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Conserved domains on  [gi|488148454|ref|WP_002219662|]
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Maf family nucleotide pyrophosphatase [Neisseria meningitidis]

Protein Classification

Maf family protein; non-canonical purine NTP pyrophosphatase( domain architecture ID 10794000)

multicopy associated filamentation (Maf) family protein is a nucleotide binding protein involved in septum formation and may also have a role as a house-cleaning NTP pyrophosphatase| RdgB/HAM1 family pyrophosphatase that hydrolyzes non-canonical purine nucleotides to their respective monophosphates and prevents their incorporation into DNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14367 PRK14367
Maf-like protein; Provisional
 1-201 1.66e-147

Maf-like protein; Provisional


:

Pssm-ID: 237692  Cd Length: 202  Bit Score: 407.92  E-value: 1.66e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   1 MNTLYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFCETNGTMPDFPLITADTCVV 80
Cdd:PRK14367   1 MNTLYLGSNSPRRMEILTQLGYRVVKLPAGIDETVKAGETPARYVQRMAEEKNRTALTLFCETNGTMPDFPLITADTCVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  81 SDGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160
Cdd:PRK14367  81 SDGIILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 488148454 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRTP-PFIRA 201
Cdd:PRK14367 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRSPlSALKP 202
 
Name Accession Description Interval E-value
PRK14367 PRK14367
Maf-like protein; Provisional
 1-201 1.66e-147

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 407.92  E-value: 1.66e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   1 MNTLYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFCETNGTMPDFPLITADTCVV 80
Cdd:PRK14367   1 MNTLYLGSNSPRRMEILTQLGYRVVKLPAGIDETVKAGETPARYVQRMAEEKNRTALTLFCETNGTMPDFPLITADTCVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  81 SDGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160
Cdd:PRK14367  81 SDGIILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 488148454 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRTP-PFIRA 201
Cdd:PRK14367 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRSPlSALKP 202
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 4-196 1.09e-87

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 255.73  E-value: 1.09e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCVVSDG 83
Cdd:COG0424    3 LILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARL-------PDALVLGADTVVVLDG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  84 IILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRG-KTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIG 162
Cdd:COG0424   76 RILGKPADAEEARAMLRRLSGRTHRVHTGVALIDPGgRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLG 155

                        170       180       190
                 ....*....|....*....|....*....|....
gi 488148454 163 GIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRTP 196
Cdd:COG0424  156 AALVERIEGSYSNVVGLPLIELLELLRELGVDLL 189
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 4-188 4.88e-84

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 246.23  E-value: 4.88e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtMPDFPLITADTCVVSDG 83
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARL------PPDALVIGADTVVVLDG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  84 IILGKPRSQAEAATFLNLLSGTGHTVLTAVC-IHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIG 162
Cdd:cd00555   75 RILGKPKDREEAREMLKRLSGRTHEVYTGVAlIDPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLG 154

                        170       180
                 ....*....|....*....|....*.
gi 488148454 163 GIFIQSIEGSFSGIMGLPVYETVSML 188
Cdd:cd00555  155 GALIERIEGDYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 4-191 1.51e-74

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 221.89  E-value: 1.51e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454    4 LYLGSNSPRRMEILTQLGYRVIQLPAGIDES-VKAGETPFAYVQRMAEEKnrtALTLfcetngtmpdfpLITADTCVVsd 82
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETpLKEDPAPEEYVLRLARAK---AEAL------------VIGADTVVV-- 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   83 gIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTS---SRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQ 159
Cdd:pfam02545  64 -LILGKPKDEEEARAMLKRLSGRTHEVYTGVALINPGGGTggvSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQ 142

                         170       180       190
                  ....*....|....*....|....*....|..
gi 488148454  160 GIGGIFIQSIEGSFSGIMGLPVYETVSMLQDL 191
Cdd:pfam02545 143 GLGAALVERIEGDYSNVVGLPLIELLRLLREL 174
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 3-189 6.62e-53

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 167.57  E-value: 6.62e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454    3 TLYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCVVSD 82
Cdd:TIGR00172   4 ELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELL-------ADALIIGADTVVILD 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   83 GIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIG 162
Cdd:TIGR00172  77 GEIYGKPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFG 156

                         170       180
                  ....*....|....*....|....*..
gi 488148454  163 GIFIQSIEGSFSGIMGLPVYETVSMLQ 189
Cdd:TIGR00172 157 APLIKKIDGDYSNVVGLPLEKLLGALR 183
 
Name Accession Description Interval E-value
PRK14367 PRK14367
Maf-like protein; Provisional
 1-201 1.66e-147

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 407.92  E-value: 1.66e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   1 MNTLYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFCETNGTMPDFPLITADTCVV 80
Cdd:PRK14367   1 MNTLYLGSNSPRRMEILTQLGYRVVKLPAGIDETVKAGETPARYVQRMAEEKNRTALTLFCETNGTMPDFPLITADTCVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  81 SDGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160
Cdd:PRK14367  81 SDGIILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 488148454 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRTP-PFIRA 201
Cdd:PRK14367 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRSPlSALKP 202
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 4-196 1.09e-87

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 255.73  E-value: 1.09e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCVVSDG 83
Cdd:COG0424    3 LILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARL-------PDALVLGADTVVVLDG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  84 IILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRG-KTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIG 162
Cdd:COG0424   76 RILGKPADAEEARAMLRRLSGRTHRVHTGVALIDPGgRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLG 155

                        170       180       190
                 ....*....|....*....|....*....|....
gi 488148454 163 GIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRTP 196
Cdd:COG0424  156 AALVERIEGSYSNVVGLPLIELLELLRELGVDLL 189
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 4-188 4.88e-84

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 246.23  E-value: 4.88e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtMPDFPLITADTCVVSDG 83
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARL------PPDALVIGADTVVVLDG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  84 IILGKPRSQAEAATFLNLLSGTGHTVLTAVC-IHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIG 162
Cdd:cd00555   75 RILGKPKDREEAREMLKRLSGRTHEVYTGVAlIDPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLG 154

                        170       180
                 ....*....|....*....|....*.
gi 488148454 163 GIFIQSIEGSFSGIMGLPVYETVSML 188
Cdd:cd00555  155 GALIERIEGDYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 4-191 1.51e-74

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 221.89  E-value: 1.51e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454    4 LYLGSNSPRRMEILTQLGYRVIQLPAGIDES-VKAGETPFAYVQRMAEEKnrtALTLfcetngtmpdfpLITADTCVVsd 82
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETpLKEDPAPEEYVLRLARAK---AEAL------------VIGADTVVV-- 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   83 gIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTS---SRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQ 159
Cdd:pfam02545  64 -LILGKPKDEEEARAMLKRLSGRTHEVYTGVALINPGGGTggvSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQ 142

                         170       180       190
                  ....*....|....*....|....*....|..
gi 488148454  160 GIGGIFIQSIEGSFSGIMGLPVYETVSMLQDL 191
Cdd:pfam02545 143 GLGAALVERIEGDYSNVVGLPLIELLRLLREL 174
PRK00648 PRK00648
Maf-like protein; Reviewed
 4-192 4.78e-57

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 178.18  E-value: 4.78e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLG--YRVIQLPAgIDESVKAGETPFAYVQRMAEEKNRtaltlfcETNGTM-PDFPLITADTCVV 80
Cdd:PRK00648   5 IILASSSPRRKEILEGFRipFEVVPSPF-VEESYPYSLDPEEITLELARLKAE-------AVRSDLfPDELIITADTIVW 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  81 SDGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160
Cdd:PRK00648  77 YDGKVLGKPKDEEEAVEMLRTLSGKTHEVITGVCLLHNGKLLSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGIQE 156

                        170       180       190
                 ....*....|....*....|....*....|..
gi 488148454 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLG 192
Cdd:PRK00648 157 WGGLIVKKIEGSYYNVMGLPIQTLYEELKELG 188
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 3-189 6.62e-53

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 167.57  E-value: 6.62e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454    3 TLYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCVVSD 82
Cdd:TIGR00172   4 ELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELL-------ADALIIGADTVVILD 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   83 GIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIG 162
Cdd:TIGR00172  77 GEIYGKPKDKEEAAEFLRKLSGQEHEVYTAVALIDSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFG 156

                         170       180
                  ....*....|....*....|....*..
gi 488148454  163 GIFIQSIEGSFSGIMGLPVYETVSMLQ 189
Cdd:TIGR00172 157 APLIKKIDGDYSNVVGLPLEKLLGALR 183
PRK14368 PRK14368
Maf-like protein; Provisional
 6-192 3.77e-51

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 163.41  E-value: 3.77e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   6 LGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLfceTNGTMpdfpLITADTCVVSDGII 85
Cdd:PRK14368   9 LASASPRRSELLASAGIEFDVVPADIPEEPLPGEEPVDHVLRLAREKARAAAAL---AEGRF----FIGADTIVVCDGEI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  86 LGKPRSQAEAATFLNLLSGTGHTVLTAVCIH--YRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIGG 163
Cdd:PRK14368  82 MGKPKDEADAVRMLKKLSGVPHEVITGFAVYdrERDGCVTKAVRTKVFFKPLRDEEIRDYIATGCPMDKAGAYAIQGGAA 161

                        170       180
                 ....*....|....*....|....*....
gi 488148454 164 IFIQSIEGSFSGIMGLPVYETVSMLQDLG 192
Cdd:PRK14368 162 HMVRKIDGSYTNVVGLPLCEVVEALRTIG 190
PRK14364 PRK14364
Maf-like protein; Provisional
 6-189 1.03e-50

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 162.09  E-value: 1.03e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   6 LGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCVVSDGII 85
Cdd:PRK14364   1 LASSSPRRRELLQQLGLNFEIYSPDIDESVHEGELVHQYVERLAREKAQAVLNIF-------PDSVIIAADTSLGLDGQI 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  86 LGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIGGIF 165
Cdd:PRK14364  74 IGKPDSKQHAFDIWKQLSGRWHDVFSGICIATQQQILSQVVQTQVEFASLTTQDMEDYWATGEPVGKAGAYAIQGIASQY 153

                        170       180
                 ....*....|....*....|....
gi 488148454 166 IQSIEGSFSGIMGLPVYETVSMLQ 189
Cdd:PRK14364 154 IPKIQGSYSNVVGLPLYEFSQLFK 177
PRK01441 PRK01441
Maf-like protein; Reviewed
 4-193 4.24e-47

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 153.72  E-value: 4.24e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLGYRVIQL-PAGIDESVKAGETPFAYVQRMAEEKNRTALTLFCETNGTMPDFpLITADTCVVSD 82
Cdd:PRK01441   7 LVLASGSPRRVELLNQAGIEPDRLmPADIDETPKRAEHPRSLARRLSREKAEAALEALQGDDDWRGAY-ILAADTVVAVG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  83 GIILGKPRSQAEAATFLNLLSGTGHTVLTAVC-IHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGI 161
Cdd:PRK01441  86 RRILPKAELVDEASQCLRLLSGRNHRVYTGVClVTPDGKLRQKLVETRVRFKRLSREDIEAYLASGEWRGKAGGYAIQGI 165

                        170       180       190
                 ....*....|....*....|....*....|..
gi 488148454 162 GGIFIQSIEGSFSGIMGLPVYETVSMLQDLGY 193
Cdd:PRK01441 166 AGSFVVKLVGSYTNVVGLPLYETVSLLAGEGF 197
PRK04694 PRK04694
Maf-like protein; Reviewed
 4-192 3.41e-45

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 148.19  E-value: 3.41e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLG--YRVIQLPagIDESVKAGETPFAYVQRMAEEKNRTALTLfceTNGTMPDFPLITADTCVVS 81
Cdd:PRK04694   2 LYLASRSPRRRELLQRLDvpFQTLQLD--VPEVRAADESPDHYVQRVALEKAHAGLAL---VQAADADAIVLGSDTEVVL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  82 DGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQT-NRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160
Cdd:PRK04694  77 GERVFGKPVDVDDAIAMLRALSGRTHQVLTAVVLVCAQRAPAQALVvSEVTFDLLDDAQIAAYAASGEPMGKAGAYAIQG 156

                        170       180       190
                 ....*....|....*....|....*....|..
gi 488148454 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLG 192
Cdd:PRK04694 157 RAERFIRHLSGSYSGVMGLPLYQTSQLLTAFG 188
PRK14362 PRK14362
Maf-like protein; Provisional
 4-196 1.99e-43

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 144.23  E-value: 1.99e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLG--YRVIqLPAGIDESVKAGETPFAYVQRMAEEKNRTALtlfcetnGTMPDFPLITADTCVVS 81
Cdd:PRK14362  14 VVLASGSPRRREFLEQMGlpFEVI-LPGAAEPSPIEGEQPEAYARRAAEAKARAVA-------ADHAGRLVIAADTVVAL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  82 DGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQ-TNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG 160
Cdd:PRK14362  86 DGMILGKPADRADALSMLRRLAGRTHEVVSACCVVLPDGGREVFHaITRVTMWDWPEAALAAYVATGEPSDKAGAYGIQG 165

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 488148454 161 IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRTP 196
Cdd:PRK14362 166 IGAFLVRSIEGSWSNVVGLPVAELTALLLRRGVILP 201
PRK14365 PRK14365
Maf-like protein; Provisional
 1-192 2.51e-42

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 141.11  E-value: 2.51e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   1 MNTLYLGSNSPRRMEILTQL-GYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCV 79
Cdd:PRK14365   1 MRRIILASASPRRKELLKQLiGDNFLVYPSSYEEPPQPGLDPEELLLKHSLEKARDVAKHF-------DSGIIISADTSV 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  80 VSDGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCI--HYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYA 157
Cdd:PRK14365  74 FCNGEVLGKPASPENAEEMLEKLSGRKFLVITGLTVldLDSGKEISEIESTDVWMTELSREQILAYVRTGEPLDKAGAFA 153

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 488148454 158 VQGIGGIFIQSIEGSFSGIMGLPVYETVSMLQDLG 192
Cdd:PRK14365 154 IQGKGAVLVEKIEGDFFNVVGLPLFRLGKILEKLG 188
PRK14366 PRK14366
Maf-like protein; Provisional
 1-188 6.08e-40

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 134.93  E-value: 6.08e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   1 MNTLYLGSNSPRRMEILTQLGYRVIQ-LPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCV 79
Cdd:PRK14366   4 FDNLILASSSKQRLALLEQIGVVPGEiVSPDIDESPLKKELPKDYSIRMAKEKAEKVQSLR-------PDKFVLGADTVV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  80 VSDGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHY-RGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAV 158
Cdd:PRK14366  77 CCGRRILLKAETEEQAEEYLELLSGRRHRVYTSVCLYTpGGKLHIRSVVTVVKFKRLSKQEIKYYIASGEWKGKAGGCNI 156

                        170       180       190
                 ....*....|....*....|....*....|
gi 488148454 159 QGIGGIFIQSIEGSFSGIMGLPVYETVSML 188
Cdd:PRK14366 157 QGLAGKFVLSINGSYSSIIGLPLHETYCLL 186
PRK00078 PRK00078
Maf-like protein; Reviewed
 6-192 1.43e-39

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 133.70  E-value: 1.43e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   6 LGSNSPRRMEILTQLGYRVIQLPAGIDESvkagETPF-----AYVQRMAEEKNRTALTLFCETNGTmpdfpLITADTCVV 80
Cdd:PRK00078   5 LASASERRQELLKRILEDFQVIVSDFDES----SVPFkgnieSYVMNLAEGKARSVSKKLDQESSI-----VIGCDTIVA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  81 SDGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCI--HYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAV 158
Cdd:PRK00078  76 FNGKVLGKPKDEEDAFEMLKALSGNEHEVYSGIAIldTKSNKIIKDFVCTEVKFSKLTDRQIRKYINTGEPMDKAGAYGI 155

                        170       180       190
                 ....*....|....*....|....*....|....
gi 488148454 159 QGIGGIFIQSIEGSFSGIMGLPVYETVSMLQDLG 192
Cdd:PRK00078 156 QGKGGVFVEEINGCYYNVVGLPLNKLYKMLEEMG 189
PRK14361 PRK14361
Maf-like protein; Provisional
 6-192 1.17e-36

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 126.20  E-value: 1.17e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   6 LGSNSPRRMEILTQLGYRVIQLPAGIDESvkAGET-PFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCVVSDGI 84
Cdd:PRK14361   3 LASGSPRRRELLENLGVPFQVVVSGEAED--STETdPARLAAELALLKARAVARLH-------PDAVVIAADTVVALGGV 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  85 ILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIGGI 164
Cdd:PRK14361  74 LLAKPADEAENEAFLRVLSGRTHQVYTGVAVLSRGTEQVGVERTDVTFRALTAAEISFYARSGEGLDKAGGYGIQGVGMA 153

                        170       180
                 ....*....|....*....|....*...
gi 488148454 165 FIQSIEGSFSGIMGLPVYETVSMLQDLG 192
Cdd:PRK14361 154 LVSRVEGDYSNVVGFPLSLVIRLLRGAG 181
PRK14363 PRK14363
Maf-like protein; Provisional
 4-181 8.61e-34

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 119.23  E-value: 8.61e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKagETPFAYVQRMAEEKnrtALTLFceTNGTMPDFPLITADTCVVSDG 83
Cdd:PRK14363   3 IILASSSPRRRQLMELLGIEFEVEKPDVEEEFL--ESPEETVRELSLRK---AEWVF--KKRKEEEILVIGSDTVVVLDG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  84 IILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGIGG 163
Cdd:PRK14363  76 NILGKPESLEEAKGMLKKLSGRWHVVYTGVAFVSSETKDVIVSSTKVRFRELPESVIDYYVEKYRPLDKAGAYGIQDFAA 155

                        170
                 ....*....|....*...
gi 488148454 164 IFIQSIEGSFSGIMGLPV 181
Cdd:PRK14363 156 VFVEKIEGDFFTVVGFPL 173
PRK04056 PRK04056
septum formation inhibitor Maf;
4-181 8.07e-30

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 108.51  E-value: 8.07e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLGYRVIQLPAGIDESVKAGETPFAYVQRMAEEKNRTALTLFCEtngtmpDFPLITADTCVVSDG 83
Cdd:PRK04056   2 IILASSSSTRANLLKEAGIEFEQKSLDFDEESIKKTSPKEFVYLAVKGKLEQFLKKYGN------ECNLLVADSVVSCGN 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  84 IILGKPRSQAEAATFLNLLSGTGHTVLTavCIHYRGKTS--SRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQGI 161
Cdd:PRK04056  76 KILRKAKDKEEAREMLKLQSGNEISVLT--CMILKSPEKewLDLSVTTYRFKKFDEDDLEKYLESGLWQGKAGACMVEGF 153

                        170       180
                 ....*....|....*....|
gi 488148454 162 GGIFIQSIEGSFSGIMGLPV 181
Cdd:PRK04056 154 HKKYIKSVSGNESTAMGLNV 173
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 4-132 8.65e-29

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 104.12  E-value: 8.65e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLG-YRVIQLPAGIDESVKAGEtPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITADTCVVSD 82
Cdd:cd00985    1 LILASGSPRRLEELKQIGgIEFEVLPSDIDETGLKGE-PEDTVEELALLKARAVAERL-------PDAPVIADDTGLVVD 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488148454  83 GIILGKPRSQAEAATFLNLLSGTGHTVLTAVC-IHYRGKTSSRVQTNRVVF 132
Cdd:cd00985   73 GRPGGKPARFAEALEMLRGLSGRTAEFVTAVAlVDPDGKIITFEGETEGKI 123
PRK02141 PRK02141
Maf-like protein; Reviewed
 4-198 2.09e-21

Maf-like protein; Reviewed


Pssm-ID: 235009  Cd Length: 207  Bit Score: 87.12  E-value: 2.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   4 LYLGSNSPRRMEILTQLG--YRVIqLPAgIDESVKAGETPFAYVQRMAEEKNRTAltlfCETNGTMPDFPLITADTCVVS 81
Cdd:PRK02141  11 LILASSSRYRRELLERLRlpFDVV-SPD-IDETPLAGETPAATALRLAAAKARAV----AATIDAPPGALVIGSDQVATF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  82 DGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIhYRGKT----SSRVQTnRVVFKPLSSEEISAYVQSGEPMDKAGAYA 157
Cdd:PRK02141  85 DGLQIGKPGTHERALAQLQAMRGRTVEFHSALCL-YDSRTgetqSEDVVT-RVRFRTLTDAELDAYLRAETPYDVAGSAK 162

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 488148454 158 VQGIGGIFIQSIEGSF-SGIMGLPVYETVSMLQDLGYrtPPF 198
Cdd:PRK02141 163 SEGLGIALLDAIDSDDpTALVGLPLIALTRMLRAAGY--PLF 202
PRK02478 PRK02478
Maf-like protein; Reviewed
 3-192 1.11e-16

Maf-like protein; Reviewed


Pssm-ID: 167380  Cd Length: 199  Bit Score: 74.39  E-value: 1.11e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454   3 TLYLGSNSPRRMEILTQLGYRVIQLPAGIDESV------KAGETPFAYVQRMAEEKNRTALTLFcetngtmPDFPLITAD 76
Cdd:PRK02478   4 KLILASKSPFRRALLENAGLEFSAAAADIDERAveapleESGATPEDVALVLAEAKAIDVSERF-------PGALVIGCD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488148454  77 TCVVSDGIILGKPRSQAEAATFLNLLSGTGHTVLTAVCIHYRGKTSSR-VQTNRVVFKPLSSEEISAYVQS-GE-PMDKA 153
Cdd:PRK02478  77 QTMSLGDEVFHKPKDMEEARRHLQKLSGKTHQLNSAVVLVRDGKVLWRhVSIAHMTMRDLDAGFIGRHLARvGEkALSSV 156

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 488148454 154 GAYAVQGIGGIFIQSIEGSFSGIMGLPVYETVSMLQDLG 192
Cdd:PRK02478 157 GAYQLEGEGIQLFEKIEGDYFTILGLPLLPLLAKLRELG 195
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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