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Conserved domains on  [gi|487749754|ref|WP_001831695|]
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MULTISPECIES: ABC transporter permease [Staphylococcus]

Protein Classification

ABC transporter permease( domain architecture ID 10003093)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 7-257 4.27e-77

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


:

Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 235.43  E-value: 4.27e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   7 WLLVPYLLWMVIFIIIPVILLVYFSFID------IHGHFSFTNYEQVFSTR-YLKMFIDSIWYAALITMITLIISYPAAY 79
Cdd:COG1176   13 LLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTDPlYLKVLLRTLWIALLTTLICLLLGYPIAY 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  80 FISYS--RFQNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQI--PKLNLLFTSGAFLLVASYIYIPFMILP 155
Cdd:COG1176   93 FLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLidEPLRLLYTEFAVVIGLVYVYLPFMVLP 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 156 IFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTAIEEQFLTIQ 235
Cdd:COG1176  173 LYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQFLSAL 252

                        250       260
                 ....*....|....*....|..
gi 487749754 236 NYGLGSTIALFLIIFMAFLLII 257
Cdd:COG1176  253 NWPLAAALAVVLLLIVLLVLLL 274
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 7-257 4.27e-77

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 235.43  E-value: 4.27e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   7 WLLVPYLLWMVIFIIIPVILLVYFSFID------IHGHFSFTNYEQVFSTR-YLKMFIDSIWYAALITMITLIISYPAAY 79
Cdd:COG1176   13 LLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTDPlYLKVLLRTLWIALLTTLICLLLGYPIAY 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  80 FISYS--RFQNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQI--PKLNLLFTSGAFLLVASYIYIPFMILP 155
Cdd:COG1176   93 FLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLidEPLRLLYTEFAVVIGLVYVYLPFMVLP 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 156 IFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTAIEEQFLTIQ 235
Cdd:COG1176  173 LYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQFLSAL 252

                        250       260
                 ....*....|....*....|..
gi 487749754 236 NYGLGSTIALFLIIFMAFLLII 257
Cdd:COG1176  253 NWPLAAALAVVLLLIVLLVLLL 274
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 15-257 1.95e-40

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 140.98  E-value: 1.95e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  15 WMVIFIIIPVILLVYFSFID------IHGHFSFTNYEQVFSTRYLKMFIDSIWYAALITMITLIISYPAAYFISY--SRF 86
Cdd:PRK09497  18 WLVLFVFLPNLMIIGTSFLTrddanfVKMVFTLDNYTRLLDPLYAEVLLHSLNMALIATLACLVLGYPFAWFLAKlpHKV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  87 QNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQI--PKLNLLFTSGAFLLVASYIYIPFMILPIFNSMKAIP 164
Cdd:PRK09497  98 RPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVidTPIRIMFTESAVIIGLVYILLPFMVLPLYSSIEKLD 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 165 NNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTAIEEQFLTIQNYGLGSTIA 244
Cdd:PRK09497 178 KPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNIRDWPFGAATS 257

                        250
                 ....*....|...
gi 487749754 245 LFLIIFMAFLLII 257
Cdd:PRK09497 258 ITLTIVMGLMLLV 270
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 8-255 4.90e-14

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 71.25  E-value: 4.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754    8 LLVPYLLWMVIFIIIPVILLVYFSFIDIHGHF-SFTNYEQVFST-RYLKMFIDSIWYAALITMITLIISYPAAYFISYSR 85
Cdd:TIGR03262   6 LLAGMILALLLFLLLPLLALLTKSVYDSDGDFiGLANFAEYFATpGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   86 --FQNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQIpklnllftSGAFLLVASYIY--IPFMILPIFNSMK 161
Cdd:TIGR03262  86 ipGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSI--------YGFWGIVIGEVFytFPHALMILVTALS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  162 AIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNkvINV-GTAIEEQFLTIQNYGLG 240
Cdd:TIGR03262 158 LADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGD--YNVlATDIYKQVIGQQNFPMG 235

                         250
                  ....*....|....*..
gi 487749754  241 STIALFLII--FMAFLL 255
Cdd:TIGR03262 236 AVVGVLLLLpaLLAFGI 252
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 56-254 7.82e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 42.27  E-value: 7.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  56 FIDSIWYAALITMITLIISYPAAYFISYSRFQNILLMLLIIPTWINLLLKTYAFIGLLghdgvinqaLHIFQIPKLNLLF 135
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVL---------LFGVLLGWGILPG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 136 TSGAFLLVASYIYIPFMILPIFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLI 215
Cdd:cd06261   72 LGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFL 151

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 487749754 216 AGNKVINVGTAIEEQFLTIQNYGLGSTIALFLIIFMAFL 254
Cdd:cd06261  152 GGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 7-257 4.27e-77

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 235.43  E-value: 4.27e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   7 WLLVPYLLWMVIFIIIPVILLVYFSFID------IHGHFSFTNYEQVFSTR-YLKMFIDSIWYAALITMITLIISYPAAY 79
Cdd:COG1176   13 LLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTDPlYLKVLLRTLWIALLTTLICLLLGYPIAY 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  80 FISYS--RFQNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQI--PKLNLLFTSGAFLLVASYIYIPFMILP 155
Cdd:COG1176   93 FLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLidEPLRLLYTEFAVVIGLVYVYLPFMVLP 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 156 IFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTAIEEQFLTIQ 235
Cdd:COG1176  173 LYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQFLSAL 252

                        250       260
                 ....*....|....*....|..
gi 487749754 236 NYGLGSTIALFLIIFMAFLLII 257
Cdd:COG1176  253 NWPLAAALAVVLLLIVLLVLLL 274
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 15-257 1.95e-40

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 140.98  E-value: 1.95e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  15 WMVIFIIIPVILLVYFSFID------IHGHFSFTNYEQVFSTRYLKMFIDSIWYAALITMITLIISYPAAYFISY--SRF 86
Cdd:PRK09497  18 WLVLFVFLPNLMIIGTSFLTrddanfVKMVFTLDNYTRLLDPLYAEVLLHSLNMALIATLACLVLGYPFAWFLAKlpHKV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  87 QNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQI--PKLNLLFTSGAFLLVASYIYIPFMILPIFNSMKAIP 164
Cdd:PRK09497  98 RPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVidTPIRIMFTESAVIIGLVYILLPFMVLPLYSSIEKLD 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 165 NNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTAIEEQFLTIQNYGLGSTIA 244
Cdd:PRK09497 178 KPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNIRDWPFGAATS 257

                        250
                 ....*....|...
gi 487749754 245 LFLIIFMAFLLII 257
Cdd:PRK09497 258 ITLTIVMGLMLLV 270
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 10-257 4.81e-34

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 125.21  E-value: 4.81e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  10 VPYLlWMVIFIIIPVILLVYFSFIDI--------------HGHFSFT----NYEQVFS-TRYLKMFIDSIWYAALITMIT 70
Cdd:PRK10683  35 LPYL-WLILLFLLPFLIVFKISLAEMaraippytdlmewaDGQLSITlnlgNFLQLTDdPLYFDAYLQSLQVAAISTLCC 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  71 LIISYPAAYFISYSR--FQNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQI--PKLNLLFTSGAFLLVASY 146
Cdd:PRK10683 114 LLIGYPLAWAVAHSKpsTRNILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVidQPLTILHTNLAVYIGIVY 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 147 IYIPFMILPIFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTA 226
Cdd:PRK10683 194 AYLPFMVLPIYTALTRIDYSLVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRV 273

                        250       260       270
                 ....*....|....*....|....*....|.
gi 487749754 227 IEEQFLTIQNYGLGSTIAlfliIFMAFLLII 257
Cdd:PRK10683 274 LWQEFFNNRDWPVASAVA----IIMLLLLIV 300
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
5-257 3.19e-24

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 101.01  E-value: 3.19e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   5 NKWLLVPYLLWMVIFIIIPVILLVYFSFIDIHGHFSftnyEQVFSTRYLKMFIDSIWYAALITMITLIISYPAAYFISYS 84
Cdd:COG1178    9 PRLLLLLLALLLALLVLLPLLALLLRAFTDGLANFW----ALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLLART 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  85 RF------QNILLMLLIIPTWINlllkTYAFIGLLGHDGVINQALHIFQIPKLNLLFTSGAFLLVASYIYIPFMILPIFN 158
Cdd:COG1178   85 DFpgrrllRWLLLLPLALPPYVV----ALAWIALFGPNGLLNTLLRALFGLEPPDIYGLGGIILVLVLFNYPYVYLLLRA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 159 SMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNkVINVGTAIEEQFLTIQNYG 238
Cdd:COG1178  161 ALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVLGGG-YTTLTTAIYQAWLGDFDLG 239

                        250
                 ....*....|....*....
gi 487749754 239 LGSTIALFLIIFMAFLLII 257
Cdd:COG1178  240 AAAALALVLLLLVLLLLLL 258
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 2-257 1.00e-18

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 82.85  E-value: 1.00e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   2 HNINKWLLVPYLLWMVIFIIIPVILLVYFSFID------IHGHFSFTNYEQVFS-TRYLKMFIDSIWYAALITMITLIIS 74
Cdd:COG1177    2 SRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDswfltfPPEGFTLRWYAELFSdPRLLDALLNSLLIALLSTLLATVLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  75 YPAAYFISYSRF--QNILLMLLIIP-------TWINLLLkTYAFIGLLGhdgvinqalhifqipklnllftsGAFLLVAS 145
Cdd:COG1177   82 TPAALALARYRFrgRRLLLALLLLPlvvpgivLGVALLL-LFSALGLSG-----------------------GLWGLILA 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 146 YI--YIPFMILPIFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINV 223
Cdd:COG1177  138 HVvfTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVTTL 217

                        250       260       270
                 ....*....|....*....|....*....|....
gi 487749754 224 GTAIEEQfLTIQNYGLGSTIALFLIIFMAFLLII 257
Cdd:COG1177  218 PVYIYSM-IRRGISPEINALSTLLILLSLLLLLL 250
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
7-257 9.21e-18

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 80.95  E-value: 9.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   7 WLLVPYLLWMVIFIIIPVILLVYFSFIDIHGHFS------FTNYEQVFSTRYlkmFIDSIWYAALITMITLIISYPAAYF 80
Cdd:COG1175   22 LFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGPppefvgLDNYARLFTDPR---FWNALGNTLLFTVVSVPLQLVLGLL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  81 ISY-----SRFQNILLMLLIIPTWINLLLKTYAFIGLLGHD-GVINQALHIFQIPKLNLLFTSG----AFLLVASYIYIP 150
Cdd:COG1175   99 LALllnrkLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGALGLEPINWLGDPSlalpAVIIVTVWKGTG 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 151 FMILPIFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLF----MITRLIAGNKVINVGTA 226
Cdd:COG1175  179 FNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFdlvyVLTGGGPGNSTTTLVLY 258

                        250       260       270
                 ....*....|....*....|....*....|.
gi 487749754 227 IEEQFLTIQNYGLGSTIALFLIIFMAFLLII 257
Cdd:COG1175  259 IYQTAFQQFDFGYASAIAVVLFLIILVLTLL 289
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
6-257 3.65e-17

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 80.59  E-value: 3.65e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   6 KWLLVPYLLWMVIFIIIPVILLVYFSFID-IHGHFSFTNYEQVF-STRYLKMFIDSIWYAALITMITLIISYPAAYFI-- 81
Cdd:COG1178  288 WLALALCLLLVLLGLLLPLLALLLWSLTKaLDDNLTLDNYRFVLlDPSLLRALLNSLLLALLAALLAVLLALLLAYLVrr 367

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  82 SYSRFQNILLMLLIIPtwinlllktYAFIGLlghdgVINQALHIFQIPKLNLLFTSGAFLLVASYI--YIPFMILPIFNS 159
Cdd:COG1178  368 RRGRLARLLDRLAMLP---------YAVPGI-----VLGLGLLLLFNRPLPLLLYGTLAILVLAYVvrFLPFALRSLEAA 433

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 160 MKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTAIEEQFLTIQnYGL 239
Cdd:COG1178  434 LAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGFETLAVLIYQLASSGR-YGE 512

                        250
                 ....*....|....*...
gi 487749754 240 GSTIALFLIIFMAFLLII 257
Cdd:COG1178  513 AAALALLLVLVSLLPVLL 530
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 59-218 2.12e-15

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 73.16  E-value: 2.12e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  59 SIWYAALITMITLIISYPAAYFISYSRFQ-----NILLMLLII--PTWINLLLktyafIGLLGHDGVINQALH-IFQIPk 130
Cdd:COG4149   12 SLKVALIATLLLLLLGIPLAWWLARTRFRgkgllEALVTLPLVlpPTVLGFYL-----LLLFGRNGPLGQLLEeLFGIS- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 131 lnLLFTSGAfLLVASYIY-IPFMILPIFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLF 209
Cdd:COG4149   86 --LVFTWTG-AVLASVVVsLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAFARALGEF 162


                 ....*....
gi 487749754 210 MITRLIAGN 218
Cdd:COG4149  163 GATLMFAGN 171
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 6-259 4.79e-14

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 70.16  E-value: 4.79e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   6 KWLLVPYLLWMVIFIIIPVILLVYFSFidihgHFSFTNY-EQVFSTRYLKMFIDSIWYAALITMITLIISYPAAYFISYS 84
Cdd:COG0555   10 GLTLGLTLLYLSLIVLLPLAALVLKAA-----GLGWAEFwAVLTSPRVLAALKLSLGTALIAALINLVFGLPLAWVLVRY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  85 RF--QNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQIpklNLLFTSGAFLLVASYIYIPFMILPIFNSMKA 162
Cdd:COG0555   85 RFpgKRLVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGI---KVAFTPLGIVLAQTFVSLPFVVRTVQPVLEE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 163 IPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTAIEEQFLTIQNYGLG-- 240
Cdd:COG0555  162 LDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEFGAVIFIAGNLPMKTEILPLLIYLKLEEGDYAga 241

                        250
                 ....*....|....*....
gi 487749754 241 STIALFLIIFMAFLLIITK 259
Cdd:COG0555  242 TAIALVLLLISFLLLLLIN 260
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 8-255 4.90e-14

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 71.25  E-value: 4.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754    8 LLVPYLLWMVIFIIIPVILLVYFSFIDIHGHF-SFTNYEQVFST-RYLKMFIDSIWYAALITMITLIISYPAAYFISYSR 85
Cdd:TIGR03262   6 LLAGMILALLLFLLLPLLALLTKSVYDSDGDFiGLANFAEYFATpGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRSR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   86 --FQNILLMLLIIPTWINLLLKTYAFIGLLGHDGVINQALHIFQIpklnllftSGAFLLVASYIY--IPFMILPIFNSMK 161
Cdd:TIGR03262  86 ipGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSI--------YGFWGIVIGEVFytFPHALMILVTALS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  162 AIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNkvINV-GTAIEEQFLTIQNYGLG 240
Cdd:TIGR03262 158 LADGRLYEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGD--YNVlATDIYKQVIGQQNFPMG 235

                         250
                  ....*....|....*..
gi 487749754  241 STIALFLII--FMAFLL 255
Cdd:TIGR03262 236 AVVGVLLLLpaLLAFGI 252
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 7-249 3.75e-11

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 61.94  E-value: 3.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   7 WLLVPyLLWMVIFIIIPVILLVYFSFIDIHGhFSFTNYEQVF-STRYLKMFIDSIWYAALITMITLIISYPAAYFISYSR 85
Cdd:PRK15050  27 WLLLP-LLVLAPLVVYPLVRVVLQSLTGEHG-LGLATYRAVLgSPDFRGALLTTLQIAFASTAGCLVLGVLLALVLAFVP 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  86 FQNILLMLLIIPTWINL--LLKTYAFIGLLGHDGVIN---QALHIFQIPKLNLLFTSGAFLLVASYIYIPFMILPIFNSM 160
Cdd:PRK15050 105 FPGASLVGRFIDTFVAFpsFLITLAFTFLYGSAGSVNialQRLFGLEAPPLDFLYSPGGVILAEITFYTPFVVRPLLAAF 184

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 161 KAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGNKVINVGTAIEEQFLTIQNYGLG 240
Cdd:PRK15050 185 AQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEFGIVLFTGAKDVVTLPVLIYSKAIVDFDYPTA 264


                 ....*....
gi 487749754 241 STIALFLII 249
Cdd:PRK15050 265 CAIAVVNLA 273
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 4-194 9.48e-09

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 54.72  E-value: 9.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   4 INKWLLVPYLLWMVIFIIIPVILLVYFSFID-----------IHGHFSFTNYEQVFS-TRYLKMFIDSIWYAALITMITL 71
Cdd:COG0395   12 LGRILLYLLLILLALLFLFPLYWMVVTSFKPpaeifsgppslLPSEFTLENYRAAFTdGPFGRYLLNSLIVAVVSTVLSL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  72 IISYPAAYFISYSRF--QNILLMLLIIPTWIN---LLLKTYAFIGllghdgvinqalhifqipKLNLLFTSGAFLLVASY 146
Cdd:COG0395   92 LLSSLAAYALARFRFrgRKLLFLLILATLMIPgqvLLIPLYLLFR------------------QLGLLNTYWGLILPYLA 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 487749754 147 IYIPFMILPIFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGI 194
Cdd:COG0395  154 FGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPAL 201
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 4-197 9.54e-06

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 45.75  E-value: 9.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   4 INKWLLVPYLLWMVIFIIIPVILLVYFSFIDIH-----GHFSFTNYEQVFSTRYL-KMFIDSIWYAALITMITLIISYPA 77
Cdd:PRK09500   1 MGRLLRGGFMTLVYAYLYIPIIILIVNSFNSSRfginwKGFTTKWYELLFNNDSLlQAAQHSLTMAVFSATFATLIGSLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  78 AYFISYSRFQNillmlliiptwiNLLLKTYAFIGLLGHDGVINQALHI-FQIPKLNLLFTSgafLLVASYIY-IPFMILP 155
Cdd:PRK09500  81 AVALYRYRFRG------------KKFVSGMLFVVMMSPDIVMAISLLVlFMLLGIQLGFWS---LLFAHITFcLPFVVVT 145

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 487749754 156 IFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTG 197
Cdd:PRK09500 146 VYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAG 187
cysT CHL00187
sulfate transport protein; Provisional
 2-218 1.29e-05

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 45.39  E-value: 1.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   2 HNINKWLLVPYLLWMVIFIIIPVILLVYFSFIDIHGHFSFTNYEQVFSTRYLKMFIDSIwYAALITMI-TLIISYPAAYF 80
Cdd:CHL00187   7 SLKFSSIYIISLSYIIFLLVLPILALLIKASQQPWSDFLQKATEPIALSAYSLTLSMAL-IAALINGFfGLLIAWVLVRY 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  81 ISYSR--FQNILLMLLIIPTWIN--LLLKTYAFIGLLGHdgvinqalhIFQIPKLNLLFTSGAFLLVASYIYIPFMILPI 156
Cdd:CHL00187  86 NFPGKrlLDAAVDLPFALPTSVAglTLATVYGDNGWIGH---------LLSHLGIQIVFTKLGVLLAMIFVSFPFVVRTI 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487749754 157 FNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLIAGN 218
Cdd:CHL00187 157 QPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEYGSIVIISSN 218
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 56-254 7.82e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 42.27  E-value: 7.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  56 FIDSIWYAALITMITLIISYPAAYFISYSRFQNILLMLLIIPTWINLLLKTYAFIGLLghdgvinqaLHIFQIPKLNLLF 135
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVL---------LFGVLLGWGILPG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754 136 TSGAFLLVASYIYIPFMILPIFNSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQVTFIPALSLFMITRLI 215
Cdd:cd06261   72 LGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFL 151

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 487749754 216 AGNKVINVGTAIEEQFLTIQNYGLGSTIALFLIIFMAFL 254
Cdd:cd06261  152 GGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 60-218 3.51e-03

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 38.02  E-value: 3.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754   60 IWYAALITMITLIISYP----AAYFISY-------SRFQNILLMLLIIPTWInlllktYAFIGLLghdgVINQAL--HIF 126
Cdd:TIGR02138  65 IVGTLITSLIALLIAVPvgigIAIFLSEiapkrvrSVLKPVVELLAGIPSVV------YGFWGLF----VLVPFLkpHFQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  127 QIPKLNLLFTSG-AFLLVASYIYIPFMILPIFNSM-----KAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGVQV 200
Cdd:TIGR02138 135 PFLGSNLGLIPLfGGPILTAGIVLAIMILPTIASIsrdalRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAVVL 214

                         170
                  ....*....|....*...
gi 487749754  201 TFIPALSLFMITRLIAGN 218
Cdd:TIGR02138 215 GLGRALGETMAVTMVIGN 232
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 18-198 9.42e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 36.99  E-value: 9.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  18 IFIIIPVILLVYF------SFIDIHGHFSFtnyeqVFSTRYLKMFIDSIWYAA-------LITMITLIISYP----AAYF 80
Cdd:COG0573   29 LLSILILLLIVLFllieslPAFQEVGLLEF-----LTGTEWNPVSSNGEFGILplivgtlLVSLIALLIAVPlglgIAIF 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487749754  81 ISY---SRFQNILLMLL----IIPTWInlllktYAFIGLLghdgVINQAL-HIFQIPklnllfTSGAFLLVASyIYIPFM 152
Cdd:COG0573  104 LSEyapPRLRRILKPAIellaGIPSVV------YGFWGLF----VLVPLLrDLFPWP------PSGFSLLTAG-IVLAIM 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 487749754 153 ILPIF-----NSMKAIPNNILQASNDLGASTFTTFRKVIVPLTREGIKTGV 198
Cdd:COG0573  167 ILPTItslsrDALRAVPRSLREAALALGATRWETIRKVVLPAARSGIIAAV 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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