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Conserved domains on  [gi|487910442|ref|WP_001983908|]
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MULTISPECIES: enoyl-CoA hydratase/isomerase family protein [Acinetobacter]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
24-340 5.94e-109

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 322.11  E-value: 5.94e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   24 RIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALD 103
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  104 LLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGLFTGLTGSIMTA 181
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLS-RlpGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  182 AGAYSIGWATHICE-AQRDNVLQKVLNINWahypaGDFRAIDDTLNSLHR--PVAAGPLQNSLDVIHSVCRGSSFEQDYQ 258
Cdd:pfam16113 161 ADALAAGLATHYVPsARLPALEEALAALDW-----SDPADVDAVLAEFAEesDPPPSPLAAHREAIDRCFSADTVEEIIA 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  259 AIVSLRDAsSDWLRQASENLQKGSPSTAAITWLLWQWGKQVhSWDEVFDLEAQISEWKIRHPDFVEGVRARLVDKDLSPE 338
Cdd:pfam16113 236 ALEAEADG-DEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL-SLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPK 313

                  ..
gi 487910442  339 WK 340
Cdd:pfam16113 314 WS 315
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
24-340 5.94e-109

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 322.11  E-value: 5.94e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   24 RIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALD 103
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  104 LLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGLFTGLTGSIMTA 181
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLS-RlpGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  182 AGAYSIGWATHICE-AQRDNVLQKVLNINWahypaGDFRAIDDTLNSLHR--PVAAGPLQNSLDVIHSVCRGSSFEQDYQ 258
Cdd:pfam16113 161 ADALAAGLATHYVPsARLPALEEALAALDW-----SDPADVDAVLAEFAEesDPPPSPLAAHREAIDRCFSADTVEEIIA 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  259 AIVSLRDAsSDWLRQASENLQKGSPSTAAITWLLWQWGKQVhSWDEVFDLEAQISEWKIRHPDFVEGVRARLVDKDLSPE 338
Cdd:pfam16113 236 ALEAEADG-DEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL-SLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPK 313

                  ..
gi 487910442  339 WK 340
Cdd:pfam16113 314 WS 315
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
13-340 8.30e-79

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 245.50  E-value: 8.30e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  13 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETA 92
Cdd:PRK05617   3 DEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPLAA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  93 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGL 170
Cdd:PRK05617  83 DRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLS-RapGALGT 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 171 FTGLTGSIMTAAGAYSIGWATH-ICEAQRDNVLQKVLNINWAHYPAGdfraIDDTLNSLHRPVAAGPLQNSLDVIHSVCR 249
Cdd:PRK05617 162 YLALTGARISAADALYAGLADHfVPSADLPALLDALISLRWDSGADV----VDAALAAFATPAPASELAAQRAWIDECFA 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 250 GSSFEqdyqAIV-SLRDASSDWLRQASENLQKGSPSTAAITWllwqwgKQVH-----SWDEVFDLEAQISEWKIRHPDFV 323
Cdd:PRK05617 238 GDTVE----DIIaALEADGGEFAAKTADTLRSRSPTSLKVTL------EQLRrarglTLEECLRRELRLALAMLRSPDFV 307
                        330
                 ....*....|....*..
gi 487910442 324 EGVRARLVDKDLSPEWK 340
Cdd:PRK05617 308 EGVRAVLIDKDRNPKWS 324
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
15-208 3.69e-45

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 153.87  E-value: 3.69e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  15 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDVRKLRQLviNQEVETANK 94
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAAL--SDAGEEARA 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  95 FFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR--GQIGLFT 172
Cdd:cd06558   78 FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLvgPARAREL 157
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 487910442 173 GLTGSIMTAAGAYSIGWATHICEAqrDNVLQKVLNI 208
Cdd:cd06558  158 LLTGRRISAEEALELGLVDEVVPD--EELLAAALEL 191
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
18-196 8.92e-35

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 128.36  E-value: 8.92e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  18 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDvrkLRQLVINQEVETANKFFQ 97
Cdd:COG1024    4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGAD---LKELAAAADPEEARAFAR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  98 QEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIG------LF 171
Cdd:COG1024   80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRL--VGlarakeLL 157
                        170       180
                 ....*....|....*....|....*
gi 487910442 172 tgLTGSIMTAAGAYSIGWATHICEA 196
Cdd:COG1024  158 --LTGRRIDAEEALELGLVNRVVPD 180
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
18-162 2.88e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 67.94  E-value: 2.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   18 EAKNGWRIVRLNRPKS-LHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFF 96
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEG 97
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 487910442   97 QQEYAldlLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSR--LAMPEINIGLYPDVGASRFL 162
Cdd:TIGR02441  98 QEMFE---RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRL 162
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
24-340 5.94e-109

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 322.11  E-value: 5.94e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   24 RIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALD 103
Cdd:pfam16113   2 GVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGGGEAGRDFFREEYRLN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  104 LLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGLFTGLTGSIMTA 181
Cdd:pfam16113  82 YLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLS-RlpGELGLYLALTGARLNG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  182 AGAYSIGWATHICE-AQRDNVLQKVLNINWahypaGDFRAIDDTLNSLHR--PVAAGPLQNSLDVIHSVCRGSSFEQDYQ 258
Cdd:pfam16113 161 ADALAAGLATHYVPsARLPALEEALAALDW-----SDPADVDAVLAEFAEesDPPPSPLAAHREAIDRCFSADTVEEIIA 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  259 AIVSLRDAsSDWLRQASENLQKGSPSTAAITWLLWQWGKQVhSWDEVFDLEAQISEWKIRHPDFVEGVRARLVDKDLSPE 338
Cdd:pfam16113 236 ALEAEADG-DEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL-SLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPK 313

                  ..
gi 487910442  339 WK 340
Cdd:pfam16113 314 WS 315
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
13-340 8.30e-79

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 245.50  E-value: 8.30e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  13 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETA 92
Cdd:PRK05617   3 DEVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRALYEAARAGDPLAA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  93 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdR--GQIGL 170
Cdd:PRK05617  83 DRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLS-RapGALGT 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 171 FTGLTGSIMTAAGAYSIGWATH-ICEAQRDNVLQKVLNINWAHYPAGdfraIDDTLNSLHRPVAAGPLQNSLDVIHSVCR 249
Cdd:PRK05617 162 YLALTGARISAADALYAGLADHfVPSADLPALLDALISLRWDSGADV----VDAALAAFATPAPASELAAQRAWIDECFA 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 250 GSSFEqdyqAIV-SLRDASSDWLRQASENLQKGSPSTAAITWllwqwgKQVH-----SWDEVFDLEAQISEWKIRHPDFV 323
Cdd:PRK05617 238 GDTVE----DIIaALEADGGEFAAKTADTLRSRSPTSLKVTL------EQLRrarglTLEECLRRELRLALAMLRSPDFV 307
                        330
                 ....*....|....*..
gi 487910442 324 EGVRARLVDKDLSPEWK 340
Cdd:PRK05617 308 EGVRAVLIDKDRNPKWS 324
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
15-208 3.69e-45

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 153.87  E-value: 3.69e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  15 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDVRKLRQLviNQEVETANK 94
Cdd:cd06558    1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAAL--SDAGEEARA 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  95 FFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR--GQIGLFT 172
Cdd:cd06558   78 FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLvgPARAREL 157
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 487910442 173 GLTGSIMTAAGAYSIGWATHICEAqrDNVLQKVLNI 208
Cdd:cd06558  158 LLTGRRISAEEALELGLVDEVVPD--EELLAAALEL 191
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
13-339 1.51e-42

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 153.21  E-value: 1.51e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  13 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETA 92
Cdd:PLN02851  42 DQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSGADVVSLYHLINEGNVEEC 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  93 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD-RGQIGLF 171
Cdd:PLN02851 121 KLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRlPGYLGEY 200
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 172 TGLTGSIMTAAGAYSIGWATHICEAQRDNVLQK-----------VLNINWAHYpaGDFRAIDDTlNSLHRpvaagplqns 240
Cdd:PLN02851 201 LALTGQKLNGVEMIACGLATHYCLNARLPLIEErlgklltddpaVIEDSLAQY--GDLVYPDKS-SVLHK---------- 267
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 241 LDVIHSVCRGSSFEQDYQAIVSLRDASSD-WLRQASENLQKGSPSTAAITWLLWQWGKqVHSWDEVFDLEAQIS---EWK 316
Cdd:PLN02851 268 IETIDKCFGHDTVEEIIEALENEAASSYDeWCKKALKKIKEASPLSLKVTLQSIREGR-FQTLDQCLAREYRISlcgVSK 346
                        330       340
                 ....*....|....*....|...
gi 487910442 317 IRHPDFVEGVRARLVDKDLSPEW 339
Cdd:PLN02851 347 WVSGDFCEGVRARLVDKDFAPKW 369
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
15-340 3.18e-41

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 149.10  E-value: 3.18e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  15 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANK 94
Cdd:PLN02988  11 VLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRDIEQGNWRLGAN 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  95 FFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD-RGQIGLFTG 173
Cdd:PLN02988  90 FFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRlPGFFGEYVG 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 174 LTGSIMTAAGAYSIGWATHICEAQRDNVLQKVLNINWAHYPAgdFRAIDDTLNSLHRPVAAGPLQNSLDVIHSVCRGSSF 253
Cdd:PLN02988 170 LTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPT--FASTILDAYTQHPRLKPQSAYHRLDVIDRCFSRRTV 247
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 254 EQDYQAIVslRDASSD---WLRQASENLQKGSPSTAAITWLLWQWGK-------QVHSWDEVFD-LEAQISEwkirhpDF 322
Cdd:PLN02988 248 EEIISALE--REATQEadgWISATIQALKKASPASLKISLRSIREGRlqgvgqcLIREYRMVCHvMKGEISK------DF 319
                        330
                 ....*....|....*...
gi 487910442 323 VEGVRARLVDKDLSPEWK 340
Cdd:PLN02988 320 VEGCRAILVDKDKNPKWE 337
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
15-346 8.47e-41

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 147.64  E-value: 8.47e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  15 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANK 94
Cdd:PLN02874  13 VLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMFYDGRESDDSCLEVV 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  95 FfqQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD-RGQIGLFTG 173
Cdd:PLN02874  92 Y--RMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRlPGHLGEYLA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 174 LTGSIMTAAGAYSIGWATHICEAQRDNVLQK-VLNINwahypAGDFRAIDDTLNSLHRPVAAGP--LQNSLDVIHSVCRG 250
Cdd:PLN02874 170 LTGARLNGKEMVACGLATHFVPSEKLPELEKrLLNLN-----SGDESAVQEAIEEFSKDVQADEdsILNKQSWINECFSK 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 251 SSFEQDYQAIVS-LRDASSDWLRQASENLQKGSPSTAAITWLLWQWGKQvHSWDEVFDLEAQISEWKIR---HPDFVEGV 326
Cdd:PLN02874 245 DTVEEIIKAFESeASKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRK-QSLAECLKKEFRLTMNILRstvSDDVYEGI 323
                        330       340
                 ....*....|....*....|..
gi 487910442 327 RARLVDKDLSPEW--KACEDLT 346
Cdd:PLN02874 324 RALVIDKDNAPKWnpSTLDEVT 345
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
18-196 8.92e-35

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 128.36  E-value: 8.92e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  18 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDvrkLRQLVINQEVETANKFFQ 97
Cdd:COG1024    4 EREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGAD---LKELAAAADPEEARAFAR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  98 QEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIG------LF 171
Cdd:COG1024   80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRL--VGlarakeLL 157
                        170       180
                 ....*....|....*....|....*
gi 487910442 172 tgLTGSIMTAAGAYSIGWATHICEA 196
Cdd:COG1024  158 --LTGRRIDAEEALELGLVNRVVPD 180
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
15-345 7.21e-32

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 124.03  E-value: 7.21e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  15 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANK 94
Cdd:PLN02157  39 VLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSLYHLRKRGSPDAIRE 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  95 FFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD-RGQIGLFTG 173
Cdd:PLN02157 118 FFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHlPGRLGEYLG 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 174 LTGSIMTAAGAYSIGWATHICEAQRDNVLQKVLNINWAHYPAGDFRAIDDTLNSLHrPVAAGPLQNsLDVIHSVCRGSSF 253
Cdd:PLN02157 198 LTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLLTDDPSVVESCLEKCAEVAH-PEKTGVIRR-IDLLEKCFSHDTV 275
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 254 EQ--DYQAIVSLRDASSdWLRQASENLQKGSPSTAAITWLLWQWGKqVHSWDEVFDLEAQISEWKIRHP---DFVEGVRA 328
Cdd:PLN02157 276 EEiiDSLEIEAGRRKDT-WCITTLRRLKESSPLSLKVALRSIREGR-LQTLDQCLIREYRMSLQGLIGPmsgNFCEGVRA 353
                        330       340
                 ....*....|....*....|...
gi 487910442 329 RLVDKDLSPEW------KACEDL 345
Cdd:PLN02157 354 RLIDKDEAPKWdppsleKVSEDM 376
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
18-165 3.76e-23

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 97.05  E-value: 3.76e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   18 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTtPKAFCAGGDVRKLRQLVINQEVETANKFfq 97
Cdd:pfam00378   1 EINAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEGPAHQALYRENV-- 77
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 487910442   98 qeYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR 165
Cdd:pfam00378  78 --LDLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRI 143
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
11-237 7.11e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 85.30  E-value: 7.11e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  11 HPDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQL--VINQE 88
Cdd:PRK06688   3 MVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVL-TGAGRAFSAGGDIKDFPKAppKPPDE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  89 VETANKFFQQeyaldllLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAdrgQI 168
Cdd:PRK06688  82 LAPVNRFLRA-------IAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLP---RL 151
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 487910442 169 glfTG--------LTGSIMTAAGAYSIGWATHIceaqrdnvlqkvlninwahYPAGDFRAIDDtlnSLHRPVAAGPL 237
Cdd:PRK06688 152 ---IGraraaemlLLGEPLSAEEALRIGLVNRV-------------------VPAAELDAEAD---AQAAKLAAGPA 203
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
13-195 5.04e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 82.62  E-value: 5.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  13 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLrqlvinqevetA 92
Cdd:PRK07509   3 DRVSVTIEDGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVIL-SGEGGAFCAGLDVKSV-----------A 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  93 NKFFQQEYALDLLLH---NYAK-----------PVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGA 158
Cdd:PRK07509  71 SSPGNAVKLLFKRLPgnaNLAQrvslgwrrlpvPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAG 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 487910442 159 SRFLadRGQIG-----LFTgLTGSIMTAAGAYSIGWATHICE 195
Cdd:PRK07509 151 TVSL--RGLVRkdvarELT-YTARVFSAEEALELGLVTHVSD 189
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
15-195 8.53e-18

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 82.10  E-value: 8.53e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  15 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETA-- 92
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGll 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  93 -NKFFQQeyaldllLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQIGLF 171
Cdd:PRK05809  86 gNKVFRK-------LENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKA 158
                        170       180
                 ....*....|....*....|....*.
gi 487910442 172 TGL--TGSIMTAAGAYSIGWATHICE 195
Cdd:PRK05809 159 KELiyTGDMINAEEALRIGLVNKVVE 184
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
13-193 1.67e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 81.34  E-value: 1.67e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  13 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETA 92
Cdd:PRK05980   3 DTVLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVAL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  93 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFL---ADRGQiG 169
Cdd:PRK05980  83 RDFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLprlAGRKR-A 161
                        170       180
                 ....*....|....*....|....
gi 487910442 170 LFTGLTGSIMTAAGAYSIGWATHI 193
Cdd:PRK05980 162 LELLLTGDAFSAERALEIGLVNAV 185
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
12-208 5.12e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 80.10  E-value: 5.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  12 PDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRklrqlvinqEVET 91
Cdd:PRK08138   7 DVVLLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVL-TGGEKVFAAGADIK---------EFAT 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  92 ANkffqqeyALDLLL---HNY-------AKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRF 161
Cdd:PRK08138  77 AG-------AIEMYLrhtERYweaiaqcPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQR 149
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 487910442 162 LAdRGqIGLFTG----LTGSIMTAAGAYSIGWATHICEaqRDNVLQKVLNI 208
Cdd:PRK08138 150 LV-RA-VGKFKAmrmaLTGCMVPAPEALAIGLVSEVVE--DEQTLPRALEL 196
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
9-196 7.02e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 79.75  E-value: 7.02e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   9 SYHPDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQE 88
Cdd:PRK06127   7 SSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAE 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  89 VETAnkFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADrgQI 168
Cdd:PRK06127  87 AVAA--YEQAVEAAQAALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVD--LV 162
                        170       180       190
                 ....*....|....*....|....*....|....
gi 487910442 169 G------LFtgLTGSIMTAAGAYSIGWATHICEA 196
Cdd:PRK06127 163 GpsaakdLF--YTARRFDAAEALRIGLVHRVTAA 194
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
14-197 6.84e-15

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 73.65  E-value: 6.84e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  14 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVInqeVETAN 93
Cdd:PRK09674   3 ELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVI-TGNARFFAAGADLNEMAEKDL---AATLN 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  94 KFFQQEYALdllLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAS-RFLADRGQ-IGLF 171
Cdd:PRK09674  79 DPRPQLWQR---LQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTqRLIRSVGKsLASQ 155
                        170       180
                 ....*....|....*....|....*.
gi 487910442 172 TGLTGSIMTAAGAYSIGWATHICEAQ 197
Cdd:PRK09674 156 MVLTGESITAQQAQQAGLVSEVFPPE 181
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
16-208 1.61e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 72.84  E-value: 1.61e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  16 VEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVR---KLRQLVINQEV--- 89
Cdd:PRK07657   7 VDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKeraGMNEEQVRHAVsli 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  90 -ETANKFFQqeyaldlllhnYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQI 168
Cdd:PRK07657  87 rTTMEMVEQ-----------LPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGV 155
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 487910442 169 GLFTGL--TGSIMTAAGAYSIGWATHICEaqRDNVLQKVLNI 208
Cdd:PRK07657 156 GRAKELiyTGRRISAQEAKEIGLVEFVVP--AHLLEEKAIEI 195
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
25-195 2.07e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 69.30  E-value: 2.07e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  25 IVRLNRPKSLHALDESIVTALLRVFEDF-RDDEQVKAIwLDSTTPKAFCAGGDvrkLRQLVINQEVETANKFF---QQEY 100
Cdd:PRK06494  16 IVTLNRPEVMNALHLDAHFELEEVFDDFaADPEQWVAI-VTGAGDKAFSAGND---LKEQAAGGKRGWPESGFgglTSRF 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 101 ALDlllhnyaKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADrgQIGLFTG----LTG 176
Cdd:PRK06494  92 DLD-------KPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPR--QIGLKRAmgmiLTG 162
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 487910442 177 SIMTAAGAYSIG-----------------WATHICE 195
Cdd:PRK06494 163 RRVTAREGLELGfvnevvpagellaaaerWADDILA 198
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
9-184 2.45e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 66.22  E-value: 2.45e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   9 SYHPDLVVEEAKNGwrIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRklrqlvinqe 88
Cdd:PRK05862   2 AYETILVETRGRVG--LITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVI-TGSEKAFAAGADIK---------- 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  89 vETANKFFQQEYALDLL-----LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAS---- 159
Cdd:PRK05862  69 -EMADLSFMDVYKGDYItnwekVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSqrlt 147
                        170       180
                 ....*....|....*....|....*
gi 487910442 160 RFLADRGQIGLFtgLTGSIMTAAGA 184
Cdd:PRK05862 148 RAVGKAKAMDLC--LTGRMMDAAEA 170
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
18-162 2.88e-12

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 67.94  E-value: 2.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   18 EAKNGWRIVRLNRPKS-LHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFF 96
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEG 97
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 487910442   97 QQEYAldlLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSR--LAMPEINIGLYPDVGASRFL 162
Cdd:TIGR02441  98 QEMFE---RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRL 162
PLN02600 PLN02600
enoyl-CoA hydratase
26-173 7.64e-12

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 64.83  E-value: 7.64e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  26 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVrKLRQLVINQEVEtanKFFQQEYALDLL 105
Cdd:PLN02600   8 LRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADL-KERRKMSPSEVQ---KFVNSLRSTFSS 83
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 487910442 106 LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLA-----DRGQIGLFTG 173
Cdd:PLN02600  84 LEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPrlvgrSRAKELIFTG 156
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
26-198 2.61e-11

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 63.17  E-value: 2.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  26 VRLNRPKSlHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDvrkLRQLVINQEVETANKF-----FQQEY 100
Cdd:PRK03580  16 ITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWD---LKAAAEGEAPDADFGPggfagLTEIF 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 101 ALDlllhnyaKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR--GQIGLFTGLTGSI 178
Cdd:PRK03580  92 DLD-------KPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRlpPAIANEMVMTGRR 164
                        170       180
                 ....*....|....*....|
gi 487910442 179 MTAAGAYSIGWATHICEAQR 198
Cdd:PRK03580 165 MDAEEALRWGIVNRVVPQAE 184
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
26-197 2.89e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 63.02  E-value: 2.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  26 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVEtaNKFFQQEYAlDLL 105
Cdd:PRK05995  17 VTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVL-AGAGKAFCAGADLNWMKKMAGYSDDE--NRADARRLA-DML 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 106 --LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAS---RFLADRGQIGLFtgLTGSIMT 180
Cdd:PRK05995  93 raIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPyviRAMGERAARRYF--LTAERFD 170
                        170
                 ....*....|....*..
gi 487910442 181 AAGAYSIGWATHICEAQ 197
Cdd:PRK05995 171 AAEALRLGLVHEVVPAE 187
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
24-163 3.80e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 62.71  E-value: 3.80e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  24 RIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDvrkLRQLVINQEVETAnkffQQEYALD 103
Cdd:PRK07511  14 LVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVL-TGAGGFFCAGGN---LNRLLENRAKPPS----VQAASID 85
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487910442 104 LL------LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLA 163
Cdd:PRK07511  86 GLhdwiraIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLA 151
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
12-196 3.86e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 62.70  E-value: 3.86e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  12 PDLVVEEAKNGWRIVrLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLvinqevET 91
Cdd:PRK06144   8 DELLLEVRGGIARIT-FNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAF------ST 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  92 ANKFFQQEYALDLLLH---NYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPeI-----------NIG-LYPDV 156
Cdd:PRK06144  81 AEDAVAYERRIDRVLGaleQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP-IartlgnclsmsNLArLVALL 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 487910442 157 GASRFladRGQIglftgLTGSIMTAAGAYSIGWATHICEA 196
Cdd:PRK06144 160 GAARV---KDML-----FTARLLEAEEALAAGLVNEVVED 191
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
13-195 5.02e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 62.44  E-value: 5.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  13 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQlvinQEVETA 92
Cdd:PRK05870   3 DPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVV-TGAGKAFCAGADLTALGA----APGRPA 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  93 NKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADR--GQIGL 170
Cdd:PRK05870  78 EDGLRRIYDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAvgPQVAR 157
                        170       180
                 ....*....|....*....|....*
gi 487910442 171 FTGLTGSIMTAAGAYSIGWATHICE 195
Cdd:PRK05870 158 AALLFGMRFDAEAAVRHGLALMVAD 182
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
25-208 1.18e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 61.19  E-value: 1.18e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  25 IVRLNRPKSlHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLvinQEVETANKFFQQEYALDL 104
Cdd:PRK07658  14 VITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVI-HGEGRFFSAGADIKEFTSV---TEAEQATELAQLGQVTFE 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 105 LLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFL---ADRGQiGLFTGLTGSIMTA 181
Cdd:PRK07658  89 RVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLpryVGKAK-ALEMMLTSEPITG 167
                        170       180
                 ....*....|....*....|....*..
gi 487910442 182 AGAYSIGWATHICEAQRdnVLQKVLNI 208
Cdd:PRK07658 168 AEALKWGLVNGVFPEET--LLDDAKKL 192
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
15-188 1.18e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 61.20  E-value: 1.18e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  15 VVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEqvKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANK 94
Cdd:PRK07659   8 VVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESS--AHIVVLRGNGRGFSAGGDIKMMLSSNDESKFDGVMN 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  95 FFQQeyaLDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIGLFTG- 173
Cdd:PRK07659  86 TISE---IVVTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKR--VGENKAk 160
                        170
                 ....*....|....*...
gi 487910442 174 ---LTGSIMTAAGAYSIG 188
Cdd:PRK07659 161 qiiWEGKKLSATEALDLG 178
PLN02921 PLN02921
naphthoate synthase
26-132 1.32e-10

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 61.73  E-value: 1.32e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  26 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDvrklrqlvinQEVETANKFFQQEYA---- 101
Cdd:PLN02921  80 ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGD----------QAVRGKDGYVGPDDAgrln 149
                         90       100       110
                 ....*....|....*....|....*....|....
gi 487910442 102 -LDLLLH--NYAKPVVVWGEGYVMGGGLGLFMAA 132
Cdd:PLN02921 150 vLDLQIQirRLPKPVIAMVAGYAVGGGHILHMVC 183
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
13-198 2.13e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 60.37  E-value: 2.13e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  13 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPkAFCAGGDVRKLRQLVINQEVETA 92
Cdd:PRK06190   4 PILLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADP-AFCAGLDLKELGGDGSAYGAQDA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  93 NKffqqeyALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQIGLF- 171
Cdd:PRK06190  83 LP------NPSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRAr 156
                        170       180
                 ....*....|....*....|....*...
gi 487910442 172 -TGLTGSIMTAAGAYSIGWATHICEAQR 198
Cdd:PRK06190 157 rMSLTGDFLDAADALRAGLVTEVVPHDE 184
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
45-188 5.62e-10

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 61.07  E-value: 5.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  45 LLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALdllLHNYAKPVVVWGEGYVMGG 124
Cdd:PRK11154  39 VRAILKQLREDKELKGVVFISGKPDNFIAGADINMLAACKTAQEAEALARQGQQLFAE---IEALPIPVVAAIHGACLGG 115
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 125 GLGLFMAAPFRLVT--PYSRLAMPEINIGLYPDVGASRFLADRgqIGLFTG----LTGSIMTAAGAYSIG 188
Cdd:PRK11154 116 GLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRL--IGVSTAldmiLTGKQLRAKQALKLG 183
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
14-163 9.35e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 58.64  E-value: 9.35e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  14 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLV--------- 84
Cdd:PRK06072   1 MIKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIV-TGEGRAFCVGADLSEFAPDFaidlretfy 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  85 -INQEVETANKFFQQeyALDlllhnyakpvvvwgeGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLA 163
Cdd:PRK06072  80 pIIREIRFSDKIYIS--AIN---------------GVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLL 142
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
18-328 1.82e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 57.83  E-value: 1.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  18 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANKFFQ 97
Cdd:PRK07260   7 EVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANG-KVFSVGGDLVEMKRAVDEDDVQSLVKIAE 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  98 QEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAsRFLADRGqIGLFTG---- 173
Cdd:PRK07260  86 LVNEISFAIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGG-LFLLTRA-IGLNRAthla 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 174 LTGSIMTAAGAYSIGWATHICEAQRdnvLQKVLNinwahypagdfraiddtlnslhrpvaagplqnsldvihsvcrgssf 253
Cdd:PRK07260 164 MTGEALTAEKALEYGFVYRVAESEK---LEKTCE---------------------------------------------- 194
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 487910442 254 eqdyQAIVSLRDASSDwlrqasenlqkgspSTAAITWLLWQwgKQVHSWDEVFDLEAQISEWKIRHPDFVEGVRA 328
Cdd:PRK07260 195 ----QLLKKLRRGSSN--------------SYAAIKSLVWE--SFFKGWEDYAKLELALQESLAFKEDFKEGVRA 249
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
12-152 2.90e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 57.01  E-value: 2.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  12 PDLVVEEAKNGWRIVRLNRPkSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVrKLRQLVInqevet 91
Cdd:PRK06495   3 MSQLKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVRVVVL-TGAGKVFCAGADL-KGRPDVI------ 73
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 487910442  92 ankffqqEYALDLLLHNY------------AKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGL 152
Cdd:PRK06495  74 -------KGPGDLRAHNRrtrecfhairecAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL 139
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
11-188 3.30e-09

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 57.26  E-value: 3.30e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  11 HPDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPkAFCAGGDvrkLRQLVINQEVE 90
Cdd:PRK08139   9 EAPLLLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHD---LKEMRAARGLA 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  91 TANKFFQQEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLY---PDVGASRFLADRGQ 167
Cdd:PRK08139  85 YFRALFARCSRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVALSRNVPRKQA 164
                        170       180
                 ....*....|....*....|.
gi 487910442 168 IGLFtgLTGSIMTAAGAYSIG 188
Cdd:PRK08139 165 MEML--LTGEFIDAATAREWG 183
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
32-196 4.45e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 56.58  E-value: 4.45e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  32 KSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLvinqEVETANKFFQQEYALDLLLHNYAK 111
Cdd:PRK06143  26 GSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATL----DQASAEAFISRLRDLCDAVRHFPV 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 112 PVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLyPDV------------GASRFLAdrgqiglftgLTGSIM 179
Cdd:PRK06143 102 PVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVihaallprligwARTRWLL----------LTGETI 170
                        170
                 ....*....|....*..
gi 487910442 180 TAAGAYSIGWATHICEA 196
Cdd:PRK06143 171 DAAQALAWGLVDRVVPL 187
PLN02888 PLN02888
enoyl-CoA hydratase
14-208 7.52e-09

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 55.91  E-value: 7.52e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  14 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPkAFCAGGDVRKLRQlVINQEVET-- 91
Cdd:PLN02888  11 ILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGR-AFCSGVDLTAAEE-VFKGDVKDve 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  92 ANKFFQQEYAldlllhnyAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIGLF 171
Cdd:PLN02888  89 TDPVAQMERC--------RKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRI--IGAN 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 487910442 172 ----TGLTGSIMTAAGAYSIGWATHICEAqrDNVLQKVLNI 208
Cdd:PLN02888 159 rareVSLTAMPLTAETAERWGLVNHVVEE--SELLKKAREV 197
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
12-196 8.15e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 55.80  E-value: 8.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  12 PDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDeqVKAIWLDSTTPKaFCAGGDVRKLRQLVINQEVET 91
Cdd:PRK08150   1 PSLVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDH-FCAGLDLSELRERDAGEGMHH 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  92 ANKFFQqeyALDLLLHNyAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQIGLF 171
Cdd:PRK08150  78 SRRWHR---VFDKIQYG-RVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARM 153
                        170       180
                 ....*....|....*....|....*..
gi 487910442 172 TG--LTGSIMTAAGAYSIGWATHICEA 196
Cdd:PRK08150 154 TDmmLTGRVYDAQEGERLGLAQYLVPA 180
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
25-198 6.91e-08

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 53.11  E-value: 6.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  25 IVRLNRPKSLHALDESIVTALLRVFEDFRDDEqVKAIWLDSTT-PKAFCAGGDVRKLRQ-----LVINQEVETANKFFQQ 98
Cdd:PRK11423  16 TITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSgSKVWSAGHDIHELPSggrdpLSYDDPLRQILRMIQK 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  99 eyaldlllhnYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGL-YPDVGASRFLADRGqIGLFTGL--T 175
Cdd:PRK11423  95 ----------FPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVpYNLSGILNFTNDAG-FHIVKEMffT 163
                        170       180
                 ....*....|....*....|...
gi 487910442 176 GSIMTAAGAYSIGWATHICEAQR 198
Cdd:PRK11423 164 ASPITAQRALAVGILNHVVEVEE 186
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
14-191 1.07e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 52.38  E-value: 1.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  14 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVETAN 93
Cdd:PRK07827   7 LVRYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVL-THTGGTFCAGADLSEAGGGGGDPYDAAVA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  94 KFFQQEYALDLLLHnYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDV------------GASRF 161
Cdd:PRK07827  86 RAREMTALLRAIVE-LPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIisltllprlsprAAARY 164
                        170       180       190
                 ....*....|....*....|....*....|
gi 487910442 162 LadrgqiglftgLTGSIMTAAGAYSIGWAT 191
Cdd:PRK07827 165 Y-----------LTGEKFGAAEAARIGLVT 183
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
12-193 4.40e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 50.49  E-value: 4.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  12 PDLVVEEaKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQlviNQEVET 91
Cdd:PRK07799   5 PHALVEQ-RGHTLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKAATK---KPPGDS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  92 ANKFFQQEYALDLLL--HNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPdVGASRFLADRgQI- 168
Cdd:PRK07799  80 FKDGSYDPSRIDALLkgRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAVRLVR-QIp 157
                        170       180
                 ....*....|....*....|....*...
gi 487910442 169 ---GLFTGLTGSIMTAAGAYSIGWATHI 193
Cdd:PRK07799 158 ytvACDLLLTGRHITAAEAKEIGLIGHV 185
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
13-163 4.80e-07

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 50.62  E-value: 4.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442   13 DLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDvRKLRQlvinqevETA 92
Cdd:TIGR01929   3 DIRYEKSTDGIAKITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGD-QKVRG-------DYG 74
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487910442   93 NKFFQQEYALDLL-----LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLA 163
Cdd:TIGR01929  75 YIDDSGVHRLNVLdvqrqIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMA 150
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
26-188 8.97e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 49.97  E-value: 8.97e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  26 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKL----RQLVINQEVETANKFFQQeyA 101
Cdd:PRK06142  19 VTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVL-SGSGKHFSYGIDLPAMagvfGQLGKDGLARPRTDLRRE--I 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 102 LDL-----LLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGA------------SRFLAd 164
Cdd:PRK06142  96 LRLqaainAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSlqrlpriigdghLRELA- 174
                        170       180
                 ....*....|....*....|....
gi 487910442 165 rgqiglftgLTGSIMTAAGAYSIG 188
Cdd:PRK06142 175 ---------LTGRDIDAAEAEKIG 189
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
28-125 1.53e-06

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 49.12  E-value: 1.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  28 LNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGD--VRKLRQLVINQEVETANkffqqeyALDL- 104
Cdd:PRK07396  28 INRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDqkVRGYGGYVDDDGVPRLN-------VLDLq 100
                         90       100
                 ....*....|....*....|..
gi 487910442 105 -LLHNYAKPVVVWGEGYVMGGG 125
Cdd:PRK07396 101 rLIRTCPKPVIAMVAGYAIGGG 122
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
28-198 2.17e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 48.52  E-value: 2.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  28 LNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVI---NQEVETANKFFQQEYALDL 104
Cdd:PRK07468  20 LNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAQMTadrATRIEEARRLAMMLKALND 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 105 LlhnyAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRGQI-GLFTGLTGSIMTAAG 183
Cdd:PRK07468  99 L----PKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEAnARRVFMSARLFDAEE 174
                        170
                 ....*....|....*
gi 487910442 184 AYSIGWATHICEAQR 198
Cdd:PRK07468 175 AVRLGLLSRVVPAER 189
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
25-158 1.00e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 46.50  E-value: 1.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  25 IVRLNRPKSLHAL-DESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVETANkfFQQEYA-- 101
Cdd:PRK09245  15 TLTMNRPETRNALsDNDAVDALVAACAAINADRSVRAVIL-TGAGTAFSSGGNVKDMRARVGAFGGSPAD--IRQGYRhg 91
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 487910442 102 ---LDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYP-DVGA 158
Cdd:PRK09245  92 iqrIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPgDGGA 152
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
11-183 2.20e-05

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 45.34  E-value: 2.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  11 HPDLVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVE 90
Cdd:PRK07110   3 MKVVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVIL-TGYPNYFATGGTQEGLLSLQTGKGTF 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  91 TANKFFqqeyaldLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADRgqIGL 170
Cdd:PRK07110  82 TEANLY-------SLALNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEK--LGL 152
                        170
                 ....*....|...
gi 487910442 171 FTGLTgSIMTAAG 183
Cdd:PRK07110 153 ALGQE-MLLTARY 164
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
71-164 6.65e-05

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 43.67  E-value: 6.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  71 FCAGGDVRKLRQLViNQEVETANKFFQQeyALDLLLhNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINI 150
Cdd:PRK05869  64 FSAGDDMPELRTLS-AQEADTAARVRQQ--AVDAVA-AIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILA 139
                         90
                 ....*....|....
gi 487910442 151 GLYPDVGASRFLAD 164
Cdd:PRK05869 140 GLAPSGDGMARLTR 153
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
26-193 7.36e-05

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 43.86  E-value: 7.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  26 VRLNRPKSLHALDESIVTALLRVFEDfRDDEQVKAIWLDSTTPkAFCAGGDVrklrqlvinqevetANKFFQQEY--ALD 103
Cdd:PRK07854  13 IELQRPERRNALNAELCEELREAVRK-AVDESARAIVLTGQGT-VFCAGADL--------------SGDVYADDFpdALI 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 104 LLLHNY-AKPVVVWGE--GYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPD----------VGASR----FLADR- 165
Cdd:PRK07854  77 EMLHAIdAAPVPVIAAinGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDnwtirrlsslVGGGRaramLLGAEk 156
                        170       180       190
                 ....*....|....*....|....*....|
gi 487910442 166 --GQIGLFTGLTGSIMTAAGAysIGWATHI 193
Cdd:PRK07854 157 ltAEQALATGMANRIGTLADA--QAWAAEI 184
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
14-188 1.57e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 42.90  E-value: 1.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  14 LVVEEAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKlrqlviNQEVETAN 93
Cdd:PRK05864  11 VLVDHPRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVL-TGAGRGFSSGADHKS------AGVVPHVE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  94 KFFQQEYALD---------LLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLY-PDVGASrFLA 163
Cdd:PRK05864  84 GLTRPTYALRsmellddviLALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLS-YLL 162
                        170       180
                 ....*....|....*....|....*....
gi 487910442 164 DRGqIGLFTG----LTGSIMTAAGAYSIG 188
Cdd:PRK05864 163 PRA-IGSSRAfeimLTGRDVDAEEAERIG 190
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
25-188 2.09e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 42.69  E-value: 2.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  25 IVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYA--- 101
Cdd:PRK08260  16 TITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIV-TGAGRAFCAGADLSAGGNTFDLDAPRTPVEADEEDRAdps 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 102 ----------LDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADrgQIGLF 171
Cdd:PRK08260  95 ddgvrdgggrVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPR--LVGLQ 172
                        170       180
                 ....*....|....*....|.
gi 487910442 172 TGL----TGSIMTAAGAYSIG 188
Cdd:PRK08260 173 TALewvySGRVFDAQEALDGG 193
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
28-157 2.16e-04

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 42.58  E-value: 2.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  28 LNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLV----------INQEVETANKFFQ 97
Cdd:PLN02664  23 LNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIIL-SGAGDHFCSGIDLKTLNSISeqsssgdrgrSGERLRRKIKFLQ 101
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  98 QEYALdllLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVG 157
Cdd:PLN02664 102 DAITA---IEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLG 158
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
18-188 2.98e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 41.88  E-value: 2.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  18 EAKNGWRIVRLNRPKsLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETANKffq 97
Cdd:PRK07938   7 TPEPGIAEVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLRAEG-RGFNAGVDIKELQATPGFTALIDANR--- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  98 QEYALDLLLHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEIniglypdvgasrflaDRGQIGLFTGL--- 174
Cdd:PRK07938  82 GCFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEV---------------DRGALGAATHLqrl 146
                        170       180
                 ....*....|....*....|....*
gi 487910442 175 -----------TGSIMTAAGAYSIG 188
Cdd:PRK07938 147 vpqhlmralffTAATITAAELHHFG 171
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
24-132 4.29e-04

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 41.55  E-value: 4.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  24 RIVrLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQLVINQEVETAnkfFQQEyALD 103
Cdd:PRK07327  24 EIV-LNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDLALVEEMADDFEVRAR---VWRE-ARD 97
                         90       100       110
                 ....*....|....*....|....*....|.
gi 487910442 104 LLLH--NYAKPVVVWGEGYVMGGGLGLFMAA 132
Cdd:PRK07327  98 LVYNviNCDKPIVSAIHGPAVGAGLVAALLA 128
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
28-154 5.04e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 41.21  E-value: 5.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  28 LNRPKSLHALDESIVTALLRVFEDFRDDeqVKAIWLDSTtPKAFCAGGDVRKLRQLVINQEVETankfFQQEYALDLLLH 107
Cdd:PRK07112  19 LHRPEAQNTINDRLIAECMDVLDRCEHA--ATIVVLEGL-PEVFCFGADFSAIAEKPDAGRADL----IDAEPLYDLWHR 91
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 487910442 108 NYAKPVVVWG--EGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYP 154
Cdd:PRK07112  92 LATGPYVTIAhvRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIP 140
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
25-188 6.85e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 41.06  E-value: 6.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  25 IVRLNRPKSlHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPKAFCAGGDVRKLRQLVINQEVETANKF---FQQeya 101
Cdd:PRK09076  15 ILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFADGDKAVAREMARRFgeaFEA--- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 102 ldllLHNYaKPVVVWG-EGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLADrgqiglFTG------- 173
Cdd:PRK09076  91 ----LSAF-RGVSIAAiNGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPW------LVGegwakrm 159
                        170
                 ....*....|....*.
gi 487910442 174 -LTGSIMTAAGAYSIG 188
Cdd:PRK09076 160 iLCGERVDAATALRIG 175
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
14-159 7.70e-04

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 41.39  E-value: 7.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  14 LVVEEAKNGwrIVRL--NRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPkAFCAGGDVRKLRQL------VI 85
Cdd:PRK11730   8 LQVDWLEDG--IAELvfDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLTSAKD-AFIVGADITEFLSLfaapeeEL 84
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 487910442  86 NQEVETANKFFQQEYALDLllhnyakPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGAS 159
Cdd:PRK11730  85 SQWLHFANSIFNRLEDLPV-------PTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGT 151
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
25-78 8.98e-04

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 40.57  E-value: 8.98e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 487910442  25 IVRL--NRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTPK-----AFCAGGDVR 78
Cdd:COG0447   28 IARIaiNRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGPSkdggwAFCSGGDQR 88
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
18-188 9.89e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 40.55  E-value: 9.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  18 EAKNGWRIVRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKA-IWLDstTPKAFCAGGDVRKLrqlvinQEVETANKFF 96
Cdd:PRK06023  11 GAHPGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAhVFLG--TEGCFSAGNDMQDF------LAAAMGGTSF 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  97 QQEyALDLL--LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASrFLADR--GQIGLFT 172
Cdd:PRK06023  83 GSE-ILDFLiaLAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSS-LLAPRlmGHQRAFA 160
                        170
                 ....*....|....*..
gi 487910442 173 GLT-GSIMTAAGAYSIG 188
Cdd:PRK06023 161 LLAlGEGFSAEAAQEAG 177
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
28-156 2.58e-03

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 39.02  E-value: 2.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  28 LNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLDSTTpKAFCAGGDVRKLRQ---LVINQEVETANKFFQQEYALdl 104
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRG-RHFSAGADLAWMQQsadLDYNTNLDDARELAELMYNL-- 97
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 487910442 105 llHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDV 156
Cdd:PRK05674  98 --YRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAV 147
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
63-165 6.19e-03

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 37.97  E-value: 6.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  63 LDSTTPKAFCAGGDVRKLRQLVINQEVETAnkffqQEYA---LDLLLHNY---AKPVVVWG--EGYVMGGGLGLFMAAPF 134
Cdd:PRK08788  71 LASDVPGVFNLGGDLALFAELIRAGDRDAL-----LAYAracVDGVHAFHrgfGAGAISIAlvQGDALGGGFEAALSHHT 145
                         90       100       110
                 ....*....|....*....|....*....|.
gi 487910442 135 RLVTPYSRLAMPEINIGLYPDVGASRFLADR 165
Cdd:PRK08788 146 IIAERGAKMGFPEILFNLFPGMGAYSFLARR 176
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
26-188 8.57e-03

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 37.68  E-value: 8.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442  26 VRLNRPKSLHALDESIVTALLRVFEDFRDDEQVKAIWLdSTTPKAFCAGGDVRKLRQLVINQEVETANKFFQQEYALDLL 105
Cdd:PRK09120  21 VTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVL-TGAGDAWSAGMDLKEYFRETDAQPEILQERIRREAYGWWRR 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487910442 106 LHNYAKPVVVWGEGYVMGGGLGLFMAAPFRLVTPYSRLAMPEINIGLYPDVGASRFLAD--RGQIGLFTGLTGSIMTAAG 183
Cdd:PRK09120 100 LRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADtvGHRDALYYIMTGETFTGRK 179

                 ....*
gi 487910442 184 AYSIG 188
Cdd:PRK09120 180 AAEMG 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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