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Conserved domains on  [gi|488334426|ref|WP_002403811|]
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MULTISPECIES: glycoside hydrolase family 105 protein [Enterococcus]

Protein Classification

glycoside hydrolase family 105 protein( domain architecture ID 10008370)

glycoside hydrolase family 105 (GH105) protein similar to Bacillus subtilis unsaturated rhamnogalacturonyl hydrolases YetR and YesR, which catalyze the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YesR COG4225
Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];
44-364 6.38e-141

Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];


:

Pssm-ID: 443369  Cd Length: 336  Bit Score: 403.42  E-value: 6.38e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  44 VDDKSWTIWNWPQGVGLYGIYKNYRNTKSEKALQVVNDWFEGRMQEGA----PPKNVNTMAPLLTMAYLYEDTKDSKYIP 119
Cdd:COG4225   12 IDPGKFPKWDYTQGVTLYGLLKLAEATGDKKYLDYIKRWFDFFIDEGNtyklPPYNLDDIAPGLALLELYEQTGDPKYLK 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 120 YLEQWAEWVMEEMPRTNEGGLQHATygpENKNQLWDDTLMMTVLPLAKIGKLLNRLDYLEEAKHQFLIHIKYLQDKKSGL 199
Cdd:COG4225   92 AADTLADWQLNTQPRTSEGGFWHKK---IYPNQLWLDGLYMAVPFLAQYGKLTGDPKYFDDAAKQFLLTTKYLFDPETGL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 200 WYHGWTFEGN--HNYAEALWARGNCWITIAIPEIIEILelPKGDSLREFLLSTLNAQVAALAKYQDESGLWHTLINDSNS 277
Cdd:COG4225  169 YYHGWDESREqkAGGSPAFWGRGNGWVAMALVDLLDLL--PEDHPDRPELLALLKEMAAALAKYQDESGLWHQVLDDPGN 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 278 YLESSATAGFAYGILKAVHKKYISSEYEEVANKAIAGLLNKIDETGEVQHVSVGTGMGDNLDFYRTIGMTA-MPYGQSLT 356
Cdd:COG4225  247 YLETSATAMFTYALAKGVNKGYLDKKYLPAAEKAWNGLLKKIDEDGSLTGVCVGTGLGGSLEYYISEPIRTnDPYGVGPF 326


                 ....*...
gi 488334426 357 ILCLTELL 364
Cdd:COG4225  327 LLAGSEML 334
 
Name Accession Description Interval E-value
YesR COG4225
Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];
44-364 6.38e-141

Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];


Pssm-ID: 443369  Cd Length: 336  Bit Score: 403.42  E-value: 6.38e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  44 VDDKSWTIWNWPQGVGLYGIYKNYRNTKSEKALQVVNDWFEGRMQEGA----PPKNVNTMAPLLTMAYLYEDTKDSKYIP 119
Cdd:COG4225   12 IDPGKFPKWDYTQGVTLYGLLKLAEATGDKKYLDYIKRWFDFFIDEGNtyklPPYNLDDIAPGLALLELYEQTGDPKYLK 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 120 YLEQWAEWVMEEMPRTNEGGLQHATygpENKNQLWDDTLMMTVLPLAKIGKLLNRLDYLEEAKHQFLIHIKYLQDKKSGL 199
Cdd:COG4225   92 AADTLADWQLNTQPRTSEGGFWHKK---IYPNQLWLDGLYMAVPFLAQYGKLTGDPKYFDDAAKQFLLTTKYLFDPETGL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 200 WYHGWTFEGN--HNYAEALWARGNCWITIAIPEIIEILelPKGDSLREFLLSTLNAQVAALAKYQDESGLWHTLINDSNS 277
Cdd:COG4225  169 YYHGWDESREqkAGGSPAFWGRGNGWVAMALVDLLDLL--PEDHPDRPELLALLKEMAAALAKYQDESGLWHQVLDDPGN 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 278 YLESSATAGFAYGILKAVHKKYISSEYEEVANKAIAGLLNKIDETGEVQHVSVGTGMGDNLDFYRTIGMTA-MPYGQSLT 356
Cdd:COG4225  247 YLETSATAMFTYALAKGVNKGYLDKKYLPAAEKAWNGLLKKIDEDGSLTGVCVGTGLGGSLEYYISEPIRTnDPYGVGPF 326


                 ....*...
gi 488334426 357 ILCLTELL 364
Cdd:COG4225  327 LLAGSEML 334
Glyco_hydro_88 pfam07470
Glycosyl Hydrolase Family 88; Unsaturated glucuronyl hydrolase catalyzes the hydrolytic ...
 27-367 8.97e-105

Glycosyl Hydrolase Family 88; Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.


Pssm-ID: 429478  Cd Length: 345  Bit Score: 312.00  E-value: 8.97e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426   27 TIKDNTGEFLLDFDGLKVDD-KSWTIWNWPQGVGLYGIYKNYRNTKSEKALQVVNDWFEGRMQEGAP---PKNVNTMAPL 102
Cdd:pfam07470   1 YIDRVAGSFMKRYPDGKVIDlPPDNRWDWTNGVFLYGMLEAYEATGDKEYLDYLKAWADSLIDEGGKiltPYNLDDINIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  103 LTMAYLYEDTKDSKYIPYLEQWAEWVMEEMPRTNEGGLQHATYGPEnknQLWDDTLMMTVLPLAKIGKLLNRLDYLEEAK 182
Cdd:pfam07470  81 LTLLDLYEHTGDERYIQAAIELADWVLATPPRTSEGGFWHKDIYPH---QMWLDGLFMAGPFLAKYGKLTNEPKYLDEAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  183 HQFLIHIKYLQDKKSGLWYHGWTFEGNHNYAEALWARGNCWITIAIPEIIEilELPKGDSLREFLLSTLNAQVAALAKYQ 262
Cdd:pfam07470 158 YQFLLTRRHLYDPETGLYYHGWDESGTEPWADPFWARGNGWYAMALADVLE--LLPEKHPARQELINILRDLVKALAKYQ 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  263 DESGLWHTLI--NDSNSYLESSATAGFAYGILKAVHKKYISSEYEEVANKAIAGLL-NKIDETGE--VQHVSVGTGMGDN 337
Cdd:pfam07470 236 DESGLWHQSLddPDRDSYLETSASAGFVYALAKGVNKGYLDKKYLPVAQKAWKALLkNFVDEDGQlgVVQICGGTGIGGD 315

                         330       340       350
                  ....*....|....*....|....*....|..
gi 488334426  338 lDFY--RTIGMTAmPYGQSLTILCLTELLVSY 367
Cdd:pfam07470 316 -DYYrsVPYNSND-PYGVGAFLLASTEYLRLL 345
 
Name Accession Description Interval E-value
YesR COG4225
Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];
44-364 6.38e-141

Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];


Pssm-ID: 443369  Cd Length: 336  Bit Score: 403.42  E-value: 6.38e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  44 VDDKSWTIWNWPQGVGLYGIYKNYRNTKSEKALQVVNDWFEGRMQEGA----PPKNVNTMAPLLTMAYLYEDTKDSKYIP 119
Cdd:COG4225   12 IDPGKFPKWDYTQGVTLYGLLKLAEATGDKKYLDYIKRWFDFFIDEGNtyklPPYNLDDIAPGLALLELYEQTGDPKYLK 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 120 YLEQWAEWVMEEMPRTNEGGLQHATygpENKNQLWDDTLMMTVLPLAKIGKLLNRLDYLEEAKHQFLIHIKYLQDKKSGL 199
Cdd:COG4225   92 AADTLADWQLNTQPRTSEGGFWHKK---IYPNQLWLDGLYMAVPFLAQYGKLTGDPKYFDDAAKQFLLTTKYLFDPETGL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 200 WYHGWTFEGN--HNYAEALWARGNCWITIAIPEIIEILelPKGDSLREFLLSTLNAQVAALAKYQDESGLWHTLINDSNS 277
Cdd:COG4225  169 YYHGWDESREqkAGGSPAFWGRGNGWVAMALVDLLDLL--PEDHPDRPELLALLKEMAAALAKYQDESGLWHQVLDDPGN 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426 278 YLESSATAGFAYGILKAVHKKYISSEYEEVANKAIAGLLNKIDETGEVQHVSVGTGMGDNLDFYRTIGMTA-MPYGQSLT 356
Cdd:COG4225  247 YLETSATAMFTYALAKGVNKGYLDKKYLPAAEKAWNGLLKKIDEDGSLTGVCVGTGLGGSLEYYISEPIRTnDPYGVGPF 326


                 ....*...
gi 488334426 357 ILCLTELL 364
Cdd:COG4225  327 LLAGSEML 334
Glyco_hydro_88 pfam07470
Glycosyl Hydrolase Family 88; Unsaturated glucuronyl hydrolase catalyzes the hydrolytic ...
 27-367 8.97e-105

Glycosyl Hydrolase Family 88; Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.


Pssm-ID: 429478  Cd Length: 345  Bit Score: 312.00  E-value: 8.97e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426   27 TIKDNTGEFLLDFDGLKVDD-KSWTIWNWPQGVGLYGIYKNYRNTKSEKALQVVNDWFEGRMQEGAP---PKNVNTMAPL 102
Cdd:pfam07470   1 YIDRVAGSFMKRYPDGKVIDlPPDNRWDWTNGVFLYGMLEAYEATGDKEYLDYLKAWADSLIDEGGKiltPYNLDDINIG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  103 LTMAYLYEDTKDSKYIPYLEQWAEWVMEEMPRTNEGGLQHATYGPEnknQLWDDTLMMTVLPLAKIGKLLNRLDYLEEAK 182
Cdd:pfam07470  81 LTLLDLYEHTGDERYIQAAIELADWVLATPPRTSEGGFWHKDIYPH---QMWLDGLFMAGPFLAKYGKLTNEPKYLDEAV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  183 HQFLIHIKYLQDKKSGLWYHGWTFEGNHNYAEALWARGNCWITIAIPEIIEilELPKGDSLREFLLSTLNAQVAALAKYQ 262
Cdd:pfam07470 158 YQFLLTRRHLYDPETGLYYHGWDESGTEPWADPFWARGNGWYAMALADVLE--LLPEKHPARQELINILRDLVKALAKYQ 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 488334426  263 DESGLWHTLI--NDSNSYLESSATAGFAYGILKAVHKKYISSEYEEVANKAIAGLL-NKIDETGE--VQHVSVGTGMGDN 337
Cdd:pfam07470 236 DESGLWHQSLddPDRDSYLETSASAGFVYALAKGVNKGYLDKKYLPVAQKAWKALLkNFVDEDGQlgVVQICGGTGIGGD 315

                         330       340       350
                  ....*....|....*....|....*....|..
gi 488334426  338 lDFY--RTIGMTAmPYGQSLTILCLTELLVSY 367
Cdd:pfam07470 316 -DYYrsVPYNSND-PYGVGAFLLASTEYLRLL 345
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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