNQALVYYREVV 84
Cdd:TIGR04018   1 DVIIIGAGPCGLACAIEAQKAGLSYLIIEKGNLVNSIYRYPTNMTFFSTSERLEIGGIPFISENPKPTRNEALEYYRRVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   85 KHHQLNIHPFEEVLTVKKINNKFAITTTKGVYECKYLTVATGYYGQHNTLEAEGAELPKVFHYFKEAHPYFNQNVVIIGG 164
Cdd:TIGR04018  81 ERFKLNIRLYEEVLKVKKTDGGFEVTTEKGTYQAKNVIVATGYYDIPNLLNVPGEDLPKVSHYYKEAHPYFGQKVVVVGG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  165 KNSAVDAALELEKAGANVTVLYRGEQYPKAIKPWILPNFESLVNHEKITMEFNATVTKITDHSVTYEK-DGQLIEIDNDY 243
Cdd:TIGR04018 161 SNSAVDAALELYRKGAEVTMVHRGDEVSSSVKYWVRPDIENRIKEGSIKAYFNSRVKEITEDSVTLETpDGEVHTIPNDF 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 487749130  244 VFAMIGYHPDYDFLKTIGIDIhtNEYGTAPVYNRETFETNVENCYIAGVIAAGNDANTIFIENGKYHGGVITQSILTK 321
Cdd:TIGR04018 241 VFALTGYRPDFEFLESLGVEL--DEDTGIPVYNPETMETNVPGLYLAGVIAAGMDTNKIFIENGRFHAPLIAEHIASK 316
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
13-291 3.52e-122

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 352.68  E-value: 3.52e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   13 PCGLSAAIEQKKKGIET-LVIEKGNVVESIYNYPTHQTFFSSSD---KLSIGDIPFIVEDSKP---------RRNQALVY 79
Cdd:pfam13738   1 PAGIGCAIALKKAGLEDyLILEKGNIGNSFYRYPTHMTFFSPSFtsnGFGIPDLNAISPGTSPaftfnrehpSGNEYAEY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   80 YREVVKHHQLNIHPFEEVLTVKKINNKFAITTTKGVYECKYLTVATGYYGQHNTLEAEgaELPKVFHYFKEAHPYFNQNV 159
Cdd:pfam13738  81 LRRVADHFELPINLFEEVTSVKKEDDGFVVTTSKGTYQARYVIIATGEFDFPNKLGVP--ELPKHYSYVKDFHPYAGQKV 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  160 VIIGGKNSAVDAALELEKAGANVTVLYRGEQ-------YPKAIKPWILPNFESLVNHEKITMEFNATVTKITDHSVTYE- 231
Cdd:pfam13738 159 VVIGGYNSAVDAALELVRKGARVTVLYRGSEwedrdsdPSYSLSPDTLNRLEELVKNGKIKAHFNAEVKEITEVDVSYKv 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487749130  232 --KDGQLIEIDNDYVFAmIGYHPDYDFLKTIGIDIHTNEYgtaPVYNRETFETNVENCYIAG 291
Cdd:pfam13738 239 htEDGRKVTSNDDPILA-TGYHPDLSFLKKGLFELDEDGR---PVLTEETESTNVPGLFLAG 296
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
7-297 5.36e-44

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 152.97  E-value: 5.36e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNV------VESIYNYPthqtffsssdklsiGDIPFIvedskprRNQALV-Y 79
Cdd:COG0492    4 VIIGAGPAGLTAAIYAARAGLKTLVIEGGEPggqlatTKEIENYP--------------GFPEGI-------SGPELAeR 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  80 YREVVKHHQLNIHpFEEVLTVKKINNKFAITTTKG-VYECKYLTVATGyyGQHNTLEAEGAELPKVF--HYFKEAHPYF- 155
Cdd:COG0492   63 LREQAERFGAEIL-LEEVTSVDKDDGPFRVTTDDGtEYEAKAVIIATG--AGPRKLGLPGEEEFEGRgvSYCATCDGFFf 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 156 -NQNVVIIGGKNSAVDAALELEKAGANVTVLYRGEQyPKAIKPWIlpnfESLVNHEKITMEFNATVTKITD----HSVTY 230
Cdd:COG0492  140 rGKDVVVVGGGDSALEEALYLTKFASKVTLIHRRDE-LRASKILV----ERLRANPKIEVLWNTEVTEIEGdgrvEGVTL 214

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 487749130 231 E--KDGQLIEIDNDYVFAMIGYHPDYDFLKTIGIDIhtNEYGTAPVynRETFETNVEncyiaGVIAAGN 297
Cdd:COG0492  215 KnvKTGEEKELEVDGVFVAIGLKPNTELLKGLGLEL--DEDGYIVV--DEDMETSVP-----GVFAAGD 274
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 1-300 1.64e-13

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 70.98  E-value: 1.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   1 MQTIESIIIGGGPCGLSAAIEQKKKGIETLVIEKGN---------------VVES--IYNYPTH-QTFFSSSDKLSIgDI 62
Cdd:PRK06292   1 MEKYDVIVIGAGPAGYVAARRAAKLGKKVALIEKGPlggtclnvgcipskaLIAAaeAFHEAKHaEEFGIHADGPKI-DF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  63 PFIVEDSKPRRNqalvyyrEVVKHHQLNIhpfEEVLTVKKI--------NNKFAITTTKgvYECKYLTVATGyygqhntl 134
Cdd:PRK06292  80 KKVMARVRRERD-------RFVGGVVEGL---EKKPKIDKIkgtarfvdPNTVEVNGER--IEAKNIVIATG-------- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 135 eAEGAELPKVFhYFKEAHPYFN----------QNVVIIGGknSAVdaALELEKA----GANVTVLYRGEQypkaikpwIL 200
Cdd:PRK06292 140 -SRVPPIPGVW-LILGDRLLTSddafeldklpKSLAVIGG--GVI--GLELGQAlsrlGVKVTVFERGDR--------IL 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 201 PNFESLVNH-------EKITMEFNATVTKITDHS----VTYEKDGQLIEIDNDYVFAMIGYHPDYDFLKTIGIDIHTNEY 269
Cdd:PRK06292 206 PLEDPEVSKqaqkilsKEFKIKLGAKVTSVEKSGdekvEELEKGGKTETIEADYVLVATGRRPNTDGLGLENTGIELDER 285

                        330       340       350
                 ....*....|....*....|....*....|.
gi 487749130 270 GTaPVYNrETFETNVENCYIAGviaagnDAN 300
Cdd:PRK06292 286 GR-PVVD-EHTQTSVPGIYAAG------DVN 308
 
Name Accession Description Interval E-value
Bthiol_YpdA TIGR04018
putative bacillithiol system oxidoreductase, YpdA family; Members of this protein family, ...
 5-321 0e+00

putative bacillithiol system oxidoreductase, YpdA family; Members of this protein family, including YpdA from Bacillus subtilis, are apparent oxidoreductases present only in species with an active bacillithiol system. They have been suggested actually to be thiol disulfide oxidoreductases (TDOR), although the evidence is incomplete. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 188533 [Multi-domain]  Cd Length: 316  Bit Score: 509.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130    5 ESIIIGGGPCGLSAAIEQKKKGIETLVIEKGNVVESIYNYPTHQTFFSSSDKLSIGDIPFIVEDSKPRRNQALVYYREVV 84
Cdd:TIGR04018   1 DVIIIGAGPCGLACAIEAQKAGLSYLIIEKGNLVNSIYRYPTNMTFFSTSERLEIGGIPFISENPKPTRNEALEYYRRVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   85 KHHQLNIHPFEEVLTVKKINNKFAITTTKGVYECKYLTVATGYYGQHNTLEAEGAELPKVFHYFKEAHPYFNQNVVIIGG 164
Cdd:TIGR04018  81 ERFKLNIRLYEEVLKVKKTDGGFEVTTEKGTYQAKNVIVATGYYDIPNLLNVPGEDLPKVSHYYKEAHPYFGQKVVVVGG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  165 KNSAVDAALELEKAGANVTVLYRGEQYPKAIKPWILPNFESLVNHEKITMEFNATVTKITDHSVTYEK-DGQLIEIDNDY 243
Cdd:TIGR04018 161 SNSAVDAALELYRKGAEVTMVHRGDEVSSSVKYWVRPDIENRIKEGSIKAYFNSRVKEITEDSVTLETpDGEVHTIPNDF 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 487749130  244 VFAMIGYHPDYDFLKTIGIDIhtNEYGTAPVYNRETFETNVENCYIAGVIAAGNDANTIFIENGKYHGGVITQSILTK 321
Cdd:TIGR04018 241 VFALTGYRPDFEFLESLGVEL--DEDTGIPVYNPETMETNVPGLYLAGVIAAGMDTNKIFIENGRFHAPLIAEHIASK 316
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
13-291 3.52e-122

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 352.68  E-value: 3.52e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   13 PCGLSAAIEQKKKGIET-LVIEKGNVVESIYNYPTHQTFFSSSD---KLSIGDIPFIVEDSKP---------RRNQALVY 79
Cdd:pfam13738   1 PAGIGCAIALKKAGLEDyLILEKGNIGNSFYRYPTHMTFFSPSFtsnGFGIPDLNAISPGTSPaftfnrehpSGNEYAEY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   80 YREVVKHHQLNIHPFEEVLTVKKINNKFAITTTKGVYECKYLTVATGYYGQHNTLEAEgaELPKVFHYFKEAHPYFNQNV 159
Cdd:pfam13738  81 LRRVADHFELPINLFEEVTSVKKEDDGFVVTTSKGTYQARYVIIATGEFDFPNKLGVP--ELPKHYSYVKDFHPYAGQKV 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  160 VIIGGKNSAVDAALELEKAGANVTVLYRGEQ-------YPKAIKPWILPNFESLVNHEKITMEFNATVTKITDHSVTYE- 231
Cdd:pfam13738 159 VVIGGYNSAVDAALELVRKGARVTVLYRGSEwedrdsdPSYSLSPDTLNRLEELVKNGKIKAHFNAEVKEITEVDVSYKv 238

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487749130  232 --KDGQLIEIDNDYVFAmIGYHPDYDFLKTIGIDIHTNEYgtaPVYNRETFETNVENCYIAG 291
Cdd:pfam13738 239 htEDGRKVTSNDDPILA-TGYHPDLSFLKKGLFELDEDGR---PVLTEETESTNVPGLFLAG 296
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
7-297 5.36e-44

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 152.97  E-value: 5.36e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNV------VESIYNYPthqtffsssdklsiGDIPFIvedskprRNQALV-Y 79
Cdd:COG0492    4 VIIGAGPAGLTAAIYAARAGLKTLVIEGGEPggqlatTKEIENYP--------------GFPEGI-------SGPELAeR 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  80 YREVVKHHQLNIHpFEEVLTVKKINNKFAITTTKG-VYECKYLTVATGyyGQHNTLEAEGAELPKVF--HYFKEAHPYF- 155
Cdd:COG0492   63 LREQAERFGAEIL-LEEVTSVDKDDGPFRVTTDDGtEYEAKAVIIATG--AGPRKLGLPGEEEFEGRgvSYCATCDGFFf 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 156 -NQNVVIIGGKNSAVDAALELEKAGANVTVLYRGEQyPKAIKPWIlpnfESLVNHEKITMEFNATVTKITD----HSVTY 230
Cdd:COG0492  140 rGKDVVVVGGGDSALEEALYLTKFASKVTLIHRRDE-LRASKILV----ERLRANPKIEVLWNTEVTEIEGdgrvEGVTL 214

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 487749130 231 E--KDGQLIEIDNDYVFAMIGYHPDYDFLKTIGIDIhtNEYGTAPVynRETFETNVEncyiaGVIAAGN 297
Cdd:COG0492  215 KnvKTGEEKELEVDGVFVAIGLKPNTELLKGLGLEL--DEDGYIVV--DEDMETSVP-----GVFAAGD 274
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 7-291 1.03e-24

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 101.24  E-value: 1.03e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130    7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNvvesiyNYPTHQTFFSSsdklSIGDIPFIVEDSKpRRNQALVYYREVVKH 86
Cdd:pfam07992   4 VVIGGGPAGLAAALTLAQLGGKVTLIEDEG------TCPYGGCVLSK----ALLGAAEAPEIAS-LWADLYKRKEEVVKK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   87 HQLNIHPF--EEVLTVKKINNKFAITTTKGV----YECKYLTVATGyyGQHNTLEAEGAELPKVFH--YFKEAHPYFN-- 156
Cdd:pfam07992  73 LNNGIEVLlgTEVVSIDPGAKKVVLEELVDGdgetITYDRLVIATG--ARPRLPPIPGVELNVGFLvrTLDSAEALRLkl 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  157 --QNVVIIGGKNSAVDAALELEKAGANVTVLYRGE----QYPKAIKPWILPNFEslvnHEKITMEFNATVTKITDHSVTY 230
Cdd:pfam07992 151 lpKRVVVVGGGYIGVELAAALAKLGKEVTLIEALDrllrAFDEEISAALEKALE----KNGVEVRLGTSVKEIIGDGDGV 226

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 487749130  231 E---KDGQliEIDNDYVFAMIGYHPDYDFLKTIGIDihTNEYGTAPVynRETFETNVENCYIAG 291
Cdd:pfam07992 227 EvilKDGT--EIDADLVVVAIGRRPNTELLEAAGLE--LDERGGIVV--DEYLRTSVPGIYAAG 284
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-291 2.26e-21

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 93.77  E-value: 2.26e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   1 MQTIESIIIGGGPCGLSAAIEQKKKGIETLVIEKGNVVE---SIYNYPThQTFFSSSDKLSIGDIPFIVEDSK-PRRNQA 76
Cdd:COG2072    4 TEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGgtwRDNRYPG-LRLDTPSHLYSLPFFPNWSDDPDfPTGDEI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  77 LVYYREVVKHHQLNIHPFE--EVLTV--KKINNKFAITTTKG-VYECKYLTVATGYYGQHNTLEAEGAELPK--VFH--Y 147
Cdd:COG2072   83 LAYLEAYADKFGLRRPIRFgtEVTSArwDEADGRWTVTTDDGeTLTARFVVVATGPLSRPKIPDIPGLEDFAgeQLHsaD 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 148 FKEAHPYFNQNVVIIGGKNSAVDAALELEKAGANVTVLYRGEQY--------PKAIKPWILPNFES-------------- 205
Cdd:COG2072  163 WRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWvlprpnydPERGRPANYLGLEAppalnrrdarawlr 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 206 ----------------------------------LVNHEKITMEfNATVTKITDHSVTYEkDGQLIEIDNdYVFAmIGYH 251
Cdd:COG2072  243 rllraqvkdpelglltpdyppgckrpllstdyyeALRRGNVELV-TGGIERITEDGVVFA-DGTEHEVDV-IVWA-TGFR 318

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 487749130 252 PDYDFLKTIGIdihTNEYG-TAPVYNRETFETNVENCYIAG 291
Cdd:COG2072  319 ADLPWLAPLDV---RGRDGrSGPRAYLGVVVPGFPNLFFLG 356
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 62-291 3.65e-14

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 72.15  E-value: 3.65e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  62 IPFIVEDSKPRRNQALVYYREVVKHHQLNIHPFEEVLtvkKIN--NKFAITTTKGVYECKYLTVATGyyGQHNTLEAEGA 139
Cdd:COG0446   24 LPYYVGGGIKDPEDLLVRTPESFERKGIDVRTGTEVT---AIDpeAKTVTLRDGETLSYDKLVLATG--ARPRPPPIPGL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 140 ELPKVFH------------YFKEAHPyfnQNVVIIGGKNSAVDAALELEKAGANVTVLYRGEQYPKAIKPWILPNFESLV 207
Cdd:COG0446   99 DLPGVFTlrtlddadalreALKEFKG---KRAVVIGGGPIGLELAEALRKRGLKVTLVERAPRLLGVLDPEMAALLEEEL 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 208 NHEKITMEFNATVTKI--TDHSVTYEKDGQliEIDNDYVFAMIGYHPDYDFLKTIGIDIHTNeyGTAPVyNrETFETNVE 285
Cdd:COG0446  176 REHGVELRLGETVVAIdgDDKVAVTLTDGE--EIPADLVVVAPGVRPNTELAKDAGLALGER--GWIKV-D-ETLQTSDP 249


                 ....*.
gi 487749130 286 NCYIAG 291
Cdd:COG0446  250 DVYAAG 255
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 1-300 1.64e-13

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 70.98  E-value: 1.64e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   1 MQTIESIIIGGGPCGLSAAIEQKKKGIETLVIEKGN---------------VVES--IYNYPTH-QTFFSSSDKLSIgDI 62
Cdd:PRK06292   1 MEKYDVIVIGAGPAGYVAARRAAKLGKKVALIEKGPlggtclnvgcipskaLIAAaeAFHEAKHaEEFGIHADGPKI-DF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  63 PFIVEDSKPRRNqalvyyrEVVKHHQLNIhpfEEVLTVKKI--------NNKFAITTTKgvYECKYLTVATGyygqhntl 134
Cdd:PRK06292  80 KKVMARVRRERD-------RFVGGVVEGL---EKKPKIDKIkgtarfvdPNTVEVNGER--IEAKNIVIATG-------- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 135 eAEGAELPKVFhYFKEAHPYFN----------QNVVIIGGknSAVdaALELEKA----GANVTVLYRGEQypkaikpwIL 200
Cdd:PRK06292 140 -SRVPPIPGVW-LILGDRLLTSddafeldklpKSLAVIGG--GVI--GLELGQAlsrlGVKVTVFERGDR--------IL 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 201 PNFESLVNH-------EKITMEFNATVTKITDHS----VTYEKDGQLIEIDNDYVFAMIGYHPDYDFLKTIGIDIHTNEY 269
Cdd:PRK06292 206 PLEDPEVSKqaqkilsKEFKIKLGAKVTSVEKSGdekvEELEKGGKTETIEADYVLVATGRRPNTDGLGLENTGIELDER 285

                        330       340       350
                 ....*....|....*....|....*....|.
gi 487749130 270 GTaPVYNrETFETNVENCYIAGviaagnDAN 300
Cdd:PRK06292 286 GR-PVVD-EHTQTSVPGIYAAG------DVN 308
TIGR00275 TIGR00275
flavoprotein, HI0933 family; The model when searched with a partial length search brings in ...
 7-126 1.08e-11

flavoprotein, HI0933 family; The model when searched with a partial length search brings in proteins with a dinucleotide-binding motif (Rossman fold) over the initial 40 residues of the model, including oxidoreductases and dehydrogenases. Partially characterized members include an FAD-binding protein from Bacillus cereus and flavoprotein HI0933 from Haemophilus influenzae. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 272992 [Multi-domain]  Cd Length: 400  Bit Score: 64.92  E-value: 1.08e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130    7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNVV---------------------ESIYNYPTHQTF-------FSSSDKL- 57
Cdd:TIGR00275   1 IIIGGGAAGLMAAITAARAGLSVLLLEKNKKIgkkllisgggrcnltnscptpEFVAYYPRNGKFlrsalsrFSNKDLId 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   58 ---SIGdIPFIVEDSK---PRRNQAlvyyREVV-------KHHQLNIHPFEEVLTVKKINNKFAITTTKGVYECKYLTVA 124
Cdd:TIGR00275  81 ffeSLG-LELKVEEDGrvfPCSDSA----ADVLdallnelKELGVEILTNSKVKSIEKEDGGFGVETSGGEYEADKVIIA 155


                  ..
gi 487749130  125 TG 126
Cdd:TIGR00275 156 TG 157
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 7-291 2.71e-10

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 60.87  E-value: 2.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEKG-------NVvesiynypthqtffsssdklsiGDIPfivedSKprrnqALVY 79
Cdd:COG1249    7 VVIGAGPGGYVAAIRAAQLGLKVALVEKGrlggtclNV----------------------GCIP-----SK-----ALLH 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  80 ----YREVVKHHQLNIHP------FEEVL-----TVKKINNKFA-------ITTTKG----------------VYECKYL 121
Cdd:COG1249   55 aaevAHEARHAAEFGISAgapsvdWAALMarkdkVVDRLRGGVEellkkngVDVIRGrarfvdphtvevtggeTLTADHI 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 122 TVATGyyGQHNTLEAEGAELPKVFHYfKEAhpyFN-----QNVVIIGGknSAVdaALEL----EKAGANVTVLYRGEQyp 192
Cdd:COG1249  135 VIATG--SRPRVPPIPGLDEVRVLTS-DEA---LEleelpKSLVVIGG--GYI--GLEFaqifARLGSEVTLVERGDR-- 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 193 kaikpwILPNFESLV--------NHEKITMEFNATVTKITDHS----VTYEKDGQLIEIDNDYVFAMIGYHPDydfLKTI 260
Cdd:COG1249  203 ------LLPGEDPEIsealekalEKEGIDILTGAKVTSVEKTGdgvtVTLEDGGGEEAVEADKVLVATGRRPN---TDGL 273

                        330       340       350
                 ....*....|....*....|....*....|....
gi 487749130 261 GID---IHTNEYGTAPVyNrETFETNVENCYIAG 291
Cdd:COG1249  274 GLEaagVELDERGGIKV-D-EYLRTSVPGIYAIG 305
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 123-291 1.76e-09

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 58.61  E-value: 1.76e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 123 VATGYyGQHNTLEAEGAELPKVF-----------HYFKEAHPYFNQNVVIIGGKNSAVDAALELEKAGA-NVTVLYR-GE 189
Cdd:COG0493  212 LATGA-GKPRDLGIPGEDLKGVHsamdfltavnlGEAPDTILAVGKRVVVIGGGNTAMDCARTALRLGAeSVTIVYRrTR 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 190 QYPKAIKpwilpnFEslVNH---EKITMEFNATVTKITDH------SVTYEK-----------------DGQLIEIDNDY 243
Cdd:COG0493  291 EEMPASK------EE--VEEaleEGVEFLFLVAPVEIIGDengrvtGLECVRmelgepdesgrrrpvpiEGSEFTLPADL 362

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 487749130 244 VFAMIGYHPDYDFLKTIgIDIHTNEYGTAPVyNRETFETNVENCYIAG 291
Cdd:COG0493  363 VILAIGQTPDPSGLEEE-LGLELDKRGTIVV-DEETYQTSLPGVFAGG 408
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 123-298 1.55e-08

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 55.57  E-value: 1.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 123 VATGYYGQhNTLEAEGAELPKVFH---YFKE---AHPYFN----QNVVIIGGKNSAVDAALELEKAGA-NVTVLYR--GE 189
Cdd:PRK11749 231 IGTGAGLP-RFLGIPGENLGGVYSavdFLTRvnqAVADYDlpvgKRVVVIGGGNTAMDAARTAKRLGAeSVTIVYRrgRE 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 190 QYPKAIkpwilpnFEslVNH---EKITMEFNATVTKITD-----HSVTYEK----------------DGQLIEIDNDYVF 245
Cdd:PRK11749 310 EMPASE-------EE--VEHakeEGVEFEWLAAPVEILGdegrvTGVEFVRmelgepdasgrrrvpiEGSEFTLPADLVI 380

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 487749130 246 AMIGYHPDYDFLKTIGiDIHTNEYGTaPVYNRETFETNVENCYIAGVIAAGND 298
Cdd:PRK11749 381 KAIGQTPNPLILSTTP-GLELNRWGT-IIADDETGRTSLPGVFAGGDIVTGAA 431
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 7-291 2.20e-07

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 51.96  E-value: 2.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   7 IIIGGGPCGLSAAIEQKK--KGIETLVIEKGNVVesiynypthqtffsssdklSIG--DIPFIVEDSKPRRNQALVYYRE 82
Cdd:PRK09564   4 IIIGGTAAGMSAAAKAKRlnKELEITVYEKTDIV-------------------SFGacGLPYFVGGFFDDPNTMIARTPE 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  83 VVKHHQLNIHPFEEVLTVKKINNKFAI--TTTKGVYECKY--LTVATG---------------YYGQHNTleAEGAELPK 143
Cdd:PRK09564  65 EFIKSGIDVKTEHEVVKVDAKNKTITVknLKTGSIFNDTYdkLMIATGarpiippikninlenVYTLKSM--EDGLALKE 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 144 VFHyfKEAhpyfNQNVVIIGGKNSAVDAALELEKAGANVTVLYRGEQ-YPKAIKPWILPNFESLVNHEKITMEFNATVTk 222
Cdd:PRK09564 143 LLK--DEE----IKNIVIIGAGFIGLEAVEAAKHLGKNVRIIQLEDRiLPDSFDKEITDVMEEELRENGVELHLNEFVK- 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 223 itdhSVTYEKDGQLI-----EIDNDYVFAMIGYHPDYDFLKTIGID------IHTNEYGtapvynretfETNVENCYIAG 291
Cdd:PRK09564 216 ----SLIGEDKVEGVvtdkgEYEADVVIVATGVKPNTEFLEDTGLKtlkngaIIVDEYG----------ETSIENIYAAG 281
PRK10262 PRK10262
thioredoxin reductase; Provisional
 7-191 6.65e-07

thioredoxin reductase; Provisional


Pssm-ID: 182343 [Multi-domain]  Cd Length: 321  Bit Score: 50.06  E-value: 6.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVI---EKG---NVVESIYNYPTHQTFFSSsdklsigdiPFIVEDskpRRNQALVYY 80
Cdd:PRK10262  10 LILGSGPAGYTAAVYAARANLQPVLItgmEKGgqlTTTTEVENWPGDPNDLTG---------PLLMER---MHEHATKFE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  81 REVVkhhqlnihpFEEVLTVKKINNKFAITTTKGVYECKYLTVATGYYGQHNTLEAEGAELPKVFHYFKEAHPYF--NQN 158
Cdd:PRK10262  78 TEII---------FDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFyrNQK 148

                        170       180       190
                 ....*....|....*....|....*....|...
gi 487749130 159 VVIIGGKNSAVDAALELEKAGANVTVLYRGEQY 191
Cdd:PRK10262 149 VAVIGGGNTAVEEALYLSNIASEVHLIHRRDGF 181
HI0933_like pfam03486
HI0933-like protein;
7-126 1.07e-06

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 49.89  E-value: 1.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130    7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNVV----------------------ESIYNYPTHQTFFSSSdkLSIGD--- 61
Cdd:pfam03486   4 IVIGGGAAGLMAAISAAKRGRRVLLIEKGKKLgrkilisgggrcnvtnlseepdNFLSRYPGNPKFLKSA--LSRFTpwd 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   62 ---------IPFIVEDSK---PRRNQAlvyyREVVK--HHQLN-----IHPFEEVLTVKKINNK-FAITTTKGVYECKYL 121
Cdd:pfam03486  82 fiaffeslgVPLKEEDHGrlfPDSDKA----SDIVDalLNELKelgvkIRLRTRVLSVEKDDDGrFRVKTGGEELEADSL 157


                  ....*
gi 487749130  122 TVATG 126
Cdd:pfam03486 158 VLATG 162
PRK13512 PRK13512
coenzyme A disulfide reductase; Provisional
 65-294 1.63e-06

coenzyme A disulfide reductase; Provisional


Pssm-ID: 184103 [Multi-domain]  Cd Length: 438  Bit Score: 49.40  E-value: 1.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  65 IVEDskprRNQALVYYREVVKHH-QLNIHPFEEVLTVKKINNKFAITT--TKGVYECKYLTVATGYYGQHNTLeaeGAEL 141
Cdd:PRK13512  52 VVED----RKYALAYTPEKFYDRkQITVKTYHEVIAINDERQTVTVLNrkTNEQFEESYDKLILSPGASANSL---GFES 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 142 PKVF------------HYFKEAHPyfnQNVVIIGGKNSAVDAALELEKAGANVTVLYRGEQYPKAIKPWILPNFESLVNH 209
Cdd:PRK13512 125 DITFtlrnledtdaidQFIKANQV---DKALVVGAGYISLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDK 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 210 EKITMEFNATVTKITDHSVTYeKDGqlIEIDNDYVFAMIGYHPDYDFLKTIGIDIhtNEYGTAPVynRETFETNVENCYI 289
Cdd:PRK13512 202 REIPYRLNEEIDAINGNEVTF-KSG--KVEHYDMIIEGVGTHPNSKFIESSNIKL--DDKGFIPV--NDKFETNVPNIYA 274


                 ....*
gi 487749130 290 AGVIA 294
Cdd:PRK13512 275 IGDII 279
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
7-295 2.49e-06

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 48.59  E-value: 2.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   7 IIIGGGPCGLSAAIE---QKKKGIETLVIEKGNvvesiynyptHQTFfsssdklsIGDIPFIVEDSKPRRNQAlVYYREV 83
Cdd:COG1252    5 VIVGGGFAGLEAARRlrkKLGGDAEVTLIDPNP----------YHLF--------QPLLPEVAAGTLSPDDIA-IPLREL 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  84 VKHHQLNIHPfEEVLTVKKINNKfaITTTKGV---YEckYLTVATGyyGQHNTLEAEGAE---LP------------KVF 145
Cdd:COG1252   66 LRRAGVRFIQ-GEVTGIDPEART--VTLADGRtlsYD--YLVIATG--SVTNFFGIPGLAehaLPlktledalalreRLL 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 146 HYFKEAHPYFNQNVVIIGGKNSAVDAALELEKAgANVTVLYRGEQyPKAIK-------PWILPNF-ESLVNH-----EK- 211
Cdd:COG1252  139 AAFERAERRRLLTIVVVGGGPTGVELAGELAEL-LRKLLRYPGID-PDKVRitlveagPRILPGLgEKLSEAaekelEKr 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 212 -ITMEFNATVTKITDHSVTYEkDGQliEIDNDYVFAMIGYHPDyDFLKTIGIDihTNEYGTAPVynRETFET-NVENCYI 289
Cdd:COG1252  217 gVEVHTGTRVTEVDADGVTLE-DGE--EIPADTVIWAAGVKAP-PLLADLGLP--TDRRGRVLV--DPTLQVpGHPNVFA 288


                 ....*.
gi 487749130 290 AGVIAA 295
Cdd:COG1252  289 IGDCAA 294
PRK06126 PRK06126
hypothetical protein; Provisional
 1-98 1.54e-05

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 46.52  E-value: 1.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   1 MQTIES--IIIGGGPCGLSAAIEQKKKGIETLVIE---------KGN--------------VVESIY------NYPTHQT 49
Cdd:PRK06126   3 ENTSETpvLIVGGGPVGLALALDLGRRGVDSILVErkdgtafnpKANttsarsmehfrrlgIADEVRsaglpvDYPTDIA 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 487749130  50 FFSSSDKLSIG--DIPFIVEDSKPRRNQAlVYYREVVKHHQLNIHPFEEVL 98
Cdd:PRK06126  83 YFTRLTGYELArfRLPSAREAITPVGGPD-GSWPSPELPHRIPQKYLEPIL 132
PRK15317 PRK15317
alkyl hydroperoxide reductase subunit F; Provisional
 7-301 1.76e-05

alkyl hydroperoxide reductase subunit F; Provisional


Pssm-ID: 237942 [Multi-domain]  Cd Length: 517  Bit Score: 46.30  E-value: 1.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIET-LVIEK--GNVVE--SIYNYPthqtffssSDKLSIGdipfivedskPRRNQALvyyR 81
Cdd:PRK15317 215 LVVGGGPAGAAAAIYAARKGIRTgIVAERfgGQVLDtmGIENFI--------SVPETEG----------PKLAAAL---E 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  82 EVVKHHQLNIHPFEEVLTVKKINNKFAITTTKG-VYECKYLTVATGyyGQHNTL----EAE----G-AELPkvfhyfkea 151
Cdd:PRK15317 274 EHVKEYDVDIMNLQRASKLEPAAGLIEVELANGaVLKAKTVILATG--ARWRNMnvpgEDEyrnkGvAYCP--------- 342

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 152 H---PYF-NQNVVIIGGKNSAVDAALELekAG--ANVTVLYRGEQYpKAIKpwILPN-FESLVNHEKITmefNATVTKIT 224
Cdd:PRK15317 343 HcdgPLFkGKRVAVIGGGNSGVEAAIDL--AGivKHVTVLEFAPEL-KADQ--VLQDkLRSLPNVTIIT---NAQTTEVT 414

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 225 --DHSVT---YE--KDGQLIEIDNDYVFAMIGYHPDYDFLKTIgidIHTNEYGTAPVYNREtfETNVEncyiaGVIAAGn 297
Cdd:PRK15317 415 gdGDKVTgltYKdrTTGEEHHLELEGVFVQIGLVPNTEWLKGT---VELNRRGEIIVDARG--ATSVP-----GVFAAG- 483


                 ....
gi 487749130 298 DANT 301
Cdd:PRK15317 484 DCTT 487
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 158-242 1.87e-05

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 42.19  E-value: 1.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  158 NVVIIGGKNSAVDAALELEKAGANVTVLYRGEQ----YPKAIKPWILPNFESLvnheKITMEFNATVTKItdhsvTYEKD 233
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERRDRllpgFDPEIAKILQEKLEKN----GIEFLLNTTVEAI-----EGNGD 71


                  ....*....
gi 487749130  234 GQLIEIDND 242
Cdd:pfam00070  72 GVVVVLTDG 80
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
8-55 4.57e-05

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 40.98  E-value: 4.57e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 487749130    8 IIGGGPCGLSAAIEQKKKGIETLVIEKGNVV----------ESIYNYPTHqTFFSSSD 55
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLggnaysyrvpGYVFDYGAH-IFHGSDE 57
COG2509 COG2509
FAD-dependent dehydrogenase [General function prediction only];
7-39 5.33e-05

FAD-dependent dehydrogenase [General function prediction only];


Pssm-ID: 441999 [Multi-domain]  Cd Length: 466  Bit Score: 44.72  E-value: 5.33e-05
                         10        20        30
                 ....*....|....*....|....*....|...
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNVVE 39
Cdd:COG2509   34 VIVGAGPAGLFAALELAEAGLKPLVLERGKDVE 66
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 8-187 5.81e-05

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 44.21  E-value: 5.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130   8 IIGGGPCGLSAAIEQKKKGIETLV-------------------IEKGNVVESIYNYPTHQTFFSSSDKlsigdipfIVED 68
Cdd:PRK12770  23 IIGAGPAGLAAAGYLACLGYEVHVydklpepgglmlfgipefrIPIERVREGVKELEEAGVVFHTRTK--------VCCG 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130  69 SKPRRNQALVYYREVVKhhqlnihpFEEVltvkkINNKFAITTTKGVYECKYLTVatgyygqhntleaEGAELPKVF--- 145
Cdd:PRK12770  95 EPLHEEEGDEFVERIVS--------LEEL-----VKKYDAVLIATGTWKSRKLGI-------------PGEDLPGVYsal 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 487749130 146 ---HYFKEAH----------PYFNQNVVIIGGKNSAVDAALELEKAGA-NVTVLYR 187
Cdd:PRK12770 149 eylFRIRAAKlgylpwekvpPVEGKKVVVVGAGLTAVDAALEAVLLGAeKVYLAYR 204
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 7-53 6.29e-05

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 44.20  E-value: 6.29e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 487749130    7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNVVESiynypthQTFFSS 53
Cdd:pfam00890   3 LVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGG-------ATAWSS 42
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 7-34 9.07e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 44.05  E-value: 9.07e-05
                         10        20
                 ....*....|....*....|....*...
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEK 34
Cdd:COG1053    7 VVVGSGGAGLRAALEAAEAGLKVLVLEK 34
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 7-38 9.92e-05

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 43.67  E-value: 9.92e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNVV 38
Cdd:COG1232    5 AVIGGGIAGLTAAYRLAKAGHEVTVLEASDRV 36
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 7-34 1.38e-04

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 43.00  E-value: 1.38e-04
                         10        20
                 ....*....|....*....|....*...
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEK 34
Cdd:COG0654    7 LIVGGGPAGLALALALARAGIRVTVVER 34
PRK07208 PRK07208
hypothetical protein; Provisional
 1-57 2.76e-04

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 42.57  E-value: 2.76e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487749130   1 MQTIESIIIGGGPCGLSAAIEQKKKGIETLVIEKGNVVESIYNYPTHQ---------TFFSSSDKL 57
Cdd:PRK07208   2 TNKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGISRTVTYKgnrfdigghRFFSKSPEV 67
PRK12779 PRK12779
putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; ...
 157-190 3.06e-04

putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; Provisional


Pssm-ID: 183740 [Multi-domain]  Cd Length: 944  Bit Score: 42.51  E-value: 3.06e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 487749130 157 QNVVIIGGKNSAVDAALELEKAGANVTVLYRGEQ 190
Cdd:PRK12779 448 KEVFVIGGGNTAMDAARTAKRLGGNVTIVYRRTK 481
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 7-34 3.40e-04

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 41.93  E-value: 3.40e-04
                          10        20
                  ....*....|....*....|....*...
gi 487749130    7 IIIGGGPCGLSAAIEQKKKGIETLVIEK 34
Cdd:pfam01494   5 LIVGGGPAGLMLALLLARAGVRVVLVER 32
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 149-308 4.46e-04

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 42.02  E-value: 4.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 149 KEAHPyfNQNVVIIGGKNSAVDAALELEKAGA-NVTVLYR--GEQYPK-------------AIKPWILP-NFESLVNHEK 211
Cdd:PRK12814 318 TALHP--GKKVVVIGGGNTAIDAARTALRLGAeSVTILYRrtREEMPAnraeieealaegvSLRELAAPvSIERSEGGLE 395

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749130 212 IT---MEFNAtvtkiTDHS-----VTYEkdGQLIEIDNDYVFAMIGYHPDYDFLKTIGidIHTNEYGTAPVyNRETFETN 283
Cdd:PRK12814 396 LTaikMQQGE-----PDESgrrrpVPVE--GSEFTLQADTVISAIGQQVDPPIAEAAG--IGTSRNGTVKV-DPETLQTS 465

                        170       180
                 ....*....|....*....|....*
gi 487749130 284 VENCYIAGVIAAGNDANTIFIENGK 308
Cdd:PRK12814 466 VAGVFAGGDCVTGADIAINAVEQGK 490
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-38 1.91e-03

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 39.83  E-value: 1.91e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 487749130   1 MQTIESIIIGGGPCGLSAAIEQKKKGIETLVIEKGNVV 38
Cdd:COG1233    1 MMMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTP 38
PRK07233 PRK07233
hypothetical protein; Provisional
 8-38 1.97e-03

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 39.87  E-value: 1.97e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 487749130   8 IIGGGPCGLSAAIEQKKKGIETLVIEKGNVV 38
Cdd:PRK07233   4 IVGGGIAGLAAAYRLAKRGHEVTVFEADDQL 34
PRK06475 PRK06475
FAD-binding protein;
7-41 4.45e-03

FAD-binding protein;


Pssm-ID: 180582 [Multi-domain]  Cd Length: 400  Bit Score: 38.65  E-value: 4.45e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEKGNVVESI 41
Cdd:PRK06475   6 LIAGAGVAGLSAALELAARGWAVTIIEKAQELSEV 40
PRK06847 PRK06847
hypothetical protein; Provisional
 1-34 6.98e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 37.93  E-value: 6.98e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 487749130   1 MQTIESI-IIGGGPCGLSAAIEQKKKGIETLVIEK 34
Cdd:PRK06847   1 MAAVKKVlIVGGGIGGLSAAIALRRAGIAVDLVEI 35
PRK12842 PRK12842
putative succinate dehydrogenase; Reviewed
 7-34 8.41e-03

putative succinate dehydrogenase; Reviewed


Pssm-ID: 237224 [Multi-domain]  Cd Length: 574  Bit Score: 37.75  E-value: 8.41e-03
                         10        20
                 ....*....|....*....|....*...
gi 487749130   7 IIIGGGPCGLSAAIEQKKKGIETLVIEK 34
Cdd:PRK12842  13 LVIGSGAGGLSAAITARKLGLDVVVLEK 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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