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Conserved domains on  [gi|488283828|ref|WP_002355036|]
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MULTISPECIES: potassium channel family protein [Bacilli]

Protein Classification

potassium channel family protein( domain architecture ID 10545436)

potassium channel family protein spans the cell membrane to form a conduction pathway or pore, through which selective ions such as potassium, sodium, and calcium, translocate across cell membranes

Gene Ontology:  GO:0005267|GO:0034220|GO:0005216|GO:0071805|GO:0016020
PubMed:  15816170|9525859|11836519|11178249|1772658
SCOP:  4000034
TCDB:  1.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 37-100 3.10e-18

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


:

Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 73.07  E-value: 3.10e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488283828   37 SGTIFYSTVE--KLSPLDSLYLSFMTLTTIGYGDVHPVTDLGKIFTMVYATVGLGIMAMFISVVAK 100
Cdd:pfam07885   9 FGTVYYLLEEgwEWSFLDALYFSFVTLTTVGYGDIVPLTDAGRLFTIFYILIGIPLFAIFLAVLGR 74
 
Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 37-100 3.10e-18

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 73.07  E-value: 3.10e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488283828   37 SGTIFYSTVE--KLSPLDSLYLSFMTLTTIGYGDVHPVTDLGKIFTMVYATVGLGIMAMFISVVAK 100
Cdd:pfam07885   9 FGTVYYLLEEgwEWSFLDALYFSFVTLTTVGYGDIVPLTDAGRLFTIFYILIGIPLFAIFLAVLGR 74
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 53-95 6.98e-06

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 43.70  E-value: 6.98e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 488283828  53 SLYLSFMTLTTIGYGDVHPVTDLGKIFTMVYATVGLGIMAMFI 95
Cdd:PLN03192 254 AIYWSITTMTTVGYGDLHAVNTIEMIFIIFYMLFNLGLTAYLI 296
 
Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 37-100 3.10e-18

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 73.07  E-value: 3.10e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 488283828   37 SGTIFYSTVE--KLSPLDSLYLSFMTLTTIGYGDVHPVTDLGKIFTMVYATVGLGIMAMFISVVAK 100
Cdd:pfam07885   9 FGTVYYLLEEgwEWSFLDALYFSFVTLTTVGYGDIVPLTDAGRLFTIFYILIGIPLFAIFLAVLGR 74
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 53-95 6.98e-06

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 43.70  E-value: 6.98e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 488283828  53 SLYLSFMTLTTIGYGDVHPVTDLGKIFTMVYATVGLGIMAMFI 95
Cdd:PLN03192 254 AIYWSITTMTTVGYGDLHAVNTIEMIFIIFYMLFNLGLTAYLI 296
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 49-102 3.88e-05

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 41.10  E-value: 3.88e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488283828   49 SPLDSLYLSFMTLTTIGYGDVHPVTDLGK-------IFTMVYATVGLGIMAMFISVVAKSY 102
Cdd:pfam00520 170 NFPNAFLWLFQTMTTEGWGDIMYDTIDGKgefwayiYFVSFIILGGFLLLNLFIAVIIDNF 230
PRK10537 PRK10537
voltage-gated potassium channel protein;
54-99 2.99e-04

voltage-gated potassium channel protein;


Pssm-ID: 236711 [Multi-domain]  Cd Length: 393  Bit Score: 38.85  E-value: 2.99e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 488283828  54 LYLSFMTLTTIGYGDVHPVTDLGKIFTMVYATVGLGIMAMFISVVA 99
Cdd:PRK10537 173 FYFSIVTMSTVGYGDIVPVSESARLFTISVIILGITVFATSISAIF 218
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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