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Conserved domains on  [gi|488310537|ref|WP_002379922|]
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MULTISPECIES: pheromone response system RNA-binding regulator PrgU [Lactobacillales]

Protein Classification

PrgU domain-containing protein( domain architecture ID 10560333)

PrgU domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PrgU pfam09627
PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus ...
 2-106 5.70e-45

PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus bacteria. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. PrgU probably acts as a RNA-binding regulator that mitigates toxicity accompanying overproduction of PrgB-like adhesins, which are involved in conjugative transfer.


:

Pssm-ID: 462841  Cd Length: 105  Bit Score: 141.39  E-value: 5.70e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488310537    2 EAVVEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKS 81
Cdd:pfam09627   1 KEVVEREAKGTKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAEEIWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKS 80

                          90       100
                  ....*....|....*....|....*
gi 488310537   82 IYVKPNLGRINVPVFFIKTPINRGV 106
Cdd:pfam09627  81 IYVKPNLGRINVPVFFIKTPINRGV 105
 
Name Accession Description Interval E-value
PrgU pfam09627
PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus ...
 2-106 5.70e-45

PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus bacteria. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. PrgU probably acts as a RNA-binding regulator that mitigates toxicity accompanying overproduction of PrgB-like adhesins, which are involved in conjugative transfer.


Pssm-ID: 462841  Cd Length: 105  Bit Score: 141.39  E-value: 5.70e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488310537    2 EAVVEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKS 81
Cdd:pfam09627   1 KEVVEREAKGTKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAEEIWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKS 80

                          90       100
                  ....*....|....*....|....*
gi 488310537   82 IYVKPNLGRINVPVFFIKTPINRGV 106
Cdd:pfam09627  81 IYVKPNLGRINVPVFFIKTPINRGV 105
 
Name Accession Description Interval E-value
PrgU pfam09627
PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus ...
 2-106 5.70e-45

PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus bacteria. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. PrgU probably acts as a RNA-binding regulator that mitigates toxicity accompanying overproduction of PrgB-like adhesins, which are involved in conjugative transfer.


Pssm-ID: 462841  Cd Length: 105  Bit Score: 141.39  E-value: 5.70e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488310537    2 EAVVEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKS 81
Cdd:pfam09627   1 KEVVEREAKGTKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAEEIWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKS 80

                          90       100
                  ....*....|....*....|....*
gi 488310537   82 IYVKPNLGRINVPVFFIKTPINRGV 106
Cdd:pfam09627  81 IYVKPNLGRINVPVFFIKTPINRGV 105
PrgU pfam09627
PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus ...
 13-117 7.90e-44

PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus bacteria. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. PrgU probably acts as a RNA-binding regulator that mitigates toxicity accompanying overproduction of PrgB-like adhesins, which are involved in conjugative transfer.


Pssm-ID: 462841  Cd Length: 105  Bit Score: 138.70  E-value: 7.90e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488310537   13 KEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIYVKPNLGRIN 92
Cdd:pfam09627   1 KEVVEREAKGTKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAEEIWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKS 80

                          90       100
                  ....*....|....*....|....*
gi 488310537   93 VPVFFIKTPINRGVFEEIFGETLKA 117
Cdd:pfam09627  81 IYVKPNLGRINVPVFFIKTPINRGV 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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