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Conserved domains on  [gi|488155284|ref|WP_002226492|]
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heme biosynthesis protein HemY [Neisseria meningitidis]

Protein Classification

heme biosynthesis protein HemY( domain architecture ID 11489224)

heme biosynthesis protein HemY similar to Escherichia coli HemY, is found in heme biosynthesis gene clusters and contains tetratricopeptide repeats (TPRs)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR_hemY_coli TIGR00540
heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized ...
 20-389 2.91e-110

heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General]


:

Pssm-ID: 273126 [Multi-domain]  Cd Length: 367  Bit Score: 328.09  E-value: 2.91e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284   20 ASGIYTGDVYIVLGQTMLRINLHAFVLGSLIAVVVWYFLFKFIIGVFNIPEKMQRFGSARKGRKAALALNKAGLAYFEGR 99
Cdd:TIGR00540   1 ALAGNTGYVLIVYPPYRIELSLNFFVLLLVLLFVVLYILLRLIRRVFRLPRRVRAWRSRRKQRRAQQATREGLIALFEGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  100 FEKAEleaSRVLVNKEAGDNRTLALMLGAHAAGQMENIELRDRYLAEIAKLPEKQQLSRYLLLAESALNRRDYEAAEANL 179
Cdd:TIGR00540  81 YSQAE---KKATKAAEHSENPLLAYLLAARAAQQMGDEERRDRYLAEAAELAPNSELAVLLTRAELLLDQRDYEAALAAL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  180 HAAAKMNANLTRLVRLQLRYAFDRGDALQVLAKTEKLSKAGALGKSEMERYQNWAYRRQLADAAD--AAALKTCLKRIPD 257
Cdd:TIGR00540 158 DSLQAQAPRHTAVLRLALRAYQRSGNWDALLKLLPALRKAKALSPEEAARLEQQAYIGLLDEAREedADALKTWWKQLPR 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  258 SLK-NGELSVSVAEKYERLGLYADAVKWVKQHYPHNRRPELLEAFVESVRFLGEReqqkAIDFADAWLKEQPDNALLLMY 336
Cdd:TIGR00540 238 AERqEPELAVAAAEALIQLGDHDEAEKLIEEALKKEWDPELLRLYGRLQPGDPSP----LIKRAEKWLKKHPDDALLLLA 313

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 488155284  337 LGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAKVFDETGEPQKAEAQRNL 389
Cdd:TIGR00540 314 LGRLCLRQQLWGKAQSYLEASLSLAPTEEAHLELAQLFEQLGDTEAAAQHYRK 366
 
Name Accession Description Interval E-value
TPR_hemY_coli TIGR00540
heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized ...
 20-389 2.91e-110

heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General]


Pssm-ID: 273126 [Multi-domain]  Cd Length: 367  Bit Score: 328.09  E-value: 2.91e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284   20 ASGIYTGDVYIVLGQTMLRINLHAFVLGSLIAVVVWYFLFKFIIGVFNIPEKMQRFGSARKGRKAALALNKAGLAYFEGR 99
Cdd:TIGR00540   1 ALAGNTGYVLIVYPPYRIELSLNFFVLLLVLLFVVLYILLRLIRRVFRLPRRVRAWRSRRKQRRAQQATREGLIALFEGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  100 FEKAEleaSRVLVNKEAGDNRTLALMLGAHAAGQMENIELRDRYLAEIAKLPEKQQLSRYLLLAESALNRRDYEAAEANL 179
Cdd:TIGR00540  81 YSQAE---KKATKAAEHSENPLLAYLLAARAAQQMGDEERRDRYLAEAAELAPNSELAVLLTRAELLLDQRDYEAALAAL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  180 HAAAKMNANLTRLVRLQLRYAFDRGDALQVLAKTEKLSKAGALGKSEMERYQNWAYRRQLADAAD--AAALKTCLKRIPD 257
Cdd:TIGR00540 158 DSLQAQAPRHTAVLRLALRAYQRSGNWDALLKLLPALRKAKALSPEEAARLEQQAYIGLLDEAREedADALKTWWKQLPR 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  258 SLK-NGELSVSVAEKYERLGLYADAVKWVKQHYPHNRRPELLEAFVESVRFLGEReqqkAIDFADAWLKEQPDNALLLMY 336
Cdd:TIGR00540 238 AERqEPELAVAAAEALIQLGDHDEAEKLIEEALKKEWDPELLRLYGRLQPGDPSP----LIKRAEKWLKKHPDDALLLLA 313

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 488155284  337 LGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAKVFDETGEPQKAEAQRNL 389
Cdd:TIGR00540 314 LGRLCLRQQLWGKAQSYLEASLSLAPTEEAHLELAQLFEQLGDTEAAAQHYRK 366
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 84-396 1.87e-58

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 193.59  E-value: 1.87e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  84 AALALNKAGLAYFEGRFEKAELEASRVLvnkEAGDNRTLALMLGAHAAGQMENIELRDRYLAEIAKLPEKQQLSRYLLLA 163
Cdd:COG3071   16 LLAALLEGLLALAEGRYARAEKLLSKAA---EHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAELAVLLTRA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 164 ESALNRRDYEAAEANLHAAAKMNANLTRLVRLQLRYAFDRGDALQVLAKTEKLSKAGALGKSEMERYQNWAYRRQLADAA 243
Cdd:COG3071   93 ELLLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQALERRAYLGLLRQAA 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 244 D-AAALKTCLKRIPDSLK-NGELSVSVAEKYERLGLYADAVKWVKQHYPHNRRPELLEAFVEsvrfLGEREQQKAIDFAD 321
Cdd:COG3071  173 RdAEALKALWKALPRAERrDPELAAAYARALIALGDHDEAERLLREALKRQWDPRLVRLYGR----LQGGDPAKQLKRAE 248

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488155284 322 AWLKEQPDNALLLMYLGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAKVFDETGEPQKAEAQRNLVLASVAE 396
Cdd:COG3071  249 KWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
HemY_N pfam07219
HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of ...
 29-134 7.73e-16

HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of bacterial HemY porphyrin biosynthesis proteins. This is a membrane protein involved in a late step of protoheme IX synthesis.


Pssm-ID: 429353 [Multi-domain]  Cd Length: 104  Bit Score: 72.55  E-value: 7.73e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284   29 YIVLGQTMLRINLHAFVLGSLIAVVVWYFLFKFIIGVFNIPEKMQRFGSARKGRKAALALNKAGLAYFEGRFEKAELEAS 108
Cdd:pfam07219   1 LIVWGGYRIETSLWVAVLLLVLLFVLLYLLLRLLRLLLRLPGRVRRWRRRRRRRKARKALSEGLIALAEGDWAQAEKLAA 80

                          90       100
                  ....*....|....*....|....*.
gi 488155284  109 RVLvnkEAGDNRTLALMLGAHAAGQM 134
Cdd:pfam07219  81 KAA---KLLDAPLLNYLLAARAAQLQ 103
 
Name Accession Description Interval E-value
TPR_hemY_coli TIGR00540
heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized ...
 20-389 2.91e-110

heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General]


Pssm-ID: 273126 [Multi-domain]  Cd Length: 367  Bit Score: 328.09  E-value: 2.91e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284   20 ASGIYTGDVYIVLGQTMLRINLHAFVLGSLIAVVVWYFLFKFIIGVFNIPEKMQRFGSARKGRKAALALNKAGLAYFEGR 99
Cdd:TIGR00540   1 ALAGNTGYVLIVYPPYRIELSLNFFVLLLVLLFVVLYILLRLIRRVFRLPRRVRAWRSRRKQRRAQQATREGLIALFEGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  100 FEKAEleaSRVLVNKEAGDNRTLALMLGAHAAGQMENIELRDRYLAEIAKLPEKQQLSRYLLLAESALNRRDYEAAEANL 179
Cdd:TIGR00540  81 YSQAE---KKATKAAEHSENPLLAYLLAARAAQQMGDEERRDRYLAEAAELAPNSELAVLLTRAELLLDQRDYEAALAAL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  180 HAAAKMNANLTRLVRLQLRYAFDRGDALQVLAKTEKLSKAGALGKSEMERYQNWAYRRQLADAAD--AAALKTCLKRIPD 257
Cdd:TIGR00540 158 DSLQAQAPRHTAVLRLALRAYQRSGNWDALLKLLPALRKAKALSPEEAARLEQQAYIGLLDEAREedADALKTWWKQLPR 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  258 SLK-NGELSVSVAEKYERLGLYADAVKWVKQHYPHNRRPELLEAFVESVRFLGEReqqkAIDFADAWLKEQPDNALLLMY 336
Cdd:TIGR00540 238 AERqEPELAVAAAEALIQLGDHDEAEKLIEEALKKEWDPELLRLYGRLQPGDPSP----LIKRAEKWLKKHPDDALLLLA 313

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 488155284  337 LGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAKVFDETGEPQKAEAQRNL 389
Cdd:TIGR00540 314 LGRLCLRQQLWGKAQSYLEASLSLAPTEEAHLELAQLFEQLGDTEAAAQHYRK 366
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 84-396 1.87e-58

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 193.59  E-value: 1.87e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  84 AALALNKAGLAYFEGRFEKAELEASRVLvnkEAGDNRTLALMLGAHAAGQMENIELRDRYLAEIAKLPEKQQLSRYLLLA 163
Cdd:COG3071   16 LLAALLEGLLALAEGRYARAEKLLSKAA---EHSEAPLLAYLLAARAAQALGDYERRDEYLAQALELAPEAELAVLLTRA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 164 ESALNRRDYEAAEANLHAAAKMNANLTRLVRLQLRYAFDRGDALQVLAKTEKLSKAGALGKSEMERYQNWAYRRQLADAA 243
Cdd:COG3071   93 ELLLDQGQAEQALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELLPALRKHKALSAEEAQALERRAYLGLLRQAA 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 244 D-AAALKTCLKRIPDSLK-NGELSVSVAEKYERLGLYADAVKWVKQHYPHNRRPELLEAFVEsvrfLGEREQQKAIDFAD 321
Cdd:COG3071  173 RdAEALKALWKALPRAERrDPELAAAYARALIALGDHDEAERLLREALKRQWDPRLVRLYGR----LQGGDPAKQLKRAE 248

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488155284 322 AWLKEQPDNALLLMYLGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAKVFDETGEPQKAEAQRNLVLASVAE 396
Cdd:COG3071  249 KWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKALALALG 323
HemY_N pfam07219
HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of ...
 29-134 7.73e-16

HemY protein N-terminus; This family represents the N-terminus (approximately 150 residues) of bacterial HemY porphyrin biosynthesis proteins. This is a membrane protein involved in a late step of protoheme IX synthesis.


Pssm-ID: 429353 [Multi-domain]  Cd Length: 104  Bit Score: 72.55  E-value: 7.73e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284   29 YIVLGQTMLRINLHAFVLGSLIAVVVWYFLFKFIIGVFNIPEKMQRFGSARKGRKAALALNKAGLAYFEGRFEKAELEAS 108
Cdd:pfam07219   1 LIVWGGYRIETSLWVAVLLLVLLFVLLYLLLRLLRLLLRLPGRVRRWRRRRRRRKARKALSEGLIALAEGDWAQAEKLAA 80

                          90       100
                  ....*....|....*....|....*.
gi 488155284  109 RVLvnkEAGDNRTLALMLGAHAAGQM 134
Cdd:pfam07219  81 KAA---KLLDAPLLNYLLAARAAQLQ 103
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 312-386 3.09e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.14  E-value: 3.09e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488155284 312 EQQKAIDFADAWLKEQPDNALLLMYLGRLAYGRKLWGKAKGYLEASIALKPS-ISARLVLAKVFDETGEPQKAEAQ 386
Cdd:COG3914   93 RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDfAEAYLNLGEALRRLGRLEEAIAA 168
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 269-386 6.88e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.33  E-value: 6.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 269 AEKYERLGLYADAVKWVKQ---HYPHNRRPELLEAFVEsvrfLGEREQQKAIDFADAWLKEQPDNALLLMYLGRLAYGRK 345
Cdd:COG2956  151 AELYLEQGDYDEAIEALEKalkLDPDCARALLLLAELY----LEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLG 226

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 488155284 346 LWGKAKGYLEASIALKPSISARLVLAKVFDETGEPQKAEAQ 386
Cdd:COG2956  227 DPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALAL 267
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 295-399 2.60e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 2.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  295 PELLEA-FVESVRFLGEREQQKAIDFADAWLKEQPDNALLLMYLGRLAYGRKLWGKAKGYLEASIALKP-SISARLVLAK 372
Cdd:TIGR02917 428 PELGRAdLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPdFFPAAANLAR 507

                          90       100
                  ....*....|....*....|....*..
gi 488155284  373 VFDETGEPQKAEAQRNLVLASVAEENR 399
Cdd:TIGR02917 508 IDIQEGNPDDAIQRFEKVLTIDPKNLR 534
HemYx COG3898
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type ...
 2-396 1.62e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type protoporphyrinogen oxidase) [Function unknown];


Pssm-ID: 443105 [Multi-domain]  Cd Length: 468  Bit Score: 40.65  E-value: 1.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284   2 KTVVWIVVLFAAAVGLALASGiYTGDVYIVLGQTMLRINLHAFVLGSLIAVVVWYFLFKFIIGVFNIPEKMQRFGSARKG 81
Cdd:COG3898    3 RILLFLALVAALALGAAWLAD-RPGTVSITWLGYEIETSLLVAAIALLVLAAAVWLLWRLLRFLLGSPTALSRYFRRRRR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284  82 RKAALALNKAGLAYFEGRFE---KAELEASRVLvnkeagDNRTLALMLGAHAAgQME-NIELRDRYLAEIAKLPEKQQLS 157
Cdd:COG3898   82 RKGYQALSRGLIAVAAGDGRlarRKAAKAERLL------DRPPLTLLLEAQAA-QLAgDREAARRAFEAMLEDPETRFLG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 158 RYLLLAEsALNRRDYEAAEANLHAAAKMNANLTRLVRLQLRYAFDRGD---ALQVLaktEKLSKAGALGKSEMERYQN-- 232
Cdd:COG3898  155 LRGLMVE-ALRRGDTEAALALAEEALALAPKLPWAQDALLELQAAAGDwdgALATL---DAALKAGLLDKDVARRRRAvl 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 233 -WAYRRQLADAADAAALKT---CLKRIPDSLkngELSVSVAEKYERLGLYADAVK-----WVKQhyPHnrrPELLEAFVE 303
Cdd:COG3898  231 lTARARELEEGDPDEARELaieALKLAPDLV---PAAVLAARLLIAQGKLRKAAKvlekaWRAQ--PH---PDLAAAYAE 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 304 SvrflgeREQQKAIDF---ADAWLKEQPDNALLLMYLGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAKVfdETGEP 380
Cdd:COG3898  303 L------RPGDSALDRlkrAETLAALNPDHPESRLALAEAALAAGDFGEARRALGPLLEERPTARVCLLMAEI--ERGEH 374

                        410
                 ....*....|....*..
gi 488155284 381 Q-KAEAQRNLVLASVAE 396
Cdd:COG3898  375 GdDGRVREWLARALRAP 391
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 269-386 3.45e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 3.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 269 AEKYERLGLYADAVKWVKQ---HYPHNrrPELLEAFVESVRFLGEREQqkAIDFADAWLKEQPDNALLLMYLGRLAYGRK 345
Cdd:COG4783   11 AQALLLAGDYDEAEALLEKaleLDPDN--PEAFALLGEILLQLGDLDE--AIVLLHEALELDPDEPEARLNLGLALLKAG 86

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 488155284 346 LWGKAKGYLEASIALKP-SISARLVLAKVFDETGEPQKAEAQ 386
Cdd:COG4783   87 DYDEALALLEKALKLDPeHPEAYLRLARAYRALGRPDEAIAA 128
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 219-385 4.26e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 39.21  E-value: 4.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 219 AGALGKSEMERYQNWAYRRQLADAADAAALKTCLKRIPDSLkngelsvsvAEKYERLGLYADAVkwvkQHYPH--NRRPE 296
Cdd:COG3914   44 ALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELA---------ALLLQALGRYEEAL----ALYRRalALNPD 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 297 LLEAFVESVRFLGEREQ-QKAIDFADAWLKEQPDNALLLMYLGRLAYGRKLWGKAKGYLEASIALKPS-ISARLVLAKVF 374
Cdd:COG3914  111 NAEALFNLGNLLLALGRlEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDnAEALNNLGNAL 190

                        170
                 ....*....|.
gi 488155284 375 DETGEPQKAEA 385
Cdd:COG3914  191 QDLGRLEEAIA 201
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 248-372 6.42e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.52  E-value: 6.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488155284 248 LKTCLKRIPDslkNGELSVSVAEKYERLGLYADAVKWVKQHYPHN-RRPELLEAFVESVRFLGEreQQKAIDFADAWLKE 326
Cdd:COG4235    6 LRQALAANPN---DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDpDNADALLDLAEALLAAGD--TEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 488155284 327 QPDNALLLMYLGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAK 372
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEA 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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