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Conserved domains on  [gi|488251006|ref|WP_002322214|]
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MULTISPECIES: helix-turn-helix domain-containing protein [Bacillati]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11443570)

helix-turn-helix domain-containing protein such as an XRE (Xenobiotic Response Element) family transcriptional regulator

Gene Ontology:  GO:0003677
PubMed:  37972151

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-73 4.17e-22

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 86.20  E-value: 4.17e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488251006   1 MEHYEKKIsflGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSGE 73
Cdd:COG1396    1 MSTLKKAL---GERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGA 70
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-73 4.17e-22

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 86.20  E-value: 4.17e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488251006   1 MEHYEKKIsflGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSGE 73
Cdd:COG1396    1 MSTLKKAL---GERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGA 70
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 12-69 4.90e-17

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 72.20  E-value: 4.90e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488251006  12 GENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNEL 69
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
14-69 1.48e-15

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 68.31  E-value: 1.48e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 488251006    14 NIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNEL 69
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 15-69 1.72e-14

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 65.25  E-value: 1.72e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 488251006   15 IQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNEL 69
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 11-65 3.23e-08

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 48.81  E-value: 3.23e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 488251006   11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVT 65
Cdd:TIGR03070   3 IGILVRARRKALGLTQADLADLAGVGLRFIRDLENGKPTVRLDKVLRVLDALGLE 57
PRK09943 PRK09943
HTH-type transcriptional regulator PuuR;
12-71 1.54e-05

HTH-type transcriptional regulator PuuR;


Pssm-ID: 182158 [Multi-domain]  Cd Length: 185  Bit Score: 44.01  E-value: 1.54e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488251006  12 GENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLS 71
Cdd:PRK09943   9 GKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSEFFS 68
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-73 4.17e-22

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 86.20  E-value: 4.17e-22
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488251006   1 MEHYEKKIsflGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSGE 73
Cdd:COG1396    1 MSTLKKAL---GERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSLETLLKLAKALGVSLDELLGGA 70
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
11-73 2.01e-17

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 73.34  E-value: 2.01e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488251006  11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSGE 73
Cdd:COG1476    5 LGNRLKELRKERGLTQEELAELLGVSRQTISAIENGKYNPSLELALKIARALGVSLEELFSLE 67
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 12-69 4.90e-17

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 72.20  E-value: 4.90e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488251006  12 GENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNEL 69
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
14-69 1.48e-15

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 68.31  E-value: 1.48e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 488251006    14 NIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNEL 69
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKLAKALGVSLDEL 56
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 15-69 1.72e-14

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 65.25  E-value: 1.72e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 488251006   15 IQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNEL 69
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGKREPSLETLKKLAEALGVSLDEL 55
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 11-68 3.47e-13

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 62.26  E-value: 3.47e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488251006  11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNE 68
Cdd:COG1813   13 YGERIREAREARGLSQEELAEKLGVSESTIRRIERGEATPSLDTLRKLEKALGISLAE 70
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
14-70 6.38e-12

DNA-binding transcriptional regulator, XRE family [Transcription];


Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 59.00  E-value: 6.38e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 488251006  14 NIQTIRKHRGMKQQELADKIGINMQSLSKIERG-VNYPTFDTLEKIMDVLGVTPNELL 70
Cdd:COG3655    5 KLDELLAERGMTKKELAEATGISRATLSRLKNGkAKAVRLDTLEKICKALDCQPGDLL 62
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 11-70 1.47e-11

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 58.88  E-value: 1.47e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488251006  11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELL 70
Cdd:COG3620   18 LGEALRLMRKELGLSQLPVAELVGVSQSDILRIESGKRDPTVSTLEKIAEALGKELSAVL 77
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
 14-70 2.12e-11

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 57.55  E-value: 2.12e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 488251006   14 NIQTIRKHRGMKQQELADKIGINMQSLSKIERG-VNYPTFDTLEKIMDVLGVTPNELL 70
Cdd:pfam13443   1 KLRKLMADRGISKSDLARATGISRATLSRLRKGkPKRVSLDTLDKICDALGCQPGDLL 58
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 12-73 3.43e-11

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 56.91  E-value: 3.43e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 488251006   12 GENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSGE 73
Cdd:pfam12844   1 GERLRKAREERGLTQEELAERLGISRSQLSAIENGKSVPPAETLYKIAELLGVPANWLLQGE 62
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 11-69 2.12e-08

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 49.45  E-value: 2.12e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488251006   11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERG-VNYPTFDTLEKIMDVLGVTPNEL 69
Cdd:pfam13560   2 LGARLRRLRERAGLSQEALARRLGVSRSTLSRLETGrRGRPSPAVVERLARALGVDGAER 61
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 11-65 3.23e-08

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 48.81  E-value: 3.23e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 488251006   11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVT 65
Cdd:TIGR03070   3 IGILVRARRKALGLTQADLADLAGVGLRFIRDLENGKPTVRLDKVLRVLDALGLE 57
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
6-51 1.06e-05

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 41.84  E-value: 1.06e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 488251006   6 KKISFLGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPT 51
Cdd:COG2944    2 TKKPLTPEEIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPS 47
PRK09943 PRK09943
HTH-type transcriptional regulator PuuR;
12-71 1.54e-05

HTH-type transcriptional regulator PuuR;


Pssm-ID: 182158 [Multi-domain]  Cd Length: 185  Bit Score: 44.01  E-value: 1.54e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 488251006  12 GENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLS 71
Cdd:PRK09943   9 GKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSEFFS 68
PA5055 COG3636
Uncharacterized Zn-binding protein, DUF971 domain [Mobilome: prophages, transposons];
15-64 2.13e-05

Uncharacterized Zn-binding protein, DUF971 domain [Mobilome: prophages, transposons];


Pssm-ID: 442853  Cd Length: 92  Bit Score: 41.69  E-value: 2.13e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 488251006  15 IQTIRKHRGMKQqeLADKIGINMQSLSKI--ERGvNyPTFDTLEKIMDVLGV 64
Cdd:COG3636   41 LGDVARARGMSQ--LAKEAGLSRESLYKAlsPKG-N-PTLDTLLKVLKALGL 88
PRK09706 PRK09706
transcriptional repressor DicA; Reviewed
 11-73 3.34e-05

transcriptional repressor DicA; Reviewed


Pssm-ID: 182039 [Multi-domain]  Cd Length: 135  Bit Score: 42.15  E-value: 3.34e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 488251006  11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSGE 73
Cdd:PRK09706   6 LGQRIRYRRKQLKLSQRSLAKAVKVSHVSISQWERDETEPTGKNLFALAKALQCSPTWLLFGD 68
PHA01976 PHA01976
helix-turn-helix protein
 18-72 8.68e-05

helix-turn-helix protein


Pssm-ID: 177330 [Multi-domain]  Cd Length: 67  Bit Score: 39.55  E-value: 8.68e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 488251006  18 IRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSG 72
Cdd:PHA01976  10 ARNARAWSAPELSRRAGVRHSLIYDFEADKRLPNLKTLLRLADALGVTLDWLCGR 64
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
 11-70 8.81e-05

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 39.40  E-value: 8.81e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488251006  11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERG----VNYPTF--DTLEKIMDVLGVTPNELL 70
Cdd:COG1426    6 IGELLRQAREAKGLSLEDVAERTKISVSYLEAIEEGdfdaLPGPVYvrGFLRSYARALGLDPEELL 71
PRK13890 PRK13890
conjugal transfer protein TrbA; Provisional
 14-70 1.04e-04

conjugal transfer protein TrbA; Provisional


Pssm-ID: 237547 [Multi-domain]  Cd Length: 120  Bit Score: 40.51  E-value: 1.04e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 488251006  14 NIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGvTPNELL 70
Cdd:PRK13890   9 NVLRLLDERHMTKKELSERSGVSISFLSDLTTGKANPSLKVMEAIADALE-TPLPLL 64
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
 22-76 1.85e-04

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 39.02  E-value: 1.85e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 488251006  22 RGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSGEWKY 76
Cdd:COG3093   21 LGLSQTELAKALGVSRQRISEILNGKRAITADTALRLARAFGTSAEFWLNLQAAY 75
dnstrm_HI1420 TIGR02684
probable addiction module antidote protein; Members of this strictly bacterial protein family ...
 15-64 4.74e-04

probable addiction module antidote protein; Members of this strictly bacterial protein family are small, at roughly 100 amino acids. The gene is almost invariably the downstream member of a gene pair. It is a predicted DNA-binding protein from a clade within Pfam helix-turn-helix family pfam01381. These gene pairs, when found on the bacterial chromosome, are located often with prophage regions, but also both in integrated plasmid regions and in housekeeping gene regions. Analysis suggests that the gene pair may serve as an addiction module. [Mobile and extrachromosomal element functions, Other]


Pssm-ID: 188241  Cd Length: 89  Bit Score: 38.08  E-value: 4.74e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 488251006   15 IQTIRKHRGMKQqeLADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGV 64
Cdd:TIGR02684  37 LGYIARARGMTQ--LAKKTGLSRESLYKALSGKGNPTFDTILKVTKALGL 84
PRK09726 PRK09726
type II toxin-antitoxin system antitoxin HipB;
11-64 6.50e-04

type II toxin-antitoxin system antitoxin HipB;


Pssm-ID: 182049  Cd Length: 88  Bit Score: 37.65  E-value: 6.50e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 488251006  11 LGENIQTIRKHRGMKQQELADKIGINMQSLSKIERGVNYPTFDTLEKIMDVLGV 64
Cdd:PRK09726  13 LANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLEL 66
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 12-81 1.18e-03

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 39.33  E-value: 1.18e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 488251006  12 GENIQTIRKHRGMKQQEL---ADKIGINM--QSLSKIERGVNYPTFDTLEKIMDVLGVTPNELLSGEWKYIDHTE 81
Cdd:PRK13355   5 AERLKQAMKARGLKQEDLvhaAEARGVKLgkSHISQYVSGKTGPRRDVLPFLAAILGVSEDWLLGGESPADQESD 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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