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Conserved domains on  [gi|488224005|ref|WP_002295213|]
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MULTISPECIES: shikimate kinase [Enterococcus]

Protein Classification

shikimate kinase( domain architecture ID 11431165)

shikimate kinase catalyzes the specific phosphorylation of the 3-hydroxylgroup of shikimic acid using ATP as a cosubstrate

CATH:  3.40.50.300
EC:  2.7.1.71
Gene Ontology:  GO:0009073|GO:0004765|GO:0000287|GO:0005524|GO:0008652
PubMed:  2279393|7870841
SCOP:  4003925

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 4-168 2.42e-62

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


:

Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 189.57  E-value: 2.42e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSN-EDKIIATGGGIVQ 82
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEeENAVIATGGGAVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  83 SAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGK-TREEIKALLAQRLSWYEESATHRINTTNQTPEKIIDT 161
Cdd:COG0703   81 SPENRELLKEHGTVVYLDASPETLLERLRRDDN--RPLLQGEdPRERLEELLAEREPLYREVADITVDTDGRSPEEVVDE 158


                 ....*..
gi 488224005 162 IIERIKS 168
Cdd:COG0703  159 ILEALEE 165
 
Name Accession Description Interval E-value
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 4-168 2.42e-62

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 189.57  E-value: 2.42e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSN-EDKIIATGGGIVQ 82
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEeENAVIATGGGAVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  83 SAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGK-TREEIKALLAQRLSWYEESATHRINTTNQTPEKIIDT 161
Cdd:COG0703   81 SPENRELLKEHGTVVYLDASPETLLERLRRDDN--RPLLQGEdPRERLEELLAEREPLYREVADITVDTDGRSPEEVVDE 158


                 ....*..
gi 488224005 162 IIERIKS 168
Cdd:COG0703  159 ILEALEE 165
aroK PRK00131
shikimate kinase; Reviewed
 1-168 3.45e-62

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 189.63  E-value: 3.45e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   1 MASILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNEDK-IIATGGG 79
Cdd:PRK00131   4 GPNIVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLARHNlVISTGGG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  80 IVQSAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLAL-GKTREEIKALLAQRLSWYEESATHRINTTNQTPEKI 158
Cdd:PRK00131  84 AVLREENRALLRERGTVVYLDASFEELLRRLRRDRN--RPLLQtNDPKEKLRDLYEERDPLYEEVADITVETDGRSPEEV 161

                        170
                 ....*....|
gi 488224005 159 IDTIIERIKS 168
Cdd:PRK00131 162 VNEILEKLEA 171
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 3-156 1.05e-55

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 172.35  E-value: 1.05e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   3 SILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLS-NEDKIIATGGGIV 81
Cdd:cd00464    1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEREVLLLLLtKENAVIATGGGAV 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488224005  82 QSAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPE 156
Cdd:cd00464   81 LREENRRLLLENGIVVWLDASPEELLERLARDKT--RPLLQDEDPERLRELLEEREPLYREVADLTIDTDELSPE 153
SKI pfam01202
Shikimate kinase;
10-167 2.02e-50

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 158.90  E-value: 2.02e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   10 MGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNE-DKIIATGGGIVQSAENRR 88
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAEhGLVIATGGGAVLSEENRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   89 FLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGKTREE--IKALLAQRLSWYEESATHRINTTNQTPEKIIDTIIERI 166
Cdd:pfam01202  81 LLKERGIVIYLDAPLEVLLERLKRDKT--RPLLQNKDPEEelLELLFEERDPLYEEAADIVIDTDESSPEEVATEILEAL 158


                  .
gi 488224005  167 K 167
Cdd:pfam01202 159 E 159
 
Name Accession Description Interval E-value
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 4-168 2.42e-62

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 189.57  E-value: 2.42e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSN-EDKIIATGGGIVQ 82
Cdd:COG0703    1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEeENAVIATGGGAVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  83 SAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGK-TREEIKALLAQRLSWYEESATHRINTTNQTPEKIIDT 161
Cdd:COG0703   81 SPENRELLKEHGTVVYLDASPETLLERLRRDDN--RPLLQGEdPRERLEELLAEREPLYREVADITVDTDGRSPEEVVDE 158


                 ....*..
gi 488224005 162 IIERIKS 168
Cdd:COG0703  159 ILEALEE 165
aroK PRK00131
shikimate kinase; Reviewed
 1-168 3.45e-62

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 189.63  E-value: 3.45e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   1 MASILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNEDK-IIATGGG 79
Cdd:PRK00131   4 GPNIVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLARHNlVISTGGG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  80 IVQSAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLAL-GKTREEIKALLAQRLSWYEESATHRINTTNQTPEKI 158
Cdd:PRK00131  84 AVLREENRALLRERGTVVYLDASFEELLRRLRRDRN--RPLLQtNDPKEKLRDLYEERDPLYEEVADITVETDGRSPEEV 161

                        170
                 ....*....|
gi 488224005 159 IDTIIERIKS 168
Cdd:PRK00131 162 VNEILEKLEA 171
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 3-156 1.05e-55

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 172.35  E-value: 1.05e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   3 SILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLS-NEDKIIATGGGIV 81
Cdd:cd00464    1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEREVLLLLLtKENAVIATGGGAV 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488224005  82 QSAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPE 156
Cdd:cd00464   81 LREENRRLLLENGIVVWLDASPEELLERLARDKT--RPLLQDEDPERLRELLEEREPLYREVADLTIDTDELSPE 153
SKI pfam01202
Shikimate kinase;
10-167 2.02e-50

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 158.90  E-value: 2.02e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   10 MGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNE-DKIIATGGGIVQSAENRR 88
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAEhGLVIATGGGAVLSEENRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   89 FLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGKTREE--IKALLAQRLSWYEESATHRINTTNQTPEKIIDTIIERI 166
Cdd:pfam01202  81 LLKERGIVIYLDAPLEVLLERLKRDKT--RPLLQNKDPEEelLELLFEERDPLYEEAADIVIDTDESSPEEVATEILEAL 158


                  .
gi 488224005  167 K 167
Cdd:pfam01202 159 E 159
aroL PRK03731
shikimate kinase AroL;
4-168 2.33e-42

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 138.92  E-value: 2.33e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQS 83
Cdd:PRK03731   5 LFLVGARGCGKTTVGMALAQALGYRFVDTDQWLQSTSNMTVAEIVEREGWAGFRARESAALEAVTAPSTVIATGGGIILT 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  84 AENRRFLKTQPIVLYLEAEADCLVDRIQQD-ETSIRPLALGKT-REEIKALLAQRLSWYEESATHRINTTnQTPEKIIDT 161
Cdd:PRK03731  85 EENRHFMRNNGIVIYLCAPVSVLANRLEANpEEDQRPTLTGKPiSEEVAEVLAEREALYREVAHHIIDAT-QPPSQVVSE 163


                 ....*..
gi 488224005 162 IIERIKS 168
Cdd:PRK03731 164 ILSALAQ 170
PRK13947 PRK13947
shikimate kinase; Provisional
 1-164 5.32e-36

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 122.89  E-value: 5.32e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   1 MASILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNEDK-IIATGGG 79
Cdd:PRK13947   1 MKNIVLIGFMGTGKTTVGKRVATTLSFGFIDTDKEIEKMTGMTVAEIFEKDGEVRFRSEEKLLVKKLARLKNlVIATGGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  80 IVQSAENRRFLKTQPIVLYLEAEADCLVDRIQQdeTSIRP-LALGKTREEIKALLAQRLSWYeESATHRINTTNQTPEKI 158
Cdd:PRK13947  81 VVLNPENVVQLRKNGVVICLKARPEVILRRVGK--KKSRPlLMVGDPEERIKELLKEREPFY-DFADYTIDTGDMTIDEV 157


                 ....*.
gi 488224005 159 IDTIIE 164
Cdd:PRK13947 158 AEEIIK 163
aroK PRK05057
shikimate kinase AroK;
4-166 5.57e-34

shikimate kinase AroK;


Pssm-ID: 235335 [Multi-domain]  Cd Length: 172  Bit Score: 117.51  E-value: 5.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNEDKII-ATGGGIVQ 82
Cdd:PRK05057   7 IFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADIGWVFDVEGEEGFRDREEKVINELTEKQGIVlATGGGSVK 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  83 SAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGKT-REEIKALLAQRLSWYEESATHRINTTNQTPEKIIDT 161
Cdd:PRK05057  87 SRETRNRLSARGVVVYLETTIEKQLARTQRDKK--RPLLQVDDpREVLEALANERNPLYEEIADVTIRTDDQSAKVVANQ 164


                 ....*
gi 488224005 162 IIERI 166
Cdd:PRK05057 165 IIHML 169
PRK13946 PRK13946
shikimate kinase; Provisional
 3-166 1.26e-33

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 116.95  E-value: 1.26e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   3 SILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESD-ILRKLSNEDKIIATGGGIV 81
Cdd:PRK13946  12 TVVLVGLMGAGKSTVGRRLATMLGLPFLDADTEIERAARMTIAEIFAAYGEPEFRDLERRvIARLLKGGPLVLATGGGAF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  82 QSAENRRFLKTQPIVLYLEAEADCLVDRIQQDETsiRPLALGKT-REEIKALLAQRLSWYEESATHrINTTNQTPEKIID 160
Cdd:PRK13946  92 MNEETRAAIAEKGISVWLKADLDVLWERVSRRDT--RPLLRTADpKETLARLMEERYPVYAEADLT-VASRDVPKEVMAD 168


                 ....*.
gi 488224005 161 TIIERI 166
Cdd:PRK13946 169 EVIEAL 174
PRK13948 PRK13948
shikimate kinase; Provisional
 6-166 6.97e-28

shikimate kinase; Provisional


Pssm-ID: 184413 [Multi-domain]  Cd Length: 182  Bit Score: 102.17  E-value: 6.97e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   6 LIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNEDK-IIATGGGIVQSA 84
Cdd:PRK13948  15 LAGFMGTGKSRIGWELSRALMLHFIDTDRYIERVTGKSIPEIFRHLGEAYFRRCEAEVVRRLTRLDYaVISLGGGTFMHE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  85 ENRRFLKTQPIVLYLEAEADCLVDRIQQDEtsiRP-LALGKTREEIKALLAQRLSWYEESATHrINTTNQTPEKIIDTII 163
Cdd:PRK13948  95 ENRRKLLSRGPVVVLWASPETIYERTRPGD---RPlLQVEDPLGRIRTLLNEREPVYRQATIH-VSTDGRRSEEVVEEIV 170


                 ...
gi 488224005 164 ERI 166
Cdd:PRK13948 171 EKL 173
PRK13949 PRK13949
shikimate kinase; Provisional
 1-166 2.40e-27

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 100.57  E-value: 2.40e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   1 MASILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSN-EDKIIATGGG 79
Cdd:PRK13949   1 MARIFLVGYMGAGKTTLGKALARELGLSFIDLDFFIENRFHKTVGDIFAERGEAVFRELERNMLHEVAEfEDVVISTGGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  80 IVQSAENRRFLKTQPIVLYLEAEADCLVDRIQQDETSiRPLALGKTREEIKALLAQRLSWYE---ESATHRINTTNQTPE 156
Cdd:PRK13949  81 APCFFDNMELMNASGTTVYLKVSPEVLFVRLRLAKQQ-RPLLKGKSDEELLDFIIEALEKRApfyRQAKIIFNADKLEDE 159

                        170
                 ....*....|
gi 488224005 157 KIIDTIIERI 166
Cdd:PRK13949 160 SQIEQLVQRL 169
PRK13951 PRK13951
bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;
4-154 1.23e-25

bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;


Pssm-ID: 172457 [Multi-domain]  Cd Length: 488  Bit Score: 101.52  E-value: 1.23e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKLSNEDK-IIATGGGIVQ 82
Cdd:PRK13951   3 IFLVGMMGSGKSTIGKRVSEVLDLQFIDMDEEIERREGRSVRRIFEEDGEEYFRLKEKELLRELVERDNvVVATGGGVVI 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488224005  83 SAENRRFLKTQPiVLYLEAEADCLVDRIQqdeTSIRPLaLGKTREEIKALLAQRLSWYEESAThrINTTNQT 154
Cdd:PRK13951  83 DPENRELLKKEK-TLFLYAPPEVLMERVT---TENRPL-LREGKERIREIWERRKQFYTEFRG--IDTSKLN 147
PRK14021 PRK14021
bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional
 5-166 5.84e-25

bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional


Pssm-ID: 184458 [Multi-domain]  Cd Length: 542  Bit Score: 99.94  E-value: 5.84e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   5 LLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRK-LSNEDKIIATGGGIVQS 83
Cdd:PRK14021  10 VIIGMMGAGKTRVGKEVAQMMRLPFADADVEIEREIGMSIPSYFEEYGEPAFREVEADVVADmLEDFDGIFSLGGGAPMT 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  84 AENRRFLkTQPI-----VLYLEAEADCLVDRIQQDETsiRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTP--- 155
Cdd:PRK14021  90 PSTQHAL-ASYIahggrVVYLDADPKEAMERANRGGG--RPMLNGDANKRWKKLFKQRDPVFRQVANVHVHTRGLTPqaa 166

                        170
                 ....*....|..
gi 488224005 156 -EKIIDTIIERI 166
Cdd:PRK14021 167 aKKLIDMVAERT 178
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 4-168 1.28e-19

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 83.46  E-value: 1.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFHYYGEKSFRKVESDILRKL--SNEDKIIATGGGIV 81
Cdd:PRK08154 136 IALIGLRGAGKSTLGRMLAARLGVPFVELNREIEREAGLSVSEIFALYGQEGYRRLERRALERLiaEHEEMVLATGGGIV 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  82 QSAENRRFLKTQPIVLYLEAEADCLVDRI--QQDetsIRPLALGK-TREEIKALLAQRLSWYEEsATHRINTTNQTPEKI 158
Cdd:PRK08154 216 SEPATFDLLLSHCYTVWLKASPEEHMARVraQGD---LRPMADNReAMEDLRRILASREPLYAR-ADAVVDTSGLTVAQS 291

                        170
                 ....*....|
gi 488224005 159 IDTIIERIKS 168
Cdd:PRK08154 292 LARLRELVRP 301
PLN02199 PLN02199
shikimate kinase
 3-120 1.36e-19

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 83.21  E-value: 1.36e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   3 SILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQ-LSIAEYFHYYGEKSFRKVESDILRKLSNEDK-IIATGGGI 80
Cdd:PLN02199 104 SMYLVGMMGSGKTTVGKLMSKVLGYTFFDCDTLIEQAMNgTSVAEIFVHHGENFFRGKETDALKKLSSRYQvVVSTGGGA 183

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 488224005  81 VQSAENRRFLKtQPIVLYLEAEADCLVDRIQQDETSIRPL 120
Cdd:PLN02199 184 VIRPINWKYMH-KGISIWLDVPLEALAHRIAAVGTDSRPL 222
PRK00625 PRK00625
shikimate kinase; Provisional
 4-146 4.24e-11

shikimate kinase; Provisional


Pssm-ID: 134335 [Multi-domain]  Cd Length: 173  Bit Score: 58.23  E-value: 4.24e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEH----IQLSIAEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGG 79
Cdd:PRK00625   3 IFLCGLPTVGKTSFGKALAKFLSLPFFDTDDLIVSNyhgaLYSSPKEIYQAYGEEGFCREEFLALTSLPVIPSIVALGGG 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 488224005  80 IVQSAENRRFLKTQPIVLYLEAEADCLVDRIQQDETSIRpLALGKTREEIkalLAQRLSWYEESATH 146
Cdd:PRK00625  83 TLMIEPSYAHIRNRGLLVLLSLPIATIYQRLQKRGLPER-LKHAPSLEEI---LSQRIDRMRSIADY 145
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
8-167 5.62e-08

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 49.82  E-value: 5.62e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005   8 GFMGAGKTTIGKGLAQRLQKEYVDLDT--KIEEHIQLSIaEYFHYYGEK-------------SFRKVESDILRKLSNEDK 72
Cdd:COG1102    7 REPGSGGTTIAKRLAEKLGLPLYDGEIlrEAAKERGLSE-EEFEKLDEKapsllyrdtaeedEIDRALDKVIRELARKGN 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005  73 IIATG--GGIVqsaenrrfLKTQPIVL--YLEAEADCLVDRIQQDEtsirplalGKTREEIKALL----AQRLSWYEEsA 144
Cdd:COG1102   86 CVIVGrlADWI--------LRDRPNVLkvFLTAPLEVRVKRIAERE--------GISEEEAEKEIkkrdKSRAKYYKY-Y 148

                        170       180       190
                 ....*....|....*....|....*....|....
gi 488224005 145 THR-----------INTTNQTPEKIIDTIIERIK 167
Cdd:COG1102  149 YGIdwgdpsnydlvINTSRLGIEEAVDLILAAIE 182
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 4-33 7.38e-04

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 38.00  E-value: 7.38e-04
                         10        20        30
                 ....*....|....*....|....*....|
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLD 33
Cdd:cd02021    2 IVVMGVSGSGKSTVGKALAERLGAPFIDGD 31
AAA_18 pfam13238
AAA domain;
4-116 1.01e-03

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 37.41  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224005    4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDTKIEEHIQLSIAEYFhyygeKSFRKVESDILRKLSNEDKIIATGG----- 78
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGFGDNVRDLALENGLVLGDDPET-----RESKRLDEDKLDRLLDLLEENAALEeggnl 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 488224005   79 ---GIVQSAENRRFLKTQPIVLYLEAEAdcLVDRIQQDETS 116
Cdd:pfam13238  76 iidGHLAELEPERAKDLVGIVLRASPEE--LLERLEKRGYE 114
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 3-33 1.66e-03

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 37.03  E-value: 1.66e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 488224005   3 SILLIGFMGAGKTTIGKGLAQRLQKEYVDLD 33
Cdd:COG3265    3 VIVVMGVSGSGKSTVGQALAERLGWPFIDGD 33
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
4-34 1.81e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 37.20  E-value: 1.81e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 488224005   4 ILLIGFMGAGKTTIGKGLAQRLQKEYVDLDT 34
Cdd:COG0645    2 ILVCGLPGSGKSTLARALAERLGAVRLRSDV 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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