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Conserved domains on  [gi|487833139|ref|WP_001906605|]
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MULTISPECIES: DeoR/GlpR family DNA-binding transcription regulator [Vibrio]

Protein Classification

DeoR/GlpR family DNA-binding transcription regulator( domain architecture ID 11442564)

DeoR/GlpR family DNA-binding transcription regulator is a helix-turn-helix type transcriptional regulator that may be involved in sugar metabolism

Gene Ontology:  GO:0003700|GO:0003677
PubMed:  15808743

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 5-253 1.11e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


:

Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 273.16  E-value: 1.11e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   5 NTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEVMHDELNEKVSVR---KIS 81
Cdd:COG1349    2 LAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNaeeKRA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  82 LAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENePTLLMTGGTWDTHSESFQGKVAESV 161
Cdd:COG1349   82 IARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPN-IEVILLGGELRPSSGSLVGPLAEEA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 162 LRSYDFDQLFIGADGIDLDRGTTTFNEL-VGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSDEFA 240
Cdd:COG1349  161 LRRFRADKAFLGASGIDAEGGLTTFDEEeAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELL 240

                        250
                 ....*....|...
gi 487833139 241 KQIESHQVRVIRA 253
Cdd:COG1349  241 EALEEAGVEVIVA 253
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 5-253 1.11e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 273.16  E-value: 1.11e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   5 NTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEVMHDELNEKVSVR---KIS 81
Cdd:COG1349    2 LAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNaeeKRA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  82 LAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENePTLLMTGGTWDTHSESFQGKVAESV 161
Cdd:COG1349   82 IARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPN-IEVILLGGELRPSSGSLVGPLAEEA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 162 LRSYDFDQLFIGADGIDLDRGTTTFNEL-VGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSDEFA 240
Cdd:COG1349  161 LRRFRADKAFLGASGIDAEGGLTTFDEEeAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELL 240

                        250
                 ....*....|...
gi 487833139 241 KQIESHQVRVIRA 253
Cdd:COG1349  241 EALEEAGVEVIVA 253
srlR PRK10434
DNA-binding transcriptional repressor;
7-251 1.92e-81

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 244.98  E-value: 1.92e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   7 QLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIaLPKEVMHDELNEKVSV---RKISLA 83
Cdd:PRK10434   4 RQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVV-LNKEESDPPIDHKTLInthKKELIA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  84 KAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENEPTLLMTGGTWDTHSESFQGKVAESVLR 163
Cdd:PRK10434  83 EAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENAFE 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 164 SYDFDQLFIGADGIDLDRGTTTFNELVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSDEFAKQI 243
Cdd:PRK10434 163 HFTFDKLFIGTDGIDLNAGVTTFNEVYTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAFRQAL 242


                 ....*...
gi 487833139 244 ESHQVRVI 251
Cdd:PRK10434 243 EEKGIEVI 250
AgaR NF040755
transcriptional repressor AgaR;
5-253 8.30e-67

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 207.51  E-value: 8.30e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   5 NTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAI------ALPKEVMHDELNEKVSVr 78
Cdd:NF040755   3 GTSERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALindgfiPGAEPSVEDKSRLNTAV- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  79 KISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENePTLLMTGGTWDTHSESFQGKVA 158
Cdd:NF040755  82 KRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEG-VEVLMTGGHLRRQSLSFYGDQA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 159 ESVLRSYDFDQLFIGADGIDLDRGTTTFNE-LVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSD 237
Cdd:NF040755 161 EQSLQNYHFDKLFLGVDGFDLERGITTHNEdEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPE 240

                        250
                 ....*....|....*.
gi 487833139 238 EFAKQIESHQVRVIRA 253
Cdd:NF040755 241 EYLQGLRKLGVEVILV 256
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 79-233 7.25e-59

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 183.87  E-value: 7.25e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   79 KISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENePTLLMTGGTWDTHSESFQGKVA 158
Cdd:pfam00455   6 KRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPD-IEVILLGGEVRPKTGAFVGPLA 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487833139  159 ESVLRSYDFDQLFIGADGIDLDRGTTTFNEL-VGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDH 233
Cdd:pfam00455  85 EEFLRQFNVDKAFIGANGIDLEGGLTTSDEEeAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
9-60 4.61e-11

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 56.85  E-value: 4.61e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 487833139     9 RRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAI 60
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAV 52
 
Name Accession Description Interval E-value
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 5-253 1.11e-92

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 273.16  E-value: 1.11e-92
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   5 NTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEVMHDELNEKVSVR---KIS 81
Cdd:COG1349    2 LAEERRQKILELLRERGRVSVEELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPFAERETLNaeeKRA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  82 LAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENePTLLMTGGTWDTHSESFQGKVAESV 161
Cdd:COG1349   82 IARAAASLIEDGDTIFLDAGTTTLALARALPDRRNLTVVTNSLNIANELAERPN-IEVILLGGELRPSSGSLVGPLAEEA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 162 LRSYDFDQLFIGADGIDLDRGTTTFNEL-VGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSDEFA 240
Cdd:COG1349  161 LRRFRADKAFLGASGIDAEGGLTTFDEEeAEVKRAMIEAARRVILLADSSKFGRRALARVAPLSEIDVLITDAGPPPELL 240

                        250
                 ....*....|...
gi 487833139 241 KQIESHQVRVIRA 253
Cdd:COG1349  241 EALEEAGVEVIVA 253
srlR PRK10434
DNA-binding transcriptional repressor;
7-251 1.92e-81

DNA-binding transcriptional repressor;


Pssm-ID: 182457 [Multi-domain]  Cd Length: 256  Bit Score: 244.98  E-value: 1.92e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   7 QLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIaLPKEVMHDELNEKVSV---RKISLA 83
Cdd:PRK10434   4 RQRQAAILEYLQKQGKTSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVV-LNKEESDPPIDHKTLInthKKELIA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  84 KAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENEPTLLMTGGTWDTHSESFQGKVAESVLR 163
Cdd:PRK10434  83 EAAVSLIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENAFE 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 164 SYDFDQLFIGADGIDLDRGTTTFNELVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSDEFAKQI 243
Cdd:PRK10434 163 HFTFDKLFIGTDGIDLNAGVTTFNEVYTVSKAMCNAAREIILMADSSKFGRKSPNVVCSLEKVDKLITDAGIDPAFRQAL 242


                 ....*...
gi 487833139 244 ESHQVRVI 251
Cdd:PRK10434 243 EEKGIEVI 250
AgaR NF040755
transcriptional repressor AgaR;
5-253 8.30e-67

transcriptional repressor AgaR;


Pssm-ID: 468715 [Multi-domain]  Cd Length: 256  Bit Score: 207.51  E-value: 8.30e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   5 NTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAI------ALPKEVMHDELNEKVSVr 78
Cdd:NF040755   3 GTSERREQIIQRLRQQGSVQVEDLSALFGVSTVTIRNDLAFLEKQGIAVRAYGGALindgfiPGAEPSVEDKSRLNTAV- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  79 KISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENePTLLMTGGTWDTHSESFQGKVA 158
Cdd:NF040755  82 KRLIAAAAAELIKPGDRVILDSGTTTYEIARHLKQHQDVVVMTNGLNVANELLEAEG-VEVLMTGGHLRRQSLSFYGDQA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 159 ESVLRSYDFDQLFIGADGIDLDRGTTTFNE-LVGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSD 237
Cdd:NF040755 161 EQSLQNYHFDKLFLGVDGFDLERGITTHNEdEARLNRRMCEVAERIIAVTDSSKFGRSSLHKIRDTGRIDTLITDSGIPE 240

                        250
                 ....*....|....*.
gi 487833139 238 EFAKQIESHQVRVIRA 253
Cdd:NF040755 241 EYLQGLRKLGVEVILV 256
DeoRC pfam00455
DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive ...
 79-233 7.25e-59

DeoR C terminal sensor domain; The sensor domains of the DeoR are catalytically inactive versions of the ISOCOT fold, but retain the substrate binding site. DeorC senses diverse sugar derivatives such as deoxyribose nucleoside (DeoR), tagatose phosphate (LacR), galactosamine (AgaR), myo-inositol (Bacillus IolR) and L-ascorbate (UlaR). It can also bind L-ascorbate 6-phosphate, agrocinopines, sn-glycerol 3-phosphate, and sulfoquinovose (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 395365  Cd Length: 160  Bit Score: 183.87  E-value: 7.25e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   79 KISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENePTLLMTGGTWDTHSESFQGKVA 158
Cdd:pfam00455   6 KRRIAKAAASLIEDGDTIFLDAGTTTLELARALPDRRNLTVITNSLNIANELSEKPD-IEVILLGGEVRPKTGAFVGPLA 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487833139  159 ESVLRSYDFDQLFIGADGIDLDRGTTTFNEL-VGLSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDH 233
Cdd:pfam00455  85 EEFLRQFNVDKAFIGANGIDLEGGLTTSDEEeAEVKRAMIEAARRVILLADSSKFGKRAFARFAPLEDIDALITDK 160
PRK09802 PRK09802
DeoR family transcriptional regulator;
4-238 3.80e-52

DeoR family transcriptional regulator;


Pssm-ID: 182086 [Multi-domain]  Cd Length: 269  Bit Score: 170.42  E-value: 3.80e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   4 RNTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEV--MHDELNEKVSVR--- 78
Cdd:PRK09802  13 TGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTpsVEPSVEDKSALNtam 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  79 KISLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENePTLLMTGGTWDTHSESFQGKVA 158
Cdd:PRK09802  93 KRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEG-VELLMTGGHLRRQSQSFYGDQA 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 159 ESVLRSYDFDQLFIGADGIDLDRGTTTFNELVG-LSKVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSD 237
Cdd:PRK09802 172 EQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEArLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPA 251


                 .
gi 487833139 238 E 238
Cdd:PRK09802 252 D 252
PRK10906 PRK10906
DeoR/GlpR family transcriptional regulator;
7-250 3.26e-23

DeoR/GlpR family transcriptional regulator;


Pssm-ID: 182827 [Multi-domain]  Cd Length: 252  Bit Score: 94.54  E-value: 3.26e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   7 QLRRH-TIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAiALPKEVMHDELNEKV---SVRKISL 82
Cdd:PRK10906   3 QTQRHdAIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNDLAEQNKILRHHGGA-ALPSSSVNTPWHDRKatqTEEKERI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  83 AKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRGLVVMTNSLHVANALNELENEpTLLMTGGTWDTHSESFQGKVAESVL 162
Cdd:PRK10906  82 ARKVASQIPNGATLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMAKEDF-RIILAGGELRSRDGGIIGEATLDFI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 163 RSYDFDQLFIGADGIDLDRGTTTFN-ELVGLSKVMAEVSREVIVMIESDKVGRK-IPNLElSWDNIDVLVTDHELSDEFA 240
Cdd:PRK10906 161 SQFRLDFGILGISGIDSDGSLLEFDyHEVRTKRAIIENSRHVMLVVDHSKFGRNaMVNMG-SISMVDAVYTDQLPPASVM 239

                        250
                 ....*....|
gi 487833139 241 KQIESHQVRV 250
Cdd:PRK10906 240 QVIEDHHVQL 249
PRK13509 PRK13509
HTH-type transcriptional regulator UlaR;
5-253 7.52e-20

HTH-type transcriptional regulator UlaR;


Pssm-ID: 184100 [Multi-domain]  Cd Length: 251  Bit Score: 85.44  E-value: 7.52e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   5 NTQLRRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEVMH----DELNEKVSVRKI 80
Cdd:PRK13509   2 TEAQRHQILLELLAQLGFVTVEKVIERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRwtpmNIHQAQNHDEKV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  81 SLAKAAAKLIRDHNRIVIDSGSTTAALIQQLNDkRGLVVMTNSLHVANALNELENEPTLLMtGGTWDtHSESFQGKVAES 160
Cdd:PRK13509  82 RIAKAASQLCNPGESVVINCGSTAFLLGRELCG-KPVQIITNYLPLANYLIDQEHDSVIIM-GGQYN-KSQSITLSPQGS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 161 VLRSYDFDQLFIGADGIDLDrGTTTFNELVGLS-KVMAEVSREVIVMIESDKVGRKIPNLELSWDNIDVLVTDHELSDEF 239
Cdd:PRK13509 159 ENSLYAGHWMFTSGKGLTAD-GLYKTDMLTAMAeQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNADPEV 237

                        250
                 ....*....|....
gi 487833139 240 AKQIESHQVRVIRA 253
Cdd:PRK13509 238 LQQLEAQGVSILLV 251
PRK10681 PRK10681
DNA-binding transcriptional repressor DeoR; Provisional
 35-251 3.42e-14

DNA-binding transcriptional repressor DeoR; Provisional


Pssm-ID: 182644 [Multi-domain]  Cd Length: 252  Bit Score: 70.11  E-value: 3.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  35 SEVTIRKDLASLEKNGQLLrryGGAIAL-PKEVMH----DELNEKVsVRKISLAKAAAKLIRDHNRIVIDSGSTTAALIQ 109
Cdd:PRK10681  34 SEMTIRRDLNAHSAPVVLL---GGYIVLePRSASHyllsDQKSRLV-EEKRRAAQLAATLVEPNQTLFFDCGTTTPWIIE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139 110 QLNDKRGLVVMTNSLHVANALNELENEPTLLmTGGTWDTHSESFQGKVAESVLRSYDFDQLFIGADGIDLDRGTTTFN-- 187
Cdd:PRK10681 110 AIDNELPFTAVCYSLNTFLALQEKPHCRAIL-CGGEFHASNAIFKPLDFQQTLDNICPDIAFYSAAGVHVSKGATCFNle 188

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 487833139 188 ELVGLSKVMAEVSREVIVmIESDKVGRKIPNLELSWDNIDVLVTDHELSDEFAKQIESHQVRVI 251
Cdd:PRK10681 189 ELPVKHWAMAMAQKHVLV-VDHSKFGKVRPARMGDLTRFDTVVSDRCPDDEFVKYAQAQRIKLM 251
PRK10411 PRK10411
L-fucose operon activator;
9-178 4.96e-13

L-fucose operon activator;


Pssm-ID: 236684 [Multi-domain]  Cd Length: 240  Bit Score: 66.75  E-value: 4.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139   9 RRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIALPKEV------MHDELNEKVSvRKISL 82
Cdd:PRK10411   5 RQQAIVDLLLNHTSLTTEALAEQLNVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNqdsgdpFHIRLKSHYA-HKADI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487833139  83 AKAAAKLIRDHNRIVIDSGSTTAALIQQLNDKRgLVVMTNSLHVANALNELEnEPTLLMTGGTWDTHSESFQGKVAESVL 162
Cdd:PRK10411  84 AREALAWIEEGMVIALDASSTCWYLARQLPDIN-IQVFTNSHPICQELGKRE-RIQLISSGGTLERKYGCYVNPSLISQL 161

                        170
                 ....*....|....*.
gi 487833139 163 RSYDFDQLFIGADGID 178
Cdd:PRK10411 162 KSLEIDLFIFSCEGID 177
HTH_DEOR smart00420
helix_turn_helix, Deoxyribose operon repressor;
9-60 4.61e-11

helix_turn_helix, Deoxyribose operon repressor;


Pssm-ID: 197714 [Multi-domain]  Cd Length: 53  Bit Score: 56.85  E-value: 4.61e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 487833139     9 RRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAI 60
Cdd:smart00420   1 RQQQILELLAQQGKVSVEELAELLGVSEMTIRRDLNKLEEQGLLTRVHGGAV 52
HTH_DeoR pfam08220
DeoR-like helix-turn-helix domain;
9-62 4.95e-10

DeoR-like helix-turn-helix domain;


Pssm-ID: 285436 [Multi-domain]  Cd Length: 57  Bit Score: 53.80  E-value: 4.95e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 487833139    9 RRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRYGGAIAL 62
Cdd:pfam08220   1 RIQQILELLKQQGTLSVEELAELLGVSEMTIRRDLNELEEQGLLTRTHGGAVSN 54
HTH_11 pfam08279
HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.
 16-50 3.13e-03

HTH domain; This family includes helix-turn-helix domains in a wide variety of proteins.


Pssm-ID: 429896 [Multi-domain]  Cd Length: 52  Bit Score: 34.72  E-value: 3.13e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 487833139   16 LVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNG 50
Cdd:pfam08279   7 LLEARGPISGQELAEKLGVSRRTIRRDIKILEELG 41
COG2345 COG2345
Predicted transcriptional regulator, ArsR family [Transcription];
9-56 3.43e-03

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441914 [Multi-domain]  Cd Length: 217  Bit Score: 37.60  E-value: 3.43e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 487833139   9 RRHTIVKLVNEQGEVSVEALSSQFETSEVTIRKDLASLEKNGQLLRRY 56
Cdd:COG2345   14 TRRRILELLKRAGPVTAAELAEALGLTPNAVRRHLDALEEEGLVERET 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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