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Conserved domains on  [gi|488217190|ref|WP_002288398|]
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MULTISPECIES: YozE family protein [Enterococcus]

Protein Classification

YozE family protein; YozE family protein; sterile alpha motif-like domain-containing protein; YozE family protein; sterile alpha motif-like domain-containing protein; YozE family protein; sterile alpha motif-like domain-containing protein( domain architecture ID 10008589)

sterile alpha motif-like domain-containing protein adopts a four-helix motif, similar to MW0776 and MW1311 from Staphyloccocus aureus and yozE from Bacillus subtilis; uncharacterized protein similar to Bacillus subtilis YozE, containing a four-helix motif that is similar to the sterile alpha motif (SAM) domain; sterile alpha motif-like domain-containing protein adopts a four-helix motif, similar to MW0776 and MW1311 from Staphyloccocus aureus and yozE from Bacillus subtilis; uncharacterized protein similar to Bacillus subtilis YozE, containing a four-helix motif that is similar to the sterile alpha motif (SAM) domain; sterile alpha motif-like domain-containing protein adopts a four-helix motif, similar to MW0776 and MW1311 from Staphyloccocus aureus and yozE from Bacillus subtilis; uncharacterized protein similar to Bacillus subtilis YozE, containing a four-helix motif that is similar to the sterile alpha motif (SAM) domain; uncharacterized protein similar to Bacillus subtilis YozE, containing a four-helix motif that is similar to the sterile alpha motif (SAM) domain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YozE COG4479
Uncharacterized conserved protein YozE, UPF0346 family [Function unknown];
2-71 9.12e-33

Uncharacterized conserved protein YozE, UPF0346 family [Function unknown];


:

Pssm-ID: 443576  Cd Length: 70  Bit Score: 107.29  E-value: 9.12e-33
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488217190  2 NRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEISNYLELNVDYLPSMDIFDEAWEKYLEN 71
Cdd:COG4479   1 RRSFYQYLMTYRGPKKKDPKSDFANDAFLDHSFPKQSDDYDELSDYLELNGDYLGALSVFDELWEEYLER 70
 
Name Accession Description Interval E-value
YozE COG4479
Uncharacterized conserved protein YozE, UPF0346 family [Function unknown];
2-71 9.12e-33

Uncharacterized conserved protein YozE, UPF0346 family [Function unknown];


Pssm-ID: 443576  Cd Length: 70  Bit Score: 107.29  E-value: 9.12e-33
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488217190  2 NRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEISNYLELNVDYLPSMDIFDEAWEKYLEN 71
Cdd:COG4479   1 RRSFYQYLMTYRGPKKKDPKSDFANDAFLDHSFPKQSDDYDELSDYLELNGDYLGALSVFDELWEEYLER 70
PRK13672 PRK13672
hypothetical protein; Provisional
 1-71 1.63e-31

hypothetical protein; Provisional


Pssm-ID: 184229  Cd Length: 71  Bit Score: 104.18  E-value: 1.63e-31
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488217190  1 MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEISNYLELNVDYLPSMDIFDEAWEKYLEN 71
Cdd:PRK13672  1 MRKSFYHYLMTQRNPKSNDPKAILANNAFDDLSFPKQSDDFDELSRYLELNASYLFSMSIFDEAWEEYLEH 71
YozE_SAM_like pfam06855
YozE SAM-like fold; YozE-like is a family of Firmicute proteins that carries a four-helix ...
 5-70 5.26e-25

YozE SAM-like fold; YozE-like is a family of Firmicute proteins that carries a four-helix motif similar to sterile alpha motif (SAM) domains. The family is suggested to fall into two subfamilies, possibly with differing functions based on the different surface charges on the three structural representatives, YozE MW0776 and MW1311. What this function is is not yet known although it is likely to involve binding to DNA.


Pssm-ID: 429156  Cd Length: 65  Bit Score: 87.65  E-value: 5.26e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488217190   5 FFHYLMTLRGGgTHDALSVFATEAGKDIQFPKHSSSYEEISNYLELNVDYLPSMDIFDEAWEKYLE 70
Cdd:pfam06855  1 FYQFLMTFRGP-DNDPVGDFANNAFKDHSFPKQSTDYDEISDYLELNGPYLSSMEIFDEAWDLYLE 65
 
Name Accession Description Interval E-value
YozE COG4479
Uncharacterized conserved protein YozE, UPF0346 family [Function unknown];
2-71 9.12e-33

Uncharacterized conserved protein YozE, UPF0346 family [Function unknown];


Pssm-ID: 443576  Cd Length: 70  Bit Score: 107.29  E-value: 9.12e-33
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488217190  2 NRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEISNYLELNVDYLPSMDIFDEAWEKYLEN 71
Cdd:COG4479   1 RRSFYQYLMTYRGPKKKDPKSDFANDAFLDHSFPKQSDDYDELSDYLELNGDYLGALSVFDELWEEYLER 70
PRK13672 PRK13672
hypothetical protein; Provisional
 1-71 1.63e-31

hypothetical protein; Provisional


Pssm-ID: 184229  Cd Length: 71  Bit Score: 104.18  E-value: 1.63e-31
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488217190  1 MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEISNYLELNVDYLPSMDIFDEAWEKYLEN 71
Cdd:PRK13672  1 MRKSFYHYLMTQRNPKSNDPKAILANNAFDDLSFPKQSDDFDELSRYLELNASYLFSMSIFDEAWEEYLEH 71
YozE_SAM_like pfam06855
YozE SAM-like fold; YozE-like is a family of Firmicute proteins that carries a four-helix ...
 5-70 5.26e-25

YozE SAM-like fold; YozE-like is a family of Firmicute proteins that carries a four-helix motif similar to sterile alpha motif (SAM) domains. The family is suggested to fall into two subfamilies, possibly with differing functions based on the different surface charges on the three structural representatives, YozE MW0776 and MW1311. What this function is is not yet known although it is likely to involve binding to DNA.


Pssm-ID: 429156  Cd Length: 65  Bit Score: 87.65  E-value: 5.26e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488217190   5 FFHYLMTLRGGgTHDALSVFATEAGKDIQFPKHSSSYEEISNYLELNVDYLPSMDIFDEAWEKYLE 70
Cdd:pfam06855  1 FYQFLMTFRGP-DNDPVGDFANNAFKDHSFPKQSTDYDEISDYLELNGPYLSSMEIFDEAWDLYLE 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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