|
Name |
Accession |
Description |
Interval |
E-value |
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
23-451 |
0e+00 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 550.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 23 LGINGEGVGYFKRQVVFIPGALPGEEVVAEATKIQRGFAEAKVKKVRKSSPHRVKAPCSVYEECGGCQLQHLDYKEQLNQ 102
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 103 KRDIVVQAFEKYMNNSLEE-KIRPTLGmENPWHYRNKSQLQVGR-KDEKVITGLYKQNSHQLIDISHCMIQHKATNEATK 180
Cdd:TIGR00479 81 KQQQVIALLERIGKFVSEPiEDVPTIG-DDPWGYRNKARLSLGRsPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 181 VVRRILEKLNVSIYNEKKQKGLVRTIVTRTAVQTGEVQVTLITTKEELPNKDQFIAEVQKQMPSVKSIMQNVNWRKTSVI 260
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 261 FGDKTFKLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGNEKIVDAYCGVGTIGLWLANDAAEVRG 340
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 341 MDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPKWVKEGWRPDVIVVDPPRTGCDDKLLETILKVKPKQVVYVSCNPS 420
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 487956191 421 SLARDVETLM-ESYEVEYVQPVDMFPHTAHVE 451
Cdd:TIGR00479 400 TLARDLEALCkAGYTIARVQPVDMFPHTGHVE 431
|
|
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
14-457 |
2.79e-180 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 508.56 E-value: 2.79e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 14 QTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAEATKIQRGFAEAKVKKVRKSSPHRVKAPCSVYEECGGCQLQH 93
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 94 LDYKEQLNQKRDIVVQAFEKYMNNSLEEkIRPTLGMENPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDISHCMIQHK 173
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIGGLPEVE-VEPIIGSPEPWGYRNRARLSVRRTDGRLRLGFYARGSHELVDIDECPLLDP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 174 ATNEATKVVRRILEKLNvsiynekKQKGLVRTIVTRtavqtgevqvtlittkeelpnkdqfiaevqkqmpsvksimqnvn 253
Cdd:COG2265 160 ALNALLPALRELLAELG-------ARRGELRHLVVR-------------------------------------------- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 254 wrktsvifgdktfklAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGNEKIVDAYCGVGTIGLWLAN 333
Cdd:COG2265 189 ---------------AGRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLAR 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 334 DAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPKWVKEGwRPDVIVVDPPRTGCDDKLLETILKVKPKQVV 413
Cdd:COG2265 254 RAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELLWGG-RPDVVVLDPPRAGAGPEVLEALAALGPRRIV 332
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 487956191 414 YVSCNPSSLARDVETLMES-YEVEYVQPVDMFPHTAHVENVVKLV 457
Cdd:COG2265 333 YVSCNPATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
14-451 |
3.82e-72 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 234.28 E-value: 3.82e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 14 QTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAEATKIQRGFAEAKVKKVRKSSPHRVKAPCSVYEECGGCQLQH 93
Cdd:PRK13168 14 QIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 94 LDYKEQLNQKRDIVVQAFEKYMNNSLEEKIRPTLGmeNPWHYRNKSQLQVG--RKDEKVITGLYKQNSHQLIDISHCMIQ 171
Cdd:PRK13168 94 LSIDAQIASKQRALEDLLKHLAGVEPEEVLPPIAG--PPWGYRRRARLSVRyvPKKGQLLVGFREKNSSDIVDIDQCPVL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 172 HKATNEATKVVRRILEKLNVsiyneKKQKGLVRTIVTrtavQTGEVQVTLITtkEELPNKD-----QFIAEvqkqmpsvk 246
Cdd:PRK13168 172 VPPLSALLPPLRALLSSLSA-----KRRLGHVELAQG----DNGTALVLRHL--EPLSEADraklrAFAEQ--------- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 247 simQNVNWRktsvifgdktfkLAGKEVIQETLG--------------DLSFELSARAFFQLNPEQTVVLYDEAKKAAALT 312
Cdd:PRK13168 232 ---HGLQLY------------LQPKGPDLVHLLgpadaqlsyylpefGLRLAFSPRDFIQVNAQVNQKMVARALEWLDPQ 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 313 GNEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPK--WVKEGWrpDVIVVD 390
Cdd:PRK13168 297 PGDRVLDLFCGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDqpWALGGF--DKVLLD 374
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487956191 391 PPRTGCDDkLLETILKVKPKQVVYVSCNPSSLARDVETLMES-YEVEYVQPVDMFPHTAHVE 451
Cdd:PRK13168 375 PPRAGAAE-VMQALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHTGHVE 435
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
95-459 |
1.09e-12 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 69.00 E-value: 1.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 95 DYKEQLNQKRDIVVQAFEKYMNNSLEEKIRPtlgmenPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDISHCMIQHKA 174
Cdd:pfam05958 1 QYDAQLAEKKSRLKALFAPFYAPDPEVFASP------DKHYRMRAEFRIWHEGDDLYYAMFDQQTKSRIRVDQFPAASEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 175 TNEatkVVRRILEKL--NVSIYNEKKQKGLVRTIvtrtavqTGEVQVTLITTKeelPNKDQFIAEVQKQMPSVKSIMQNV 252
Cdd:pfam05958 75 INE---LMPALIAALrqDPALRHKLFQVDFLTTL-------SGEALVSLLYHK---QLDDEWRQAAEALRDALRAQGLDV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 253 NW----RKTSVIFG----DKTFKLAGKEVIQETLGDlsfelsarAFFQLNPEQTVVLYDEAKKAaalTGNEK--IVDAYC 322
Cdd:pfam05958 142 NLigraRKQKIVLDqdyvDETLPVAGREFIYRQVEN--------SFTQPNAAVNIKMLEWACDV---TQGSKgdLLELYC 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 323 GVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPKWVKEgwRP--------------DVIV 388
Cdd:pfam05958 211 GNGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGV--REfnrlkgidlksyncSTIF 288
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 487956191 389 VDPPRTGCDDKLLETILKVKpkQVVYVSCNPSSLARDVETLMESYEVEYVQPVDMFPHTAHVENVVKLVRK 459
Cdd:pfam05958 289 VDPPRAGLDPETLKLVQAYP--RILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
316-417 |
4.79e-09 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 53.97 E-value: 4.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 316 KIVDAYCGVGTIGLWLAND-AAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPKWVKegwRPDVIVVDPPRT 394
Cdd:cd02440 1 RVLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADE---SFDVIISDPPLH 77
|
90 100
....*....|....*....|....*..
gi 487956191 395 GCDD---KLLETILKV-KPKQVVYVSC 417
Cdd:cd02440 78 HLVEdlaRFLEEARRLlKPGGVLVLTL 104
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
23-451 |
0e+00 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 550.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 23 LGINGEGVGYFKRQVVFIPGALPGEEVVAEATKIQRGFAEAKVKKVRKSSPHRVKAPCSVYEECGGCQLQHLDYKEQLNQ 102
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 103 KRDIVVQAFEKYMNNSLEE-KIRPTLGmENPWHYRNKSQLQVGR-KDEKVITGLYKQNSHQLIDISHCMIQHKATNEATK 180
Cdd:TIGR00479 81 KQQQVIALLERIGKFVSEPiEDVPTIG-DDPWGYRNKARLSLGRsPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 181 VVRRILEKLNVSIYNEKKQKGLVRTIVTRTAVQTGEVQVTLITTKEELPNKDQFIAEVQKQMPSVKSIMQNVNWRKTSVI 260
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 261 FGDKTFKLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGNEKIVDAYCGVGTIGLWLANDAAEVRG 340
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 341 MDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPKWVKEGWRPDVIVVDPPRTGCDDKLLETILKVKPKQVVYVSCNPS 420
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 487956191 421 SLARDVETLM-ESYEVEYVQPVDMFPHTAHVE 451
Cdd:TIGR00479 400 TLARDLEALCkAGYTIARVQPVDMFPHTGHVE 431
|
|
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
14-457 |
2.79e-180 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 508.56 E-value: 2.79e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 14 QTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAEATKIQRGFAEAKVKKVRKSSPHRVKAPCSVYEECGGCQLQH 93
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 94 LDYKEQLNQKRDIVVQAFEKYMNNSLEEkIRPTLGMENPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDISHCMIQHK 173
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIGGLPEVE-VEPIIGSPEPWGYRNRARLSVRRTDGRLRLGFYARGSHELVDIDECPLLDP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 174 ATNEATKVVRRILEKLNvsiynekKQKGLVRTIVTRtavqtgevqvtlittkeelpnkdqfiaevqkqmpsvksimqnvn 253
Cdd:COG2265 160 ALNALLPALRELLAELG-------ARRGELRHLVVR-------------------------------------------- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 254 wrktsvifgdktfklAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGNEKIVDAYCGVGTIGLWLAN 333
Cdd:COG2265 189 ---------------AGRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLAR 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 334 DAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPKWVKEGwRPDVIVVDPPRTGCDDKLLETILKVKPKQVV 413
Cdd:COG2265 254 RAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELLWGG-RPDVVVLDPPRAGAGPEVLEALAALGPRRIV 332
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 487956191 414 YVSCNPSSLARDVETLMES-YEVEYVQPVDMFPHTAHVENVVKLV 457
Cdd:COG2265 333 YVSCNPATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
14-451 |
3.82e-72 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 234.28 E-value: 3.82e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 14 QTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAEATKIQRGFAEAKVKKVRKSSPHRVKAPCSVYEECGGCQLQH 93
Cdd:PRK13168 14 QIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 94 LDYKEQLNQKRDIVVQAFEKYMNNSLEEKIRPTLGmeNPWHYRNKSQLQVG--RKDEKVITGLYKQNSHQLIDISHCMIQ 171
Cdd:PRK13168 94 LSIDAQIASKQRALEDLLKHLAGVEPEEVLPPIAG--PPWGYRRRARLSVRyvPKKGQLLVGFREKNSSDIVDIDQCPVL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 172 HKATNEATKVVRRILEKLNVsiyneKKQKGLVRTIVTrtavQTGEVQVTLITtkEELPNKD-----QFIAEvqkqmpsvk 246
Cdd:PRK13168 172 VPPLSALLPPLRALLSSLSA-----KRRLGHVELAQG----DNGTALVLRHL--EPLSEADraklrAFAEQ--------- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 247 simQNVNWRktsvifgdktfkLAGKEVIQETLG--------------DLSFELSARAFFQLNPEQTVVLYDEAKKAAALT 312
Cdd:PRK13168 232 ---HGLQLY------------LQPKGPDLVHLLgpadaqlsyylpefGLRLAFSPRDFIQVNAQVNQKMVARALEWLDPQ 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 313 GNEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPK--WVKEGWrpDVIVVD 390
Cdd:PRK13168 297 PGDRVLDLFCGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDqpWALGGF--DKVLLD 374
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487956191 391 PPRTGCDDkLLETILKVKPKQVVYVSCNPSSLARDVETLMES-YEVEYVQPVDMFPHTAHVE 451
Cdd:PRK13168 375 PPRAGAAE-VMQALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHTGHVE 435
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
163-459 |
2.04e-45 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 160.42 E-value: 2.04e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 163 IDISHCMIQHKATNEATKVVRRILEKLNVSIYNEKKQKG-LVRTIVTRTAVQtGEVQVTLIT-TKEELPNKDQFIAEVQK 240
Cdd:PRK03522 22 VDLCDCPLYPASFAPVFAALKPFIARAGLTPYNVARKRGeLKYILLTESQSD-GELMLRFVLrSETKLARLRRALPWLQA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 241 QMPSVKSIMQNVNWRKTSVIFGDKTFKLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGNEKIVDA 320
Cdd:PRK03522 101 QLPQLKVISVNIQPVHMAILEGEEEIFLTEQQALPERFNGVPLFIRPQSFFQTNPAVAAQLYATARDWVRELPPRSMWDL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 321 YCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLpkwVKEGWRPDVIVVDPPRTGCDDKL 400
Cdd:PRK03522 181 FCGVGGFGLHCATPGMQLTGIEISAEAIACAKQSAAELGLTNVQFQALDSTQFA---TAQGEVPDLVLVNPPRRGIGKEL 257
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 487956191 401 LETILKVKPKQVVYVSCNPSSLARDVEtLMESYEVEYVQPVDMFPHTAHVENVVKLVRK 459
Cdd:PRK03522 258 CDYLSQMAPRFILYSSCNAQTMAKDLA-HLPGYRIERVQLFDMFPHTAHYEVLTLLVRQ 315
|
|
| meth_trns_rumB |
TIGR02085 |
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases ... |
80-458 |
4.07e-41 |
|
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases designated RumB, formerly YbjF. Members act on 23S rRNA U747 and the equivalent position in other proteobacterial species. This family is homologous to the other 23S rRNA methyltransferase RumA and to the tRNA methyltransferase TrmA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 131140 Cd Length: 374 Bit Score: 150.37 E-value: 4.07e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 80 CSVYE--ECGGCQLQHLDYKEQLNQKRDIVVQAFEKymNNSLEEKIRPTLGMENPwhYRNKSQLQVGRKDEKVITGLYKq 157
Cdd:TIGR02085 2 CAFYIqgRCRSCQWLAQPYSEQLTNKQQHLKELLAP--NATVVQWLAPVTSAEQA--FRNKAKMVVSGSVERPILGILH- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 158 NSHQLIDISHCMIQHKATNEATKVVRRILEKLNVSIYNEKKQKGLVRTIVTRTAVQTGEVQVTLITTKE-ELPNKDQFIA 236
Cdd:TIGR02085 77 RDGTPLDLCDCPLYPQSFQPVFAYLKNFIARAGLTPYNVAKKKGELKFILLTESENSGQLMLRFVLRSEtKLAQIRRALP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 237 EVQKQMPSVKSIMQNVNWRKTSVIFGDKTFKLAGKEVIQETLGDLSFELSARAFFQLNPEQTVVLYDEAKKAAALTGNEK 316
Cdd:TIGR02085 157 WLIEQLPQLEVISVNIQPVHMAILEGEEEIFLTEQQALPERFNDVPLVIRPQSFFQTNPKVAAQLYATARQWVREIPVTQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 317 IVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLpkwVKEGWRPDVIVVDPPRTGC 396
Cdd:TIGR02085 237 MWDLFCGVGGFGLHCAGPDTQLTGIEIESEAIACAQQSAQMLGLDNLSFAALDSAKFA---TAQMSAPELVLVNPPRRGI 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 487956191 397 DDKLLETILKVKPKQVVYVSCNPSSLARDVETLmESYEVEYVQPVDMFPHTAHVENVVKLVR 458
Cdd:TIGR02085 314 GKELCDYLSQMAPKFILYSSCNAQTMAKDIAEL-SGYQIERVQLFDMFPHTSHYEVLTLLVR 374
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
86-459 |
2.89e-20 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 91.81 E-value: 2.89e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 86 CGGCQLQHLDYKEQLNQKRDIVVQAFEKYMNNSLEekIRPTlgmeNPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDI 165
Cdd:PRK05031 1 MTPECLPPEQYEAQLAEKVARLKELFAPFSAPEPE--VFRS----PPSHYRMRAEFRIWHEGDDLYYAMFDQQTKQRIRI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 166 SHCMIQHKATNEATKvvrRILEKLnvsiyneKKQKGLVRTI--VTRTAVQTGEVQVTLITTKeelPNKDQFIAEVQKqmp 243
Cdd:PRK05031 75 DQFPIASELINALMP---ALLAAL-------RANPVLRHKLfqVDFLSTLSGEILVSLLYHK---KLDEEWEQAAKA--- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 244 sVKSIMQNVNW----RKTSVIFG----DKTFKLAGKEviqetlgdLSFELSARAFFQLNPEQTVVLYDEAKKAaalTGNE 315
Cdd:PRK05031 139 -LRDALFNVHLigrsRKQKIVLDqdyvDERLPVAGRE--------FIYRQVENSFTQPNAAVNEKMLEWALDA---TKGS 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 316 K--IVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAE---QWLPKwVKEGWR------- 383
Cdd:PRK05031 207 KgdLLELYCGNGNFTLALARNFRRVLATEISKPSVAAAQYNIAANGIDNVQIIRMSAEeftQAMNG-VREFNRlkgidlk 285
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 487956191 384 ---PDVIVVDPPRTGCDDKLLETILKVKpkQVVYVSCNPSSLARDVETLMESYEVEYVQPVDMFPHTAHVENVVKLVRK 459
Cdd:PRK05031 286 synFSTIFVDPPRAGLDDETLKLVQAYE--RILYISCNPETLCENLETLSQTHKVERFALFDQFPYTHHMECGVLLEKK 362
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
95-459 |
1.09e-12 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 69.00 E-value: 1.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 95 DYKEQLNQKRDIVVQAFEKYMNNSLEEKIRPtlgmenPWHYRNKSQLQVGRKDEKVITGLYKQNSHQLIDISHCMIQHKA 174
Cdd:pfam05958 1 QYDAQLAEKKSRLKALFAPFYAPDPEVFASP------DKHYRMRAEFRIWHEGDDLYYAMFDQQTKSRIRVDQFPAASEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 175 TNEatkVVRRILEKL--NVSIYNEKKQKGLVRTIvtrtavqTGEVQVTLITTKeelPNKDQFIAEVQKQMPSVKSIMQNV 252
Cdd:pfam05958 75 INE---LMPALIAALrqDPALRHKLFQVDFLTTL-------SGEALVSLLYHK---QLDDEWRQAAEALRDALRAQGLDV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 253 NW----RKTSVIFG----DKTFKLAGKEVIQETLGDlsfelsarAFFQLNPEQTVVLYDEAKKAaalTGNEK--IVDAYC 322
Cdd:pfam05958 142 NLigraRKQKIVLDqdyvDETLPVAGREFIYRQVEN--------SFTQPNAAVNIKMLEWACDV---TQGSKgdLLELYC 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 323 GVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPKWVKEgwRP--------------DVIV 388
Cdd:pfam05958 211 GNGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGV--REfnrlkgidlksyncSTIF 288
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 487956191 389 VDPPRTGCDDKLLETILKVKpkQVVYVSCNPSSLARDVETLMESYEVEYVQPVDMFPHTAHVENVVKLVRK 459
Cdd:pfam05958 289 VDPPRAGLDPETLKLVQAYP--RILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| TRAM |
pfam01938 |
TRAM domain; This small domain has no known function. However it may perform a nucleic acid ... |
9-66 |
1.62e-12 |
|
TRAM domain; This small domain has no known function. However it may perform a nucleic acid binding role (Bateman A. unpublished observation).
Pssm-ID: 396497 [Multi-domain] Cd Length: 59 Bit Score: 62.23 E-value: 1.62e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 487956191 9 KLEVGQTFPVTIKRLGINGEGVGYFKR-QVVFIPGALPGEEVVAEATKIQRGFAEAKVK 66
Cdd:pfam01938 1 RRYVGQTQEVLVEGLSSNGEGIGRTDNgKVVFVPGALPGEFVEVKITKVKRNYLRGELL 59
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
311-432 |
2.83e-10 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 58.58 E-value: 2.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 311 LTGNEKIVDAYCGVGTIGLWLA---NDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQwLPKWVKEGwRPDVI 387
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAeelGPNAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEE-LPELLEDD-KFDVV 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 487956191 388 --------VVDPprtgcdDKLLETILKVKPKQVVYVSCNPSSLARDVETLMES 432
Cdd:pfam13847 79 isncvlnhIPDP------DKVLQEILRVLKPGGRLIISDPDSLAELPAHVKED 125
|
|
| COG3269 |
COG3269 |
Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; |
2-65 |
3.02e-09 |
|
Predicted RNA-binding protein, contains TRAM domain [General function prediction only];
Pssm-ID: 442500 [Multi-domain] Cd Length: 129 Bit Score: 55.06 E-value: 3.02e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 487956191 2 IQKQQESKLEVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAEATKIQRGFAEAKV 65
Cdd:COG3269 62 EAQELTPPVEEGEEYEVEIEDIGKKGDGIARVEGFVIFVPGAEVGDRVKVKITKVKRNFAFAEV 125
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
316-417 |
4.79e-09 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 53.97 E-value: 4.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 316 KIVDAYCGVGTIGLWLAND-AAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPKWVKegwRPDVIVVDPPRT 394
Cdd:cd02440 1 RVLDLGCGTGALALALASGpGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADE---SFDVIISDPPLH 77
|
90 100
....*....|....*....|....*..
gi 487956191 395 GCDD---KLLETILKV-KPKQVVYVSC 417
Cdd:cd02440 78 HLVEdlaRFLEEARRLlKPGGVLVLTL 104
|
|
| RlmK |
COG1092 |
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ... |
306-392 |
2.39e-08 |
|
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification
Pssm-ID: 440709 [Multi-domain] Cd Length: 392 Bit Score: 55.96 E-value: 2.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 306 KKAAALTGNEKIVDAYCGVGTIGLW-LANDAAEVRGMDVIPEAIEDAKKNAKRHGFT-NAKYEAGKAEQWLPKWVKEGWR 383
Cdd:COG1092 209 ARVAELAKGKRVLNLFSYTGGFSVHaAAGGAKSVTSVDLSATALEWAKENAALNGLDdRHEFVQADAFDWLRELAREGER 288
|
....*....
gi 487956191 384 PDVIVVDPP 392
Cdd:COG1092 289 FDLIILDPP 297
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
309-392 |
2.26e-07 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 50.72 E-value: 2.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 309 AALTGNEKIVDAYCGVGTI---GLWLandAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQwLPKWVKegwRPD 385
Cdd:COG1041 22 AGAKEGDTVLDPFCGTGTIlieAGLL---GRRVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARD-LPLADE---SVD 94
|
....*..
gi 487956191 386 VIVVDPP 392
Cdd:COG1041 95 AIVTDPP 101
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
307-367 |
1.52e-06 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 48.36 E-value: 1.52e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 487956191 307 KAAALTGNEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEA 367
Cdd:PRK14968 17 ENAVDKKGDRVLEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRNNGVEV 77
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
302-375 |
6.83e-06 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 45.76 E-value: 6.83e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 487956191 302 YDEAK---KAAALTGNEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFtNAKYEAGKAEQwLP 375
Cdd:COG2226 8 YDGREallAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAED-LP 82
|
|
| PRK12336 |
PRK12336 |
translation initiation factor IF-2 subunit beta; Provisional |
2-62 |
8.77e-06 |
|
translation initiation factor IF-2 subunit beta; Provisional
Pssm-ID: 183451 [Multi-domain] Cd Length: 201 Bit Score: 46.48 E-value: 8.77e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 487956191 2 IQKQQESKLEVGQTFPVTIKRLGINGEGVGYFKRQVVFIPGALPGEEVVAEATKI--QRGFAE 62
Cdd:PRK12336 137 SSETQREAIEEGKTYEVEITGTGRKGDGVAKKGKYTIFVPGAKKGEVVKVKIKKIsgNLAFAE 199
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
295-392 |
1.77e-05 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 46.31 E-value: 1.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 295 PEqTVVLYDEAKKAAALTGNEKIVDAYCGVGTIGLWLA--NDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAK------YE 366
Cdd:PRK09328 91 PE-TEELVEWALEALLLKEPLRVLDLGTGSGAIALALAkeRPDAEVTAVDISPEALAVARRNAKHGLGARVEflqgdwFE 169
|
90 100
....*....|....*....|....*.
gi 487956191 367 AGKAEQWlpkwvkegwrpDVIVVDPP 392
Cdd:PRK09328 170 PLPGGRF-----------DLIVSNPP 184
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
311-430 |
1.96e-05 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 45.29 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 311 LTGNEKIVDAYCGVGTIGLWLAN-DAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKAEQWLPkwVKEGwRPDVIVV 389
Cdd:COG0500 24 LPKGGRVLDLGCGTGRNLLALAArFGGRVIGIDLSPEAIALARARAAKAGLGNVEFLVADLAELDP--LPAE-SFDLVVA 100
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 487956191 390 dpprTGC----DDKLLETILK-----VKPKQVVYVSCNPSSLARDVETLM 430
Cdd:COG0500 101 ----FGVlhhlPPEEREALLRelaraLKPGGVLLLSASDAAAALSLARLL 146
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
316-406 |
3.37e-05 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 44.41 E-value: 3.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 316 KIVDAYCGVGTIGLWLA--NDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGkaeqwlpkWVKEGWRP---DVIVVD 390
Cdd:COG2813 52 RVLDLGCGYGVIGLALAkrNPEARVTLVDVNARAVELARANAAANGLENVEVLWS--------DGLSGVPDgsfDLILSN 123
|
90
....*....|....*....
gi 487956191 391 PP-RTG--CDDKLLETILK 406
Cdd:COG2813 124 PPfHAGraVDKEVAHALIA 142
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
316-392 |
5.38e-05 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 43.73 E-value: 5.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 316 KIVDAYCGVGTIGLWLA--NDAAEVRGMDVIPEAIEDAKKNAKRHGFTNAKYEAGKA-EQWLPKwvkegwRPDVIVVDPP 392
Cdd:pfam05175 34 KVLDLGCGAGVLGAALAkeSPDAELTMVDINARALESARENLAANGLENGEVVASDVySGVEDG------KFDLIISNPP 107
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
322-373 |
1.27e-04 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 41.01 E-value: 1.27e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 487956191 322 CGVGTIGLWLANDA-AEVRGMDVIPEAIEDAKKNAKRHGFtNAKYEAGKAEQW 373
Cdd:pfam13649 6 CGTGRLTLALARRGgARVTGVDLSPEMLERARERAAEAGL-NVEFVQGDAEDL 57
|
|
| UPF0020 |
pfam01170 |
Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated ... |
305-395 |
3.27e-04 |
|
Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains.
Pssm-ID: 395932 [Multi-domain] Cd Length: 184 Bit Score: 41.57 E-value: 3.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 305 AKKAAAL------TGNEKIVDAYCGVGTI-------------GLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTnaky 365
Cdd:pfam01170 14 ETLAAAMvnlagwKPGDPLLDPMCGSGTIlieaalmganiapGKFDARVRAPLYGSDIDRRMVQGARLNAENAGVG---- 89
|
90 100 110
....*....|....*....|....*....|....
gi 487956191 366 EAGKAEQWLPKWVKEGWRP-DVIVVDPP---RTG 395
Cdd:pfam01170 90 DLIEFVQADAADLPLLEGSvDVIVTNPPygiRLG 123
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
308-373 |
3.59e-04 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 40.39 E-value: 3.59e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 487956191 308 AAALTGNEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHgftNAKYEAGKAEQW 373
Cdd:COG2227 19 ARLLPAGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAEL---NVDFVQGDLEDL 81
|
|
| HemK |
COG2890 |
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ... |
295-362 |
7.39e-04 |
|
Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442135 [Multi-domain] Cd Length: 282 Bit Score: 41.29 E-value: 7.39e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 295 PEqTVVLYDEAKKAAALTGNEKIVDAYCGVGTIG--LWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTN 362
Cdd:COG2890 95 PE-TEELVELALALLPAGAPPRVLDLGTGSGAIAlaLAKERPDARVTAVDISPDALAVARRNAERLGLED 163
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
308-392 |
1.13e-03 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 40.51 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 308 AAALTGNEKIVDAYCGVGTIGLWLA--NDAAEVRGMDVIPEAIEDAKKNAKRHGFTN-AKYEAGKAEQWLPKWVKEgwRP 384
Cdd:COG4123 32 FAPVKKGGRVLDLGTGTGVIALMLAqrSPGARITGVEIQPEAAELARRNVALNGLEDrITVIHGDLKEFAAELPPG--SF 109
|
....*...
gi 487956191 385 DVIVVDPP 392
Cdd:COG4123 110 DLVVSNPP 117
|
|
| Trm5 |
COG2520 |
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ... |
221-357 |
1.59e-03 |
|
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442010 [Multi-domain] Cd Length: 333 Bit Score: 40.62 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 487956191 221 LITTKEELPNKDQFIAE-VQKQMPSVKSImqnvnWRKTSVIFGD----KTFKLAGkEVIQETL----GdLSFELS-ARAF 290
Cdd:COG2520 90 IIKIPDELEEYKEEIAEaILESHPNVKTV-----LAKASGVEGEfrvpELELLAG-EGRTETIhrenG-CRFKLDvAKVY 162
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 487956191 291 FqlNPeqtvVLYDEAKKAAALTG-NEKIVDAYCGVGTIGLWLA-NDAAEVRGMDVIPEAIEDAKKNAKR 357
Cdd:COG2520 163 F--SP----RLATERLRIAELVKpGERVLDMFAGVGPFSIPIAkRSGAKVVAIDINPDAVEYLKENIRL 225
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
318-361 |
3.61e-03 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 36.49 E-value: 3.61e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 487956191 318 VDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFT 361
Cdd:pfam08241 1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLT 44
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
301-363 |
6.28e-03 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 37.67 E-value: 6.28e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 487956191 301 LYDEAKKAAALTGNEKIVDAYCGVGTIGLWLANDAAEVRGMDVIPEAIEDAKKNAKRHGFTNA 363
Cdd:COG4976 34 LAEELLARLPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKAREKGVYDRLLVA 96
|
|
| |
