|
Name |
Accession |
Description |
Interval |
E-value |
| secA2 |
TIGR03714 |
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA ... |
9-771 |
0e+00 |
|
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 163426 [Multi-domain] Cd Length: 762 Bit Score: 1353.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 9 INNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGA 88
Cdd:TIGR03714 1 INNLRLKKLRKILNKINALKGKMATLSDEELQAKTAEFKNRLVEGE-SLDDILPEAYAVVREADKRVLGMFPYDVQVLGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 89 IAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEYEYAENEK 168
Cdd:TIGR03714 80 IVLHQGNIAEMKTGEGKTLTATMPLYLNALTGKGAMLVTTNDYLAKRDAEEMGPVYEWLGLTVSLGVVDDPDEEYDANEK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 169 YELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETL 248
Cdd:TIGR03714 160 RKIYNSDIVYTTNSALGFDYLIDNLASNKEGKFLRPFNYVIVDEVDSVLLDSAQTPLVISGAPRVQSNLYHIADTFVRTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 249 EKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRML 328
Cdd:TIGR03714 240 KEDVDYIFKKDKKEVWLTDKGIEKAEQYFKIDNLYSEEYFELVRHINLALRAHYLFKRNKDYVVTNGEVVLLDRITGRLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 329 PGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRP 408
Cdd:TIGR03714 320 EGTKLQSGIHQAIEAKEHVELSKETRAMASITYQNLFKMFNKLSGMTGTGKVAEKEFIETYSLSVVKIPTNKPIIRIDYP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 409 DRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVAT 488
Cdd:TIGR03714 400 DKIYATLPEKLMATLEDVKEYHETGQPVLLITGSVEMSEIYSELLLREGIPHNLLNAQNAAKEAQIIAEAGQKGAVTVAT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 489 SMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWSNSNLAENKNLQTMD 568
Cdd:TIGR03714 480 SMAGRGTDIKLGKGVAELGGLAVIGTERMENSRVDLQLRGRSGRQGDPGSSQFFVSLEDDLIKRWSPSWLKKYYKKYSVK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 569 ASKLESSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDFNFEQLARDVFTKDV 648
Cdd:TIGR03714 560 DSKLKPSALFKRRFRKIVEKAQRASEDKGESAREQTNEFEESLSIQRENIYAERNRLIEGSDFLDDDVDQIIDDVFNMYA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 649 KNLDLSSERALVNYIYENLSFVFDEDVSNINMQNDEEIIQFLIQQFTQQFNNRLEVAADSYLKLRFIQKSILKAIDSEWI 728
Cdd:TIGR03714 640 EEQDLSNKSLLKRFILENLSYQFKNDPDEFDLKNKEAIKDFLKEIADKELSEKKKVLNNDYLFNDFERLSILKAIDENWI 719
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 487751202 729 EQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIK 771
Cdd:TIGR03714 720 EQVDYLQQLKTVVTNRQNGQRNPIFEYHKEALESYEYMKKEIK 762
|
|
| PRK09200 |
PRK09200 |
preprotein translocase subunit SecA; Reviewed |
1-796 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 236408 [Multi-domain] Cd Length: 790 Bit Score: 1274.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 1 MAKGVNQIINNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYP 80
Cdd:PRK09200 1 MKKKLLGDIDKRRLKKYRKIVKQINKLEGKMSSLSDEELRQKTIEFKERLASGK-TLDDILPEAFAVVREAAKRVLGMRP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 81 KDVQILGAIAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPE 160
Cdd:PRK09200 80 YDVQLIGALVLHEGNIAEMQTGEGKTLTATMPLYLNALEGKGVHLITVNDYLAKRDAEEMGQVYEFLGLTVGLNFSDIDD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 161 yeyaENEKYELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHI 240
Cdd:PRK09200 160 ----ASEKKAIYEADIIYTTNSELGFDYLRDNLADSKEDKVQRPLNYAIIDEIDSILLDEAQTPLIISGKPRVQSNLYHI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 241 VKTFVETLEKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLI 320
Cdd:PRK09200 236 AAKFVKTLEEDVDYEFDEEKKEVWLTDQGIEKAESYFGIDNLYSLEHQVLYRHIILALRAHVLFKRDVDYIVYDGEIVLV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 321 DRITGRMLPGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHS 400
Cdd:PRK09200 316 DRFTGRVLPGRKLQDGLHQAIEAKEGVEITEENRTMASITIQNLFRMFPKLSGMTGTAKTEEKEFFEVYNMEVVQIPTNR 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 401 PIERDDRPDRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQ 480
Cdd:PRK09200 396 PIIRIDYPDKVFVTLDEKYKAVIEEVKERHETGRPVLIGTGSIEQSETFSKLLDEAGIPHNLLNAKNAAKEAQIIAEAGQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 481 LSAVTVATSMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWSNSNLAE 560
Cdd:PRK09200 476 KGAVTVATNMAGRGTDIKLGEGVHELGGLAVIGTERMESRRVDLQLRGRSGRQGDPGSSQFFISLEDDLLKRFAPEELEK 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 561 NKNLQTMDASKlESSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDFNFEQLA 640
Cdd:PRK09200 556 LKKKLKTDAQR-LTGLLFNRKVHKIVVKAQRISEGAGYSAREYALELDDVINIQRDVVYKERNRLLEEDDRDLIDIVILM 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 641 RDVFTKDVKNLDLSSERALVNYIYENLSFVFDEDVSNINMQNDEEIIQFLIQQFTQQFNNRLEVAADSYLKLRFIQKSIL 720
Cdd:PRK09200 635 IDVYLEAVAEEYLLEKSLLEEWIYENLSFQLNEILSNTNFPDKKEVVQFLLEEAEKQLKEKRNKLPSATLYNQFLRKVAL 714
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487751202 721 KAIDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMVRNLCLSILAFDKDGDMVIHFP 796
Cdd:PRK09200 715 KAIDQNWVEQVDALQQLKEGIGLRQYGQRNPIREYQKEALESFEYMYENIKKDMVRNLLLSLLVFDKEGEIVIHFP 790
|
|
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
14-778 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 682.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 14 LRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGAIAMHQ 93
Cdd:COG0653 17 LKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLANGE-TLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGIVLHQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 94 GNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSlgfVDIPEYEYAenEKYELYH 173
Cdd:COG0653 96 GKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLSVG---VIVHGMDPE--ERRAAYA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 174 HDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLEKDKD 253
Cdd:COG0653 171 ADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYYRINKLVPRLKRDGD 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 254 FIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLPGTKL 333
Cdd:COG0653 251 YTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENIELVHHLNQALRAHALFKRDVDYIVKDGEVVIVDEFTGRLMPGRRY 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 334 QSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRPDRVFA 413
Cdd:COG0653 331 SDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYGLDVVVIPTNRPMIRKDEPDLVYK 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 414 NGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVATSMAGR 493
Cdd:COG0653 411 TEEEKFNAVVEDIKERHEKGQPVLVGTTSIEKSELLSKLLKKEGIPHNVLNAKQHEREAEIVAQAGRPGAVTIATNMAGR 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 494 GTDIKL---------------------------------SKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQ 540
Cdd:COG0653 491 GTDIVLggnpeflaaaeladrgleweeaiakikaewqaeHEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSR 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 541 IFVSLDDDLVKRWSNSNLaenKNLqtMDASKL-ESSALFKKRV-KSIvNKAQRVSEEtamKNREM----------ANEfe 608
Cdd:COG0653 571 FYLSLEDDLMRIFGSDRI---KGM--MDKLGMeEGEPIEHKMVsKAI-ENAQKKVEG---RNFDIrknlleyddvMND-- 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 609 ksisvQRDKIYAERNHILEASDFDDfNFEQLARDVFTK---------------DVKNLdlssERALVNYIYENLSFVFDE 673
Cdd:COG0653 640 -----QRKVIYEQRREILEGEDLSE-TILDMREDVIEDlvdeyipegsypeqwDLEGL----EEALKELFGLDLPIEEWL 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 674 DVSNInmqNDEEIIQFLIQQFTQQFNNRLEVAADSYlkLRFIQKSI-LKAIDSEWIEQVDNLQQLKASVNNRQNGQRNVI 752
Cdd:COG0653 710 DEEGL---DEEELRERLLEAADEAYEEKEEELGPEV--MRELERVVlLQVLDRKWREHLDAMDHLRQGIGLRGYAQKDPL 784
|
810 820
....*....|....*....|....*.
gi 487751202 753 FEYHKVALETYEYMSEDIKRKMVRNL 778
Cdd:COG0653 785 VEYKREAFELFEEMLDSIKEEVVRYL 810
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
10-386 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 570.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 10 NNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGAI 89
Cdd:smart00957 9 NDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAEGE-SLDDLLPEAFAVVREAAKRVLGMRHFDVQLIGGI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 90 AMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEyeyaeNEKY 169
Cdd:smart00957 88 VLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIVSGMSP-----EERR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 170 ELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISG-APRVQSNLFHIVKTFVETL 248
Cdd:smart00957 163 AAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGpAEDESSDLYHRADKFVPRL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 249 EKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRML 328
Cdd:smart00957 243 KEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPENIELLHHVNQALRAHYLFKRDVDYIVRDGEVVIVDEFTGRVM 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 487751202 329 PGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFF 386
Cdd:smart00957 323 EGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMYKKLSGMTGTAKTEAEEFR 380
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
10-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 532.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 10 NNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGAI 89
Cdd:pfam07517 9 NERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERLREGE-SLDDILPEAFALVREAAKRVLGMRHYDVQLIGGL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 90 AMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEyeyaeNEKY 169
Cdd:pfam07517 88 VLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVITSDMDP-----EERR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 170 ELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLE 249
Cdd:pfam07517 163 AAYNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYREADRLVKSLE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 250 KDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLP 329
Cdd:pfam07517 243 EDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENVELLHHINQALKAHHLFKRDVDYIVRDGEVVIVDEFTGRVMP 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 487751202 330 GTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEF 385
Cdd:pfam07517 323 GRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLYPKLSGMTGTAKTEAEEF 378
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
38-398 |
1.71e-92 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 289.05 E-value: 1.71e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 38 ALQAKTKEFKVYLnDNKASLNHILPQAYATVREASKRVLGMYPKDVQILGAIAMHQGNIAEMQTGEGKTLTATMPLYLNA 117
Cdd:cd17928 1 ELRAKTDELRERL-AKGETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 118 LTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDipeyeYAENEKYELYHHDIVYTTNGRLGFDYLIDNLADDI 197
Cdd:cd17928 80 LTGKGVHVVTVNDYLARRDAEWMGPLYEFLGLTVGVILSD-----MSPDERREAYAADITYGTNNELGFDYLRDNMVTSK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 198 RAKFLPKLNFAIIDEVDSIILDAAQTPLVISGaprvqsnlfhivktfvetlekdkdfivnfnkkevwltdegsekashyf 277
Cdd:cd17928 155 EDLVQRGLNFAIVDEVDSILIDEARTPLIISG------------------------------------------------ 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 278 kvnsiyqqqyfdlvrmihlslrakylfkynldyfifdgeivlidritgrmlpgtklqsglhqaiealenveisqdmsVMA 357
Cdd:cd17928 187 -----------------------------------------------------------------------------TLA 189
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 487751202 358 TITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPT 398
Cdd:cd17928 190 TITFQNYFRLYPKLAGMTGTAKTEAEEFREIYNLDVVVIPT 230
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| secA2 |
TIGR03714 |
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA ... |
9-771 |
0e+00 |
|
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 163426 [Multi-domain] Cd Length: 762 Bit Score: 1353.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 9 INNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGA 88
Cdd:TIGR03714 1 INNLRLKKLRKILNKINALKGKMATLSDEELQAKTAEFKNRLVEGE-SLDDILPEAYAVVREADKRVLGMFPYDVQVLGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 89 IAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEYEYAENEK 168
Cdd:TIGR03714 80 IVLHQGNIAEMKTGEGKTLTATMPLYLNALTGKGAMLVTTNDYLAKRDAEEMGPVYEWLGLTVSLGVVDDPDEEYDANEK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 169 YELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETL 248
Cdd:TIGR03714 160 RKIYNSDIVYTTNSALGFDYLIDNLASNKEGKFLRPFNYVIVDEVDSVLLDSAQTPLVISGAPRVQSNLYHIADTFVRTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 249 EKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRML 328
Cdd:TIGR03714 240 KEDVDYIFKKDKKEVWLTDKGIEKAEQYFKIDNLYSEEYFELVRHINLALRAHYLFKRNKDYVVTNGEVVLLDRITGRLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 329 PGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRP 408
Cdd:TIGR03714 320 EGTKLQSGIHQAIEAKEHVELSKETRAMASITYQNLFKMFNKLSGMTGTGKVAEKEFIETYSLSVVKIPTNKPIIRIDYP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 409 DRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVAT 488
Cdd:TIGR03714 400 DKIYATLPEKLMATLEDVKEYHETGQPVLLITGSVEMSEIYSELLLREGIPHNLLNAQNAAKEAQIIAEAGQKGAVTVAT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 489 SMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWSNSNLAENKNLQTMD 568
Cdd:TIGR03714 480 SMAGRGTDIKLGKGVAELGGLAVIGTERMENSRVDLQLRGRSGRQGDPGSSQFFVSLEDDLIKRWSPSWLKKYYKKYSVK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 569 ASKLESSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDFNFEQLARDVFTKDV 648
Cdd:TIGR03714 560 DSKLKPSALFKRRFRKIVEKAQRASEDKGESAREQTNEFEESLSIQRENIYAERNRLIEGSDFLDDDVDQIIDDVFNMYA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 649 KNLDLSSERALVNYIYENLSFVFDEDVSNINMQNDEEIIQFLIQQFTQQFNNRLEVAADSYLKLRFIQKSILKAIDSEWI 728
Cdd:TIGR03714 640 EEQDLSNKSLLKRFILENLSYQFKNDPDEFDLKNKEAIKDFLKEIADKELSEKKKVLNNDYLFNDFERLSILKAIDENWI 719
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 487751202 729 EQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIK 771
Cdd:TIGR03714 720 EQVDYLQQLKTVVTNRQNGQRNPIFEYHKEALESYEYMKKEIK 762
|
|
| PRK09200 |
PRK09200 |
preprotein translocase subunit SecA; Reviewed |
1-796 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 236408 [Multi-domain] Cd Length: 790 Bit Score: 1274.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 1 MAKGVNQIINNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYP 80
Cdd:PRK09200 1 MKKKLLGDIDKRRLKKYRKIVKQINKLEGKMSSLSDEELRQKTIEFKERLASGK-TLDDILPEAFAVVREAAKRVLGMRP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 81 KDVQILGAIAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPE 160
Cdd:PRK09200 80 YDVQLIGALVLHEGNIAEMQTGEGKTLTATMPLYLNALEGKGVHLITVNDYLAKRDAEEMGQVYEFLGLTVGLNFSDIDD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 161 yeyaENEKYELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHI 240
Cdd:PRK09200 160 ----ASEKKAIYEADIIYTTNSELGFDYLRDNLADSKEDKVQRPLNYAIIDEIDSILLDEAQTPLIISGKPRVQSNLYHI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 241 VKTFVETLEKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLI 320
Cdd:PRK09200 236 AAKFVKTLEEDVDYEFDEEKKEVWLTDQGIEKAESYFGIDNLYSLEHQVLYRHIILALRAHVLFKRDVDYIVYDGEIVLV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 321 DRITGRMLPGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHS 400
Cdd:PRK09200 316 DRFTGRVLPGRKLQDGLHQAIEAKEGVEITEENRTMASITIQNLFRMFPKLSGMTGTAKTEEKEFFEVYNMEVVQIPTNR 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 401 PIERDDRPDRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQ 480
Cdd:PRK09200 396 PIIRIDYPDKVFVTLDEKYKAVIEEVKERHETGRPVLIGTGSIEQSETFSKLLDEAGIPHNLLNAKNAAKEAQIIAEAGQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 481 LSAVTVATSMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWSNSNLAE 560
Cdd:PRK09200 476 KGAVTVATNMAGRGTDIKLGEGVHELGGLAVIGTERMESRRVDLQLRGRSGRQGDPGSSQFFISLEDDLLKRFAPEELEK 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 561 NKNLQTMDASKlESSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDFNFEQLA 640
Cdd:PRK09200 556 LKKKLKTDAQR-LTGLLFNRKVHKIVVKAQRISEGAGYSAREYALELDDVINIQRDVVYKERNRLLEEDDRDLIDIVILM 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 641 RDVFTKDVKNLDLSSERALVNYIYENLSFVFDEDVSNINMQNDEEIIQFLIQQFTQQFNNRLEVAADSYLKLRFIQKSIL 720
Cdd:PRK09200 635 IDVYLEAVAEEYLLEKSLLEEWIYENLSFQLNEILSNTNFPDKKEVVQFLLEEAEKQLKEKRNKLPSATLYNQFLRKVAL 714
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487751202 721 KAIDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMVRNLCLSILAFDKDGDMVIHFP 796
Cdd:PRK09200 715 KAIDQNWVEQVDALQQLKEGIGLRQYGQRNPIREYQKEALESFEYMYENIKKDMVRNLLLSLLVFDKEGEIVIHFP 790
|
|
| PRK12904 |
PRK12904 |
preprotein translocase subunit SecA; Reviewed |
10-778 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237259 [Multi-domain] Cd Length: 830 Bit Score: 702.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 10 NNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGAI 89
Cdd:PRK12904 13 NDRELKRLRKIVDKINALEPEMEKLSDEELKAKTAEFKERLAKGE-TLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 90 AMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEYEyaeneKY 169
Cdd:PRK12904 92 VLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLSVGVILSGMSPEE-----RR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 170 ELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLE 249
Cdd:PRK12904 167 EAYAADITYGTNNEFGFDYLRDNMVFSLEERVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSSELYKRANKIVPTLE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 250 KDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLP 329
Cdd:PRK12904 247 KEGDYTVDEKSRTVGLTEEGIEKAEKLLGIENLYDPENIALVHHLNQALRAHELFKRDVDYIVKDGEVVIVDEFTGRLMP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 330 GTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRPD 409
Cdd:PRK12904 327 GRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYNLDVVVIPTNRPMIRIDHPD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 410 RVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVATS 489
Cdd:PRK12904 407 LIYKTEKEKFDAVVEDIKERHKKGQPVLVGTVSIEKSELLSKLLKKAGIPHNVLNAKNHEREAEIIAQAGRPGAVTIATN 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 490 MAGRGTDIKL------------------------------SKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYS 539
Cdd:PRK12904 487 MAGRGTDIKLggnpemlaaalleeeteeqiakikaewqeeHEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSS 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 540 QIFVSLDDDLVKRWSNSNLaenKNLqtMDASKL-ESSALFKKRVKSIVNKAQRVSEetamknremANEFE--KSI----S 612
Cdd:PRK12904 567 RFYLSLEDDLMRIFGSDRV---KGM--MDRLGMkEGEAIEHKMVTRAIENAQKKVE---------GRNFDirKQLleydD 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 613 V---QRDKIYAERNHILEASDFDDfNFEQLARDVFTKDVK---NLDLSSE----RALVNYIYENlsFVFDEDVSNINMQN 682
Cdd:PRK12904 633 VmndQRKVIYAQRNEILEGEDLSE-TILDMREDVIEDLVDayiPPGSYEEdwdlEGLEEALKTD--FGLELPIEEWLEEG 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 683 --DEEIIQFLIQQFTQQFNNRLEVAADSYlkLRFIQKSI-LKAIDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVA 759
Cdd:PRK12904 710 ldEEELRERILEAAEEAYEEKEEELGEEQ--MREFERVVmLQVLDTKWREHLAAMDHLRQGIGLRGYAQKDPLQEYKREG 787
|
810
....*....|....*....
gi 487751202 760 LETYEYMSEDIKRKMVRNL 778
Cdd:PRK12904 788 FELFEEMLDSIKEEVVRTL 806
|
|
| secA |
TIGR00963 |
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are ... |
24-770 |
0e+00 |
|
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are necessary, comprise the standard prokaryotic protein translocation apparatus. Other, specialized translocation systems also exist but are not as broadly distributed. This model describes SecA, an essential member of the apparatus. This model excludes SecA2 of the accessory secretory system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273366 [Multi-domain] Cd Length: 742 Bit Score: 686.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 24 INALSEEFSNFSDEALQAKTKEFKVYLNDNKASLNHILPQAYATVREASKRVLGMYPKDVQILGAIAMHQGNIAEMQTGE 103
Cdd:TIGR00963 1 INALEEDYEKLSDEELRNKTNEFKDRLAKQGETLDDLLPEAFAVVREASKRVLGMRPFDVQLIGGIALHKGKIAEMKTGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 104 GKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEyeyaeNEKYELYHHDIVYTTNGR 183
Cdd:TIGR00963 81 GKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAEWMGQVYRFLGLSVGLILSGMSP-----EERREAYACDITYGTNNE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 184 LGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLEKDKDFIVNFNKKEV 263
Cdd:TIGR00963 156 LGFDYLRDNMAHSKEEKVQRPFHFAIIDEVDSILIDEARTPLIISGPAEKSTELYVQANKFAKALEKEVDYEVDEKNRAV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 264 WLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLPGTKLQSGLHQAIEA 343
Cdd:TIGR00963 236 LLTEQGMKKAEDLLGVDNLYDLENSPLIHYINNALKAKELFQKDVDYIVRDGEVVIVDEFTGRIMEGRRWSDGLHQAIEA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 344 LENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRPDRVFANGDKKNDAIL 423
Cdd:TIGR00963 316 KEGVEIQNENQTLATITYQNFFRLYEKLSGMTGTAKTEEEEFRKIYNLEVVVVPTNRPVIRKDRPDLVYKTEEEKWKAVV 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 424 KTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVATSMAGRGTDIKLsKEV 503
Cdd:TIGR00963 396 EEIKERHAKGQPVLVGTTSVEKSELLSNLLKERGIPHNVLNAKNHEREAEIIAQAGRKGAVTIATNMAGRGTDIKL-EEV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 504 HDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWSNSNLAE-NKNLQTMDASKLESSaLFKKRV 582
Cdd:TIGR00963 475 KELGGLYVIGTERHESRRIDNQLRGRSGRQGDPGSSRFFLSLEDNLMRIFGGDRLEGlMRRLGMDDDEPIESK-MVSRAL 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 583 KSivnkAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDF---NFEQLARDVFTKDVKNLDLSSE--- 656
Cdd:TIGR00963 554 ES----AQKRVEGRNFDIRKQLLEYDDVLNKQREVIYAERRRVLESEDLSELilqMLESTLDRIVDAYINEEKLSEEwdl 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 657 RALVNYIyeNLSFVFDEDVSNINMQN--DEEIIQFLIQQFTQQFNNRLEVAADSYLKlRFIQKSILKAIDSEWIEQVDNL 734
Cdd:TIGR00963 630 EGLIEKL--KTLFLLDGDLTPEDLENltSEDLKELLLEKIRAAYDEKEEQLESERMR-EFERYVLLQSIDRKWKEHLDAM 706
|
730 740 750
....*....|....*....|....*....|....*.
gi 487751202 735 QQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDI 770
Cdd:TIGR00963 707 DLLREGIGLRSYGQKDPLIEYKNEGFNLFEEMLEDI 742
|
|
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
14-778 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 682.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 14 LRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGAIAMHQ 93
Cdd:COG0653 17 LKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLANGE-TLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGIVLHQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 94 GNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSlgfVDIPEYEYAenEKYELYH 173
Cdd:COG0653 96 GKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLSVG---VIVHGMDPE--ERRAAYA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 174 HDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLEKDKD 253
Cdd:COG0653 171 ADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYYRINKLVPRLKRDGD 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 254 FIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLPGTKL 333
Cdd:COG0653 251 YTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENIELVHHLNQALRAHALFKRDVDYIVKDGEVVIVDEFTGRLMPGRRY 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 334 QSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRPDRVFA 413
Cdd:COG0653 331 SDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYGLDVVVIPTNRPMIRKDEPDLVYK 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 414 NGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVATSMAGR 493
Cdd:COG0653 411 TEEEKFNAVVEDIKERHEKGQPVLVGTTSIEKSELLSKLLKKEGIPHNVLNAKQHEREAEIVAQAGRPGAVTIATNMAGR 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 494 GTDIKL---------------------------------SKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQ 540
Cdd:COG0653 491 GTDIVLggnpeflaaaeladrgleweeaiakikaewqaeHEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSR 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 541 IFVSLDDDLVKRWSNSNLaenKNLqtMDASKL-ESSALFKKRV-KSIvNKAQRVSEEtamKNREM----------ANEfe 608
Cdd:COG0653 571 FYLSLEDDLMRIFGSDRI---KGM--MDKLGMeEGEPIEHKMVsKAI-ENAQKKVEG---RNFDIrknlleyddvMND-- 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 609 ksisvQRDKIYAERNHILEASDFDDfNFEQLARDVFTK---------------DVKNLdlssERALVNYIYENLSFVFDE 673
Cdd:COG0653 640 -----QRKVIYEQRREILEGEDLSE-TILDMREDVIEDlvdeyipegsypeqwDLEGL----EEALKELFGLDLPIEEWL 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 674 DVSNInmqNDEEIIQFLIQQFTQQFNNRLEVAADSYlkLRFIQKSI-LKAIDSEWIEQVDNLQQLKASVNNRQNGQRNVI 752
Cdd:COG0653 710 DEEGL---DEEELRERLLEAADEAYEEKEEELGPEV--MRELERVVlLQVLDRKWREHLDAMDHLRQGIGLRGYAQKDPL 784
|
810 820
....*....|....*....|....*.
gi 487751202 753 FEYHKVALETYEYMSEDIKRKMVRNL 778
Cdd:COG0653 785 VEYKREAFELFEEMLDSIKEEVVRYL 810
|
|
| secA |
PRK12906 |
preprotein translocase subunit SecA; Reviewed |
1-776 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237260 [Multi-domain] Cd Length: 796 Bit Score: 678.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 1 MAKGVNQIINNI--RLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNkASLNHILPQAYATVREASKRVLGM 78
Cdd:PRK12906 1 MANILKKWFDNDkrELKRLEKIADKVNALEDEYEKLSDEQLQAKTPEFRDRIKDG-ESLDDLLPEAFAVAREGAKRVLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 79 YPKDVQILGAIAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDI 158
Cdd:PRK12906 80 RPFDVQIIGGIVLHEGNIAEMKTGEGKTLTATLPVYLNALTGKGVHVVTVNEYLSSRDATEMGELYRWLGLTVGLNLNSM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 159 -PEyeyaenEKYELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNL 237
Cdd:PRK12906 160 sPD------EKRAAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKATDL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 238 FHIVKTFVETLEKDK-----------DFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKY 306
Cdd:PRK12906 234 YIRADRFVKTLIKDEaedgdddedtgDYKIDEKTKTISLTEQGIRKAEKLFGLDNLYDSENTALAHHIDQALRANYIMLK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 307 NLDYFIFDGEIVLIDRITGRMLPGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFF 386
Cdd:PRK12906 314 DIDYVVQDGEVLIVDEFTGRVMEGRRYSDGLHQAIEAKEGVKIQEENQTLATITYQNFFRMYKKLSGMTGTAKTEEEEFR 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 387 DLYSKVVIEIPTHSPIERDDRPDRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQ 466
Cdd:PRK12906 394 EIYNMEVITIPTNRPVIRKDSPDLLYPTLDSKFNAVVKEIKERHAKGQPVLVGTVAIESSERLSHLLDEAGIPHAVLNAK 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 467 NVAKEAQMIAEAGQLSAVTVATSMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLD 546
Cdd:PRK12906 474 NHAKEAEIIMNAGQRGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 547 DDLVKRWSNsnlaeNKNLQTMDASKL--ESSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNH 624
Cdd:PRK12906 554 DDLMRRFGS-----DRVKAFLDRLGMndDDQVIESRMITRQVESAQKRVEGNNYDTRKQLLQYDDVMREQREVIYKQRMQ 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 625 IL-EASDFDDFNFEQLARDV-------FTKDVKNLDLSserALVNYIYENLSFVFDEDVSNINMQNDEEIIQFLIQQFTQ 696
Cdd:PRK12906 629 VInEDKDLKEVLMPMIKRTVdrqvqmyTQGDKKDWDLD---ALRDFIVSAMPDEETFDFEDLKGKSPEELKKRLLDIVED 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 697 QFNNRLEVAADSYLKLRFIQKSILKAIDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMVR 776
Cdd:PRK12906 706 NYAEKEKQLGDPTQMLEFEKVVILRVVDSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQEEGYRMFEEMISNIDYDVTR 785
|
|
| secA |
PRK12903 |
preprotein translocase subunit SecA; Reviewed |
14-779 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237258 [Multi-domain] Cd Length: 925 Bit Score: 639.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 14 LRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGAIAMHQ 93
Cdd:PRK12903 14 MRIAEKILKQINDLEPYYRNLTDEELANKTNEFKDRLKNGE-TLEDIRVEAFAVAREATKRVLGKRPYDVQIIGGIILDL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 94 GNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEyeyaeNEKYELYH 173
Cdd:PRK12903 93 GSVAEMKTGEGKTITSIAPVYLNALTGKGVIVSTVNEYLAERDAEEMGKVFNFLGLSVGINKANMDP-----NLKREAYA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 174 HDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLeKDKD 253
Cdd:PRK12903 168 CDITYSVHSELGFDYLRDNMVSSKEEKVQRGLNFCLIDEVDSILIDEAKTPLIISGGQSNDSNLYLAADQFVRTL-KEDD 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 254 FIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLPGTKL 333
Cdd:PRK12903 247 YKIDEETKAISLTEKGIKKANKFFKLKNLYDIENSELVHRIQNALRAHKVMKEDVEYIVRDGKIELVDQFTGRIMEGRSY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 334 QSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRPDRVFA 413
Cdd:PRK12903 327 SEGLQQAIQAKEMVEIEPETKTLATITYQNFFRLFKKLSGMTGTAKTEEQEFIDIYNMRVNVVPTNKPVIRKDEPDSIFG 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 414 NGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVATSMAGR 493
Cdd:PRK12903 407 TKHAKWKAVVKEVKRVHKKGQPILIGTAQVEDSETLHELLLEANIPHTVLNAKQNAREAEIIAKAGQKGAITIATNMAGR 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 494 GTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWSNSNLAENKnlqtmdASKLE 573
Cdd:PRK12903 487 GTDIKLSKEVLELGGLYVLGTDKAESRRIDNQLRGRSGRQGDVGESRFFISLDDQLFRRFSNFDKIKEA------FKKLG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 574 SSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDFNFEQLARDV-----FTKDV 648
Cdd:PRK12903 561 DDEIKSKFFSKALLNAQKKIEGFNFDTRKNVLDYDDVIRQQRDLIYAQRDLILIADDLSHVIEKMISRAVeqilkNSFII 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 649 KNLDLSSERALVNYIYENLSFVFDEDVSNINMQN--DEEIIQFLIQQFTQQFNNRLEVAADSYLKLRFIQ---KSILKAI 723
Cdd:PRK12903 641 LKNNTINYKELVEFLNDNLLRITHFKFSEKDFENyhKEELAQYLIEALNEIYFKKRQVILDKIALNTFFEserYIILSAL 720
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 487751202 724 DSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMVRNLC 779
Cdd:PRK12903 721 DKYWQNHIDTMDKLRSGVNLVQYSQKNPYQVYTEEGTKKFNILLQEIAYDVIVSLF 776
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
10-386 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 570.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 10 NNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGAI 89
Cdd:smart00957 9 NDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAEGE-SLDDLLPEAFAVVREAAKRVLGMRHFDVQLIGGI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 90 AMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEyeyaeNEKY 169
Cdd:smart00957 88 VLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIVSGMSP-----EERR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 170 ELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISG-APRVQSNLFHIVKTFVETL 248
Cdd:smart00957 163 AAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGpAEDESSDLYHRADKFVPRL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 249 EKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRML 328
Cdd:smart00957 243 KEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPENIELLHHVNQALRAHYLFKRDVDYIVRDGEVVIVDEFTGRVM 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 487751202 329 PGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFF 386
Cdd:smart00957 323 EGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMYKKLSGMTGTAKTEAEEFR 380
|
|
| secA |
CHL00122 |
preprotein translocase subunit SecA; Validated |
9-778 |
0e+00 |
|
preprotein translocase subunit SecA; Validated
Pssm-ID: 214371 [Multi-domain] Cd Length: 870 Bit Score: 570.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 9 INNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGA 88
Cdd:CHL00122 7 NNKSKLNKYQTLVNQINLLEEELKNLTDTELRSKTNKLKKRLSNGQ-NLNKIIPESFALTREASFRTLGLRHFDVQLIGG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 89 IAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLgfvdIPEYEYAEnEK 168
Cdd:CHL00122 86 LVLNDGKIAEMKTGEGKTLVATLPAYLNALTGKGVHIVTVNDYLAKRDQEWMGQIYRFLGLTVGL----IQEGMSSE-ER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 169 YELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETL 248
Cdd:CHL00122 161 KKNYLKDITYVTNSELGFDYLRDNMALSLSDVVQRPFNYCIIDEVDSILIDEARTPLIISGQSKTNIDKYIVADELAKYL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 249 EKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHlSLRAKYLFKYNLDYFIFDGEIVLIDRITGRML 328
Cdd:CHL00122 241 EKNVHYEVDEKNKNVILTEQGILFIEKILKIEDLYSANDPWIPYILN-ALKAKELFFKNVHYIVRNNEIIIVDEFTGRIM 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 329 PGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRP 408
Cdd:CHL00122 320 PGRRWSDGLHQAIEAKENLPIRQETETLASITYQNFFLLYPKLSGMTGTAKTEELEFEKIYNLEVVCIPTHRPMLRKDLP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 409 DRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIA--QNVAKEAQMIAEAGQLSAVTV 486
Cdd:CHL00122 400 DLIYKDELSKWRAIADECLQMHQTGRPILIGTTTIEKSELLSQLLKEYRLPHQLLNAkpENVRRESEIVAQAGRKGSITI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 487 ATSMAGRGTDIKL------------------------------------------------------------------- 499
Cdd:CHL00122 480 ATNMAGRGTDIILggnpefklkkelydlllsyksnekistisqnflnilnslkndlkflslsdfenlkilneaseisipk 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 500 -------------------------SKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWS 554
Cdd:CHL00122 560 nsyqlslrflynellekykklqekeKKIVKKLGGLYVIGTERHESRRIDNQLRGRAGRQGDPGSSRFFLSLEDNLLRIFG 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 555 NSNLAENKNLQTMDASKLESSALFKkrvksIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDF 634
Cdd:CHL00122 640 GDKIQNLMQTLNLDDEPLESKLLSK-----SLDSAQKKVEEYYYDQRKQLFEYDQVLNKQRKAIYSERRKILESQSLRDW 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 635 NF---EQLARDVFTK-DVKNLDLSSERALVNYIYENLSFVFDEDVSNINMQNDEEIIQFLIQQFTQQFN---NRLEVAAD 707
Cdd:CHL00122 715 ILaygEQVIDDIITFlKSRKNPNNKFINLINKFKELLKLPLCFNKSDLNTLNSGELKKFLYQQFWISYDlkeLYLEQIGT 794
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487751202 708 SYlkLRFIQKS-ILKAIDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMVRNL 778
Cdd:CHL00122 795 GL--MRELERSlLLQQIDKSWKEHLQKMSLLREAIGWRSYGQKDPLIEYKNEAFNLFINMINHIRHLVIYDL 864
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
10-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 532.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 10 NNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKaSLNHILPQAYATVREASKRVLGMYPKDVQILGAI 89
Cdd:pfam07517 9 NERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERLREGE-SLDDILPEAFALVREAAKRVLGMRHYDVQLIGGL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 90 AMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEyeyaeNEKY 169
Cdd:pfam07517 88 VLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVITSDMDP-----EERR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 170 ELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLE 249
Cdd:pfam07517 163 AAYNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYREADRLVKSLE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 250 KDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLP 329
Cdd:pfam07517 243 EDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENVELLHHINQALKAHHLFKRDVDYIVRDGEVVIVDEFTGRVMP 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 487751202 330 GTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEF 385
Cdd:pfam07517 323 GRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLYPKLSGMTGTAKTEAEEF 378
|
|
| secA |
PRK12898 |
preprotein translocase subunit SecA; Reviewed |
9-601 |
8.17e-176 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237253 [Multi-domain] Cd Length: 656 Bit Score: 520.34 E-value: 8.17e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 9 INNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKASLNHILPQAYATVREASKRVLGMYPKDVQILGA 88
Cdd:PRK12898 33 VRGRAARRQRLLADRVLAAAEALAGLSEEALRARSLALRARLRARDGFRDALLAEAFALVREASGRVLGQRHFDVQLMGG 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 89 IAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGfvdIPEYEYAENEK 168
Cdd:PRK12898 113 LALLSGRLAEMQTGEGKTLTATLPAGTAALAGLPVHVITVNDYLAERDAELMRPLYEALGLTVGCV---VEDQSPDERRA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 169 yeLYHHDIVYTTNGRLGFDYLIDNL-----ADDIRAKF--------------LPKLNFAIIDEVDSIILDAAQTPLVISG 229
Cdd:PRK12898 190 --AYGADITYCTNKELVFDYLRDRLalgqrASDARLALeslhgrssrstqllLRGLHFAIVDEADSVLIDEARTPLIISA 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 230 APRVQSNL--FHIVKTFVETLEKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYN 307
Cdd:PRK12898 268 PAKEADEAevYRQALELAAQLKEGEDYTIDAAEKRIELTEAGRARIAELAESLPPAWRGAVRREELVRQALSALHLFRRD 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 308 LDYFIFDGEIVLIDRITGRMLPGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFD 387
Cdd:PRK12898 348 EHYIVRDGKVVIVDEFTGRVMPDRSWEDGLHQMIEAKEGCELTDPRETLARITYQRFFRRYLRLAGMTGTAREVAGELWS 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 388 LYSKVVIEIPTHSPIERDDRPDRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQN 467
Cdd:PRK12898 428 VYGLPVVRIPTNRPSQRRHLPDEVFLTAAAKWAAVAARVRELHAQGRPVLVGTRSVAASERLSALLREAGLPHQVLNAKQ 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 468 VAKEAQMIAEAGQLSAVTVATSMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDD 547
Cdd:PRK12898 508 DAEEAAIVARAGQRGRITVATNMAGRGTDIKLEPGVAARGGLHVILTERHDSARIDRQLAGRCGRQGDPGSYEAILSLED 587
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 487751202 548 DLVKRWSNSNLaenknLQTMDASKLESSAlFKKRVKSIVNKAQRVSEETAMKNR 601
Cdd:PRK12898 588 DLLQSFLGSRG-----LAIRRMELLGPRG-GRALGALLLRRAQRRAERLHARAR 635
|
|
| secA |
PRK12901 |
preprotein translocase subunit SecA; Reviewed |
14-775 |
8.44e-154 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237256 [Multi-domain] Cd Length: 1112 Bit Score: 477.59 E-value: 8.44e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 14 LRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKAS------------------------------------- 56
Cdd:PRK12901 17 LKEIQPIVEKIKAEYPELEALSNDELRAKTDEFKQYIKEAVADidakieelkaeaiesldiderediyaqidklekeaye 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 57 -----LNHILPQAYATVREASKRVLG---------------------------------------------MYPKDVQIL 86
Cdd:PRK12901 97 ilekvLDEILPEAFAIVKETARRFAEneeievtatdfdrelaatkdfvtiegdkaiwknhwdaggneitwdMVHYDVQLI 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 87 GAIAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLgfvdIPEYEYAEN 166
Cdd:PRK12901 177 GGVVLHQGKIAEMATGEGKTLVATLPVYLNALTGNGVHVVTVNDYLAKRDSEWMGPLYEFHGLSVDC----IDKHQPNSE 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 167 EKYELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGA-------------PRV 233
Cdd:PRK12901 253 ARRKAYNADITYGTNNEFGFDYLRDNMAHSPEDLVQRKHNYAIVDEVDSVLIDDARTPLIISGPvpkgddqefeelkPRV 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 234 QsNLFHIVKTFVETLEKD-KDFIVNFNKKEV-------------------WLTDEGSEKASHyfKVNSIYQQQ------- 286
Cdd:PRK12901 333 E-RLVEAQRKLATQFLAEaKKLIAEGDKKEGglallrayrglpknkalikFLSEEGIKALLQ--KTENFYMQDnnrempe 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 287 -----YF---------DL----------------------------------------------------------VRMI 294
Cdd:PRK12901 410 vdeelYFvideknnsvELtdkgidyitgndedpdffvlpdigtelaeieneggldeeeeaekkeelfqdysvkserVHTL 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 295 HLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLPGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGM 374
Cdd:PRK12901 490 NQLLKAYTLFEKDDEYVVMDGKVKIVDEQTGRIMEGRRYSDGLHQAIEAKENVKIEAATQTFATITLQNYFRMYHKLAGM 569
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 375 TGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRPDRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELF 454
Cdd:PRK12901 570 TGTAETEAGEFWDIYKLDVVVIPTNRPIARKDKEDLVYKTKREKYNAVIEEITELSEAGRPVLVGTTSVEISELLSRMLK 649
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 455 KRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVATSMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQG 534
Cdd:PRK12901 650 MRKIPHNVLNAKLHQKEAEIVAEAGQPGTVTIATNMAGRGTDIKLSPEVKAAGGLAIIGTERHESRRVDRQLRGRAGRQG 729
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 535 DPGYSQIFVSLDDDLVKRWSNSNLAenknlQTMDASKLESSALFKKRV--KSIvNKAQRVSEETAMKNREMANEFEKSIS 612
Cdd:PRK12901 730 DPGSSQFYVSLEDNLMRLFGSERIA-----KVMDRMGLKEGEVIQHSMisKSI-ERAQKKVEENNFGIRKRLLEYDDVMN 803
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 613 VQRDKIYAERNHIL-------------------------EASDFDDFNFEQLARDVFTKDVknldlsSERALVNYIYENL 667
Cdd:PRK12901 804 SQREVIYKRRRHALmgerlgmdianmiydvceaivennkVANDYKGFKFELIRTLAMESPI------TEEEFNKLKKDEL 877
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 668 SF-VFDEDVSNIN--MQNDEEIIQFLIQQFTQQFNNR--------------------LEVAADSYLK--LRFIQKSILKA 722
Cdd:PRK12901 878 TDkLYDAALENYQrkMERIAEIAFPVIKQVYEEQGNMyerivvpftdgkrtlnvvtnLKEAYETEGKeiVKDFEKNITLH 957
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....
gi 487751202 723 -IDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMV 775
Cdd:PRK12901 958 iIDEAWKEHLREMDELKQSVQNASYEQKDPLLIYKFESFELFKNMVDKVNREVI 1011
|
|
| SecA2_Mycobac |
TIGR04221 |
accessory Sec system translocase SecA2, Actinobacterial type; Members of this family are the ... |
14-775 |
1.47e-138 |
|
accessory Sec system translocase SecA2, Actinobacterial type; Members of this family are the SecA2 subunit of the Mycobacterial type of accessory secretory system. This family is quite different SecA2 of the Staph/Strep type (TIGR03714).
Pssm-ID: 275062 [Multi-domain] Cd Length: 762 Bit Score: 427.71 E-value: 1.47e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 14 LRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKAslnhilPQAYATVREASKRVLGMYPKDVQILGAIAMHQ 93
Cdd:TIGR04221 17 QKRSLAIVPAAASRMKELSALDDEELTKAARDLVLSGEAADA------AQFLAILREAAERTLGMRPFDVQLLGALRLLA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 94 GNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVslGFVDipeYEYAENEKYELYH 173
Cdd:TIGR04221 91 GDVIEMATGEGKTLAGAMAATGFALLGKRVHVVTVNDYLARRDAEWMGPLVDFFGLTV--GWVT---EDSTPDERRAAYA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 174 HDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGA-PRVQSNlfHIVKTFVETLEKDK 252
Cdd:TIGR04221 166 CDVTYASVNEIGFDVLRDQLVTDRADLVQPAADVALIDEADSVLVDEALVPLVLAGNePGEAPR--GRITDLVRRLREDK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 253 DFIVNFNKKEVWLTDEGSEKASHYFKVNSIY-QQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLPGT 331
Cdd:TIGR04221 244 HYTVDEDGRNVHLTEDGARAVEAELGIDDLYsEEHVGTTLVQVNVALHAHALLIRDVHYIVRDGKVALIDASRGRVAQLQ 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 332 KLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKL-GE--KEFFDLYSKVvieIPTHSPIERDDRP 408
Cdd:TIGR04221 324 RWPDGLQAAVEAKEGLEVTEGGEVLDTITVQALIGRYPTVCGMTGTAVAaGEqlRQFYDLGVSV---IPPNTPNIRFDEA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 409 DRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVAT 488
Cdd:TIGR04221 401 DRVYATAAEKNDAIVEEIAEVHKTGQPVLVGTQDVAESEELAEALLEAGVPCNVLNAKNDAEEAAIIAEAGDIGAVTVST 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 489 SMAGRGTDIKLS-------KEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRwsnsNLAEN 561
Cdd:TIGR04221 481 QMAGRGTDIRLGgsdeadhDRVAELGGLHVIGTGRHRTARLDNQLRGRAGRQGDPGSSVFFVSLEDDVVAV----GGAGE 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 562 knlqTMDASKLESSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEAsdfdDFNFEQLAr 641
Cdd:TIGR04221 557 ----TVPAQPAEDGRIESPRVQDFVDHAQRVAEGQLLEIHANTWRYNQLIAQQRDIIDERRETLLDT----DTAWQELS- 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 642 dvftkdvknlDLSSERalvnyiYENLSFVFDEDvsninmqndeeiiqfliqqftqqfnnRLEVAAdsylklRFIqksILK 721
Cdd:TIGR04221 628 ----------ERAADR------AAELKKEVSED--------------------------ALERAA------REI---MLY 656
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....
gi 487751202 722 AIDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMV 775
Cdd:TIGR04221 657 HLDRGWAEHLAYLDDVRESIHLRALGRETPLDEFHRMAVRAFKELAQRAVDKAV 710
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
38-398 |
1.71e-92 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 289.05 E-value: 1.71e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 38 ALQAKTKEFKVYLnDNKASLNHILPQAYATVREASKRVLGMYPKDVQILGAIAMHQGNIAEMQTGEGKTLTATMPLYLNA 117
Cdd:cd17928 1 ELRAKTDELRERL-AKGETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 118 LTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDipeyeYAENEKYELYHHDIVYTTNGRLGFDYLIDNLADDI 197
Cdd:cd17928 80 LTGKGVHVVTVNDYLARRDAEWMGPLYEFLGLTVGVILSD-----MSPDERREAYAADITYGTNNELGFDYLRDNMVTSK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 198 RAKFLPKLNFAIIDEVDSIILDAAQTPLVISGaprvqsnlfhivktfvetlekdkdfivnfnkkevwltdegsekashyf 277
Cdd:cd17928 155 EDLVQRGLNFAIVDEVDSILIDEARTPLIISG------------------------------------------------ 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 278 kvnsiyqqqyfdlvrmihlslrakylfkynldyfifdgeivlidritgrmlpgtklqsglhqaiealenveisqdmsVMA 357
Cdd:cd17928 187 -----------------------------------------------------------------------------TLA 189
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 487751202 358 TITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPT 398
Cdd:cd17928 190 TITFQNYFRLYPKLAGMTGTAKTEAEEFREIYNLDVVVIPT 230
|
|
| SF2_C_secA |
cd18803 |
C-terminal helicase domain of the protein translocase subunit secA; SecA is a component of the ... |
404-544 |
1.36e-65 |
|
C-terminal helicase domain of the protein translocase subunit secA; SecA is a component of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA is a DEAD-like helicase belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350190 [Multi-domain] Cd Length: 141 Bit Score: 214.34 E-value: 1.36e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 404 RDDRPDRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSA 483
Cdd:cd18803 1 RKDLPDLVYKTEEEKWKAIVEEVKELHAKGQPVLVGTRSVEKSELLSALLKEEGIPHNVLNAKNHAREAEIIAEAGQKGA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 487751202 484 VTVATSMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVS 544
Cdd:cd18803 81 VTIATNMAGRGTDIKLGGNVEELGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLS 141
|
|
| SecA_PP_bind |
smart00958 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
230-342 |
2.14e-37 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 214938 [Multi-domain] Cd Length: 114 Bit Score: 135.66 E-value: 2.14e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 230 APRVQSNLFHIVKTFVETLEKD-KDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNL 308
Cdd:smart00958 1 PAEDSSELYKRADELVPTLKKDeEDYEVDEKSRQVALTEEGIEKAEKLLGIDNLYDPENIELVHHVNQALRAHKLFKRDV 80
|
90 100 110
....*....|....*....|....*....|....
gi 487751202 309 DYFIFDGEIVLIDRITGRMLPGTKLQSGLHQAIE 342
Cdd:smart00958 81 DYIVRDGEVVIVDEFTGRVMPGRRWSDGLHQAIE 114
|
|
| SecA_PP_bind |
pfam01043 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
233-342 |
9.92e-36 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 460039 [Multi-domain] Cd Length: 110 Bit Score: 130.61 E-value: 9.92e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 233 VQSNLFHIVKTFVETLEKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFI 312
Cdd:pfam01043 1 KSTELYRQADKFVKQLKEDEDYEVDEKAKTVELTEEGIEKAEKLLGIDNLYDPENIELVHHINQALKAHHLFKRDVDYIV 80
|
90 100 110
....*....|....*....|....*....|
gi 487751202 313 FDGEIVLIDRITGRMLPGTKLQSGLHQAIE 342
Cdd:pfam01043 81 KDGEVVIVDEFTGRLMPGRRYSDGLHQAIE 110
|
|
| SecA_SW |
pfam07516 |
SecA Wing and Scaffold domain; SecA protein binds to the plasma membrane where it interacts ... |
580-779 |
4.16e-29 |
|
SecA Wing and Scaffold domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This family is composed of two C-terminal alpha helical subdomains: the wing and scaffold subdomains.
Pssm-ID: 462189 [Multi-domain] Cd Length: 213 Bit Score: 115.28 E-value: 4.16e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 580 KRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDfNFEQLARDVFTKDVKNLDLSSERA- 658
Cdd:pfam07516 5 KMVSKAIENAQKKVEGRNFDIRKNLLEYDDVMNQQREVIYAQRREILEGEDLKE-DILEMIEDVVDDIVDEYIPPEESPe 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 659 ------LVNYIYENLSFVFDE-DVSNINMQNDEEIIQFLIQQFTQQFNNRLEVAADSYLklRFIQKSI-LKAIDSEWIEQ 730
Cdd:pfam07516 84 ewdlegLKEALNEIFGLELPIsEWEEEEDLDKEELKERLLEAAEEAYEEKEEEIGPELM--RELERVVlLQVIDSKWKEH 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 487751202 731 VDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMVRNLC 779
Cdd:pfam07516 162 LDAMDQLRQGIGLRAYGQKDPLVEYKREGFELFEEMLDAIREEVVRYLF 210
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
96-226 |
1.10e-13 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 68.97 E-value: 1.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 96 IAEMQTGEGKTLTATMPLYLNALT-GKGAYLITTNDYLAKRDFLEMKPLYEWlGLSVSlgfVDIPEYEYAENEKYELYHH 174
Cdd:cd00046 5 LITAPTGSGKTLAALLAALLLLLKkGKKVLVLVPTKALALQTAERLRELFGP-GIRVA---VLVGGSSAEEREKNKLGDA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 487751202 175 DIVYTTNGRLGFDYLIDNLAddirakFLPKLNFAIIDEVDSIILDAAQTPLV 226
Cdd:cd00046 81 DIIIATPDMLLNLLLREDRL------FLKDLKLIIVDEAHALLIDSRGALIL 126
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
96-136 |
8.00e-06 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 44.43 E-value: 8.00e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 487751202 96 IAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRD 136
Cdd:cd17912 3 LHLGPTGSGKTLVAIQKIASAMSSGKSVLVVTPTKLLAHEI 43
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
80-217 |
1.93e-05 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 46.33 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 80 PKDVQILGAIAMHQGN---IAEMQTGEGKTLTATMPL--YLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLG 154
Cdd:smart00487 9 LRPYQKEAIEALLSGLrdvILAAPTGSGKTLAALLPAleALKRGKGGRVLVLVPTRELAEQWAEELKKLGPSLGLKVVGL 88
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 487751202 155 FVDIPEYEyaENEKYELYHHDIVYTTNGRLgFDYLIDNladdirAKFLPKLNFAIIDEVDSII 217
Cdd:smart00487 89 YGGDSKRE--QLRKLESGKTDILVTTPGRL-LDLLEND------KLSLSNVDLVILDEAHRLL 142
|
|
| DEAD-like_helicase_C |
cd09300 |
C-terminal helicase domain of the DEAD-like helicases; This hierarchy of DEAD-like helicases ... |
484-543 |
5.67e-04 |
|
C-terminal helicase domain of the DEAD-like helicases; This hierarchy of DEAD-like helicases is composed of two superfamilies, SF1 and SF2, that share almost identical folds and extensive structural similarity in their catalytic core. Helicases are involved in ATP-dependent RNA or DNA unwinding. Two distinct types of helicases exist, those forming toroidal, predominantly hexameric structures, and those that do not. SF1 and SF2 helicases do not form toroidal structures, while SF3-6 helicases do. Their conserved helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350171 [Multi-domain] Cd Length: 59 Bit Score: 38.68 E-value: 5.67e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 484 VTVATSMAGRGTDIKlskevhdiGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFV 543
Cdd:cd09300 8 VLIAVN*ALTGFDAP--------ELNTIIVDKNLRSYRGLNQAFGRANRIYTFGGIVTYR 59
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
96-214 |
1.36e-03 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 40.30 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 96 IAEMQTGEGKTLTATMPLYLNALTGKGAYLI-----TTNdyLAKRDFLEMKPLYEWLGLSVSLGFVDIPEYEyaenEKYE 170
Cdd:pfam00270 18 LVQAPTGSGKTLAFLLPALEALDKLDNGPQAlvlapTRE--LAEQIYEELKKLGKGLGLKVASLLGGDSRKE----QLEK 91
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 487751202 171 LYHHDIVYTTNGRLgFDYLidnladdIRAKFLPKLNFAIIDEVD 214
Cdd:pfam00270 92 LKGPDILVGTPGRL-LDLL-------QERKLLKNLKLLVLDEAH 127
|
|
| DEXHc_archSki2 |
cd18028 |
DEXH-box helicase domain of archaeal Ski2-type helicase; Archaeal Ski2-type RNA helicases play ... |
96-216 |
4.65e-03 |
|
DEXH-box helicase domain of archaeal Ski2-type helicase; Archaeal Ski2-type RNA helicases play an important role in RNA degradation, processing and splicing pathways. They belong to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350786 [Multi-domain] Cd Length: 177 Bit Score: 38.85 E-value: 4.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487751202 96 IAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEwLGLSVSLGFVDipeyeYAENEKYeLYHHD 175
Cdd:cd18028 21 LISIPTASGKTLIAEMAMVNTLLEGGKALYLVPLRALASEKYEEFKKLEE-IGLKVGISTGD-----YDEDDEW-LGDYD 93
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 487751202 176 IVYTTNGRlgFDYLIDNLADDIRAkflpkLNFAIIDEVDSI 216
Cdd:cd18028 94 IIVATYEK--FDSLLRHSPSWLRD-----VGVVVVDEIHLI 127
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|
| |
