|
Name |
Accession |
Description |
Interval |
E-value |
| gpsA |
PRK00094 |
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; |
4-328 |
0e+00 |
|
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase;
Pssm-ID: 234629 [Multi-domain] Cd Length: 325 Bit Score: 541.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQHTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTK 83
Cdd:PRK00094 3 KIAVLGAGSWGTALAIVLARNGHDVTLWARDPEQAAEINADRENPRYLPGIKLPDNLRATTDLAEALADADLILVAVPSQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 84 AIRSVAKELVPKLNTKPVIIHASKGLEQGTHKRISDILLEEIPAEKRkaVVVLSGPSHAEEVAKHDITTITAASTDAKAA 163
Cdd:PRK00094 83 ALREVLKQLKPLLPPDAPIVWATKGIEPGTGKLLSEVLEEELPDLAP--IAVLSGPSFAKEVARGLPTAVVIASTDEELA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 164 KYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGLAEISRLGVAMGANPLTFIGLSG 243
Cdd:PRK00094 161 ERVQELFHSPYFRVYTNTDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEITRLGVALGANPETFLGLAG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 244 IGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLANMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAK 323
Cdd:PRK00094 241 LGDLVLTCTSPLSRNRRFGLALGQGKSLEEALAEIGMVAEGVRTAKAVYELAKKLGVEMPITEAVYAVLYEGKDPREAVE 320
|
....*
gi 488224920 324 EIMLR 328
Cdd:PRK00094 321 DLMGR 325
|
|
| GpsA |
COG0240 |
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ... |
4-331 |
0e+00 |
|
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 440010 [Multi-domain] Cd Length: 327 Bit Score: 541.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQHTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTK 83
Cdd:COG0240 2 KIAVLGAGSWGTALAKVLARNGHEVTLWGRDPEVAEEINETRENPRYLPGVKLPENLRATSDLEEALAGADLVLLAVPSQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 84 AIRSVAKELVPKLNTKPVIIHASKGLEQGTHKRISDILLEEIPAEKRkaVVVLSGPSHAEEVAKHDITTITAASTDAKAA 163
Cdd:COG0240 82 ALREVLEQLAPLLPPGAPVVSATKGIEPGTGLLMSEVIAEELPGALR--IAVLSGPSFAEEVARGLPTAVVVASEDEEVA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 164 KYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGLAEISRLGVAMGANPLTFIGLSG 243
Cdd:COG0240 160 ERLQELLSTPYFRVYTSDDVIGVELGGALKNVIAIAAGIADGLGLGDNARAALITRGLAEMTRLGVALGARPETFMGLAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 244 IGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLANMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAK 323
Cdd:COG0240 240 LGDLVLTCTSDLSRNRRFGLALGKGKSLEEALAEMGMVAEGVYTAKAVYELAEKLGVEMPITEAVYAVLYEGKSPREAVE 319
|
....*...
gi 488224920 324 EIMLRDGK 331
Cdd:COG0240 320 ALMARPLK 327
|
|
| PRK12439 |
PRK12439 |
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional |
4-312 |
2.29e-96 |
|
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
Pssm-ID: 171500 [Multi-domain] Cd Length: 341 Bit Score: 289.38 E-value: 2.29e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVrIWGHRASQVEEINTQHTNQRYLPDHY-LPDSIQAFTNMEDAVKDADAVLFVIPT 82
Cdd:PRK12439 9 KVVVLGGGSWGTTVASICARRGPTL-QWVRSAETADDINDNHRNSRYLGNDVvLSDTLRATTDFAEAANCADVVVMGVPS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 83 KAIRSVAKELVPKLNTKPVIIHASKGLEQGTHKRISDILLEEIPAEkrkAVVVLSGPSHAEEVAKHDITTITAASTDAKA 162
Cdd:PRK12439 88 HGFRGVLTELAKELRPWVPVVSLVKGLEQGTNMRMSQIIEEVLPGH---PAGILAGPNIAREVAEGYAAAAVLAMPDQHL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 163 AKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGLAEISRLGVAMGANPLTFIGLS 242
Cdd:PRK12439 165 ATRLSPLFRTRRFRVYTTDDVVGVEMAGALKNVFAIAVGMGYSLGIGENTRAMVIARALREMTKLGVAMGGNPETFAGLA 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 243 GIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLANMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVL 312
Cdd:PRK12439 245 GMGDLIVTCTSQRSRNRHVGEQLGAGKPIDEIIASMNQVAEGVKAASVVMEFADEYGLNMPIAREVDAVI 314
|
|
| PRK14619 |
PRK14619 |
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional |
4-333 |
1.29e-93 |
|
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
Pssm-ID: 237771 [Multi-domain] Cd Length: 308 Bit Score: 281.11 E-value: 1.29e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQveeintqhtnqrylpdhylpdsiqaftNMEDAVKDADAVLFVIPTK 83
Cdd:PRK14619 6 TIAILGAGAWGSTLAGLASANGHRVRVWSRRSGL---------------------------SLAAVLADADVIVSAVSMK 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 84 AIRSVAkELVPKLNTKP--VIIHASKGLEQGTHKRISDILLEEIPAEkrkAVVVLSGPSHAEEVAKHDITTITAASTDAK 161
Cdd:PRK14619 59 GVRPVA-EQVQALNLPPetIIVTATKGLDPETTRTPSQIWQAAFPNH---PVVVLSGPNLSKEIQQGLPAATVVASRDLA 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 162 AAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGLAEISRLGVAMGANPLTFIGL 241
Cdd:PRK14619 135 AAETVQQIFSSERFRVYTNSDPLGTELGGTLKNVIAIAAGVCDGLQLGTNAKAALVTRALPEMIRVGTHLGAQTETFYGL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 242 SGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLANMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTA 321
Cdd:PRK14619 215 SGLGDLLATCTSPLSRNYQVGYGLAQGKSLEQILAELEGTAEGVNTANVLVQLAQQQNIAVPITEQVYRLLQGEITPQQA 294
|
330
....*....|..
gi 488224920 322 AKEIMLRDGKKE 333
Cdd:PRK14619 295 LEELMERDLKPE 306
|
|
| PRK14618 |
PRK14618 |
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional |
4-333 |
6.54e-87 |
|
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
Pssm-ID: 237770 [Multi-domain] Cd Length: 328 Bit Score: 264.81 E-value: 6.54e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQHTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTK 83
Cdd:PRK14618 6 RVAVLGAGAWGTALAVLAASKGVPVRLWARRPEFAAALAAERENREYLPGVALPAELYPTADPEEALAGADFAVVAVPSK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 84 AIRsvakELVPKLNTKPVIIHASKGLeQGTHKRISDiLLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDAKAA 163
Cdd:PRK14618 86 ALR----ETLAGLPRALGYVSCAKGL-APDGGRLSE-LARVLEFLTQARVAVLSGPNHAEEIARFLPAATVVASPEPGLA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 164 KYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGLAEISRLGVAMGANPLTFIGLSG 243
Cdd:PRK14618 160 RRVQAAFSGPSFRVYTSRDRVGVELGGALKNVIALAAGMVDGLKLGDNAKAALITRGLREMVRFGVALGAEEATFYGLSG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 244 IGDLVVTCTSVHSRNWRAGNLLGQGQPLEEvLANMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAK 323
Cdd:PRK14618 240 LGDLIATATSPHSRNRAAGEAIVRGVDREH-LEAGGKVVEGLYTVKALDAWAKAHGHDLPIVEAVARVARGGWDPLAGLR 318
|
330
....*....|
gi 488224920 324 EIMLRDGKKE 333
Cdd:PRK14618 319 SLMGREAKEE 328
|
|
| NAD_Gly3P_dh_C |
pfam07479 |
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent ... |
182-323 |
1.04e-81 |
|
NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the C-terminal substrate-binding domain.
Pssm-ID: 462178 [Multi-domain] Cd Length: 142 Bit Score: 244.61 E-value: 1.04e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 182 DVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRA 261
Cdd:pfam07479 1 DVIGVELGGALKNVIAIAAGIADGLGLGDNAKAALITRGLAEMIRLGKALGAKPETFFGLAGLGDLIVTCTSGLSRNRRF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488224920 262 GNLLGQGQPLEEVLANMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAK 323
Cdd:pfam07479 81 GEALGKGKSLEEAEKELGQVAEGVYTAKAVYELAKKLGVEMPIFEAVYRILYEGKSPEEALE 142
|
|
| NAD_Gly3P_dh_N |
pfam01210 |
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent ... |
5-163 |
2.41e-76 |
|
NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH) catalyzes the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate. This family represents the N-terminal NAD-binding domain.
Pssm-ID: 395967 [Multi-domain] Cd Length: 158 Bit Score: 231.70 E-value: 2.41e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 5 VAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQHTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKA 84
Cdd:pfam01210 2 IAVLGAGSWGTALAKVLADNGHEVRLWGRDEELIEEINTTHENVRYLPGIKLPENLKATTDLAEALKGADIIVIVVPSQA 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 488224920 85 IRSVAKELVPKLNTKPVIIHASKGLEQGTHKRISDILLEEIPAEKRkaVVVLSGPSHAEEVAKHDITTITAASTDAKAA 163
Cdd:pfam01210 82 LREVLKQLKGLLKPDAILVSLSKGIEPGTLKLLSEVIEEELGIQPP--IAVLSGPSHAEEVAQGLPTATVIASKDEEAA 158
|
|
| glycerol3P_DH |
TIGR03376 |
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic ... |
4-319 |
1.20e-73 |
|
glycerol-3-phosphate dehydrogenase (NAD(+)); Members of this protein family are the eukaryotic enzyme, glycerol-3-phosphate dehydrogenase (NAD(+)) (EC 1.1.1.8). Enzymatic activity for 1.1.1.8 is defined as sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH. Note the very similar reactions of enzymes defined as EC 1.1.1.94 and 1.1.99.5, assigned to families of proteins in the bacteria.
Pssm-ID: 274551 [Multi-domain] Cd Length: 342 Bit Score: 231.08 E-value: 1.20e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENG--------HDVRIWgHRASQVEE------INTQHTNQRYLPDHYLPDSIQAFTNMEDA 69
Cdd:TIGR03376 1 RVAVVGSGNWGTAIAKIVAENAralpelfeESVRMW-VFEEEIEGrnlteiINTTHENVKYLPGIKLPANLVAVPDLVEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 70 VKDADAVLFVIPTKAIRSVAKELVPKLNTKPVIIHASKGLEQGTH--KRISDILLEE--IPaekrkaVVVLSGPSHAEEV 145
Cdd:TIGR03376 80 AKGADILVFVIPHQFLEGICKQLKGHVKPNARAISCIKGLEVSKDgvKLLSDIIEEElgIP------CGVLSGANLANEV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 146 AKHDITTITAASTDAKAAKY----VQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGL 221
Cdd:TIGR03376 154 AKEKFSETTVGYRDPADFDVdarvLKALFHRPYFRVNVVDDVAGVEIAGALKNVVAIAAGFVDGLGWGDNAKAAVMRRGL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 222 AEISRLGVAM-GANPLTFI-GLSGIGDLVVTCTSvhSRNWRAGNLLGQ-GQPLEEVLANM--GMVVEGVNTTQAAMELAQ 296
Cdd:TIGR03376 234 LEMIKFARMFfPTGEVTFTfESCGVADLITTCLG--GRNFKVGRAFAKtGKSLEELEKELlnGQSLQGVATAKEVHELLK 311
|
330 340
....*....|....*....|....*
gi 488224920 297 M--MEIEMPITQTIYEVLYEQKEIK 319
Cdd:TIGR03376 312 NknKDDEFPLFEAVYQILYEGLPPK 336
|
|
| PRK14620 |
PRK14620 |
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional |
4-326 |
5.19e-73 |
|
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional
Pssm-ID: 173083 [Multi-domain] Cd Length: 326 Bit Score: 228.95 E-value: 5.19e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQHTNQRYLPDHYLPDSIQAFTNMEDAVKD-ADAVLFVIPT 82
Cdd:PRK14620 2 KISILGAGSFGTAIAIALSSKKISVNLWGRNHTTFESINTKRKNLKYLPTCHLPDNISVKSAIDEVLSDnATCIILAVPT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 83 KAIRSVAKELV-PKLNTKPVIIHASKGLEQGTHKRISDILLEEIPaekRKAVVVLSGPSHAEEVAKH-DITTITAASTDA 160
Cdd:PRK14620 82 QQLRTICQQLQdCHLKKNTPILICSKGIEKSSLKFPSEIVNEILP---NNPIAILSGPSFAKEIAEKlPCSIVLAGQNET 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 161 KAAKYVQELfMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGLAEISRLGVAMGANP--LTF 238
Cdd:PRK14620 159 LGSSLISKL-SNENLKIIYSQDIIGVQIGAALKNIIAIACGIVLGKNLGNNAHAAVITKGMNEIKTLYSAKNGSIdlNTL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 239 IGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLANMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEI 318
Cdd:PRK14620 238 IGPSCLGDLILTCTTLHSRNMSFGFKIGNGFNINQILSEGKSVIEGFSTVKPLISLAKKLNIELPICESIYNLLYENISL 317
|
....*...
gi 488224920 319 KTAAKEIM 326
Cdd:PRK14620 318 EKTISVIL 325
|
|
| PTZ00345 |
PTZ00345 |
glycerol-3-phosphate dehydrogenase; Provisional |
4-317 |
1.67e-57 |
|
glycerol-3-phosphate dehydrogenase; Provisional
Pssm-ID: 240373 [Multi-domain] Cd Length: 365 Bit Score: 190.23 E-value: 1.67e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGH-------DVRIW-------GHRASQVeeINTQHTNQRYLPDHYLPDSIQAFTNMEDA 69
Cdd:PTZ00345 13 KVSVIGSGNWGSAISKVVGENTQrnyifhnEVRMWvleeiveGEKLSDI--INTKHENVKYLPGIKLPDNIVAVSDLKEA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 70 VKDADAVLFVIPTKAIRSVAKELVPKLNTKP--VIIHASKGL--EQGTHKRISDILLEEIPAEkrkaVVVLSGPSHAEEV 145
Cdd:PTZ00345 91 VEDADLLIFVIPHQFLESVLSQIKENNNLKKhaRAISLTKGIivENGKPVLCSDVIEEELGIP----CCALSGANVANDV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 146 AKHDITTITAASTDAKAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMTRGLAEIS 225
Cdd:PTZ00345 167 AREEFSEATIGCEDKDDALIWQRLFDRPYFKINCVPDVIGVEVCGALKNIIALAAGFCDGLGLGTNTKSAIIRIGLEEMK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 226 RLGVAMGANPL--TFIGLSGIGDLVVTCTSvhSRNWRAGN--LLGQGQ-PLEEVLANM--GMVVEGVNTTQAAMEL--AQ 296
Cdd:PTZ00345 247 LFGKIFFPNVMdeTFFESCGLADLITTCLG--GRNVRCAAefAKRNGKkSWEEIEAELlnGQKLQGTVTLKEVYEVleSH 324
|
330 340
....*....|....*....|.
gi 488224920 297 MMEIEMPITQTIYEVLYEQKE 317
Cdd:PTZ00345 325 DLKKEFPLFTVTYKIAFEGAD 345
|
|
| GPD_NAD_C_bact |
pfam20618 |
Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent ... |
242-308 |
1.40e-22 |
|
Bacterial GPD, NAD-dependent C-terminal; This is the C-terminal domain of NAD-dependent glycerol-3-phosphate dehydrogenase (GPD) from bacteria and archaea. GPD catalyzes the reversible reduction of dihydroxyacetone phosphate to glycerol-3-phosphate.
Pssm-ID: 466767 [Multi-domain] Cd Length: 66 Bit Score: 89.48 E-value: 1.40e-22
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 488224920 242 SGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEvlANMGMVVEGVNTTQAAME-LAQMMEIEMPITQTI 308
Cdd:pfam20618 1 AGLGDLVLTCTSDLSRNRTFGLLLGKGMTLAE--AGNGQVAEGVRTAKAVAAiLARAHNVEMPILEAV 66
|
|
| COG2085 |
COG2085 |
Predicted dinucleotide-binding enzyme [General function prediction only]; |
5-102 |
3.10e-08 |
|
Predicted dinucleotide-binding enzyme [General function prediction only];
Pssm-ID: 441688 [Multi-domain] Cd Length: 205 Bit Score: 53.25 E-value: 3.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 5 VAVLGPGSWGTALAQVLAENGHDVRIwGHR-----ASQVEEINtqhtnqrylpdhylpDSIQAFTNmEDAVKDADAVLFV 79
Cdd:COG2085 1 IGIIGTGNIGSALARRLAAAGHEVVI-GSRdpekaAALAAELG---------------PGARAGTN-AEAAAAADVVVLA 63
|
90 100
....*....|....*....|...
gi 488224920 80 IPTKAIRSVAKELVPKLNTKPVI 102
Cdd:COG2085 64 VPYEAVPDVLESLGDALAGKIVI 86
|
|
| COG5495 |
COG5495 |
Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains ... |
1-106 |
4.91e-07 |
|
Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains [General function prediction only];
Pssm-ID: 444246 [Multi-domain] Cd Length: 286 Bit Score: 50.58 E-value: 4.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 1 MNYRVAVLGPGSWGTALAQVLAENGHDVR-IWGHRASQVEEIntqhtnQRYLPdhylpdsIQAFTNMEDAVKDADAVLFV 79
Cdd:COG5495 2 ARMKIGIIGAGRVGTALAAALRAAGHEVVgVYSRSPASAERA------AALLG-------AVPALDLEELAAEADLVLLA 68
|
90 100
....*....|....*....|....*....
gi 488224920 80 IPTKAIRSVAKELVPKLNTKP--VIIHAS 106
Cdd:COG5495 69 VPDDAIAEVAAGLAAAGALRPgqLVVHTS 97
|
|
| ProC |
COG0345 |
Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; ... |
1-103 |
6.54e-07 |
|
Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Pyrroline-5-carboxylate reductase is part of the Pathway/BioSystem: Proline biosynthesis
Pssm-ID: 440114 [Multi-domain] Cd Length: 267 Bit Score: 50.06 E-value: 6.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 1 MNYRVAVLGPGSWGTALAQVLAENG---HDVRIWGHRASQVEEINTQHtnqrylpdhylpdSIQAFTNMEDAVKDADAVL 77
Cdd:COG0345 1 MSMKIGFIGAGNMGSAIIKGLLKSGvppEDIIVSDRSPERLEALAERY-------------GVRVTTDNAEAAAQADVVV 67
|
90 100
....*....|....*....|....*.
gi 488224920 78 FVIPTKAIRSVAKELVPKLNTKPVII 103
Cdd:COG0345 68 LAVKPQDLAEVLEELAPLLDPDKLVI 93
|
|
| PanE |
COG1893 |
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of ... |
4-235 |
8.65e-07 |
|
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Pssm-ID: 441497 [Multi-domain] Cd Length: 305 Bit Score: 49.86 E-value: 8.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGhRASQVEEINTQHTNQRYLPDHYLPDSIQAFTNmEDAVKDADAVLFVIPTK 83
Cdd:COG1893 2 KIAILGAGAIGGLLGARLARAGHDVTLVA-RGAHAEALRENGLRLESPDGDRTTVPVPAVTD-PEELGPADLVLVAVKAY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 84 AIRSVAKELVPKLNTKPVIIHASKGLEQGthkrisDILLEEIPAEKRKAVVV-----LSGPSHAEEVAKHDITTITAAST 158
Cdd:COG1893 80 DLEAAAEALAPLLGPDTVVLSLQNGLGHE------ERLAEALGAERVLGGVVtigatREEPGVVRHTGGGRLVLGELDGG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 159 DAKAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFG---DNAKA-AIMTRGLAEISRLGVAMGAN 234
Cdd:COG1893 154 PSERLEALAELLEAAGIPVEVSDDIRGALWEKLLLNAAINPLTALTGAPNGellADPEArALARALMREVLAVARAEGVP 233
|
.
gi 488224920 235 P 235
Cdd:COG1893 234 L 234
|
|
| PRK08229 |
PRK08229 |
2-dehydropantoate 2-reductase; Provisional |
1-138 |
9.37e-07 |
|
2-dehydropantoate 2-reductase; Provisional
Pssm-ID: 236193 [Multi-domain] Cd Length: 341 Bit Score: 50.00 E-value: 9.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 1 MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGhRASQVEEInTQH----TNQRYLPDHYLPDSIqAFTNMEDAVKDADAV 76
Cdd:PRK08229 1 MMARICVLGAGSIGCYLGGRLAAAGADVTLIG-RARIGDEL-RAHgltlTDYRGRDVRVPPSAI-AFSTDPAALATADLV 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488224920 77 LFVIPTKAIRSVAKELVPKLNTKPVIIHASKGLEQgthkriSDILLEEIPaekrkAVVVLSG 138
Cdd:PRK08229 78 LVTVKSAATADAAAALAGHARPGAVVVSFQNGVRN------ADVLRAALP-----GATVLAG 128
|
|
| F420_oxidored |
pfam03807 |
NADP oxidoreductase coenzyme F420-dependent; |
6-102 |
3.93e-05 |
|
NADP oxidoreductase coenzyme F420-dependent;
Pssm-ID: 397743 [Multi-domain] Cd Length: 92 Bit Score: 41.83 E-value: 3.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 6 AVLGPGSWGTALAQVLAENG-HDVRIWGHRAsqVEEIntqhtnqRYLPDHYLPDsIQAFTNmEDAVKDADAVLFVIPTKA 84
Cdd:pfam03807 1 GFIGAGNMGEALARGLVAAGpHEVVVANSRN--PEKA-------EELAEEYGVG-ATAVDN-EEAAEEADVVFLAVKPED 69
|
90
....*....|....*...
gi 488224920 85 IRSVAKELVPKLNTKPVI 102
Cdd:pfam03807 70 APDVLSELSDLLKGKIVI 87
|
|
| PRK07502 |
PRK07502 |
prephenate/arogenate dehydrogenase family protein; |
4-100 |
5.10e-05 |
|
prephenate/arogenate dehydrogenase family protein;
Pssm-ID: 236034 [Multi-domain] Cd Length: 307 Bit Score: 44.58 E-value: 5.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQ-----VEEINtqhtnqryLPDHYLPDSiqaftnmEDAVKDADAVLF 78
Cdd:PRK07502 8 RVALIGIGLIGSSLARAIRRLGLAGEIVGADRSAetrarARELG--------LGDRVTTSA-------AEAVKGADLVIL 72
|
90 100
....*....|....*....|..
gi 488224920 79 VIPTKAIRSVAKELVPKLntKP 100
Cdd:PRK07502 73 CVPVGASGAVAAEIAPHL--KP 92
|
|
| TyrA |
COG0287 |
Prephenate dehydrogenase [Amino acid transport and metabolism]; Prephenate dehydrogenase is ... |
4-103 |
7.78e-05 |
|
Prephenate dehydrogenase [Amino acid transport and metabolism]; Prephenate dehydrogenase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 440056 [Multi-domain] Cd Length: 278 Bit Score: 43.58 E-value: 7.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASqveEINTQHTNQRYLPDhylpdsiQAFTNMEDAVKDADAVLFVIPTK 83
Cdd:COG0287 3 RIAIIGLGLIGGSLALALKRAGLAHEVVGVDRS---PETLERALELGVID-------RAATDLEEAVADADLVVLAVPVG 72
|
90 100
....*....|....*....|
gi 488224920 84 AIRSVAKELVPKLNTKPVII 103
Cdd:COG0287 73 ATIEVLAELAPHLKPGAIVT 92
|
|
| NAD_binding_2 |
pfam03446 |
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of ... |
4-103 |
1.47e-04 |
|
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold.
Pssm-ID: 427298 [Multi-domain] Cd Length: 159 Bit Score: 41.69 E-value: 1.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEIntqhtnqrylpdhyLPDSIQAFTNMEDAVKDADAVLFVIP-T 82
Cdd:pfam03446 1 KIGFIGLGVMGSPMALNLLKAGYTVTVYNRTPEKVEEL--------------VAAGAIAAASPAEFVAGLDVVITMVPaG 66
|
90 100
....*....|....*....|...
gi 488224920 83 KAIRSVAKE--LVPKLNTKPVII 103
Cdd:pfam03446 67 AAVDAVIFGegLLPGLKPGDIII 89
|
|
| PRK06129 |
PRK06129 |
3-hydroxyacyl-CoA dehydrogenase; Validated |
4-76 |
5.04e-04 |
|
3-hydroxyacyl-CoA dehydrogenase; Validated
Pssm-ID: 235706 [Multi-domain] Cd Length: 308 Bit Score: 41.18 E-value: 5.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQHtnQRYLPD--------HYLPDS----IQAFTNMEDAVK 71
Cdd:PRK06129 4 SVAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYI--AGRLEDlaafdlldGEAPDAvlarIRVTDSLADAVA 81
|
....*
gi 488224920 72 DADAV 76
Cdd:PRK06129 82 DADYV 86
|
|
| ApbA |
pfam02558 |
Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also ... |
5-103 |
8.84e-04 |
|
Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also known as ketopantoate reductases, EC:1.1.1.169. The reaction catalyzed by this enzyme is: (R)-pantoate + NADP(+) <=> 2-dehydropantoate + NADPH. AbpA catalyzes the NADPH reduction of ketopantoic acid to pantoic acid in the alternative pyrimidine biosynthetic (APB) pathway. ApbA and PanE are allelic. ApbA, the ketopantoate reductase enzyme is required for the synthesis of thiamine via the APB biosynthetic pathway.
Pssm-ID: 426831 [Multi-domain] Cd Length: 147 Bit Score: 39.14 E-value: 8.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 5 VAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVE------EINTQHTNQRYLPDHYLPDsiqaftnmEDAVKDADAVLF 78
Cdd:pfam02558 1 IAILGAGAIGSLLGARLAKAGHDVTLILRGAELAAikknglRLTSPGGERIVPPPAVTSA--------SESLGPIDLVIV 72
|
90 100
....*....|....*....|....*
gi 488224920 79 VIPTKAIRSVAKELVPKLNTKPVII 103
Cdd:pfam02558 73 TVKAYQTEEALEDIAPLLGPNTVVL 97
|
|
| PRK08655 |
PRK08655 |
prephenate dehydrogenase; Provisional |
9-95 |
1.98e-03 |
|
prephenate dehydrogenase; Provisional
Pssm-ID: 236326 [Multi-domain] Cd Length: 437 Bit Score: 39.59 E-value: 1.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 9 GPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQhtnqryLPDHYLPDSIqaftnmeDAVKDADAVLFVIPTKAIRSV 88
Cdd:PRK08655 8 GTGGLGKWFARFLKEKGFEVIVTGRDPKKGKEVAKE------LGVEYANDNI-------DAAKDADIVIISVPINVTEDV 74
|
....*..
gi 488224920 89 AKELVPK 95
Cdd:PRK08655 75 IKEVAPH 81
|
|
| PRK12921 |
PRK12921 |
oxidoreductase; |
4-111 |
2.00e-03 |
|
oxidoreductase;
Pssm-ID: 183829 [Multi-domain] Cd Length: 305 Bit Score: 39.46 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLGPGSWGTALAQVLAENGHDVRIWGhRASQVEEinTQHTNQRYLPDH---YLPdsIQAFTNMEDAVKDADAVLFVI 80
Cdd:PRK12921 2 RIAVVGAGAVGGTFGGRLLEAGRDVTFLV-RPKRAKA--LRERGLVIRSDHgdaVVP--GPVITDPEELTGPFDLVILAV 76
|
90 100 110
....*....|....*....|....*....|.
gi 488224920 81 PTKAIRSVAKELVPKLNTKPVIIHASKGLEQ 111
Cdd:PRK12921 77 KAYQLDAAIPDLKPLVGEDTVIIPLQNGIGQ 107
|
|
| SsuE |
COG0431 |
NAD(P)H-dependent FMN reductase [Energy production and conversion]; |
4-81 |
7.95e-03 |
|
NAD(P)H-dependent FMN reductase [Energy production and conversion];
Pssm-ID: 440200 [Multi-domain] Cd Length: 162 Bit Score: 36.67 E-value: 7.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488224920 4 RVAVLG----PGSWGTALAQVLAE----NGHDVRIWghrasQVEEINTQHTNQRyLPDHYLPDSIQAFTnmeDAVKDADA 75
Cdd:COG0431 2 KILVISgslrPGSFNRKLARAAAElapaAGAEVELI-----DLRDLDLPLYDED-LEADGAPPAVKALR---EAIAAADG 72
|
....*.
gi 488224920 76 VLFVIP 81
Cdd:COG0431 73 VVIVTP 78
|
|
| |
