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Conserved domains on  [gi|488238073|ref|WP_002309281|]
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MULTISPECIES: AbrB/MazE/SpoVT family DNA-binding domain-containing protein [Enterococcus]

Protein Classification

AbrB/MazE/SpoVT family DNA-binding domain-containing protein( domain architecture ID 10021162)

AbrB/MazE/SpoVT family DNA-binding domain-containing protein similar to bacterial addiction module antidote protein

CATH:  2.10.260.10
Gene Ontology:  GO:0003677
SCOP:  4000397

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
doc_partner TIGR02609
putative addiction module antidote; Members of this protein family are putative addiction ...
 12-77 1.93e-20

putative addiction module antidote; Members of this protein family are putative addiction module antidote proteins that appear recurringly in two-gene operons with members of the Doc (death-on-curing) family TIGR01550. Members of this family contain a SpoVT/AbrB-like domain (pfam04014). Note that the gene pairs with a member of this family tend to be found on bacterial chromosomes, not on plasmids. [Mobile and extrachromosomal element functions, Other]


:

Pssm-ID: 274230  Cd Length: 74  Bit Score: 76.65  E-value: 1.93e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488238073  12 SGNSDVTTIPPEVKEFMGVQTGDAIsYVFQSDGSVRMIKAQE----EPDIDLLVDSIMNQYEDALKDLVD 77
Cdd:TIGR02609  6 VGNSLVVTLPKEVLESLGLKEGDTL-YVDEEEGGLKLKRFDEgkelEKKMQMAVERAMSKYDEALKELAD 74
 
Name Accession Description Interval E-value
doc_partner TIGR02609
putative addiction module antidote; Members of this protein family are putative addiction ...
 12-77 1.93e-20

putative addiction module antidote; Members of this protein family are putative addiction module antidote proteins that appear recurringly in two-gene operons with members of the Doc (death-on-curing) family TIGR01550. Members of this family contain a SpoVT/AbrB-like domain (pfam04014). Note that the gene pairs with a member of this family tend to be found on bacterial chromosomes, not on plasmids. [Mobile and extrachromosomal element functions, Other]


Pssm-ID: 274230  Cd Length: 74  Bit Score: 76.65  E-value: 1.93e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488238073  12 SGNSDVTTIPPEVKEFMGVQTGDAIsYVFQSDGSVRMIKAQE----EPDIDLLVDSIMNQYEDALKDLVD 77
Cdd:TIGR02609  6 VGNSLVVTLPKEVLESLGLKEGDTL-YVDEEEGGLKLKRFDEgkelEKKMQMAVERAMSKYDEALKELAD 74
PRK09974 PRK09974
type II toxin-antitoxin system PrlF family antitoxin;
18-72 7.23e-03

type II toxin-antitoxin system PrlF family antitoxin;


Pssm-ID: 236638  Cd Length: 111  Bit Score: 32.33  E-value: 7.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 488238073  18 TTIPPEVKEFMGVQTGDAISYVFQSDGSVRMIKAQEEPDidllvDSIMNQYEDAL 72
Cdd:PRK09974  20 TTVPAPVRKALKLKKRDSIHYEILPGGQVFICRLGDEEE-----DPVLGAFLDFL 69
 
Name Accession Description Interval E-value
doc_partner TIGR02609
putative addiction module antidote; Members of this protein family are putative addiction ...
 12-77 1.93e-20

putative addiction module antidote; Members of this protein family are putative addiction module antidote proteins that appear recurringly in two-gene operons with members of the Doc (death-on-curing) family TIGR01550. Members of this family contain a SpoVT/AbrB-like domain (pfam04014). Note that the gene pairs with a member of this family tend to be found on bacterial chromosomes, not on plasmids. [Mobile and extrachromosomal element functions, Other]


Pssm-ID: 274230  Cd Length: 74  Bit Score: 76.65  E-value: 1.93e-20
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488238073  12 SGNSDVTTIPPEVKEFMGVQTGDAIsYVFQSDGSVRMIKAQE----EPDIDLLVDSIMNQYEDALKDLVD 77
Cdd:TIGR02609  6 VGNSLVVTLPKEVLESLGLKEGDTL-YVDEEEGGLKLKRFDEgkelEKKMQMAVERAMSKYDEALKELAD 74
PRK09974 PRK09974
type II toxin-antitoxin system PrlF family antitoxin;
18-72 7.23e-03

type II toxin-antitoxin system PrlF family antitoxin;


Pssm-ID: 236638  Cd Length: 111  Bit Score: 32.33  E-value: 7.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 488238073  18 TTIPPEVKEFMGVQTGDAISYVFQSDGSVRMIKAQEEPDidllvDSIMNQYEDAL 72
Cdd:PRK09974  20 TTVPAPVRKALKLKKRDSIHYEILPGGQVFICRLGDEEE-----DPVLGAFLDFL 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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