NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|488327427|ref|WP_002396812|]
View 

MULTISPECIES: lichenicidin A2 family type 2 lantibiotic [Enterococcus]

Protein Classification

lant_SP_1948 family protein( domain architecture ID 10024047)

lant_SP_1948 family protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
lant_SP_1948 TIGR03893
type 2 lantibiotic, SP_1948 family; This model recognizes a number of type 2 lantibiotic-type ...
 5-64 1.35e-17

type 2 lantibiotic, SP_1948 family; This model recognizes a number of type 2 lantibiotic-type bacteriocins, related to but distinct from the family that includes lichenicidin and mersacidin. Sequence similarity among members consists largely of a 20-residue block of conserved sequence that covers most of the leader peptide region, absent from the mature lantibiotic. This is followed by a region with characteristic composition for lantibiotic precursor regions, rich in Ser and Thr and including a near-invariant Cys near or at the C-terminus, involved in cyclization. Members of this family typically are shorter than 70 amino acids. [Cellular processes, Toxin production and resistance]


:

Pssm-ID: 274837  Cd Length: 61  Bit Score: 68.67  E-value: 1.35e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488327427   5 QLDSLVGQKFEDLSKEEMNFIAGGND-NARISPTIILSAATVASAASSFVGSYTLSAFTKC 64
Cdd:TIGR03893  1 NNKKIVGDSFEELSIEEMALIQGSGDvNARTTPICVTVAAAVSSAAASFVVSYALSAVTKC 61
 
Name Accession Description Interval E-value
lant_SP_1948 TIGR03893
type 2 lantibiotic, SP_1948 family; This model recognizes a number of type 2 lantibiotic-type ...
 5-64 1.35e-17

type 2 lantibiotic, SP_1948 family; This model recognizes a number of type 2 lantibiotic-type bacteriocins, related to but distinct from the family that includes lichenicidin and mersacidin. Sequence similarity among members consists largely of a 20-residue block of conserved sequence that covers most of the leader peptide region, absent from the mature lantibiotic. This is followed by a region with characteristic composition for lantibiotic precursor regions, rich in Ser and Thr and including a near-invariant Cys near or at the C-terminus, involved in cyclization. Members of this family typically are shorter than 70 amino acids. [Cellular processes, Toxin production and resistance]


Pssm-ID: 274837  Cd Length: 61  Bit Score: 68.67  E-value: 1.35e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488327427   5 QLDSLVGQKFEDLSKEEMNFIAGGND-NARISPTIILSAATVASAASSFVGSYTLSAFTKC 64
Cdd:TIGR03893  1 NNKKIVGDSFEELSIEEMALIQGSGDvNARTTPICVTVAAAVSSAAASFVVSYALSAVTKC 61
 
Name Accession Description Interval E-value
lant_SP_1948 TIGR03893
type 2 lantibiotic, SP_1948 family; This model recognizes a number of type 2 lantibiotic-type ...
 5-64 1.35e-17

type 2 lantibiotic, SP_1948 family; This model recognizes a number of type 2 lantibiotic-type bacteriocins, related to but distinct from the family that includes lichenicidin and mersacidin. Sequence similarity among members consists largely of a 20-residue block of conserved sequence that covers most of the leader peptide region, absent from the mature lantibiotic. This is followed by a region with characteristic composition for lantibiotic precursor regions, rich in Ser and Thr and including a near-invariant Cys near or at the C-terminus, involved in cyclization. Members of this family typically are shorter than 70 amino acids. [Cellular processes, Toxin production and resistance]


Pssm-ID: 274837  Cd Length: 61  Bit Score: 68.67  E-value: 1.35e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 488327427   5 QLDSLVGQKFEDLSKEEMNFIAGGND-NARISPTIILSAATVASAASSFVGSYTLSAFTKC 64
Cdd:TIGR03893  1 NNKKIVGDSFEELSIEEMALIQGSGDvNARTTPICVTVAAAVSSAAASFVVSYALSAVTKC 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH