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Conserved domains on  [gi|488146367|ref|WP_002217575|]
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MULTISPECIES: RnfH family protein [Neisseria]

Protein Classification

RnfH family protein( domain architecture ID 10006787)

RnfH family protein, a member of the ubiquitin superfamily, is involved in transporting electrons for various reductive reactions such as nitrogen fixation and may also play a role in the SmpB-tmRNA-based tagging and degradation system of bacteria

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PasI COG2914
Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH ...
 1-86 9.32e-45

Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily [Defense mechanisms];


:

Pssm-ID: 442158  Cd Length: 92  Bit Score: 139.10  E-value: 9.32e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488146367  1 MLEIEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPK 80
Cdd:COG2914   4 MIRVEVAYALPDKQVLLRLEVPEGTTVEQAIEASGILERFPEIDLAKNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPK 83


                ....*.
gi 488146367 81 EARRKR 86
Cdd:COG2914  84 EARRRR 89
 
Name Accession Description Interval E-value
PasI COG2914
Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH ...
 1-86 9.32e-45

Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily [Defense mechanisms];


Pssm-ID: 442158  Cd Length: 92  Bit Score: 139.10  E-value: 9.32e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488146367  1 MLEIEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPK 80
Cdd:COG2914   4 MIRVEVAYALPDKQVLLRLEVPEGTTVEQAIEASGILERFPEIDLAKNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPK 83


                ....*.
gi 488146367 81 EARRKR 86
Cdd:COG2914  84 EARRRR 89
Ub-RnfH pfam03658
RnfH family Ubiquitin; A member of the RnfH family of the ubiquitin superfamily. Members of ...
 4-84 3.04e-41

RnfH family Ubiquitin; A member of the RnfH family of the ubiquitin superfamily. Members of this family strongly co-occur in two distinct gene neighborhood contexts. In one it is associated with a START domain protein, a membrane protein SmpA and the transfer mRNA binding protein SmpB. This association suggests a possible role in the SmpB-tmRNA-based tagging and degadation system of bacteria, which is interesting given that other members of the ubiquitin system are analogously involved in protein-tagging and degradation across eukaryotes and various prokaryotes. The second context in which the RnfH genes are present is in a membrane associated complex involved in transporting electrons for various reductive reactions such as nitrogen fixation.


Pssm-ID: 427429  Cd Length: 83  Bit Score: 129.86  E-value: 3.04e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488146367   4 IEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPKEAR 83
Cdd:pfam03658  3 VEVAYALPDRQVLLKLEVPEGATVEQAIEASGILERFPEIDLATNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPKEAR 82


                 .
gi 488146367  84 R 84
Cdd:pfam03658 83 R 83
PRK01777 PRK01777
RnfH family protein;
1-86 5.56e-35

RnfH family protein;


Pssm-ID: 234982  Cd Length: 95  Bit Score: 114.69  E-value: 5.56e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488146367  1 MLEIEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPK 80
Cdd:PRK01777  3 KIRVEVVYALPERQYLQRLTLQEGATVEEAIRASGLLELRTDIDLAKNKVGIYSRPAKLTDVLRDGDRVEIYRPLLADPK 82


                ....*.
gi 488146367 81 EARRKR 86
Cdd:PRK01777 83 ELRRKR 88
 
Name Accession Description Interval E-value
PasI COG2914
Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH ...
 1-86 9.32e-45

Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily [Defense mechanisms];


Pssm-ID: 442158  Cd Length: 92  Bit Score: 139.10  E-value: 9.32e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488146367  1 MLEIEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPK 80
Cdd:COG2914   4 MIRVEVAYALPDKQVLLRLEVPEGTTVEQAIEASGILERFPEIDLAKNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPK 83


                ....*.
gi 488146367 81 EARRKR 86
Cdd:COG2914  84 EARRRR 89
Ub-RnfH pfam03658
RnfH family Ubiquitin; A member of the RnfH family of the ubiquitin superfamily. Members of ...
 4-84 3.04e-41

RnfH family Ubiquitin; A member of the RnfH family of the ubiquitin superfamily. Members of this family strongly co-occur in two distinct gene neighborhood contexts. In one it is associated with a START domain protein, a membrane protein SmpA and the transfer mRNA binding protein SmpB. This association suggests a possible role in the SmpB-tmRNA-based tagging and degadation system of bacteria, which is interesting given that other members of the ubiquitin system are analogously involved in protein-tagging and degradation across eukaryotes and various prokaryotes. The second context in which the RnfH genes are present is in a membrane associated complex involved in transporting electrons for various reductive reactions such as nitrogen fixation.


Pssm-ID: 427429  Cd Length: 83  Bit Score: 129.86  E-value: 3.04e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488146367   4 IEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPKEAR 83
Cdd:pfam03658  3 VEVAYALPDRQVLLKLEVPEGATVEQAIEASGILERFPEIDLATNKVGIFGKLVKLDTVLRDGDRVEIYRPLIADPKEAR 82


                 .
gi 488146367  84 R 84
Cdd:pfam03658 83 R 83
PRK01777 PRK01777
RnfH family protein;
1-86 5.56e-35

RnfH family protein;


Pssm-ID: 234982  Cd Length: 95  Bit Score: 114.69  E-value: 5.56e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488146367  1 MLEIEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLNLHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPK 80
Cdd:PRK01777  3 KIRVEVVYALPERQYLQRLTLQEGATVEEAIRASGLLELRTDIDLAKNKVGIYSRPAKLTDVLRDGDRVEIYRPLLADPK 82


                ....*.
gi 488146367 81 EARRKR 86
Cdd:PRK01777 83 ELRRKR 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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