|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
1-447 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 881.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 1 MSDVLADRTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLL 80
Cdd:PRK05748 1 MSEVAALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 81 EEVGGVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQ 160
Cdd:PRK05748 81 EEVGGLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDDADEILDEAEKKIFEVSERRNKSGFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 161 NIKDVLVDAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSL 240
Cdd:PRK05748 161 NIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 241 EMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQ-GLGMVLI 319
Cdd:PRK05748 241 EMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHgGLGLILI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 320 DYLQLIQGSGKSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYRE 399
Cdd:PRK05748 321 DYLQLIQGSGRSGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLYRD 400
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 488103104 400 DYYDRETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLERRFDD 447
Cdd:PRK05748 401 DYYDEETENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREED 448
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
10-442 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 761.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 10 PPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVSYL 89
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 90 AELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQNIKDVLVDA 169
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGDVEELLDEAEQKIFEIAESRTSKGFKSIKEILKEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 170 YDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGADQLVM 249
Cdd:TIGR00665 161 VEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAEQLVM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 250 RMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQLIQGSG 329
Cdd:TIGR00665 241 RMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHGLGLIVIDYLQLMSGSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 330 KSgENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRETENK 409
Cdd:TIGR00665 321 RS-ENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNPDSEDK 399
|
410 420 430
....*....|....*....|....*....|...
gi 488103104 410 NTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLE 442
Cdd:TIGR00665 400 GIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
13-442 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 736.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 13 NIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVSYLAEL 92
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 93 AEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQNIKDVLVDAYDK 172
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEALER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 173 IELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGADQLVMRML 252
Cdd:COG0305 161 IEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLVMRLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 253 CAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQLIQGSGKSg 332
Cdd:COG0305 241 SSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHGLGLIVIDYLQLMSGSGRS- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 333 ENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRETENKNTI 412
Cdd:COG0305 320 ENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPDSEDKGIA 399
|
410 420 430
....*....|....*....|....*....|
gi 488103104 413 EIIIAKQRNGPVGSVELAFVKEFNKFVNLE 442
Cdd:COG0305 400 EIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
8-442 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 536.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 8 RTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVS 87
Cdd:PRK05595 6 RSLPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEAAGGVT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 88 YLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQNIKDVLV 167
Cdd:PRK05595 86 YITELSNSIVSTANIQSYIKIVKDKSTLRRLIKSSTEIIENSYNNQDDVEKVIDSAEKKIFDISEKRTTSDFEPLSNVLE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 168 DAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGADQL 247
Cdd:PRK05595 166 RGFEQIENLFNNKGETTGVASGFRELDAKTSGFQKGDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSLEMSKEQL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 248 VMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQLIQG 327
Cdd:PRK05595 246 AYKLLCSEANVDMLRLRTGNLEDKDWENIARASGPLAAAKIFIDDTAGVSVMEMRSKCRRLKIEHGIDMILIDYLQLMSG 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 328 SGKSgENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRETE 407
Cdd:PRK05595 326 GKGS-ESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKETE 404
|
410 420 430
....*....|....*....|....*....|....*
gi 488103104 408 NKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLE 442
Cdd:PRK05595 405 DKNVAECIIAKQRNGPTGTVKLAWLGQYSKFGNLD 439
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
5-392 |
0e+00 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 535.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 5 LADRTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVG 84
Cdd:PRK07773 19 DYGRQPPQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTVAAELDRRGLLERIG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 85 GVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQNIKD 164
Cdd:PRK07773 99 GAPYLHTLISTVPTAANADYYARIVAEKALLRRLIEAGTRIVQYGYAEGADVAEVVDRAQAEIYDVTDRRLSEDFVALED 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 165 VLVDAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGA 244
Cdd:PRK07773 179 LLQPTFDEIDAIASSGGLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMGKTTFGLDFARNCAIRHRLAVAIFSLEMSK 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 245 DQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQL 324
Cdd:PRK07773 259 EQLVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARAMGEISEAPIFIDDTPNLTVMEIRAKARRLRQEANLGLIVVDYLQL 338
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488103104 325 IQGsGKSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADI 392
Cdd:PRK07773 339 MTS-GKKYENRQQEVSEISRHLKLLAKELEVPVVALSQLSRGVEQRTDKRPMLSDLRESGCLTGDTLI 405
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
185-440 |
4.50e-176 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 492.70 E-value: 4.50e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 185 GIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGADQLVMRMLCAEGNIDAQRLR 264
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 265 TGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQLIQGsGKSGENRQQEVSEISR 344
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHGLGLIVIDYLQLMSG-GSRGENRQQEISEISR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 345 TLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDREtENKNTIEIIIAKQRNGPV 424
Cdd:pfam03796 160 SLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPK-EPEGKAEIIIAKQRNGPT 238
|
250
....*....|....*.
gi 488103104 425 GSVELAFVKEFNKFVN 440
Cdd:pfam03796 239 GTVKLAFLGEYTRFEN 254
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
8-444 |
4.19e-170 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 487.08 E-value: 4.19e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 8 RTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKG---EPIDLVMMtsaMADQGLLEEVG 84
Cdd:PRK09165 19 RELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGklaTPVTLKTF---LENDEALGELG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 85 GVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGL--LNEAEKKILEVSHQ-TNAKAFQN 161
Cdd:PRK09165 96 GVQYLAKLATEAVTIINARDYGRIIYDLALRRELINIGEDVVNNAYDAPVDVAPQeqIEDAEQKLYELAETgRYEGGFQS 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 162 IKDVLVDAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVA------TKTDEN- 234
Cdd:PRK09165 176 FGTAITEAVDMANAAFKRDGHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMGKTALATNIAFNAAkayrreAQPDGSk 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 235 -------VAIFSLEMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRR 307
Cdd:PRK09165 256 kavnggvVGFFSLEMSAEQLATRILSEQSEISSSKIRRGKISEEDFEKLVDASQELQKLPLYIDDTPALSISQLRARARR 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 308 LKQEQGLGMVLIDYLQLIQGSGK-SGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSI 386
Cdd:PRK09165 336 LKRQHGLDLLVVDYLQLIRGSSKrSSDNRVQEISEITQGLKALAKELNIPVIALSQLSRQVEQRDDKRPQLSDLRESGSI 415
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488103104 387 EQDADIVAFLYREDYYDRETENK-----------------NTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLERR 444
Cdd:PRK09165 416 EQDADVVMFVYREEYYLKRKEPRegtpkheewqekmekvhNKAEVIIAKQRHGPTGTVKLAFESEFTRFGDLADR 490
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
8-441 |
4.21e-163 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 468.63 E-value: 4.21e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 8 RTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVS 87
Cdd:PRK08760 31 RVPPHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRELSEKDRPFDAVTLGEWFESQGKLEQVGDGA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 88 YLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYERED-DVDGLLNEAEKKILEVShQTNAKA---FQNIK 163
Cdd:PRK08760 111 YLIELASTTPSAANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQPEGrESIELLASAEKAVFKIA-EAGARGrtdFVAMP 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 164 DVLVDAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMG 243
Cdd:PRK08760 190 GALKDAFEELRNRFENGGNITGLPTGYNDFDAMTAGLQPTDLIILAARPAMGKTTFALNIAEYAAIKSKKGVAVFSMEMS 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 244 ADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQ 323
Cdd:PRK08760 270 ASQLAMRLISSNGRINAQRLRTGALEDEDWARVTGAIKMLKETKIFIDDTPGVSPEVLRSKCRRLKREHDLGLIVIDYLQ 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 324 LIQGSGKSgENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYD 403
Cdd:PRK08760 350 LMSVPGNS-ENRATEISEISRSLKGLAKELNVPVIALSQLNRSLETRTDKRPVMADLRESGAIEQDADMIVFIYRDDYYN 428
|
410 420 430
....*....|....*....|....*....|....*....
gi 488103104 404 RE-TENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNL 441
Cdd:PRK08760 429 KEnSPDKGLAEIIIGKHRGGPTGSCKLKFFGEYTRFDNL 467
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
8-440 |
1.03e-162 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 467.08 E-value: 1.03e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 8 RTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVS 87
Cdd:PRK07004 13 KVPPHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSGKAEEVGGLA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 88 YLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYERE-DDVDGLLNEAEKKILEVSHQ--TNAKAFQNIKD 164
Cdd:PRK07004 93 YLNALAQNTPSAANIRRYAEIVRDRAVLRRLVSVADEISADAFNPQgKEVRQLLDEAESKVFSIAEEgaRGTQGFLEIGP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 165 VLVDAYDKIELLHNQKGE--VTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEM 242
Cdd:PRK07004 173 LLTQVVERIDTLYHTANPsdVTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMGKTAFSMNIGEYVAVEYGLPVAVFSMEM 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 243 GADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQG-LGMVLIDY 321
Cdd:PRK07004 253 PGTQLAMRMLGSVGRLDQHRMRTGRLTDEDWPKLTHAVQKMSEAQLFIDETGGLNPMELRSRARRLARQCGkLGLIIIDY 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 322 LQLIQGSGkSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDY 401
Cdd:PRK07004 333 LQLMSGSS-QGENRATEISEISRSLKSLAKELDVPVIALSQLNRGLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEV 411
|
410 420 430
....*....|....*....|....*....|....*....
gi 488103104 402 YDRETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVN 440
Cdd:PRK07004 412 YNPDSPDKGTAEIIIGKQRNGPIGPVRLTFLGQYTKFDN 450
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
185-440 |
9.37e-156 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 441.18 E-value: 9.37e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 185 GIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGADQLVMRMLCAEGNIDAQRLR 264
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 265 TGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQG-LGMVLIDYLQLIQGSGKSgENRQQEVSEIS 343
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGgLGLIVIDYLQLIRGSKRA-ENRQQEVAEIS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 344 RTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRETENKNTIEIIIAKQRNGP 423
Cdd:cd00984 160 RSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGP 239
|
250
....*....|....*..
gi 488103104 424 VGSVELAFVKEFNKFVN 440
Cdd:cd00984 240 TGTVYLAFNPEYTRFTD 256
|
|
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
8-443 |
7.35e-150 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 435.81 E-value: 7.35e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 8 RTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVS 87
Cdd:PRK05636 68 RQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEIDPVIVAGRLDRTNDLERVGGAP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 88 YLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYERED--DVDGLLNEAEKKILEVSHQTNAKAFQNIKDV 165
Cdd:PRK05636 148 YLHTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEGDEgaEIDSVIDRAQQEVFAVSQKNQSEDYAVLADI 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 166 LVDAYDKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGAD 245
Cdd:PRK05636 228 LDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTLALDFMRSASIKHNKASVIFSLEMSKS 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 246 QLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQLI 325
Cdd:PRK05636 308 EIVMRLLSAEAEVRLSDMRGGKMDEDAWEKLVQRLGKIAQAPIFIDDSANLTMMEIRSKARRLKQKHDLKLIVVDYLQLM 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 326 QgSGKSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRE 405
Cdd:PRK05636 388 S-SGKRVESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQDKD 466
|
410 420 430
....*....|....*....|....*....|....*...
gi 488103104 406 TENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLER 443
Cdd:PRK05636 467 DERAGEADIILAKHRGGPIDTVQVAHQLHYSRFVDMAR 504
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
10-449 |
2.05e-148 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 430.96 E-value: 2.05e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 10 PPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVSYL 89
Cdd:PRK06904 23 PPHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQALKTKGKSDEVGGFAYL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 90 AELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYE-REDDVDGLLNEAEKKILEVSHQ--TNAKAFQNIKDVL 166
Cdd:PRK06904 103 AELSNNTPSAANILAYADIVREKAILRELISVGNNIAKNAYSpKGQDIKDILDEAERDVFSIAEKrtTANEGPQNVINLL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 167 VDAYDKIELLHNQKGE--VTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGA 244
Cdd:PRK06904 183 ENTIDKIENLAATPTNngVTGVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEKPVLVFSLEMPA 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 245 DQLVMRMLCAEGNIDAQRLRTGS-LTSDDWAKLTMAMGSLSN-AGIYIDDTPGIKVNEIRAKCRRLKQEQ-GLGMVLIDY 321
Cdd:PRK06904 263 EQIMMRMLASLSRVDQTKIRTGQnLDQQDWAKISSTVGMFKQkPNLYIDDSSGLTPTELRSRARRVYRENgGLSLIMVDY 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 322 LQLIQGSGKSgENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDY 401
Cdd:PRK06904 343 LQLMRAPGFE-DNRTLEIAEISRSLKALAKELKVPVVALSQLNRTLENRGDKRPVNSDLRESGSIEQDADLIMFIYRDEV 421
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 488103104 402 YDRETE-NKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNL--ERRFDDGH 449
Cdd:PRK06904 422 YNETTEdNKGVAEIIIGKQRNGPIGRVRLAFQGQYSRFDNLanIPQYYDKY 472
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
2-447 |
3.53e-146 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 425.17 E-value: 3.53e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 2 SDVLADRTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLE 81
Cdd:PRK08840 12 AQVDAIKVPPHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLERREQLE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 82 EVGGVSYLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYERED-DVDGLLNEAEKKILEVSHQ--TNAKA 158
Cdd:PRK08840 92 DVGGFAYLADLAKNTPSAANINAYADIVAERALVRNLIGVANEIADAGYDPQGrTSEDLLDMAESKVFAIAEArtSENEG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 159 FQNIKDVLVDAYDKIELLHN--QKGeVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVA 236
Cdd:PRK08840 172 PQNVDSILEKTLERIELLYKtpQDG-VTGVDTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMDQDKPVL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 237 IFSLEMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSL-SNAGIYIDDTPGIKVNEIRAKCRRLKQEQ-GL 314
Cdd:PRK08840 251 IFSLEMPAEQLMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGILmEKKNMYIDDSSGLTPTEVRSRARRIAREHgGL 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 315 GMVLIDYLQLIQGSGKSgENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVA 394
Cdd:PRK08840 331 SMIMVDYLQLMRVPALS-DNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIM 409
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 488103104 395 FLYREDYYDRETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLE-RRFDD 447
Cdd:PRK08840 410 FIYRDEVYNPDSPLKGTAEIIIGKQRNGPIGSVRLTFQGQYSRFDNYAgPAFDD 463
|
|
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
8-440 |
9.34e-145 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 421.72 E-value: 9.34e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 8 RTPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVS 87
Cdd:PRK08006 25 KVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 88 YLAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYERED-DVDGLLNEAEKKILEVSHQTNAK--AFQNIKD 164
Cdd:PRK08006 105 YLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGYDPQGrTSEDLLDLAESRVFQIAESRANKdeGPKNIAD 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 165 VLVDAYDKIELLHNQKGE-VTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMG 243
Cdd:PRK08006 185 ILDATVARIEQLFQQPHDgVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMLQDKPVLIFSLEMP 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 244 ADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSL-SNAGIYIDDTPGIKVNEIRAKCRRLKQEQ-GLGMVLIDY 321
Cdd:PRK08006 265 GEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGTMGILlEKRNMYIDDSSGLTPTEVRSRARRIFREHgGLSLIMIDY 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 322 LQLIQGSGKSgENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDY 401
Cdd:PRK08006 345 LQLMRVPSLS-DNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEV 423
|
410 420 430
....*....|....*....|....*....|....*....
gi 488103104 402 YDRETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVN 440
Cdd:PRK08006 424 YHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDN 462
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
12-439 |
6.71e-140 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 409.40 E-value: 6.71e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 12 HNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEvggvsylAE 91
Cdd:PRK08506 5 YDLDIERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKDKKIDE-------EI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 92 LAEVVPTA--ANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQNIKDVLVDA 169
Cdd:PRK08506 78 LLEILATNpiDNIEAYVEEIKEKSIKRELLSLANTIPEQAVEEDQKSSDILDEVERELYSITNGSNSEDFKDSKEVIEST 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 170 YDKIELLHNQKG-EVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVaTKTDENVAIFSLEMGADQLV 248
Cdd:PRK08506 158 MEHIKKQKRLGNkDIIGLDTGFVELNKMTKGFNKGDLIIIAARPSMGKTTLCLNMALKA-LNQDKGVAFFSLEMPAEQLM 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 249 MRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLK-QEQGLGMVLIDYLQLIQG 327
Cdd:PRK08506 237 LRMLSAKTSIPLQNLRTGDLDDDEWERLSDACDELSKKKLFVYDSGYVNIHQVRAQLRKLKsQHPEIGLAVIDYLQLMSG 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 328 SGKSGEnRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYdRETE 407
Cdd:PRK08506 317 SGNFKD-RHLQISEISRGLKLLARELDIPIIALSQLNRSLESRADKRPMLSDLRESGAIEQDADIILFVYRDDVY-KERE 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 488103104 408 NKNTI-----------------------EIIIAKQRNGPVGSVELAFVKEFNKFV 439
Cdd:PRK08506 395 EKEKEkkakkegkeerrihfqnksieeaEIIIGKNRNGPTGTVKLRFQKEFTRFV 449
|
|
| phage_DnaB |
TIGR03600 |
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or ... |
13-431 |
3.49e-138 |
|
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 274672 [Multi-domain] Cd Length: 420 Bit Score: 402.94 E-value: 3.49e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 13 NIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVSYLAEL 92
Cdd:TIGR03600 1 SIEAEQAVLGGLLLDNDFIERVMAILKPEHFYSQDHRIIFEAMLDMFAENRPVDPLTLADKLEAEGEAEKVGGLAYLAEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 93 AEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYERED-DVDGLLNEAEKKILEVSHQTNAK-AFQNIKDVLVDAY 170
Cdd:TIGR03600 81 SNNTPSAANISSYARIVREKAKERKLIAACQRIITLACSPDGgTAEQKVEEAQAALLALTMSDGQEdGFVTFGEVLEDVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 171 DKIELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGADQLVMR 250
Cdd:TIGR03600 161 RDLDKRFNPKGELTGLSTGLPKLDRLTNGLVKGDLIVIGARPSMGKTTLALNIAENVALREGKPVLFFSLEMSAEQLGER 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 251 MLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQE-QGLGMVLIDYLQLIQGSg 329
Cdd:TIGR03600 241 LLASKSGINTGNIRTGRFNDSEFNRLLNAVDRLSEKDLYIDDTGGLTVAQIRSIARRIKRKkGGLDLIVVDYIQLMAPA- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 330 kSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRETENK 409
Cdd:TIGR03600 320 -RGRDRNEELGGISRGLKALAKELDVPVVLLAQLNRGSEKRTDKRPIMSDLRDSGAIEQDADVIGLIHREGYYDAREPPA 398
|
410 420
....*....|....*....|..
gi 488103104 410 NTIEIIIAKQRNGPVGSVELAF 431
Cdd:TIGR03600 399 GIAELILAKNRHGPTGTVELLF 420
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
9-440 |
7.69e-137 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 401.53 E-value: 7.69e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 9 TPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVSY 88
Cdd:PRK06321 15 SPPNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDVHLAGEELKRRNQLNVIGGPSY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 89 LAELAEVVPTAANVEYYARIIAEKALLRRLIRTATHIVSDGYEREDDVDGLLNEAEKKILEVSHQTNAKAFQNIKDVL-- 166
Cdd:PRK06321 95 LITLAEFAGTSAYIEEYAEIIRSKSILRKMIQTAKEIEKKALEEPKDVATALDEAQNLLFKISQTTNLAQYVLVADKLkg 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 167 -VDAYDKIELLHNQKGE--------------VTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNVATKT 231
Cdd:PRK06321 175 lTSSKDKPFLLQLQERQeafqqsaqgdsspmISGIPTHFIDLDKMINGFSPSNLMILAARPAMGKTALALNIAENFCFQN 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 232 DENVAIFSLEMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQE 311
Cdd:PRK06321 255 RLPVGIFSLEMTVDQLIHRIICSRSEVESKKISVGDLSGRDFQRIVSVVNEMQEHTLLIDDQPGLKITDLRARARRMKES 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 312 QGLGMVLIDYLQLIQGSG--KSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQD 389
Cdd:PRK06321 335 YDIQFLIIDYLQLLSGSGnlRNSESRQTEISEISRMLKNLARELNIPILCLSQLSRKVEDRANHRPMMSDLRESGSIEQD 414
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 488103104 390 ADIVAFLYREDYYDrETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVN 440
Cdd:PRK06321 415 SDLVMFLLRREYYD-PNDKPGTAELIVAKNRHGSIGSVPLVFEKEFARFRN 464
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
13-442 |
8.15e-136 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 397.40 E-value: 8.15e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 13 NIEAEQAVLGAILIDQDALTSASelLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMaDQGLLEEVGGVSYLAEL 92
Cdd:PRK06749 5 NVEAEKTVLGSLLLDGELIKECR--LTEQYFSMPVHKSIFQLMRKMEDEGQPIDLVTFTSRV-DPNFLKGIGGMEYFIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 93 AEVVPTAANVEYYARIIAEKALLRRlirtATHIVSDGYER--EDDVDGLLNEAEKKILEVSHQTNAKAFqNIKDVLVDAY 170
Cdd:PRK06749 82 MDGVPTTSNFSYYEGLVRGAWKMYQ----AGVLGHKMGERliAEKSEKIIGETITALCELEEKDCVCEF-DLKDALVDLY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 171 dkiELLHNQKGEVTGIPTGFTELDKMTAGFQRNDLIIVAARPSVGKTAFSLNIAQNvATKTDENVAIFSLEMGADQLVMR 250
Cdd:PRK06749 157 ---EELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLH-AAKSGAAVGLFSLEMSSKQLLKR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 251 MLCAEGNIDAQRLRTGS--LTSDDWAKLTMAMGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLI--DYLQLIQ 326
Cdd:PRK06749 233 MASCVGEVSGGRLKNPKhrFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKILIivDYLQLIT 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 327 GSGKSGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDRET 406
Cdd:PRK06749 313 GDPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKET 392
|
410 420 430
....*....|....*....|....*....|....*.
gi 488103104 407 ENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLE 442
Cdd:PRK06749 393 MQKEMTEIHVAKHRNGPVGSFKLRFLKEFGRFVEGG 428
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
9-111 |
6.08e-40 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 138.91 E-value: 6.08e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 9 TPPHNIEAEQAVLGAILIDQDALTSASELLVPDSFYRTKHQKIFEVMLGLSDKGEPIDLVMMTSAMADQGLLEEVGGVSY 88
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|...
gi 488103104 89 LAELAEVVPTAANVEYYARIIAE 111
Cdd:pfam00772 81 LAELAANVPSAANIEYYARIVKE 103
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
379-443 |
1.74e-18 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 88.27 E-value: 1.74e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488103104 379 DIRESGSIEQDADIVAFLYREDYYDRETENKNTIEIIIAKQRNGPVGSVELAFVKEFNKFVNLER 443
Cdd:PRK07773 821 GIIVHNSIEQDADVVILLYRPDYYDRDDPRGGEAEFIVAKHRNGPTGTVTLAFQLHLSRFANLAR 885
|
|
| RecA-like_Gp4D_helicase |
cd19483 |
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the ... |
206-422 |
1.39e-17 |
|
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the RecA-like domain of the Gp4D fragment of the Gene4 helicase-primase (Gp4) from bacteriophage T7. Gp4D (residues 241-566) is the minimal fragment of the Gp4 that forms hexameric rings, it contains the helicase domain and the linker connecting the helicase and primase domains. Helicases are ring-shaped oligomeric enzymes that unwind DNA at the replication fork; they couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410891 [Multi-domain] Cd Length: 231 Bit Score: 81.46 E-value: 1.39e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 206 IIVAARPSVGKTAFSLNIAQNVATKTDENVAIFSLEMGADQLVMRMLCAEGNIDAQRLRTGSLTSDDWAKLTMAMGSLSN 285
Cdd:cd19483 1 VTIGAGSGIGKSTIVRELAYHLITEHGEKVGIISLEESVEETAKGLAGKHLGKPEPLELPRDDITEEEEDDAFDNELGSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 286 AGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQ-LIQGSGKSGENRQQEvsEISRTLKGIARELQVPVIALSQLS 364
Cdd:cd19483 81 RFFLYDHFGSLDWDNLKEKIRYMVKVLGCKVIVLDHLTiLVSGLDSSDERKELD--EIMTELAALVKELGVTIILVSHLR 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488103104 365 R---GVESRQDKRPMMSDIRESGSIEQDADIVAFLYREDYYDREtENKNTIEIIIAKQRNG 422
Cdd:cd19483 159 RpggGKGHEEGGEVSESDLRGSSAIAQLSDYVIGLERNKQADDP-VERNTTRVRVLKNRFT 218
|
|
| PRK05973 |
PRK05973 |
replicative DNA helicase; Provisional |
204-381 |
8.43e-10 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168322 [Multi-domain] Cd Length: 237 Bit Score: 58.89 E-value: 8.43e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 204 DLIIVAARPSVGKTAFSLNIAQnVATKTDENVAIFSLEMGADQLVMRmLCAegnIDAQRLRTGSL----TSDDwakltma 279
Cdd:PRK05973 65 DLVLLGARPGHGKTLLGLELAV-EAMKSGRTGVFFTLEYTEQDVRDR-LRA---LGADRAQFADLfefdTSDA------- 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 280 mgsLSNAgiYIddtpgikvneirakCRRLKQEQGLGMVLIDYLQLIQgsgksgENRQQ-EVSEISRTLKGIARELQVPVI 358
Cdd:PRK05973 133 ---ICAD--YI--------------IARLASAPRGTLVVIDYLQLLD------QRREKpDLSVQVRALKSFARERGLIIV 187
|
170 180
....*....|....*....|...
gi 488103104 359 ALSQLSRGVESRQDKRPMMSDIR 381
Cdd:PRK05973 188 FISQIDRSFDPSAKPLPDIRDVR 210
|
|
| 41 |
PHA02542 |
41 helicase; Provisional |
186-420 |
7.79e-09 |
|
41 helicase; Provisional
Pssm-ID: 222864 [Multi-domain] Cd Length: 473 Bit Score: 57.38 E-value: 7.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 186 IPTGFTELDKMT-AGFQRNDLIIVAARPSVGKTAFSLNIAQNVATkTDENVAIFSLEMGADqlvmrmLCAEgNIDAQRLR 264
Cdd:PHA02542 172 IPFKLEILNKITkGGAERKTLNVLLAGVNVGKSLGLCSLAADYLQ-QGYNVLYISMEMAEE------VIAK-RIDANLLD 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 265 tgsLTSDDWAKLTMA-----MGSLSN---AGIYIDDTP--GIKVNEIRAKCRRLKQEQGL--GMVLIDYLQLIQGS--GK 330
Cdd:PHA02542 244 ---VSLDDIDDLSKAeykakMEKLRSktqGKLIIKQYPtgGAHAGHFRALLNELKLKKNFkpDVIIVDYLGICASSrlRV 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 331 SGENRQQEVSEISRTLKGIARELQVPVIALSQLSRGVESRQDkrPMMSDIRESGSIEQDAD-IVAFLYRED--------- 400
Cdd:PHA02542 321 SSENSYTYVKAIAEELRGLAVEHDVVVWTAAQTTRSGWDSSD--VDMSDTAESAGLPATADfMLAVIETEElaqmgqqlv 398
|
250 260
....*....|....*....|....*.
gi 488103104 401 ------YYDRETENKNTIEIIIAKQR 420
Cdd:PHA02542 399 kqlksrYGDKNKFNKFLMGVDKGNQR 424
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
186-415 |
2.23e-08 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 54.54 E-value: 2.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 186 IPTGFTELDKMTA-GFQRNDLIIVAARPSVGKTAFSLNIAQNVAtKTDENVAIFSLEMGADQLVMRMlcAEGNIDAQRLr 264
Cdd:COG0467 2 VPTGIPGLDELLGgGLPRGSSTLLSGPPGTGKTTLALQFLAEGL-RRGEKGLYVSFEESPEQLLRRA--ESLGLDLEEY- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 265 tgsltsddwakltMAMGSLsnagIYIDDTP---GIKVNEIRAKCRRLKQEQGLGMVLIDYLQLIQGSGKSGENRQQEVSE 341
Cdd:COG0467 78 -------------IESGLL----RIIDLSPeelGLDLEELLARLREAVEEFGAKRVVIDSLSGLLLALPDPERLREFLHR 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 488103104 342 ISRTLKgiarELQVPVIALSQLsrgvesrqdkrPMMSDIRESGSIEQDADIVAFLyreDYYDRETENKNTIEII 415
Cdd:COG0467 141 LLRYLK----KRGVTTLLTSET-----------GGLEDEATEGGLSYLADGVILL---RYVELGGELRRALSVL 196
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
186-423 |
6.17e-08 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 53.04 E-value: 6.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 186 IPTGFTELDKMT-AGFQRNDLIIVAARPSVGKTAFSLNIAQNvATKTDENVAIFSLEMGADQLVMRMLCAEGNIDAQRLR 264
Cdd:cd01124 1 VKTGIPGLDELLgGGIPKGSVTLLTGGPGTGKTLFGLQFLYA-GAKNGEPGLFFTFEESPERLLRNAKSFGWDFDEMEDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 265 tgsltsddwakltmamGSLSNAGIYIDDTPGIKVNEIRAKCRRLKQEQGLGMVLIDYLQLIQgSGKSGENRQQevsEISR 344
Cdd:cd01124 80 ----------------GKLIIVDAPPTEAGRFSLDELLSRILSIIKSFKAKRVVIDSLSGLR-RAKEDQMRAR---RIVI 139
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488103104 345 TLKGIARELQVPVIALSQLsRGVESRQDKRPmmsdiresGSIEQDADIVAFLYredYYDRETENKNTIEIIiaKQRNGP 423
Cdd:cd01124 140 ALLNELRAAGVTTIFTSEM-RSFLSSESAGG--------GDVSFIVDGVILLR---YVEIEGELRRTIRVL--KMRGTG 204
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
202-446 |
7.76e-08 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 53.75 E-value: 7.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 202 RNDLIIVAARPSVGKTAFSLNIAQNVATKTD--------ENVAIFSLEMGADQLVMRMlcaegniDAQRLRTGSLTSDDW 273
Cdd:COG3598 12 EGGVTLLAGPPGTGKSFLALQLAAAVAAGGPwlgrrvppGKVLYLAAEDDRGELRRRL-------KALGADLGLPFADLD 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 274 AKLTMAmgslsNAGIYIDDTPGIKvnEIRAKCRrlkqEQGLGMVLIDYLQ-LIQGsgksGENRQQEVSEISRTLKGIARE 352
Cdd:COG3598 85 GRLRLL-----SLAGDLDDTDDLE--ALERAIE----EEGPDLVVIDPLArVFGG----DENDAEEMRAFLNPLDRLAER 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 353 LQVPVIALSQLSRGvesrQDKRPMMSDIRESGSIEQDADIVAFLYREdyydretENKNTIEIIIAKQRNGP-------VG 425
Cdd:COG3598 150 TGAAVLLVHHTGKG----GAGKDSGDRARGSSALRGAARSVLVLSRE-------KGEDLRVLTRAKSNYGPeialrwdNG 218
|
250 260
....*....|....*....|.
gi 488103104 426 SVELAFVKEFNKFVNLERRFD 446
Cdd:COG3598 219 GRLALEEVAALTAGAGEVELK 239
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
205-366 |
2.18e-06 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 48.15 E-value: 2.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 205 LIIVAARPSVGKTAFSLNIAQNVATKTDE----------NVAIFSLEMGADQLVMRMLCAEGNIDAqrlrtgsltsDDWA 274
Cdd:pfam13481 35 LGLLAGAPGTGKTTLALDLAAAVATGKPWlggprvpeqgKVLYVSAEGPADELRRRLRAAGADLDL----------PARL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488103104 275 KLTMAMGSLSnagIYIDDTPGIKVNE-IRAKCRRLKQEQGLGMVLIDYLQLIQGsgkSGENRQQEVSEISRTLKGIAREL 353
Cdd:pfam13481 105 LFLSLVESLP---LFFLDRGGPLLDAdVDALEAALEEVEDPDLVVIDPLARALG---GDENSNSDVGRLVKALDRLARRT 178
|
170
....*....|...
gi 488103104 354 QVPVIALSQLSRG 366
Cdd:pfam13481 179 GATVLLVHHVGKD 191
|
|
| KaiC_C |
cd19484 |
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most ... |
186-251 |
9.07e-03 |
|
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410892 [Multi-domain] Cd Length: 218 Bit Score: 37.69 E-value: 9.07e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488103104 186 IPTGFTELDKMTA--GFQRNDLIIVAARPSVGKTAFSLNIAQNvATKTDENVAIFSLEMGADQLVMRM 251
Cdd:cd19484 1 ISTGIPRLDAMLGggGFFRGSSILVSGATGTGKTLLAASFADA-ACRRGERCLYFAFEESPAQLIRNA 67
|
|
| |
