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Conserved domains on  [gi|487907693|ref|WP_001981159|]
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DnaA N-terminal domain-containing protein [Bacillus tropicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06672 super family cl32159
hypothetical protein; Validated
 1-345 0e+00

hypothetical protein; Validated


The actual alignment was detected with superfamily member PRK06672:

Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 524.33  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693   1 MKINWAEVKGKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIQFNLSNDE 80
Cdd:PRK06672   1 MKINWTEVKEKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIQFDLCNGE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693  81 PSNLKDVQKERLSSWDEIKKALRPKLAEKTFLTWIRNTNATIEDNKLIIFCEDAFHRDLLEGEYKNIISSTVQKLSNEEY 160
Cdd:PRK06672  81 PSNLKDVQKEKLSSWDEVKKALRPKIAEKTFMTWIRNTNATIKDNKVIIFCEDAFHRDLLEGEYKNIISSTVQKITDEEY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693 161 QIWFEIKSNATSIAQIHHVQKNQLTSEQEESSTIWNKIKEKMQLTISRPSYETWVKETTASIKENSLTIYFENEFQQEWV 240
Cdd:PRK06672 161 QIWFEIGSSATSKAQVHHVKNNQRTSGQEESKTIWNKIKDKMQLKISRPSYETWVKETTARINEDSLIIYFENEFQQEWV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693 241 KKSYKDLISQIAKELTGNTYEIQFELKSNTNTTdngeKSKSTIEDITSELGEQFKVSNNSLKYNDVDESNKRIRALEEKI 320
Cdd:PRK06672 241 KKSYKDLISQIAKELTGNTYEIQFELKSNTTSN----NEKSTIKDITSELGEQFKVSNNSLKYNDVDESNKRIRALEEKI 316

                        330       340
                 ....*....|....*....|....*
gi 487907693 321 MKLERTIGTLVGKLDAVELKTQLEK 345
Cdd:PRK06672 317 MNLEKVIGTLVEKLDAVELKTQLEK 341
 
Name Accession Description Interval E-value
PRK06672 PRK06672
hypothetical protein; Validated
 1-345 0e+00

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 524.33  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693   1 MKINWAEVKGKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIQFNLSNDE 80
Cdd:PRK06672   1 MKINWTEVKEKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIQFDLCNGE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693  81 PSNLKDVQKERLSSWDEIKKALRPKLAEKTFLTWIRNTNATIEDNKLIIFCEDAFHRDLLEGEYKNIISSTVQKLSNEEY 160
Cdd:PRK06672  81 PSNLKDVQKEKLSSWDEVKKALRPKIAEKTFMTWIRNTNATIKDNKVIIFCEDAFHRDLLEGEYKNIISSTVQKITDEEY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693 161 QIWFEIKSNATSIAQIHHVQKNQLTSEQEESSTIWNKIKEKMQLTISRPSYETWVKETTASIKENSLTIYFENEFQQEWV 240
Cdd:PRK06672 161 QIWFEIGSSATSKAQVHHVKNNQRTSGQEESKTIWNKIKDKMQLKISRPSYETWVKETTARINEDSLIIYFENEFQQEWV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693 241 KKSYKDLISQIAKELTGNTYEIQFELKSNTNTTdngeKSKSTIEDITSELGEQFKVSNNSLKYNDVDESNKRIRALEEKI 320
Cdd:PRK06672 241 KKSYKDLISQIAKELTGNTYEIQFELKSNTTSN----NEKSTIKDITSELGEQFKVSNNSLKYNDVDESNKRIRALEEKI 316

                        330       340
                 ....*....|....*....|....*
gi 487907693 321 MKLERTIGTLVGKLDAVELKTQLEK 345
Cdd:PRK06672 317 MNLEKVIGTLVEKLDAVELKTQLEK 341
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 195-315 3.00e-13

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 70.25  E-value: 3.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693  195 WNKIKEKMQLTISRPSYETWVKETTA-SIKENSLTIYFENEFQQEWVKKSYKDLISQIAKELTGNTYEIQFELKSntNTT 273
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGE--DEE 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 487907693  274 DNGEKSKSTIEDITSELGEQFKVSNNSLKYN-D---VDESNKRIRA 315
Cdd:TIGR00362  79 ELEPNSKKPEPAPPEAPAPPSSASGLNPKYTfDnfvVGKSNRLAHA 124
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
 192-254 4.07e-12

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 60.76  E-value: 4.07e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 487907693  192 STIWNKIKEKMQLTISRPSYETWVKETTASIKEN--SLTIYFENEFQQEWVKKSYKDLISQIAKE 254
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVDLDDggSLTLSVPNRFVRDWVEEHYLDRILELWQE 65
 
Name Accession Description Interval E-value
PRK06672 PRK06672
hypothetical protein; Validated
 1-345 0e+00

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 524.33  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693   1 MKINWAEVKGKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIQFNLSNDE 80
Cdd:PRK06672   1 MKINWTEVKEKIRPQISKPSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIQFDLCNGE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693  81 PSNLKDVQKERLSSWDEIKKALRPKLAEKTFLTWIRNTNATIEDNKLIIFCEDAFHRDLLEGEYKNIISSTVQKLSNEEY 160
Cdd:PRK06672  81 PSNLKDVQKEKLSSWDEVKKALRPKIAEKTFMTWIRNTNATIKDNKVIIFCEDAFHRDLLEGEYKNIISSTVQKITDEEY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693 161 QIWFEIKSNATSIAQIHHVQKNQLTSEQEESSTIWNKIKEKMQLTISRPSYETWVKETTASIKENSLTIYFENEFQQEWV 240
Cdd:PRK06672 161 QIWFEIGSSATSKAQVHHVKNNQRTSGQEESKTIWNKIKDKMQLKISRPSYETWVKETTARINEDSLIIYFENEFQQEWV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693 241 KKSYKDLISQIAKELTGNTYEIQFELKSNTNTTdngeKSKSTIEDITSELGEQFKVSNNSLKYNDVDESNKRIRALEEKI 320
Cdd:PRK06672 241 KKSYKDLISQIAKELTGNTYEIQFELKSNTTSN----NEKSTIKDITSELGEQFKVSNNSLKYNDVDESNKRIRALEEKI 316

                        330       340
                 ....*....|....*....|....*
gi 487907693 321 MKLERTIGTLVGKLDAVELKTQLEK 345
Cdd:PRK06672 317 MNLEKVIGTLVEKLDAVELKTQLEK 341
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 195-315 3.00e-13

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 70.25  E-value: 3.00e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693  195 WNKIKEKMQLTISRPSYETWVKETTA-SIKENSLTIYFENEFQQEWVKKSYKDLISQIAKELTGNTYEIQFELKSntNTT 273
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGE--DEE 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 487907693  274 DNGEKSKSTIEDITSELGEQFKVSNNSLKYN-D---VDESNKRIRA 315
Cdd:TIGR00362  79 ELEPNSKKPEPAPPEAPAPPSSASGLNPKYTfDnfvVGKSNRLAHA 124
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 5-90 3.73e-13

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 69.87  E-value: 3.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693    5 WAEVKGKIRPQISKPSYETWFTNTTVY-LEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIQFNLSNDEPSN 83
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLLsIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEEL 80


                  ....*..
gi 487907693   84 LKDVQKE 90
Cdd:TIGR00362  81 EPNSKKP 87
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
 192-254 4.07e-12

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 60.76  E-value: 4.07e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 487907693  192 STIWNKIKEKMQLTISRPSYETWVKETTASIKEN--SLTIYFENEFQQEWVKKSYKDLISQIAKE 254
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVDLDDggSLTLSVPNRFVRDWVEEHYLDRILELWQE 65
dnaA PRK00149
chromosomal replication initiator protein DnaA;
1-71 4.08e-12

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 66.70  E-value: 4.08e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 487907693   1 MKINWAEVKGKIRPQISKPSYETWFTNTTVY-LEDDILTIYCPNEFARDWLESHYKELVFNTLRemFNT--TFE 71
Cdd:PRK00149   2 LQSLWEKVLERLKDELSEQEYETWIKPLKALsLEDNTLTLYVPNRFVKDWIEKNYLDLIEEALQ--LNPkyTFD 73
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
 5-64 7.30e-12

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 59.99  E-value: 7.30e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487907693    5 WAEVKGKIRPQISKPSYETWFTNTTV--YLEDDILTIYCPNEFARDWLESHYKELVFNTLRE 64
Cdd:pfam11638   4 WERVLERLRKEVGEQTFNTWIKPLTLvdLDDGGSLTLSVPNRFVRDWVEEHYLDRILELWQE 65
dnaA PRK00149
chromosomal replication initiator protein DnaA;
192-253 6.95e-10

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 59.76  E-value: 6.95e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 487907693 192 STIWNKIKEKMQLTISRPSYETWVKETT-ASIKENSLTIYFENEFQQEWVKKSYKDLISQIAK 253
Cdd:PRK00149   3 QSLWEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEALQ 65
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 95-193 1.25e-09

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 59.08  E-value: 1.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693   95 WDEIKKALRPKLAEKTFLTWIRNTNA-TIEDNKLIIFCEDAFHRDLLEGEYKNIISSTVQKLSNEEYQIWFEIKSNATSI 173
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEEL 80

                          90       100
                  ....*....|....*....|
gi 487907693  174 AQIHHVQKNQLTSEQEESST 193
Cdd:TIGR00362  81 EPNSKKPEPAPPEAPAPPSS 100
dnaA PRK00149
chromosomal replication initiator protein DnaA;
95-153 8.03e-06

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 47.05  E-value: 8.03e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693  95 WDEIKKALRPKLAEKTFLTWIRNTN-ATIEDNKLIIFCEDAFHRDLLEGEYKNIISSTVQ 153
Cdd:PRK00149   6 WEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEALQ 65
polC PRK00448
DNA polymerase III PolC; Validated
 19-165 2.11e-04

DNA polymerase III PolC; Validated


Pssm-ID: 234767 [Multi-domain]  Cd Length: 1437  Bit Score: 43.29  E-value: 2.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693   19 PSYETWFTNTTVYLEDDILTIYCPNEFARDWLESHYKELVFNTLREMFNTTFEIQFnLSNDEPSNLKDVQKERLSSWDEI 98
Cdd:PRK00448  108 PLFKSLLKKQKVEVEGNKLIIKVNNEIERDHLKKKHLPKLIKQYEKFGFGILKIDF-EIDDSKEELEKFEAQKEEEDEKL 186

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 487907693   99 KKALRPKLAEKTFLTWIRNTNATIEDNKLIIfcedafHRDLLEGEYKNIISstvqkLSNEEYQIWFE 165
Cdd:PRK00448  187 AKEALEAMKKLEAEKKKQSKNFDPKEGPVQI------GKKIDKEEITPMKE-----INEEERRVVVE 242
polC PRK00448
DNA polymerase III PolC; Validated
 58-212 6.32e-03

DNA polymerase III PolC; Validated


Pssm-ID: 234767 [Multi-domain]  Cd Length: 1437  Bit Score: 38.67  E-value: 6.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693   58 VFNTLREMFNTTF------EIQFNLSNDEPSNLKDVQKERLSSWDEIKKALRPKLaeKTFLTwirNTNATIEDNKLIIFC 131
Cdd:PRK00448   56 DFKLFKEKLKQSFshiadiKVTFSIEVENITFTEELLLDYWNEIIEKAKKNSPLF--KSLLK---KQKVEVEGNKLIIKV 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487907693  132 EDAFHRDLLEGEYKNIISSTVQKLSNEEYQIWFEIKSNATSIAQIHHVQknqltsEQEESSTIWNKIKEKMQLTISRPSY 211
Cdd:PRK00448  131 NNEIERDHLKKKHLPKLIKQYEKFGFGILKIDFEIDDSKEELEKFEAQK------EEEDEKLAKEALEAMKKLEAEKKKQ 204


                  .
gi 487907693  212 E 212
Cdd:PRK00448  205 S 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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