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Conserved domains on  [gi|488147709|ref|WP_002218917|]
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TonB-dependent hemoglobin receptor HmbR [Neisseria meningitidis]

Protein Classification

porin family protein; TonB-dependent siderophore receptor( domain architecture ID 11493164)

porin family protein is a member of a large superfamily consisting of classical (gram-negative ) porins which are non-specific channels for small hydrophillic molecules, maltoporin-like channels which have specificities for various sugars, and ligand-gated protein channels which cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force| TonB-dependent siderophore receptor acts as a channel to allow import of extracellular nutrients such as iron-siderophore complexes; similar to Pseudomonas aeruginosa type II pyoverdine receptor FpvAII

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 29-791 0e+00

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


:

Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 644.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   29 TETTPVKAEIKAVRvkGQRNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGR-HQKGFAVRGVEGNRVGVSIDG 107
Cdd:TIGR01786   3 ITVTATRTADPQRR--DLSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVVEGGRgGSQGINIRGLDKNRVAVLVDG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  108 VNLPDSEENSLYARYGnfnssRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDLLLDDRQFGVMMKNGYST 187
Cdd:TIGR01786  81 IRQNTSYGGQGSTFYA-----INSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLGYSS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  188 RNREWTNTLGFGVSNDRVDAALLYSQRRGHETESAGNRGYavegegsganIRGSARGIPDSSKHKYHSFLGKIAYQINDN 267
Cdd:TIGR01786 156 ANNRFTQSVAAAGRNDDVDALVQATYRRGHELKNGNKANI----------GNESKRSKPNPSDYKSQSFLAKLGWQLNDA 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  268 HRIGASLNGQQGHNYTVEESY----------NLTASSWREADDVNRRRNANLFYEWMPDSNWLSSLKADFDYQKTKVAAV 337
Cdd:TIGR01786 226 HRLGLSLEYTQTDYDEPEMTNtsyltkplgaPLLSSTVVLGDSKTRDRRTGLDYELNPDNSWLDTVKLALDKQYIQLYNY 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  338 NNKGSFPmDYSTWTRNYNQKDLDEIYNRSMDTRFKRfTLRLDSHPLQLGGGRHRLSFKTFVSRRDFENLNRDDYYFSGrv 417
Cdd:TIGR01786 306 LNATSAS-DYPGVDKNGRYKDKYDYYTLGFDTNNKI-EFSVHSLSLTYGLDRFKDKVSTGDSRRNLPTAAYNLYGYEG-- 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  418 vrttssIQHPVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQElnaecHACDKTPPAANTYKGWSGFVGLAAQLNQ 497
Cdd:TIGR01786 382 ------ENRPVKGSNFGLFLQDNIKLGDWLSLSAGLRYDHYKTDPKA-----DESKDYGAISKTYSRWSPSLGLTYKPTP 450

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  498 AWHVGYDITSGYRVPNASEVYFTYNHGSG---NWLPNPNLKAERSTTHTLSLQGRSEKGMLDANLYQSNYRNFLSEEQKL 574
Cdd:TIGR01786 451 WLTLYYSYSQGFRAPSFDELYGTGAHPGGgpyTFLPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGIGV 530

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  575 TTSGtpgctEENAYYGICSDPYkekldwqmKNIDKARIRGIELTGRLNVDKVASFvPEGWKLFGSLGYAKSKLSGDNSLL 654
Cdd:TIGR01786 531 TAKG-----NMAQVGSNTITNY--------VNIDNARIRGIELSGRYDLGSFFSG-PDGWTTTLKYGYTKGKDSDTNPWL 596

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  655 -STQPLKVIAGIDYESPSEKWGVFSRLTYLGAKKAKDAQYTVYENkgwgtplQKKVKDYPWLNKSAYVFDMYGFYKPAKN 733
Cdd:TIGR01786 597 nAITPLKVVLGLGYDHPDEKWGVGLTLTFSGAKDAVDAYATYYEN-------GEAAKAGPLRTPSYTVVDLYGYYKPNKN 669

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 488147709  734 LTLRAGVYNVFNRKYTTWDSLRGLYSYSTtnsvdrdgkgldRYRAPSRNYAVSLEWKF 791
Cdd:TIGR01786 670 LTLRFGVYNLLDRKYTTWESARQAGPLAT------------GYTAPGRNYKASVEYKF 715
 
Name Accession Description Interval E-value
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 29-791 0e+00

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 644.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   29 TETTPVKAEIKAVRvkGQRNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGR-HQKGFAVRGVEGNRVGVSIDG 107
Cdd:TIGR01786   3 ITVTATRTADPQRR--DLSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVVEGGRgGSQGINIRGLDKNRVAVLVDG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  108 VNLPDSEENSLYARYGnfnssRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDLLLDDRQFGVMMKNGYST 187
Cdd:TIGR01786  81 IRQNTSYGGQGSTFYA-----INSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLGYSS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  188 RNREWTNTLGFGVSNDRVDAALLYSQRRGHETESAGNRGYavegegsganIRGSARGIPDSSKHKYHSFLGKIAYQINDN 267
Cdd:TIGR01786 156 ANNRFTQSVAAAGRNDDVDALVQATYRRGHELKNGNKANI----------GNESKRSKPNPSDYKSQSFLAKLGWQLNDA 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  268 HRIGASLNGQQGHNYTVEESY----------NLTASSWREADDVNRRRNANLFYEWMPDSNWLSSLKADFDYQKTKVAAV 337
Cdd:TIGR01786 226 HRLGLSLEYTQTDYDEPEMTNtsyltkplgaPLLSSTVVLGDSKTRDRRTGLDYELNPDNSWLDTVKLALDKQYIQLYNY 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  338 NNKGSFPmDYSTWTRNYNQKDLDEIYNRSMDTRFKRfTLRLDSHPLQLGGGRHRLSFKTFVSRRDFENLNRDDYYFSGrv 417
Cdd:TIGR01786 306 LNATSAS-DYPGVDKNGRYKDKYDYYTLGFDTNNKI-EFSVHSLSLTYGLDRFKDKVSTGDSRRNLPTAAYNLYGYEG-- 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  418 vrttssIQHPVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQElnaecHACDKTPPAANTYKGWSGFVGLAAQLNQ 497
Cdd:TIGR01786 382 ------ENRPVKGSNFGLFLQDNIKLGDWLSLSAGLRYDHYKTDPKA-----DESKDYGAISKTYSRWSPSLGLTYKPTP 450

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  498 AWHVGYDITSGYRVPNASEVYFTYNHGSG---NWLPNPNLKAERSTTHTLSLQGRSEKGMLDANLYQSNYRNFLSEEQKL 574
Cdd:TIGR01786 451 WLTLYYSYSQGFRAPSFDELYGTGAHPGGgpyTFLPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGIGV 530

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  575 TTSGtpgctEENAYYGICSDPYkekldwqmKNIDKARIRGIELTGRLNVDKVASFvPEGWKLFGSLGYAKSKLSGDNSLL 654
Cdd:TIGR01786 531 TAKG-----NMAQVGSNTITNY--------VNIDNARIRGIELSGRYDLGSFFSG-PDGWTTTLKYGYTKGKDSDTNPWL 596

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  655 -STQPLKVIAGIDYESPSEKWGVFSRLTYLGAKKAKDAQYTVYENkgwgtplQKKVKDYPWLNKSAYVFDMYGFYKPAKN 733
Cdd:TIGR01786 597 nAITPLKVVLGLGYDHPDEKWGVGLTLTFSGAKDAVDAYATYYEN-------GEAAKAGPLRTPSYTVVDLYGYYKPNKN 669

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 488147709  734 LTLRAGVYNVFNRKYTTWDSLRGLYSYSTtnsvdrdgkgldRYRAPSRNYAVSLEWKF 791
Cdd:TIGR01786 670 LTLRFGVYNLLDRKYTTWESARQAGPLAT------------GYTAPGRNYKASVEYKF 715
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 61-791 5.72e-93

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 304.37  E-value: 5.72e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  61 IKQEMIRDN-----KDLVRYSTDVGLSDSGR-HQKGFAVRGVEGNRVGVSIDGVNLPDSEenslYARYGNFNSsrlsIDP 134
Cdd:cd01347    5 ITAEDIEKQpatslADLLRRIPGVSVTRGGGgGGSTISIRGFGPDRTLVLVDGLPLASSN----YGRGVDLNT----IPP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 135 ELVRNIEIVKGADSFNTGSGALGGGVNYQTLQgrdlllDDRQFGVMMKNGYSTRNREWTNTLGFGVSndrvdaallysqR 214
Cdd:cd01347   77 ELIERVEVLKGPSSALYGSGAIGGVVNIITKR------PTDEFGGSVTAGYGSDNSGSSGGGGFDVS------------G 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 215 RGHETESAGNRGYAVEGEGSGANIRGsarGIPDSSKHKYHSFLGKIAYQINDNHRIGASLNGQQGHNYTVEESYNLTAS- 293
Cdd:cd01347  139 ALADDGAFGARLYGAYRDGDGTIDGD---GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTg 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 294 -----------SWREADDVNRRRNANLFYEWMPDSNWLS-SLKADFDYQKTKVAAVNNKgsfpmdYSTWTRNYNQKDLDE 361
Cdd:cd01347  216 sslgggpssntNGDRDWDYRDRYRKRASLGLEHDLNDTGwTLRANLSYSYTDNDGDPLI------LNGGNNAAGGDLGRS 289

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 362 IYNRSMDTRFKRFTLRLDShPLQLGGGRHRLSFktfvsrrdfeNLNRDDYYFsgrvvrttssiqhpvKTTNYGFSLSDQI 441
Cdd:cd01347  290 GYSSERDTTQLGFDAGLNA-PFGTGPVAHTLTL----------GVEYRREEL---------------DEKQTALYAQDTI 343

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 442 QWNDVFSSRAGIRYDHTKMTPQELNAechacdKTPPAANTYKGWSGFVGLAAQLNQAWHVGYDITSGYRVPNASEVYFTY 521
Cdd:cd01347  344 ELTDDLTLTLGLRYDHYDQDSKDTIA------GGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGG 417

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 522 NHGSGNWLPNPNLKAERSTTHTLSLQGRSEKG-MLDANLYQSNYRNFLSEEqklttsgtpgcteenayygicSDPYKEKL 600
Cdd:cd01347  418 SHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGlTLSAALFRIDIKNEIVST---------------------PTNTGLGL 476

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 601 DWQMKNIDKARIRGIELTGRLNvdkvasfVPEGWKLFGSLGYAKSK------LSGDNSLLSTQPLKVIAGIDYESPSEKW 674
Cdd:cd01347  477 VTVYVNGGKARIRGVELEASYD-------LTDGLGLTGSYTYTDTEvkrtdgATTGNRLPGIPKHTANLGLDYELPDEGL 549

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 675 GVFSRLTYLGAKKAKDAqytvyenkgwGTPLQKKVKDYpwlnksaYVFDMYGFYKPAKNLTLRAGVYNVFNRKYTTWDSL 754
Cdd:cd01347  550 TAGGGVRYRGKQYADTA----------NGNNTVKVPGY-------TLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSV 612

                        730       740       750
                 ....*....|....*....|....*....|....*..
gi 488147709 755 RGLYSYsttnsvdrdgkgldRYRAPSRNYAVSLEWKF 791
Cdd:cd01347  613 RGSGLY--------------GYYGPGRTYYLSVSYKF 635
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
38-763 4.50e-77

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 262.07  E-value: 4.50e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  38 IKAVRVKGQR------NAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGRHQKGFAVRGVEG--NRVGVSIDGVN 109
Cdd:COG1629    1 LEEVVVTATRtdeslqDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGggNRVLVLVDGVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 110 LPDSeenslyaryGNFNSSRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDlllddrQFGVMMKNGYSTRN 189
Cdd:COG1629   81 LNDP---------SGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGSYG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 190 ReWTNTLGFGVSNDRVDAALLYSQRRGHetesagnrgyavegegsganirgsarGIPDSSKHKYHSFLGKIAYQINDNHR 269
Cdd:COG1629  146 T-YRASLSLSGGNGKLAYRLSASYRDSD--------------------------GYRDNSDSDRYNLRAKLGYQLGDDTR 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 270 IGASLNG----QQGHNYTVEESYNLTAS------SWREADDVNRRRNANLFYEWMPDSNWLSsLKADFDYQKTKVaavnn 339
Cdd:COG1629  199 LTLSASYsdsdQDSPGYLTLAALRPRGAmddgtnPYSNDTDDNTRDRYSLSLEYEHLGDGLK-LSASAYYRYDDT----- 272

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 340 kgsfpmdYSTWTRNYNQKDLDEIYNRSMDTRFKRFTLRLDSHPLqlGGGRHRLSFKTFVSRRDFENLNRDDYYFSGRVVR 419
Cdd:COG1629  273 -------DLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLG--FGGKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPT 343

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 420 TTSSIQHPVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQELNAEchacDKTPPAANTYKGWSGFVGLAAQLNQAW 499
Cdd:COG1629  344 LTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVDDTVTG----TDSASGSRSYSAFSPSLGLTYQLSPNL 419

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 500 HVGYDITSGYRVPNASEVYFTYNhgSGNWLPNPNLKAERSTTHTLSLQGR--SEKGMLDANLYQSNYRNFLSEEQKLTTS 577
Cdd:COG1629  420 SLYASYSRGFRAPTFGELYANGT--DPYSVGNPDLKPETSTNYELGLRYRllDGRLSLSLALFYSDVDNEILSVPLPNDS 497

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 578 GTPgcteenayygicsdpykekldWQMKNIDKARIRGIELTGRLNVDkvasfvpEGWKLFGSLGYAKSKLSGD------- 650
Cdd:COG1629  498 GFS---------------------TYYTNAGKARSYGVELELSYQLT-------PGLSLNASYSYTDAKFDDDtdgsadl 549

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 651 --NSLLSTQPLKVIAGIDYEsPSEKWGVFSRLTYLGAKKAKDAqytvyenkgwgtplqkkvkDYPWLNKSAYVFDMYGFY 728
Cdd:COG1629  550 dgNRLPGVPPLTANLGLTYE-FPGGWSLGLGVRYVGDRYLDDA-------------------NTQGAPGGYTLVDLGAGY 609

                        730       740       750
                 ....*....|....*....|....*....|....*
gi 488147709 729 KPAKNLTLRAGVYNVFNRKYTTWDSLRGLYSYSTT 763
Cdd:COG1629  610 RFGDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 265-790 5.62e-38

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 148.38  E-value: 5.62e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  265 NDNHRIGASLNGQQGHNYTVEESYNLTASSWREADDVNRRRNANLFYEWMPDSN--WLSSLKADFDYQKTKVAAVNNKGS 342
Cdd:pfam00593  21 YSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGlsWLSTLRLGLRYSSLDGDYTSNSSG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  343 FPMdystwTRNYNQKDLDEIYNRSMDTRFKRFTLRLDShplqLGGGRHRLSFKTFVSRRDFENLNRDDYYFSGRVVRTTs 422
Cdd:pfam00593 101 LSG-----AGDYLSDDRLYGLYGLDGDLELSLDLSHDL----LLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSYSDT- 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  423 siqhpvKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQELNAechacdKTPPAANTYKGWSGFVGLAAQLNQAWHVG 502
Cdd:pfam00593 171 ------TTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNG------GGDNFSRSYSAFSPRLGLVYKPTDNLSLY 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  503 YDITSGYRVPNASEVYFTYNHGSGNWL--PNPNLKAERSTTHTLSLQGRSEKGMLDANLYQSNYRNFLSEEQKLTTSGTP 580
Cdd:pfam00593 239 ASYSRGFRAPSLGELYGSGSGGGGGAVagGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPGLGGT 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  581 gcteenayygicsdpykeklDWQMKNIDKARIRGIELTGRLNVdkvasfvpegWKLFGSLG--------YAKSKLSGDNS 652
Cdd:pfam00593 319 --------------------VYTYTNVGKARIRGVELELSGRL----------WGLGLSGGgytytdadDDADADDTGNP 368

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  653 LLSTQPLKVIAGIDYESPSEKWGVFSRLTYLGAKKAKDAQYT-VYENKGWGtplqkkvkdypwlnksayVFDMYGFYKPA 731
Cdd:pfam00593 369 LPNVPRHTANLGLTYDFPLGGWGARLGARYVGSGERRYGDAAnTFKTPGYT------------------LVDLSAGYRLN 430

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 488147709  732 KNLTLRAGVYNVFNRKYTTWDSLRGLYSYsttnsvdrdgkgldRYRAPSRNYAVSLEWK 790
Cdd:pfam00593 431 KNLTLRLGVNNLFDKYYKRYYSSGGGNLG--------------GYPGPGRTFYLGLSYK 475
PRK13483 PRK13483
ligand-gated channel protein;
4-791 6.34e-17

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 85.21  E-value: 6.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   4 LQMLPIAALVGSIFGNPVLAADE--AATETTPVKAEIKAvrvKGQRNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGL 81
Cdd:PRK13483   6 AQVISALCLLPAVFVTHALAQAApdKTMETVVVTASGYE---QQIRDAPASISVITREDLENRFYRDLTDALLDVPGVVV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  82 SDSGRHQKgFAVRGVEGNRVGVSIDGvnlpdSEENSlyaRYGNFNSSRLSID----PEL--VRNIEIVKGADSFNTGSGA 155
Cdd:PRK13483  83 TGGGDRTD-ISLRGMGSQYTLILVDG-----KRQSS---RETRPNSDGPGVEqawtPPLaaIERIEVIRGPMSSLYGSDA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 156 LGGGVNYQTLQGRDLLLDDRQFGVMMKNGYSTRNREWTNtlgFGVSNDRVDAAL---LYSQ--RRGHETESAGNRGYAVE 230
Cdd:PRK13483 154 IGGVINIITRKVPNEWQGEVRLDTTLQENSDSGNVYQAN---FFVNGPLIKDLLglqLYGQytQREEDDIEGGYRDKDAR 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 231 gegsganirgsargipdsskhkyhSFLGKIAYQINDNHRIGASLNGQQGHnytVEESYNLTASSWREADDVNRRRNANLf 310
Cdd:PRK13483 231 ------------------------SLTAKLALTPNEDHDIMLEVGTSNQE---RDSTVGKTVAPLAPGESCGRRGCPES- 282

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 311 yewmpdsnwlsslkADFDYQKTKVAaVNNKGSFPMDYStwtRNYNQKDldEIYNRSMDTRFKRFTLRLD-SHPLqlgGGR 389
Cdd:PRK13483 283 --------------STTEYERSTVS-LSHTGRWDFGTS---DTYIQHE--EFDNKSREMKIKNTDFQSSlVAPL---GQE 339

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 390 HRLSFKTfvsrrDFENLNRDDyyfsgrvvRTTSSIQHPVKTTNYGFSLSDQIQWN--DVFSSRAGIRYDHTKmtpqelNA 467
Cdd:PRK13483 340 HTLTFGA-----AYNHQDLTD--------ETSNQISDLTDISRTQWAVFSEDEWRiaDDFALTGGLRLDHDE------NF 400

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 468 ECHAcdktppAANTYKGWsgfvglaaQLNQAWHVGYDITSGYRVPNASEVYFTYNHGS--GNWLPNPNLKAERSTTHTLS 545
Cdd:PRK13483 401 GGHV------SPRVYGVW--------NLAPSWTVKGGVSTGFRAPSLRQTTPDWGQVSrgGNIYGNPDLKPETSLNKELG 466

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 546 LQGRSEKGmLDANLyQSNYRNFlseEQKLTTSGTPG--CTEENAYYGicSDPYKEKldwqmkNIDKARIRGIELTGRLNV 623
Cdd:PRK13483 467 LYYDLGSG-LTASL-TVFYNEF---KDKITRVACPAtqCTDGPNQFG--ADPTTYV------NIDEAVTQGVEASLSYPI 533

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 624 DkvasfvpEGWKLFGSLGYAKS-KLSGDnslLSTQPLK------VIAGIDYEsPSEKWGVFSRLTYLGakkaKDAQYTvy 696
Cdd:PRK13483 534 T-------STLSLSGNYTYTDSeQKSGA---YKGSPLNqlpkhlFQASLNWE-PTDRLNSWARVNYRG----EESQPT-- 596

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 697 enkgwGTPLQKKVKdypwlnKSAYVF-DMYGFYKPAKNLTLRAGVYNVFNRKYTTWDslrglYSYSttnsvdRDGkgldr 775
Cdd:PRK13483 597 -----TGPSSSSFI------APSYTFlDLGANYQLTDNLKLSAGIYNLFDKEINYEE-----YGYV------EDG----- 649

                        810
                 ....*....|....*.
gi 488147709 776 yrapsRNYAVSLEWKF 791
Cdd:PRK13483 650 -----RRYWLGMTYSF 660
 
Name Accession Description Interval E-value
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 29-791 0e+00

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 644.08  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   29 TETTPVKAEIKAVRvkGQRNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGR-HQKGFAVRGVEGNRVGVSIDG 107
Cdd:TIGR01786   3 ITVTATRTADPQRR--DLSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVVEGGRgGSQGINIRGLDKNRVAVLVDG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  108 VNLPDSEENSLYARYGnfnssRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDLLLDDRQFGVMMKNGYST 187
Cdd:TIGR01786  81 IRQNTSYGGQGSTFYA-----INSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLGYSS 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  188 RNREWTNTLGFGVSNDRVDAALLYSQRRGHETESAGNRGYavegegsganIRGSARGIPDSSKHKYHSFLGKIAYQINDN 267
Cdd:TIGR01786 156 ANNRFTQSVAAAGRNDDVDALVQATYRRGHELKNGNKANI----------GNESKRSKPNPSDYKSQSFLAKLGWQLNDA 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  268 HRIGASLNGQQGHNYTVEESY----------NLTASSWREADDVNRRRNANLFYEWMPDSNWLSSLKADFDYQKTKVAAV 337
Cdd:TIGR01786 226 HRLGLSLEYTQTDYDEPEMTNtsyltkplgaPLLSSTVVLGDSKTRDRRTGLDYELNPDNSWLDTVKLALDKQYIQLYNY 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  338 NNKGSFPmDYSTWTRNYNQKDLDEIYNRSMDTRFKRfTLRLDSHPLQLGGGRHRLSFKTFVSRRDFENLNRDDYYFSGrv 417
Cdd:TIGR01786 306 LNATSAS-DYPGVDKNGRYKDKYDYYTLGFDTNNKI-EFSVHSLSLTYGLDRFKDKVSTGDSRRNLPTAAYNLYGYEG-- 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  418 vrttssIQHPVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQElnaecHACDKTPPAANTYKGWSGFVGLAAQLNQ 497
Cdd:TIGR01786 382 ------ENRPVKGSNFGLFLQDNIKLGDWLSLSAGLRYDHYKTDPKA-----DESKDYGAISKTYSRWSPSLGLTYKPTP 450

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  498 AWHVGYDITSGYRVPNASEVYFTYNHGSG---NWLPNPNLKAERSTTHTLSLQGRSEKGMLDANLYQSNYRNFLSEEQKL 574
Cdd:TIGR01786 451 WLTLYYSYSQGFRAPSFDELYGTGAHPGGgpyTFLPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGIGV 530

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  575 TTSGtpgctEENAYYGICSDPYkekldwqmKNIDKARIRGIELTGRLNVDKVASFvPEGWKLFGSLGYAKSKLSGDNSLL 654
Cdd:TIGR01786 531 TAKG-----NMAQVGSNTITNY--------VNIDNARIRGIELSGRYDLGSFFSG-PDGWTTTLKYGYTKGKDSDTNPWL 596

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  655 -STQPLKVIAGIDYESPSEKWGVFSRLTYLGAKKAKDAQYTVYENkgwgtplQKKVKDYPWLNKSAYVFDMYGFYKPAKN 733
Cdd:TIGR01786 597 nAITPLKVVLGLGYDHPDEKWGVGLTLTFSGAKDAVDAYATYYEN-------GEAAKAGPLRTPSYTVVDLYGYYKPNKN 669

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 488147709  734 LTLRAGVYNVFNRKYTTWDSLRGLYSYSTtnsvdrdgkgldRYRAPSRNYAVSLEWKF 791
Cdd:TIGR01786 670 LTLRFGVYNLLDRKYTTWESARQAGPLAT------------GYTAPGRNYKASVEYKF 715
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 61-791 5.72e-93

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 304.37  E-value: 5.72e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  61 IKQEMIRDN-----KDLVRYSTDVGLSDSGR-HQKGFAVRGVEGNRVGVSIDGVNLPDSEenslYARYGNFNSsrlsIDP 134
Cdd:cd01347    5 ITAEDIEKQpatslADLLRRIPGVSVTRGGGgGGSTISIRGFGPDRTLVLVDGLPLASSN----YGRGVDLNT----IPP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 135 ELVRNIEIVKGADSFNTGSGALGGGVNYQTLQgrdlllDDRQFGVMMKNGYSTRNREWTNTLGFGVSndrvdaallysqR 214
Cdd:cd01347   77 ELIERVEVLKGPSSALYGSGAIGGVVNIITKR------PTDEFGGSVTAGYGSDNSGSSGGGGFDVS------------G 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 215 RGHETESAGNRGYAVEGEGSGANIRGsarGIPDSSKHKYHSFLGKIAYQINDNHRIGASLNGQQGHNYTVEESYNLTAS- 293
Cdd:cd01347  139 ALADDGAFGARLYGAYRDGDGTIDGD---GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTg 215

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 294 -----------SWREADDVNRRRNANLFYEWMPDSNWLS-SLKADFDYQKTKVAAVNNKgsfpmdYSTWTRNYNQKDLDE 361
Cdd:cd01347  216 sslgggpssntNGDRDWDYRDRYRKRASLGLEHDLNDTGwTLRANLSYSYTDNDGDPLI------LNGGNNAAGGDLGRS 289

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 362 IYNRSMDTRFKRFTLRLDShPLQLGGGRHRLSFktfvsrrdfeNLNRDDYYFsgrvvrttssiqhpvKTTNYGFSLSDQI 441
Cdd:cd01347  290 GYSSERDTTQLGFDAGLNA-PFGTGPVAHTLTL----------GVEYRREEL---------------DEKQTALYAQDTI 343

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 442 QWNDVFSSRAGIRYDHTKMTPQELNAechacdKTPPAANTYKGWSGFVGLAAQLNQAWHVGYDITSGYRVPNASEVYFTY 521
Cdd:cd01347  344 ELTDDLTLTLGLRYDHYDQDSKDTIA------GGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGG 417

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 522 NHGSGNWLPNPNLKAERSTTHTLSLQGRSEKG-MLDANLYQSNYRNFLSEEqklttsgtpgcteenayygicSDPYKEKL 600
Cdd:cd01347  418 SHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGlTLSAALFRIDIKNEIVST---------------------PTNTGLGL 476

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 601 DWQMKNIDKARIRGIELTGRLNvdkvasfVPEGWKLFGSLGYAKSK------LSGDNSLLSTQPLKVIAGIDYESPSEKW 674
Cdd:cd01347  477 VTVYVNGGKARIRGVELEASYD-------LTDGLGLTGSYTYTDTEvkrtdgATTGNRLPGIPKHTANLGLDYELPDEGL 549

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 675 GVFSRLTYLGAKKAKDAqytvyenkgwGTPLQKKVKDYpwlnksaYVFDMYGFYKPAKNLTLRAGVYNVFNRKYTTWDSL 754
Cdd:cd01347  550 TAGGGVRYRGKQYADTA----------NGNNTVKVPGY-------TLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSV 612

                        730       740       750
                 ....*....|....*....|....*....|....*..
gi 488147709 755 RGLYSYsttnsvdrdgkgldRYRAPSRNYAVSLEWKF 791
Cdd:cd01347  613 RGSGLY--------------GYYGPGRTYYLSVSYKF 635
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
38-763 4.50e-77

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 262.07  E-value: 4.50e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  38 IKAVRVKGQR------NAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGRHQKGFAVRGVEG--NRVGVSIDGVN 109
Cdd:COG1629    1 LEEVVVTATRtdeslqDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGggNRVLVLVDGVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 110 LPDSeenslyaryGNFNSSRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDlllddrQFGVMMKNGYSTRN 189
Cdd:COG1629   81 LNDP---------SGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASYGSYG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 190 ReWTNTLGFGVSNDRVDAALLYSQRRGHetesagnrgyavegegsganirgsarGIPDSSKHKYHSFLGKIAYQINDNHR 269
Cdd:COG1629  146 T-YRASLSLSGGNGKLAYRLSASYRDSD--------------------------GYRDNSDSDRYNLRAKLGYQLGDDTR 198

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 270 IGASLNG----QQGHNYTVEESYNLTAS------SWREADDVNRRRNANLFYEWMPDSNWLSsLKADFDYQKTKVaavnn 339
Cdd:COG1629  199 LTLSASYsdsdQDSPGYLTLAALRPRGAmddgtnPYSNDTDDNTRDRYSLSLEYEHLGDGLK-LSASAYYRYDDT----- 272

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 340 kgsfpmdYSTWTRNYNQKDLDEIYNRSMDTRFKRFTLRLDSHPLqlGGGRHRLSFKTFVSRRDFENLNRDDYYFSGRVVR 419
Cdd:COG1629  273 -------DLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLG--FGGKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPT 343

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 420 TTSSIQHPVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQELNAEchacDKTPPAANTYKGWSGFVGLAAQLNQAW 499
Cdd:COG1629  344 LTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVDDTVTG----TDSASGSRSYSAFSPSLGLTYQLSPNL 419

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 500 HVGYDITSGYRVPNASEVYFTYNhgSGNWLPNPNLKAERSTTHTLSLQGR--SEKGMLDANLYQSNYRNFLSEEQKLTTS 577
Cdd:COG1629  420 SLYASYSRGFRAPTFGELYANGT--DPYSVGNPDLKPETSTNYELGLRYRllDGRLSLSLALFYSDVDNEILSVPLPNDS 497

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 578 GTPgcteenayygicsdpykekldWQMKNIDKARIRGIELTGRLNVDkvasfvpEGWKLFGSLGYAKSKLSGD------- 650
Cdd:COG1629  498 GFS---------------------TYYTNAGKARSYGVELELSYQLT-------PGLSLNASYSYTDAKFDDDtdgsadl 549

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 651 --NSLLSTQPLKVIAGIDYEsPSEKWGVFSRLTYLGAKKAKDAqytvyenkgwgtplqkkvkDYPWLNKSAYVFDMYGFY 728
Cdd:COG1629  550 dgNRLPGVPPLTANLGLTYE-FPGGWSLGLGVRYVGDRYLDDA-------------------NTQGAPGGYTLVDLGAGY 609

                        730       740       750
                 ....*....|....*....|....*....|....*
gi 488147709 729 KPAKNLTLRAGVYNVFNRKYTTWDSLRGLYSYSTT 763
Cdd:COG1629  610 RFGDNLTLSLGVDNLFDKKYATSLSVRASNVRGFL 644
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 49-791 4.63e-67

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 234.98  E-value: 4.63e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   49 APAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGRHQ-KGFAVRGVEGNRVGVSIDGVNLPDSeenslyarYGNFNS 127
Cdd:TIGR01785  18 APASVSVISGEQIESKQANNLADALNTVPGVDVTGGGRPPgQSINIRGLQDNRVLVVVDGARQNYQ--------RGGAHN 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  128 SRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDLLLDDRQFGVMMKNGYSTRNREW-TNTLGFGVSNDRVD 206
Cdd:TIGR01785  90 GSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLAKLSYGSNNNSFgGSVAVAGRLDDNLD 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  207 AALLYSQRRGHET-----ESAGNRGYAVEGegsganirgsargipdsskhkyhsFLGKIAYQINDNHRIGASL---NGQQ 278
Cdd:TIGR01785 170 ALVAATYRDGGNYrngnkEEATNSAYVQKN------------------------LLAKLGWQLDDAQRLEFSYfttEGSL 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  279 GHNYTVEESYNLT-ASSWREADDVNRRRNANLFYEWMPDSNWLSSLKADFDYQKTkvaavnnkgsfPMDYSTWTRNYNQK 357
Cdd:TIGR01785 226 DEAQNSGPGTEYVlGSSSTLLASSTRDRSATLTYNWTPEDNPWLDATASLYYNRT-----------ENDNDRSARGVGRE 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  358 DldeiynrsmDTRFKRFTLRLDSHPLQLGGGRHRLSFKTfvsrrDFENLNRDDYYFSGRVVRTTSSIQHPVKTTNYGFSL 437
Cdd:TIGR01785 295 E---------GYQYTTYGATLQNTSRFDVASWSTLTYGV-----DWMKDKRRTESFDPNSVTTIVPNPPSAKEYFFGLFL 360

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  438 SDQIQ-WNDVFSSRAGIRYDHTKMTPQelnaechACDKTPPAANTYKGWSGFVGLAAQLNQAWHVGYDITSGYRVPNASE 516
Cdd:TIGR01785 361 QDNIPlLDDRLTLSAGLRYDHYKLSPK-------TTADTEAVDRSYSRWSPSLGLSYKPVDWLTLYASYSQGFRAPSIDE 433

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  517 VYFTYNH----GSGNWLPNPNLKAERSTTHTLSLQGRSEKGMLD-------ANLYQSNYRNFLSEEQKLTTSGTPGCTEE 585
Cdd:TIGR01785 434 LYGTGDHpgtpGGYTFAPNPNLKPETSKTWELGANLSFDNLLLDndqlqfkVAYFYNDVKDFIDLTIGVTDNVTAGMNNI 513

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  586 NAYygicsdpykekldwqmKNIDKARIRGIELTGRLNVDKvasfvpegWKLFGSLGYAKSKLSGDNSLLST-QPLKVIAG 664
Cdd:TIGR01785 514 TQY----------------VNIDGARIRGIEASASYDAGL--------WATGLSYGYTIGKDQNTNQWLSNiPPLKLVVT 569

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  665 IDYESPSEKWGVFSRLTYlgaKKAKDAQYTVYENKGWGTPlqkkvkDYPwlnkSAYVFDMYGFYKPA--KNLTLRAGVYN 742
Cdd:TIGR01785 570 VGYRFPDRRLDLGAKAAY---YERQSESPTTEDVAANGLL------TTP----GYTVVDLYATYQPNavKGLTVRFGVNN 636

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*....
gi 488147709  743 VFNRKYTTWDSLRGlysysttnsvdrdgkgldryRAPSRNYAVSLEWKF 791
Cdd:TIGR01785 637 LTDRKYTPAQSVPG--------------------AGPGRNFKGSVKYQF 665
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 21-737 3.73e-50

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 186.22  E-value: 3.73e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  21 VLAADEAATETTPVKAEIKAVRVKGQR------NAPAAVERVNLNRIKQEMIRDNKDLVRY--STDVGLSDSGRHQKGFA 92
Cdd:COG4771   10 LALAAQAADALAEDATELEEVVVTATRteqslsDAPASVSVITAEEIEKLGATDLADALRLlpGVSVTRSGGRGGSSGIS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  93 VRGVEGNRVGVSIDGVNLPdseeNSLYARYGNFNSsrlsIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDLLL 172
Cdd:COG4771   90 IRGLGGDRVLVLIDGVPVN----NPALGGGGDLSY----IPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 173 DDRQFGvmmknGYSTRNREWTNTLGFGVSNDRVDAALLYSQRRGHETESAGNRGYAvegegsganirgsargipDSSKHK 252
Cdd:COG4771  162 GSVSLG-----YGSNGNGTYSGSLSLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFV------------------GNSGYE 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 253 YHSFLGKIAYQINDNHRIGASLNGQQGHNYTVEESYNLTA---SSWREADDVNRRRNANLFYEWmpdsNWLSSLKADFDY 329
Cdd:COG4771  219 RYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEissDNAGDRDTTTDRGNYSLRYNG----DLGDNLDLSLYY 294

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 330 QKTKvaavnnkgsfpmdystwtRNYNQKDLDEIYNRSMDTRFKRFTLRLD-SHPLqlgGGRHRLSFKTFVSRRDFENlnr 408
Cdd:COG4771  295 SRTD------------------RDSTNGSLGGSTGSFSDSDDTTYGLELDlTYPL---GGNHTLTLGAEYRYDDLDS--- 350

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 409 ddyyfsgrvvrTTSSIQHPVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTpqelnaechacdktppAANTYKGWSGF 488
Cdd:COG4771  351 -----------SSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTF----------------GASNYTAFSPR 403

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 489 VGLAAQLNQAWHVGYDITSGYRVPNASEVYFTYNHGSGNW-LPNPNLKAERSTTHTLSLQGR--SEKGMLDANLYQSNYR 565
Cdd:COG4771  404 LGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRYvLGNPDLKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIK 483

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 566 NFLSEEQKLTTSGTPgcteenayygicsdpykekldWQMKNIDKARIRGIELTGRLNVDKvasfvpeGWKLFGSLGYAKS 645
Cdd:COG4771  484 DLIVLVPVGPGPGDV---------------------LQYENVGKARTYGLELELKYRLGK-------GLTLTASYTYLDS 535

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 646 KL---SGDNSLLSTQPLKVIAGIDYESPseKWGVFSRLTYLGAKKAKDAQYTVYENKgwgtplqkkvkdypwlNKSAYVF 722
Cdd:COG4771  536 KIddgDTGEPLPNVPPHKANLGLDYRLP--KWWLLLLLTRYYGGRYVTPPSGRLEGY----------------TPGYTLL 597

                        730
                 ....*....|....*
gi 488147709 723 DMYGFYKPAKNLTLR 737
Cdd:COG4771  598 DLRASYKLTKNLTLS 612
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 265-790 5.62e-38

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 148.38  E-value: 5.62e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  265 NDNHRIGASLNGQQGHNYTVEESYNLTASSWREADDVNRRRNANLFYEWMPDSN--WLSSLKADFDYQKTKVAAVNNKGS 342
Cdd:pfam00593  21 YSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGlsWLSTLRLGLRYSSLDGDYTSNSSG 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  343 FPMdystwTRNYNQKDLDEIYNRSMDTRFKRFTLRLDShplqLGGGRHRLSFKTFVSRRDFENLNRDDYYFSGRVVRTTs 422
Cdd:pfam00593 101 LSG-----AGDYLSDDRLYGLYGLDGDLELSLDLSHDL----LLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSYSDT- 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  423 siqhpvKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQELNAechacdKTPPAANTYKGWSGFVGLAAQLNQAWHVG 502
Cdd:pfam00593 171 ------TTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNG------GGDNFSRSYSAFSPRLGLVYKPTDNLSLY 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  503 YDITSGYRVPNASEVYFTYNHGSGNWL--PNPNLKAERSTTHTLSLQGRSEKGMLDANLYQSNYRNFLSEEQKLTTSGTP 580
Cdd:pfam00593 239 ASYSRGFRAPSLGELYGSGSGGGGGAVagGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPGLGGT 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  581 gcteenayygicsdpykeklDWQMKNIDKARIRGIELTGRLNVdkvasfvpegWKLFGSLG--------YAKSKLSGDNS 652
Cdd:pfam00593 319 --------------------VYTYTNVGKARIRGVELELSGRL----------WGLGLSGGgytytdadDDADADDTGNP 368

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  653 LLSTQPLKVIAGIDYESPSEKWGVFSRLTYLGAKKAKDAQYT-VYENKGWGtplqkkvkdypwlnksayVFDMYGFYKPA 731
Cdd:pfam00593 369 LPNVPRHTANLGLTYDFPLGGWGARLGARYVGSGERRYGDAAnTFKTPGYT------------------LVDLSAGYRLN 430

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 488147709  732 KNLTLRAGVYNVFNRKYTTWDSLRGLYSYsttnsvdrdgkgldRYRAPSRNYAVSLEWK 790
Cdd:pfam00593 431 KNLTLRLGVNNLFDKYYKRYYSSGGGNLG--------------GYPGPGRTFYLGLSYK 475
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
23-791 5.27e-31

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 129.66  E-value: 5.27e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  23 AADEAATETTPVkaEIKAVRVKGQR--NAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGrhqkGFA------VR 94
Cdd:COG4772   15 AAAEAATTLETV--VVTGSRAAEARlkDVPGSVSVVDREELENQAATSLREVLRRVPGVNVQEED----GFGlrpnigIR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  95 GVEGNRV-GVSI--DGVNLPdseenslYARYGNfNSSRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDll 171
Cdd:COG4772   89 GLGPRRSrGITLleDGIPIA-------PAPYGD-PAAYYFPDLERMERIEVLRGAAALRYGPQTVGGAINFVTRTIPT-- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 172 lddrQFGVMMKNGYSTRNrEWTNTLGFGVSNDRVDAALLYSQRRGHetesaGNRgyavegegsganirgsargipDSSKH 251
Cdd:COG4772  159 ----AFGGELRVTGGSFG-YRRTHASVGGTVGNFGYLVEYSRKRGD-----GFR---------------------DNSGF 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 252 KYHSFLGKIAYQINDNHRIGASLNgqqgHNYTVEESY-NLTASSW--------READDVNRRRN-ANLFYEWMPDSNWLS 321
Cdd:COG4772  208 DINDFNAKLGYRLSDRQELTLKFQ----YYDEDANTPgGLTDAQFdadprqsyRPADQFDTRRTqLSLRYEHQLSDNTTL 283

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 322 SLKA---DFD-YQKTKVAAvNNKGSFPMDYSTWTRNYnqkdldeiYNRSMDTRFkrftlrldSHPLQLGGGRHRLSFKTF 397
Cdd:COG4772  284 TTTAyynDFSrNWYIRQNT-ADPNTPGLGLRGNPRGY--------RSYGIEPRL--------THRFELGGVPHTLEVGLR 346

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 398 VSRRDFENLNRDDYYFSGRVVRTTSSIQHpVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQelNAECHACDKTPP 477
Cdd:COG4772  347 YHREEEDRKQYVNTYGQGRSGAGLRRDRR-FSADALAAYAQNRFELTGRLTLTPGLRYEHIRRDRT--DRYSTRTGGDDS 423

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 478 AANTYKGWSGFVGLAAQLNQAWHVGYDITSGYRVPNASEvyFTYNHGSgnwlpNPNLKAERSTTHTLSLQGRSEKGM-LD 556
Cdd:COG4772  424 GSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGD--LAYGNGG-----NPDLKPEKSWNYELGTRGRIGNGLsAE 496

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 557 ANLYQSNYRNFLseeqkLTTSGTPGCTEENayygicsdpykekldwqmKNIDKARIRGIELTGRLNVDKVASFvpeGWKL 636
Cdd:COG4772  497 VALFYIDYDNEL-----GSCSAAGGDRSTF------------------TNAGETRHQGLELALDYDLLKGGGL---GLPL 550

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 637 FGSLGYAKSKL-------SGDNSLLSTQPLKVIAGIDYEspSEKWGVFSRLTYLGakkakdAQYTVYENkGWGTPLQKKV 709
Cdd:COG4772  551 FAAYTYTDAEFtsdfgpvFAGNRLPYVPRHQLTAGLGYE--HGGWTANLNGRYVS------EQFTDAAN-TVADGSFGKI 621

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 710 KDYpwlnksaYVFDMYGFYKPAKNLTLRAGVYNVFNRKYttwdslrglysYSTTNSVDRDGkgldRYRAPSRNYAVSLEW 789
Cdd:COG4772  622 PSY-------TVLDLSASYDFGKNLSLFAGVNNLFDKRY-----------IASRAPNYAAG----IRPGPPRTVYAGLRL 679


                 ..
gi 488147709 790 KF 791
Cdd:COG4772  680 KF 681
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
47-791 1.12e-26

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 116.13  E-value: 1.12e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  47 RNAPAAVervnlNRIKQEMIRDN-----KDLVRYSTDVGLSDS-GRHQKGFAVRGVEgNRVGVSIDGVNLPdseenslya 120
Cdd:COG4774    7 LDTPQSV-----TVVTRELIEDQgatslADALRNVPGVTFGAGeGGNGDSFSIRGFS-ASGDIYVDGLRDP--------- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 121 rygnfnsSRLSIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDlllddrqfgvmmkngystrnrEWTNTLGFGV 200
Cdd:COG4774   72 -------GQYRRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTD---------------------EPFTEVTLTY 123

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 201 -SNDRVDAALLYSQRRGHETesagnrGYAVEGEGSGANirgSARgipDSSKHKYHSFLGKIAYQINDNHRIGASLNGQQG 279
Cdd:COG4774  124 gSDGQRRATLDVNGPLGDDL------AYRLNGMYRDSD---SYR---DGVDNDRWGIAPSLTWRLGDRTRLTLDYEYQDD 191

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 280 HNYTveeSYNLTASSWREADDVNRRRN--------------ANLFYEWMPDSNWlsSLKADFDYQKTKVAAVNNKGSFPM 345
Cdd:COG4774  192 DRTP---DYGVPAVANGRPVDVDRSTFygqpddysdsetdsATLRLEHDFNDNW--TLRNALRYSDYDRDYRNTYPTGGN 266

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 346 DYSTWTRNYNQKDldeiynrsmdTRFKRFTLRLD-SHPLQLGGGRHRLSFKTFVSRRDFENlnrddYYFSGRVVRTTSSI 424
Cdd:COG4774  267 ATGTVTRSAYRRD----------QDNDTLSNQTDlTGKFDTGGVKHTLLAGVEYSREDSDN-----ARYSGGGTAPTVNL 331

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 425 QHPV-----------------KTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQELNAechacdKTPPAANTYKGWSG 487
Cdd:COG4774  332 YNPVygapvtgptlggadndsRTDTTGLYLQDTISLTDRWSLLAGLRYDRFDTDYTDRTT------GATTSSYDDSAFSP 405

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 488 FVGLAAQLNQAWHV--GYdITSgyRVPNASEVYFTYNhgsgnwlpNPNLKAERSTTHTLSL--QGRSEKGMLDANLYQSN 563
Cdd:COG4774  406 RAGLVYKPTPNLSLyaSY-STS--FNPGGGAPSLSNA--------GQALDPEKSRQYEVGVkwDLLDGRLSLTAALFRIE 474

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 564 YRNFLSeeqklTTSGTPGCTEenayygicsdpykekldwqmkNIDKARIRGIEL--TGRLNvdkvasfvpEGWKLFGSLG 641
Cdd:COG4774  475 KTNVRT-----TDPANPGVYV---------------------QTGEQRSRGVELeaTGELT---------PGWSVLAGYT 519

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 642 YAKSKLSGDNSLLST-QPLKVIA------GIDYESPSEKWGVFSRLTYLGAKKAkDAQYTVyenkgwgtplqkKVKDYpw 714
Cdd:COG4774  520 YLDAEITKSANAANVgNRLPNVPrhsaslWTTYDLPLPGLTLGGGVRYVGSRYA-DAANTV------------KLPSY-- 584

                        730       740       750       760       770       780       790
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488147709 715 lnksaYVFDMYGFYKPAKNLTLRAGVYNVFNRKYttWDSLRGLYSYsttnsvdrdgkgldrYRAPSRNYAVSLEWKF 791
Cdd:COG4774  585 -----TRFDAGASYRLNKNLTLRLNVNNLTDKRY--YASAYGSGYV---------------TPGAPRTVLLSASYRF 639
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 8-791 1.90e-23

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 106.13  E-value: 1.90e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   8 PIAALVGSIFGNPVLAADEAATETTPVKA-EIKAVRVKGQRNA----------------------PAAVERVNLNRIKQE 64
Cdd:COG4773    1 AAALLAGSGLAAAAAGALAQAAAAAAAEAtTLPEVTVTGTAEGtggytakssstatkldtplretPQSVSVVTRQLIEDQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  65 MIRDNKDLVRYSTDV-GLSDSGRHQKGFAVRGVEGNrvGVSIDGVNLpdseenslyarygnFNSSRLSIDPELVRNIEIV 143
Cdd:COG4773   81 GATTLDDALRNVPGVtVSSYDGGGRDSFSIRGFSID--NYLRDGLPL--------------GGFGGGQPDTANLERVEVL 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 144 KGADSFNTGSGALGGGVNYQTLQGRDlllddrqfgvmmkngystrnrEWTNTLGFGVSNdrvdaallYSQRRGH------ 217
Cdd:COG4773  145 KGPAGLLYGAGSPGGLVNLVTKRPTA---------------------EPQGEVSLSAGS--------WDTYRATadvggp 195

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 218 --ETESAGNRGYAVEGEGsganirGSARgipDSSKHKYHSFLGKIAYQINDNHRIGASLNGQQ-------------GHNY 282
Cdd:COG4773  196 lnEDGTLRYRLNAAYEDG------DSFR---DGVDNRRTLIAPSLDWDLTDDTTLTLGAEYQDddstgdrgflpldGTLL 266

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 283 TVEESYNLTasswrEADDVNRRRNANLFY--EWMPDSNWlsSLKADFDYQKTKVAavnnkgsfpmDYSTWTRNYNQKDLD 360
Cdd:COG4773  267 DLPRSTNLG-----EPWDYYDTETTTLFAelEHRFNDDW--SLRANARYSDSDRD----------GRSAYAYGAPDAATG 329

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 361 EI--YNRSMDTRFKRFTLRLD-SHPLQLGGGRHRLSFKTFVSRRDFENLNRDDYYFS------GRVVR-TTSSIQHPVKT 430
Cdd:COG4773  330 TLtrYASARDGDSRSDSLDANlNGKFETGGLEHTLLVGADYSRYDSDSDSATAGTINiynpvyGNLPEpDFDASDTDTTT 409

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 431 TNYGFSLSDQIQWNDVFSSRAGIRYDHTKMTPQELNAechacdkTPPAANTYKGWSGFVGLAaqlnqawhvgYDITsgyr 510
Cdd:COG4773  410 RQTGLYAQDQISLTDRLSLLLGGRYDWYETDSTNRLG-------GSTTSYDDSAFTPRAGLV----------YDLT---- 468

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 511 vPNASeVYFTY----NHGSGNWLPNPNLKAERSTTHTLSLQGRSEKGMLDANL--YQSNYRNFLseeqkLTTSGTPGCTE 584
Cdd:COG4773  469 -PGLS-LYASYsesfEPQSGADNNGNPLDPETGKQYEAGVKGELFDGRLNATLavFDITQKNVA-----TTDPDNPNFYV 541

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 585 enayygicsdpykekldwqmkNIDKARIRGIELTGRLNvdkvasfVPEGWKLFGSLGYAKSKLSGDNSLLSTQPL----K 660
Cdd:COG4773  542 ---------------------QVGEVRSRGVELELSGE-------LTPGLNLIAGYTYTDAKITKDADALEGKRLtnvpR 593

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 661 VIAGI--DYESPS---EKWGVFSRLTYLGakkakdAQYTVYENkgwgtplQKKVKDYpwlnksaYVFDMYGFYKPAKNLT 735
Cdd:COG4773  594 HTASLwtTYRFPSgalKGLGLGGGVRYVG------ERYGDAAN-------TFTLPSY-------TLVDAGARYDLGKNWT 653

                        810       820       830       840       850
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 488147709 736 LRAGVYNVFNRKYttWDSLRGLYSYsttnsvdrdgkgldrYRAPSRNYAVSLEWKF 791
Cdd:COG4773  654 LQLNVNNLFDKKY--YASSGSRGYV---------------YYGAPRNVRLSLSYKF 692
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 61-791 5.89e-17

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 85.16  E-value: 5.89e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   61 IKQEMIRDN-----KDLVRYSTDVGLSDS-GRHQKG-FAVRGV--EGNRVGVSIDGVNLPdseenslyarygnFNSSRLS 131
Cdd:TIGR01783   9 ITRQELEDQqagslSEALQRVPGVVVGGSgGTTQFGnITIRGFglEVDIDNVYLDGVPLL-------------SRGNLAI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  132 IDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDLLLDDRQFGVMMKNGYSTRNrewTNTLGFGvSNDRVDAALLY 211
Cdd:TIGR01783  76 VDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRTAF---DLGGPLG-ADGTFRGRLNG 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  212 SQRrghetesagNRGYAVEGEGSGANIRGSARGIP--DSSKHKYHSFLGKiaYQINDNHRIGASLNGQqgHNYTVEESYN 289
Cdd:TIGR01783 152 ARQ---------DGDSFYDGAGEETRLGATATDWQldDRTLLRLGAYYQK--ERDRGGYGGLPASGGT--SGRDLSSDRY 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  290 LTASSWREADDVNRRRnANLFYEWMPDSNW-----LSSLKADFD-YQKTKVAAVNNKGSFPMDYStwtrNYNQKDLDEIY 363
Cdd:TIGR01783 219 LGTSSNRNYDDREYLS-YGLSLEYQFNDVWtgkqnLRYSYFDTDsNQVQASGYSSDGGLFGRSLT----VVNVKQDRVQI 293

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  364 NRSMDTRFKRFTLRldsHPLQLGGGRHRLSFKTFVSRRDF-ENLNRDDYYFSGRVVRTTSSIQHPVKTTNY---GFSLSD 439
Cdd:TIGR01783 294 DAGLDGEFETGPIE---HDLLLGVSYGQRTTNRFNNTGYPsDNIYSLTATSSARTDIGDSPKDRALSSTTKalnGVALQR 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  440 QIQWnDVFSSRAGIRYDHTKMtpqelnaECHACDKTPPAANTYKGWSGFVGLAAQLNQAWHVGYDITSGYRVPNasevyf 519
Cdd:TIGR01783 371 ILLA-DKWTLTLGGRYDSVDV-------KSNNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGG------ 436

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  520 tYNHGSGNWLPNpNLKAERSTTHTLSLQGRSEKGML-DANLYQSNYRNFLSEEQklttsgtpgcteENAYYGIcsdpyke 598
Cdd:TIGR01783 437 -YYPKGAGNSGD-ILEPEKGKNYELGVRYDLGDSLLaTAALFRITKDNQLVQDP------------VNGTFSV------- 495

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  599 kldwqmkNIDKARIRGIELTGRlnvdkvaSFVPEGWKLFGSLGYAKSKLSGDNSLLSTQ-------PLKVIAGIDYESP- 670
Cdd:TIGR01783 496 -------NAGKTRNRGVELEAR-------GYLTPGLSLSAGYTYTDAEFTEDTNGDTQGntvpfvpKHTASLWASYAPPv 561

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  671 -SEKWGVFSRLTYLGAKKAKDAQytvyenkgwgtplQKKVKDYpwlnksaYVFDMYGFYKPA--KNLTLRAGVYNVFNRK 747
Cdd:TIGR01783 562 gDNGLTLGGGVQYTGKAYVDGGN-------------TGKVPSY-------TVVDLSVRYDLTkkKNLTLALNVNNLFDRD 621

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....
gi 488147709  748 YTTwdslrglYSYSTTNSVdrdgkglDRYRAPSRNYAVSLEWKF 791
Cdd:TIGR01783 622 YYT-------SGYRWGPSA-------YIYPGAPRTVGLSVSYDF 651
PRK13483 PRK13483
ligand-gated channel protein;
4-791 6.34e-17

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 85.21  E-value: 6.34e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   4 LQMLPIAALVGSIFGNPVLAADE--AATETTPVKAEIKAvrvKGQRNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGL 81
Cdd:PRK13483   6 AQVISALCLLPAVFVTHALAQAApdKTMETVVVTASGYE---QQIRDAPASISVITREDLENRFYRDLTDALLDVPGVVV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  82 SDSGRHQKgFAVRGVEGNRVGVSIDGvnlpdSEENSlyaRYGNFNSSRLSID----PEL--VRNIEIVKGADSFNTGSGA 155
Cdd:PRK13483  83 TGGGDRTD-ISLRGMGSQYTLILVDG-----KRQSS---RETRPNSDGPGVEqawtPPLaaIERIEVIRGPMSSLYGSDA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 156 LGGGVNYQTLQGRDLLLDDRQFGVMMKNGYSTRNREWTNtlgFGVSNDRVDAAL---LYSQ--RRGHETESAGNRGYAVE 230
Cdd:PRK13483 154 IGGVINIITRKVPNEWQGEVRLDTTLQENSDSGNVYQAN---FFVNGPLIKDLLglqLYGQytQREEDDIEGGYRDKDAR 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 231 gegsganirgsargipdsskhkyhSFLGKIAYQINDNHRIGASLNGQQGHnytVEESYNLTASSWREADDVNRRRNANLf 310
Cdd:PRK13483 231 ------------------------SLTAKLALTPNEDHDIMLEVGTSNQE---RDSTVGKTVAPLAPGESCGRRGCPES- 282

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 311 yewmpdsnwlsslkADFDYQKTKVAaVNNKGSFPMDYStwtRNYNQKDldEIYNRSMDTRFKRFTLRLD-SHPLqlgGGR 389
Cdd:PRK13483 283 --------------STTEYERSTVS-LSHTGRWDFGTS---DTYIQHE--EFDNKSREMKIKNTDFQSSlVAPL---GQE 339

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 390 HRLSFKTfvsrrDFENLNRDDyyfsgrvvRTTSSIQHPVKTTNYGFSLSDQIQWN--DVFSSRAGIRYDHTKmtpqelNA 467
Cdd:PRK13483 340 HTLTFGA-----AYNHQDLTD--------ETSNQISDLTDISRTQWAVFSEDEWRiaDDFALTGGLRLDHDE------NF 400

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 468 ECHAcdktppAANTYKGWsgfvglaaQLNQAWHVGYDITSGYRVPNASEVYFTYNHGS--GNWLPNPNLKAERSTTHTLS 545
Cdd:PRK13483 401 GGHV------SPRVYGVW--------NLAPSWTVKGGVSTGFRAPSLRQTTPDWGQVSrgGNIYGNPDLKPETSLNKELG 466

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 546 LQGRSEKGmLDANLyQSNYRNFlseEQKLTTSGTPG--CTEENAYYGicSDPYKEKldwqmkNIDKARIRGIELTGRLNV 623
Cdd:PRK13483 467 LYYDLGSG-LTASL-TVFYNEF---KDKITRVACPAtqCTDGPNQFG--ADPTTYV------NIDEAVTQGVEASLSYPI 533

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 624 DkvasfvpEGWKLFGSLGYAKS-KLSGDnslLSTQPLK------VIAGIDYEsPSEKWGVFSRLTYLGakkaKDAQYTvy 696
Cdd:PRK13483 534 T-------STLSLSGNYTYTDSeQKSGA---YKGSPLNqlpkhlFQASLNWE-PTDRLNSWARVNYRG----EESQPT-- 596

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 697 enkgwGTPLQKKVKdypwlnKSAYVF-DMYGFYKPAKNLTLRAGVYNVFNRKYTTWDslrglYSYSttnsvdRDGkgldr 775
Cdd:PRK13483 597 -----TGPSSSSFI------APSYTFlDLGANYQLTDNLKLSAGIYNLFDKEINYEE-----YGYV------EDG----- 649

                        810
                 ....*....|....*.
gi 488147709 776 yrapsRNYAVSLEWKF 791
Cdd:PRK13483 650 -----RRYWLGMTYSF 660
PRK13513 PRK13513
ligand-gated channel protein;
275-753 1.58e-15

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 80.58  E-value: 1.58e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 275 NGQQGHNYTVEESYNLTASSWREADDVNRRRNANLfyewmpDSNWLSSlkaDFDYQKTKVAAVNNkGSFpmDYSTWTrNY 354
Cdd:PRK13513 233 NGTATFSLTPDDNNEFDFEIGRYVQDRNSTPGRTL------ALNGTNS---DTQYDRNNYAITHN-GYY--DFGNST-SY 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 355 NQKDldEIYN--RSM---DTRFKRFT-LRLDSHPLQLGGgrhrlsfktfvsRRDFENLnRDDyyfsGRVVRTTSSIQhpv 428
Cdd:PRK13513 300 IQRD--ETRNpsRQMksvDTIFNTQTsFLLDDHTLSLGG------------QYRYEEL-YDK----GNQLPSASDLN--- 357

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 429 KTTNYGFSL--SDQIQWNDVFSSRAGIRYDhtkmtpQELNAECHAcdkTPpaaNTYKGWSgfvglaaqLNQAWHVGYDIT 506
Cdd:PRK13513 358 KLTRWSWALfaEDEWQMTNDFALTGGIRMD------QDQNYGTHW---TP---RLYGVWH--------LADQWTLKGGVS 417

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 507 SGYRVPNasevyftYNHGSGNW-------------LPNPNLKAERSTTHTLSLQGRSEKGM-LDANLYQSNYRNFLSEEQ 572
Cdd:PRK13513 418 TGYRSPD-------LRQATDNWgqltgggglpaliLGNSDLKPEKSISQEIGILWDNQENLnASVTLFNTDFKDKITEVR 490

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 573 K-LTTSGTPGCTEENAYYGICSDpykekldwqMKNIDKARIRGIELTgrLNVDkvasfVPEGWKLFGSLGYAKS-KLSGD 650
Cdd:PRK13513 491 NcDTTNTDGQCVFNGINYDFISD---------RINVDKANMRGVEAT--FNWD-----INQAWSLATNYTFTQSeQKSGA 554

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 651 nslLSTQPLKVI------AGIDYESpSEKWGVFSRLTYLGakkaKDAQYTVYENKGWGTPlqkkvkdypwlnksAYVF-D 723
Cdd:PRK13513 555 ---FAGQPLNQMpkhmanATLNWQT-TEDFATWIRINYRG----KTSEYLNRTSMGSGTP--------------SYTFvD 612

                        490       500       510
                 ....*....|....*....|....*....|..
gi 488147709 724 MYGFYKPAKNLTLRAGVYNVFNRK--YTTWDS 753
Cdd:PRK13513 613 LGASYQLTKELRLMGGVYNLLDKRvdIDVNDK 644
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 46-158 5.36e-15

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 71.53  E-value: 5.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   46 QRNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDS-GRHQKGFAVRGVEGNRVGVSIDGVNLPDSeenslyaryGN 124
Cdd:pfam07715   2 LRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVSSGgGGGGSSISIRGFGSNRVLVLVDGVPLNSG---------GG 72

                          90       100       110
                  ....*....|....*....|....*....|....
gi 488147709  125 FNSSRLSIDPELVRNIEIVKGADSFNTGSGALGG 158
Cdd:pfam07715  73 GSVDLNSIDPEDIERVEVLKGPASALYGSGAIGG 106
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
46-355 8.29e-15

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 75.68  E-value: 8.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  46 QRNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGR--HQKGFAVRGVEGNRVGVSIDGVNLpdseeNSLYARYG 123
Cdd:COG4206   12 KSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSSGGpgSAASISIRGLGSNQTLVLIDGVPL-----NDPSLGGV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 124 NFNSsrlsIDPELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRdlllDDRQFGVMMKNG-YSTRNrewtNTLGFGVSN 202
Cdd:COG4206   87 DLSL----IPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGK----KGFKGSVSASYGsFGTRR----LSASLSGGA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 203 DRVDAALLYSQRRghetesagnrgyavegegsGANIRGSARGIPDSSKHKYHSFLGKIAYQINDNHRIGASLNGQQGHNy 282
Cdd:COG4206  155 GKFSYSLSASYRR-------------------SDGYRYNDPDLRNNDGYENTSLNARLGYKLGDNGSLSLSGGYSDSER- 214

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488147709 283 tveesynltasSWREADDVNRRRNANLFYEWMPDSNWLSSLKADFDYQKTKVAAVNNkGSFPMDYSTWTRNYN 355
Cdd:COG4206  215 -----------GYPGAVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGD-SAGTSNTDGARAGLS 275
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 20-791 1.23e-11

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 68.37  E-value: 1.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  20 PVLAADEAAtETTPVKAEIKAVRVKgqrNAPAAVERVNLNRIKQEMIRDNKDLVRYSTDVGLSDSGRHQKGFAVRGVEGN 99
Cdd:PRK10064  22 PVLAVDDDG-ETMVVTASAVEQNLK---DAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSS 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 100 RVGVSIDGVNLpdSEENSLYaRYGNFNSSRLSIDPelVRNIEIVKGADSFNTGSGALGGGVNYQTlqgrdlllddRQFGV 179
Cdd:PRK10064  98 YTLILIDGKRV--NSRNAVF-RHNDFDLNWIPVDA--IERIEVVRGPMSSLYGSDALGGVVNIIT----------KKIGQ 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 180 MMKNGYST-------RNREWTNTLGFGVSNDRVDAAL---LYSQRRGHETESAGNRGYAVEGEGSgaNIRGsargipdss 249
Cdd:PRK10064 163 KWHGTVTVdttiqehRDRGDTYNGQFFTSGPLIDGVLgmkAYGSLAKREKDDPQNSTTTDTGETP--RIEG--------- 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 250 khkyhsflgkiaYQINDNHrIGASLNGQQGHNYTVEESYNltaSSWREADDVNRRRNANLFYEWMPDSNWlsslkaDFDY 329
Cdd:PRK10064 232 ------------FTSRDGN-VEFAWTPNQNHDFTAGYGFD---RQDRDSDSLDKNRLERQNYSLSHNGRW------DYGN 289

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 330 QKTKVaavnnkgsfpmdYSTWTRNYNQKDLDEI--YNRSMDtrfKRFTLRLD--SHPLQLGG-GRHRlsfktfvSRRDFE 404
Cdd:PRK10064 290 SELKY------------YGEKVENKNPGNSSPItsESNSID---GKYTLPLTaiNQFLTFGGeWRHD-------KLSDAV 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 405 NLnrddyyfsgrvvrtTSSIQHPVKTTNYGFSLSDQIQWNDVFSSRAGIRYDHTKmtpqelnaechacdktppaanTY-K 483
Cdd:PRK10064 348 NL--------------TGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHE---------------------TYgD 392

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 484 GWSGFVGLAAQLNQAWHVGYDITSGYRVPNASEVyftynhgSGNWLPN-----------PNLKAERSTTHTLSLQGRSEK 552
Cdd:PRK10064 393 HWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQL-------SPDWTSNscrgackivgsPDLKPETSESWELGLYYMGEE 465

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 553 GMLDA-----NLYQSNYRNFLSEEQKLTTSGTPGCTEenaYYGICSDPYKEKLD-WQMKNIDKARIRGIELTGRLNVDkv 626
Cdd:PRK10064 466 GWLEGvessvTVFRNDVDDRISISRTSDVNAAPGYQN---FVGFETNGRGRRVPvFRYYNVNKARIQGVETELKIPFN-- 540

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 627 asfvpEGWKLFGSLGY--AKSKLSGDNSLLSTQPLKVIAG-IDYESP-SEKWGVFSRLTYLGAKKAkdaqytvyenkgwG 702
Cdd:PRK10064 541 -----DEWKLSLNYTYndGRDVSNGENKPLSDLPFHTANGtLDWKPLaLEDWSFYVSGNYTGQKRA-------------D 602

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 703 TPLQKKVKDYpwlnksaYVFDMYGFYKPAKNLTLRAGVYNVFNRkyttwDSLRGLYSYSttnsvdRDGkgldryrapsRN 782
Cdd:PRK10064 603 SATAKTPGGY-------TIWNTGAAWQVTKDVKLRAGVLNLGDK-----DLSRDDYSYN------EDG----------RR 654


                 ....*....
gi 488147709 783 YAVSLEWKF 791
Cdd:PRK10064 655 YFMAVDYRF 663
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
2-660 6.32e-11

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 65.80  E-value: 6.32e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709   2 KPLQMLPIAALVGSIFGNPvLAADEAATETTPVKAEIKAvrvKGQRNAPAAVERVNLNRIKQEMIRDNKDLVRystDV-G 80
Cdd:PRK13484   4 KYIIAPGIAVMCSAVISSG-YASSDKKEDTLVVTASGFT---QQLRNAPASVSVITSEQLQKKPVSDLVDAVK---DVeG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  81 LSDSGRHQK-GFAVRGVEGNRVGVSIDG--VNLPDSEENSLYARYGNFnssrlsIDP-ELVRNIEIVKGADSFNTGSGAL 156
Cdd:PRK13484  77 ISITGGNEKpDISIRGLSGDYTLILVDGrrQSGRESRPNGSGGFEAGF------IPPvEAIERIEVIRGPMSSLYGSDAI 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 157 GGGVNYQTLQGRDLLLDdrqfGVMMKNGYSTRNREWTNTlgfgVSNDRVDAALLYSQRRGheTESAGNRGYAVEGEGSGA 236
Cdd:PRK13484 151 GGVINIITKPVNNQTWD----GVLGLGGIIQEHGKFGNS----TTNDFYLSGPLIKDKLG--LQLYGGMNYRKEDSISQG 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 237 NIRGSARGIPdsskhkyhsflGKIAYQINDNHRI--GASLNGQQgHNYTVEESynLTASSWR-EADDVNRRRNANlfyew 313
Cdd:PRK13484 221 TPAKDNKNIT-----------ATLQFTPTESQKFvfEYGKNNQV-HTLTPGES--LDAWTMRgNLKQPNSKRETH----- 281

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 314 MPDSNWLSSLKADFD--------YQKTKVAAVNNKGSfpMDYSTWTRNYNQKDlDEIYNRSMDTRFKRFtlrLDSHPLQL 385
Cdd:PRK13484 282 NSRSHWVAAWNAQGEilhpeiavYQEKVIREVKSGKK--DKYNHWDLNYESRK-PEITNTIIDAKVTAF---LPENVLTI 355

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 386 GGGRHRLSFktfvsrrdfenlnRDDYYFSGRVVRTTSsiqhpVKTTNYGFSLSDQIQWNDVFSSRAGIRYDhtkmtpqel 465
Cdd:PRK13484 356 GGQFQHAEL-------------RDDSATGKKTTETQS-----VSIKQKAVFIENEYAATDSLALTGGLRLD--------- 408

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 466 NAECHACDKTPPAANTYkgwsgfvglaaQLNQAWHVGYDITSGYRVPNASEV---YFTYNHGSGNWL-PNPNLKAERSTT 541
Cdd:PRK13484 409 NHEIYGSYWNPRLYAVY-----------NLTDNLTLKGGIAKAFRAPSIREVspgFGTLTQGGASIMyGNRDLKPETSVT 477

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 542 HTLSLQGRSEKGM-LDANLYQSNYRNflseeqKLTTsgtpgcteenayYGICS-DPYKEKLDWQMKNIDKARIRGIELTg 619
Cdd:PRK13484 478 EEIGIIYSNDSGFsASATLFNTDFKN------KLTS------------YDIGTkDPVTGLNTFIYDNVGEANIRGVELA- 538

                        650       660       670       680
                 ....*....|....*....|....*....|....*....|.
gi 488147709 620 rlnvdkVASFVPEGWKLFGSLGYAKSKLSGDNSLLSTQPLK 660
Cdd:PRK13484 539 ------TQIPVYDKWHVSANYTFTDSRRKSDDESLNGKSLK 573
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
485-791 6.60e-08

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 56.19  E-value: 6.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 485 WSGFVGLAAQLNQAWHVGYDITSGYRVPN---ASEVYFTYNHGSG--NWLP-------NPNLKAERSTTHTLSLQgrSEK 552
Cdd:PRK13524 465 WSPSLNLSQGLGDDFTLKMGIARAYKAPNlyqTNPNYILYSKGQGcyASAGngcylqgNDDLKAETSVNKEIGLE--FKR 542

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 553 GMLDANL--YQSNYRNFLseEQKLTTSGTPGCTEENAYygicsdpykekldwQMKNIDKARIRGIEltGRLNVDkvasfV 630
Cdd:PRK13524 543 DGWLAGLtwFRNDYRNKI--EAGYVPVGTNSVGKTDIY--------------QWENVPKAVVEGLE--GTLNVP-----V 599

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 631 PEGWKLFGSLGY---AKSKLSGDnsllstqPLKVI------AGIDYEsPSEKWGVFSRLTYLGAKKAKdaQYTVYENKGW 701
Cdd:PRK13524 600 SETVNWTNNLTYmlqSKNKTTGD-------PLSIIpeytlnSTLSWQ-ATEDLSLQSTFTWYGKQKPK--KYNYKGQPVT 669

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 702 GTPLQKKvkdypwlnkSAY-VFDMYGFYKPAKNLTLRAGVYNVFNRKYttwdsLRGLYSYSTTNSVdrDGKGLDRYRAPS 780
Cdd:PRK13524 670 GSATKEV---------SPYsIVGLSATYDVTKNVSLTGGVDNLFDKRL-----WREGNAQTTGDLI--AGAGAYTYNEPG 733

                        330
                 ....*....|.
gi 488147709 781 RNYAVSLEWKF 791
Cdd:PRK13524 734 RTYYMSLNTHF 744
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
93-619 9.45e-07

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 52.30  E-value: 9.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709  93 VRGVEGNRVGVSIDGVNLpdseenslyARYGNFNSSRLSIDP-ELVRNIEIVKGADSFNTGSGALGGGVNYQTLQGRDLL 171
Cdd:PRK10641  88 IRGTNSSHVLVLIDGVRL---------NQAGISGSADLSQIPiSLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGT 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 172 LDDRQFGvmmKNGYSTRNREWTNTLGfgvSNDRVDAALLYSQRRGHETESAGNRGYAvegegsganirgsargiPDSSKH 251
Cdd:PRK10641 159 TLSAGWG---SNGYQNYDGSTQQQLG---DNTRVTLAGDYTYTKGFDVVAYGNTGTQ-----------------AQPDRD 215

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 252 KYHS--FLGKIAYQINDNhrigasLNG-QQGHNYTVEESYNLTASSWREADDV----NRRRNANLFYEwmpDSNWLSSLK 324
Cdd:PRK10641 216 GFMSktLWGGLEHQFNDQ------WSGfVRGYGYDNRTDYDAYYSPGSPLIDTrqlySQSWDAGLRYN---GGIYSSQLI 286

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 325 AdfDYQKTKvaavnnkgsfpmDYstwtrNYnqkdlDEIYNR-----SMDtRFKRFTLRLdSHPLQLGGGrhrlsfkTFVS 399
Cdd:PRK10641 287 A--SYSHSK------------DY-----NY-----DPHYGRydssaTLD-DMKQYNVQW-GNTVQVGHG-------NISA 333

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 400 RRDFENlnrddyyfsGRVVRTTSSIQHPVKTTNYGFSLSDQIQWNDVfSSRAGIRYDHtkmtpqelnaechacdktppaa 479
Cdd:PRK10641 334 GVDWQK---------QTTTPGTGYVPDGYDQRNTGIYLTGQQQIGDV-TLEGAARSDD---------------------- 381

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488147709 480 NTYKGWSGfvglAAQLNQAWHV--GYDIT----SGYRVPNASEVYFTYNhgsgnwlpNPNLKAERSTTHTLSLQGRSekG 553
Cdd:PRK10641 382 NSQFGWHG----TWQTSAGWEFidGYRFIasygTAFKAPNLGQLYGFYG--------NPNLKPEESKQWEGGFEGLT--G 447

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488147709 554 MLDANLyqSNYRNflsEEQKLTTSGtpgcTEENAYYgicsdpykekldwqmkNIDKARIRGIELTG 619
Cdd:PRK10641 448 PVNWRL--SGYRN---DIDNLIDYD----DHTLKYY----------------NVGKATIKGVEWTG 488
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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