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Conserved domains on  [gi|488157193|ref|WP_002228401|]
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MULTISPECIES: DnaA inactivator Hda [Yersinia pseudotuberculosis complex]

Protein Classification

DnaA inactivator Hda( domain architecture ID 10012996)

DnaA inactivator Hda mediates the interactions of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK08084 PRK08084
DnaA inactivator Hda;
1-235 0e+00

DnaA inactivator Hda;


:

Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 505.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   1 MLLNTPAQLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVP 80
Cdd:PRK08084   1 VSLNTPAQLSLPLYLPDDETFASFYPGDNDSLLAALQNALRQEHSGYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  81 LDKRAYFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRTRLLITGDRPPRQLNLGLPDLASRLDWGQ 160
Cdd:PRK08084  81 LDKRAWFVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRTRLLITGDRPPRQLNLGLPDLASRLDWGQ 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488157193 161 IYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILSL 235
Cdd:PRK08084 161 IYKLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL 235
 
Name Accession Description Interval E-value
PRK08084 PRK08084
DnaA inactivator Hda;
1-235 0e+00

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 505.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   1 MLLNTPAQLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVP 80
Cdd:PRK08084   1 VSLNTPAQLSLPLYLPDDETFASFYPGDNDSLLAALQNALRQEHSGYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  81 LDKRAYFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRTRLLITGDRPPRQLNLGLPDLASRLDWGQ 160
Cdd:PRK08084  81 LDKRAWFVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRTRLLITGDRPPRQLNLGLPDLASRLDWGQ 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488157193 161 IYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILSL 235
Cdd:PRK08084 161 IYKLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL 235
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 8-233 7.96e-102

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 294.48  E-value: 7.96e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193    8 QLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVPLDKRAYF 87
Cdd:TIGR03420   1 QLPLDVGLPDDPTFDNFYAGGNAELLAALRQLAAGKGDRFLYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAELAQA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   88 IPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPL 167
Cdd:TIGR03420  81 DPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGG-RLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLPPL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488157193  168 SDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEIL 233
Cdd:TIGR03420 160 SDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVL 225
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
20-234 1.24e-50

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 166.91  E-value: 1.24e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  20 TFASFYPGE-NPSLLAAIQSAVHQPHGSY--IYFWSREGGGRSHLLHAACAELSQQ--GEAVGYVPLDK---------RA 85
Cdd:COG0593    6 TFDNFVVGPsNRLAHAAALAVAEWPGKAYnpLFLYGGVGLGKTHLLHAIGNEALENnpGARVVYLTAEEftndfinaiRN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  86 YFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQ 165
Cdd:COG0593   86 NTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGK-QIVLTSDRPPKELPGLEERLRSRLEWGLVVDIQ 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488157193 166 PLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILS 234
Cdd:COG0593  165 PPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLK 233
Bac_DnaA pfam00308
Bacterial dnaA protein;
20-206 2.15e-20

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 85.84  E-value: 2.15e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   20 TFASFYPGENPSL-LAAIQSAVHQPHGSY--IYFWSREGGGRSHLLHAAC--AELSQQGEAVGYVPLDkraYFIPEVLEG 94
Cdd:pfam00308   6 TFENFVIGPSNRFaHAAALTVAKAPGKAYnpLFIYGGVGLGKTHLLHAIGnyALQNAPNLRVVYLTAE---EFLNDFVDA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   95 ME------------QLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNlGLPD-LASRLDWGQI 161
Cdd:pfam00308  83 IRdnktnqfkekyrNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGK-QIVFSSDRPPKELE-ELEDrLRSRFQWGLV 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 488157193  162 YKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTL 206
Cdd:pfam00308 161 TDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVREL 205
 
Name Accession Description Interval E-value
PRK08084 PRK08084
DnaA inactivator Hda;
1-235 0e+00

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 505.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   1 MLLNTPAQLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVP 80
Cdd:PRK08084   1 VSLNTPAQLSLPLYLPDDETFASFYPGDNDSLLAALQNALRQEHSGYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  81 LDKRAYFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRTRLLITGDRPPRQLNLGLPDLASRLDWGQ 160
Cdd:PRK08084  81 LDKRAWFVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRTRLLITGDRPPRQLNLGLPDLASRLDWGQ 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488157193 161 IYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILSL 235
Cdd:PRK08084 161 IYKLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL 235
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 8-233 7.96e-102

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 294.48  E-value: 7.96e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193    8 QLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVPLDKRAYF 87
Cdd:TIGR03420   1 QLPLDVGLPDDPTFDNFYAGGNAELLAALRQLAAGKGDRFLYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAELAQA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   88 IPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPL 167
Cdd:TIGR03420  81 DPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGG-RLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLPPL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488157193  168 SDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEIL 233
Cdd:TIGR03420 160 SDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVL 225
PRK08903 PRK08903
DnaA regulatory inactivator Hda; Validated
 5-233 1.21e-55

DnaA regulatory inactivator Hda; Validated


Pssm-ID: 236347 [Multi-domain]  Cd Length: 227  Bit Score: 177.48  E-value: 1.21e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   5 TPAQLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQP-HGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVPLDK 83
Cdd:PRK08903   1 MMRQLTLDLGPPPPPTFDNFVAGENAELVARLRELAAGPvADRFFYLWGEAGSGRSHLLQALVADASYGGRNARYLDAAS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  84 RayfiPEVLEGMEQLALVCIDNIECIAGDEQweMAMFNLYNRIVETGRTRLLITGDRPPRQLNLgLPDLASRLDWGQIYK 163
Cdd:PRK08903  81 P----LLAFDFDPEAELYAVDDVERLDDAQQ--IALFNLFNRVRAHGQGALLVAGPAAPLALPL-REDLRTRLGWGLVYE 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193 164 LQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEIL 233
Cdd:PRK08903 154 LKPLSDADKIAALKAAAAERGLQLADEVPDYLLTHFRRDMPSLMALLDALDRYSLEQKRPVTLPLLREML 223
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
20-234 1.24e-50

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 166.91  E-value: 1.24e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  20 TFASFYPGE-NPSLLAAIQSAVHQPHGSY--IYFWSREGGGRSHLLHAACAELSQQ--GEAVGYVPLDK---------RA 85
Cdd:COG0593    6 TFDNFVVGPsNRLAHAAALAVAEWPGKAYnpLFLYGGVGLGKTHLLHAIGNEALENnpGARVVYLTAEEftndfinaiRN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  86 YFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQ 165
Cdd:COG0593   86 NTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGK-QIVLTSDRPPKELPGLEERLRSRLEWGLVVDIQ 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488157193 166 PLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILS 234
Cdd:COG0593  165 PPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLK 233
Bac_DnaA pfam00308
Bacterial dnaA protein;
20-206 2.15e-20

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 85.84  E-value: 2.15e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   20 TFASFYPGENPSL-LAAIQSAVHQPHGSY--IYFWSREGGGRSHLLHAAC--AELSQQGEAVGYVPLDkraYFIPEVLEG 94
Cdd:pfam00308   6 TFENFVIGPSNRFaHAAALTVAKAPGKAYnpLFIYGGVGLGKTHLLHAIGnyALQNAPNLRVVYLTAE---EFLNDFVDA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   95 ME------------QLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNlGLPD-LASRLDWGQI 161
Cdd:pfam00308  83 IRdnktnqfkekyrNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGK-QIVFSSDRPPKELE-ELEDrLRSRFQWGLV 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 488157193  162 YKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTL 206
Cdd:pfam00308 161 TDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVREL 205
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 20-234 9.83e-17

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 78.34  E-value: 9.83e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   20 TFASFYPGENPSL-LAAIQSAVHQPHGSY----IYfwsreGG---GRSHLLHAACAE-LSQQGEA-VGYVPLDKrayFIP 89
Cdd:TIGR00362 109 TFDNFVVGKSNRLaHAAALAVAENPGKAYnplfIY-----GGvglGKTHLLHAIGNEiLENNPNAkVLYVSSEK---FTN 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193   90 EVLEGM------------EQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNlGLPD-LASRL 156
Cdd:TIGR00362 181 DFVNALrnnkmeefkekyRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHENNK-QIVLTSDRPPKELP-GLEDrLRSRF 258

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488157193  157 DWGQIYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLD-RASITaQRKLTIPFVKEILS 234
Cdd:TIGR00362 259 EWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNVRELEGALNRLLaYASLT-GKPITLELAKEALK 336
dnaA PRK00149
chromosomal replication initiator protein DnaA;
20-234 4.36e-16

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 76.33  E-value: 4.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  20 TFASFYPGENPSL-LAAIQSAVHQPHGSY--IYFWSREGGGRSHLLHAACAE-LSQQGEA-VGYVPLDKrayFIPEVLE- 93
Cdd:PRK00149  71 TFDNFVVGKSNRLaHAAALAVAENPGKAYnpLFIYGGVGLGKTHLLHAIGNYiLEKNPNAkVVYVTSEK---FTNDFVNa 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  94 ----GMEQL--------ALVcIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNlGLPD-LASRLDWGQ 160
Cdd:PRK00149 148 lrnnTMEEFkekyrsvdVLL-IDDIQFLAGKERTQEEFFHTFNALHEAGK-QIVLTSDRPPKELP-GLEErLRSRFEWGL 224

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488157193 161 IYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTL---FMTLdqLDRASITaQRKLTIPFVKEILS 234
Cdd:PRK00149 225 TVDIEPPDLETRIAILKKKAEEEGIDLPDEVLEFIAKNITSNVRELegaLNRL--IAYASLT-GKPITLELAKEALK 298
PRK06620 PRK06620
hypothetical protein; Validated
 85-234 6.35e-13

hypothetical protein; Validated


Pssm-ID: 168630  Cd Length: 214  Bit Score: 65.63  E-value: 6.35e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  85 AYFIPEVL---EGMEQLALVCIDNIEciagdeQW-EMAMFNLYNRIVETGRTRLLITGDRPPrqlNLGLPDLASRLDWGQ 160
Cdd:PRK06620  70 AYIIKDIFfneEILEKYNAFIIEDIE------NWqEPALLHIFNIINEKQKYLLLTSSDKSR---NFTLPDLSSRIKSVL 140

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488157193 161 IYKLQPlSDDEKLQALQLRA-KLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILS 234
Cdd:PRK06620 141 SILLNS-PDDELIKILIFKHfSISSVTISRQIIDFLLVNLPREYSKIIEILENINYFALISKRKITISLVKEVLN 214
dnaA PRK14086
chromosomal replication initiator protein DnaA;
20-206 3.77e-11

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 62.15  E-value: 3.77e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  20 TFASFYPG-ENPSLLAAIQSAVHQPHGSY--IYFWSREGGGRSHLLHAA--CAELSQQGEAVGYVPLDK-RAYFIPEVLE 93
Cdd:PRK14086 286 TFDTFVIGaSNRFAHAAAVAVAEAPAKAYnpLFIYGESGLGKTHLLHAIghYARRLYPGTRVRYVSSEEfTNEFINSIRD 365

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  94 G--------MEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLnLGLPD-LASRLDWGQIYKL 164
Cdd:PRK14086 366 GkgdsfrrrYREMDILLVDDIQFLEDKESTQEEFFHTFNTLHNANK-QIVLSSDRPPKQL-VTLEDrLRNRFEWGLITDV 443

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 488157193 165 QPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTL 206
Cdd:PRK14086 444 QPPELETRIAILRKKAVQEQLNAPPEVLEFIASRISRNIREL 485
PRK12422 PRK12422
chromosomal replication initiator protein DnaA;
20-213 1.41e-10

chromosomal replication initiator protein DnaA;


Pssm-ID: 183521 [Multi-domain]  Cd Length: 445  Bit Score: 60.23  E-value: 1.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  20 TFASFYPGENPSL----LAAIQSAVHQPHG---SYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVPLDK-RAYFIPEV 91
Cdd:PRK12422 109 TFANFLVTPENDLphriLQEFTKVSEQGKGfpfNPIYLFGPEGSGKTHLMQAAVHALRESGGKILYVRSELfTEHLVSAI 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193  92 LEGMEQL---------ALVcIDNIECIAGDEQWEMAMFNLYNRIVETGRtRLLITGDRPPRQLNLGLPDLASRLDWGQIY 162
Cdd:PRK12422 189 RSGEMQRfrqfyrnvdALF-IEDIEVFSGKGATQEEFFHTFNSLHTEGK-LIVISSTCAPQDLKAMEERLISRFEWGIAI 266

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 488157193 163 KLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQL 213
Cdd:PRK12422 267 PLHPLTKEGLRSFLERKAEALSIRIEETALDFLIEALSSNVKSLLHALTLL 317
PRK09087 PRK09087
hypothetical protein; Validated
 101-234 6.40e-10

hypothetical protein; Validated


Pssm-ID: 169652 [Multi-domain]  Cd Length: 226  Bit Score: 57.38  E-value: 6.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488157193 101 VCIDNIECIAGDEQwemAMFNLYNRIVETGrTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKL-QPlsDDEKLQalQLR 179
Cdd:PRK09087  91 VLIEDIDAGGFDET---GLFHLINSVRQAG-TSLLMTSRLWPSSWNVKLPDLKSRLKAATVVEIgEP--DDALLS--QVI 162

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488157193 180 AKL---RGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILS 234
Cdd:PRK09087 163 FKLfadRQLYVDPHVVYYLVSRMERSLFAAQTIVDRLDRLALERKSRITRALAAEVLN 220
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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